Fujimoto Kenta 藤本健太

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FUJIMOTO Kenta 藤本健太

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Researcher Number	50403580
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 日本医科大学, 医学部, 准教授 2017: 日本医科大学, 医学部, 講師 2013 – 2015: 埼玉医科大学, 医学部, 助教 2012: 埼玉医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / Genome biology Except Principal Investigator Morphology/Structure / General medical chemistry
Keywords	Principal Investigator 発現制御 / メチル化 / 遺伝子発現制御 / RNA結合タンパク質 / 長鎖非コードRNA Except Principal Investigator Wntシグナル伝達経路 / アフリカツメガエル / 培養 / 変態 / 甲状腺ホルモン … More / Wntシグナル経路 / Ror2 / 幹細胞 / 小腸 / 長鎖非コードRNA / メチル化 / 発現制御 / 生体分子 / 核酸 / 遺伝子 / 酵素 Less

甲状腺ホルモンにより成体型システムに転換する腸管神経系でのWntシグナル経路の解明Principal Investigator
- Principal Investigator
  
  藤本健太
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Nippon Medical School
Lineage analysis of intestinal stem cells and development of the culture system to study the stem cell niche
- Principal Investigator
  
  ISHIZUYA-OKA Atsuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Nippon Medical School
Elucidation of molecular mechanism of function of long noncoding RNAs through methylation signal
- Principal Investigator
  
  KUROKAWA RIKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Saitama Medical University
Role of methylation of RNA-biding protein on transcriptional repression by the long non-coding RNAPrincipal Investigator
- Principal Investigator
  
  FUJIMOTO Kenta
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Genome biology
- Research Institution
  Saitama Medical University

All 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] Essential roles of thyroid hormone-regulated hyaluronan/CD44 signaling in adult stem cell development during Xenopus laevis intestinal remodeling2017
- Author(s)
  Hasebe T, Fujimoto K, Kajita M, Ishizuya-Oka A
- Journal Title
  
  Stem Cells
  
  Volume: 35 Issue: 10 Pages: 2175-2183
- DOI
  10.1002/stem.2671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07475, KAKENHI-PROJECT-15K07136
[Journal Article] Thyroid hormone-induced activation of Notch signaling is required for adult intestinal stem cell development during Xenopus laevis metamorphosis2017
- Author(s)
  Hasebe T, Fujimoto K, Kajita M, Fu L, Shi Y-B, Ishizuya-Oka A
- Journal Title
  
  Stem Cells
  
  Volume: 35 Issue: 4 Pages: 1028-1039
- DOI
  10.1002/stem.2544
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440160, KAKENHI-PROJECT-15K07136
[Journal Article] Thyroid hormone activates Wnt/beta-catenin signaling involved in adult epithelial development during Xenopus laevis intestinal remodeling2016
- Author(s)
  Hasebe, T., Fujimoto K., Kajita M., Ishizuya-Oka, A.
- Journal Title
  
  Cell & Tissue Research
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07136
[Journal Article] Histone Methylation and STAT-3 Differentially Regulate Interleukin-6-Induced Matrix Metalloproteinase Gene Activation in Rheumatoid Arthritis Synovial Fibroblasts.2016
- Author(s)
  Araki Y, Tsuzuki Wada T, Aizaki Y, Sato K, Yokota K, Fujimoto K, Kim YT, Oda H, Kurokawa R, Mimura
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 68 Issue: 5 Pages: 1111-23
- DOI
  10.1002/art.39563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10488, KAKENHI-PROJECT-25461482, KAKENHI-PROJECT-25462379, KAKENHI-PROJECT-25293073, KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K09903
[Journal Article] Development of a mouse monoclonal antibody for the detection of asymmetric dimethylarginine of Translocated in LipoSarcoma/FUsed in Sarcoma and its application in analyzing methylated TLS.2014
- Author(s)
  Fujimoto, K., and Kurokawa, R.
- Journal Title
  
  Cell & Bioscience
  
  Volume: 4 Issue: 1 Pages: 77-77
- DOI
  10.1186/2045-3701-4-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293073
[Journal Article] Implicated role of liposarcoma related fusion oncoprotein TLS-CHOP in the dysregulaiton of arginine-specific methylation through PRMT12013
- Author(s)
  Kenta Fujimoto, Shigeki Arai, Maki Matsubara, Kun Du, Yasuto Araki, Akio Matsushita, Riki Kurokawa
- Journal Title
  
