KAMEI Hidehiko 亀井英彦

Researcher Number	50421243
Affiliation (based on the past Project Information) *help	2009 – 2014: 愛知学院大学, 歯学部, 講師 2010: 愛知学院大学, 歯学部, 助教 2007 – 2008: 愛知学院大学, 歯学部, 助教 2006: Aichi-Gakuin University, Dept of Periodontology, Sch of Dent, Assistant Professor, 歯学部, 助手
Review Section/Research Field	Principal Investigator Social dentistry Except Principal Investigator Periodontal dentistry
Keywords	Principal Investigator 喫煙関連歯周炎 / IL1受容体 / アリル頻度 / ロジスティック回帰分析 / 遺伝子多型 / IL1R2 / インターロイキン１受容体 / 一塩基多型 / 遺伝子 / CYP2A6 / ニコチン代謝能 / 歯周炎 / 喫煙 … More Except Principal Investigator … More 歯周病 / 実験的歯周炎 / 歯周炎 / 遺伝子多型 / gene expression / microarray / restraint stress / experimental periodontitis / 遺伝子発現 / マイクロアレイ / 拘束ストレス / プラーク細菌 / う蝕細菌 / ゲノム解析 / 16SrRNA解析 / 臨床株 / プラーク細菌叢 / コチニン / ニコチン / CYP2A6 / 受動喫煙 / ニコチン代謝能 / 社会的ニコチン依存度 / 喫煙 / Tepe II IL-1 receptor / 破骨細胞形成 / ELISA法 / LPS / IL-1 receptor antagonist / Type II IL-1 receptor / IL-1Ra KOマウス / IL-1 / 実験的歯周炎モデル / 炎症性骨吸収 / 炎症性サイトカイン / IL-1Ra欠損マウス / インターロイキン-1レセプターアンタゴニスト / インターロイキン-1タイプIIレセプター / インターロイキン-1 / 歯周免疫機能学 / 16SrRNA遺伝子解析 / 歯肉縁下プラーク / 歯肉縁上プラーク / ゲノムDNA抽出 / 歯周病関連細菌 / 口腔細菌叢 / メタゲノム解析 / インターロイキン-1β / インターフェロンーγ / インターロイキンー4 / マウス歯肉上皮細胞 / 可溶性IL-1タイプ2レセプター / インターロイキンー1β / 侵襲性歯周炎 / 可溶性インターロイキンー1タイプ2レセプター / インターロイキンー1 / 歯肉溝浸出液 Less

A study of the relationship between the reduction of nicotine metabolism and smoking-related periodontitis.Principal Investigator
- Principal Investigator
  
  KAMEI Hidehiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Social dentistry
- Research Institution
  Aichi Gakuin University
Genome sequencing of clinical strains isolated from dental plaque for investigation of polymicrobial factors in periodontal pathogenesis
- Principal Investigator
  
  HAYASHI Jun-ichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Aichi Gakuin University
Implications of CYP2A6 genetic variation for smoking behaviors and periodontal disease
- Principal Investigator
  
  INAGAKI KOJI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Aichi Gakuin University,Junior College
Effect of the IL-1 typeIIreceptor to a experimental periodontitis infected with periodontal bacterium
- Principal Investigator
  
  ISHIHARA Yuichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Aichi Gakuin University
Metagenomic Analysis of Oral Microbiota from Normal Subjects and Patients with Periodontal Disease
- Principal Investigator
  
  NOGUCHI Toshihide
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Aichi Gakuin University
A function of soluble Interleukin-1 receptor type 2 for periodontal tissue
- Principal Investigator
  
  ISHIHARA Yuichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Aichi Gakuin University
Effect of restraint stress on the gene expression in periodontal tissue of rat experimental periodontitis
- Principal Investigator
  
  YOSHINARI Nobuo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Aichi-Gakuin University

All 2014 2013 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 慢性疾患としての歯周病へのアプローチ　患者さんの生涯にわたるQOLに貢献するために2014
- Author(s)
  亀井英彦（分担）
- Total Pages
  252
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-25870860
[Journal Article] Interleukin-1 receptor gene variants are associated with aggressive periodontitis in the Japanese2014
- Author(s)
  Kamei H、Ishihara Y, 12 others
- Journal Title
  
  Arch Oral Biol
  
  Volume: Vol. 59、No. 7 Issue: 7 Pages: 756-763
- DOI
  10.1016/j.archoralbio.2014.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593079, KAKENHI-PROJECT-24593137, KAKENHI-PROJECT-25870860
[Journal Article] Inflammatory bone loss in experimental periodontitis induced by Aggregatibacter actinomycetemcomitans in IL-1Ra knockout mice.2014
- Author(s)
  Izawa A, Ishihara Y, Mizutani H, Kobayashi S, Goto H, Okabe E, Takeda H, Ozawa Y, Kamiya Y, Sugita Y, Kubo K, Kamei H, Kikuchi T, Mitani A, Hayashi J, Nishihara T, Maeda H, Noguchi T.
- Journal Title
  
  Infect Immun.
  
