Kaneko Haruka 金子晴香

… Alternative Names

KANEKO Haruka 金子晴香

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Researcher Number	50445516
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 順天堂大学, 医学部, 准教授 2018 – 2020: 順天堂大学, 医学部, 講師 2013 – 2017: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 骨棘 / 変形性膝関節症 / パールカン / 滑膜 / 滑膜炎 / TGF-β / 軟骨分化 / IL‐6 / TGF-beta / IL-6 … More / 変形性膝関節症モデル / 多能性前駆細胞 / 半月板逸脱 / マクロファージ / 炎症性メディエーター / 炎症性メディエイター / Smad2 / 軟骨下骨 / プロテオグリカン … More Except Principal Investigator 変形性膝関節症 / 骨棘 / 軟骨摩耗 / 半月板逸脱 / 軟骨下骨病変 / 画像診断 / 組織内微小環境 / 関節軟骨破壊再生 / 骨軟骨棘 / 画像解析 / 関節軟骨破壊 / HYBID / ヒアルロン酸 / 変形性関節症 Less

Pathophysiology and mechanism of the progression of subchondral bone lesions in knee osteoarthritis
- Principal Investigator
  
  石島旨章
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Mechanism analysis and disease inhibition of synovitis and osteophyte formation in knee osteoarthritisPrincipal Investigator
- Principal Investigator
  
  金子晴香
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Pathophysiological study and image analysis of early-stage knee OA by focusing on osteochondrophytes
- Principal Investigator
  
  Okada Yasunori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Regulation and mechanisms elucidation of synovitis in knee osteoarthritisPrincipal Investigator
- Principal Investigator
  
  Kaneko Haruka
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Regulation of osteophyte formation in knee osteoarthritis by modulating the function of perlecan expressed in synoviumPrincipal Investigator
- Principal Investigator
  
  Kaneko Haruka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University
The functional analysis of perlecan in the late stage of osteophyte formation in knee osteoarthritisPrincipal Investigator
- Principal Investigator
  
  KANEKO Haruka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 Other

All Journal Article Presentation

[Journal Article] IL-6 Reduces Spheroid Sizes of Osteophytic Cells Derived from Osteoarthritis Knee Joint via Induction of Apoptosis2024
- Author(s)
  Negishi Yoshifumi、Adili Arepati、de Vega Susana、Momoeda Masahiro、Kaneko Haruka、Cilek Mehmet Z.、Yoshinaga Chiho、Takafuji Kazuaki、Otsuka Yuta、Shimoda Masayuki、Negishi-Koga Takako、Ishijima Muneaki、Okada Yasunori
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 194 Issue: 1 Pages: 135-149
- DOI
  10.1016/j.ajpath.2023.10.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09259, KAKENHI-PROJECT-22K07029, KAKENHI-PROJECT-18K09082
[Journal Article] Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study2023
- Author(s)
  Negishi Y、Kaneko H、Aoki T、Liu L、Adili A、Arita H、Hada S、Momoeda M、Huang H、Tomura J、Wakana S、Shiozawa J、Kubota M、Someya Y、Tamura Y、Aoki S、Watada H、Kawamori R、Negishi-Koga T、Okada Y、Ishijima M
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 22805-22805
- DOI
  10.1038/s41598-023-49868-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15750, KAKENHI-PROJECT-21K09259, KAKENHI-PROJECT-22K07029, KAKENHI-PROJECT-18K09082
[Journal Article] Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis ? The Bunkyo Health Study2023
- Author(s)
  Adili Arepati、Kaneko Haruka、Aoki Takako、Liu Lizu、Negishi Yoshifumi、Tomura Jun、Wakana Suguru、Momoeda Masahiro、Arita Hitoshi、Hada Shinnosuke、Shiozawa Jun、Kubota Mitsuaki、Someya Yuki、Tamura Yoshifumi、Aoki Shigeki、Watada Hirotaka、Kawamori Ryuzo、Negishi-Koga Takako、Okada Yasunori、Ishijima Muneaki
- Journal Title
  
