Fujishiro Midori 藤城緑

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FUJISHIRO Midori 藤城緑

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Researcher Number	50420211
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 准教授(任期制)
Affiliation (based on the past Project Information) *help	2017 – 2022: 日本大学, 医学部, 助教 2016: 東京大学, 附属病院, 助教 2009 – 2015: The University of Tokyo, 医学部附属病院, 助教 2008: The University of Tokyo, 医学部・附属病院, 助教 2007: The University of Tokyo, University Hospital, Assistant professor … More 2006: 東京大学, 医学部附属病院, 助手 2005: 東京大学, 医学部付属病院, 医員 2005: The University of Tokyo, Hospital, Medical Staff, 医学部附属病院, 医員 2005: 東京大学, 医学部附属病院内科, 医員 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Metabolomics / Biological Sciences
Keywords	Principal Investigator インスリン抵抗性 / 糖尿病 / 糖質代謝異常 / エネルギー / 蛋白質 / 細胞・組織 / シグナル伝達 / 生活習慣病 / キサンチン酸化還元酵素 / 2型糖尿病 / インスリン受容体 / 高グルコース刺激 … More Except Principal Investigator … More インスリン / 糖尿病 / 代謝 / Pin1 / グルコーストランスポーター / 糖代謝 / インスリン分泌 / TFG / シグナル伝達 / insulin resistance / Diabetes mellitus / insulin / Akt / AMPK / インスリン抵抗性 / 遺伝子改変 / 膵β細胞 / オミックス / TCAサイクル / 解糖系 / トランスクリプトーム / メタボローム / 膵島 / メタボシックシンドローム / LUBAC / 肝細胞 / 肥満 / メタボリックシンドローム / プロリン異性化酵素 / 糖・脂質代謝 / ＴＦＧ / IRS-1 / glucose transporter / proteomics / 糖取り込み / プロテオミクス / resistin / 糖輸送担体 / 運動 / レジスチン / 糖の取り込み / 脂肪細胞 / プロテオーム Less

Elucidation of roles of XOR on impairment of insulin secretion and action in type 2 diabetes with obesityPrincipal Investigator
- Principal Investigator
  
  FUJISHIRO Midori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nihon University
Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nihon University
Roles of trk-fused gene product protein
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Roles of Pin1 and PAR 14 on the metabolic regulations
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Elucidation of mechanisms by which exercise improves inflammation induced by type 2 diabetesPrincipal Investigator
- Principal Investigator
  
  FUJISHIRO Midori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Investigation of the role of insulin signaling molecules on development of hepatocytes into hepatocytes with fatty changesPrincipal Investigator
- Principal Investigator
  
  FUJISHIRO Midori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Clarification of the role of annexin on glucose transportPrincipal Investigator
- Principal Investigator
  
  FUJISHIRO Midori
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
mTOR/Raptor、Rictorを介した代謝調節とインスリン感受性への関与Principal Investigator
- Principal Investigator
  
  藤城緑
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Elucidation of the molecular mechanisms underlying metabolic disorders using protemomics analysis
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
プロテオーム解析によるインスリン感受性調節機構の解明と新規治療ターゲットの発見
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
小胞構成蛋白の網羅的解析による糖輸送担体の制御機構および糖尿病における障害の解明
- Principal Investigator
  
  浅野知一郎
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Elucidation of the molecular mechanisms underlying insulin and exercise-induced effects on metabolism and vascular cells
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

[Journal Article] A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness,2023
- Author(s)
  Tanaka A, Kosuda M, Yamana M, Furukawa A, Nagasawa A, Fujishiro M, Kohno G, Ishihara H.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 5654-5654
- DOI
  10.1038/s41598-023-32589-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08918, KAKENHI-PROJECT-20K11590
[Journal Article] Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice2019
- Author(s)
  Inoue Masa-Ki、Matsunaga Yasuka、Nakatsu Yusuke、Yamamotoya Takeshi、Ueda Koji、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Iwashita Misaki、Sano Tomomi、Nishimura Fusanori、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Asano Tomoichiro
- Journal Title
  
