Ishiyama Kohei 石山宏平

… Alternative Names

ISHIYAMA Kohei 石山宏平

Less

Researcher Number	50437589
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 愛知医科大学, 医学部, 准教授 2017 – 2018: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他 2016: 広島大学, 病院(医), 病院助教 2013 – 2015: 広島大学, 大学病院, 病院助教 2012: 広島大学, 医歯薬保健学研究院, 特任助教 … More 2011: 広島大学, 医歯(薬)学総合研究科, 特任助教 2007: Hiroshima University, Hospital, Assistant Professor 2006: 広島大学, 病院・医員 Less
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 56030:Urology-related / General surgery
Keywords	Principal Investigator 膵島移植 / 間葉系幹細胞 / NK細胞 / 免疫制御 / 免疫学 / 移植 / 糖尿病 / 肝臓内免疫 / プロスタグランジン / 1型糖尿病 / 免疫 / 肝臓免疫 / NK 細胞 … More Except Principal Investigator … More エピトープ / 抗原提示 / CD4 T-cell / 免疫寛容 / 臓器移植 / アロ応答 / 濾胞性T細胞 / single cell / 樹状細胞 / ヒト免疫 / 移植免疫 / ウイルス感 / ウイルス感染 / 慢性抗体関連型拒絶反応 / パラトープ / 免疫制御 / 腎移植 / 移植・再生医療 / self-recognition system / T cell immune response / macrophage / xenotransplantation / 自己認識機構 / T細胞性免疫応答 / マクロファージ / 異種移植 / 細胞免疫療法 / 肝臓癌 / NK細胞 Less

ヒト乳歯歯髄幹細胞を用いた膵島オルガノイドによる画期的膵島移植プロトコールの開発Principal Investigator
- Principal Investigator
  
  石山宏平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Aichi Medical University
Identification of Indirect Alloreactive T-Cells and Application to Monitoring of anti-Donor Antibody Sensing
- Principal Investigator
  
  IWASAKI KENTA
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Aichi Medical University
Development of control method of immune response after multiple islet transplantation in anticipation of ES/iPS cell transplantationPrincipal Investigator
- Principal Investigator
  
  Ishiyama Kohei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Aichi Medical University
From treatment to prevention: development of innovative immune regulation based on epitope/paratope analysis
- Principal Investigator
  
  Kobayashi Takaaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Aichi Medical University
Elucidation of intrahepatic immunization and development of intrahepatic immune control after islet transplantationPrincipal Investigator
- Principal Investigator
  
  Ishiyama Kohei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
  Hiroshima University
The suppressive mechanism of liver immune reactivity after islet transplantation by mesenchymal stem cellsPrincipal Investigator
- Principal Investigator
  
  Ishiyama Kohei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Generation of TRAIL positive NK cells from hematopoietic stem cells / iPS cells in vitro for anti-HCC immunotherapy
- Principal Investigator
  
  TANAKA Yuka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Regulation of cytotoxic activity of liver NK cells against islet graftPrincipal Investigator
- Principal Investigator
  
  ISHIYAMA Kohei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
Regulation of innate and adaptive immune responses in xenotransplantation by modulating CD47sirp α signaling
- Principal Investigator
  
  OHDAN Hideki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University

All 2024 2023 2022 2021 2020 2019 2017 2014 2013 2012 2011 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Estimation of Sensitization Status in Renal Transplant Recipients by Assessing Indirect Pathway CD4+ T Cell Response to Donor Cell-pulsed Dendritic Cell2023
- Author(s)
  Kenta Iwasaki、Toshihide Tomosugi、Takashi Sekiya、Shintaro Sakamoto、Yuko Miwa、Manabu Okada、Takahisa Hiramitsu、Norihiko Goto、Shunji Narumi、Yoshihiko Watarai、Mai Okumura、Satoshi Ashimine、Kohei Ishiyama、Ezzelarab Mohamed B.、Takaaki Kobayashi
- Journal Title
  
