Shirota Hidekazu 城田英和

Researcher Number	50451555
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2023: 東北大学, 医学系研究科, 准教授 2022: 東北大学, 加齢医学研究所, 准教授 2018 – 2021: 東北大学, 医学系研究科, 准教授 2017: 東北大学, 医学部, 准教授 2016: 東北大学, 医学系研究科, 講師 2013 – 2015: 東北大学, 医学(系)研究科(研究院), 講師
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology
Keywords	Principal Investigator 腫瘍 / T細胞 / 免疫 / マクロファージ / 腫瘍微小環境 / 腫瘍免疫 / DAMPs / 抗体 / Fcレセプター / 癌 … More / CD4 T 細胞 / CD4T細胞 / ヘルパーT細胞 / IL-4 / 癌免疫 / 微小環境 / MDSC Less

生体内の腫瘍細胞死が及ぼす腫瘍微小環境の変化Principal Investigator
- Principal Investigator
  
  城田英和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University
The role of humoral immunity in tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  Shirota Hidekazu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University
IL-4 blockade alters the tumor microenvironment and augments the response to cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  Shirota Hidekazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Analysis of inflammation and immune cells in tumor microenvironment.Principal Investigator
- Principal Investigator
  
  Shirota Hidekazu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Other

[Book] Inflammation / From Molecular and Cellular Mechanisms to the Clinic" (J.-M. Cavaillon, M. Singer, eds.)2018
- Author(s)
  Klinman DM and Shirota H.
- Total Pages
  17
- Publisher
  Wiley-VCH Verlag GmbH & Co. KGaA
- ISBN
  9783527338993
- Data Source
  KAKENHI-PROJECT-16K07106
[Book] Inflammation / From Molecular and Cellular Mechanisms to the Clinic"2016
- Author(s)
  Shirota H and Klinman DM
- Publisher
  Wiley-VCH Verlag GmbH & Co. KGaA,
- Data Source
  KAKENHI-PROJECT-25430103
[Book] Immunopotentiators in Modern Vaccines Second Edition, edited by Dr. Virgil Schijns and Dr. Derek O'Hagan.2016
- Author(s)
  Shirota H and Klinman DM
- Publisher
  Life Science Academic Press/Elsevier.
- Data Source
  KAKENHI-PROJECT-25430103
[Book] Immunopotentiators in Modern Vaccines Second Edition, edited by Dr. Virgil Schijns and Dr. Derek O'Hagan.2016
- Author(s)
  Shirota H and Klinman DM.
- Total Pages
  487
- Publisher
  Science & Technology Books, Life Science Academic Press/Elsevier.
- Data Source
  KAKENHI-PROJECT-16K07106
[Journal Article] Antibiotics May Interfere with Nivolumab Efficacy in Patients with Head and Neck Squamous Cell Carcinoma.2024
- Author(s)
  Ueta R, Imai H, Saijo K, Kawamura Y, Kodera S, Komine K, Ouchi K, Kasahara Y, Taniguchi S, Yoshida Y, Sasaki K, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Oncology.
  
  Volume: 102(3) Issue: 3 Pages: 252-259
- DOI
  10.1159/000533860
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-22K07293
[Journal Article] Dabrafenib and trametinib administration in patients with <i>BRAF</i> V600E/R or non-V600 <i>BRAF</i> mutated advanced solid tumours (BELIEVE, NCCH1901): a multicentre, open-label, and single-arm phase II trial.2024
- Author(s)
  Shimoi T, Sunami K, Tahara M, Nishiwaki S, Tanaka S, Baba E, Kanai M, Kinoshita I, Shirota H, Hayashi H, Nishida N, Kubo T, Mamesaya N, Ando Y, Okita N, Shibata T, Nakamura K, Yamamoto N.
- Journal Title
  
  EClinicalMedicine.
  
