Hirakawa Hitoshi 平川仁

Researcher Number	50437993
Other IDs
Affiliation (Current)	2025: 琉球大学, 病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 琉球大学, 病院, 講師 2019: 琉球大学, 医学部附属病院, 講師 2018: 琉球大学, 医学(系)研究科(研究院), 講師 2017: 琉球大学, 医学部附属病院, 講師 2016: 琉球大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator 頭頸部癌 / IP関連副鼻腔癌 / Exon20insertion / ｃｔDNA / 頭頸部腫瘍 / ctDNA / リキッドバイオプシー / 放射線療法 / 化学療法 / XRCC1 … More / ERCC1 / DNA修復酵素の遺伝子多型 / DNA修復酵素 / 遺伝子多型 / 化学放射線療法 / 手術 / DNA修復酵素遺伝子多型 … More Except Principal Investigator 頭頸部癌 / Torin / head and neck cancer / 耳鼻咽喉科 / less invasive treatment / human papilloma virus / mTOR経路 / 癌幹細胞 / 下咽頭癌 / アルコール代謝遺伝子 / 頭頸部癌予防 / 生活習慣 / 遺伝子多型 / たばこ代謝関連遺伝子 / アルコール代謝関連遺伝子 / 新規低侵襲治療 / PLD阻害 / ラパログ / PI3K/Akt/mTOR経路阻害 / PI3K/Akt/mTOR / 増殖抑制 / 薬剤感受性 / テムシロリムス / エベロリムス / ヒト乳頭腫ウイルス / ｍTOR阻害薬 / PLD inhibitor / mTOR inhibitor / イメージング質量分析 / 微小癌 / 可視化 / イメージング / GGT1 / ガンマーグルタミルトランスフェラーゼ1 / プロテオグリーン / 術中イメージング Less

頭頸部癌の癌幹細胞を標的にした新規薬物治療の開発
- Principal Investigator
  
  近藤俊輔
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
Development of novel minimally invasive therapy in head and neck cancer
- Principal Investigator
  
  鈴木幹男
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
リキッドバイオプシーを用いたエクソソームマイクロRNAの網羅的解析
- Principal Investigator
  
  比嘉朋代
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
The role of EGFR Exon 20 insertion in IP related sinonasal cancerPrincipal Investigator
- Principal Investigator
  
  平川仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
Development of minimally invasive treatment in head and neck cancer focused on PI3K/Akt/mTOR pathway
- Principal Investigator
  
  Suzuki Mikio
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
Genetic polymorphisms and lifestyle related to head and neck cancer development
- Principal Investigator
  
  Higa Tomoyo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
Establishment and clinical application of ctDNA detection in head and neck cancerPrincipal Investigator
- Principal Investigator
  
  Hirakawa Hitoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of the Ryukyus
DNA-repair gene polymorphisms predict clinical outcome among patients with head and neck cancerPrincipal Investigator
- Principal Investigator
  
  Hirakawa Hitoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of the Ryukyus
Do not miss head and neck small cancer: establishment of micro cancer identification method with a novel fluorescent probe
- Principal Investigator
  
  Ikegami Taro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of the Ryukyus

All 2023 2022 2021 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] 特集高齢者の疑問にどう答えるか口腔･咽頭･食道領域のどに乳頭腫があるといわれましたが,何が原因ですか?2023
- Author(s)
  鈴木幹男、金城秀俊、平川仁
- Journal Title
  