  Transplantation
  
  Volume: 107 Issue: 5 Pages: 1079-1088
- DOI
  10.1097/tp.0000000000004491
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03818, KAKENHI-PROJECT-21H02756, KAKENHI-PROJECT-20K20608, KAKENHI-PROJECT-21K19393, KAKENHI-PROJECT-21K09385
[Journal Article] Improved detection of donor-specific HLA-class II antibody in kidney transplant recipients by modified immunocomplex capture fluorescence analysis2021
- Author(s)
  Shimabukuro Shuichi、Iwasaki Kenta、Kawai Shintaro、Shirouzu Takayuki、Miwa Yuko、Iida Yusuke、Nakajima Fumiaki、Horimi Kosei、Matsuoka Yutaka、Ashimine Satoshi、Ishiyama Kohei、Kobayashi Takaaki
- Journal Title
  
  Transplant Immunology
  
  Volume: 67 Pages: 101418-101418
- DOI
  10.1016/j.trim.2021.101418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09680, KAKENHI-PROJECT-20H03818, KAKENHI-PROJECT-20K20608
[Journal Article] Cotransplantation of preactivated mesenchymal stem cells improves intraportal engraftment of islets by inhibiting liver natural killer cells in mice2019
- Author(s)
  Ishida Nobuki、Ishiyama Kohei、Saeki Yoshihiro、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 19 Issue: 10 Pages: 1-14
- DOI
  10.1111/ajt.15347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10427, KAKENHI-PROJECT-20K20391
[Journal Article] Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation2019
- Author(s)
  Saeki Y.、Ishiyama K.、Ishida N.、Tanaka Y.、Ohdan H.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-018-37395-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10427
[Journal Article] Role of Natural Killer Cells in the Innate Immune System After Intraportal Islet Transplantation in Mice.2017
- Author(s)
  Saeki Y, Ishiyama K, Ishida N, Tanaka Y, Ohdan H
- Journal Title
  
  Transplant Proc
  
  Volume: 49(1) Issue: 1 Pages: 139-144
- DOI
  10.1016/j.transproceed.2016.10.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10427
[Journal Article] Tho persistent elimination of B cells responding to blood group A carbohydrates by synthetic group A carbohydrates and B-1 cell differentiation blockade : novel concept in preventing antibody-mediated rejection in ABO-incompatible transplantation2007
- Author(s)
  H.,Ohdan, W., Zhou, K., Ishiyama, Y., Tanaka, K., Idc, T., Asahara
- Journal Title
  
  Blood 15, 110(13)
  
  Pages: 4567-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Journal Article] Liver sinusoidal endothelial cells that endocytose allogeneic cells suppress T cells with indirect allospecificity2006
- Author(s)
  D.,Tokita, M.,Shishida, H.,Ohdan, T.,Onoe, H.,Hara, Y.,Tanaka, K.,Ishiyama, H.,Mitsuta, K.,Ide, K.,Arihiro, T.,Asahara
- Journal Title
  
  J Immunol 15, 177(6)
  