  Osteoarthritis and Cartilage Open
  
  Volume: 5 Issue: 3 Pages: 100364-100364
- DOI
  10.1016/j.ocarto.2023.100364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15750, KAKENHI-PROJECT-21K09259, KAKENHI-PROJECT-22K07029, KAKENHI-PROJECT-18K09082
[Journal Article] Synergistic upregulation of ADAMTS4 (aggrecanase-1) by cytokines and its suppression in knee osteoarthritic synovial fibroblasts2021
- Author(s)
  Cilek Mehmet Zeynel、de Vega Susana、Shiozawa Jun、Yoshinaga Chiho、Miyamae Yuka、Chijiiwa Miyuki、Mochizuki Satsuki、Ito Masatoshi、Kaneko Haruka、Kaneko Kazuo、Ishijima Muneaki、Okada Yasunori
- Journal Title
  
  Laboratory Investigation
  
  Volume: 102 Issue: 1 Pages: 102-111
- DOI
  10.1038/s41374-021-00685-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-21K06958, KAKENHI-PROJECT-20K18075, KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-22K07029
[Journal Article] Medial meniscus extrusion is a determinant factor for the gait speed among MRI-detected structural alterations of knee osteoarthritis2021
- Author(s)
  Arita Hitoshi、Kaneko Haruka、Ishibashi Masayoshi、Sadatsuki Ryo、Liu Lizu、Hada Shinnosuke、Kinoshita Mayuko、Aoki Takako、Negishi Yoshifumi、Momoeda Masahiro、Adili Arepati、Kubota Mitsuaki、Okada Yasunori、Kaneko Kazuo、Ishijima Muneaki
- Journal Title
  
  Osteoarthritis and Cartilage Open
  
  Volume: 3 Issue: 3 Pages: 100176-100176
- DOI
  10.1016/j.ocarto.2021.100176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-18K09082
[Journal Article] Deletion of Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization (HYBID) Results in Attenuation of Osteoarthritis in Mice2021
- Author(s)
  Momoeda Masahiro、de Vega Susana、Kaneko Haruka、Yoshinaga Chiho、Shimoda Masayuki、Nakamura Tomomi、Endo Yoko、Yoshida Hiroyuki、Kaneko Kazuo、Ishijima Muneaki、Okada Yasunori
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 191 Issue: 11 Pages: 1986-1998
- DOI
  10.1016/j.ajpath.2021.07.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07422, KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-18K09082
[Journal Article] Implication of HYBID (Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization) in Hyaluronan Degradation by Synovial Fibroblasts in Patients with Knee Osteoarthritis.2020
- Author(s)
  Shiozawa J, de Vega S, Cilek MZ, Yoshinaga C, Nakamura T, Kasamatsu S, Yoshida H, Kaneko H, Ishijima M, Kaneko K, Okada Y.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 190 Issue: 5 Pages: 1046-1058
- DOI
  10.1016/j.ajpath.2020.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09083, KAKENHI-PROJECT-17K08770, KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-20K18075, KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-20K07429
[Journal Article] 変形性膝関節症におけるHYBID（CEMIP/KIAA1199）の発現と役割―早期変形性膝関節症のバイオマーカーとしての可能性も含めてー2019
- Author(s)
  塩澤淳, 石島旨章, 金子和夫, 岡田保典
- Journal Title
  
  整形・災害外科
  
  Volume: 62 Pages: 1519-1525
- Data Source
  KAKENHI-PROJECT-19H03788
[Journal Article] 変形性膝関節症における慢性疼痛2019
- Author(s)
  石島旨章、金子晴香、根岸義文、百枝雅裕、岡田保典、金子和夫
- Journal Title
  
  日本臨床
  
  Volume: 77 Pages: 2027-2034
- Data Source
  KAKENHI-PROJECT-19H03788
[Journal Article] The medial proximal tibial angle accurately corrects the limb alignment in open-wedge high tibial osteotomy2018
- Author(s)
  Kubota Mitsuaki、Ohno Ryuichi、Sato Taisuke、Yamaguchi Junichiro、Kaneko Haruka、Kaneko Kazuo、Ishijima Muneaki
- Journal Title
  
