Ihara Motomasa 井原基公

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IHARA MOTOMASA 井原基公

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Researcher Number	50403506
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京医科歯科大学, 生体材料工学研究所, 非常勤講師 2020 – 2021: 国際医療福祉大学, 大学病院, 講師 2018: 東北大学, 医学系研究科, 大学院非常勤講師 2011 – 2017: 東北大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator Bnc1 / SUMO化 / 薬物徐放システム / 組織培養 / 卵胞 / IVA / 卵巣移植 / 生着率 / VEGF / 卵巣組織移植 … More / 卵胞活性化療法 / 徐放剤 / 加齢卵 / NLB / SUMO / 卵母細胞 / Basonuclin1 / エストロゲン受容体beta / 卵成熟 / 不妊 / 生殖 … More Except Principal Investigator ミトコンドリア / 配偶子系列遺伝子治療 / 核移植 / 卵細胞質 / 生殖医学 / ATRA / RARβ / RL95-2 / レチノイン酸受容体 / 子宮内膜癌 / アポトーシス / レチノイン酸 / 子宮内環境 / 次世代 / 高脂肪食 / 炎症 / インスリン抵抗性 / 肥満 / 妊娠 Less

Development of novel ovarian follicle maturation technique for improvement of ovarian functionPrincipal Investigator
- Principal Investigator
  
  Ihara Motomasa
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokyo Medical and Dental University
  International University of Health and Welfare
Challenge of overcoming recurrent IVF failure due to cytoplasmic dysfunction by MST: To secure safety in future generation
- Principal Investigator
  
  TACHIBANA Masahito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
レチノイン酸によるアポトーシス関連遺伝子を介した子宮内膜癌増殖制御機構の解明
- Principal Investigator
  
  宇都宮裕貴
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Analysis of nucleolus function and sumoylation in oocytePrincipal Investigator
- Principal Investigator
  
  IHARA Motomasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Maternal high-fat diet causes insulin resistance of offspring via inflammatory change in visceral fat using mice models - for a remedial strategy-
- Principal Investigator
  
  Sugiyama Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Ehime University
  Tohoku University
Functional analysis of estrogen receptor beta-targeting candidate gene Basonuclin1.Principal Investigator
- Principal Investigator
  
  IHARA MOTOMASA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University

All 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Spermatid Head Elongation with Normal Nuclear Shaping Requires ADP-Ribosyltransferase PARP11 (ARTD11) in Mice2015
- Author(s)
  Meyer-Ficca ML, Ihara M, Bader JJ, Leu NA, Beneke S, Meyer RG.
- Journal Title
  
  Biol Reprod.
  
  Volume: 92 Pages: 1-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462471
[Journal Article] Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression2014
- Author(s)
  Ihara M, Meyer-Ficca ML, Leu NA, Rao S, Li F, Gregory BD, Zalenskaya IA, Schultz RM, and Meyer RG
- Journal Title
  
  PLoS Genet
  
  Volume: 10(5) Issue: 5 Pages: e1004317-e1004317
- DOI
  10.1371/journal.pgen.1004317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791803
[Journal Article] Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression.2014
- Author(s)
  2)Ihara M, Meyer-Ficca ML, Leu NA, Rao S, Li F, Gregory BD, Zalenskaya IA, Schultz RM, Meyer RG.
- Journal Title
  
  PLOS Genetics
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462471
[Journal Article] Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation2013
- Author(s)
  Meyer-Ficca ML, Lonchar JD, Ihara M, Rader JJ, and Meyer RG
- Journal Title
  
  Chromosoma
  
  Volume: 122(4) Issue: 4 Pages: 319-335
- DOI
  10.1007/s00412-013-0416-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791803
[Journal Article] 活性酸素 : 生殖細胞と酸化ストレス2013
- Author(s)
  井原基公、有馬隆博
- Journal Title
  
