Sakurai Kaori 櫻井香里

… Alternative Names

Researcher Number	50447512
Other IDs
Affiliation (Current)	2021: 東京農工大学, 工学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help	2013 – 2021: 東京農工大学, 工学(系)研究科(研究院), 准教授 2008: Tokyo University of Agriculture and Technology, 大学院共生科学技術研究院, 特任准教授 2007 – 2008: Tokyo University of Agriculture and Technology, 大学院・共生科学技術研究院, 特任准教授
Review Section/Research Field	Principal Investigator Living organism molecular science / Biomolecular chemistry / Bio-related chemistry / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Basic Section 38040:Bioorganic chemistry-related Except Principal Investigator Biomolecular chemistry
Keywords	Principal Investigator フォトアフィニティープローブ / フォトアフィニティーラベリング / 結合タンパク質 / 金ナノ粒子 / 生理活性物質 / 糖脂質 / 分子認識 / 天然物リガンド / OSW-1 / 生物活性分子 … More Except Principal Investigator 脂質二重膜 / 脂質ラフト / スフィンゴミエリン / ドメイン構造 / 古細菌脂質 / 動的配座 / 合成化学 / 全合成 / 天然物 / 生物活性分子の設計 / 生理活性 Less

未知標的タンパク質探索のための新規基盤技術の確立Principal InvestigatorOngoing
- Principal Investigator
  
  櫻井香里
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Tokyo University of Agriculture and Technology
金ナノ粒子を用いた医薬品標的タンパク質の効率的探索法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  櫻井香里
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Tokyo University of Agriculture and Technology
巨大複雑天然物群の網羅的創出による未踏創薬モレキュラースペースの開拓Ongoing
- Principal Investigator
  
  井上将行
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Dynamic conformation and domain structure of lipid molecules in model biomembranesOngoing
- Principal Investigator
  
  村田道雄
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Osaka University
Development of photoaffinity selection system for identification of low abundance proteinsPrincipal Investigator
- Principal Investigator
  
  Kaori Sakurai
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Tokyo University of Agriculture and Technology
Development of an Active/Inactive Dual Probe Photoaffinity Labeling System for Identification of Natural Product Binding ProteinsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Kaori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo University of Agriculture and Technology
Development of Novel Chemical Probes for Bioactive GlycolipidsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Kaori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo University of Agriculture and Technology

All 2020 2019 2018 2017 2016 2015 2014 2008 Other

All Journal Article Presentation

[Journal Article] Interactions of OSW-1 with Lipid Bilayers in Comparison with Digitonin and Soyasaponin.2020
- Author(s)
  Raymond Malabed, Shinya Hanashima, Michio Murata, Kaori Sakurai
- Journal Title
  
  Langmuir
  
  Volume: 36 Pages: 3600-3610
- DOI
  10.1021/acs.langmuir.9b03957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06315
[Journal Article] Phospholipid-Dependent Functions of a Macrocyclic Analogue of the Ion-Channel-Forming Antibiotic Gramicidin A2020
- Author(s)
  Ji Mao, Hiroaki Itoh, Kaori Sakurai, Masayuki Inoue
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 68 Issue: 2 Pages: 173-178
- DOI
  10.1248/cpb.c19-00967
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15704, KAKENHI-PROJECT-17H06110
[Journal Article] Clickable gold nanoparticles for streamlining capture, enrichment and release of alkyne-labelled proteins2019
- Author(s)
  Narita Sho、Kobayashi Naohiro、Mori Kanna、Sakurai Kaori
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Pages: 126768-126768
- DOI
  10.1016/j.bmcl.2019.126768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05331, KAKENHI-PROJECT-17H06110
[Journal Article] Development of Chemical Probes for Functional Analysis of Anticancer Saponin OSW‐12019
- Author(s)
  Komatsu Rina、Sakurai Kaori
- Journal Title
  