  Diabetology & Metabolic Syndrome
  
  Volume: 11 Issue: 1 Pages: 57-57
- DOI
  10.1186/s13098-019-0454-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150
[Journal Article] Two adult siblings with myotonic dystrophy type 1 with different phenotypes presenting with chronic respiratory insufficiency and sleep apnea syndrome2019
- Author(s)
  3.Kohno G, Ogawa K, Kushimoto M, Tanaka S, Ikeda J, Nishizawa T, Mitsuke K, Nakayama T, Suzuki Y, Ishihara H, Fujishiro M.
- Journal Title
  
  Front Neurol
  
  Volume: 10 Pages: 681-681
- DOI
  10.3389/fneur.2019.00681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09850
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-13432-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion2017
- Author(s)
  Nakatsu Y, Mori K, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mitsuzaki-Miyoshi K, Sakoda H, Fujishiro M, Yamaguchi S, Kushiyama A, Ono H, Ishihara H, Asano T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 28 Pages: 11886-11895
- DOI
  10.1074/jbc.m117.780726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] Reduced SHARPIN and LUBAC Formation May Contribute to CCl4- or Acetaminophen-Induced Liver Cirrhosis in Mice.2017
- Author(s)
  Yamamotoya, T., Nakatsu, Y., Matsunaga, Y., Fukushima, T., Yamazaki, H., Kaneko, S., Fujishiro, M., Kikuchi, T., Kushiyama, A., Tokunaga, F., Asano, T., Sakoda, H.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 18 Pages: 326-326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Involvement of Resistin-like molecule beta in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice2016
- Author(s)
  Okubo H., Kushiyama, A., Sakoda, H., Nakatsu, Y., Iizuka, M., Taki, N., Fujishiro, M., Fukushima, T., Kamata, H., Nagamachi, A., Inaba, T., Nishimura, F., Katagiri, H., Asahara, T., Yoshida, Y., Chonan, O., Encinas, J., and Asano, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 20157-20157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.2016
- Author(s)
  Nakatsu, Y., Matsunaga, Y., Yamamotoya, T., Ueda, K., Inoue, Y., Mori, K., Sakoda, H., Fujishiro, M., Ono, H., Kushiyama, A., and Asano, T.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Role of uric acid metabolism-related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and non-alcoholic steatohepatitis2016
- Author(s)
  Kushiyama, A., Nakatasu, Y., Matsunaga, Y., Yamamotoya, T., Mori, K., Ueda, K., Sakoda, H., Fujishiro, M., Ono, H., and Asano, T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2016 Pages: 8603164-8603164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Tsuchiya, Y., Kamata, H., Nishimutra, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Endocrinol Metab.
  
  Volume: 309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu, Y., Seno, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Katasako, A., Mori, K., Matsunaga, Y., Fukushima, T., Kanaoka, R., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Tsuchiya, Y., Kamata, H., Nishimutra, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Endocrinol Metab.
  
  Volume: 309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 50-50
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Toshiaki Fukushima, Yasuka Matsunaga, Haruya Ohno, Masayasu Yoneda, Hideaki Kamata, Takanori Shinjo, Misaki Iwashita, Fusanori Nishimura, and Tomoichiro Asano
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol.
  