  Knee Surgery, Sports Traumatology, Arthroscopy
  
  Volume: ‐ Issue: 8 Pages: 2410-2416
- DOI
  10.1007/s00167-018-5216-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09083, KAKENHI-PROJECT-18K09082
[Journal Article] The increase in bone mineral density by bisphosphonate with active vitamin D analog is associated with the serum calcium level within the reference interval in postmenopausal osteoporosis2018
- Author(s)
  Kinoshita Mayuko、Ishijima Muneaki、Kaneko Haruka、Liu Lizu、Nagao Masashi、Sadatsuki Ryo、Hada Shinnosuke、Arita Hitoshi、Aoki Takako、Yamanaka Makoto、Nojiri Hidetoshi、Sakamoto Yuko、Tokita Akifumi、Kaneko Kazuo
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 1 Pages: 1-8
- DOI
  10.1080/14397595.2018.1442671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20068, KAKENHI-PROJECT-18K09083
[Journal Article] Mid and long term outcomes after fixation of osteochondritis dissecans2018
- Author(s)
  Kubota Mitsuaki、Ishijima Muneaki、Ikeda Hiroshi、Takazawa Yuji、Saita Yoshitomo、Kaneko Haruka、Kurosawa Hisashi、Kaneko Kazuo
- Journal Title
  
  Journal of Orthopaedics
  
  Volume: 15 Issue: 2 Pages: 536-539
- DOI
  10.1016/j.jor.2018.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-18K09083
[Journal Article] Bone marrow lesion is associated with disability for activities of daily living in patients with early stage knee osteoarthritis2018
- Author(s)
  Sadatsuki Ryo、Ishijima Muneaki、Kaneko Haruka、Liu Lizu、Futami Ippei、Hada Shinnosuke、Kinoshita Mayuko、Kubota Mitsuaki、Aoki Takako、Takazawa Yuji、Ikeda Hiroshi、Okada Yasunori、Kaneko Kazuo
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 37 Issue: 3 Pages: 529-536
- DOI
  10.1007/s00774-018-0950-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-18K09083, KAKENHI-PROJECT-16H05454
[Journal Article] Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in the patients with eraly-stage knee osteoarthritis.2017
- Author(s)
  Hada S., Ishijima M., Kaneko H., Kinoshita M., Liu L., Sadatusuki R., Futami I., Yusup A., Takamura T., Arita H., Shiozawa J., Aoki T., Takazawa Y., Ikeda H., Aoki S., Kurosawa H., Okada Y. and Kaneko K.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 19 Issue: 1 Pages: 201-201
- DOI
  10.1186/s13075-017-1411-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05454, KAKENHI-PROJECT-15K10494, KAKENHI-PROJECT-15K20019, KAKENHI-PROJECT-16K20069
[Journal Article] Serum interleukin 6 levels are associated with depressive state of the patients with knee osteoarthritis irrespective of disease severity2017
- Author(s)
  Shimura Y, Kurosawa H, Tsuchiya M, Sawa M, Kaneko H, Liu L, Makino Y, Nojiri H, Iwase Y, Kaneko K, Ishijima M
- Journal Title
  
  Clin Rheumatol
  
  Volume: 36 Issue: 12 Pages: 2781-2787
- DOI
  10.1007/s10067-017-3826-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10494, KAKENHI-PROJECT-15K20019
[Journal Article] Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression2017
- Author(s)
  Sadatsuki R, Kaneko H, Futami I, Kinoshita M, Nonaka R, Culley KL, Otero M, Hada S, Goldring MB, Yamada Y, Kaneko K, Arikawa-Hirasawa E, Ishijima M
- Journal Title
  