  The Chemical Record
  
  Volume: 19 Pages: 2362-2369
- DOI
  10.1002/tcr.201900042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05331, KAKENHI-PROJECT-17H06110
[Journal Article] Anticancer saponin OSW-1 is a novel class of selective Golgi stress inducer2019
- Author(s)
  Kimura Mayu、Sasaki Kanae、Fukutani Yosuke、Yoshida Hiderou、Ohsawa Ikuroh、Yohda Masafumi、Sakurai Kaori
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Pages: 1732-1736
- DOI
  10.1016/j.bmcl.2019.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06645, KAKENHI-PROJECT-19K16131, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-18K14060
[Journal Article] Computational and Experimental Analysis on the Conformational Preferences of Anticancer Saponin OSW-12019
- Author(s)
  Fukaya Keisuke、Urabe Daisuke、Hiraizumi Masato、Noguchi Keiichi、Matsumoto Takashi、Sakurai Kaori
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 85 Pages: 339-344
- DOI
  10.1021/acs.joc.9b02085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06110
[Journal Article] A Peptide–Glycolipid Interaction Probed by Retroinverso Peptide Analogues2018
- Author(s)
  Sakurai Kaori
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 66 Issue: 1 Pages: 45-50
- DOI
  10.1248/cpb.c17-00455
- NAID
  130006301041
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06110
[Journal Article] Synthesis of alkyne-tagged and biotin-tagged Sortin1 as novel photoaffinity probes2018
- Author(s)
  Komatsu, R. Yamaguchi, T. Kobayashi, N. Ozeki, Y. Sakurai, K.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Pages: 1562-1565
- DOI
  10.1016/j.bmcl.2018.03.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05559, KAKENHI-PROJECT-17H06110
[Journal Article] Design and synthesis of small molecule-conjugated photoaffinity nanoprobes for a streamlined analysis of binding proteins2018
- Author(s)
  Sakurai Kaori、Kato Amane、Adachi Keisuke
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Pages: 3227-3230
- DOI
  10.1016/j.bmcl.2018.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06110
[Journal Article] Target Identification of Yaku'amide B and Its Two Distinct Activities against Mitochondrial FoF1-ATP Synthase.2018
- Author(s)
  Kitamura Kai、Itoh Hiroaki、Sakurai Kaori、Dan Shingo、Inoue Masayuki
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 140 Pages: 12189-12199
- DOI
  10.1021/jacs.8b07339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06452, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K15421
[Journal Article] Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3- O -glycosyl saponins2017
- Author(s)
  Malabed Raymond、Hanashima Shinya、Murata Michio、Sakurai Kaori
- Journal Title
  
  BBA Biomembrane
  
  Volume: 1859 Pages: 2516-2525
- DOI
  10.1016/j.bbamem.2017.09.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06315, KAKENHI-PROJECT-15K01801
[Journal Article] Dissecting the structural basis for the intracellular delivery of OSW-1 by fluorescent probes2017
- Author(s)
  Hiraizumi M.、Komatsu R.、Shibata T.、Ohta Y.、Sakurai K.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 15 Pages: 3568-3570
- DOI
  10.1039/c7ob00486a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06110
[Journal Article] Synthesis of a fluorescent photoaffinity probe of OSW-1 by site-selective acylation of an inactive congener and biological evaluation2017
- Author(s)
  Sakurai, K., Hiraizumi, M.,　Isogai, N., Komatsu, R., Shibata, T., Ohta, Y.
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Pages: 517-520
- DOI
  10.1016/j.bmcl.2016.08.053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05559
[Journal Article] Gold Nanoparticle-Based Multivalent Carbohydrate Probes: Selective Photoaffinity Labeling of Carbohydrate-Binding Proteins2016
- Author(s)
  Sakurai, K., Hatai, Y., Okada, A.
- Journal Title
  
  Chem. Sci.
  
  Volume: 7 Pages: 702-706
- DOI
  10.1039/c5sc03275j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05559
[Journal Article] Fluorescent analog of OSW-1 and its cellular localization2014
- Author(s)
  Yamada, R., Takeshita, T., Hiraizumi, M., Shinohe, D., Ohta, Y., Sakurai, K.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 24 Pages: 1839-1842
- DOI
  10.1016/j.bmcl.2014.02.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560400
[Journal Article] Synthesis of OSW-1 Derivatives by Site-Selective Acylation and Their Biological Evaluation2014
- Author(s)
  Sakurai, K., Takeshita, T., Hiraizumi, M., Yamada, R.
- Journal Title
  
  Organic Letters
  
  Volume: 16 Pages: 6318-6321
- DOI
  10.1021/ol503044j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560400
[Journal Article] Comparison of the Reactivity of Carbohydrate Photoaffinity Probes with Different Photoreactive Groups2014
- Author(s)
  Sakurai, K., Ozawa, S., Yamada, R., Yasui, T., Mizuno, S.
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Pages: 1399-1403
- DOI
  10.1002/cbic.201402051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25560400
[Journal Article] DNA テンプレート有機合成法(DTS):生命原理に学ぶ機能性分子創製・探索への新規アプローチ2008
- Author(s)
  Kaori Sakurai, David R. Liu
- Journal Title
  
