KITANO Hisataka 北野尚孝

Researcher Number	50424726
Other IDs
Affiliation (Current)	2021: 日本大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 日本大学, 医学部, 准教授 2014 – 2016: 日本大学, 医学部, 助教 2011 – 2013: 日本大学, 医学部, 専修指導医 2008 – 2010: Nihon University, 医学部, 専修医
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 癌 / 遺伝子治療 / ゲノム / 遺伝子 / 蛋白質 / バイオテクノロジー

Del1による遺伝子治療と抗体薬の併用療法の効果Principal InvestigatorOngoing
- Principal Investigator
  
  北野尚孝
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Clarification of mechanism of gene therapy with a Del1Principal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The completion of protocol for gene therapy by Del1Principal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The effect of Del-1 by in vivo gene therapyPrincipal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The effected of cancer gene therapy for Del 1 and Fas LPrincipal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University

All 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] Targets in Gene Therapy (ISBN978-953-307-540-2)2011
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Chiaki Hidai
- Total Pages
  12
- Publisher
  InTech Inc
- Data Source
  KAKENHI-PROJECT-22792019
[Journal Article] Nonviral Gene Therapy for Cancer: A Review2018
- Author(s)
  Chiaki Hidai, Hisataka Kitano
- Journal Title
  
  Diseases
  
  Volume: 6 Pages: 1-12
- DOI
  10.3390/diseases6030057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09800
[Journal Article] Efficient cancer gene therapy with a Del1 fragment administered by hypodermic injection in a mouse explanted tumor model2018
- Author(s)
  Hisataka Kitano, Tomomi Ishikawa, Eri Tamura, Shinichiro Kokubun, Chiaki Hidai
- Journal Title
  
  Translational Cancer Researc
  
  Volume: 7 Pages: 686-694
- DOI
  10.21037/tcr.2018.05.45
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09800
[Journal Article] EGF domain of coagulation factor IX is conducive to exposure of phosphatidylserine.2017
- Author(s)
  Chiaki Hidai, Yusuke Fujiwara, Shinichiro Kokubun, Hisataka Kitano.
- Journal Title
  
  Cell Biol Int.
  
  Volume: 41(4) Pages: 374-383
- DOI
  10.1002/cbin.10733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11273
[Journal Article] Long-term gene therapy with Del1 fragment using nonviral vectors in mice with explanted tumors.2016
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Tomomi Ishikawa, Kayo Egoshi, Shinichiro Kokubun, Chiaki Hidai.
- Journal Title
  
  Onco Targets and Therapy.
  
  Volume: 9 Pages: 503-516
- DOI
  10.2147/ott.s90801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11273
[Journal Article] Overexpression of integrin αv facilitates proliferation and invasion of oral squamous cell carcinoma cells via MEK/ERK signaling pathway that is activated by interaction of integrin αvβ8 with type Ⅰ collagen.2014
- Author(s)
  Hayashido Y, Kitano H, Sakaue T, Fujii T, Suematsu M, Sakurai S, Okamoto T
- Journal Title
  
  Int J Oncol.
  
  Volume: 45(5) Pages: 1875-1882
- DOI
  10.3892/ijo.2014.2642
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390455, KAKENHI-PROJECT-24390456, KAKENHI-PROJECT-24593012, KAKENHI-PROJECT-26670865, KAKENHI-PROJECT-26893166
[Journal Article] A Del1 fragment improves the efficiency of FasL genetherapy with a non-viral vector in a mouse explantedtumor model2012
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Shinichiro Kokubun, Chiaki Hidai
- Journal Title
  
  Journal of Gene Medicine
  
  Volume: 14 Pages: 642-650
- DOI
  10.1002/jgm.2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593012
[Journal Article] The Extracellular Matrix Protein Dell Induces Apoptosis viaits Epidermal Growth Factor Motif.2010
- Author(s)
  Hisataka Kitano, Shinichiro Kokubun, Chiaki Hidai.
- Journal Title
  
  Biochemical and Biophysical Research Communications 393(4)
  
  Pages: 757-761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Journal Article] The Extracellular Matr ix Protein Del1 Induces Apoptosis via its Epidermal Growth Factor Motif2010
- Author(s)
  Hisataka Kitano, Shinichiro Kokubun, Chiaki Hidai
- Journal Title
  
  Biochemical and Biophysical Research C ommunications (BBRC). 393(4)
  
  Pages: 757-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Journal Article] The Extraceuar Matrix Protein Del1 Induces Apoptosis via its Epidermal Growth Factor Motif.2010
- Author(s)
  Hisataka Kitano, Shinichiro Kokubun, Chiaki Hidai.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 393(4) Pages: 757-761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792019
[Journal Article] The Del1 deposition domain can immobilize 3α-hydroxysteroid dehydrogenase in the extracellular matrix without interfering with enzymatic activity2009
- Author(s)
  Chiaki Hidai, Hisataka Kitano, Shinichiro Kokubun
- Journal Title
  