  Pages: 3615-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] 異種膵島移植を見据えたヒト脱落乳歯歯髄幹細胞による液性及び細胞性免疫制御の試み2024
- Author(s)
  石山宏平
- Organizer
  日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-23K08082
[Presentation] ヒト乳歯歯髄幹細胞を用いた膵島オルガノイドによる画期的膵島移植プロトコールの開発2023
- Author(s)
  石山宏平
- Organizer
  日本膵膵島移植学会
- Data Source
  KAKENHI-PROJECT-20K08999
[Presentation] 間葉系幹細胞の免疫抑制メカニズムの検証2023
- Author(s)
  石山宏平
- Organizer
  日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-23K08082
[Presentation] Indirect alloresponseを模倣したヒト樹状細胞によるドナー特異的T細胞解析2023
- Author(s)
  岩﨑研太1）、三輪祐子1）、雫真人2）、安次嶺聡2）、石山宏平2）、Xian Liu3）、山崎晶3）、小林孝彰2）
- Organizer
  第31回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-21K09385
[Presentation] T 細胞エピトープは妊娠感作後の de novo DQ/DR DSA 予測に有用2023
- Author(s)
  安次嶺聡、坂本慎太郎、雫真人、三輪祐子、岩﨑研太、鳴海俊治、渡井至彦、石山宏平、小林孝彰
- Organizer
  第56回日本臨床腎移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] DCを用いたCD4 T細胞培養系によるIndirect alloresponse評価2023
- Author(s)
  岩﨑研太1）、友杉俊英2）、関谷高史3）、三輪祐子1）、Mohamed B. Ezzelarab4）、Xiuyuan Lu 5)、山崎晶5)、雫真人1）、安次嶺聡1）、石山宏平1）、小林孝彰1）
- Organizer
  第59回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-21K09385
[Presentation] 樹状細胞を用いたindirect alloresponse検出系によるドナー特異的T細胞解析2023
- Author(s)
  岩﨑研太*, 三輪祐子, 安次嶺聡, 石山宏平, 小林孝彰
- Organizer
  第20回日本免疫治療学会
- Data Source
  KAKENHI-PROJECT-21K09385
[Presentation] 腎移植における水痘・帯状疱疹ウイルス（VZV）に対する細胞性免疫2022
- Author(s)
  三輪祐子、岩﨑研太、安次嶺聡、雫真人、石山宏平、小林孝彰
- Organizer
  第58回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] In silico DSA産生予測と、樹状細胞を用いたindirect alloresponse検出系による感作把握2022
- Author(s)
  岩﨑研太、友杉俊英、関谷高史、三輪祐子、石山宏平、安次嶺聡、 Mohamed B. Ezzelarab、Xiuyuan Lu、山崎晶、小林孝彰
- Organizer
  第58回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] Which is More Important for Predicting De Novo DSA Production, B Cell Epitope (EPLET) or T Cell Epitope (PIRCHE) Analysis ?2022
- Author(s)
  T. Kobayashi, T. Tomosugi, S. Sakamoto, S. Ashimine, K. Iwasaki, M. Niemann, E. Spierings, Y. Miwa{1}, M. Okumura, K. Ishiyama, A. Takeda, N. Goto, S. Narumi, Y. Watarai
- Organizer
  American Transplant Congress (ATC) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 樹状細胞を用いた間接アロ応答検出系による腎移植患者感作の把握2022
- Author(s)
  岩崎研太、友杉俊英、関谷高史、三輪裕子、石山宏平、安次嶺聡、Mohamed B. Ezzelarab、小林孝彰
- Organizer
  第30回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 膵島移植における活性型歯髄幹細胞を用いた免疫抑制療法の開発2022
- Author(s)
  石山宏平
- Organizer
  第49回日本膵・膵島移植学会
- Data Source
  KAKENHI-PROJECT-20K08999
[Presentation] 腎移植におけるBKウイルス制御のための分子免疫学モニタリング2022
- Author(s)
  三輪裕子、安次嶺聡、岩崎研太、岡田学、鳴海俊治、渡井至彦、雫真人、石山宏平、小林孝彰
- Organizer
  第30回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] Establishment of an In Vitro Assay to Evaluate Indirect T-cell Allo- Response Using Donor PBMC-Pulsed Dendritic Cells.2022
- Author(s)
  K. Iwasaki, T. Tomosugi, T. Sekiya, H. Hamana, Y. Miwa, K. Futamura, M. Okada, T. Hiramitsu, N. Goto, S. Narumi, Y. Watarai, H. Kishi, M. Okumura, S. Ashimine, K. Ishiyama, T. Kobayashi
- Organizer
  American Transplant Congress (ATC) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 拒絶反応制御を目的としたヒト乳歯歯髄幹細胞同時移植による膵島移植後の新しい免疫抑制法の開発2022
- Author(s)
  石山宏平
- Organizer
  日本移植学会
- Data Source
  KAKENHI-PROJECT-20K08999
[Presentation] 免疫グロブリン療法は間接アロ免疫応答を増強する？2022
- Author(s)
  雫真人、雫真人、岩﨑研太、岡田学、三輪裕子、安次嶺聡、石山宏平、小林孝彰
- Organizer
  第48回日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] ドナー感作歴をもつ腎移植レシピエントのde novo DSA産生予測にB細胞エピトープ解析とT細胞エピトープは有用か？2022
- Author(s)
  安次嶺聡、友杉俊英、坂本慎太郎、雫真人、岡田学、三輪裕子、岩崎研太、鳴海俊治、渡井至彦、石山宏平、小林孝彰
- Organizer
  第30回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 高用量アルブミン誘発酸化ストレス脆弱性に対する SGL2022
- Author(s)
  松岡直也、岩﨑研太、勝野敬之、姫野竜仁、速水智英、三輪裕子、雫真人、安次嶺聡、石山宏平、小林孝彰