  有機合成化学協会誌 66
  
  Pages: 590-604
- NAID
  10021175588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710182
[Journal Article] DNAテンプレート有機合成法(DTS) : 生命原理に学ぶ機能性分子創製・探索への新規アプローチ2008
- Author(s)
  Kaori Sakurai, David R. Liu
- Journal Title
  
  有機合成化学協会誌 66
  
  Pages: 590-604
- NAID
  10021175588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710182
[Presentation] Exploration of protein reactive groups for gold-nanoparticle based affinity labeling of carbohydrate binding proteins2020
- Author(s)
  N. Suto, K. Sakurai
- Organizer
  日本化学会第 100 春季年会, 東京理科大学野田キャンパス, 千葉県, 野田市, 2020年 3月22日～3月25日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Ligand-clickable gold nanoparticle probes for photoaffinity labeling2020
- Author(s)
  K. Mori, K. Sakurai
- Organizer
  日本化学会第 100 春季年会, 東京理科大学野田キャンパス, 千葉県, 野田市, 2020年3月22日～3月25日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Evaluation of electrophilic groups for gold nanoparticle-based affinity labeling probes2020
- Author(s)
  S. Kamoshita, N. Suto, K. Sakurai
- Organizer
  日本化学会第 100 春季年会, 東京理科大学野田キャンパス, 千葉県, 野田市, 2020年3月22日～3月25日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold-nanoparticle based probes for target identification and analysis of bioactive small molecules2019
- Author(s)
  Kaori Sakurai,
- Organizer
  Asian Chemical Biology Initiative Yangon Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based click-photocapture agents for target protein identification2019
- Author(s)
  Kanna Mori, Naohiro Kobayashi, Kaori Sakurai
- Organizer
  日本化学会第 99 春季年会
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of Gold Nanoparticle-Based Affinity Labeling Probes for Target Protein Analysis2019
- Author(s)
  Nanako Suto Takumi Umezawa, Kaori Sakurai,
- Organizer
  日本化学会第99回春季年会
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold-nanoparticle based probes for target identification and analysis of bioactive small molecules2019
- Author(s)
  K. Sakurai
- Organizer
  Asian Chemical Biology Initiative Yangon Meeting, Yangon, Myanmar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold nanoparticle-based clickable photoaffinity labeling agent for target protein identification2019
- Author(s)
  K. Mori, N. Kobayashi, K. Sakurai
- Organizer
  第14回ケミカルバイオロジー学会年会, ウインクあいち, 愛知県, 名古屋市, 2019年6月12日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold nanoparticle-based clickable photoaffinity labeling agent for target protein identification2019
- Author(s)
  Kanna Mori, Naohiro Kobayashi, Kaori Sakurai
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based affinity labeling probes for analyzing carbohydrate-binding proteins2019
- Author(s)
  Nanako Suto, Kaori Sakurai
- Organizer
  2nd Australasian Glycoscience Symposium, HUPO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] 金ナノ粒子アフィニティーラベリングプローブの開発2019
- Author(s)
  鴨下潮音、櫻井香里
- Organizer
  Nanotech CUPAL AIST TIA ナノバイオサマースクール
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based affinity labeling probes for target protein analysis2019
- Author(s)
  N. Suto, T. Umezawa, K. Sakurai
- Organizer
  第14回ケミカルバイオロジー学会年会，ウインクあいち, 愛知県, 名古屋市, 2019年6月12日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of Small Molecule-Conjugated Gold Nanoparticle Probes for Target Protein Analysis2019
- Author(s)
  K. Sakurai
- Organizer
  Departmental Seminar, Department of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzen, China, April 19, 2019.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 糖鎖結合タンパク質探索のための金ナノ粒子プローブ開発2019
- Author(s)
  須藤菜々子，櫻井香里
- Organizer
  H30年度 TIAナノバイオスクール(糖鎖・レクチン), お茶ノ水女子大学, 東京都, 文京区, 2019年9月4日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 金ナノ粒子を基盤としたアフィニティ-ラベリングプローブの開発2019
- Author(s)
  須藤菜々子，櫻井香里
- Organizer
  第18回新規素材探索研究会セミナー, 富士ビューホテル, 神奈川県, 横浜市, 2019年6月7日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 金ナノ粒子アフィニティーラベリングプローブの開発2019
- Author(s)
  鴨下潮音，櫻井香里
- Organizer
  H30年度 TIAナノバイオスクール(糖鎖・レクチン), お茶ノ水女子大学, 東京都, 文京区, 2019年9月4日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 糖鎖結合タンパク質探索のための金ナノ粒子プローブ開発2019
- Author(s)
  須藤菜々子、櫻井香里
- Organizer
  Nanotech CUPAL AIST TIA ナノバイオサマースクール
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of Small Molecule-Conjugated Gold Nanoparticle Probes for Target Protein Analysis2019
- Author(s)
  K. Sakurai
- Organizer
  Department of Chemistry, Southern University of Science and Technology, Shenzhen, China, April 18, 2019.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Target Identification: Chemical Approaches2019
- Author(s)
  K. Sakurai
- Organizer
  Asian Chemical Biology Initiative Jakarta Meeting, Jakarta, Indonesia, December 7, 2019.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold nanoparticle-based affinity labeling probes for target protein analysis2019
