Tanaka Aki 田中亜紀

… Alternative Names

Researcher Number	50432109
Affiliation (Current)	2021: 富山大学, 学術研究部薬学・和漢系, 助教
Affiliation (based on the past Project Information) *help	2019: 富山大学, 学術研究部薬学・和漢系, 助教 2015 – 2018: 富山大学, 大学院医学薬学研究部(薬学), 助教 2009 – 2010: University of Toyama, 医学薬学研究部(薬学), 助教 2009: 富山大学, 大学院・医学薬学研究部, 助教 2006: 富山大学, 大学院医学薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 基本転写因子 / 転写 / TFIIE / 遺伝子発現制御 / 生化学 / TFIIH / 癌抑制遺伝子産物p53 / 免疫沈降実験 / 癌抑制遺伝子産物 p53 / 遺伝子発現 … More Except Principal Investigator RNAポリメラーゼII(Pol II) / 基本転写因子TFIIH / CTD / メディエーター複合体 / リン酸化 / コファクター / TFIIE / フォークヘッドドメイン / ルディエーター複合体 / CDK19 / 酵母2ハイブリッド法 / Rpb5 / 基本転写因子 / TFIIEβ / Rpb / MED15 / KIXドメイン / CDK8 / CDK11 / TFIIH / Rpb12 / Znフィンガードメイン Less

基本転写因子によるRNAポリメラーゼIIの構造変換の分子機構の解析Principal InvestigatorOngoing
- Principal Investigator
  
  田中亜紀
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Toyama
Transcriptional regulatory mechanism of the RNA polymerase II initiation complex by the chromatin remodeling complexPrincipal Investigator
- Principal Investigator
  
  Tanaka Aki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Toyama
Molecular mechanism of apoptotic pathway through the tumor suppressor protein p53 approached from gene expression controlPrincipal Investigator
- Principal Investigator
  
  TANAKA Aki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Toyama
Unified crosstalk of signal transduction, chromatin regulation, and RNA processing by transcription complexes
- Principal Investigator
  
  OHKUMA Yoshiaki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama

All 2019 2018 2017 2016 2015 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-kappaB and C/EBPbeta on stimulation of Toll-like receptor 9.2017
- Author(s)
  Yamamoto, S., Hagihara, T., Horiuchi, Y., Okui, A., Wani, S., Yoshida, T., Inoue, T., Tanaka, A., Ito, T., Hirose, Y., and Ohkuma, Y.
- Journal Title
  
  Genes Cells
  
  Volume: 22 Pages: 265-276
- DOI
  10.1111/gtc.12475
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24118003, KAKENHI-PROJECT-15K01352, KAKENHI-PROJECT-15K18861, KAKENHI-PROJECT-17K07282, KAKENHI-PROJECT-17H04044
[Journal Article] Association of the winged helix motif of the TFIIEα subunit of TFIIE with either the TFIIEβ subunit or TFIIB distinguishes its functions in transcription.2015
- Author(s)
  Tanaka, A., Akimoto, Y., Kobayashi, S., Hisatake, K., Hanaoka, F., and Ohkuma, Y.
- Journal Title
  
  Genes to Cells
  
  Volume: 20 Pages: 203-216
- DOI
  10.1111/gtc.12212
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24118003, KAKENHI-PROJECT-15K18861, KAKENHI-PUBLICLY-25131704, KAKENHI-PROJECT-25460354
[Journal Article] Human Mediator MED17 Subunit Plays Essential Roles in Gene Regulation by Associating with both Transcription and DNA Repair Machineries.2015
- Author(s)
  Kikuchi, Y., Umemura, H., Nishitani, S., Iida, S., Fukasawa, R., Hayashi, H., Hirose, Y., Tanaka, A., Sugasawa, K. and Ohkuma, Y.
- Journal Title
  
  Genes Cells
  
  Volume: 20 Pages: 191-202
- DOI
  10.1111/gtc.12210
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23116008, KAKENHI-PLANNED-24118003, KAKENHI-PROJECT-15K18861, KAKENHI-PUBLICLY-25131704
[Journal Article] The central forkhead domain of the small subunit of TFIIE plays a primary role in double-stranded DNA binding at transcription initiation2009
- Author(s)
  Tanaka, A.
- Journal Title
  
  Genes Cells 14
  
  Pages: 395-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Central forkhead domain of human TFIIE beta plays a primary role in binding double-stranded DNA at transcription initiation.2009
- Author(s)
  Tanaka A, Watanabe T, Iida Y, Hanaoka F, Ohkuma Y.
- Journal Title
  