- Organizer
  第48回日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] In silico と in vitro 解析における de novo DSA リスク評価2022
- Author(s)
  岩﨑研太、友杉俊英、関谷高史、三輪裕子、石山宏平、安次嶺聡、Mohamed B.Ezzelarab、Xiuyuan Lu、山崎晶、小林孝彰
- Organizer
  第48回日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 腎移植後の急性拒絶反応とBKウイルス血症はde novo DSA産生の契機となる2022
- Author(s)
  安次嶺聡、雫真人、三輪祐子、岩﨑研太、石山宏平、小林孝彰
- Organizer
  第58回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] de novo DSA早期診断のためのT細胞受容体レパトア解析2022
- Author(s)
  雫真人、安次嶺聡、石山宏平、三輪祐子、岩﨑研太、小林孝彰
- Organizer
  第58回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 経時的末梢血リンパ球モニタリングによる腎移植後DSA産生のバイオマーカー探索2021
- Author(s)
  田中一樹、岩﨑研太、奥村真衣、三輪祐子、安次嶺聡、石山宏平、細道一善、藤田直也、小林孝彰
- Organizer
  第29回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 愛知医科大学における免疫抑制プロトコール2021
- Author(s)
  石山宏平、堀見孔星、木下航平、三輪祐子、岩﨑研太、小林孝彰
- Organizer
  第54回日本臨床腎移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] Indirect allorecognition評価法の確立とモニタリングへの応用～次世代技術による免疫リスク評価の統合的アプローチへ向けた試み～2021
- Author(s)
  岩﨑研太、友杉俊英、田中一樹、浜名洋、三輪裕子、河野あゆみ、奥村真衣、安次嶺聡、石山宏平、岸裕幸、小林孝彰
- Organizer
  第57回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 腎移植におけるBKV再活性化リスク因子の探索2021
- Author(s)
  三輪裕子、安次嶺聡、岩﨑研太、奥村真衣、石山宏平、小林孝彰
- Organizer
  第57回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 愛知医科大学における腎移植後抗体関連型拒絶反応の診断と治療2021
- Author(s)
  安次嶺聡、友杉俊英、坂本慎太郎、奥村真衣、三輪祐子、岩﨑研太、石山宏平、小林孝彰
- Organizer
  第57回日本移植学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] Indirect allorecognition評価法の確立とモニタリングへの応用2021
- Author(s)
  岩﨑研太, 友杉俊英, 田中一樹, 浜名洋, 三輪祐子, 河野あゆみ, 奥村真衣, 安次嶺聡, 石山宏平, 岸裕幸, 小林孝彰
- Organizer
  移植学会
- Data Source
  KAKENHI-PROJECT-21K09385
[Presentation] ヒトDCを用いたIndirectアロ応答の検出2021
- Author(s)
  岩﨑研太, 友杉俊英, 関谷高史, 三輪祐子, 石山宏平, 安次嶺聡, 奥村真衣, 小林孝彰
- Organizer
  組織適合性学会
- Data Source
  KAKENHI-PROJECT-21K09385
[Presentation] ABO不適合生体腎移植ではHLAエピトープミスマッチ数の安全域の広さがde novo DSA産生抑制にはたらく2021
- Author(s)
  安次嶺聡、友杉俊英、坂本慎太郎、奥村真衣、岡田学、三輪祐子、岩﨑研太、鳴海俊治、渡井至彦、石山宏平、小林孝彰
- Organizer
  第29回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 膵島移植における活性化ヒト間葉系幹細胞を用いた免疫抑制療法の開発2021
- Author(s)
  石山宏平
- Organizer
  第47回日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-20K08999
[Presentation] 免疫順応・寛容を構築するグラフト内皮細胞におけるアロ免疫応答2021
- Author(s)
  岩﨑研太、三輪祐子、奥村真衣、安次嶺聡、石山宏平、村口篤、岸裕幸、浜名洋、小林孝彰
- Organizer
  第47回日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] ABO血液型不適合腎移植に起因する急性抗体関連型拒絶反応（ABMR）の移植前リスク評価におけるIgGサブクラスおよびC1qの潜在的価値2021
- Author(s)
  三輪祐子、岩﨑研太、岡田学、渡井至彦、岩瀬勇人、長坂隆治、奥村真衣、安次嶺聡、石山宏平、小林孝彰
- Organizer
  第29回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] ABO血液型不適合腎移植における抗体関連型拒絶反応(ABMR)の移植前リスク評価2020
- Author(s)
  三輪祐子，岩崎研太，岡田　学，友杉俊英，渡井至彦，堀見孔星，奥村真衣，木下航平，石山宏平，小林孝彰
- Organizer
  第56回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] 内皮細胞HLA-class II応答性de novo foxp3陽性CD4 T細胞のTreg機能解析2020
- Author(s)
  岩崎研太，三輪祐子，平光高久，岡田　学，鳴海俊治，渡井至彦，武田朝美，堀見孔星，松岡　裕，友杉俊英，奥村真衣，石山宏平，木下航平，打田和治，小林孝彰
- Organizer
  第56回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20H03818
[Presentation] Activation of liver resident DX5 negative NK cells after intraportal islet transplantation prevent the engraftment of secondary transplanted islets2017
- Author(s)
  Ishiyama K
- Organizer
  TSS 2017 15th transplantation science symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10427
[Presentation] 膵島移植後のInstant blood-mediated inflammatory reaction環境下における肝臓内Memory Natural Killer細胞の活性化機構の解明2014
- Author(s)
  石山宏平、佐伯吉弘、平田文宏、田中友加、大段秀樹
- Organizer
  日本膵・膵島移植研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] 間葉系幹細胞産生プロスタグランディン E2を介した肝臓内 NK 細胞活性抑制効果の検討2013
- Author(s)
  平田文宏、石山宏平、その他
- Organizer