- Author(s)
  Nanako Suto, Takumi Umezawa, Kaori Sakurai
- Organizer
  日本化学会第 99 春季年会
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] 複雑ペプチド系天然物ヤクアミドBの標的タンパク質同定2019
- Author(s)
  伊藤寛晃, 喜多村佳委, 櫻井香里, 井上将行
- Organizer
  日本ケミカルバイオロジー学会　第14回年会, ウインクあいち, 愛知県, 名古屋市, 2019年6月10日～6月12日
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold nanoparticle-based clickable photoaffinity probes for target protein identification2019
- Author(s)
  Kanna Mori, Kaori Sakurai
- Organizer
  2nd Australasian Glycoscience Symposium, HUPO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold-nanoparticle based probes for target identification and analysis of bioactive small molecules2019
- Author(s)
  K. Sakurai
- Organizer
  Departmental Seminar, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Sweden
- Invited
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold-nanoparticle based probes for target identification and analysis of bioactive small molecules2019
- Author(s)
  Kaori Sakurai,
- Organizer
  Asian Chemical Biology Initiative Yangon Meeting, Yangon, Myanmar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based affinity labeling probes for target protein analysis2019
- Author(s)
  Nanako Suto Takumi Umezawa, Kaori Sakurai,
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based multivalent photoaffinity probes toward exploration of carbohydrate-protein interaction2019
- Author(s)
  Kaori Sakurai
- Organizer
  2nd Australasian Glycoscience Symposium, HUPO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based affinity labeling probes for analyzing carbohydrate-binding proteins2019
- Author(s)
  N. Suto, K. Sakurai
- Organizer
  2nd Australasian Glycoscience Symposium-18th World HUPO Congress, Adelaide, Australia, September 17, 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold nanoparticle-based clickable photoaffinity probes for target protein identification2019
- Author(s)
  K. Mori, K. Sakurai
- Organizer
  2nd Australasian Glycoscience Symposium-18th World HUPO Congress, Adelaide, Australia, September 17, 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of Gold Nanoparticle-Based Click- Photocapture Agents for Target Protein Identification2019
- Author(s)
  Kanna Mori, Naohiro Kobayashi, Kaori Sakurai
- Organizer
  日本化学会第99回春季年会
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold nanoparticle-based multivalent photoaffinity probes toward exploration of carbohydrate-protein interaction2019
- Author(s)
  K. Sakurai
- Organizer
  2nd Australasian Glycoscience Symposium-18th World HUPO Congress, Adelaide Australia, September 16, 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Target identification: Chemical Approaches2019
- Author(s)
  Kaori Sakurai
- Organizer
  Asian Chemical Biology Initiative Jakarta Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of Gold-Nanoparticle Based Probes for Target Identification and Analysis of Bioactive Small Molecules2018
- Author(s)
  K. Sakurai
- Organizer
  A3 Foresight Program Round Table Meeting on Chemical Probe Research Hub, Jeju, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Chemical-probe based approach to binding interaction analysis of anticancer natural product OSW-12018
- Author(s)
  Rina Komatsu, Naho Isogai, Kaori Sakurai
- Organizer
  A3 Foresight Program Young researchers Meeting on Chemical Probe Research Hub
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Chemical Probe-Based Approach to Study Bioactivity of Natural Products2018
- Author(s)
  K. Sakurai
- Organizer
  Departmental Seminar, Academia Sinica, Taipei, Taiwan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of Gold-Nanoparticle Based Probes for Target Identification and Analysis of Bioactive Small Molecules2018
- Author(s)
  Kaori Sakurai,
- Organizer
  A3 Foresight Program Round Table Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Development of gold-nanoparticle based probes for target identification and analysis of bioactive small molecules2018
- Author(s)
  K. Sakurai
- Organizer
  Singapore Chemistry Conference 2018 (SICC-10), Singapore
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 生物活性分子の作用機序解明に向けた標的タンパク質探索法の開発2018
- Author(s)
  櫻井香里
- Organizer
  日本化学会第98春季年会女性科学者が拓く生命化学特別企画公演, 日本大学, 理工学部船橋キャンパス(千葉県船橋市)
- Invited
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 生物活性分子の作用機序解明に向けた標的タンパク質探索法の開発2018
- Author(s)
  櫻井香里
- Organizer
  Asian Chemical Probe Research Hub Symposium天然物有機化学・天然物合成とケミカルバイオロジー, 東北大学(宮城県仙台市)
- Invited
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 生物活性分子の作用機構解明に向けた標的タンパク質探索法2018
- Author(s)
  櫻井香里
- Organizer
  Asian Chemical Probe Research Hub Symposium天然物有機化学・天然物合成とケミカルバイオロジー
- Invited
- Data Source
