SAKURAI Kaori 櫻井香里

Researcher Number	50447512
Other IDs
Affiliation *help	2013 – 2018 : 東京農工大学, 工学(系)研究科(研究院), 准教授 2007 – 2008 : Tokyo University of Agriculture and Technology, 大学院・共生科学技術研究院, 特任准教授 2008 : Tokyo University of Agriculture and Technology, 大学院共生科学技術研究院, 特任准教授
Review Section/Research Field	Principal Investigator Living organism molecular science / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Bio-related chemistry / Biomolecular chemistry Except Principal Investigator Biomolecular chemistry
Keywords	Principal Investigator 金ナノ粒子 / 結合タンパク質 / フォトアフィニティーラベリング / フォトアフィニティラベリング / 光反応基 / OSW-1 / 化学プローブ / 糖脂質 / 生理活性物質 / 天然物リガンド … More Except Principal Investigator ドメイン構造 / 全合成 / 脂質二重膜 / 合成化学 / スフィンゴミエリン / 天然物 / 生物活性分子の設計 / 動的配座 / 脂質ラフト / 生理活性 Less

金ナノ粒子を用いた医薬品標的タンパク質の効率的探索法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  櫻井香里
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Tokyo University of Agriculture and Technology
巨大複雑天然物群の網羅的創出による未踏創薬モレキュラースペースの開拓Ongoing
- Principal Investigator
  
  井上将行
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Dynamic conformation and domain structure of lipid molecules in model biomembranesOngoing
- Principal Investigator
  
  村田道雄
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Osaka University
低発現量タンパク質の探索を可能とするフォトアフィニティーセレクション法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  櫻井香里
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Tokyo University of Agriculture and Technology
Development of an Active/Inactive Dual Probe Photoaffinity Labeling System for Identification of Natural Product Binding ProteinsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Kaori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo University of Agriculture and Technology
Development of Novel Chemical Probes for Bioactive GlycolipidsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Kaori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo University of Agriculture and Technology

All 2017 2016 2015 2014 2008 Other

All Journal Article Presentation

[Journal Article] Gold Nanoparticle-Based Multivalent Carbohydrate Probes: Selective Photoaffinity Labeling of Carbohydrate-Binding Proteins2016
- Author(s)
  Sakurai, K., Hatai, Y., Okada, A.
- Journal Title
  
  Chem. Sci.
  
  Volume : 7 Pages : 702-706
- DOI
  10.1039/C5SC03275J
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05559
[Journal Article] Fluorescent analog of OSW-1 and its cellular localization2014
- Author(s)
  Yamada, R., Takeshita, T., Hiraizumi, M., Shinohe, D., Ohta, Y., Sakurai, K.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume : 24 Pages : 1839-1842
- DOI
  10.1016/j.bmcl.2014.02.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560400
[Journal Article] Comparison of the Reactivity of Carbohydrate Photoaffinity Probes with Different Photoreactive Groups2014
- Author(s)
  Sakurai, K., Ozawa, S., Yamada, R., Yasui, T., Mizuno, S.
- Journal Title
  
  ChemBioChem
  
  Volume : 15 Pages : 1399-1403
- DOI
  10.1002/cbic.201402051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25560400
[Journal Article] Synthesis of OSW-1 Derivatives by Site-Selective Acylation and Their Biological Evaluation2014
- Author(s)
  Sakurai, K., Takeshita, T., Hiraizumi, M., Yamada, R.
- Journal Title
  
  Organic Letters
  
  Volume : 16 Pages : 6318-6321
- DOI
  10.1021/ol503044j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560400
[Journal Article] DNA テンプレート有機合成法(DTS):生命原理に学ぶ機能性分子創製・探索への新規アプローチ2008
- Author(s)
  Kaori Sakurai, David R. Liu
- Journal Title
  
  有機合成化学協会誌 66
  
  Pages : 590-604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710182
[Journal Article] DNAテンプレート有機合成法(DTS) : 生命原理に学ぶ機能性分子創製・探索への新規アプローチ2008
- Author(s)
  Kaori Sakurai, David R. Liu
- Journal Title
  