  第40回日本膵・膵島移植研究会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] 膵島移植後グラフト傷害に対する肝臓内Memory Natural killer細胞の機能解析2013
- Author(s)
  佐伯吉弘、石山宏平、平田文宏、田中友加、大段秀樹
- Organizer
  日本消化器外科学会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] Unlicensed NK Cells Differentiated from CD34+ Hematopoietic Progenitor Cells Exhibit Anti-HCC and Anti-HCV Activity2013
- Author(s)
  Ryuichi Hotta, Yuka Tanaka, Seiichi Shimizu, Masahiro Ohira, Kohei Ishiyama, Nobuhiko Hiraga, Kazuaki Chayama, Hideki Ohdan
- Organizer
  American Transplant Congress2013
- Place of Presentation
  Seattle, America
- Data Source
  KAKENHI-PROJECT-24591880
[Presentation] Mesenchymal Stem Cells Suppress Cytotoxic Activity of Natural Killer Cells in Islet Cell2013
- Author(s)
  Yoshihiro Saeki, Kohei Ishiyama, et al
- Organizer
  Transplantation, American Transplant Congress 2013
- Place of Presentation
  Seattle USA
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] 肝臓内免疫応答制御による膵島グラフト機能傷害克服の試み2013
- Author(s)
  石山宏平、その他
- Organizer
  第40回日本膵・膵島移植研究会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] Mesenchymal Stem Cells Suppress Cytotoxic Activity of Natural Killer Cells in Islet Cell Transplantation2013
- Author(s)
  Y. Saeki, K. Ishiyama, F. Hirata, Y. Tanaka, H. Ohdan
- Organizer
  American Transplant Congress
- Place of Presentation
  シアトル、USA
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] TRAIL-TRAIL受容体を介した肝臓内NK細胞による移植膵島傷害の解明2012
- Author(s)
  石山　宏平
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] TRAIL-TRAIL 受容体を介した肝臓内 NK 細胞による移植膵島傷害の解明2012
- Author(s)
  石山宏平、その他
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] 肝臓内免疫応答による移植後膵島グラフト機能傷害克服の試み2012
- Author(s)
  石山宏平、その他
- Organizer
  第48回日本移植学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] 間葉系幹細胞を用いた肝臓内 NK 細胞活性化制御による移植膵島生着率改善の検討2012
- Author(s)
  田文宏、石山宏平、その他
- Organizer
  第39回日本臓器保存生物医学会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] Hotta R, Ishiyama K, Ohira M, Igarashi Y, Tanaka Y, Onoe T, Ide K, Tashiro H, Ohdan H. Adoptive Immunotherapy with Donor Derived-Liver Natural Killer Cells Prevents HCC Recurrence after Liver Transplantation in Recipients Exceeding the Milan Criteria.2012
- Author(s)
  Hotta R, Ishiyama K, Ohira M, Igarashi Y, Tanaka Y, Onoe T, Ide K, Tashiro H, Ohdan H
- Organizer
  American Transplantation Congress 2012
- Place of Presentation
  Boston, America
- Data Source
  KAKENHI-PROJECT-24591880
[Presentation] 肝臓内免疫応答による移植後膵島グラフト傷害機構の解明と克服2012
- Author(s)
  石山　宏平
- Organizer
  第48回日本移植学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] 肝臓は膵島移植に適した場所か?-肝臓内NK細胞による膵島移植後のグラフト傷害の解明-2011
- Author(s)
  石山宏平
- Organizer
  第47回日本移植学会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23890132
[Presentation] Comparative detection of natural antibodies to a-Gal and NeuGc epitopes in human sera2008
- Author(s)
  N., Basnet, H., Ohdan, H., Tahara, K., Ide, K., Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, K., Kajitani, M., Banshodani, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 11th meeting of Japanese Xenotransplantaion Society
- Place of Presentation
  Osaka
- Year and Date
  2008-02-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] Rejection and Cytotoxicity against xenogeneic antigen N-glycolylneuraminic acid (NeuGc)2008
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N., Basnet, K.,Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, K., Kajitani, M., Banshodani, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 11th meeting of Japanese Xenotransplantaion Society
- Place of Presentation
  Osaka
- Year and Date
