Watanabe Norihiko 渡部則彦

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WATANABE Norihiko 渡部則彦

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Researcher Number	50419446
Affiliation (Current)	2022: 京都大学, 医学研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2012 – 2013: 京都大学, 医学(系)研究科(研究院), 非常勤講師 2011: 京都大学, 医学(系)研究科(研究院), 准教授 2007 – 2010: Kyoto University, Department of Gastroenterology, Associate Professor 2006: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Biological Sciences Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 細胞・組織 / 免疫 / 生体分子 / 内科学 / 免疫学 / 癌 / 分化・増殖 / 感染症 / 肝臓病学 / 劇症肝炎 … More / 自己免疫性肝炎 / 消化管免疫 / サイトカイン / ケモカイン / 内科 / 発現制御 / 病理学 / Inflammatory bowel disease / Chronic inflammation / Dendritic cells / T cell differentiation / Epithelial cells / Cytokines / Infection / Toll-like receptorligand … More Except Principal Investigator AID / 炎症 / 発癌 / 遺伝子変異 / H. pylori / REG蛋白 / 染色体不安定性 / reg蛋白 / STAT3 / IFNγ / NFκB / タイプ4分泌装置 / H.pylori / 潰瘍性大腸炎 / Activation-induced cytidine deaminase(AID) / P53 Less

Immune mechanisms involved in the development of fatal autoimmune hepatitis in micePrincipal Investigator
- Principal Investigator
  
  WATANABE Norihiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Immunologic response to Helicobacter involved in the development of chronic gastritisPrincipal Investigator
- Principal Investigator
  
  WATANABE Norihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
ヒト樹状細胞活性化因子TSLPを用いた新規腫瘍特異的免疫療法の開発Principal Investigator
- Principal Investigator
  
  渡部則彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Mechanism for inflammation-associated gastrointestinal carcinogenesis.
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Elucidation of pathaphysiological roles of human thymic stromal lymphopoietin (TSLP) in inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  WATANABE Norihiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University

All 2014 2013 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] H.pylori infection-The route from inflammation to cancer. In Sansonetti P, ed, Infection Biology Handbook Series. Bacterial Virulence. Basic principles, models and global approaches.2010
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Publisher
  Willey-Blackwell
- Data Source
  KAKENHI-PROJECT-20390207
[Book] H.pylori infection .The route from inflammation to cancer. In Sansonetti P, ed, Infection Biology Handbook Series. Bacterial Virulence.2010
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Publisher
  Basic principles, models and global approaches. Willey-Blackwell
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Progression of autoimmune hepatitis is mediated by IL-18-producing dendritic cells and hepatic CXCL9 expression in mice.2014
- Author(s)
  Ikeda A, Aoki N, Kido M, Iwamoto S, Nishiura H, Maruoka R, Chiba T, Watanabe N
- Journal Title
  
  Hepatology
  
  Volume: (Epub ahead of print) Pages: 224-236
- DOI
  10.1002/hep.27087
- NAID
  120005656509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] TNF-αis essential in the induction of fatal autoimmune hepatitis in mice through upregulation of hepatic CCL20 expression2013
- Author(s)
  Iwamoto S
- Journal Title
  
  Clinical Immunology
  
  Volume: 146 Pages: 15-25
- DOI
  10.1016/j.clim.2012.10.008
- NAID
  120005147733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24659151
[Journal Article] Splenectomy prolongs the effects of corticosteroids in mouse models of autoimmune hepatitis2013
- Author(s)
  Maruoka R
- Journal Title
  
  Gastroenterology
  
  Volume: - Pages: 209-220
- DOI
  10.1053/j.gastro.2013.03.011
- NAID
  120005315980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Interleukin-21 and TNF-αare critical for the development of autoimmune gastritis in mice2013
- Author(s)
  Nishiura H
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: - Pages: 982-991
- DOI
  10.1111/jgh.12144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling.2012
- Author(s)
  中島沙恵子、椛島健治, 他
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 129 Pages: 1048-1055
- DOI
  10.1016/j.jaci.2012.01.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00216, KAKENHI-PROJECT-12J04619, KAKENHI-PLANNED-23116101, KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-23659203, KAKENHI-ORGANIZER-24111001
[Journal Article] Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient Mice.2012
- Author(s)
  Nishiura H, Kido M, Aoki N, Iwamoto S, Maruoka R, Ikeda A, Chiba T,Ziegler SF, Watanabe N
- Journal Title
  
  J Immunol.
  
  Volume: 188 Pages: 190-197
- DOI
  10.4049/jimmunol.1003787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Long-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori : a multicentre cohort follow-up study of 420 patients in Japan2012
- Author(s)
  Nakamura S, Sugiyama T, Matsumoto T, Iijima K, Ono S, Tajika M, TariA, Kitadai Y, Matsumoto H, Nagaya T, Kamoshida T, Watanabe N, Chiba T, Origasa H, Asaka M; for the JAPAN GAST Study Group
- Journal Title
  
  Gut
  
  Volume: 61 Pages: 507-513
- DOI
  10.1136/gutjnl-2011-300495
- NAID
  10030575954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590973
[Journal Article] IFN-Y is reciprocally involved in the concurrent development of organ-specific autoimmunity in the liver and stomach2012
- Author(s)
  Iwamoto S, Kido M, Aoki N, Nishiura H, Maruoka R, Ikeda A, Okazaki T, Chiba T, Watanabe N
- Journal Title
  