  Volume: 308 Issue: 2 Pages: 151-158
- DOI
  10.1152/ajpgi.00198.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406
[Journal Article] Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.2015
- Author(s)
  Qiang, S., Nakatsu, Y., Seno, Y., Fujishiro, M., Sakoda, H., Kushiyama, A., Mori, K., Matsunaga, Y., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 104-104
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu, Y., Seno, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Katasako, A., Mori, K., Matsunaga, Y., Fukushima, T., Kanaoka, R., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Prolyl Isomerase Pin1 Negatively Regulates AMPK by Associating with the CBS Domain in the γ-subunit.2015
- Author(s)
  Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, T., Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 24255-24266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Okubo, H., Nakatsu, Y., Sakoda, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Matsunaga, Y., Ohno, H., Yoneda, M., Kamata, H., Shinjo, T., Iwashita, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga, Y., Nakatsu, Y., Fukushima, T., Okubo, H., Iwashita, M., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kushiyama, A., Takahashi, S., Tsuchiya, Y., Kamata, H., Tokunaga, F., Iwai, K., and Asano, T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 12 Pages: 125380-125380
- NAID
  120005745641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.2015
- Author(s)
  Qiang, S., Nakatsu, Y., Seno, Y., Fujishiro, M., Sakoda, H., Kushiyama, A., Mori, K., Matsunaga, Y., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 104-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga, Y., Nakatsu, Y., Fukushima, T., Okubo, H., Iwashita, M., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kushiyama, A., Takahashi, S., Tsuchiya, Y., Kamata, H., Tokunaga, F., Iwai, K., and Asano, T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 12 Pages: 125380-125380
- NAID
  120005745641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Prolyl Isomerase Pin1 Negatively Regulates AMPK by Associating with the CBS Domain in the γ-subunit.2015
- Author(s)
  Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, T., Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 24255-24266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka, R., Kushiyama, A., Seno, Y., Nakatsu, Y., Matsunaga, Y., Fukushima, T., Tsuchiya, Y., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kamata, H., Matsubara, A., and Asano, T.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka, R., Kushiyama, A., Seno, Y., Nakatsu, Y., Matsunaga, Y., Fukushima, T., Tsuchiya, Y., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kamata, H., Matsubara, A., and Asano, T.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 50-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Okubo, H., Nakatsu, Y., Sakoda, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Matsunaga, Y., Ohno, H., Yoneda, M., Kamata, H., Shinjo, T., Iwashita, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Detection of novel visible-light region absorbance peaks in the urine after alkalization in patients with alkaptonuria.2014
- Author(s)
  Tokuhara Y, Shukuya K, Tanaka M, Mouri M, Ohkawa R, Fujishiro M, Takahashi T, Okubo S, Yokota H, Kurano M, Ikeda H, Yamaguchi S, Inagaki S, Ishige-Wada M, Usui H, Yatomi Y, Shimosawa T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e86606-e86606
- DOI
  10.1371/journal.pone.0086606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591314
[Journal Article] Lung abscess without sepsis in a patient with diabetes with refractory episodes of spontaneous hypoglycemia: a case report and review of the literature.2014
- Author(s)
  Toda G, Fujishiro M, Yamada T, Shojima N, Sakoda H, Suzuki R, Yamauchi T, Ueki K, Kadowaki T.
- Journal Title
  
  J Med Case Rep
  
  Volume: 8 Issue: 1 Pages: 51-51
- DOI
  10.1186/1752-1947-8-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-25461373
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice2013
- Author(s)
  Iwashita M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima T, Kumamoto S, Shinjo T, Kamata H, Nishimura F, Asano T
- Journal Title
  
  Adipocyte
  
  Volume: 2(1) Issue: 1 Pages: 28-32
- DOI
  10.4161/adip.21837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24792328
[Journal Article] Integrator complex plays anessential role inadipose differentiation2013
- Author(s)
  Otani Y, Nakatsu Y, Sakoda H, Fukushima T, Fujishiro M, Kushiyama A, Okubo H, Tsuchiya Y, Ohno H, Takahashi S, Nishimura F, Kamata H, Katagiri H, Asano T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 434 Issue: 2 Pages: 197-202
- DOI
  10.1016/j.bbrc.2013.03.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928
[Journal Article] Lactobacillus casei strain Shirota protects against non-alcoholic steatohepatitis development in a rodent model2013
- Author(s)
  Okubo H, Sakoda H, Kushiyama A, Fujishiro M, Nakatsu Y, Fukushima T, Matsunaga Y, Kamata H, Asahara T, Yoshida Y, Chonan O, Iwashita M, Nishimura F, Asano T
- Journal Title
  