  Genes Cells. Vol.14
  
  Pages: 395-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790066
[Journal Article] The central forkhead domain of the small subunit of TFIIE plays a primaryrole in double-stranded DNA binding at transcription initiation.2009
- Author(s)
  Tanaka, A., Watanabe, T., Iida, Y., Hanaoka, F., Ohkuma, Y.
- Journal Title
  
  Genes Cells 14
  
  Pages: 395-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] The central forkhead domain of the small subunit of TFIIE plays a primary role in double-stranded DNA binding at transcription initiation2009
- Author(s)
  Tanaka, A., Watanabe, T., Iida, Y., Hanaoka, F., Ohkuma, Y
- Journal Title
  
  Genes Cells 14
  
  Pages: 395-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Human Mediator Kinase Subunit CDK11 Plays a Negative Role in Viral Activator VP16-dependent Transcription2008
- Author(s)
  Tsutsui, T., Umemura, H., Tanaka, A., Mizuki, F., Hirose, Y., Ohkuma, Y
- Journal Title
  
  Genes Cells 13
  
  Pages: 817-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Structural insight into the TFIIE/TFIIH: TFIIE and p53 share the binding region on TFIIH2008
- Author(s)
  Okuda, M., *Tanaka, A., Satoh, M., Takazawa, M., Mizuta, S., Ohkuma, Y., Nishimura, Y
- Journal Title
  
  EMBO J 27
  
  Pages: 1161-1171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] A kinase subunit of the human Mediator complex, CDK8, positively regulates transcriptional activation2007
- Author(s)
  Furumoto, T., Tanaka, A., Ito, M., Malik, S., Hirose, Y., Hanaoka, F., Ohkuma, Y
- Journal Title
  
  Genes Cells 12
  
  Pages: 119-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation2005
- Author(s)
  Hayashi, K., Watanabe, T., Tanaka, A., Furumoto, T., Sato-Tsuchiya, C., Kimura, M., Yokoi, M., Ishihama, A., Hanaoka, F., Ohkuma, Y
- Journal Title
  
  Genes Cells 10
  
  Pages: 207-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Journal Article] Structural insights into the asymmetric effects of zinc-ligand cysteine mutations in the novel zinc ribbon domain of human TFIIEα for transcription2005
- Author(s)
  Okuda, M., Tanaka, A., Hanaoka, F., Ohkuma, Y., Nishimura, Y
- Journal Title
  