  KAKENHI-PROJECT-15K05559
[Presentation] 抗癌活性サポニンOSW-1の化学プローブを用いたOSBPパラログ選択的結合活性の解析2018
- Author(s)
  小松莉奈、磯貝菜穂、櫻井香里
- Organizer
  GlycoTokyo 2018
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] Chemical Probe-Based Approach to Study Bioactivity of Natural Products2018
- Author(s)
  K. Sakurai
- Organizer
  Departmental Seminar, Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold-nanoparticle based probes for target identification and analysis of bioactive small molecules2018
- Author(s)
  Kaori Sakurai,
- Organizer
  Singapore Chemistry Conference 2018 (SICC-10)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05331
[Presentation] 抗がん活性天然物ヤクアミドBの標的タンパク質同定2018
- Author(s)
  ○伊藤寛晃、喜多村佳委、櫻井香里、井上将行
- Organizer
  第60回天然有機化合物討論会、久留米シティプラザ、福岡県、久留米市
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 生物活性分子の作用機構解明に向けた標的タンパク質探索法2018
- Author(s)
  櫻井香里
- Organizer
  日本化学会第98春季年会女性科学者が拓く生命化学特別企画公演
- Invited
- Data Source
  KAKENHI-PROJECT-15K05559
[Presentation] Sterol-dependent membrane activity of steroidal saponin OSW-1 using spectroscopic and microscopic approaches2018
- Author(s)
  Malabed Raymond、Hanashima Shinya、Murata Michio、Sakurai Kaori
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16H06315
[Presentation] 生物活性分子の作用機序解明に向けた標的タンパク質探索法の開発2017
- Author(s)
  櫻井香里
- Organizer
  新規素材探索研究会第16回セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15K05559
[Presentation] Cholesterol interaction and membrane-permeabilizing properties of OSW-1 examined by solid-state NMR and fluorescence microscopy2017
- Author(s)
  Malabed Raymond、Hanashima Shinya、Murata Michio、Sakurai Kaori
- Organizer
  日本化学会第97春季年会
- Data Source
  KAKENHI-PROJECT-16H06315
[Presentation] Chemical Probe-Based Approach to Study Bioactivity of Natural Product2017
- Author(s)
  K. Sakurai
- Organizer
  Asian Chemical Biology Initiative Ulaanbaataar Meeting, Ulaanbaataar, Mongolia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of gold nanoparticle-based photoaffinity probes displaying bioactive small-molecule ligands2017
- Author(s)
  Amane Kato, Keisuke Adachi, Yuki Hatai, Kaori Sakurai,
- Organizer
  第９７回日本化学会春季年会
- Place of Presentation
  慶應大学日吉キャンパス（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K05559
[Presentation] 抗がん活性天然物ヤクアミドBの作用機構解明2017
- Author(s)
  喜多村佳委、伊藤寛晃、櫻井香里、井上将行
- Organizer
  第43回反応と合成の進歩シンポジウム、富山国際会議場、富山県富山市
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] Development of Chemical Probes for Studying the Anticancer Activity of　OSW-12017
- Author(s)
  K. Sakurai
- Organizer
  Spanish-Japanese Symposium on Modern Synthetic Methodology, Gijon, Spain
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 生物活性分子の作用機序解明に向けた標的タンパク質探索法の開発2017
- Author(s)
  櫻井香里
- Organizer
  新規素材探索研究会第16回セミナー, 新横浜フジビューホテル(神奈川県横浜市)
- Invited
- Data Source
  KAKENHI-PROJECT-17H06110
[Presentation] 位置選択的モノアシル化反応を用いたOSW-1不活性体の分子プローブの合成2015
- Author(s)
  平泉将登、武下智哉、山田里佳、櫻井香里
- Organizer
  第69回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  横浜国立大学、横浜
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] 位置選択的モノアシル化反応を用いたOSW-1のビオチンプローブの合成と生物活性評価2014
- Author(s)
  武下智哉、平泉将登、山田里佳、櫻井香里
- Organizer
  第67回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  慶応大学、横浜
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] 位置選択的モノアシル化反応を用いたOSW-1のビオチンプローブの合成と生物活性評価2014
- Author(s)
  武下智哉、平泉将登、山田里佳、櫻井香里
- Organizer
  第4回CSJ化学フェスタ2014
- Place of Presentation
  タワーホール船堀, 東京
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] evelopment of Metabolically Stable α-Helical Peptide Inhibitors for Targeting p53-MDM2 Interface2008
- Author(s)
  Kaori Sakurai
- Organizer
  The Mona Symposium, Natural Products and Medicinal Chemistry, the 22nd Meeting
- Place of Presentation
  Mona, Jamaica
- Data Source
  KAKENHI-PROJECT-19710182
[Presentation] Dual-probe photoaffinity labeling strategy for selective detection of small-molecule binding proteins
- Author(s)
  Kaori Sakurai
- Organizer
  10th Japanese-German Frontiers of Science Symposium
- Place of Presentation
  京都ブライトンホテル（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] Fluorescently Labeled OSW-1 and Its Biological Evaluation
- Author(s)
  Rika Yamada, Kaori Sakurai
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  アヤハレークサイドホテル(大津）
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] Fluorescently Labeled OSW-1 and Its Biological Evaluation
- Author(s)
  Rika Yamada, Kaori Sakurai
- Organizer
  第8回ケミカルバイオロジー学会年会
- Place of Presentation
  東京医科歯科大学（東京）
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] フォトアフィニティーラベリングを用いた低分子―タンパク質相互作用解析
- Author(s)
  Kaori Sakurai
- Organizer
  第１３回有機合成化学協会関東支部談話会
- Place of Presentation
  和光純薬工業(株)湯河原研修所（熱海）
- Invited
- Data Source
  KAKENHI-PROJECT-25560400