  American Journal Physiolgy-Gastrointestinal and Liver Physiogy
  
  Volume: 305 Issue: 12 Pages: 911-918
- DOI
  10.1152/ajpgi.00225.2013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Par14 associates with IRS-1, thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.2013
- Author(s)
  Zhang J, Nakatsu Y, Sinjo T, Guo Y, Sakoda H, Yamamotoya T, Otani Y, Okubo H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T.
- Journal Title
  
  Ｊournal of Biological Chemistry
  
  Volume: 288 Issue: 28 Pages: 20692-20701
- DOI
  10.1074/jbc.m113.485730
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Resistin-Like Molecule β Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development.2013
- Author(s)
  Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 33 Issue: 8 Pages: 1986-1993
- DOI
  10.1161/atvbaha.113.301546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23591099, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PUBLICLY-25111705, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-25670762
[Journal Article] Xanthine oxidoreductase is involved in macrophage foam cell formation and athe rosclerosis development2012
- Author(s)
  Kushiyama A, Fujishiro M, et al
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32(2) Pages: 291-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790847
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes2012
- Author(s)
  Iwashita M, Fujishiro M, et al
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790847
[Journal Article] LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8.2012
- Author(s)
  Kikuchi T, Zhang J, Sakoda H, Koketsu Y, Fujishiro M, Kushiyama A, Nakatsu Y, Kamata H, Inoki K, Takahashi S, Kurihara H, Hideki K, Oka Y, Asano T
- Journal Title
  
  Obesity Research and Clinical Practice
  
  Volume: 6 Issue: 3 Pages: 175-262
- DOI
  10.1016/j.orcp.2011.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-23370062
[Journal Article] Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and atherosclerosis development2012
- Author(s)
  Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata H, Kawazu S, Higashi Y, Kurihara H, Asano T.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Issue: 2 Pages: 291-298
- DOI
  10.1161/atvbaha.111.234559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390238, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24790928
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.2012
- Author(s)
  Iwashita M, Sakoda H, Kushiyama A, Fujishiro M, Ohno H, Nakatsu Y, Fukushima T, Kumamoto S, Tsuchiya Y, Kikuchi T, Kurihara H, Akazawa H, Komuro I, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  American Journal of Physiology - Endocrinology and Metabolism
  
  Volume: 302 Issue: 3 Pages: 286-296
- DOI
  10.1152/ajpendo.00324.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23390213, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24790928
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent model2012
- Author(s)
  Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuchi T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 53 Pages: 44526-44535
- DOI
  10.1074/jbc.m112.397133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24790928
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity2011
- Author(s)
  Ohno H, Fujishiro M, et al
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 300(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790847
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis2011
- Author(s)
  Nakatsu Y, Sakoda H, Kushiyama A, Zhang J, Ono H, Fujishiro M, Kikuchi T, Fukushima T, Yoneda M, Ohno H, Horike N, Kanna M, Tsuchiya Y, Kamata H, Nishimura F, Isobe T, Ogihara T, Katagiri H, Oka Y, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 23 Pages: 20812-20822
- DOI
  10.1074/jbc.m110.206904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-22248030, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-22790869, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity2011
- Author(s)
  Ohno H, Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Otani Y, Okubo H, Yoneda M, Fukushima T, Kamata H, Nishimura F, Kurihara H, Katagiri H, Oka Y, Asano T
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 300(5) Issue: 5 Pages: 1047-54
- DOI
  10.1152/ajpcell.00416.2010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-22790869, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-23791047
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.2010
- Author(s)
  Cui X, Kushiyama A, Yoneda M, Nakatsu Y, Guo Y, Zhang J, Ono H, Kanna M, Sakoda H, Ono H, Kikuchi T, Fujishiro M, Shiomi M, Kamata H, Kurihara H, Kikuchi M, Kawazu S, Nishimura F, Asano T.
- Journal Title
  
  Diabetes Res Clin Pract. 87(1)
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy2009
- Author(s)
  Cui X, Kushiyama A, Yoneda M, Fujishiro M, et al.
- Journal Title
  
  Diabetes Res Clin Pract. 87
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Regulation of gut-derived resistin-like molecule beta expression by nutri ents.2008
- Author(s)
  Fujio J, Kushiyama A, Sakoda H, Fujishiro M, et. al.
- Journal Title
  