  Volume: 69 Pages: 102447-102447
- DOI
  10.1016/j.eclinm.2024.102447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183
[Journal Article] Depth of response may predict clinical outcome in patients with recurrent/metastatic head and neck cancer treated with pembrolizumab-containing regimens.2023
- Author(s)
  Saijo K, Imai H, Ouchi K, Sasaki K, Yoshida Y, Kawamura Y, Taniguchi S, Kasahara Y, Komine K, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Front Oncol.
  
  Volume: 13 Issue: 5 Pages: 1230731-1230731
- DOI
  10.1159/000534747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-22K07293
[Journal Article] Patient survey on cancer genomic medicine in Japan under the national health insurance system.2023
- Author(s)
  Kage H, Akiyama N, Chang H, Shinozaki-Ushiku A, Ka M, Kawata J, Muto M, Okuma Y, Okita N, Tsuchihara K, Kikuchi J, Shirota H, Hayashi H, Kokuryo T, Yachida S, Hirasawa A, Kubo M, Kenmotsu H, Tanabe M, Ushiku T, Muto K, Seto Y, Oda K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 115(3) Issue: 3 Pages: 954-962
- DOI
  10.1111/cas.16065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21H03074
[Journal Article] TP53 Gain-of-Function Mutation is a Poor Prognostic Factor in High-Methylated Metastatic Colorectal Cancer.2023
- Author(s)
  Wakayama S, Ouchi K, Takahashi S, Yamada Y, Komatsu Y, Shimada K, Yamaguchi T, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Clin Colorectal Cancer
  
  Volume: 22(3) Issue: 3 Pages: 327-328
- DOI
  10.1016/j.clcc.2023.06.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21K07169
[Journal Article] Human resources for administrative work to carry out a comprehensive genomic profiling test in Japan.2023
- Author(s)
  Kage H, Oda K, Muto M, Tsuchihara K, Okita N, Okuma Y, Kikuchi J, Shirota H, Hayashi H, Kokuryo T, Sakai D, Hirasawa A, Kubo M, Kenmotsu H, Akiyama N, Shinozaki-Ushiku A, Tanabe M, Ushiku T, Miyagawa K, Seto Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 114(7) Issue: 7 Pages: 3041-3049
- DOI
  10.1111/cas.15833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21H03074
[Journal Article] Management of patients with presumed germline pathogenic variant from tumor-only genomic sequencing: A retrospective analysis at a single facility2023
- Author(s)
  Kawamura Maako.....Yasuda Jun, et al.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 6 Pages: 399-408
- DOI
  10.1038/s10038-023-01133-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07111, KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21K07169
[Journal Article] Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system.2023
- Author(s)
  Umegaki S, Shirota H, Kasahara Y, Iwasaki T, Ishioka C.
- Journal Title
  
  Cancer Sci.
  
  Volume: 114(8) Issue: 8 Pages: 3076-3086
- DOI
  10.1111/cas.15843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183
[Journal Article] Clinical decisions by the molecular tumor board on comprehensive genomic profiling tests in Japan: A retrospective observational study.2023
- Author(s)
  Shirota H, Komine K, Takahashi M, Takahashi S, Miyauchi E, Niizuma H, Tada H, Shimada M, Niihori T, Aoki Y, Sugiyama I, Kawamura M, Yasuda J, Suzuki S, Iwaya T, Saito M, Saito T, Shibata H, Furukawa T, Ishioka C.
- Journal Title
  
  Cancer Med.
  
  Volume: 12(5) Pages: 6170-6181
- DOI
  10.3389/fonc.2023.1230731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21K07169
[Journal Article] FOLFIRI Chemotherapy for Patients With Metastatic Urachal Carcinoma.2023
- Author(s)
  Taniguchi SH, Komine K, Takenaga N, Yoshida Y, Sasaki K, Kawamura Y, Kasahara Y, Ouchi K, Imai H, Saijo K, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 43(12) Issue: 12 Pages: 5699-5704
- DOI
  10.21873/anticanres.16775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21K07169
[Journal Article] [Panel Discussion - Problems in the Cancer Genomic Medicine]2022
- Author(s)
  Ishioka C, Muto M, Yachida S, Shirota H, Hirasawa A, Miyagawa K, Ashizawa K, Kinoshita I, Nishihara H, Matsuura N, Sakurai A.
- Journal Title
  
  Gan To Kagaku Ryoho .
  