  Bioprocess Biosyst Eng. 32(5)
  
  Pages: 569-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Journal Article] The Dell deposition domain can immobilize 3 a -hydroxysteroi d dehydrogenase in the extracellular matrix without interferi ng with enzymatic activity2008
- Author(s)
  Chiaki Hidai, Hisataka Kitano, Shinichiro Kokubun
- Journal Title
  
  Bioprocess Biosyst Eng (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Presentation] An activation peptide of coagulation factor IX increases resistance to hypoxia in hypoxic model mice2017
- Author(s)
  Atsushi Mamiya, Hisataka Kitano, Chiaki Hidai
- Organizer
  12th International conference on cerebral vascular biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] A peptide from coagulation factor IX regulates endothelial barrier function and improves prognosis in traumatic brain injury model2017
- Author(s)
  Yuusuke Fuziwara, Hisataka Kitano,Chiaki Hidai
- Organizer
  12th International conference on cerebral vascular biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] An EGF motif of del1 suppresses notch function and inhibits efficient angiogenesis in vivo.2016
- Author(s)
  Hisataka Kitano
- Organizer
  5th International conference and Exhibition on Pathology
- Place of Presentation
  Chicago
- Year and Date
  2016-05-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] An EGF motif of Del1 suppresses Notch function and inhibits efficient angiogenesis in vivo2015
- Author(s)
  Hisataka Kitano
- Organizer
  American Society of Cell Biology
- Place of Presentation
  San Diego (USA)
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] Enrichment of transgene products with a deposition domain from Del1 protein2012
- Author(s)
  Hisataka Kitano
- Organizer
  SGCT 20th Anniversary Congress jointly organaised with the FSTCG
- Place of Presentation
  Versailles
- Data Source
  KAKENHI-PROJECT-24593012
[Presentation] Del1由来のペプチドによるがん遺伝子治療への応用2012
- Author(s)
  北野　尚孝
- Organizer
  日本口腔外科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593012
[Presentation] A peptide from Dell protein induced apoptosis in vitro2011
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Shinichiro Kokubun, Chiaki Hidai
- Organizer
  The American Society for Cell Biology
- Place of Presentation
  Denver
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-22792019
[Presentation] Coagulation factor IX regulates cell migration via cell membrane
- Author(s)
  北野　尚孝
- Organizer
  日本口細胞生物学会
- Place of Presentation
  奈良県新公会堂（奈良県・奈良市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24593012
[Presentation] Clustering of lipid rafts is accelerated by active coagulation factor IX via exposure to phosphatidylserine at the adhesion complex
- Author(s)
  Hisataka Kitano
- Organizer
  The American Society for Cell Biology
- Place of Presentation
  Philadelphia (USA)
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-24593012

1. 林堂安貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 岡本哲治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 坂上泰士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITANO Hisataka 北野 尚孝

Research Projects

Research Products

Co-Researchers

Del1による遺伝子治療と抗体薬の併用療法の効果Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of mechanism of gene therapy with a Del1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The completion of protocol for gene therapy by Del1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of Del-1 by in vivo gene therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effected of cancer gene therapy for Del 1 and Fas LPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Targets in Gene Therapy (ISBN978-953-307-540-2)2011

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Nonviral Gene Therapy for Cancer: A Review2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient cancer gene therapy with a Del1 fragment administered by hypodermic injection in a mouse explanted tumor model2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EGF domain of coagulation factor IX is conducive to exposure of phosphatidylserine.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term gene therapy with Del1 fragment using nonviral vectors in mice with explanted tumors.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpression of integrin αv facilitates proliferation and invasion of oral squamous cell carcinoma cells via MEK/ERK signaling pathway that is activated by interaction of integrin αvβ8 with type Ⅰ collagen.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Del1 fragment improves the efficiency of FasL genetherapy with a non-viral vector in a mouse explantedtumor model2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Extracellular Matrix Protein Dell Induces Apoptosis viaits Epidermal Growth Factor Motif.2010

Author(s)

Journal Title

Data Source

[Journal Article] The Extracellular Matr ix Protein Del1 Induces Apoptosis via its Epidermal Growth Factor Motif2010

Author(s)

Journal Title

Data Source

[Journal Article] The Extraceuar Matrix Protein Del1 Induces Apoptosis via its Epidermal Growth Factor Motif.2010

Author(s)

Journal Title

KITANO Hisataka 北野尚孝