  Diabetes Res Clin Pract. 79
  
  Pages: 2-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790613
[Journal Article] Regulation of gut-derived resistin-like molecule beta expression by nutrients.2008
- Author(s)
  Fujio J, Kushiyama A, Sakoda H, Fujishiro M, Ogihara T, Fukushima Y, Anai M, Horike N, Kamata H, Uchijima Y, Kurihara H, Asano T
- Journal Title
  
  Diabetes Res Clin Pract. 79(1)
  
  Pages: 2-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] AMP-ctivated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver2008
- Author(s)
  Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, et.al.
- Journal Title
  
  J Biol Chem 223
  
  Pages: 33902-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells2008
- Author(s)
  Egawa M, Kamata H, Kushiyama A, Sakoda H, Fujishiro M, et.al.
- Journal Title
  
  Placenta 29
  
  Pages: 1003-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells.2008
- Author(s)
  Egawa M, Kamata H, Kushiyama A, Sakoda H, Fujishiro M, Horike N, Yoneda M, Nakatsu Y, Ying G, Jun Z, Tsuchiya Y, Takata K, Kurihara H, Asano T.
- Journal Title
  
  Placenta 29(12)
  
  Pages: 1003-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.2008
- Author(s)
  Koketsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima Y, Ono H, Anai M, Kikuchi T, Fukuda T, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T.
- Journal Title
  
  Am J Physiol Endocrinol Metab. 294(4)
  
  Pages: 719-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice2008
- Author(s)
  Koketsu Y, Sakoda H, Fujishiro M, et.al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.2008
- Author(s)
  Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T
- Journal Title
  
  J Biol Chem. 283(49)
  
  Pages: 33902-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790638
[Journal Article] Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.2008
- Author(s)
  Koketsu Y, Sakoda H, Fujishiro M, et. al.
- Journal Title
  
  Am J Physiol Endocrinol Metab. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790613
[Journal Article] Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.2007
- Author(s)
  Ono H, Sakoda H, Fujishiro M, et. al.
- Journal Title
  
  Am J Physiol Cell Physiol. 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790613
[Journal Article] Physiological significance of resistin and resistin-like molecules in the inflammatory process and insulin resistance.2006
- Author(s)
  Asano, T., Sakoda, H., Fujishiro, M., et al.
- Journal Title
  
  Current Diabetes Reviews 2
  
  Pages: 449-454
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390262
[Journal Article] Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression.2006
- Author(s)
  Viana AY, Fujishiro M, et al.
- Journal Title
  
  Diabetes Res Clin Pract 73・2
  
  Pages: 135-142
- Data Source
  KAKENHI-PROJECT-18790613
[Journal Article] Physiological significance of resistin and resistin-like molecules in the imflammatory process and insulin resistance2006
- Author(s)
  Asano, T., Sakoda, H., Fujishiro, M., et al.
- Journal Title
  
  Current Diabetes Reviews 2
  
  Pages: 449-454
- Data Source
  KAKENHI-PROJECT-18390271
[Journal Article] Glycogen debranching enzyme association with β-subunit enhances AMP-activated protein kinase activity2005
- Author(s)
  Sakoda, H., Fujishiro, M., Asano, T., et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 289(3)
- Data Source
  KAKENHI-PROJECT-17659273
[Journal Article] Glycogen debranching enzyme association with β-subunit enhances AMP-activated protein kinase activity2005
- Author(s)
  Sakoda, H., Fujishiro, M., Asano, T., et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 289(3)
- Data Source
  KAKENHI-PROJECT-17019010
[Journal Article] Glycogen debranching enzyme association with β-subunit enhances AMP-activated protein kinase activity2005
- Author(s)
  Sakoda, H., Fujishiro, M., Asano, T., et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 289(3)
- Data Source
  KAKENHI-PROJECT-16390262
[Journal Article] LST8levelcontrolsbasalp70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8
- Author(s)
  Kikuchi T, Fujishiro M, et al
- Journal Title
  
