Koga Nobuyasu 古賀信康

… Alternative Names

Researcher Number	50432571
Other IDs
Affiliation (Current)	2021: 大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 准教授 2015 – 2017: 分子科学研究所, 協奏分子システム研究センター, 准教授
Review Section/Research Field	Principal Investigator Biophysics Except Principal Investigator Complex systems / Basic Section 43020:Structural biochemistry-related
Keywords	Principal Investigator タンパク質分子デザイン / 分子モーター / F1-ATPase / 構造変化 / P-loop / 分子動力学シミュレーション / １分子回転計測実験 / 改造 / 分子シミュレーション / 計算機デザイン … More Except Principal Investigator タンパク質デザイン / 生物分子モーター / DNAナノテクノロジー / ATP加水分解酵素 / タンパク質 / 合理的設計 / 合理的デザイン / バイオインフォマティクス / 合理デザイン Less

物理的に設計可能な蛋白質フォールド空間の解明：理論と実験的検証Ongoing
- Principal Investigator
  
  千見寺浄慈
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Nagoya University
生体発動分子の創成：自然界の生体分子の改造とゼロからの設計Ongoing
- Principal Investigator
  
  古田健也
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  National Institute of Information and Communications Technology
Understanding of the mechanisms of F1-ATPase by redesigning beta-subunit's P-loopPrincipal Investigator
- Principal Investigator
  
  KOGA Nobuyasu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
  Institute for Molecular Science

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 実験医学2019年11月号　p.3089‐3095「合理デザインによる新規タンパク質の創出：現状とその可能性」2019
- Author(s)
  小杉貴洋、古賀理恵、古賀信康
- Total Pages
  147
- Publisher
  羊土社
- ISBN
  9784758125253
- Data Source
  KAKENHI-PLANNED-18H05420
[Book] 「化学」計算機でゼロからタンパク質をデザイン ―望みのタンパク質分子のテーラーメイド創出を目指して2016
- Author(s)
  古賀理恵, 古賀信康
- Total Pages
  80
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-15H05592
[Journal Article] Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein2019
- Author(s)
  Basak Sujit、Nobrega R. Paul、Tavella Davide、Deveau Laura M.、Koga Nobuyasu、Tatsumi-Koga Rie、Baker David、Massi Francesca、Matthews C. Robert
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Pages: 6806-6811
- DOI
  10.1073/pnas.1818744116
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05420
[Journal Article] Consistency principle for protein design2019
- Author(s)
  Koga Rie、Koga Nobuyasu
- Journal Title
  
