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Fujimoto Kenta  藤本 健太

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FUJIMOTO Kenta  藤本 健太

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Researcher Number 50403580
Other IDs
Affiliation (Current) 2025: 日本医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2025: 日本医科大学, 医学部, 准教授
2017: 日本医科大学, 医学部, 講師
2013 – 2015: 埼玉医科大学, 医学部, 助教
2012: 埼玉医科大学, 医学部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 48010:Anatomy-related / Genome biology
Except Principal Investigator
Morphology/Structure / General medical chemistry
Keywords
Principal Investigator
発現制御 / メチル化 / 遺伝子発現制御 / RNA結合タンパク質 / 長鎖非コードRNA
Except Principal Investigator
Wntシグナル伝達経路 / アフリカツメガエル / 培養 / 変態 / 甲状腺ホルモン … More / Wntシグナル経路 / Ror2 / 幹細胞 / 小腸 / 長鎖非コードRNA / メチル化 / 発現制御 / 生体分子 / 核酸 / 遺伝子 / 酵素 Less
  • Research Projects

    (4 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (9 People)
  •  甲状腺ホルモンにより成体型システムに転換する腸管神経系でのWntシグナル経路の解明Principal Investigator

    • Principal Investigator
      藤本 健太
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Nippon Medical School
  •  Lineage analysis of intestinal stem cells and development of the culture system to study the stem cell niche

    • Principal Investigator
      ISHIZUYA-OKA Atsuko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphology/Structure
    • Research Institution
      Nippon Medical School
  •  Elucidation of molecular mechanism of function of long noncoding RNAs through methylation signal

    • Principal Investigator
      KUROKAWA RIKI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Saitama Medical University
  •  Role of methylation of RNA-biding protein on transcriptional repression by the long non-coding RNAPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Kenta
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Genome biology
    • Research Institution
      Saitama Medical University

All 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation Patent

  • [Journal Article] Essential roles of thyroid hormone-regulated hyaluronan/CD44 signaling in adult stem cell development during Xenopus laevis intestinal remodeling2017

    • Author(s)
      Hasebe T, Fujimoto K, Kajita M, Ishizuya-Oka A
    • Journal Title

      Stem Cells

      Volume: 35 Issue: 10 Pages: 2175-2183

    • DOI

      10.1002/stem.2671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07475, KAKENHI-PROJECT-15K07136
  • [Journal Article] Thyroid hormone-induced activation of Notch signaling is required for adult intestinal stem cell development during Xenopus laevis metamorphosis2017

    • Author(s)
      Hasebe T, Fujimoto K, Kajita M, Fu L, Shi Y-B, Ishizuya-Oka A
    • Journal Title

      Stem Cells

      Volume: 35 Issue: 4 Pages: 1028-1039

    • DOI

      10.1002/stem.2544

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25440160, KAKENHI-PROJECT-15K07136
  • [Journal Article] Thyroid hormone activates Wnt/beta-catenin signaling involved in adult epithelial development during Xenopus laevis intestinal remodeling2016

    • Author(s)
      Hasebe, T., Fujimoto K., Kajita M., Ishizuya-Oka, A.
    • Journal Title

      Cell & Tissue Research

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Journal Article] Histone Methylation and STAT-3 Differentially Regulate Interleukin-6-Induced Matrix Metalloproteinase Gene Activation in Rheumatoid Arthritis Synovial Fibroblasts.2016

    • Author(s)
      Araki Y, Tsuzuki Wada T, Aizaki Y, Sato K, Yokota K, Fujimoto K, Kim YT, Oda H, Kurokawa R, Mimura
    • Journal Title

      Arthritis Rheumatol.

      Volume: 68 Issue: 5 Pages: 1111-23

    • DOI

      10.1002/art.39563

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10488, KAKENHI-PROJECT-25461482, KAKENHI-PROJECT-25462379, KAKENHI-PROJECT-25293073, KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K09903
  • [Journal Article] Development of a mouse monoclonal antibody for the detection of asymmetric dimethylarginine of Translocated in LipoSarcoma/FUsed in Sarcoma and its application in analyzing methylated TLS.2014

    • Author(s)
      Fujimoto, K., and Kurokawa, R.
    • Journal Title

      Cell & Bioscience

      Volume: 4 Issue: 1 Pages: 77-77

    • DOI

      10.1186/2045-3701-4-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293073
  • [Journal Article] Implicated role of liposarcoma related fusion oncoprotein TLS-CHOP in the dysregulaiton of arginine-specific methylation through PRMT12013

    • Author(s)
      Kenta Fujimoto, Shigeki Arai, Maki Matsubara, Kun Du, Yasuto Araki, Akio Matsushita, Riki Kurokawa
    • Journal Title

      Cell Biology

      Volume: Vol.1、No.2 Issue: 2 Pages: 18-23

    • DOI

      10.11648/j.cb.20130102.11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24810023, KAKENHI-PROJECT-25462379
  • [Patent] 抗TLSモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、 並びに抗TLSモノクローナル抗体含有組成物2013

    • Inventor(s)
      黒川理樹、藤本健太
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-099962
    • Filing Date
      2013-05-10
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Patent] 抗TLSモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗TLSモノクローナル抗体含有組成物2013