  Obesity Research & Clinical Practice
  
  Volume: (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790847
[Presentation] 異なる耐糖能障害の形成を呈した筋緊張性ジストロフィー1型の兄妹例2019
- Author(s)
  河野玄太、藤城緑、久志本優、池田迅、田中翔、岡本真由美、江頭富士子、小川克彦、鈴木裕、中山智祥、石原寿光
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] MIN6細胞における解糖系中間体によるインスリン産生制御2019
- Author(s)
  山名碧、藤城緑、藤城緑、山口賢、江頭富士子、藤城緑、渡邉健太郎、石原寿光
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] 性ホルモン結合グロブリン（SHBG）による脂肪量減少効果と抗炎症効果2016
- Author(s)
  山崎広貴、櫛山暁史、迫田秀之、藤城緑、山本屋武、菊池貴子、金子直、浅野知一郎
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] Trk-fused gene（TFG）の膵β細胞における役割の解明2016
- Author(s)
  山本屋武、中津祐介、迫田秀之、藤城緑、山崎広貴、菊池貴子、浅野知一郎、櫛山暁史
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] プロリン異性化酵素Pin1を介した膵β細胞調節機構の解明2016
- Author(s)
  中津祐介、森馨一、松永泰花、山本屋武、藤城緑、石原寿光、浅野知一郎
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 肝外キサンチンオキシダーゼのインスリン抵抗性への関与2016
- Author(s)
  櫛山暁史、菊池貴子、山崎広貴、迫田秀之、藤城緑、浅野知一郎、岩本安彦
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2015
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山本屋武、山崎広貴、中津祐介、浅野知一郎、河津捷二
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討2015
- Author(s)
  松永泰花、中津祐介、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、新城尊徳、岩下未咲、西村英紀、小野啓、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] SGLT2阻害薬ルセオグリフロジンによる非アルコール性脂肪性肝炎の改善作用2015
- Author(s)
  藤城緑、中津祐介、迫田秀之、櫛山暁史、松永泰花、山本屋武、鎌田英明、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 肝臓におけるLUBAC(linear ubiquitin assembly complex)活性低下はAkt-mTOR経路の亢進および肝での炎症を惹起する2015
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、金子直、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 高脂肪食負荷による近位筋優位遺伝性運動感覚ニューロパチー原因遺伝子TFGの発現低下とその病的意義2015
- Author(s)
  浅野知一郎、松永泰花、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、小野啓、中津祐介
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 性ホルモン結合グルブリン(SHBG)の代謝への影響の検討2015
- Author(s)
  山崎広貴、櫛山暁史、迫田秀之、藤城緑、山本屋武、菊池貴子、金子直、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] DPP4阻害薬anagliptineはLPS投与マウスの肝臓・脂肪組織における炎症反応を抑制する2015
- Author(s)
  新城尊徳、岩下未咲、中津祐介、鎌田英明、迫田秀之、藤城緑、櫛山暁史、浅野知一郎、西村英紀
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] SGLT2阻害薬ルセオグリフロジンによる非アルコール性脂肪性肝炎の改善作用2015
- Author(s)
  藤城緑、中津祐介、迫田秀之、櫛山暁史、松永泰花、山本屋武、鎌田英明、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2015
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山本屋武、山崎広貴、中津祐介、浅野地一郎、河津捷二
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 肝臓におけるLUBAC(linear ubiquitin assembly complex)活性低下はAkt-mTOR経路の亢進および肝での炎症を惹起する2015
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、金子直、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 性ホルモン結合グルブリン(SHBG)の代謝への影響の検討2015
- Author(s)
  山崎広貴、櫛山暁史、迫田秀之、藤城緑、山本屋武、菊池貴子、金子直、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 高脂肪食負荷による近位筋優位遺伝性運動感覚ニューロパチー原因遺伝子TFGの発現低下とその病的意義2015
- Author(s)
  浅野知一郎、松永泰花、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、小野啓、中津祐介
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] DPP4阻害薬anagliptineはLPS投与マウスの肝臓・脂肪組織における炎症反応を抑制する2015
- Author(s)
  新城尊徳、岩下未咲、中津祐介、鎌田英明、迫田秀之、藤城緑、櫛山暁史、浅野知一郎、西村英紀
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討2015
- Author(s)
  松永泰花、中津祐介、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、新城尊徳、岩下未咲、西村英紀、小野啓、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 膵β細胞機能におけるプロリン異性化酵素Pin1の役割2015
- Author(s)
  中津祐介、森馨一、松永泰花、山本屋武、迫田秀之、藤城緑、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 膵β細胞機能におけるプロリン異性化酵素Pin1の役割2015
- Author(s)
  中津祐介、森馨一、松永泰花、山本屋武、迫田秀之、藤城緑、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージとの共培養系においてValsartanが脂肪細胞の遺伝子発現に与える影響2012
- Author(s)
  藤城　緑，郭　榮，張　君，中津　祐介，櫛山　暁史，福嶋　俊明，鎌田　英明，栗原　裕基，内田　隆史，迫田　秀之，浅野　知一郎