  Autoimmunity
  
  Volume: 45 Pages: 186-198
- DOI
  10.3109/08916934.2011.616559
- NAID
  120003752112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PUBLICLY-22021030, KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice2011
- Author(s)
  N. Aoki, M. Kido, S. Iwamoto, H. Nishiura, R. Maruoka, J. Tanaka, T. Watanabe, Y. Tanaka, T. Okazaki, T. Chiba, N. Watanabe
- Journal Title
  
  Gastroenterology
  
  Volume: vol.140, No.4 Pages: 1322-1333
- DOI
  10.1053/j.gastro.2011.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059015, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590973
[Journal Article] Primary gastrointestinal follicular lymphoma involving the duodenal second portion is a distinct entity : a multicenter, retrospective analysis in Japan2011
- Author(s)
  Takata K, Okada H, Ohmiya N, Nakamura S, Kitadai Y, Tari A, Akamatsu T, Kawai H, Tanaka S, Araki H, Yoshida T, Okumura H, Nishisaki H, Sagawa T, Watanabe N, Arima N, Takatsu N, Nakamura M, Yanai S, Kaya H, Morito T, Sato Y, Moriwaki H, Sakamoto C, Niwa Y, Goto H, Chiba T, Matsumoto T, Ennishi D, Kinoshita T, Yoshino T
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1532-1536
- NAID
  10030242267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590973
[Journal Article] Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice.2011
- Author(s)
  Aoki N, Kido M, Iwamoto S, Nishiura H, Maruoka R, Tanaka J, Watanabe T, Okazaki T, Chiba T, Watanabe N.
- Journal Title
  
  Gastroenterology. 140
  
  Pages: 1322-1333
- NAID
  120003001404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Acute airway obstruction in a patient with achalasia2011
- Author(s)
  Miyamoto S, Konda Y, Matsui M, Sawada K, Ikeda K, Watanabe N, Kawanami C, Chiba T
- Journal Title
  
  Intern Med
  
  Volume: 50 Pages: 2333-2336
- NAID
  130001087742
- URL
  https://www.jstage.jst.go.jp/article/internalmedicine/50/20/50_20_2333/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590973
[Journal Article] Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice2011
- Author(s)
  Aoki N, Kido M, Iwamoto S, Nishiura H, Maruoka R, Tanaka J, Watanabe T, Okazaki T, Chiba T, Watanabe N.
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Pages: 1322-1333
- NAID
  120003001404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Dual roles of CagA protein in Helicobacter pylori-induced chronic gastritis in mice2011
- Author(s)
  Kido M, Watanabe N, Aoki N, Iwamoto S, Nishiura H, Maruoka R, Ikeda A, Azuma T, ChibaT
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 412 Pages: 266-272
- DOI
  10.1016/j.bbrc.2011.07.081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590973
[Journal Article] Proinflammatory Th2 cytokines induce production of thymic stromal lymphopoietin in human colonic epithelial cells.2010
- Author(s)
  Tanaka J, Saga K, Kido M, Nishiura H, Akamatsu T, Chiba T, Watanabe N.
- Journal Title
  
  Dig Dis Sci. 55
  
  Pages: 1896-1904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses2010
- Author(s)
  Kido M, Tanaka J, Aoki N, Iwamoto S, Nishiura H, Chiba T, Watanabe N
- Journal Title
  
  Infection and Immunity 78
  
  Pages: 108-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Analysis of Humoral Immune Response in Experimental Autoimmune Pancreatitis in Mice.2010
- Author(s)
  Asada M, Nishio A, Akamatsu T, Tanaka J, Saga K, Kido M, Watanabe N, Uchida K, Fukui T, Okazaki K, Chiba T.
- Journal Title
  
  Pancreas. 39
  
  Pages: 224-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of forkhead box P3+ regulatory T cells in human thymus.2010
- Author(s)
  Hanabuchi S, Ito T, Park WR, Watanabe N, Shaw JL Roman E, Arima K, Wang YH, VooKS, Cao W, Liu YJ.
- Journal Title
  
  J Immunol. 184
  
  Pages: 2999-3007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of forkhead box P3+ regulatory T cells in human thymus2010
- Author(s)
  Hanabuchi S, Ito T, Park WR, Watanabe N, Shaw JL Roman E, Arima K, Wang YH, VooKS, Cao W, Liu YJ
- Journal Title
  
  Journal of Immunology 184
  
  Pages: 2999-3007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses.2010
- Author(s)
  Kido M, Tanaka J, Aoki N, Iwamoto S, Nishiura H, Chiba T, Watanabe N.
- Journal Title
  
  Infect Immun. 78
  
  Pages: 108-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Distinct signal codes generate dendritic cell functional plasticity.2010
- Author(s)
  Arima K, Watanabe N, Hanabuchi S, Chang M, Sun SC, Liu YJ.
- Journal Title
  
  Sci Signal. 3(105)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Distinct signal codes generate dendritic cell functional plasticity2010
- Author(s)
  Arima K, Watanabe N, Hanabuchi S, Chang M, Sun SC, Liu YJ.
- Journal Title
  
  Science Signaling (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Proinflammatory Th2 cytokines induce production of thymic stromal lymphopoietin in human colonic epithelial cells.2010
- Author(s)
  Tanaka J, Saga K, Kido M, Nishiura H, Akamatsu T, Chiba T, Watanabe N
- Journal Title
  
  Dig Dis Sci.
  
