KITANO Hisataka 北野尚孝

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北野尚孝キタノヒサタカ

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Researcher Number	50424726
Other IDs
Affiliation (Current)	2022: 日本大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022: 日本大学, 医学部, 准教授 2017 – 2020: 日本大学, 医学部, 准教授 2014 – 2016: 日本大学, 医学部, 助教 2011 – 2013: 日本大学, 医学部, 専修指導医 2008 – 2010: Nihon University, 医学部, 専修医
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 癌 / 遺伝子治療 / ゲノム / 遺伝子 / 蛋白質 / バイオテクノロジー / Del1タンパク / 抗がん剤 / CXDXXXXYXCXC

Del1由来のE3C1ペプチドによるによるがん治療の確立Principal Investigator
- Principal Investigator
  
  北野尚孝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Effect of combination therapy of gene therapy with a Del1 and antibody-drugPrincipal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Clarification of mechanism of gene therapy with a Del1Principal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The completion of protocol for gene therapy by Del1Principal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The effect of Del-1 by in vivo gene therapyPrincipal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The effected of cancer gene therapy for Del 1 and Fas LPrincipal Investigator
- Principal Investigator
  
  KITANO Hisataka
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University

All 2021 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] Targets in Gene Therapy (ISBN978-953-307-540-2)2011
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Chiaki Hidai
- Total Pages
  12
- Publisher
  InTech Inc
- Data Source
  KAKENHI-PROJECT-22792019
[Journal Article] Combination Cancer Therapy of a Del1 Fragment and Cisplatin Enhanced Therapeutic Efficiency In Vivo2021
- Author(s)
  Hisataka Kitano, Yoh Masaoka, Atsushi Mamiya, Yusuke Fujiwara, Toshio Miki, Chiaki Hidai.
- Journal Title
  
  In Vivo
  
  Volume: 35 Pages: 779-791
- DOI
  10.21873/invivo.12318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10850, KAKENHI-PROJECT-18K09800
[Journal Article] Nonviral Gene Therapy for Cancer: A Review2018
- Author(s)
  Chiaki Hidai, Hisataka Kitano
- Journal Title
  
  Diseases
  
  Volume: 6 Pages: 1-12
- DOI
  10.3390/diseases6030057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09800
[Journal Article] Efficient cancer gene therapy with a Del1 fragment administered by hypodermic injection in a mouse explanted tumor model2018
- Author(s)
  Hisataka Kitano, Tomomi Ishikawa, Eri Tamura, Shinichiro Kokubun, Chiaki Hidai
- Journal Title
  
  Translational Cancer Researc
  
  Volume: 7 Pages: 686-694
- DOI
  10.21037/tcr.2018.05.45
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09800
[Journal Article] EGF domain of coagulation factor IX is conducive to exposure of phosphatidylserine.2017
- Author(s)
  Chiaki Hidai, Yusuke Fujiwara, Shinichiro Kokubun, Hisataka Kitano.
- Journal Title
  
  Cell Biol Int.
  
  Volume: 41(4) Pages: 374-383
- DOI
  10.1002/cbin.10733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11273
[Journal Article] Long-term gene therapy with Del1 fragment using nonviral vectors in mice with explanted tumors.2016
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Tomomi Ishikawa, Kayo Egoshi, Shinichiro Kokubun, Chiaki Hidai.
- Journal Title
  
  Onco Targets and Therapy.
  
  Volume: 9 Pages: 503-516
- DOI
  10.2147/ott.s90801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11273
[Journal Article] Overexpression of integrin αv facilitates proliferation and invasion of oral squamous cell carcinoma cells via mek/erk signaling pathway that is activated by interaction of integrin αvβ8 with type Ⅰ collagen.2014
- Author(s)
  Hayashido Y, Kitano H, Sakaue T, Fujii T, Suematsu M, Sakurai S, Okamoto T
- Journal Title
  
  Int J Oncol.
  