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] 長時間高グルコース刺激による肝細胞内インスリン受容体遺伝子発現調節機構の解明2010
- Author(s)
  藤城緑
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市デジタルミュージアム(岡山県)
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22790847
[Presentation] 長時間高グルコース刺激による肝細胞内インスリン受容体蛋白発現調節および活性調節機構の解明2009
- Author(s)
  藤城緑
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20790638
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑、中津祐介、福嶋俊明、松永泰花、迫田秀之、櫛山暁史、山本屋武、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 非アルコール性脂肪肝炎(NASH)に対するクエン酸モサプリド投与の効果
- Author(s)
  藤城緑、中津祐介、大谷裕一郎、大久保博史、岩下未咲、西村英紀、迫田秀之、櫛山暁史、菊池貴子、浅野知一郎
- Organizer
  第 56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] LUBAC (linear ubiquitin chain assembly complex)のインスリンシグナル伝達系における役割の検討
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] Pin1阻害薬Jugloneを用いたNASH治療効果の検討
- Author(s)
  山崎広貴、中津祐介、鎌田英明、西村英紀、菊池貴子、藤城緑、迫田秀之、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] LUBAC (linear ubiquitin chain assembly complex)のインスリンシグナル伝達系における役割の検討
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] DPP4阻害薬anagliptinは、活性化マクロファージおよびマクロファージ共培養下脂肪細胞の炎症反応を抑制する
- Author(s)
  新城尊徳、岩下未咲、中津祐介、迫田秀之、藤城緑、櫛山暁史、鎌田英明、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] LUBAC(linear ubiquitin chain assembly complex)のインスリンシグナル伝達系における役割の検討
- Author(s)
  山本屋武, 迫田秀之, 藤城緑, 山崎広貴, 菊池貴子, 櫛山暁史, 浅野知一郎
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑、中津祐介、福嶋俊明、松永泰花、迫田秀之、櫛山暁史、山本屋武、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 非アルコール性脂肪肝炎発症におけるLUBAC形成障害の役割
- Author(s)
  松永泰花, 中津祐介, 鎌田英明, 福嶋俊明, 岩下未咲, 新城尊徳, 浅野知一郎, 菊池貴子, 藤城緑
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] キサンチンオキシターゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑, 迫田秀之, 山本屋武, 中津祐介, 福嶋俊明, 松永泰花, 浅野知一郎, 櫛山暁史, 西村英紀
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] マクロファージresistin like molecule βによるインスリン抵抗性・動脈硬化発症の機序
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] The Role of Linear Ubiquitin Chain Assembly Complex (LUBAC) and its Components in Insulin Signal Transduction.
- Author(s)
  Yamamotoya T, Sakoda H, Fujishiro M, Kaneko S, Yamazaki H, Kikuchi T, Kushiyama A, Asano T
- Organizer
  74th Scientific Sessions of the American Diabetes Association
- Place of Presentation
  San Francisco
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] 非アルコール性脂肪性肝炎発症におけるLUBAC形成障害の役割
- Author(s)
  松永泰花、中津祐介、鎌田英明、福嶋俊明、岩下未咲、新城尊徳、菊池貴子、藤城緑、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージresistin like molecule βによるインスリン抵抗性・動脈硬化発症の機序
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 糖尿病外来における消化器症状調査結果
- Author(s)
  山崎　広貴，藤城　緑，金子　直，纐纈　優子，山本屋　武，迫田　秀之，植木　浩二郎，門脇　孝
- Organizer
  第 56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] Mosapride citrate improves non-alcoholic steatohepatitis with increased faecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.
- Author(s)
  H. Okubo, M. Yoneda, H. Sakoda, A. Kushiyama, M. Fujishiro, Y. Nakatsu, T. Fukushima1, Y. Matsunaga, H. Kamata, M. Iwashita, F. Nishimura, A. Tomoichiro
- Organizer
  50th EASD Annual Meeting
- Place of Presentation
  Vienna
- Year and Date
  2014-09-15 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-24591314
[Presentation] DPP4阻害薬anagliptinは、活性化マクロファージおよびマクロファージ共培養下脂肪細胞の炎症反応を抑制する
- Author(s)
  新城尊徳、岩下未咲、中津祐介、迫田秀之、藤城緑、櫛山暁史、鎌田英明、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 非アルコール性脂肪性肝炎発症におけるLUBAC形成障害の役割
- Author(s)
  松永泰花、中津祐介、鎌田英明、福嶋俊明、岩下未咲、新城尊徳、菊池貴子、藤城緑、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] Pin1阻害薬Jugloneを用いたNASH治療効果の検討
- Author(s)
  山崎広貴、中津祐介、鎌田英明、西村英紀、菊池貴子、藤城緑、迫田秀之、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451