  Volume: 82 Pages: 1904-13
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870860
[Journal Article] IL-1 Receptor Type II production is upregulated by IL-4 and IL-13, and downregulated by IFN-gamma in mouse gingival epithelial cells2014
- Author(s)
  Kamiya Y, Ishihara Y, Kamei H, Ozawa Y, Mizutani H, Kubo K, Maeda H and Noguchi T
- Journal Title
  
  Modern Research in Inflammation
  
  Volume: 3 Pages: 37-47
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25870860
[Journal Article] Management of traumatic dental injury after periodontal surgery in patient with hereditary gingival fibromatosis: Case report2014
- Author(s)
  Koji Inagaki, Hidehiko Kamei, Akio Mitani, Toshihide Noguchi
- Journal Title
  
  Oral Health and Dental Management
  
  Volume: 13 Pages: 260-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870860
[Journal Article] IL-1ファミリーとIL-1受容体：歯周病疾患マーカーや治療薬としての可能性2014
- Author(s)
  石原裕一，亀井英彦，神谷洋介，伊澤有郎，水谷大樹，鈴木万里代，野口俊英，三谷章雄
- Journal Title
  
  日本歯周病学会会誌
  
  Volume: 56 Pages: 272-280
- NAID
  130004842577
- Data Source
  KAKENHI-PROJECT-25870860
[Journal Article] Management of traumatic dental injury after periodontal surgery in patient with hereditary gingival fibromatosis: Case report2014
- Author(s)
  Inagaki K, Kamei H, Mitani A, Noguchi T
- Journal Title
  
  Oral Health Dent Manag
  
  Volume: 13(2) Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593079
[Journal Article] Soluble Interleukin-1 Receptor Type II Levels in Gingival Crevicular Fluid in Aggressive and Chronic Periodontitis2008
- Author(s)
  Suzuki M, Ishihara.Y, Kamei H, 10名
- Journal Title
  