  Volume: 55 Pages: 1896-1904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Analysis of humoral immune response in experimental autoimmune pancreatitis inmice2010
- Author(s)
  Asada M, Nishio A, Akamatsu T, Tanaka J, Saga K, Kido M, Watanabe N, Uchida K, Fukui T, Okazaki K, Chiba T
- Journal Title
  
  Pancreas 39
  
  Pages: 224-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2^-polarizing conditions2009
- Author(s)
  Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T
- Journal Title
  
  Clin Exp Allergy 39
  
  Pages: 89-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Human TSLP and TLR3 ligand promote differentiation of Th17 cells with central memory phenotype under Th2- polarizing conditions.2009
- Author(s)
  Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T
- Journal Title
  
  Clin Exp Allergy. 39
  
  Pages: 89-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Human TSLP directly enhances exansion of CD8+T cells2009
- Author(s)
  Akaraatsu T, Watanabe N, Kido M, Saga K, Tanaka J, uzushima K., ishio A, Chiba T
- Journal Title
  
  Clin Exp Immunol 154
  
  Pages: 98-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Tanaka J, Saga K, Nishio A, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1333-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T.
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori ifection2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori immunology and vaccine.2008
- Author(s)
  Vorobjova T, Watanabe T, Chiba T
- Journal Title
  
  Helicobacter 13
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Saga K, Nishio A, Tanaka J, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1333-1343
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori infection.2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N.
- Journal Title
  
  J Gatroenterol Hepatol 23
  
  Pages: 1175-1181
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Human TSLP directly enhances expansion of CD8+ T cells.2008
- Author(s)
  Akamatsu T, Watanabe N, Kido M, Saga K, Tanaka J, Kuzushima K, Nishio A, Chiba T.
- Journal Title
  
  Clin Exp Immunol. 154
  
  Pages: 98-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori in fection.2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling.2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Tanaka J, Saga K, Nishio A, Honjo T, Chiba T.
- Journal Title
  
  Gastroenterology. 135
  
  Pages: 1333-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori immunology and vaccine2008
- Author(s)
  Vorobjova T, Watanabe T, Chiba T
- Journal Title
  
  Helicobacter 13(Suppl 1)
  
  Pages: 18-22
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori infection2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J. Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Data Source
  KAKENHI-PROJECT-20390207
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T.
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling.2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Saga K, Nishio A, Tanaka J, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1333-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses2008
- Author(s)
  Watanabe, N, Kiriya, K, Chiba, T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter- induced gastritis.2007
- Author(s)
  Kiriya K, Watanabe N, et al.
- Journal Title
  
  International Immunology. 19・4
  
  Pages: 435-446
- NAID
  10020110345
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Localized cytomegalovirus reactivation after radiotherapy for high-grade gastric lymphoma.2007
- Author(s)
  Saga K, Watanabe N, et al.
- Journal Title
  
  Gastrointestinal Endoscopy. 65・3
  
  Pages: 545-547
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis.2007
- Author(s)
  Kiriya K, Watanabe N, Chiba T, et al.
- Journal Title
  
  International Immunology 19
  
  Pages: 435-446
- NAID
  10020110345
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Cross-Primed CD8(+) Cytotoxic T cells Induce Severe Helicobacter-associated Gastritis in the Absence of CD4(+) T cells2007
- Author(s)
  Fukui T, Nishio A, Okazaki K, Kasahara K, Saga K, Tanaka J, Uza N, Ueno S, Kido M, Ohashi S, Asada M, Nakase H, Watanabe N, Chiba T
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Cross-priming CD8+ cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4+ T cells.2007
- Author(s)
  Fukui T, Nishio A, Watanabe N, et. al.
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Direct action of thymic stromal lymphopoietin on activated human CD4+ T cells.2007
- Author(s)
  Rochman I, Watanabe N, Arima K, Liu YJ, Leonard WJ.
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 193-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis2007
- Author(s)
  Kiriya K, Watanabe N, Chiba T, et al.
- Journal Title
  
  Int Immunol 19
  
  Pages: 435-446
- NAID
  10020110345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Cross-priming CD8+ cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4+ T cells2007
- Author(s)
  Fukui, T, Nishio, A, Okazaki, K, Kasahara, K, Saga, K, Tanaka, J, Uza, N, Ueno, S, Kido, M, Ohashi, S, Asada, M, Nakase, H, Watanabe, N, Chiba, T
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis.2007
- Author(s)
  Kiriya K, Watanabe N, Nishio A, et al.
- Journal Title
  
  Int Immunol 19
  
  Pages: 435-446
- NAID
  10020110345
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma.2007
- Author(s)
  Iwano M, Watanabe N, et al.
- Journal Title
  
  American Journal Gastroenterology. 101・12
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter- induced gastritis.2007
- Author(s)
  Kiriya K, Watanabe N, et al.
- Journal Title
  