1. ASANO Tomoichiro (70242063)

# of Collaborated Projects: 6 results

# of Collaborated Products: 66 results
2. SAKODA Hideyuki (50376464)

# of Collaborated Projects: 4 results

# of Collaborated Products: 53 results
3. UCHIJIMA Yasunobu (90272426)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NAKATSU YUSUKE (20452584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 51 results
5. FUKUSHIMA TOSHIAKI (70543552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
6. HONDA HIROAKI (40245064)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. SHOJIMA Nobuhiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KUSHIYAMA Akifumi

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. ISHIHARA Hisamitsu (60361086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 栗原裕基 (20221947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 栗原由紀子 (80345040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 市村徹 (50213012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 渡邉健太郎 (80373017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 山名碧 (40869468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TSUKUDA Katsunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ABE Miho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ONO Hiraku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 西村英紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 鎌田英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
20. 片桐秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 小須田南

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujishiro Midori 藤城 緑

FUJISHIRO Midori 藤城 緑

Research Projects

Research Products

Co-Researchers

Elucidation of roles of XOR on impairment of insulin secretion and action in type 2 diabetes with obesityPrincipal Investigator

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Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysis

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Roles of trk-fused gene product protein

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Roles of Pin1 and PAR 14 on the metabolic regulations

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Elucidation of mechanisms by which exercise improves inflammation induced by type 2 diabetesPrincipal Investigator

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Investigation of the role of insulin signaling molecules on development of hepatocytes into hepatocytes with fatty changesPrincipal Investigator

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Clarification of the role of annexin on glucose transportPrincipal Investigator

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mTOR/Raptor、Rictorを介した代謝調節とインスリン感受性への関与Principal Investigator

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Elucidation of the molecular mechanisms underlying metabolic disorders using protemomics analysis

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プロテオーム解析によるインスリン感受性調節機構の解明と新規治療ターゲットの発見

Principal Investigator

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Research Institution

小胞構成蛋白の網羅的解析による糖輸送担体の制御機構および糖尿病における障害の解明

Principal Investigator

Project Period (FY)

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Research Institution

Elucidation of the molecular mechanisms underlying insulin and exercise-induced effects on metabolism and vascular cells

Principal Investigator

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Research Institution

[Journal Article] A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness,2023

Author(s)

Journal Title

Fujishiro Midori 藤城緑

FUJISHIRO Midori 藤城緑