  J Periodontol 79巻
  
  Pages: 495-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592397
[Presentation] High levels of sIL-1RAcP was observed in chronic periodontitis patients.2014
- Author(s)
  Yosuke Kamiya, Yuichi Ishihara, Hidehiko Kamei, Ario Izawa, Eijiro Okabe, Hisashi Goto, Akane Kuno, Yuji Sugawa, Yusuke Ozawa and Akio Mitani
- Organizer
  2014 Annual Meeting of American Academy of Periodontology
- Place of Presentation
  San Francisco
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-25870860
[Presentation] 姉弟に発症した遺伝性歯肉線維腫症に対する包括的治療報告2014
- Author(s)
  亀井英彦、稲垣幸司、横井　共、中山敦史、吉田憲司、酒井直子、栗田賢一、後藤滋巳、三谷章雄
- Organizer
  第57回秋期日本歯周病学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-25870860
[Presentation] 顕著な歯列不正を伴う慢性歯周炎・咬合性外傷にチームアプローチで対応した包括的治療症例2014
- Author(s)
  亀井英彦，田中繁寿，河村光輝，平井秀明，田中奈央，田中孝，杉浦進介，川瀬仁史，三輪晃資，尾藤　睦，田中貴信，安藤和枝，岡田通夫，野口俊英，三谷章雄
- Organizer
  第９回日本歯周病学会中部地区大学・日本臨床歯周病学会中部支部合同研究会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25870860
[Presentation] 重症高血圧患者における薬物性歯肉増殖症の治療方針に関する一提案：ニフェジピンを同系Ca拮抗薬へ変更し，歯周基本治療により改善を認めた一症例2014
- Author(s)
  亀井英彦、稲垣幸司、松原達昭、野口俊英
- Organizer
  第57回春期日本歯周病学会学術大会
- Place of Presentation
  岐阜
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25870860
[Presentation] 歯列不正を伴う慢性歯周炎患者に対し包括的歯科治療を行い審美的改善が得られた１症例2014
- Author(s)
  平井秀明，亀井英彦，河村光輝，杉山慎太郎，三谷章雄，田中貴信
- Organizer
  第25回日本歯科審美学会学術大会
- Place of Presentation
  高松
- Year and Date
  2014-11-22
- Data Source
  KAKENHI-PROJECT-25870860
[Presentation] Smoking-related cognition, secondhand smoke exposure, the awareness of smoking and the effects of anti-smoking education for fifth and sixth grade elementary school children2013
- Author(s)
  Inagaki K、Kamei H、13 others
- Organizer
  The 10th Meeting of Asia Pacific Conference on Tobacco or Health 2013
- Place of Presentation
  Makuhari, Japan
- Year and Date
  2013-08-21
- Data Source
  KAKENHI-PROJECT-23593079
[Presentation] プラーク細菌叢のメタゲノム解析2011
- Author(s)
  林潤一郎、亀井英彦、福田光男、石原裕一、野口俊英
- Organizer
  第54回秋季日本歯周病学会
- Place of Presentation
  下関
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21592638
[Presentation] IL-1Ra欠損マウス腹腔マクロファージにおける骨吸収活性の解析2011
- Author(s)
  水谷大樹, 石原裕一, 伊澤有郎, 小澤佑介, 神谷洋介, 亀井英彦, 田中繁寿, 三谷章雄, 久保勝俊, 西原達次, 前田初彦, 野口俊英
- Organizer
  第3回口腔先端応用医科学研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21592638
[Presentation] 小学生の喫煙，受動喫煙に対する意識と社会的ニコチン依存度2011
- Author(s)
  稲垣幸司，生井エリナ，亀井英彦，野口俊英，森田一三，中垣晴男，遠藤　明，大谷哲也，磯村　毅，吉井千春，加濃正人
- Organizer
  第２回日本小児禁煙研究会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23593079
[Presentation] ヒト歯周病細菌叢のメタゲノム解析2011
- Author(s)
  林潤一郎,近藤伸二、亀井英彦、森田英利、足立直樹、福田光男、Todd D Taylor、石原裕一、小島俊男、野口俊英
- Organizer
  第5回日本ゲノム微生物学会
- Place of Presentation
  仙台
- Year and Date
  2011-03-14
- Data Source
  KAKENHI-PROJECT-20249082
[Presentation] ラット実験的歯周炎における破骨細胞形成とIL-1ファミリーの動態2010
- Author(s)
  小澤佑介, 石原裕一, 水谷大樹, 伊澤有郎, 亀井英彦, 田中繁寿, 林潤一郎、三谷章雄, 神谷洋介, 西原達次, 前田初彦, 野口俊英
- Organizer
  第53回秋季日本歯周病学会
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21592638
[Presentation] Metagenomic analysis of the dental plaque2010
- Author(s)
  Hayashi J, Kondo S, Morita H, Kamei H, Fukuda M, Ishihara Y, Kojima T, Noguchi T
- Organizer
  96^<th> American Academy of Periodotology Annual Meeting
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-20249082
[Presentation] IL-1RaKOマウス腹腔マクロファージからのIL-1産生亢進2010
- Author(s)
  水谷大樹, 石原裕一, 伊澤有郎, 小澤佑介, 相野誠、神谷洋介, 亀井英彦, 田中繁寿, 三谷章雄, 西原達次, 前田初彦, 野口俊英
- Organizer
  第53回秋季日本歯周病学会
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21592638
[Presentation] Interleukin-1 receptor type2 production from mouse gingival epithelial cell2009
- Author(s)
  Y. Ishihara, Y. Kamiya, Y. Ozawa, A. Nagahara, H. Mizutani, S. Tanaka, H. Kamei, T. Noguchi
- Organizer
  The 95th annual meeting of the American Academy of Periodontology
- Place of Presentation
  Boston, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21592638
[Presentation] 禁煙支援に必要な無煙タバコ（Smokeless Tobacco）の基礎知識
- Author(s)
  稲垣幸司，埴岡　隆，北田雅子，山岡雅顕，井埜利博，亀井英彦，三谷章雄，野口俊英
- Organizer
  第４回日本小児禁煙研究会
- Place of Presentation
  ウィリング横浜 (横浜市港南区)
- Data Source
  KAKENHI-PROJECT-23593079
[Presentation] 緊急トピックス：禁煙支援に必要な無煙タバコ（Smokeless Tobacco）の基礎知識
- Author(s)
  稲垣幸司、埴岡　隆、北田雅子、山岡雅顕、井埜利博、亀井英彦、野口俊英
- Organizer
  第4回日本小児禁煙研究会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25870860
[Presentation] Smoking-related cognition, secondhand smoke exposure, the awareness of smoking and the effects of anti-smoking education for fifth and sixth grade elementary school children
- Author(s)
  Inagaki K, Kamei H, Noguchi T, Morita I, Ieda S, Isomura T, Uozumi K, Ohsawa I, Taniguchi C, Yamaguchi Y, Kitada M, Endo A, Yoshii C, Kano M.
- Organizer
  The 10th Meeting of Asia Pacific Conference on Tobacco or Health 2013
- Place of Presentation
  幕張メッセ (千葉市美浜区)
- Data Source
  KAKENHI-PROJECT-23593079
[Presentation] Smoking-related cognition, secondhand smoke exposure, the awareness of smoking and the effects of anti-smoking education among fifth and sixth grade elementary school children
- Author(s)
  Inagaki Koji，Hidehiko Kamei，Noguchi Toshihide，Ichizo Morita，Shigeharu Ieda，Takeshi Isomura，Kimiko Uozumi，Isao Ohsawa，Chie Taniguchi，Yukinobu Yamaguchi，Akira Endo，Tetsuya Otani，Chiharu Yopsii，Masato Kano
- Organizer
  The 10th APACT Conference
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-25870860