  JOHNS
  
  Volume: 39 Issue: 9 Pages: 1073-1076
- DOI
  10.24479/ohns.0000000747
- ISSN
  0910-6820
- Year and Date
  2023-09-01
- Data Source
  KAKENHI-PROJECT-21K09585
[Journal Article] p16 Overexpression in Sinonasal Squamous Cell Carcinoma: Association with Human Papillomavirus and Prediction of Survival Outcomes2023
- Author(s)
  Hirakawa Hitoshi、Ikegami Taro、Touyama Masatomo、Ooshiro Yurika、Higa Tomoyo、Higa Teruyuki、Agena Shinya、Kinjyo Hidetoshi、Kondo Shunsuke、Kise Norimoto、Tanaka Katsunori、Maeda Hiroyuki、Tamaki Tomoko、Wada Naoki、Suzuki Mikio
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 21 Pages: 6861-6861
- DOI
  10.3390/jcm12216861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09585, KAKENHI-PROJECT-21K09635
[Journal Article] Human Papillomavirus Infection and EGFR Exon 20 Insertions in Sinonasal Inverted Papilloma and Squamous Cell Carcinoma2023
- Author(s)
  Hirakawa Hitoshi、Ikegami Taro、Kise Norimoto、Kinjyo Hidetoshi、Kondo Shunsuke、Agena Shinya、Hasegawa Narumi、Kawakami Junko、Maeda Hiroyuki、Suzuki Mikio
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 13 Issue: 4 Pages: 657-657
- DOI
  10.3390/jpm13040657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09635, KAKENHI-PROJECT-20K09758, KAKENHI-PROJECT-21K09585
[Journal Article] Biomarkers for Predicting Anti-Programmed Cell Death-1 Antibody Treatment Effects in Head and Neck Cancer2023
- Author(s)
  Tanaka Katsunori、Hirakawa Hitoshi、Suzuki Mikio、Higa Teruyuki、Agena Shinya、Hasegawa Narumi、Kawakami Junko、Toyama Masatomo、Higa Tomoyo、Kinjyo Hidetoshi、Kise Norimoto、Kondo Shunsuke、Maeda Hiroyuki、Ikegami Taro
- Journal Title
  
  Current Oncology
  
  Volume: 30 Issue: 6 Pages: 5409-5424
- DOI
  10.3390/curroncol30060410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09585, KAKENHI-PROJECT-21K09635
[Journal Article] Distribution pattern and pathologic analysis of metastatic sentinel and non-sentinel lymph nodes in lymphatic basin dissection for clinical T2/T3 oral cancer with clinical N0 status2022
- Author(s)
  Hirakawa Hitoshi、Matsuzuka Takashi、Uemura Hirokazu、Yoshimoto Seiichi、Miura Kouki、Shiotani Akihiro、Sugasawa Masashi、Homma Akihiro、Yokoyama Junkichi、Tsukahara Kiyoaki、Yoshizaki Tomokazu、Hanai Nobuhiro、Suzuki Hidenori、Suzuki Mikio、Hasegawa Yasuhisa
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 49 Issue: 4 Pages: 680-689
- DOI
  10.1016/j.anl.2021.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09758, KAKENHI-PROJECT-21K09620, KAKENHI-PROJECT-21K19557
[Journal Article] 特集ウイルス感染症に強くなる!-予防・診断・治療のポイント《各論》ヒト乳頭腫ウイルスと関連腫瘍2022
- Author(s)
  鈴木幹男、平川仁
- Journal Title
  
  耳鼻咽喉科・頭頸部外科
  
  Volume: 94 Pages: 655-659
- Data Source
  KAKENHI-PROJECT-21K09585
[Journal Article] Therapeutic efficacy of selective intraarterial chemoradiotherapy with docetaxel and nedaplatin for human papilloma virus-negative oropharyngeal cancer2022
- Author(s)
  Heianna Joichi、Makino Wataru、Hirakawa Hitoshi、Agena Shinya、Tomita Hayato、Ariga Takuro、Ishikawa Kazuki、Takehara Shota、Kusada Takeaki、Maemoto Hitoshi、Maeda Hiroyuki、Murayama Sadayuki
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 49 Issue: 3 Pages: 468-476
- DOI
  10.1016/j.anl.2021.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09758, KAKENHI-PROJECT-21K15814
[Journal Article] Effects of Nivolumab for the Head and Neck Carcinoma Patients2022
- Author(s)
  Tanaka Katsunori、Maeda Hiroyuki、Kinjo Hidetoshi、Agena Shinya、Hirakawa Hitoshi、Suzuki Mikio
- Journal Title
  