  Volume: 45(5) Pages: 1875-1882
- DOI
  10.3892/ijo.2014.2642
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390455, KAKENHI-PROJECT-24390456, KAKENHI-PROJECT-24593012, KAKENHI-PROJECT-26670865, KAKENHI-PROJECT-26893166
[Journal Article] A Del1 fragment improves the efficiency of FasL genetherapy with a non-viral vector in a mouse explantedtumor model2012
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Shinichiro Kokubun, Chiaki Hidai
- Journal Title
  
  Journal of Gene Medicine
  
  Volume: 14 Pages: 642-650
- DOI
  10.1002/jgm.2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593012
[Journal Article] The Extracellular Matrix Protein Dell Induces Apoptosis viaits Epidermal Growth Factor Motif.2010
- Author(s)
  Hisataka Kitano, Shinichiro Kokubun, Chiaki Hidai.
- Journal Title
  
  Biochemical and Biophysical Research Communications 393(4)
  
  Pages: 757-761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Journal Article] The Extracellular Matr ix Protein Del1 Induces Apoptosis via its Epidermal Growth Factor Motif2010
- Author(s)
  Hisataka Kitano, Shinichiro Kokubun, Chiaki Hidai
- Journal Title
  
  Biochemical and Biophysical Research C ommunications (BBRC). 393(4)
  
  Pages: 757-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Journal Article] The Extraceuar Matrix Protein Del1 Induces Apoptosis via its Epidermal Growth Factor Motif.2010
- Author(s)
  Hisataka Kitano, Shinichiro Kokubun, Chiaki Hidai.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 393(4) Pages: 757-761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792019
[Journal Article] The Del1 deposition domain can immobilize 3α-hydroxysteroid dehydrogenase in the extracellular matrix without interfering with enzymatic activity2009
- Author(s)
  Chiaki Hidai, Hisataka Kitano, Shinichiro Kokubun
- Journal Title
  
  Bioprocess Biosyst Eng. 32(5)
  
  Pages: 569-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Journal Article] The Dell deposition domain can immobilize 3 a -hydroxysteroi d dehydrogenase in the extracellular matrix without interferi ng with enzymatic activity2008
- Author(s)
  Chiaki Hidai, Hisataka Kitano, Shinichiro Kokubun
- Journal Title
  
  Bioprocess Biosyst Eng (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791551
[Presentation] An activation peptide of coagulation factor IX increases resistance to hypoxia in hypoxic model mice2017
- Author(s)
  Atsushi Mamiya, Hisataka Kitano, Chiaki Hidai
- Organizer
  12th International conference on cerebral vascular biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] A peptide from coagulation factor IX regulates endothelial barrier function and improves prognosis in traumatic brain injury model2017
- Author(s)
  Yuusuke Fuziwara, Hisataka Kitano,Chiaki Hidai
- Organizer
  12th International conference on cerebral vascular biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] An EGF motif of del1 suppresses notch function and inhibits efficient angiogenesis in vivo.2016
- Author(s)
  Hisataka Kitano
- Organizer
  5th International conference and Exhibition on Pathology
- Place of Presentation
  Chicago
- Year and Date
  2016-05-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] An EGF motif of Del1 suppresses Notch function and inhibits efficient angiogenesis in vivo2015
- Author(s)
  Hisataka Kitano
- Organizer
  American Society of Cell Biology
- Place of Presentation
  San Diego (USA)
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-15K11273
[Presentation] Enrichment of transgene products with a deposition domain from Del1 protein2012
- Author(s)
  Hisataka Kitano
- Organizer
  SGCT 20th Anniversary Congress jointly organaised with the FSTCG
- Place of Presentation
  Versailles
- Data Source
  KAKENHI-PROJECT-24593012
[Presentation] Del1由来のペプチドによるがん遺伝子治療への応用2012
- Author(s)
  北野　尚孝
- Organizer
  日本口腔外科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24593012
[Presentation] A peptide from Dell protein induced apoptosis in vitro2011
- Author(s)
  Hisataka Kitano, Atsushi Mamiya, Shinichiro Kokubun, Chiaki Hidai
- Organizer
  The American Society for Cell Biology
- Place of Presentation
  Denver
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-22792019
[Presentation] Coagulation factor IX regulates cell migration via cell membrane
- Author(s)
  北野　尚孝
- Organizer
  日本口細胞生物学会
- Place of Presentation
  奈良県新公会堂（奈良県・奈良市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24593012
[Presentation] Clustering of lipid rafts is accelerated by active coagulation factor IX via exposure to phosphatidylserine at the adhesion complex
- Author(s)
  Hisataka Kitano
- Organizer
  The American Society for Cell Biology
- Place of Presentation
  Philadelphia (USA)
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-24593012

1. 日台智明

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2. 林堂安貴

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3. 岡本哲治

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4. 坂上泰士

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