  J. Biochem 138
  
  Pages: 443-449
- NAID
  10017347670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] メディエーター複合体キナーゼCDK8/19はNuRDクロマチンリモデリング複合体サブユニットCHD3/4に結合する2019
- Author(s)
  前田将大1, 藤田智陽, 安倍光姫, 山崎愛実, 深澤力也, 田中亜紀, 廣瀬豊, 大熊芳明
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06654
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体 Kinaseモジュールの機能解析2019
- Author(s)
  海戸優作、原子空、丹澤円香、林裕人、藤田智陽、飯田智、田中亜紀、廣瀬豊、大熊芳明
- Organizer
  日本薬学会北陸支部第131回例会
- Data Source
  KAKENHI-PROJECT-18K06654
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体Kinaseモジュールの機能解析2019
- Author(s)
  原子空, 丹澤円, 林裕人, 藤田智陽, 飯田智, 田中亜紀, 廣瀬豊, 大熊芳明
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06654
[Presentation] 基本転写因子TFIIE とクロマチン構造変換複合体による転写制御機構2018
- Author(s)
  田中亜紀, 山田佑里香, 小林聡子, 廣瀬豊, 大熊芳明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子による転写開始から伸長への移行の制御機構解析2018
- Author(s)
  平山翼, 福岡瑞希, 田中亜紀, 廣瀬豊, 大熊芳明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 転写伸長因子DSIFのPol IIへのリクルートにおけるSpt5の酸性領域とp62の関与の検討2018
- Author(s)
  平山翼、田中亜紀、廣瀬豊、大熊芳明
- Organizer
  生化学会北陸支部第36回大会
- Data Source
  KAKENHI-PROJECT-18K06654
[Presentation] 試験管内再構成系を用いたヒトメディエーター複合体 Kinase モジュールの機能解析2018
- Author(s)
  原子空、丹澤円、林裕人、藤田智陽、飯田智、田中亜紀、廣瀬豊、大熊芳明
- Organizer
  生化学会北陸支部第36回大会
- Data Source
  KAKENHI-PROJECT-18K06654
[Presentation] 転写伸長因子DSIFのPol IIへのリクルートにおけるSpt5酸性領域とTFIIH p62の関与の検討2018
- Author(s)
  依田ちづる、平山翼、田中亜紀、廣瀬豊、大熊芳明
- Organizer
  日本薬学会北陸支部第130回例会
- Data Source
  KAKENHI-PROJECT-18K06654
[Presentation] 基本転写因子TFIIEの転写開始から伸長への移行段階における役割の解析2017
- Author(s)
  田中亜紀、福岡瑞希、平山翼、廣瀬豊、大熊芳明
- Organizer
  ConBio2017(第40回日本分子生物学会年会、第90回日本生化学会大会)
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 真核生物RNAポリメラーゼIIは転写初期段階に外側と内側からダイナミックな構造と機能の変化を誘起される2017
- Author(s)
  大熊芳明、中村考秀、加藤大騎、鈴木吾大、松本靖彦、田中亜紀、大矢禎一、関水和久
- Organizer
  ConBio2017(第40回日本分子生物学会年会、第90回日本生化学会大会)
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子による転写開始から伸長への移行の制御機構解析2017
- Author(s)
  福岡瑞希、田中亜紀、平山翼、廣瀬豊、大熊芳明
- Organizer
  RNAミーティング2017
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] TLR9活性化の際のメディエーターキナーゼによる転写制御の解析2016
- Author(s)
  山本誠司，萩原衆子，堀内祥行，奥井文,　吉田徳幸，井上貴雄,　田中亜紀,　松久明生，廣瀬豊, 大熊芳明.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] Dynamic Switch　Mechanism of RNA polymerase II by General Transcription Factor TFIIE from Transcription Initiation to the Transition Step from Intiation to Elongation.2016
- Author(s)
  Ohkuma Y, Nakamura T, Akimoto Y, Fukuoka M, Hirose Y, Tanaka A
- Organizer
  The 39th Annual Meeting of the Molecular Biology Scociety of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 転写メディエーター複合体と神経細胞分化の関係2016
- Author(s)
  林裕人, 田中亜紀, 廣瀬豊, 大熊芳明.
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] Functional analysis of archaeal DNA-binding protein Sso7d2016
- Author(s)
  Nakamura T, Nomura N, Mitsumizu H, Hirose Y, Tanaka A, Ohkuma Y.
- Organizer
  The First International Symposium on Toyama-Asia-Africa Pharmaceutical Network
- Place of Presentation
  Toyama
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子TFIIEによる転写開始から伸長への移行の制御機構解析2016
- Author(s)
  中村考秀, 田中亜紀, 福岡瑞希,廣瀬豊,大熊芳明.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] メディエーター複合体と転写因子BRD4との機能的関連性の検討2015
- Author(s)
  林裕人、田中亜紀、廣瀬豊、田渕明子、大熊芳明.
- Organizer
  第33回日本生化学会北陸支部例会
- Place of Presentation
  富山
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] ヒトメディエーター複合体hMED17サブユニットによる転写制御とDNA損傷修復機能の解明2015
- Author(s)
  菊地祐子, 西谷紗織, 梅村啓靖, 田中亜紀, 廣瀬豊, 菅澤薫, 大熊芳明
- Organizer
  BMB2015 第38回日本分子生物学会・第88回日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] CpGオリゴ核酸によるTLR9を介した転写制御機構の解析2015
- Author(s)
  山本誠司，萩原衆子，堀内祥行，奥井文，和仁翔太郎,　吉田徳幸，井上貴雄,　田中亜紀,　松久明生，廣瀬豊,　大熊芳明
- Organizer
  BMB2015 第38回日本分子生物学会・第88回日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子TFIIBとTFIIEによる転写開始の制御機構2015
- Author(s)
  中村考秀、田中亜紀、秋元勇亮、郭丹恵、大熊芳明
- Organizer
  BMB2015 第38回日本分子生物学会・第88回日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子TFIIEα winged helix領域の機能解析2015
- Author(s)
  田中亜紀、福岡瑞希、小林聡子、大熊芳明
- Organizer
  BMB2015 第38回日本分子生物学会・第88回日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子TFIIEによる転写開始と伸長の制御機構の解析2015
- Author(s)
  郭丹慧、保田幸子、廣瀬豊、田中亜紀、今中常雄、大熊芳明.
- Organizer
  第33回日本生化学会北陸支部例会
- Place of Presentation
  富山
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子TFIIEによる転写開始から伸長への移行の制御機構解析2015
- Author(s)
  中村考秀, 田中亜紀, 廣瀬豊,大熊芳明
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 転写コファクターPC4と基本転写因子TFIIEのβサブユニットとの協調的な働き2015
- Author(s)
  秋元勇亮, 山本誠司, 飯田智, 田中亜紀, 廣瀬豊, 大熊芳明
- Organizer
  BMB2015 第38回日本分子生物学会・第88回日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K18861
[Presentation] 基本転写因子TFIIEとそれと相互作用する複合体の研究2010
- Author(s)
  田中亜紀
- Organizer
  平成22年度ターゲットタンパク成果発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790066
[Presentation] 基本転写因子TFIIEの機能ドメインの解析2010
- Author(s)