  Practica Oto-Rhino-Laryngologica
  
  Volume: 115 Pages: 875-881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09585
[Journal Article] Correction to: Effectiveness and safety of nivolumab in patients with head and neck cancer in Japanese real?world clinical practice: a multicentre retrospective clinical study2021
- Author(s)
  Hanai Nobuhiro、Shimizu Yasushi、Kariya Shin、Hirakawa Hitoshi、Yamauchi Moriyasu、Watanabe Akihito、Omori Koichi、Yamazaki Tomoko、Monden Nobuya、Kudo Naomi、Arai Makoto、Sakurai Daiju、Asakage Takahiro、Doi Issei、Yamada Takayuki、Homma Akihiro
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 5 Pages: 1005-1006
- DOI
  10.1007/s10147-021-01879-y
- Data Source
  KAKENHI-PROJECT-20K09758
[Journal Article] Patterns of recurrence after low-dose postoperative radiotherapy for head and neck squamous cell carcinoma2021
- Author(s)
  Makino Wataru、Heianna Joichi、Ishikawa Kazuki、Kusada Takeaki、Maemoto Hitoshi、Ariga Takuro、Matayoshi Akira、Nakasone Toshiyuki、Hirakawa Hitoshi、Agena Shinya、Yamashita Yukashi、Maeda Hiroyuki、Murayama Sadayuki
- Journal Title
  
  Journal of the Egyptian National Cancer Institute
  
  Volume: 33 Issue: 1 Pages: 40-40
- DOI
  10.1186/s43046-021-00098-w
- Data Source
  KAKENHI-PROJECT-20K09758
[Journal Article] Outcomes of long-term nivolumab and subsequent chemotherapy in Japanese patients with head and neck cancer: 2-year follow-up from a multicenter real-world study2021
- Author(s)
  Yasumatsu Ryuji、Shimizu Yasushi、Hanai Nobuhiro、Kariya Shin、Yokota Tomoya、Fujii Takashi、Tsukahara Kiyoaki、Ando Mizuo、Hanyu Kenji、Ueda Tsutomu、Hirakawa Hitoshi、Takahashi Shunji、Ono Takeharu、Sano Daisuke、et al.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 27 Issue: 1 Pages: 95-104
- DOI
  10.1007/s10147-021-02047-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09895, KAKENHI-PROJECT-20K09758
[Journal Article] Effectiveness of nivolumab affected by prior cetuximab use and neck dissection in Japanese patients with recurrent or metastatic head and neck cancer: results from a retrospective observational study in a real-world setting2021
- Author(s)
  Kariya Shin、Shimizu Yasushi、Hanai Nobuhiro、Yasumatsu Ryuji、Yokota Tomoya、Fujii Takashi、Tsukahara Kiyoaki、Yoshida Masafumi、Hanyu Kenji、Ueda Tsutomu、Hirakawa Hitoshi、Takahashi Shunji、Ono Takeharu、Sano Daisuke、et al.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 6 Pages: 1049-1056
- DOI
  10.1007/s10147-021-01900-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09895, KAKENHI-PROJECT-20K09758
[Journal Article] Development of Antibodies against HPV-6 and HPV-11 for the Study of Laryngeal Papilloma2021
- Author(s)
  Ikegami Taro、Kise Norimoto、Kinjyo Hidetoshi、Kondo Shunsuke、Suzuki Mikio、Tsukahara Narutoshi、Murakami Akikazu、Kiyuna Asanori、Agena Shinya、Tanaka Katsunori、Hasegawa Narumi、Kawakami Junko、Ganaha Akira、Maeda Hiroyuki、Hirakawa Hitoshi
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 10 Pages: 2024-2024
- DOI
  10.3390/v13102024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09758, KAKENHI-PROJECT-21K09635
[Journal Article] Prognostic importance of pathological response to neoadjuvant chemotherapy followed by definitive surgery in advanced oral squamous cell carcinoma.2017
- Author(s)
  Hirakawa H, Hanai N, Suzuki H, Nishikawa D, Matayoshi S, Hasegawa Y
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 47 Issue: 11 Pages: 1038-1046
- DOI
  10.1093/jjco/hyx097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11247, KAKENHI-PROJECT-17K11391, KAKENHI-PROJECT-16K15722
[Journal Article] Detection of human papillomavirus in branchial cleft cysts2017
- Author(s)
  Ikegami T, Uehara T, Deng Z, Kondo S, Maeda H, Kiyuna A, Agena S, Hirakawa H, Yamashita Y, Ganaha A, Suzuki M
- Journal Title
  
