MATSUZAKI Hitomi 松崎仁美

Researcher Number	50436242
Other IDs
Affiliation (Current)	2021: 筑波大学, 生命環境系, 助教
Affiliation (based on the past Project Information) *help	2014 – 2020: 筑波大学, 生命環境系, 助教 2019: 筑波大学, 生命環境科学研究科(系), 助教
Review Section/Research Field	Principal Investigator Genetics/Chromosome dynamics / Biological Sciences / Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator ゲノム刷り込み / エピジェネティクス / DNAメチル化 / 遺伝子 / 発現制御 / 非対称性DNAメチル化

哺乳類の正常発生を支える非対称性DNAメチル化維持機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  松崎仁美
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
哺乳類の世代間エピジェネティックマーク変換機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  松崎仁美
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  University of Tsukuba
受精後刷り込みメチル化によるゲノム機能制御の普遍性とその進化的意味の検証Principal InvestigatorOngoing
- Principal Investigator
  
  松崎仁美
- Project Period (FY)
  2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  University of Tsukuba
Search for germline epigenetic information that induces post-fertilization imprinted methylationPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Hitomi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  University of Tsukuba
Molecular mechanisms of epigenetic regulation at the mouse imprinted locusPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Hitomi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  University of Tsukuba

All 2020 2019 2018 2016 2015 Other

All Journal Article Presentation

[Journal Article] Recapitulation of gametic DNA methylation and its post-fertilization maintenance with reassembled DNA elements at the mouse Igf2/H19 locus2020
- Author(s)
  Matsuzaki, H., Kuramochi, D., Okamura, E., Hirakawa, K., Ushiki, A., and Tanimoto, K.
- Journal Title
  
  Epigenetics & Chromatin
  
  Volume: 13 Pages: 2-2
- DOI
  10.1186/s13072-019-0326-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05012
[Journal Article] Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice2018
- Author(s)
  Matsuzaki, H,. Okamura, E., Kuramochi, D., Ushiki, A., Hirakawa, K., Fukamizu, A., and Tanimoto, K.
- Journal Title
  
  Epigenetics & Chromatin
  
  Volume: 11 Pages: 36-36
- DOI
  10.1186/s13072-018-0207-z
- NAID
  120006501410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05012, KAKENHI-PROJECT-26292189
[Journal Article] De novo DNA methylation through the 5′-segment of the H19 ICR maintains its imprint during early embryogenesis2015
- Author(s)
  Matsuzaki, H., Okamura, E., Takahashi, T., Ushiki, A., Nakamura, T., Nakano, T., Hata, K., Fukamizu, A., and Tanimoto, K.
- Journal Title
  
  Development.
  