  BIOPHYSICS
  
  Volume: 16 Issue: 0 Pages: 304-309
- DOI
  10.2142/biophysico.16.0_304
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05420
[Journal Article] ShadowR : a novel chromoprotein with reduced non-specific binding and improved expression in living cells2019
- Author(s)
  Murakoshi H., Horiuchi H., Kosugi T., Onda M., Sato A., Koga N., Nabekura J.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 12072-12072
- DOI
  10.1038/s41598-019-48604-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14825, KAKENHI-PUBLICLY-18H04748, KAKENHI-PUBLICLY-19H05434, KAKENHI-PROJECT-18H02708, KAKENHI-PROJECT-18K19382, KAKENHI-PLANNED-18H05420, KAKENHI-PROJECT-16H06280
[Presentation] EXPLORATION OF NOVEL ALPHA-BETA PROTEIN FOLDS BY DE NOVO DESIGN2020
- Author(s)
  S. Minami, N. Kobayashi, T. Sugiki, R. Koga, G. Chikenji, N. Koga
- Organizer
  The Biophysical Society Annual Meeting 2020
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] DESIGN OF GLOBIN-LIKE COMPLICATED FOLDS2020
- Author(s)
  K. Sakuma, N. Kobayashi, T. Sugiki, K. Suzuki, N. Kobayashi, T. Kosugi, T. Murata, R. Koga, N. Koga
- Organizer
  The Biophysical Society Annual Meeting 2020
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] Toward creation of artificial proteins self-assembling into diverse symmetric structures: computational design and experimental2020
- Author(s)
  N. Kobayashi, N. Koga
- Organizer
  The 1st International Symposium on Molecular Engine
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] De novo design of ATP-binding protein with two-domain structure2019
- Author(s)
  H. Yamada, K. Nakamura, T. Kosugi, N. Koga
- Organizer
  2nd Tokyo ATPase Workshop
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] Exploration of novel alpha-beta protein folds by de novo design2019
- Author(s)
  S. Minami, R. Koga, G. Chikenji, T. Sugiki, N. Kobayashi
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H03166
[Presentation] Rotation of the engineered F1-ATPase with non-catalytic α-type P-loops2018
- Author(s)
  上野博史, 古賀理恵、政池知子, 野地博行, 古賀信康
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] ヒンジ領域を非触媒型に置換した触媒サブユニットをもつ F1-ATPase の回転トルクと反応速度2018
- Author(s)
  佐藤友保, 上野博史, 林久美子, 古賀理恵, 古賀信康, 野地博行, 政池知子
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] Toward generation of de novo designed protein structure library2018
- Author(s)
  N. Koga
- Organizer
  Frontier Bio-organization forum 2018
- Invited
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] DBTL in protein design2018
- Author(s)
  N. Koga
- Organizer
  Trends in Computational Molecular Biology
- Invited
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] Impact of the sequence difference of P-loop on the conformational changes of F1-ATPase2018
- Author(s)
  R. Koga, H. Ueno, T. Masaike, H. Noji, N. Koga
- Organizer
  The 79th Okazaki Conference: Synthetic, Biological, and Hybrid Molecular Engines
- Data Source
  KAKENHI-PLANNED-18H05420
[Presentation] F1-ATPaseの構造変化にα とβ のP-loop配列の違いが及ぼす影響2018
- Author(s)
  古賀理恵、上野博史, 政池知子, 野地博行, 古賀信康
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] Impact of the sequence difference of P-loop on the conformational changes of F1-ATPase2018
- Author(s)
  Rie Koga, Hiroshi Ueno, Tomoko Masaike, Hiroyuki Noji and Nobuyasu Koga
- Organizer
  The 79th Okazaki Conference: Synthetic, Biological, and Hybrid Molecular Engines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] Rotation of the engineered F1-ATPase with α-type P-loop on catalytic β subunit2017
- Author(s)
  上野　博史、古賀　理恵、政池　知子、古賀　信康、野地　博行
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] 回転分子モーターF1-ATPaseの構造変化メカニズムの解明に向けて2017
- Author(s)
  古賀　理恵、上野　博史、政池　知子、野地　博行、古賀　信康
- Organizer
  第１７回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] タンパク質分子の合理設計2016
- Author(s)
  古賀信康
- Organizer
  東京大学第４回応化談話会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-12-18
- Invited
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] Synthetic approach for understanding molecular motors2016
- Author(s)
  古賀信康
- Organizer
  統合バイオ・リトリート
- Place of Presentation
  三河リゾートサンクス（愛知県西尾市）
- Year and Date
  2016-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] 分子モーターの合理デザイン：ゼロからの創製と自然界のタンパク質の改造2016
- Author(s)
  古賀信康
- Organizer
  分子モーター討論会
- Place of Presentation
  大阪大学蛋白質研究所（大阪府吹田市）
- Year and Date
  2016-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] A synthetic approach to understanding protein molecules2015
- Author(s)
  Nobuyasu Koga
- Organizer
  JST CREST-PRESTO joint international symposium
- Place of Presentation
  The University of Tokyo, Japan
- Year and Date
  2015-11-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] 主鎖二面角パターンによるαβ型タンパク質構造のデザイン2015
- Author(s)
  Yu-Ru Lin, 古賀理恵, Gaohua Liu, Gaetano T. Montelione, David Baker, 古賀信康
- Organizer
  日本生物物理学会
- Place of Presentation
  金沢大学角間キャンパス (石川県金沢市）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15H05592
[Presentation] Design of ideal protein structures2015
- Author(s)
  Nobuyasu Koga
- Organizer
  The 15th KIAS Conference on Protein Structure and Function, Korea Institute for Advanced Study
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-09-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05592

1. 古田健也 (40571831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 小杉貴洋 (00771388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 千見寺浄慈 (10420366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Koga Rie

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. Ueno Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. Noji Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. Masaike Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 堀内浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 村越秀治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 鍋倉淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koga Nobuyasu 古賀 信康

KOGA Nobuyasu 古賀 信康

Research Projects

Research Products

Co-Researchers

物理的に設計可能な蛋白質フォールド空間の解明：理論と実験的検証Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体発動分子の創成：自然界の生体分子の改造とゼロからの設計Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding of the mechanisms of F1-ATPase by redesigning beta-subunit's P-loopPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学2019年11月号 p.3089‐3095「合理デザインによる新規タンパク質の創出：現状とその可能性」2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 「化学」計算機でゼロからタンパク質をデザイン ―望みのタンパク質分子のテーラーメイド創出を目指して2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Consistency principle for protein design2019

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] ShadowR : a novel chromoprotein with reduced non-specific binding and improved expression in living cells2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] EXPLORATION OF NOVEL ALPHA-BETA PROTEIN FOLDS BY DE NOVO DESIGN2020

Author(s)

Organizer

Data Source

[Presentation] DESIGN OF GLOBIN-LIKE COMPLICATED FOLDS2020

Author(s)

Organizer

Data Source

[Presentation] Toward creation of artificial proteins self-assembling into diverse symmetric structures: computational design and experimental2020

Author(s)

Organizer

Data Source

[Presentation] De novo design of ATP-binding protein with two-domain structure2019

Author(s)

Organizer

Data Source

[Presentation] Exploration of novel alpha-beta protein folds by de novo design2019

Author(s)

Organizer

Data Source

[Presentation] Rotation of the engineered F1-ATPase with non-catalytic α-type P-loops2018

Author(s)

Organizer

Data Source

[Presentation] ヒンジ領域を非触媒型に置換した触媒サブユニットをもつ F1-ATPase の回転トルクと反応速度2018

Author(s)

Organizer

Data Source

[Presentation] Toward generation of de novo designed protein structure library2018

Koga Nobuyasu 古賀信康

KOGA Nobuyasu 古賀信康

[Book] 実験医学2019年11月号　p.3089‐3095「合理デザインによる新規タンパク質の創出：現状とその可能性」2019