  有機合成化学協会誌 66
  
  Pages : 590-604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710182
[Presentation] Development of gold nanoparticle-based photoaffinity probes displaying bioactive small-molecule ligands2017
- Author(s)
  Amane Kato, Keisuke Adachi, Yuki Hatai, Kaori Sakurai,
- Organizer
  第９７回日本化学会春季年会
- Place of Presentation
  慶應大学日吉キャンパス（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K05559
[Presentation] 位置選択的モノアシル化反応を用いたOSW-1不活性体の分子プローブの合成2015
- Author(s)
  平泉将登、武下智哉、山田里佳、櫻井香里
- Organizer
  第69回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  横浜国立大学、横浜
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] 位置選択的モノアシル化反応を用いたOSW-1のビオチンプローブの合成と生物活性評価2014
- Author(s)
  武下智哉、平泉将登、山田里佳、櫻井香里
- Organizer
  第67回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  慶応大学、横浜
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] 位置選択的モノアシル化反応を用いたOSW-1のビオチンプローブの合成と生物活性評価2014
- Author(s)
  武下智哉、平泉将登、山田里佳、櫻井香里
- Organizer
  第4回CSJ化学フェスタ2014
- Place of Presentation
  タワーホール船堀, 東京
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] evelopment of Metabolically Stable α-Helical Peptide Inhibitors for Targeting p53-MDM2 Interface2008
- Author(s)
  Kaori Sakurai
- Organizer
  The Mona Symposium, Natural Products and Medicinal Chemistry, the 22nd Meeting
- Place of Presentation
  Mona, Jamaica
- Data Source
  KAKENHI-PROJECT-19710182
[Presentation] Fluorescently Labeled OSW-1 and Its Biological Evaluation
- Author(s)
  Rika Yamada, Kaori Sakurai
- Organizer
  第48回天然物化学談話会
- Place of Presentation
  アヤハレークサイドホテル(大津）
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] フォトアフィニティーラベリングを用いた低分子―タンパク質相互作用解析
- Author(s)
  Kaori Sakurai
- Organizer
  第１３回有機合成化学協会関東支部談話会
- Place of Presentation
  和光純薬工業(株)湯河原研修所（熱海）
- Invited
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] Dual-probe photoaffinity labeling strategy for selective detection of small-molecule binding proteins
- Author(s)
  Kaori Sakurai
- Organizer
  10th Japanese-German Frontiers of Science Symposium
- Place of Presentation
  京都ブライトンホテル（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-25560400
[Presentation] Fluorescently Labeled OSW-1 and Its Biological Evaluation
- Author(s)
  Rika Yamada, Kaori Sakurai
- Organizer
  第8回ケミカルバイオロジー学会年会
- Place of Presentation
  東京医科歯科大学（東京）
- Data Source
  KAKENHI-PROJECT-25560400

1. 村田道雄 (40183652)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
2. 花島慎弥 (50373353)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. 土川博史 (30460992)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 篠田渉 (70357193)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 三浦薫 (90353515)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. 梅川雄一 (20587779)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 井上将行 (70322998)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

SAKURAI Kaori 櫻井 香里

Research Projects

Research Products

Co-Researchers

金ナノ粒子を用いた医薬品標的タンパク質の効率的探索法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

巨大複雑天然物群の網羅的創出による未踏創薬モレキュラースペースの開拓Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic conformation and domain structure of lipid molecules in model biomembranesOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低発現量タンパク質の探索を可能とするフォトアフィニティーセレクション法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an Active/Inactive Dual Probe Photoaffinity Labeling System for Identification of Natural Product Binding ProteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Novel Chemical Probes for Bioactive GlycolipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gold Nanoparticle-Based Multivalent Carbohydrate Probes: Selective Photoaffinity Labeling of Carbohydrate-Binding Proteins2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fluorescent analog of OSW-1 and its cellular localization2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of the Reactivity of Carbohydrate Photoaffinity Probes with Different Photoreactive Groups2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of OSW-1 Derivatives by Site-Selective Acylation and Their Biological Evaluation2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA テンプレート有機合成法(DTS):生命原理に学ぶ機能性分子創製・探索への新規アプローチ2008

Author(s)

Journal Title

Data Source

[Journal Article] DNAテンプレート有機合成法(DTS) : 生命原理に学ぶ機能性分子創製・探索への新規アプローチ2008

Author(s)

Journal Title

Data Source

[Presentation] Development of gold nanoparticle-based photoaffinity probes displaying bioactive small-molecule ligands2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 位置選択的モノアシル化反応を用いたOSW-1不活性体の分子プローブの合成2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 位置選択的モノアシル化反応を用いたOSW-1のビオチンプローブの合成と生物活性評価2014

SAKURAI Kaori 櫻井香里