  Volume: 49 Pages: 1014-1017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07183
[Journal Article] Clinical decisions by the molecular tumor board on comprehensive genomic profiling tests in Japan: A retrospective observational study2022
- Author(s)
  Shirota Hidekazu、Komine Keigo、Takahashi Masanobu、Takahashi Shin、Miyauchi Eisaku、Niizuma Hidetaka、Tada Hiroshi、Shimada Muneaki、Niihori Tetsuya、Aoki Yoko、Sugiyama Ikuko、Kawamura Maako、Yasuda Jun、Suzuki Shuhei、Iwaya Takeshi、Saito Motonobu、Saito Tsuyoshi、Shibata Hiroyuki、Furukawa Toru、Ishioka Chikashi
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 5 Pages: 6170-6181
- DOI
  10.1002/cam4.5349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07111, KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21K08675
[Journal Article] BRAF and MEK Inhibitor Treatment for Metastatic Undifferentiated Sarcoma of the Spermatic Cord with BRAF V600E Mutation2022
- Author(s)
  Saijo K, Imai H, Katayama H, Fujishima F, Nakamura K, Kasahara Y, Ouchi K, Komine K, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Case Reports
  
  Volume: 15 Issue: 2 Pages: 762-769
- DOI
  10.1159/000526018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183
[Journal Article] Cisplatin Plus Capecitabine After Adjuvant S-1 in Metastatic Gastric Cancer: A Phase II T-CORE1102 Trial2022
- Author(s)
  Yoshioka T, Takahashi M, Sakamoto Y, Okita A, Fukui T, Murakawa Y, Shindo Y, Imai H, Ohori H, Shirota H, Chiba N, Sasahara YI, Nomura T, Fukushima N, Yamaguchi T, Shimodaira H, Ishioka C.
- Journal Title
  
  Anticancer Res.
  
  Volume: 126 Issue: 4 Pages: 2009-20015
- DOI
  10.21873/anticanres.15680
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657, KAKENHI-PROJECT-18K09270, KAKENHI-PROJECT-21K07248
[Journal Article] Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.2022
- Author(s)
  Naito Y, Sunami K, Kage H, Komine K, Amano T, Imai M, Koyama T, Ennishi D, Kanai M, Kenmotsu H, Maeda T, Morita S, Sakai D, Watanabe K, Shirota H, Kinoshita I, Yoshioka M, Mamesaya N, Ito M, Kohsaka S, Saigusa Y, Yamamoto K, Hirata M, Tsuchihara K, Yoshino T.
- Journal Title
  
  JAMA Netw Open.
  
  Volume: 5 Issue: 12 Pages: 2245081-2245081
- DOI
  10.1001/jamanetworkopen.2022.45081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] [Cooperative Tasks among Cancer Genome Medicine Facilities]2022
- Author(s)
  Shirota H
- Journal Title
  
  Gan To Kagaku Ryoho .
  
  Volume: 49 Pages: 997-999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07183
[Journal Article] Antibiotic Treatment Improves the Efficacy of Oxaliplatin-Based Therapy as First-Line Chemotherapy for Patients with Advanced Gastric Cancer: A Retrospective Study2022
- Author(s)
  Imai H, Saijo K, Komine K, Ueta R, Numakura R, Wakayama S, Umegaki S, Hiraide S, Kawamura Y, Kasahara Y, Ohuchi K, Takahashi M, Takahashi S, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Cancer Manag Res
  
  Volume: 14 Pages: 1259-1266
- DOI
  10.2147/cmar.s353432
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] エキスパートパネル運営上の課題.2021
- Author(s)
  城田英和
- Journal Title
  