  International Immunology. 19・4
  
  Pages: 435-446
- NAID
  10020110345
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Cross-priming CD8+ cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4+ T cells.2007
- Author(s)
  Fukui T, Nishio A, Okazaki K, Kasahara K, Saga K, Watanabe N, Chiba T, et. al.
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Localized cytomegalovirus reactivation after radiotherapy for high-grade gastric lymphoma.2007
- Author(s)
  Saga K, Watanabe N, et al.
- Journal Title
  
  Gastrointestinal Endoscopy. 65・3
  
  Pages: 545-547
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis2007
- Author(s)
  Kiriya K, Watanabe N, Nishio A, Okazaki K, Kido M, Saga K, Tanaka J, Akamatsu T, Ohashi S, Asada M, Fukui T, Chiba T
- Journal Title
  
  Int Immunol 19
  
  Pages: 435-446
- NAID
  10020110345
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Direct action of thymic stromal lymphopoietin on activated human CD4+ T cells.2007
- Author(s)
  Rochman I, Watanabe N, Arima K, et. al.
- Journal Title
  
  J Immunol 178
  
  Pages: 6720-6724
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Direct action of thymic stromal lymphopoietin on activated human CD4+ T cells.2007
- Author(s)
  Rochman I, Watanabe N, Arima K, Liu YJ, Leonard WJ.
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 193-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Direct action of thymic stromal lymphopoietin on activated human CD4+ T cells2007
- Author(s)
  Rochman, I, Watanabe, N, Arima, K, Liu, YJ, Leonard, WJ
- Journal Title
  
  J. Immunol 178
  
  Pages: 6720-6724
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis2007
- Author(s)
  Kiriya, K, Watanabe, N, Nishio, A, Okazaki, K, Kido, M, Saga, K, Tanaka, J, Akamatsu, T, Ohashi, S, Asada, M, Fukui, T, Chiba, T
- Journal Title
  
  Int. Immunol 19
  
  Pages: 435-446
- NAID
  10020110345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Cross-priming CD8+ cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4+ T cells.2007
- Author(s)
  Fukui T, Nishio A, Okazaki K, Kasahara K, Saga K, Watanabe N, Chiba T, et. al.
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma.2007
- Author(s)
  Iwano M, Watanabe N, et al.
- Journal Title
  
  American Journal Gastroenterology. 101・12
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Human plasmacytoid pre-dendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand(GITRL).2006
- Author(s)
  Hanabuchi S, Watanabe N, Wang YH, et. al.
- Journal Title
  
  Blood 107
  
  Pages: 3617-3623
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma.2006
- Author(s)
  Iwano M, Watanabe N, Matsushima Y, Seno H, Oki K, Sakurai T, Inagaki H, Okazaki K, Chiba T.
- Journal Title
  
  Am J Gastroenterol 101
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Human plasmacytoid pre-dendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).2006
- Author(s)
  Hanabuchi S, Watanabe N, et al.
- Journal Title
  
  Blood. 107・9
  
  Pages: 3617-3623
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma2006
- Author(s)
  Iwano M, Watanabe N, Matsushima Y, Seno H, Oki K, Sakurai T, Inagaki H, Okazaki K, Chiba T
- Journal Title
  
  Am J Gastroenterol 101(12)
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma.2006
- Author(s)
  Iwano M, Watanabe N, Matsushima Y, et. al.
- Journal Title
  
  Am J Gastroenterol 101
  
  Pages: 2878-2883
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Maintenance and polarization of human T_H2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells.2006
- Author(s)
  Wang YH, Ito T, Watanabe N, et. al.
- Journal Title
  
  Immunity 24
  
  Pages: 827-838
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells.2006
- Author(s)
  Wang YH, Watanabe N, et al.
- Journal Title
  
  Immunity. 24・6
  
  Pages: 827-838
- Data Source
  KAKENHI-PROJECT-18015028
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class 2-deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Watanabe N, et. al.
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Human plasmacytoid pre-dendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL)2006
- Author(s)
  Hanabuchi, S, Watanabe, N, Wang, YH, Wang, YH, Ito, T, Shaw, J, Cao, W, Qin, FX, Liu, YJ
- Journal Title
  
  Blood 107
  
  Pages: 3617-3623
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells.2006
- Author(s)
  Wang YH, Watanabe N, et al.
- Journal Title
  
  Immunity. 24・6
  
  Pages: 827-838
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma2006
- Author(s)
  Iwano, M, Watanabe, N, Matsushima, Y, Seno, H, Oki, K, Sakurai, T, Inagaki, H, Okazaki, K, Chiba, T
- Journal Title
  
  Am. J. Gastroenterol 101
  
  Pages: 2878-2883
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Maintenance and polarization of human T_H2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells2006
- Author(s)
  Wang, YH, Ito, T, Wang, YH, Homey, B, Watanabe, N, Marlin, R, Barnes, CJ, McIntyre, BW, Gilliet, M, Kumar, R, Yao, Z, Liu, YJ
- Journal Title
  
  Immunity 24
  
  Pages: 827-838
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Human plasmacytoid pre-dendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).2006
- Author(s)
  Hanabuchi S, Watanabe N, et al.
- Journal Title
  