  Volume: 142 Pages: 3833-3844
- DOI
  10.1242/dev.126003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26840113, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112006, KAKENHI-PUBLICLY-26112503, KAKENHI-PROJECT-26640063, KAKENHI-PROJECT-25291053, KAKENHI-PROJECT-26292189, KAKENHI-PROJECT-15H02509
[Presentation] YACトランスジェニック・マウスを用いたヒトH19-ICR刷り込みメチル化メカニズムの検証2019
- Author(s)
  平川勝彦、松崎仁美、谷本啓司
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H05012
[Presentation] Reconstituted H19 ICR sequence with identified cis elements is capable of maintaining genomic imprinting in knock-in mouse2019
- Author(s)
  Matsuzaki, H., Kuramochi, D., Hirakawa, K., and Tanimoto, K.
- Organizer
  33rd International Mammalian Genome Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05012
[Presentation] マウスのゲノム刷り込み制御におけるH19-ICR配列反転の効果2019
- Author(s)
  宮嶋優、谷本啓司、松崎仁美
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H05012
[Presentation] Test for imprinted DNA methylation activity of the human H19-ICR in YAC transgenic mice by adopting a transgene co-placement strategy2019
- Author(s)
  Hirakawa, K., Matsuzaki, H., and Tanimoto, K
- Organizer
  The 15th Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05012
[Presentation] H19-ICR反転によるH19遺伝子転写制御機構のin vivo解析2018
- Author(s)
  宮嶋優、谷本啓司、松崎仁美
- Organizer
  第12回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-17H05012
[Presentation] Imprinted gene expression can be reconstituted by synthetic DNA fragment composed of specified cis regulatory elements from the H19 ICR2018
- Author(s)
  Matsuzaki, H., Kuramochi, D., Hirakawa, K., and Tanimoto, K.
- Organizer
  Keystone Symposia (Gene Control in Development and Disease)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] In vivo analysis of H19 gene transcriptional mechanism by inversion of the H19 imprinting control region2018
- Author(s)
  Matsuzaki, H., Miyajima, Y., and Tanimoto, K
- Organizer
  32nd International Mammalian Genome Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05012
[Presentation] Imprinted DNA methylation status can be reconstituted by combining activity of distinct H19 ICR elements in mice2016
- Author(s)
  松崎仁美、谷本啓司
- Organizer
  Mouse Genetics 2016 at The Allied Genetics Conference 2016
- Place of Presentation
  Orlando (USA)
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] マウスH19 ICR上流配列を介したアリル特異的DNAメチル化の検証2016
- Author(s)
  松崎仁美、倉持大地、谷本啓司
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] 5’-segment of the H19 ICR confers ability to acquire post-fertilization allele-specific DNA methylation to artificial DNA sequences2016
- Author(s)
  Matsuzaki, H. and Tanimoto, K.
- Organizer
  International Symposium on Epigenome Dynamics and Regulation in Germ Cells
- Place of Presentation
  京都大学（京都府・京都市）
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] 受精後アリル特異的de novo DNAメチル化によるゲノム刷り込み制御2016
- Author(s)
  松崎仁美
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] マウスにおける再構築刷り込みメチル化配列の活性の検証2015
- Author(s)
  松崎仁美、倉持大地、谷本啓司
- Organizer
  第38回日本分子生物学会年会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] 刷り込みメチル化配列の再構築2015
- Author(s)
  松崎仁美、谷本啓司
- Organizer
  第9回日本エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター一橋講堂（東京都・千代田区）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] De novo DNA methylation mediated by 5' portion of the H19 ICR is essential for maintaining its methylation imprint during early embryogenesis in mice2015
- Author(s)
  Tanimoto, K., Matsuzaki, H., Okamura, E., Ushiki, A., and Takahashi, T.
- Organizer
  Mouse Molecular Genetics 2015
- Place of Presentation
  Cambridge (UK)
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] マウスH19 ICRにおける受精後アリル特異的DNAメチル化活性の解析
- Author(s)
  松崎仁美、岡村永一、牛木亜季、高橋拓也、谷本啓司
- Organizer
  第8回日本エピジェネティクス研究会年会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都・文京区）
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] Igf2/H19刷り込み遺伝子座における受精後アリル特異的DNAメチル化活性の解析
- Author(s)
  松崎仁美、岡村永一、牛木亜季、高橋拓也、谷本啓司
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26840113
[Presentation] A role for postfertilization, allele-specific DNA methylation activity in maintaining the imprinted H19 ICR methylation
- Author(s)
  Matsuzaki, H., Okamura, E., Ushiki, A., Takahashi, T., Tanimoto, K.
- Organizer
  Keystone Symposia (DNA methylation)
- Place of Presentation
  Keystone (アメリカ合衆国)
- Year and Date
  2015-03-29 – 2015-04-03
- Data Source
  KAKENHI-PROJECT-26840113

1. NAKAMURA Toshinobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 谷本啓司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 仲野徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUZAKI Hitomi 松崎 仁美

Research Projects

Research Products

Co-Researchers

哺乳類の正常発生を支える非対称性DNAメチル化維持機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

哺乳類の世代間エピジェネティックマーク変換機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

受精後刷り込みメチル化によるゲノム機能制御の普遍性とその進化的意味の検証Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for germline epigenetic information that induces post-fertilization imprinted methylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of epigenetic regulation at the mouse imprinted locusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Recapitulation of gametic DNA methylation and its post-fertilization maintenance with reassembled DNA elements at the mouse Igf2/H19 locus2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] De novo DNA methylation through the 5′-segment of the H19 ICR maintains its imprint during early embryogenesis2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] YACトランスジェニック・マウスを用いたヒトH19-ICR刷り込みメチル化メカニズムの検証2019

Author(s)

Organizer

Data Source

[Presentation] Reconstituted H19 ICR sequence with identified cis elements is capable of maintaining genomic imprinting in knock-in mouse2019

Author(s)

Organizer

Data Source

[Presentation] マウスのゲノム刷り込み制御におけるH19-ICR配列反転の効果2019

Author(s)

Organizer

Data Source

[Presentation] Test for imprinted DNA methylation activity of the human H19-ICR in YAC transgenic mice by adopting a transgene co-placement strategy2019

Author(s)

Organizer

Data Source

[Presentation] H19-ICR反転によるH19遺伝子転写制御機構のin vivo解析2018

Author(s)

Organizer

Data Source

[Presentation] Imprinted gene expression can be reconstituted by synthetic DNA fragment composed of specified cis regulatory elements from the H19 ICR2018

Author(s)

Organizer

Data Source

[Presentation] In vivo analysis of H19 gene transcriptional mechanism by inversion of the H19 imprinting control region2018

Author(s)

Organizer

Data Source

[Presentation] Imprinted DNA methylation status can be reconstituted by combining activity of distinct H19 ICR elements in mice2016

Author(s)

MATSUZAKI Hitomi 松崎仁美