  田中亜紀
- Organizer
  BMB2010 第33回日本分子生物学会・第83回日本生化学会合同年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790066
[Presentation] 基本転写因子TFIIEの機能ドメインの解析2010
- Author(s)
  田中亜紀
- Organizer
  BMB2010 第33回日本分子生物学会・第83回日本生化学会合同年会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-21790066
[Presentation] Mediator MED15 and general transcription factor TFIIE interact to regulate RNA polymerase II transcription2009
- Author(s)
  Nakatsubo, T., Tanaka, A., Tsutsui, T., Mizuki, F., Ohkuma, Y
- Organizer
  The 2009 CSH Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] 基本転写因子TFIIEの機能ドメインの解析2009
- Author(s)
  田中亜紀
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-21790066
[Presentation] 基本転写因子TFIIEによる2種のRNAポリメラーゼIICTDキナーゼ複合体の制御. シンポジウム1S14pタンパク質修飾による遺伝子発現制御のクロストーク2009
- Author(s)
  大熊芳明, 中坪拓也, 後藤さやか, 筒井大気, 田中亜紀
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional study on novel Mediator subunit CDK11 in transcriptional regulation2008
- Author(s)
  Tsutsui, T., Umemura, H., Tanaka, A., Mizuki, F., Hirose, Y., Ohkuma, Y
- Organizer
  8th EMBL Transcription Meeting
- Place of Presentation
  EMBL, Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional study of novel Mediator kinase subunit CDK11 in transcriptional regulation2008
- Author(s)
  Tsutsui T., Umemura H., Tanaka A., Mizuki F., Hirose Y., Ohkuma Y
- Organizer
  The 21st Naito Conference on Nuclear Dynamics and RNA [I]
- Place of Presentation
  Yatsugatake Royal Hotel, Yamanashi, Japan
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] メディエーター複合体の新規キナーゼサブユニットの機能解析2008
- Author(s)
  梅村啓靖, 筒井大気, 田中亜紀, 廣瀬豊, 大熊芳明
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Specific interaction of TFIIEα acidic domain with TFIIH p62 PH domain in regulation of initiation transcription2008
- Author(s)
  Tanaka, A., Mizuta, S., Takazawa, M., Okuda, M., Nishimura, Y., Ohkuma, Y
- Organizer
  8th EMBL Transcription Meeting
- Place of Presentation
  EMBL, Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional studies on TFIIE and its mediated changes of RNA polymerase II in association with TFIIH and Mediator2007
- Author(s)
  Nakatsubo, T., Goto, S., Iida, Y., Tanaka, A., Ohkuma, Y
- Organizer
  10th Cold Spring Harbor Meeting on Cancer Cells: mechanisms of eukaryotic transcription
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] ヒトメディエーター複合体のキナーゼサブユニットCDK8は転写活性化を正に制御する2007
- Author(s)
  大熊芳明, 古元義, 田中亜紀, 花岡文雄
- Organizer
  日本薬学会第127年会シンポジウム「核内情報受容から遺伝子発現への機構-その分子レベルでのアプローチ」
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] hCDK8, a kinase subunit of human Mediator complex, plays a positive role in transcription2007
- Author(s)
  Umemura, H., Tsutsui, T., Nakatsubo, T., Tanaka, A., Hirose, Y., Ohkuma, Y
- Organizer
  10th Cold Spring Harbor Meeting on Cancer Cells
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] 転写メディエーターから基本転写装置へのシグナリング2007
- Author(s)
  田中亜紀, 古元義, 廣瀬豊, 花岡文雄, 大熊芳明
- Organizer
  BMB2007ワークショップ「遺伝子発現に向けた核内シグナリング」
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] The winged helix regions of human TFIIE are essential for transcription of RNA polymerase II2006
- Author(s)
  Tanaka, A., Watanabe, T., Hanaoka, F., Ohkuma, Y
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] A kinase subunit of human Mediator complex CDK8 plays a positive role in transcription2006
- Author(s)
  Furumoto, T., Tanaka, A., Malik, S., Roeder, R.G., Hanaoka, F., Ohkuma, Y
- Organizer
  7th EMBL Transcription Meeting
- Place of Presentation
  Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional studies of human Mediator subunit Med18/p28b2005
- Author(s)
  Furumoto, T., Tanaka, A., Malik, S., Ito, M., Roeder, R.G., Hanaoka, F., Ohkuma, Y
- Organizer
  9th Cold Spring Harbor Meeting on Cancer Cells: mechanisms of eukaryotic transcription
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] TFIIE induces conformational and functional changes in RNA polymerase II during transcription initiation2005
- Author(s)
  Hayashi, K., Watanabe, T., Tanaka, A., Furumoto, T., Sato-Tsuchiya, C., Yokoi, M., Hanaoka, F., Ohkuma, Y
- Organizer
  9th Cold Spring Harbor Meeting on Cancer Cells: mechanisms of eukaryotic transcription
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] Functional elucidations of the subdomains of the small subunit of TFIIE2005
- Author(s)
  Tanaka, A., Hanaoka, F., Ohkuma, Y
- Organizer
  9th Cold Spring Harbor Meeting on Cancer Cells: mechanisms of eukaryotic transcription
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17054022
[Presentation] 真核生物細胞核内の遺伝子発現ネットワーク:基本転写因子TFIIEは転写のスイッチである2005
- Author(s)
  林和洋、田中亜紀、古元義、佐藤-土屋千晶、花岡文雄、大熊芳明
- Organizer
  第28回日本分子生物学会年会, ワークショップ「蛋白質・核酸の修飾による転写制御を中心とした核内クロストーク」
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17054022