  Blood. 107・9
  
  Pages: 3617-3623
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice2006
- Author(s)
  Fukui, T, Nishio, A, Okazaki, K, Uza, N, Ueno, S, Kido, M, Inoue, S, Kitamura, H, Kiriya, K, Ohashi, S, Asada, M, Tamaki, H, Matsuura, M, Kawasaki, K, Suzuki, K, Uchida, K, Fukui, H, Nakase, H, Watanabe, N, Chiba, T
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice2006
- Author(s)
  Fukui T, Nishio A, Okazaki K, Uza N, Ueno S, Kido M, Inoue S, Kitamura H, Kiriya K, Ohashi S, Asada M, Tamaki H, Matsuura M, Kawasaki K, Suzuki K, Uchida K, Fukui H, Nakase H, Watanabe N, Chiba T
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] 新たに確立した動物モデルを用いた自己免疫性肝炎の病態解明と新規治療法の開発2013
- Author(s)
  渡部則彦
- Organizer
  難治性疾患等克服研究事業「難治性の肝・胆道疾患に関する調査研究」班平成２５年度第2回総会
- Place of Presentation
  東京ステーションコンファレンス東京
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 自己免疫性肝炎モデルではマウスの系統の違いから同一の免疫機構の破綻によって慢性肝炎から劇症肝炎まで発症する2013
- Author(s)
  渡部則彦、丸岡隆太郎、青木信裕、木戸正博、池田亜希、岩本諭、西浦尚代、千葉勉
- Organizer
  第２4回 The Meeting of Liver and Immunology
- Place of Presentation
  京都国際ホテル　京都
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 自己免疫性肝炎モデルではマウスの系統の違いから同一の免疫機構の破綻によって慢性肝炎から劇症肝炎まで発症する2013
- Author(s)
  渡部則彦、丸岡隆太郎、青木信裕、木戸正博、池田亜希、岩本諭、西浦尚代、千葉勉
- Organizer
  第24回The Meeting of Liver and Immunology
- Place of Presentation
  京都国際ホテル京都
- Year and Date
  2013-09-07
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 慢性から劇症まで多様な病態を呈する自己免疫性肝炎モデルを用いたAIH病態形成機構の解明2013
- Author(s)
  渡部則彦, 池田亜希, 丸岡隆太郎, 西浦尚代, 岩本諭, 青木信裕, 木戸正博, 千葉勉
- Organizer
  第50回日本消化器免疫学会総会
- Place of Presentation
  ホテルグランドヒル市谷東京
- Year and Date
  2013-08-01
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 慢性から劇症まで多様な病態を呈する自己免疫性肝炎(AIH)モデルでの病態解析2013
- Author(s)
  渡部則彦、丸岡隆太郎、池田亜希
- Organizer
  JDDW2013 (第55回日本消化器病学会大会)
- Place of Presentation
  グランドプリンスホテル新高輪　東京
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 慢性から劇症まで多様な病態を呈する自己免疫性肝炎(AIH)モデルでの病態解析2013
- Author(s)
  渡部則彦、丸岡隆太郎、池田亜希
- Organizer
  JDDW 2013 (第55回日本消化器病学会大会)
- Place of Presentation
  グランドプリンスホテル新高輪東京
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新たに確立した動物モデルを用いた自己免疫性肝炎の病態解明と新規治療法の開発難治性疾患等克服研究事業(難治性疾患克服研究事業)「難治性の肝・胆道疾患に関する調査研究」班2013
- Author(s)
  渡部則彦
- Organizer
  平成25年度第2回総会
- Place of Presentation
  東京ステーションコンファレンス
- Year and Date
  2013-12-19
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新たに確立した動物モデルを用いた自己免疫性肝炎の病態解明と新規治療法の開発難治性疾患等克服研究事業(難治性疾患克服研究事業)「難治性の肝・胆道疾患に関する調査研究」班2013
- Author(s)
  渡部則彦
- Organizer
  平成25年度第1回総会
- Place of Presentation
  東京ステーションコンファレンス東京
- Year and Date
  2013-06-27
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新たに確立した動物モデルを用いた自己免疫性肝炎の病態解明と新規治療法の開発2013
- Author(s)
  渡部則彦
- Organizer
  難治性疾患等克服研究事業「難治性の肝・胆道疾患に関する調査研究」班平成２５年度第1回総会
- Place of Presentation
  東京ステーションコンファレンス東京
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Splenectomy overcomes therapeutic insufficiency of corticosteroids and induces prolonged remission2012
- Author(s)
  Maruoka R, Aoki N, Watanabe N
- Organizer
  DDW2012
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-05-21
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 自己免疫性肝炎(AIH)新規モデルマウスの病態から重症・難治性AIHの治療をさぐる2012
- Author(s)
  青木信裕、丸岡隆太郎、渡部則彦
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  ANAクラウンプラザホテル金沢金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 自然発症型自己免疫性肝炎モデルを用いたステロイド治療にかわる新規治療法の探索2012
- Author(s)
  渡部則彦
- Organizer
  第49回日本消化器免疫学会総会
- Place of Presentation
  城山観光ホテル（鹿児島）
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規致死性自己免疫性肝炎(AIH)モデルにおけるAIH劇症化機序の解明2012
- Author(s)
  青木信裕、木戸政博、渡部則彦
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Fatal immune-mediated liver injury is triggered by dysregulated follicular-helper T cells in the spleen of mice―Splenectomy overcomes therapeutic insufficiency of corticosteroids and induces remission2012
- Author(s)
  渡部則彦
- Organizer
  EASL Monothematic Conference: Immune Mediated Liver Injury
- Place of Presentation
  Stratford-Upon-Avon, United Kingdom
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 自然発症型自己免疫性肝炎モデルを用いたステロイド治療にかわる新規治療法の探索2012
- Author(s)
  渡部則彦,丸岡隆太郎、青木信裕
- Organizer
  第49回日本消化器免疫学会総会
- Place of Presentation
  城山観光ホテル鹿児島
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Fatal immune-mediated liver injury is triggered by dysregulated follicular-helper T cells in the spleen of mice―Splenectomy overcomes therapeutic insufficiency of corticosteroids and induces remission2012
- Author(s)
  Watanabe N
- Organizer
  EASL Monothematic Conference : Immune Mediated Liver Injury
- Place of Presentation
  Stratford-Upon-Avon, United Kingdom
- Year and Date
  2012-01-20
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規致死性自己免疫性肝炎(AIH)モデルにおけるAIH劇症化機序の解明2012
- Author(s)
  渡部則彦
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Mechanisms involved in fatal progression of autoimmune hepatitis in mice.2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  UEGW Stockholm 2011
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規自己免疫性肝炎(AIH)モデルにおけるAIH劇症化機構の解明2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第19回日本消化器関連学会週間
- Place of Presentation
  福岡,福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 致死性自己免疫性肝炎マウスモデルの発症における脾臓TFH細胞の関与2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規モデルマウスを用いた自己免疫性肝炎(AIH)発症機序の解明2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第47回日本肝臓病学会総会
- Place of Presentation
  ホテルグランパシフィックLE DAIBA 東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規致死性自己免疫性肝炎(AIH)モデルにおける発症機構の解明と新たな免疫療法の開発2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第48回日本消化器免疫学会総会
- Place of Presentation
  石川, 金沢エクセル東急
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規モデルマウスを用いた自己免疫性肝炎(AIH)発症機序の解明2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第47回日本肝臓病学会総会
- Place of Presentation
  東京, ホテルグランパシフィック LE DAIBA