  J Orthop Res
  
  Volume: 35 Issue: 4 Pages: 837-46
- DOI
  10.1002/jor.23318
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10494, KAKENHI-PROJECT-15K20019, KAKENHI-PROJECT-15K09326
[Presentation] Medial meniscus tear progresses medial meniscus extrusion beyond osteophyte width in middled-aged populations with K/L 0 -Data from the Osteoarthritis Initiative2023
- Author(s)
  Kaneko H
- Organizer
  2023 OARSI World Congress on Osteoarthritis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09259
[Presentation] 早期変形性膝関節症への治療の深化～TKA前にできる治療～　早期変形性膝関節症の病態から考える治療法　半月板と骨棘(シンポジウム)2023
- Author(s)
  金子晴香, 石島旨章
- Organizer
  第51回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09259
[Presentation] Osteophyte formation progresses when synovitis was stronger in middle-aged populations with grade 0 of Kellegren-Lawrece classification -The Osteoarthritis Initiative.2022
- Author(s)
  H Kaneko, A Arepati, T Aoki, L Liu, Y Negishi, J Tomura, S Wakana, K Yoshida, K Kobayashi, M Momoeda, H Arita, M Kubota, M Ishijima.
- Organizer
  OARSI World Congress 2022, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-21K09259
[Presentation] パールカン遺伝子変異による軟骨異常を解析する細胞モデルの構築2022
- Author(s)
  白崎駿, 中田智史, 山下由莉, 金子晴香, 石島旨章, 櫻井英俊, 平澤恵理
- Organizer
  第37回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] Hybid（hyaluronan-binding protein involved in hyaluronan depolymerization）によるHA分解はマウスでの変形性膝関節症（膝OA）を促進する2021
- Author(s)
  百枝雅裕、スサーナ・デ・ベガ、金子晴香、良永知穂、下田将之、中村朋美、遠藤洋子、吉田浩之、金子和夫、石島旨章、岡田保典
- Organizer
  第53回日本結合組織学会
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] 早期変形性膝関節症の滑膜病変におけるパールカンの機能2021
- Author(s)
  有田均, 金子晴香, 羽田晋之介, 木下真由子, 定月亮, 二見一平, 根岸義文, 百枝雅裕, 平澤恵理, 石島旨章
- Organizer
  第53回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] 新規ヒアルロニダーゼHYBID及びTMEM2の膝OA関節軟骨組織における機能解析2021
- Author(s)
  塩澤淳、Susana de Vega、良永知穂、中村智美、吉田浩之、金子晴香、金子和夫、石島旨章、岡田保典
- Organizer
  第13回日本関節鏡・膝・スポーツ整形外科学会（JOSKAS）
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] 変形性膝関節症滑膜組織でのHYBID過剰発現は関節液中ヒアルロン酸（HA）分解に関わる。2020
- Author(s)
  塩澤淳、Susana de Vega、Mehmet Z. Cilek、良永知穂、中村智美、笠松慎也、吉田浩之、石島旨章、金子晴香、金子和夫、岡田保典
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] 変形性膝関節症（膝OA）の関節軟骨組織におけるヒアルロン酸分解酵素（HYBIDとTMEM2）の発現と発現調節機構2020
- Author(s)
  塩澤淳、Susana de Vega、中村智美、吉田浩之、石島旨章、金子晴香、金子和夫、岡田保典
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] HYBIDの変形性関節症（OA）関節軟骨での発現亢進とヒアルロン酸（HA）分解における役割2019
- Author(s)
  下田将之、清水英德、望月早月、吉田浩之、塩澤淳、石島旨章、金子和夫、中村雅也、戸山芳昭、岡田保典
- Organizer
  第108回日本病理学総会
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] 変形性膝関節症新規バイオマーカー・コラーゲン由来糖鎖修飾ヒドロキシリジンの有効性評価　診断能の検討.2019
- Author(s)
  金子晴香,石島旨章,田中智美,多賀祐喜,平澤恵理[有川],田中啓友,水野一乘,楠畑雅,服部俊治,金子和夫.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] HYBIDは変形性膝関節症滑膜組織で過剰発現し関節液中ヒアルロン酸分解に関与する2019
- Author(s)
  塩澤淳、Susan de Vega、Mehmet Z. Cilek、良永知穂、中村智美、笠松慎也、吉田浩之、金子晴香、石島旨章、金子和夫、岡田保典
- Organizer
  第51回日本結合組織学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] 早期変形性膝関節症の骨棘形成における滑膜に発現するperlecanの機能解析.2019
- Author(s)
  有田均,金子晴香,木下真由子,羽田晋之介,定月亮,根岸義文,百枝雅裕,;劉立足,平澤恵理[有川],金子和夫,石島旨章.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] IL-6を介した変形性関節症滑膜線維芽細胞によるHYBID（KIAA1199）過剰発現は関節液中ヒアルロン酸分解に関わる2019
- Author(s)
  塩澤淳、Susana de Vega、Mehmet Z. Cilek、良永知穂、中村智美、笠松慎也、吉田浩之、金子晴香、石島旨章、金子和夫、岡田保典
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03788
[Presentation] 末期変形性膝関節症のビタミンD充足状態と脛骨近位関節面傾斜角の関連.2019
- Author(s)
  金子晴香,石島旨章,有田均劉立足,根岸義文,百枝雅裕,齋田良知,高澤祐治,池田浩,金子和夫.
- Organizer
  第11回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] Role of synovial perlecan in osteophyte formation in early stage knee osteoarthritis.2019
- Author(s)
  Arita H, Kaneko H, Kinoshita M, Hada S, Sadatsuki R, Futami I, Negishi Y, Momoeda M, Liu L, Aoki T, Arikawa-Hirasawa E, Kaneko K, Ishijima M.
- Organizer