  腫瘍内科
  
  Volume: 27 Pages: 39-42
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Phase II study of trifluridine/tipiracil (TAS-102) therapy in elderly patients with colorectal cancer (T-CORE1401): geriatric assessment tools and plasma drug concentrations as possible predictive biomarkers.2021
- Author(s)
  2.Takahashi M，Sakamoto Y，Ohori H，Tsuji Y，Kuroki M，Kato S，Otsuka K，Komine K，Takahashi M，Takahashi S，Shirota H，Ouchi K，Takahashi Y，Imai H，Shibata H，Yoshioka T，Tanaka M，Yamaguchi H，Yamaguchi T，Shimodaira H，Ishioka C.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 88 Issue: 3 Pages: 393-402
- DOI
  10.1007/s00280-021-04277-3
- NAID
  120007169385
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657, KAKENHI-PROJECT-18K09270, KAKENHI-PROJECT-21K07248
[Journal Article] Patients' understanding of communication about palliative care and health condition in Japanese patients with unresectable or recurrent cancer: a cross-sectional survey2021
- Author(s)
  Yusuke Hiratsuka, Takayuki Oishi, Mitsunori Miyashita, Tatsuya Morita, Jennifer W Mack, Masahiro Takahashi, Hidekazu Shirota, Kazunori Otsuka, Chikashi Ishioka, Akira Inoue
- Journal Title
  
  Ann Palliat Med
  
  Volume: 10 Issue: 3 Pages: 2650-2661
- DOI
  10.21037/apm-20-2045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657, KAKENHI-PROJECT-18H03572, KAKENHI-PROJECT-17H04149
[Journal Article] Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei.2020
- Author(s)
  Hiraide S，Komine K，Sato Y，Ouchi K，Imai H，Saijo K，Takahashi M，Takahashi S，Shirota H，Takahashi M，Ishioka C.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 25 Issue: 4 Pages: 774-781
- DOI
  10.1007/s10147-019-01592-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] A phase 2 basket trial of combination therapy with trastuzumab and pertuzumab in patients with solid cancers harboring human epidermal growth factor receptor 2 amplification (JUPITER trial)2020
- Author(s)
  K. Takahashi, E. Ishibashi, T. Kubo, Y. Harada, H. Hayashi, M. Kano, Y. Shimizu, H. Shirota, Y. Mori, M. Muto, C. Ishioka, H. Dosaka-Akita, H. Matsubara, H. Nishihara, N. Sueoka-Aragane, S. Toyooka, A. Hirakawa, U. Tateishi, S. Miyake, S. Ikeda
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 99 Issue: 32 Pages: e21457-e21457
- DOI
  10.1097/md.0000000000021457
- NAID
  120006888498
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] がんゲノム医療中核拠点病院と連携の取り組み．2020
- Author(s)
  城田英和，小峰啓吾．
- Journal Title
  
  癌と化学療法
  
  Volume: 47 Pages: 1149-1152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Antibiotics Improve the Treatment Efficacy of Oxaliplatin-Based but Not Irinotecan-Based Therapy in Advanced Colorectal Cancer Patients.2020
- Author(s)
  Imai H，Saijo K，Komine K，Yoshida Y，Sasaki K，Suzuki A，Ouchi K，Takahashi M，Takahashi S，Shirota H，Takahashi M，Ishioka C.
- Journal Title
  
  Hindawi Journal of Oncology
  
  Volume: 0 Pages: 1701326-1701326
- DOI
  10.1155/2020/1701326
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Contribution of Fcγ receptor IIB to creating a suppressive tumor microenvironment in a mouse model.2019
- Author(s)
  Kasahara Y, Shirota H, Umegaki S, Ishioka C.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 68 Issue: 11 Pages: 1769-1778
- DOI
  10.1007/s00262-019-02413-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Antibiotic therapy augments the efficacy of gemcitabine-containing regimens for advanced cancer: a retrospective study.2019
- Author(s)
  Imai H, Saijo K, Komine K, Otsuki Y, Ohuchi K, Sato Y, Okita A, Takahashi M, Takahashi S, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Cancer Manag Res.
  