  2008-02-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] Antibody-dependent rejection against xenogeneic antigen N-glycolylneuraminic acid (NeuGc)2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N., Basnet, K., Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, K., Kajitani, M., Banshodani, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 43th annual meeting of Japan Society for Transplantation
- Place of Presentation
  Sendai
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] Immunogenicity of xenogeneic antigen N-glycolylneuraminic acid (NeuGc)2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N., Basnet, K., Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 107th annual congress of Japan Surgical Society
- Place of Presentation
  Osaka
- Year and Date
  2007-04-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] Mechanism of avoidance of xenogeneic rejection by macrophages through intracellular inhibitory CD47-SHIPα signaling2007
- Author(s)
  K., Ide, H., Ohdan, H., Tahara, N., Basnet, K.,Ishiyama, Y., Tanaka, M., Shishida, T., Irei, M., Ohira, Y., Igarashi, T., Asahara
- Organizer
  The 10th meeting of Japanese Xenotransplantaion Society
- Place of Presentation
  Tokyo
- Year and Date
  2007-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] Immunogenicity of xenogeneic antigen N-glycolylneuraminic acid (NeuGc)2007
- Author(s)
  H., Tahara, H., Ohdan, K., Ide, N., Basnet, K., Ishiyama, M., Shishida, Y., Tanaka, T., Irei, M., Ohira, Y., Igarashi, M., Doskali, H., Takematsu, Y., Kozutsumi, T., Asahara
- Organizer
  The 10th meeting of Japanese Xenotransplantaion Society
- Place of Presentation
  Tokyo
- Year and Date
  2007-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] Avoidance of xenogeneic rejection by macrophages through intracellular inhibitory CD47-SIRPα signaling2006
- Author(s)
  K., Ide, H., Ohdan, H., Tahara, K., Ishiyama, Y., Tanaka, M., Shishida, T., Irei, M., Ohira, T., Asahara
- Organizer
  The 42th annual meeting of Japan Society for Transplantation
- Place of Presentation
  Chiba
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390348
[Presentation] 膵島移植後早期から長期にかけて肝臓内memory NK細胞がグラフトに与える免疫応答機構の解析
- Author(s)
  佐伯吉弘、石山宏平
- Organizer
  日本膵・膵島移植研究会
- Place of Presentation
  東京
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] 膵島保護へむけた膵島移植における肝臓内Natural Killer細胞活性化機構の解明
- Author(s)
  佐伯吉弘、石山宏平
- Organizer
  日本臓器保存生物医学会
- Place of Presentation
  大阪
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] Liver DX5- natural killer cells play a crucial role on the instant blood-mediated inflammatory reaction after islet transplantation
- Author(s)
  佐伯吉弘、石山宏平
- Organizer
  American Transplant Congress
- Place of Presentation
  サンフランシスコ、USA
- Year and Date
  2014-07-26 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] 肝移植後活性化NK 細胞移入療法がT 細胞抗ドナー応答に与える影響解析
- Author(s)
  田中友加,石山宏平, 大平真裕, 清水誠一, 井手健太郎, 尾上隆司, 小林剛, 田代裕尊, 大段秀樹.
- Organizer
  第32回日本肝移植研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-03 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24591880
[Presentation] 膵島移植後グラフト傷害に対する肝臓内Memory Natural killer細胞の機能解析
- Author(s)
  佐伯吉弘、石山宏平
- Organizer
  日本消化器外科学会
- Place of Presentation
  福島
- Year and Date
  2014-07-16 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] 膵島移植のInstant blood―mediated inflammatory reaction（IBMIR）環境下におけるNatural Killer（NK）細胞の活性化機構の解明
- Author(s)
  佐伯吉弘、石山宏平
- Organizer
  日本外科学会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-25461948
[Presentation] 膵島移植後におけるIBMIRを介した肝臓内NK細胞活性化メカニズムの解析
- Author(s)
  佐伯吉弘、石山宏平
- Organizer
  日本移植学会
- Place of Presentation
  東京
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25461948