    • Inventor(s)
      黒川理樹、藤本健太
    • Industrial Property Rights Holder
      黒川理樹、藤本健太
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-099962
    • Filing Date
      2013-05-10
    • Data Source
      KAKENHI-PROJECT-25293073
  • [Patent] 抗TLSモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗TLSモノクローナル抗体含有組成物2013

    • Inventor(s)
      黒川 理樹、藤本 健太
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-099962
    • Filing Date
      2013-05-10
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] アフリカツメガエル小腸におけるヒアルロン酸シグナルの幹細胞ニッチ形成に果たす役割2018

    • Author(s)
      藤本健太、長谷部孝、梶田満子、岡敦子
    • Organizer
      第123回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Presentation] アフリカツメガエルの小腸再構築におけるヒアルロン酸シグナルの役割2017

    • Author(s)
      藤本健太、長谷部孝、梶田満子、岡敦子
    • Organizer
      第50回日本発生生物会大会
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Presentation] アフリカツメガエル小腸上皮の幹細胞制御におけるヒアルロン酸/CD44シグナルの役割2017

    • Author(s)
      長谷部孝、藤本健太、梶田満子、岡敦子
    • Organizer
      第88回日本動物学会
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Presentation] アフリカツメガエルの消化管再構築においてWntシグナルは甲状腺ホルモンにより活性化され成体型上皮の発生に関与する2016

    • Author(s)
      長谷部 孝、藤本 健太、岡 敦子
    • Organizer
      第57回日本組織細胞化学会学術集会
    • Place of Presentation
      杏林大学井の頭キャンパス(東京・三鷹)
    • Year and Date
      2016-09-03
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Presentation] Thyroid hormone-induced activation of Notch signaling is required for intestinal remodeling during Xenopus laevis metamorphosis2016

    • Author(s)
      長谷部 孝、藤本 健太、梶田 満子、Fu L.、Shi Y.-B.、岡 敦子
    • Organizer
      第87回日本動物学会大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄・宜野湾)
    • Year and Date
      2016-11-17
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Presentation] アフリカツメガエルの消化管再構築におけるヒアルロン酸合成酵素の遺伝子発現解析2016

    • Author(s)
      藤本 健太、長谷部 孝、梶田 満子、岡 敦子
    • Organizer
      第39回日本分子生物会大会
    • Place of Presentation
      パシフィコ横浜(神奈川・横浜)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15K07136
  • [Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein arginine methylation of RNA-biding protein TLS.2014

    • Author(s)
      Fujimoto, K., Suzuki, S., Kurokawa, R.
    • Organizer
      IIAS Research Conference 2014 Chromatin Decoding
    • Place of Presentation
      京都府木津川市(国際高等研究所)
    • Year and Date
      2014-05-13
    • Data Source
      KAKENHI-PROJECT-25293073
  • [Presentation] 筋萎縮性側索硬化症原因タンパク質TLSのメチル化と転写制御2013

    • Author(s)
      藤本健太、鈴木志穂、黒川理樹
    • Organizer
      第11回RCGMフォロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学創立30周年記念講堂(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] 長鎖非コードRNA結合タンパク質TLSのアルギニンメチル化 制御破綻による神経変性機構の解明2013

    • Author(s)
      藤本健太、鈴木志穂、黒川理樹
    • Organizer
      第11回RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学創立30周年記念講堂(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein methylation of nuclear hormone receptor-cofactor TLS2013

    • Author(s)
      Kenta Fujimoto, Shiho Suzuki, Riki Kurokawa
    • Organizer
      ENDO2013
    • Place of Presentation
      Moscone Center (San Francisco, California, USA)
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein arginine methylation of nuclear hormone receptor-cofactor TLS2013

    • Author(s)
      Kenta Fujimoto, Shiho Suzuki, Riki Kurokawa
    • Organizer
      ENDO2013
    • Place of Presentation
      Moscone Center (San Francisco, California, USA)
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein arginine methylation of nuclear hormone receptor-cofactor TLS.2013

    • Author(s)
      Fujimoto, K., Suzuki, S., and Kurokawa, R.
    • Organizer
      ENDO2013
    • Place of Presentation
      San Francisco, California, USA
    • Data Source
      KAKENHI-PROJECT-25293073
  • [Presentation] cyclin D1プロモーター由来長鎖非コードRNAによるTLSのアルギニンメチル化修飾を介した転写制御2012

    • Author(s)
      藤本健太、鈴木志穂、黒川理樹
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] 筋萎縮性側索硬化症原因タンパク質TLSのメチル化と転写制御2012

    • Author(s)
      藤本健太
    • Organizer
      第10回RCGMフロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学創立30周年記念講堂(埼玉県)
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] 筋萎縮性側索硬化症原因タンパク質TLSのメチル化と転写制御2012

    • Author(s)
      藤本健太、鈴木志穂、黒川理樹
    • Organizer
      第10回RCGMフォロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学創立30周年記念講堂(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-24810023
  • [Presentation] cyclin D1プロモーター由来長鎖非コードRNAによるTLSのアルギニンメチル化修飾を 介した転写制御

    • Author(s)
      藤本健太
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-24810023
  • 1.  KUROKAWA RIKI (70170107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 2.  MATSUSITA AKIO (50402269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  OGAWA SUMITO (20323579)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ISHIZUYA-OKA Atsuko (50175254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 5.  HASEBE Takashi (70329027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 6.  AIZAKI Yoshimi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  ARAKI Yasuto
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  MIMURA Toshihide
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  佐藤 浩二郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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