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規致死性自己免疫性肝炎(AIH)モデルにおける発症機構の解明と新たな免疫療法の開発2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第48回日本消化器免疫学会総会
- Place of Presentation
  金沢エクセル東急石川
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Mechanisms involved in fatal progression of autoimmune hepatitis in mice2011
- Author(s)
  Aoki N, Watanabe N
- Organizer
  AASLD The Liver Meeting 2011
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 新規自己免疫性肝炎(AIH)モデルにおけるAIH劇症化機構の解明2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第19回日本消化器関連学会週間
- Place of Presentation
  福岡国際会議場福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Mechanisms involved in fatal progression of autoimmune hepatitis in mice2011
- Author(s)
  Aoki N, Watanabe N
- Organizer
  UEGW Stockholm 2011
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] 致死性自己免疫性肝炎マウスモデルの発症における脾臓TFH細胞の関与2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉, 幕張メッセ
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] Mechanisms involved in fatal progression of autoimmune hepatitis in mice.2011
- Author(s)
  青木信裕、渡部則彦
- Organizer
  AASLD The Liver Meeting 2011
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23590973
[Presentation] TNF-α but not IFN-γ plays a critical role in the development of fatal autoimmune hepatitis2010
- Author(s)
  Watanabe N., Iwamoto S, Kido M, Aoki N, Nishiura H, Chiba T.
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Centre convencions intemacional Barcelona, Barcelona, Spain
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Differential roles of PD-1 mediated signaling in inflammation in mouse models of Helicobacter infection and autoimmune gastritis.2010
- Author(s)
  木戸政博, 岩本諭, 青木信裕, 西浦尚代, 田中淳也, 千葉勉, 渡部則彦
- Organizer
  第16回日本ヘリコバクター学会学術集会
- Place of Presentation
  京都大学医学部芝蘭会館
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Regulatory T cells and PD-1-mediated signaling in AIH2010
- Author(s)
  Watanabe N
- Organizer
  International Forum of the 96^<th> Annual Meeting of the Japanese Society of Gastroenterology
- Place of Presentation
  新潟県新潟市朱鷺メッセ
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Regulatory T cells and PD-1-mediated signaling in AIH.2010
- Author(s)
  渡部則彦
- Organizer
  International Forum of the 96^<th> Annual Meeting of the Japanese Society of Gastroenterology
- Place of Presentation
  新潟県新潟市朱鷺メッセ
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Differential roles of PD-1 mediated signaling in inflammation in mouse models of Helicobacter infection and autoimmune gastritis2010
- Author(s)
  木戸政博, 岩本諭, 青木信裕, 西浦尚代, 田中淳也, 千葉勉, 渡部則彦
- Organizer
  第16回日本ヘリコバクター学会学術集会
- Place of Presentation
  京都大学医学部芝蘭会館
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] 新規自己免疫性肝炎モデルの免疫病態解析からみた新たな治療戦略2010
- Author(s)
  渡部則彦、岩本諭、木戸政博
- Organizer
  第18回日本消化器関連学会週間
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] CCR6-CCL20 axis dependent direct migration of splenic CD4+ T cells is indispensable for the induction of fatal autoimmune hepatitis.2010
- Author(s)
  Aoki N, Kido M, Iwamoto S, Nishiura H, Chiba T, Watanabe N.
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Centre convencions intemacional Barcelona, Barcelona, Spain
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] 新規自己免疫性肝炎(AIH)モデルによるAIH発症機序の解析2010
- Author(s)
  青木信裕, 木戸政博, 岩本諭, 西浦尚代, 丸岡隆太郎, 千葉勉, 渡部則彦
- Organizer
  第93回日本消化器病学会近畿支部例会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Mechanisms involved in the development of fatal autoimmune hepatitis2010
- Author(s)
  Watanabe N, Kido M, Aoki N, Iwamoto S, Nishiura H, Okazaki T, Honjo T, Chiba T
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Differential roles of IFN-γ and TNF-α in the development of fatal autoimmune hepatitis2009
- Author(s)
  岩本諭, 渡部則彦, 千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] 新規自己免疫性肝炎動物モデルにおける免疫担当細胞からみたその病態と治療の可能性2009
- Author(s)
  渡部則彦, 木戸政博, 千葉勉
- Organizer
  第51回日本消化器病学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Regulatory roles of PD1 mediated signaling in the development of Helicobacter-induced gastritis and autoimmune gastritis2009
- Author(s)
  青木信裕、渡部則彦、千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Proinflammatory Th2 cytokines induce production of thymic stromal lymphopoietin in human colonic epithelial cells.2009
- Author(s)
  田中淳也、渡部則彦、千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] TSLP regulates autoantibody production and inflammation in mouse models of autoimmune gastritis.2009
- Author(s)
  西浦尚代、渡部則彦、千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Helicobacter promote gastric epithelial cells to produce TSLP and induce DC-mediated inflammatory Th2 responses.2009
- Author(s)
  Watanabe N, Kido M, Tanaka J, Chiba T.
- Organizer
  米国消化器病週間(DDW)2009会議
- Place of Presentation
  Mccormick Place Convention Center, Chicago, USA.
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Helicobacter promote gastric epithelial cells to produce TSLP and induce DC-me diated inflammatory Th2 responses2009
- Author(s)
  Watanabe N, Kido M, Tanaka J, Chiba T
- Organizer
  Digestive Disease Week and the 110^<th> Annual Meeting of the AGA institute
- Place of Presentation
  Mccormick Place Convention Center, Chicago, USA
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Role of Peyer's patches in H. pylori immunity.2009
- Author(s)
  渡部則彦
- Organizer
  XXIst International Workshop on Helicobacter and related bacteria in chronic digestive inflammation and gastric cancer
- Place of Presentation
  Fundacao Eng.Antonio de Almeida, Porto, Portugal
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] TSLP regulates autoantibody production and inflammation in mouse models of autoimmune gastritis2009
- Author(s)
  西浦尚代, 渡部則彦, 千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Role of Peyer patches in H. pylori immunity2009