  医歯薬出版「医学のあゆみ」
  
  Pages: 851-855
- Data Source
  KAKENHI-PROJECT-23791803
[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2017
- Author(s)
  井原基公
- Organizer
  第69回日本産科婦人科学会学術講演会
- Place of Presentation
  広島・リーガロイヤルホテル
- Year and Date
  2017-04-13
- Data Source
  KAKENHI-PROJECT-26462471
[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2016
- Author(s)
  井原基公
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台・仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26462471
[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2016
- Author(s)
  井原基公
- Organizer
  第５４回日本生殖医学会東北支部会
- Place of Presentation
  岩手・岩手医科大学
- Data Source
  KAKENHI-PROJECT-26462471
[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2016
- Author(s)
  井原基公
- Organizer
  第61回日本生殖医学会学術講演会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26462471
[Presentation] ポリ(ADP-リボシル)化反応異常はヘテロクロマチンの凝縮障害によって精子の核構造に影響する2013
- Author(s)
  井原基公, Mirella L. Meyer-Ficca, Julia D. Lonchar, Jessica J. Bader,八重樫伸生, Ralph G. Meyer
- Organizer
  第61回北日本産科婦人科学会学術講演会
- Place of Presentation
  旭川市
- Year and Date
  2013-09-07
- Data Source
  KAKENHI-PROJECT-23791803
[Presentation] Basonuclin1は卵母細胞・着床前期胚におけるribosomal RNA variantの遺伝子発現制御に関与しない2012
- Author(s)
  井原基公・Hung Tseng・Richard M. Schultz
- Organizer
  第52回日本哺乳動物卵子学会学術集会
- Place of Presentation
  大田原市
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PROJECT-23791803
[Presentation] 精子形成期のポリ(ADP-リボシル)化反応は初期胚遺伝子発現制御に関与する2012
- Author(s)
  井原基公, Mirella L. Meyer-Ficca, Richard M. Schultz, Jessica J. Bader,菅原準一,八重樫伸生, Ralph G. Meyer
- Organizer
  第57回日本生殖医学会学術講演会
- Place of Presentation
  長崎市
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-23791803
[Presentation] 精子におけるポリ(ADPリボース)化反応異常は初期胚における遺伝子発現に影響する2011
- Author(s)
  井原基公, Mirella L. Meyer-Ficca, Julia D. Lonchar,菅原純一,八重樫伸生, Ralph G. Meyer
- Organizer
  第56回日本生殖医学会学術講演会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23791803
[Presentation] 精子におけるポリ(ADP-リボ-ス)化反応異常は初期胚における遺伝子発現に影響する2011
- Author(s)
  井原基公, Mirella L. Meyer-Ficca, Julia Lonchar, Kenneth J. McLaughlin,菅原準一,八重樫伸生, Richard M. Schultz, and Ralph G. Meyer
- Organizer
  第59回北日本産科婦人科学会学術講演会
- Place of Presentation
  秋田市
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23791803

1. 宇都宮裕貴 (10359507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TACHIBANA Masahito (30431571)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Sugiyama Takashi (10263005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Kimura Yoshitaka (40261622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Sugawara Junichi (60280880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鈴木史彦 (20400343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 坂本雅弘 (50645299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 志賀尚美 (20595558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 渡邉善 (40722567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 黒澤大樹 (20770192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 河村和弘 (10344756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ihara Motomasa 井原 基公

IHARA MOTOMASA 井原 基公

Research Projects

Research Products

Co-Researchers

Development of novel ovarian follicle maturation technique for improvement of ovarian functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Challenge of overcoming recurrent IVF failure due to cytoplasmic dysfunction by MST: To secure safety in future generation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レチノイン酸によるアポトーシス関連遺伝子を介した子宮内膜癌増殖制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of nucleolus function and sumoylation in oocytePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maternal high-fat diet causes insulin resistance of offspring via inflammatory change in visceral fat using mice models - for a remedial strategy-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of estrogen receptor beta-targeting candidate gene Basonuclin1.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Spermatid Head Elongation with Normal Nuclear Shaping Requires ADP-Ribosyltransferase PARP11 (ARTD11) in Mice2015

Author(s)

Journal Title

Data Source

[Journal Article] Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression.2014

Author(s)

Journal Title

Data Source

[Journal Article] Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 活性酸素 : 生殖細胞と酸化ストレス2013

Author(s)

Journal Title

Data Source

[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 卵母細胞に高発現するBasonuclin1のSUMO化はPias4によって促進される2016

Author(s)

Organizer

Place of Presentation

Data Source

Ihara Motomasa 井原基公

IHARA MOTOMASA 井原基公