  Cell Biology
  
  Volume: Vol.1、No.2 Issue: 2 Pages: 18-23
- DOI
  10.11648/j.cb.20130102.11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24810023, KAKENHI-PROJECT-25462379
[Patent] 抗ＴＬＳモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗ＴＬＳモノクローナル抗体含有組成物2013
- Inventor(s)
  黒川理樹、藤本健太
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-099962
- Filing Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-24810023
[Patent] 抗ＴＬＳモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗ＴＬＳモノクローナル抗体含有組成物2013
- Inventor(s)
  黒川理樹、藤本健太
- Industrial Property Rights Holder
  黒川理樹、藤本健太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-099962
- Filing Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-25293073
[Patent] 抗TLSモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗TLSモノクローナル抗体含有組成物2013
- Inventor(s)
  黒川理樹、藤本健太
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-099962
- Filing Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] アフリカツメガエル小腸におけるヒアルロン酸シグナルの幹細胞ニッチ形成に果たす役割2018
- Author(s)
  藤本健太、長谷部孝、梶田満子、岡敦子
- Organizer
  第123回日本解剖学会
- Data Source
  KAKENHI-PROJECT-15K07136
[Presentation] アフリカツメガエルの小腸再構築におけるヒアルロン酸シグナルの役割2017
- Author(s)
  藤本健太、長谷部孝、梶田満子、岡敦子
- Organizer
  第50回日本発生生物会大会
- Data Source
  KAKENHI-PROJECT-15K07136
[Presentation] アフリカツメガエル小腸上皮の幹細胞制御におけるヒアルロン酸/CD44シグナルの役割2017
- Author(s)
  長谷部孝、藤本健太、梶田満子、岡敦子
- Organizer
  第88回日本動物学会
- Data Source
  KAKENHI-PROJECT-15K07136
[Presentation] アフリカツメガエルの消化管再構築においてWntシグナルは甲状腺ホルモンにより活性化され成体型上皮の発生に関与する2016
- Author(s)
  長谷部孝、藤本健太、岡敦子
- Organizer
  第57回日本組織細胞化学会学術集会
- Place of Presentation
  杏林大学井の頭キャンパス（東京・三鷹）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-15K07136
[Presentation] Thyroid hormone-induced activation of Notch signaling is required for intestinal remodeling during Xenopus laevis metamorphosis2016
- Author(s)
  長谷部孝、藤本健太、梶田満子、Fu L.、Shi Y.-B.、岡敦子
- Organizer
  第87回日本動物学会大会
- Place of Presentation
  沖縄コンベンションセンター（沖縄・宜野湾）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K07136
[Presentation] アフリカツメガエルの消化管再構築におけるヒアルロン酸合成酵素の遺伝子発現解析2016
- Author(s)
  藤本健太、長谷部孝、梶田満子、岡敦子
- Organizer
  第39回日本分子生物会大会
- Place of Presentation
  パシフィコ横浜（神奈川・横浜）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K07136
[Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein arginine methylation of RNA-biding protein TLS.2014
- Author(s)
  Fujimoto, K., Suzuki, S., Kurokawa, R.
- Organizer
  IIAS Research Conference 2014 Chromatin Decoding
- Place of Presentation
  京都府木津川市(国際高等研究所)
- Year and Date
  2014-05-13
- Data Source
  KAKENHI-PROJECT-25293073
[Presentation] 筋萎縮性側索硬化症原因タンパク質TLSのメチル化と転写制御2013
- Author(s)
  藤本健太、鈴木志穂、黒川理樹
- Organizer
  第11回RCGMフォロンティアシンポジウム
- Place of Presentation
  埼玉医科大学創立30周年記念講堂(埼玉県日高市)
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] 長鎖非コードRNA結合タンパク質TLSのアルギニンメチル化制御破綻による神経変性機構の解明2013
- Author(s)
  藤本健太、鈴木志穂、黒川理樹
- Organizer
  第１１回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学創立３０周年記念講堂（埼玉県日高市）
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein methylation of nuclear hormone receptor-cofactor TLS2013
- Author(s)
  Kenta Fujimoto, Shiho Suzuki, Riki Kurokawa
- Organizer
  ENDO2013
- Place of Presentation
  Moscone Center (San Francisco, California, USA)
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein arginine methylation of nuclear hormone receptor-cofactor TLS2013
- Author(s)
  Kenta Fujimoto, Shiho Suzuki, Riki Kurokawa
- Organizer
  ENDO2013
- Place of Presentation
  Moscone Center (San Francisco, California, USA)
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] Transcriptional regulation by the long non-coding RNA transcribed from cyclin D1 promoter via protein arginine methylation of nuclear hormone receptor-cofactor TLS.2013
- Author(s)
  Fujimoto, K., Suzuki, S., and Kurokawa, R.
- Organizer
  ENDO2013
- Place of Presentation
  San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-25293073
[Presentation] cyclin D1プロモーター由来長鎖非コードRNAによるTLSのアルギニンメチル化修飾を介した転写制御2012
- Author(s)
  藤本健太、鈴木志穂、黒川理樹
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県福岡市)
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] 筋萎縮性側索硬化症原因タンパク質TLSのメチル化と転写制御2012
- Author(s)
  藤本健太
- Organizer
  第10回RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学創立30周年記念講堂（埼玉県）
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] 筋萎縮性側索硬化症原因タンパク質TLSのメチル化と転写制御2012
- Author(s)
  藤本健太、鈴木志穂、黒川理樹
- Organizer
  第10回RCGMフォロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学創立30周年記念講堂(埼玉県日高市)
- Data Source
  KAKENHI-PROJECT-24810023
[Presentation] cyclin D1プロモーター由来長鎖非コードRNAによるTLSのアルギニンメチル化修飾を介した転写制御
- Author(s)
  藤本健太
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-24810023