1. 村田道雄 (40183652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 花島慎弥 (50373353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 梅川雄一 (20587779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 篠田渉 (70357193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 土川博史 (30460992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 三浦薫 (90353515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 井上将行 (70322998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 伊藤寛晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 吉田秀郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐々木桂奈江

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 福谷洋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 旦慎吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakurai Kaori 櫻井 香里

SAKURAI Kaori 櫻井 香里

Research Projects

Research Products

Co-Researchers

未知標的タンパク質探索のための新規基盤技術の確立Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

金ナノ粒子を用いた医薬品標的タンパク質の効率的探索法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

巨大複雑天然物群の網羅的創出による未踏創薬モレキュラースペースの開拓Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic conformation and domain structure of lipid molecules in model biomembranesOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of photoaffinity selection system for identification of low abundance proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an Active/Inactive Dual Probe Photoaffinity Labeling System for Identification of Natural Product Binding ProteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Novel Chemical Probes for Bioactive GlycolipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Interactions of OSW-1 with Lipid Bilayers in Comparison with Digitonin and Soyasaponin.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipid-Dependent Functions of a Macrocyclic Analogue of the Ion-Channel-Forming Antibiotic Gramicidin A2020

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Clickable gold nanoparticles for streamlining capture, enrichment and release of alkyne-labelled proteins2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Chemical Probes for Functional Analysis of Anticancer Saponin OSW‐12019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anticancer saponin OSW-1 is a novel class of selective Golgi stress inducer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational and Experimental Analysis on the Conformational Preferences of Anticancer Saponin OSW-12019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Peptide–Glycolipid Interaction Probed by Retroinverso Peptide Analogues2018

Sakurai Kaori 櫻井香里

SAKURAI Kaori 櫻井香里