SEKIYA Motobiro 関谷元博

Researcher Number	50420245
Affiliation *help	2016 – 2018 : 筑波大学, 医学医療系, 講師 2009 – 2010 : The University of Tokyo, 医学部附属病院, 助教 2007 : The University of Tokyo, Hospital, Research fellow 2006 – 2007 : 東京大学, 医学部附属病院, 医員 2006 : 東大, 医学部附属病院
Review Section/Research Field	Principal Investigator Metabolomics / Health science and related fields Except Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Metabolomics
Keywords	Principal Investigator コレステロール / コレステロールエステル / ゲノム / 泡沫化 / 脂質 / 糖尿病 / マクロファージ / 発現制御 / 内科 / 水解 … More Except Principal Investigator … More

脂質の量と質が制御するオルガネラ恒常性の分子機構の解明Ongoing
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
新しい栄養代謝産物センサーに注目したエピジェネティクス制御システムの解明Principal InvestigatorOngoing
- Principal Investigator
  
  関谷元博
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  University of Tsukuba
マクロファージ泡沫化における新規代謝調節因子の探索Principal Investigator
- Principal Investigator
  
  関谷元博
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
脂肪組織における新規中性脂肪分解酵素遺伝子欠損マウスの表現型解析Principal Investigator
- Principal Investigator
  
  関谷元博
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
in vivo promoter analysis of lipogenic genes
- Principal Investigator
  
  YAHAGI Naoya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

All 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lepob/ob mice.2009
- Author(s)
  Sekiya M., et al.
- Journal Title
  
  Biochem Biophys Res Commun 387
  
  Pages : 511-515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890053
[Journal Article] Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.2009
- Author(s)
  Sekiya M., et al.
- Journal Title
  
  Cell Metab 10(3)
  
  Pages : 219-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890053
[Journal Article] Hormone-sensitive lipase is involved in hepatic cholesterol ester hydrolysis2008
- Author(s)
  Sekiya M, Osuga J, Yahagi N, et. al.
- Journal Title
  
  J Lipid Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590979
[Journal Article] Hormone-sensitive lipase is involved in hepatic cholesterol ester hydrolysis.2008
- Author(s)
  Sekiya M, et. al.
- Journal Title
  
  J Lipid Res (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590979
[Journal Article] Sterol regulatory element-binding protein(SREBP)-1-independent regulation of lipogenic gene expression in adipocytes.2007
- Author(s)
  Sekiya M, Yanagi N, et al.
- Journal Title
  
  J Lipid Res (in press)
- Data Source
  KAKENHI-PROJECT-18590979
[Journal Article] Sterol regulatory element-binding protein(SREBP) -1-independent regulation of lipogenic gene expression in adipocytes2007
- Author(s)
  Sekiya M, Yahagi N, et. al.
- Journal Title
  
  J Lipid Res 48
  
  Pages : 1581-91
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590979
[Journal Article] Sterol regulatory element-binding protein (SREBP)-1-independent regulation of lipogenic gene expression in adipocytes.2007
- Author(s)
  Sekiya M, Yahagi N, et. al.
- Journal Title
  
  J Lipid Res 48
  
  Pages : 1581-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590979
[Journal Article] Sterol regulatory element-binding protein(SREBP)-1-independent regulation of lipogenic gene expression in adipocytes.2007
- Author(s)
  Sekiya M, Yahagi N, et. al.
- Journal Title
  
  J Lipid Res 48
  
  Pages : 1581-91
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] 新規に同定されたリパーゼNCEHはマクロファージの主要な中性コレステロールエステラーゼである2009
- Author(s)
  関谷元博
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21890053
[Presentation] A Novel Lipase, Neutral Cholesterol Ester Hydrolase, is a major regulator of Neutral Cholesterol Ester Hydrolysis in Macrophages.2009
- Author(s)
  関谷元博
- Organizer
  第41回日本動脈硬化学会総会・学術集会
- Place of Presentation
  山口
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-21890053
[Presentation] 新規に同定されたマクロファージコレステロールエステラーゼ(MCEH)は泡沫化現象を規定するリパーゼである2007
- Author(s)
  関谷元博、他
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] 新規に同定されたマクロファージコレステロールエステラーゼ(MCEH)は泡沫化現象を規定するリパーゼである2007
- Author(s)
  関谷元博、他
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] 新規に同定されたマクロファージコレステロールエズテラーゼ(MCEH)は泡沫化現象を規定するリパーゼである2007
- Author(s)
  関谷元博, 他
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] 新規に同定されたマクロファージコレステロールエステラゼ(MCEH)は泡沫化現象を規定するリパーゼである2007
- Author(s)
  関谷元博, 他
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] マクロファージにおいて新規に同定されたコレステロールエステラーゼ(MCEH)のin vivo解析2006
- Author(s)
  関谷元博, 他
- Organizer
  第49回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] 新規に同定されたコレステロールエステラーゼ(MCEH)は未同定であったマクロファージの中性コレステロールエステラーゼである2006
- Author(s)
  関谷元博, 他
- Organizer
  日本分子生物学会2006フォーラム
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590979
[Presentation] マクロファージに発現する新規コレステロールエステラーゼ(macrophage cholesteryl ester hydrolase, MCEH)ノックアウトマウスの解析2006
- Author(s)
  関谷元博, 他
- Organizer
  第38回日本動脈硬化学会総会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590979

1. YAHAGI Naoya (60420246)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
2. OSUGA Jun-ichi (10334400)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
3. IIZUKA Yoko (40420244)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 島野仁 (20251241)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 松坂賢 (70400679)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. 中川嘉 (80361351)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 韓松伊 (80729541)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

SEKIYA Motobiro 関谷 元博

Research Projects

Research Products

Co-Researchers

脂質の量と質が制御するオルガネラ恒常性の分子機構の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新しい栄養代謝産物センサーに注目したエピジェネティクス制御システムの解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マクロファージ泡沫化における新規代謝調節因子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脂肪組織における新規中性脂肪分解酵素遺伝子欠損マウスの表現型解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

in vivo promoter analysis of lipogenic genes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lepob/ob mice.2009

Author(s)

Journal Title

Data Source

[Journal Article] Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Hormone-sensitive lipase is involved in hepatic cholesterol ester hydrolysis2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hormone-sensitive lipase is involved in hepatic cholesterol ester hydrolysis.2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sterol regulatory element-binding protein(SREBP)-1-independent regulation of lipogenic gene expression in adipocytes.2007

Author(s)

Journal Title

Data Source

[Journal Article] Sterol regulatory element-binding protein(SREBP) -1-independent regulation of lipogenic gene expression in adipocytes2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sterol regulatory element-binding protein (SREBP)-1-independent regulation of lipogenic gene expression in adipocytes.2007

Author(s)

Journal Title

Data Source

[Journal Article] Sterol regulatory element-binding protein(SREBP)-1-independent regulation of lipogenic gene expression in adipocytes.2007

Author(s)

Journal Title

Description

Data Source

[Presentation] 新規に同定されたリパーゼNCEHはマクロファージの主要な中性コレステロールエステラーゼである2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A Novel Lipase, Neutral Cholesterol Ester Hydrolase, is a major regulator of Neutral Cholesterol Ester Hydrolysis in Macrophages.2009

Author(s)

Organizer

Place of Presentation

SEKIYA Motobiro 関谷元博