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OHTA Miki  大田 幹

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大田 幹  オオタ ミキ

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Researcher Number 50422283
Affiliation (based on the past Project Information) *help 2009: 東京大学, 医学部附属病院, 医員
2007: The University of Tokyo, 医学部・附属病院, 医員
2006 – 2007: 東京大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Gastroenterology
Except Principal Investigator
Gastroenterology
Keywords
Principal Investigator
SMOたんぱく / Hodgehogシグナル / Hedgehogシグナル / Hedgehog interacting protein / 肝細胞癌 / MAPキナーゼ / GLI転写因子 / 胃癌
Except Principal Investigator
APC / βカテニン … More / β-catenin / TP53 / BRAF / KRAS / LST / 大腸腫瘍 Less
  • Research Projects

    (2 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (3 People)
  •  Molecular biological research on the progression from colorectal benign neoplasm or early cancer to advanced cancer

    • Principal Investigator
      YAMAJI Yutaka
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Hedgehog遺伝子の臓器特異的発現メカニズムと癌の発育進展に与える影響の探索Principal Investigator

    • Principal Investigator
      大田 幹
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo

All 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Macroscopic morphologic subtypes of laterally spreading colorectal tumors showing distinct molecular alterations2010

    • Author(s)
      杉本貴史, 大田幹, 池上恒雄, ほか
    • Journal Title

      Int J Cancer (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590715
  • [Journal Article] Decreased expression of the RAS-GTPase activating protein RASALI is associated with colorectal tumor progression2009

    • Author(s)
      大田幹, 瀬戸元子, 伊地知秀明, ほか
    • Journal Title

      Gastroenterology Jan ; 136(1)

      Pages: 206-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590715
  • [Journal Article] Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II2008

    • Author(s)
      大田幹, 杉本貴史, 瀬戸元子, ほか
    • Journal Title

      Hum Pathol. Sep; 39(9)

      Pages: 1301-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590715
  • [Journal Article] Smoothened gene mutations found in digestive cancer have no aberrant Hedgehog signaling activity.2006

    • Author(s)
      Guleng B, Tateishi K, Ohta M, Asaoka Y, Tanaka Y, Tada M, Seto M, Kanai F, Kawabe T, Omata M
    • Journal Title

      Journal of Gastroenterology 41(12)

      Pages: 1238-1239

    • Data Source
      KAKENHI-PROJECT-18790445
  • [Journal Article] Down-regulation of Hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma

    • Author(s)
      Tada M, Ohta M, Yokosuka O, Omata M, et. al.
    • Journal Title

      Clinical Cancer Research (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790445
  • [Presentation] Differences of Genetic Features in Two Types of Laterally Spreading Tumors of the Colorectum2009

    • Author(s)
      杉本貴史, 大田幹, 山田篤生, ほか
    • Organizer
      DDW 2009
    • Place of Presentation
      Chicago
    • Year and Date
      2009-05-31
    • Data Source
      KAKENHI-PROJECT-19590715
  • [Presentation] 大腸発癌過程における側方発育型大腸腫瘍(LST)2008

    • Author(s)
      杉本貴史, 大田幹, 小俣政男
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-10
    • Data Source
      KAKENHI-PROJECT-19590715
  • [Presentation] 側方発育型大腸腫瘍の形態別による分子生物学的特徴の検討2007

    • Author(s)
      杉本貴史, 大田幹, 小俣政男
    • Organizer
      第18回日本消化器癌発生学会総会
    • Place of Presentation
      札幌・厚生年金会館
    • Year and Date
      2007-11-09
    • Data Source
      KAKENHI-PROJECT-19590715
  • [Presentation] Regulation of the Hedgehog signaling Pathway by Epidermal Growth Factor in Gastric Cancer2007

    • Author(s)
      Seto M, Ohta M, Omata M, et. al.
    • Organizer
      DIGESTIVE DISEASE WEEK, 2007
    • Place of Presentation
      Washington, D. C.
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-18790445
  • [Presentation] The Implication of Hedgehog-interacting Protein in Human Hepatocellular Carcinoma2007

    • Author(s)
      Tada M, Ohta M, Yokosuka O, Omata M, et. al.
    • Organizer
      DIGESTIVE DISEASE WEEK, 2007
    • Place of Presentation
      Washington, D. C.
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-18790445
  • 1.  YAMAJI Yutaka (40376455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  KANAI Fumihiko (70334399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  SUGIMOTO Takafumi (40534920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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