1. HIROSE Yutaka (00218851)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. OHKUMA Yoshiaki (70192515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
3. 高野克彦 (50293303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. INOUE Taskao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 広瀬豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
6. 伊藤敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 吉田徳幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 久武幸司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 菅澤薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Aki 田中 亜紀

TANAKA Aki 田中 亜紀

田中 亜紀 タナカ アキ

Research Projects

Research Products

Co-Researchers

基本転写因子によるRNAポリメラーゼIIの構造変換の分子機構の解析Principal InvestigatorOngoing

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Transcriptional regulatory mechanism of the RNA polymerase II initiation complex by the chromatin remodeling complexPrincipal Investigator

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Molecular mechanism of apoptotic pathway through the tumor suppressor protein p53 approached from gene expression controlPrincipal Investigator

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Unified crosstalk of signal transduction, chromatin regulation, and RNA processing by transcription complexes

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[Journal Article] Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-kappaB and C/EBPbeta on stimulation of Toll-like receptor 9.2017

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[Journal Article] Association of the winged helix motif of the TFIIEα subunit of TFIIE with either the TFIIEβ subunit or TFIIB distinguishes its functions in transcription.2015

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[Journal Article] Human Mediator MED17 Subunit Plays Essential Roles in Gene Regulation by Associating with both Transcription and DNA Repair Machineries.2015

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[Journal Article] The central forkhead domain of the small subunit of TFIIE plays a primary role in double-stranded DNA binding at transcription initiation2009

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[Journal Article] Central forkhead domain of human TFIIE beta plays a primary role in binding double-stranded DNA at transcription initiation.2009

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[Journal Article] The central forkhead domain of the small subunit of TFIIE plays a primaryrole in double-stranded DNA binding at transcription initiation.2009

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[Journal Article] The central forkhead domain of the small subunit of TFIIE plays a primary role in double-stranded DNA binding at transcription initiation2009

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[Journal Article] Human Mediator Kinase Subunit CDK11 Plays a Negative Role in Viral Activator VP16-dependent Transcription2008

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[Journal Article] Structural insight into the TFIIE/TFIIH: TFIIE and p53 share the binding region on TFIIH2008

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[Journal Article] A kinase subunit of the human Mediator complex, CDK8, positively regulates transcriptional activation2007

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[Journal Article] Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation2005

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[Journal Article] Structural insights into the asymmetric effects of zinc-ligand cysteine mutations in the novel zinc ribbon domain of human TFIIEα for transcription2005

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Tanaka Aki 田中亜紀

TANAKA Aki 田中亜紀

田中亜紀タナカアキ

[Presentation] Dynamic Switch　Mechanism of RNA polymerase II by General Transcription Factor TFIIE from Transcription Initiation to the Transition Step from Intiation to Elongation.2016