1. ISHIHARA Yuichi (50261011)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. HAYASHI Junichiro (30350937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. MORITA Hidetoshi (70257294)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. HATTORI Masahira (70175537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MITANI Akio (50329611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 田中繁寿 (30367619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. NOGUCHI Toshihide (50014262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KOJIMA Toshio (00311340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. FUKUDA Mitsuo (40156790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. TOH Hidehiro (10353468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. INAGAKI KOJI (50211058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. MORITA Ichizo (50301635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. MORITA Hidetoshi (70957294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YOSHINARI Nobuo (20231699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 川瀬仁史 (60329612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 祖父江尊範 (90319195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 鈴木万里代

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 神谷洋介

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAMEI Hidehiko 亀井 英彦

Research Projects

Research Products

Co-Researchers

A study of the relationship between the reduction of nicotine metabolism and smoking-related periodontitis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome sequencing of clinical strains isolated from dental plaque for investigation of polymicrobial factors in periodontal pathogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Implications of CYP2A6 genetic variation for smoking behaviors and periodontal disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of the IL-1 typeIIreceptor to a experimental periodontitis infected with periodontal bacterium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metagenomic Analysis of Oral Microbiota from Normal Subjects and Patients with Periodontal Disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A function of soluble Interleukin-1 receptor type 2 for periodontal tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of restraint stress on the gene expression in periodontal tissue of rat experimental periodontitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 慢性疾患としての歯周病へのアプローチ 患者さんの生涯にわたるQOLに貢献するために2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Interleukin-1 receptor gene variants are associated with aggressive periodontitis in the Japanese2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammatory bone loss in experimental periodontitis induced by Aggregatibacter actinomycetemcomitans in IL-1Ra knockout mice.2014

Author(s)

Journal Title

Data Source

[Journal Article] IL-1 Receptor Type II production is upregulated by IL-4 and IL-13, and downregulated by IFN-gamma in mouse gingival epithelial cells2014

Author(s)

Journal Title

Data Source

[Journal Article] Management of traumatic dental injury after periodontal surgery in patient with hereditary gingival fibromatosis: Case report2014

Author(s)

Journal Title

Data Source

[Journal Article] IL-1ファミリーとIL-1受容体：歯周病疾患マーカーや治療薬としての可能性2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Management of traumatic dental injury after periodontal surgery in patient with hereditary gingival fibromatosis: Case report2014

Author(s)

Journal Title

Data Source

[Journal Article] Soluble Interleukin-1 Receptor Type II Levels in Gingival Crevicular Fluid in Aggressive and Chronic Periodontitis2008

Author(s)

Journal Title

KAMEI Hidehiko 亀井英彦

[Book] 慢性疾患としての歯周病へのアプローチ　患者さんの生涯にわたるQOLに貢献するために2014

[Presentation] 重症高血圧患者における薬物性歯肉増殖症の治療方針に関する一提案：ニフェジピンを同系Ca拮抗薬へ変更し，歯周基本治療により改善を認めた一症例2014