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NAKASHIMA DAI
中嶋 大
Connect your ORCID iD
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Researcher Number
50431747
Other IDs
Affiliation (Current)
2022: 千葉大学, 大学院医学研究院, 助教
Affiliation (based on the past Project Information)
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2016 – 2022: 千葉大学, 大学院医学研究院, 助教
2017: 千葉大学, 医学部附属病院, 助教
2014 – 2015: 千葉大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related
/
Surgical dentistry
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related
/
Surgical dentistry
Keywords
Principal Investigator
口腔扁平上皮癌 / コラーゲンクロスリンク / Decorin / 口腔扁上皮癌 / S-1 / AKT経路 / AKT 経路 / 術前補助的化学療法 / ノックアウトマウス / CRISPR/Cas9
…
More
/ PLOD2 / LH2 / 胎生致死 / HIF-1α / HIF1-α / 低酸素応答 / 転移モデル / GFP標識癌細胞 / Plod2 / 口腔癌 / クロスリンク解析 / ナノインデンテーション試験 / KOマウス / LH2-derived collagen線維 / 免疫チェックポイント阻害薬 / Lysyl Hydroxylase 2
…
More
Except Principal Investigator
口腔癌 / セツキシマブ / 遺伝子パスウェイ解析 / エクソソーム / miRNA / non coding RNA / 環状RNA / 口腔扁平上皮癌 / スーパーエンハンサー / H3K27ac / 頭頚部癌 / 耐性 / PLAUR / Resveratrol / 頭頸部癌 / PLAUR阻害薬 / cetuximab / MTS assay / in vivo / セツキシマブ耐性 / sh導入 / drug delivery system / siRNA / ミサイル療法 / ファージディスプレイ / ファージディスプレイ法 / 樹状細胞 / PAF / PAFR / オート・クライン / CDDP / Ginkgolide B / 癌 / non codingRNA / circRNA / circRNA Array / circRNA miRNA / CircRNA Array / ChIP-seq 法 / 組織特異性 / 疾患特異性 / 機能特異性 / エピジェネティックな修飾 / スーパーエンハンサー(SE) / Chip-seq法 / H3K27 / long non coding RNA / CHIP-seq / 薬剤耐性 / PRAUR / ChiPseq法 / BRD4 / スーパーエンハンサー薬剤耐性 / microRNA
Less
Research Projects
(
10
results)
Research Products
(
1
results)
Co-Researchers
(
12
People)
Project Start Year (Newest)
Project Start Year (Oldest)
癌抑制型人工合成環状RNAによる癌進展抑制メカニズムの解明と創薬の開発
Principal Investigator
笠松 厚志
Project Period (FY)
2022 – 2024
Research Category
Grant-in-Aid for Scientific Research (B)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
LH2-Colをターゲットとする免疫チェックポイント耐性克服療法の開発
Principal Investigator
Principal Investigator
中嶋 大
Project Period (FY)
2022 – 2024
Research Category
Grant-in-Aid for Scientific Research (C)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
スーパーエンハンサーを標的とした口腔癌薬剤耐性機構の解明による治療法開発
Principal Investigator
鵜澤 一弘
Project Period (FY)
2020 – 2022
Research Category
Grant-in-Aid for Scientific Research (B)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
Elucidation of the mechanism of platelet-activating factor (PAF)-associated cell proliferation in cancer and non-cancer cells.
Principal Investigator
Iyoda Manabu
Project Period (FY)
2019 – 2021
Research Category
Grant-in-Aid for Scientific Research (C)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
Elucidation of the role of non-coding RNA adsorbed cyclic RNA in cancer growth invasion and metastasis.
Principal Investigator
Kasamatsu Atsushi
Project Period (FY)
2019 – 2021
Research Category
Grant-in-Aid for Scientific Research (B)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
口腔癌悪性度を決定するスーパーエンハンサーによる系統的転写制御機構の解明
Principal Investigator
椎葉 正史
Project Period (FY)
2019 – 2021
Research Category
Grant-in-Aid for Scientific Research (B)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
Evaluate changes in collagen cross-linking in lysyl hydroxylase 2 knockout mice and elucidate the role of PLOD2 in cancer metastasis
Principal Investigator
Principal Investigator
Nakashima Dai
Project Period (FY)
2018 – 2020
Research Category
Grant-in-Aid for Scientific Research (C)
Review Section
Basic Section 57060:Surgical dentistry-related
Research Institution
Chiba University
Development of siRNA / missile therapy using exosomes for oral cancer cells
Principal Investigator
Uzawa Katsuhiro
Project Period (FY)
2017 – 2019
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Chiba University
Elucidation of the resistant mechanism and the development of drugs for overcoming resistance against Cetuximab in head and neck cancer.
Principal Investigator
OGAWARA Katsunori
Project Period (FY)
2015 – 2017
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Chiba University
Development of the new predictive method of S-1 neoadjuvant chemosensitivity using Decorin
Principal Investigator
Principal Investigator
NAKASHIMA DAI
Project Period (FY)
2014 – 2015
Research Category
Grant-in-Aid for Research Activity Start-up
Research Field
Surgical dentistry
Research Institution
Chiba University
All
2020
All
Presentation
[Presentation] 安藤壽晃癌抑制型環状RNA: 口腔癌誘発性マイクロRNAの特異的吸着効果による新規診断法の開発
2020
Author(s)
安藤壽晃 鵜澤一弘 笠松厚志 田中希 野淵嵩史 駒綾香 大島早智 伊豫田学 中嶋大 坂本洋右 椎葉正史
Organizer
日本口腔外科学会
Data Source
KAKENHI-PROJECT-19H03847
# of Projects (Dsc)
# of Projects (Asc)
1.
Uzawa Katsuhiro
(30302558)
# of Collaborated Projects:
6 results
# of Collaborated Products:
1 results
2.
Kasamatsu Atsushi
(60375730)
# of Collaborated Projects:
5 results
# of Collaborated Products:
1 results
3.
丹沢 秀樹
(50236775)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
Iyoda Manabu
(40431746)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
椎葉 正史
(20301096)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
坂本 洋右
(50451745)
# of Collaborated Projects:
2 results
# of Collaborated Products:
1 results
7.
OGAWARA Katsunori
(20372360)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
大和地 正信
(70451747)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
小池 一幸
(10618060)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
関 直彦
(50345013)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
田村 裕
(50263174)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
菅波 晃子
(10527922)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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