1. IWASAKI KENTA (10508881)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
2. OHDAN Hideki (10363061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. Kobayashi Takaaki (70314010)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
4. 三輪祐子 (90572941)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
5. TANAKA Yuka (90432666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 野田貴幸 (50817088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 勝野敬之 (60642337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 恒川新 (40612768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ishiyama Kohei 石山 宏平

ISHIYAMA Kohei 石山 宏平

Research Projects

Research Products

Co-Researchers

ヒト乳歯歯髄幹細胞を用いた膵島オルガノイドによる画期的膵島移植プロトコールの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Indirect Alloreactive T-Cells and Application to Monitoring of anti-Donor Antibody Sensing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of control method of immune response after multiple islet transplantation in anticipation of ES/iPS cell transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

From treatment to prevention: development of innovative immune regulation based on epitope/paratope analysis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of intrahepatic immunization and development of intrahepatic immune control after islet transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The suppressive mechanism of liver immune reactivity after islet transplantation by mesenchymal stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of TRAIL positive NK cells from hematopoietic stem cells / iPS cells in vitro for anti-HCC immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cytotoxic activity of liver NK cells against islet graftPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of innate and adaptive immune responses in xenotransplantation by modulating CD47sirp α signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Estimation of Sensitization Status in Renal Transplant Recipients by Assessing Indirect Pathway CD4+ T Cell Response to Donor Cell-pulsed Dendritic Cell2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improved detection of donor-specific HLA-class II antibody in kidney transplant recipients by modified immunocomplex capture fluorescence analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cotransplantation of preactivated mesenchymal stem cells improves intraportal engraftment of islets by inhibiting liver natural killer cells in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Natural Killer Cells in the Innate Immune System After Intraportal Islet Transplantation in Mice.2017

Ishiyama Kohei 石山宏平

ISHIYAMA Kohei 石山宏平