  OARSI2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] Pain reduction after high tibial osteotomy was associated with reduction of histological synovitis in patients with knee osteoarthritis; a longitudinal study.2018
- Author(s)
  Kaneko H, Liu L, Arita H, Aoki H, Negishi Y, Momoeda M, Hada S, Okada Y, Kaneko K, Ishijima M.
- Organizer
  OARSI 2018 World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] 初期変形性膝関節症の骨棘幅には性差がある　スポートロジーコアスタディ.2018
- Author(s)
  金子晴香,石島旨章,青木孝子,劉立足,羽田晋之介,有田均,根岸義文,百枝雅裕,田村好史,岡田保典,金子和夫.
- Organizer
  第91回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] 変形性膝関節症に対する高位脛骨骨切り術による疼痛改善と滑膜炎改善との関連を検討した縦断研究.2018
- Author(s)
  金子晴香,石島旨章,有田均,羽田晋之介,長尾雅史,齋田良知,高澤祐治,池田浩,金子和夫.
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K09083
[Presentation] パールカンにより制御される滑膜間葉系細胞の遺伝子の網羅的解析2017
- Author(s)
  有田均, 金子晴香, 石島旨章, 羽田晋之介, 木下真由子, 定月亮, 二見一平, 塩澤淳, 平澤恵理, 山田吉彦, 金子和夫
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-15K20019
[Presentation] パールカンが関連する膝滑膜間葉系細胞の遺伝子発現プロファイルの網羅的解析2017
- Author(s)
  有田均, 金子晴香, 石島旨章, 羽田晋之介, 木下真由子, 定月亮, 二見一平, 塩澤淳, 平澤恵理, 金子和夫
- Organizer
  第49回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-15K20019
[Presentation] Vitamin D status and index representing the detrimental mechanical loading across the knee joint in end-stage knee osteoarthritis representing the detrimental mechanical loading across the knee joint in end-stage knee osteoarthritis.2017
- Author(s)
  Mayuko Kinoshita, Haruka Kaneko, Muneaki Ishijima, Liu Liz, Ryo Sadatsuki, Shinnosuke Hada, Anwarjan Yusup, Hitoshi Arita, Jun Shiozawa, Takako Aoki, Yoshifumi Tamura, Ryuzo Kawamori, Kazuo Kaneko
- Organizer
  OARSI World Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20019
[Presentation] Perlecan regulates chondrogenic differentiation from synovial mesenchymal cells via Smad and MAPK signaling pathways2016
- Author(s)
  Mayuko K, Kaneko H, Sadatsuki R, Futami I, Hada S, Arita H, Shiozawa J, Hirasawa-Arikawa E, Yamada Y, Kaneko K, Ishijima M
- Organizer
  OARSI 2016 World Congress
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2016-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20019
[Presentation] パールカンによる滑膜間葉系細胞からの軟骨分化制御2016
- Author(s)
  木下真由子, 金子晴香, 石島旨章, 定月亮, 二見一平, 羽田晋之介, 有田均, 塩澤淳, 平澤恵理, Goldring Mary, 山田吉彦, 金子和夫
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡県
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K20019
[Presentation] パールカンによる滑膜間葉系細胞からの軟骨分化制御2016
- Author(s)
  木下真由子, 石島旨章, 金子晴香定月亮, 二見一平, 平澤恵理, Yamada Yoshihiko, 金子和夫
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎県
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K20019
[Presentation] Role of perlecan in chondrogenic, osteogenic and adipogenic differentiation of synovial mesenchymal cells2014
- Author(s)
  R. Sadatsuki, H. Kaneko, I. Futami, M. B. Goldring, Y. Yamada, E. Hirasawa, S. Hada, K. L. Culley, M. Otero, C. Dragomir, M. Kinoshita, L. Liu, A. Yusp, K. Kaneko, M. Ishijima
- Organizer
  2014 World Congress on Osteoarthritis
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-25861343
[Presentation] Perlecan is required for chondrogenic differentiation of mesenchymal synovial cells2013
- Author(s)
  H. Kaneko, R. Sadatsuki, K. L. Culley, M. Otero, I. Futami, S. Hada, E. Hirasawa-Arikawa, Y. Yamada, K. Kaneko, M. B. Goldring, M. Ishijima
- Organizer
  2013 World Congress on Osteoarthritis
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-25861343
[Presentation] パールカンによる滑膜間葉系細胞の維持ならびに分化誘導の制御
- Author(s)
  定月亮, 石島旨章, 金子晴香, 二見一平, 劉立足, Yusup Anwarjan, 羽田晋之介, 木下真由子, Goldring Mary B., Yamada Yoshihiko, 平澤恵理, 金子和夫
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル，鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-25861343
[Presentation] パールカンはSOX9遺伝子発現制御を介して滑膜間葉系細胞の軟骨分化誘導を制御する
- Author(s)
  定月亮，石島旨章，金子晴香，羽田晋之介，木下真由子，金子和夫，平澤恵理
- Organizer
  第47回日本結合組織学会学術大会
- Place of Presentation
  コクヨホール，東京
- Year and Date
  2015-05-15 – 2015-05-16
- Data Source
  KAKENHI-PROJECT-25861343