- Author(s)
  渡部則彦
- Organizer
  XXIst International Workshop on Helicobacter and related bacteria in chronic digestive inflammation and gastric cancer
- Place of Presentation
  Fundacao Eng. Antoniode Almeida, Porto, Portugal
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] 消化管 follicular lymphoma の診断と治療-その戦略2009
- Author(s)
  渡部則彦, 近藤忠一, 千葉勉
- Organizer
  第51回日本消化器病学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Essential role of CD8+ T cells in development of fatal autoimmune hepatitis2009
- Author(s)
  木戸政博, 渡部則彦, 千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Proinflammatory Th2 cytokines induce production of thymic stromal lympho-poietin in human colonic epithelial cells2009
- Author(s)
  田中淳也, 渡部則彦, 千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Regulatory roles of PD1 mediated signaling in the development of helicobacter-induced gastritis and autoimmune gastritis2009
- Author(s)
  青木信裕, 渡部則彦, 千葉勉
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Helicobacter pylori感染に対する宿主免疫応答でのTSLPの役割2008
- Author(s)
  木戸政博、渡部則彦、千葉勉
- Organizer
  第45回日本消化器免疫学会総会
- Place of Presentation
  京都市京都メルパルク
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Helicobacter pylori感染に対する宿主免疫応答でのTSLPの役割2008
- Author(s)
  木戸政博、渡部則彦、千葉勉
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Essential role of dendritic cells in Peyer's patches in the development of Helicobacter-induced chronic gastritis2008
- Author(s)
  渡部則彦, 木戸政博, 千葉勉
- Organizer
  国際樹状細胞会議2008
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] The role of TSLP in the host immune response for Helicobacter pylori2008
- Author(s)
  Kido, M, Watanabe, N, Chiba, T
- Organizer
  The 94th Annual Meeting of the Japanease of Gastroenterology
- Place of Presentation
  Hakata, Japan
- Year and Date
  2008-05-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] The role. fo TSLP in the host immune response for Helicobacter pylori.2008
- Author(s)
  Kido M, Watanabe N, Chiba T.
- Organizer
  The 94th Annual Meeting of the Japananese Society of Gatstroenterology.
- Place of Presentation
  Hakata, Japan
- Year and Date
  2008-05-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Helicobacter pylori感染に対する宿主免疫応答でのTSLPの役割2008
- Author(s)
  木戸政博、渡部則彦、千葉勉
- Organizer
  第14回日本ヘリコバクター学会学術集会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20390207
[Presentation] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis.2007
- Author(s)
  Watanabe N, Kiriya K, Nishio A, Kido M, Saga K, Tanaka K, Chiba T, et. al.
- Organizer
  Digestive Disease Week 2007
- Place of Presentation
  Washington DC, USA
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Human TSLP enhances TLR-ligand-mediated IL-23 production by myeloid dendritic cells and has a potential to induce Th17 inflammatory responses.2007
- Author(s)
  Tanaka J, Watanabe N, Kido M, et. al.
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy.
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Helicobacter triggers gastric epithelial cells to produce TSLP which induces DC-mediated inflammatory Th2 responses.2007
- Author(s)
  Kido M, Watanabe N, Tanaka J, Akamatsu T, Nishio A, Chiba T, et. al.
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy
- Place of Presentation
  Shinagawa, Tokyo
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18015028
[Presentation] Human TSLP enhances TLR-ligand-mediated IL-23 production by myeloid dendritic cells and has a potential to induce Th17 inflammatory responses.2007
- Author(s)
  Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Chiba T, et. al.
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy
- Place of Presentation
  Shinagawa, Tokyo
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Helicobacter triggers gastric epithelial cells to produce TSLP which induces DC-mediated inflammatory Th2 responses.2007
- Author(s)
  Kido M, Watanabe N, Tanaka J, et. al.
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy.
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Human TSLP enhances TLR-ligand-mediated IL-23 production by myeloid dendriticcells and has a potential to induce Th17 inflammatory responses.2007
- Author(s)
  Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Chiba T, et. al.
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy
- Place of Presentation
  Shinagawa, Tokyo
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18015028
[Presentation] Human TSLP enhances TLR-ligand-mediated IL-23 production by myeloid dendritic cells and has a potential to induce Th17 inflammatory responses2007
- Author(s)
  Tanaka, J, Watanabe, N, Kido, M,Saga, K, Akamatsu, T, Nishio, A, Chiba, T
- Organizer
  The 37 thAnnual Meeting of the Japanese Society for Immnologoy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Helicobacter triggers gastric epithelial cells to produce TSLP which induces DC-mediated inflammatory Th2 responses2007
- Author(s)
  Kido, M, Watanabe, N, Tanaka, J, Akamatsu, T, Nishio, A, Chiba, T
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-11-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Helicobacter triggers gastric epithelial cells to produce TSLP which induces DC-mediated inflammatory Th2 responses.2007
- Author(s)
  Kido M, Watanabe N, Tanaka J, Akamatsu T, Nishio A, Chiba T, et. al.
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immnologoy
- Place of Presentation
  Shinagawa, Tokyo
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18590679
[Presentation] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis.2007
- Author(s)
  Watanabe N, Kiriya K, Nishio A, Kido M, Saga K, Tanaka K, Chiba T, et. al.
- Organizer
  Digestive Disease Week 2007
- Place of Presentation
  Washington DC, USA
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-18015028