  Volume: 11 Pages: 7953-7965
- DOI
  10.2147/cmar.s215697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Therapeutic Benefits of Ipilimumab among Japanese Patients with Nivolumab-Refractory Mucosal Melanoma: A Case Series Study.2019
- Author(s)
  Saijo K, Imai H, Ouchi K, Okada Y, Sato Y, Komine K, Takahashi M, Takahashi S, Shirota H, Takahashi M, Ishioka C.
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume: 248 Issue: 1 Pages: 37-43
- DOI
  10.1620/tjem.248.37
- NAID
  130007650909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Interinstitutional Collaboration for Molecular Tumor Boards2019
- Author(s)
  Komine K, Shirota H.
- Journal Title
  
  Gan To Kagaku Ryoho.
  
  Volume: 46 Pages: 626-629
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07657
[Journal Article] Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer.2018
- Author(s)
  Nie Y, He J, Shirota H, Trivett AL, Yang, Klinman DM, Oppenheim JJ, Chen X.
- Journal Title
  
  Sci Signal.
  
  Volume: 11(511) Issue: 511
- DOI
  10.1126/scisignal.aan0790
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Journal Article] Efficacy and Safety of Trastuzumab in Combination with S-1 and Cisplatin Therapy for Japanese Patients with HER2-Positive Advanced Gastric Cancer: Retrospective Analysis2018
- Author(s)
  Okita Akira、Imai Hiroo、Takahashi Masahiro、Takahashi Hidekazu、Umegaki Sho、Kawamura Yoshifumi、Hiraide Sakura、Ouchi Kota、Sato Yuko、Okada Yoshinari、Komine Keigo、Saijo Ken、Takahashi Shin、Takahashi Masanobu、Shirota Hidekazu、Ohori Hisatsugu、Gamoh Makio、Ishioka Chikashi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 245 Issue: 2 Pages: 123-129
- DOI
  10.1620/tjem.245.123
- NAID
  130007399382
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07106
[Journal Article] Consensus molecular subtypes classification of colorectal cancer2018
- Author(s)
  Okita, A.，Takahashi, S.，Ouchi, K.，Inoue, M.，Yamada, Y.，Ishioka, C.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 4 Pages: 18698-18711
- DOI
  10.1007/s10147-018-1261-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04307, KAKENHI-PROJECT-16K07106
[Journal Article] Predictive factors for the efficacy of the second taxane treatment in patients with advanced cancer2018
- Author(s)
  Imai Hiroo、Saijo Ken、Komine Keigo、Kawamura Yoshifumi、Hiraide Sakura、Umegaki Sho、Okada Yoshinari、Ouchi Kota、Sato Yuko、Takahashi Masahiro、Takahashi Shin、Shirota Hidekazu、Takahashi Masanobu、Ishioka Chikashi
- Journal Title
  
  Cancer Management and Research
  
  Volume: Volume 10 Pages: 3629-3636
- DOI
  10.2147/cmar.s170948
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07106
[Journal Article] The G8 screening tool enhances prognostic value to ECOG performance status in elderly cancer patients: A retrospective, single institutional study.2017
- Author(s)
  Takahashi M, Takahashi M, Komine K, Yamada H, Kasahara Y, Chikamatsu S, Okita A, Ito S, Ouchi K, Okada Y, Imai H, Saijo K, Shirota H, Takahashi S, Mori T, Shimodaira H, Ishioka C.
- Journal Title
  
  PLoS One.
  