1. ISHIJIMA Muneaki (70365576)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. Okada Yasunori (00115221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. デベガスサーナ (30623590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. チレッキメフメット・ゼイネル (10827538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 久保田光昭 (30327796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 根岸貴子 (90451905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 塩澤淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 金子和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 長尾雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 下田将之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 平沢恵理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kaneko Haruka 金子 晴香

KANEKO Haruka 金子 晴香

Research Projects

Research Products

Co-Researchers

Pathophysiology and mechanism of the progression of subchondral bone lesions in knee osteoarthritis

Principal Investigator

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Mechanism analysis and disease inhibition of synovitis and osteophyte formation in knee osteoarthritisPrincipal Investigator

Principal Investigator

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Pathophysiological study and image analysis of early-stage knee OA by focusing on osteochondrophytes

Principal Investigator

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Research Institution

Regulation and mechanisms elucidation of synovitis in knee osteoarthritisPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Regulation of osteophyte formation in knee osteoarthritis by modulating the function of perlecan expressed in synoviumPrincipal Investigator

Principal Investigator

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Research Institution

The functional analysis of perlecan in the late stage of osteophyte formation in knee osteoarthritisPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] IL-6 Reduces Spheroid Sizes of Osteophytic Cells Derived from Osteoarthritis Knee Joint via Induction of Apoptosis2024

Author(s)

Journal Title

DOI

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[Journal Article] Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study2023

Author(s)

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DOI

Data Source

[Journal Article] Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis ? The Bunkyo Health Study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic upregulation of ADAMTS4 (aggrecanase-1) by cytokines and its suppression in knee osteoarthritic synovial fibroblasts2021

Author(s)

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DOI

Data Source

[Journal Article] Medial meniscus extrusion is a determinant factor for the gait speed among MRI-detected structural alterations of knee osteoarthritis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deletion of Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization (HYBID) Results in Attenuation of Osteoarthritis in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Implication of HYBID (Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization) in Hyaluronan Degradation by Synovial Fibroblasts in Patients with Knee Osteoarthritis.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 変形性膝関節症におけるHYBID（CEMIP/KIAA1199）の発現と役割―早期変形性膝関節症のバイオマーカーとしての可能性も含めてー2019

Author(s)

Journal Title

Data Source

Kaneko Haruka 金子晴香

KANEKO Haruka 金子晴香

[Presentation] 早期変形性膝関節症への治療の深化～TKA前にできる治療～　早期変形性膝関節症の病態から考える治療法　半月板と骨棘(シンポジウム)2023