1. KUROKAWA RIKI (70170107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. MATSUSITA AKIO (50402269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OGAWA SUMITO (20323579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIZUYA-OKA Atsuko (50175254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. HASEBE Takashi (70329027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. AIZAKI Yoshimi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ARAKI Yasuto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. MIMURA Toshihide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 佐藤浩二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujimoto Kenta 藤本 健太

FUJIMOTO Kenta 藤本 健太

Research Projects

Research Products

Co-Researchers

甲状腺ホルモンにより成体型システムに転換する腸管神経系でのWntシグナル経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Lineage analysis of intestinal stem cells and development of the culture system to study the stem cell niche

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of molecular mechanism of function of long noncoding RNAs through methylation signal

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of methylation of RNA-biding protein on transcriptional repression by the long non-coding RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Essential roles of thyroid hormone-regulated hyaluronan/CD44 signaling in adult stem cell development during Xenopus laevis intestinal remodeling2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thyroid hormone-induced activation of Notch signaling is required for adult intestinal stem cell development during Xenopus laevis metamorphosis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thyroid hormone activates Wnt/beta-catenin signaling involved in adult epithelial development during Xenopus laevis intestinal remodeling2016

Author(s)

Journal Title

Data Source

[Journal Article] Histone Methylation and STAT-3 Differentially Regulate Interleukin-6-Induced Matrix Metalloproteinase Gene Activation in Rheumatoid Arthritis Synovial Fibroblasts.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a mouse monoclonal antibody for the detection of asymmetric dimethylarginine of Translocated in LipoSarcoma/FUsed in Sarcoma and its application in analyzing methylated TLS.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Implicated role of liposarcoma related fusion oncoprotein TLS-CHOP in the dysregulaiton of arginine-specific methylation through PRMT12013

Author(s)

Journal Title

DOI

Data Source

[Patent] 抗ＴＬＳモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、 並びに抗ＴＬＳモノクローナル抗体含有組成物2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] 抗ＴＬＳモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗ＴＬＳモノクローナル抗体含有組成物2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] 抗TLSモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗TLSモノクローナル抗体含有組成物2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] アフリカツメガエル小腸におけるヒアルロン酸シグナルの幹細胞ニッチ形成に果たす役割2018

Fujimoto Kenta 藤本健太

FUJIMOTO Kenta 藤本健太

[Patent] 抗ＴＬＳモノクローナル抗体及びその製造方法、ハイブリドーマ及びその製造方法、並びに抗ＴＬＳモノクローナル抗体含有組成物2013

[Presentation] 長鎖非コードRNA結合タンパク質TLSのアルギニンメチル化制御破綻による神経変性機構の解明2013