  Volume: 12(6) Issue: 6 Pages: e0179694-e0179694
- DOI
  10.1371/journal.pone.0179694
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106, KAKENHI-PROJECT-16K19304, KAKENHI-PROJECT-15K08962, KAKENHI-PROJECT-16K10488
[Journal Article] IL-4 blockade alters the tumor microenvironment and augments the response to cancer immunotherapy in a mouse model.2017
- Author(s)
  Ito SE, Shirota H, Kasahara Y, Saijo K, Ishioka C.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 66(11) Issue: 11 Pages: 1485-1496
- DOI
  10.1007/s00262-017-2043-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Journal Article] Efficacy and safety of gemcitabine plus docetaxel in Japanese patients with unresectable or recurrent bone and soft tissue sarcoma: Results from a single-institutional analysis.2017
- Author(s)
  Takahashi M, Komine K, Imai H, Okada Y, Saijo K, Takahashi M, Shirota H, Ohori H, Takahashi S, Chiba N, Mori T, Shimodaira H, Ishioka C.
- Journal Title
  
  PLoS One.
  
  Volume: 12(5) Issue: 5 Pages: e0176972-e0176972
- DOI
  10.1371/journal.pone.0176972
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106, KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-15K08962, KAKENHI-PROJECT-16K10488
[Journal Article] IL4 from T follicular helper cells downregulates antitumor immunity.2017
- Author(s)
  Shirota H, Klinman DM, Ito S, Ito H, Kubo M, Ishioka C.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 5 Issue: 1 Pages: 61-71
- DOI
  10.1158/2326-6066.cir-16-0113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-16K07106
[Journal Article] Attainment of a Long-term Favorable Outcome by Sunitinib Treatment for Pancreatic Neuroendocrine Tumor and Renal Cell Carcinoma Associated with von Hippel-Lindau Disease2016
- Author(s)
  Kobayashi A, Takahashi M, Imai H, Akiyama S, Sugiyama S, Komine K, Saijo K, Takahashi M, Takahashi S, Shirota H, Sato N, Fujishima F, Shuin T, Shimodaira H, Ishioka C.
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 6 Pages: 629-634
- DOI
  10.2169/internalmedicine.55.5796
- NAID
  130005138072
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103, KAKENHI-PROJECT-26460958, KAKENHI-PROJECT-16K07106
[Journal Article] Efficacy and Safety Assessment of Paclitaxel in Patients with Docetaxel-Resistant Esophageal Squamous Cell Carcinoma.2016
- Author(s)
  Imai H, Komine K, Takahashi S, Saijo K, Okada Y, Kobayashi A, Okita A, Chikamatsu S, Kasahara Y, Takahashi M, Oishi T, Shirota H, Takahashi M, Shimodaira H, Ishioka C
- Journal Title
  
  Chemotherapy
  
  Volume: 61（5） Pages: 262-268
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] Efficacy and Safety of Carboplatin and Etoposide Combination Chemotherapy for Extrapulmonary Neuroendocrine Carcinoma: A Retrospective Case Series.2016
- Author(s)
  Imai H, Shirota H, Okita A, Komine K, Saijo K, Takahashi M, Takahashi S, Takahashi M, Shimodaira H, Ishioka C.
- Journal Title
  
  Chemotherapy
  
  Volume: 61（３） Issue: 3 Pages: 111-116
- DOI
  10.1159/000441551
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103, KAKENHI-PROJECT-26460958, KAKENHI-PROJECT-16K07106
[Journal Article] Effect of TLR agonists on the differentiation and function of human monocytic myeloid-derived suppressor cells.2015
- Author(s)
  Wang J, Shirota Y, Bayik D, Shirota H, Tross D, Gulley JL, Wood LV, Berzofsky JA, Klinman DM
- Journal Title
  
  J Immunol
  
  Volume: 194（９） Issue: 9 Pages: 4215-4221
- DOI
  10.4049/jimmunol.1402004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] Effect of TLR Agonists on the Differentiation and Function of Human Monocytic Myeloid-Derived Suppressor Cells.2015
- Author(s)
  Wang J, Shirota Y, Bayik D, Shirota H, Tross D, Gulley JL, Wood LV, Berzofsky JA, Klinman DM
- Journal Title
  
  J Immunol.
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] CpG Oligonucleotides as Cancer Vaccine Adjuvants.2015
- Author(s)
  Shirota H, Tross D, Klinman DM
- Journal Title
  
  Vaccines (Basel).
  