1. CHIBA Tsutomu (30188487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
2. WATANABE Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
3. HONDA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. EGAWA Gyohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 渡辺武

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 中島沙恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 宮地良樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 稲葉カヨ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岡崎拓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Norihiko 渡部 則彦

WATANABE Norihiko 渡部 則彦

Research Projects

Research Products

Co-Researchers

Immune mechanisms involved in the development of fatal autoimmune hepatitis in micePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Immunologic response to Helicobacter involved in the development of chronic gastritisPrincipal Investigator

Principal Investigator

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Research Institution

ヒト樹状細胞活性化因子TSLPを用いた新規腫瘍特異的免疫療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism for inflammation-associated gastrointestinal carcinogenesis.

Principal Investigator

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Research Institution

Elucidation of pathaphysiological roles of human thymic stromal lymphopoietin (TSLP) in inflammatory bowel diseasesPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

[Book] H.pylori infection-The route from inflammation to cancer. In Sansonetti P, ed, Infection Biology Handbook Series. Bacterial Virulence. Basic principles, models and global approaches.2010

Author(s)

Publisher

Data Source

[Book] H.pylori infection .The route from inflammation to cancer. In Sansonetti P, ed, Infection Biology Handbook Series. Bacterial Virulence.2010

Author(s)

Publisher

Data Source

[Journal Article] Progression of autoimmune hepatitis is mediated by IL-18-producing dendritic cells and hepatic CXCL9 expression in mice.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] TNF-αis essential in the induction of fatal autoimmune hepatitis in mice through upregulation of hepatic CCL20 expression2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Splenectomy prolongs the effects of corticosteroids in mouse models of autoimmune hepatitis2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Interleukin-21 and TNF-αare critical for the development of autoimmune gastritis in mice2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling.2012

Author(s)

Journal Title

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Data Source

[Journal Article] Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient Mice.2012

Author(s)

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DOI

Data Source

[Journal Article] Long-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori : a multicentre cohort follow-up study of 420 patients in Japan2012

Author(s)

Journal Title

DOI

Watanabe Norihiko 渡部則彦

WATANABE Norihiko 渡部則彦