  Oncology Letters
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15722
[Presentation] 舌癌に対するセンチネルリンパ節生検の有用性2021
- Author(s)
  平川仁
- Organizer
  SNNS研究会学術集会
- Data Source
  KAKENHI-PROJECT-20K09758
[Presentation] 鼻副鼻腔内反性乳頭腫の基礎と臨床2021
- Author(s)
  平川仁
- Organizer
  日本鼻科学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09758
[Presentation] 下咽頭癌導入化学療法におけるDNA修復酵素遺伝子多型を用いた効果予測2021
- Author(s)
  平川仁
- Organizer
  第59回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09758
[Presentation] DNA修復酵素遺伝子多型解析による頭頸部癌治療の効果予測2019
- Author(s)
  平川仁
- Organizer
  第120回日本耳鼻咽喉科学会・学術総会
- Data Source
  KAKENHI-PROJECT-17K11391
[Presentation] 当科におけるオプジーボの初期使用経験2018
- Author(s)
  平川仁、山下懐、上原貴行、安慶名信也、上里迅、真栄田裕行、鈴木幹男
- Organizer
  第28回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-16K15722
[Presentation] DNA修復酵素遺伝子多型解析による頭頸部癌治療の効果予測2017
- Author(s)
  平川仁
- Organizer
  日本耳鼻咽喉科学会総会
- Data Source
  KAKENHI-PROJECT-17K11391
[Presentation] DNA修復酵素遺伝子多型解析による頭頸部癌治療の効果予測2017
- Author(s)
  平川仁、山下懐、上原貴行、比嘉朋代、平塚宗久、照喜名玲奈、鈴木幹男
- Organizer
  第118回日本耳鼻咽喉科総会
- Data Source
  KAKENHI-PROJECT-16K15722
[Presentation] 舌癌に対するセンチネルリンパ節生検の有用性ー舌リンパ節の検出例を通してー2016
- Author(s)
  平川仁、山下懐、上原貴行、平塚宗久、喜瀬乗基、照喜名怜奈、池上太郎、鈴木幹男
- Organizer
  第31回九州連合地方部会
- Place of Presentation
  嬉野温泉和多屋別荘（佐賀県嬉野市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-16K15722

1. Ikegami Taro (00754409)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
2. 山下懐 (60569622)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. Suzuki Mikio (00226557)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. Higa Tomoyo (40794904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 真栄田裕行 (40264501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 又吉宣 (60448587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 近藤俊輔 (90596363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 安慶名信也 (30593496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HASEGAWA Yasuhisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 鈴木雅明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 佐野大佑

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirakawa Hitoshi 平川 仁

Research Projects

Research Products

Co-Researchers

頭頸部癌の癌幹細胞を標的にした新規薬物治療の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel minimally invasive therapy in head and neck cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リキッドバイオプシーを用いたエクソソームマイクロRNAの網羅的解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of EGFR Exon 20 insertion in IP related sinonasal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of minimally invasive treatment in head and neck cancer focused on PI3K/Akt/mTOR pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic polymorphisms and lifestyle related to head and neck cancer development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment and clinical application of ctDNA detection in head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DNA-repair gene polymorphisms predict clinical outcome among patients with head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Do not miss head and neck small cancer: establishment of micro cancer identification method with a novel fluorescent probe

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 特集 高齢者の疑問にどう答えるか 口腔･咽頭･食道領域 のどに乳頭腫があるといわれましたが,何が原因ですか?2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] p16 Overexpression in Sinonasal Squamous Cell Carcinoma: Association with Human Papillomavirus and Prediction of Survival Outcomes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Papillomavirus Infection and EGFR Exon 20 Insertions in Sinonasal Inverted Papilloma and Squamous Cell Carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biomarkers for Predicting Anti-Programmed Cell Death-1 Antibody Treatment Effects in Head and Neck Cancer2023

Author(s)

Journal Title

DOI

Data Source

Hirakawa Hitoshi 平川仁

[Journal Article] 特集高齢者の疑問にどう答えるか口腔･咽頭･食道領域のどに乳頭腫があるといわれましたが,何が原因ですか?2023

[Journal Article] 特集ウイルス感染症に強くなる!-予防・診断・治療のポイント《各論》ヒト乳頭腫ウイルスと関連腫瘍2022

[Presentation] 下咽頭癌導入化学療法におけるDNA修復酵素遺伝子多型を用いた効果予測2021