  Volume: 3（２） Issue: 2 Pages: 390-407
- DOI
  10.3390/vaccines3020390
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] TLR-9 Agonist Immunostimulatory Sequence Adjuvants Linked to Cancer Antigens.2014
- Author(s)
  Shirota H, Klinman DM.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1139 Pages: 337-344
- DOI
  10.1016/j.jaut.2014.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] Recent progress concerning CpG DNA and its use as a vaccine adjuvant.2014
- Author(s)
  Shirota H, Klinman DM.
- Journal Title
  
  Expert Rev Vaccines.
  
  Volume: 13(2) Pages: 299-312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice.2014
- Author(s)
  Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, Schaughency PM, Shirota H, Scarzello AJ, Subleski JJ, Anver MR, Ortaldo JR, Lin F, Reynolds DA, Sanford ME, Kaldis P, Tessarollo L, Klinman DM, Young HA.
- Journal Title
  
  J Autoimmun.
  
  Volume: 53 Pages: 33-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] TLR-9 agonist immunostimulatory sequence adjuvants linked to cancer antigens.2014
- Author(s)
  Shirota H, Klinman DM.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1139 Pages: 337-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] β-Defensin 2 and 3 Promote the Uptake of Self or CpG DNA, Enhance IFN-α Production by Human Plasmacytoid Dendritic Cells, and Promote Inflammation.2013
- Author(s)
  Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, Howard OM, Shirota H, Steinhagen F, Klinman DM, Yang D, Oppenheim JJ.
- Journal Title
  
  J Immunol.
  
  Volume: 191(2) Issue: 2 Pages: 865-874
- DOI
  10.4049/jimmunol.1201648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Journal Article] Use of CpG oligonucleotides for cancer immunotherapy and their effect on immunity in the tumor microenvironment.2013
- Author(s)
  Shirota H, Klinman DM.
- Journal Title
  
  Immunotherapy
  
  Volume: 5(8) Issue: 8 Pages: 787-789
- DOI
  10.2217/imt.13.70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] 免疫チェックポイント阻害薬と免疫関連有害事象（irAE)2022
- Author(s)
  城田英和
- Organizer
  Autoimmune Disease Webinar．Webinar
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] がんゲノム医療の地域連携2022
- Author(s)
  城田英和
- Organizer
  気仙沼がんゲノム医療セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] がんゲノム診療アクセス改善の期待と課題．2022
- Author(s)
  城田英和
- Organizer
  東北がんゲノム実践セミナー2022
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] がんとゲノムの基礎知識について．2022
- Author(s)
  城田英和
- Organizer
  がんゲノム医療医療従事者養成WEB研修会．
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] 東北大学病院エキスパートパネルにおける1003人のがん遺伝子パネル検査の治療提案．2022
- Author(s)
  城田英和，小峰啓吾，高橋雅信，高橋信，宮内栄作，新妻秀剛，多田寛，島田宗昭，新堀哲也，青木洋子，杉山育子，川村真亜子，安田純，鈴木修平，岩谷岳，齋藤元伸，斎藤毅，柴田浩行，古川徹，石岡千加史．
- Organizer
  第20回日本臨床腫瘍学会学術集会．
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] がんゲノム医療総論2022
- Author(s)
  城田英和
- Organizer
  がんゲノム医療医師限定WEB研修会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] がん遺伝子パネル検査のアップデート2022
- Author(s)
  城田英和
- Organizer
  2022年第3回度遺伝子診療部教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] 東北大学病院個別化医療センターの活動．2022
- Author(s)
  城田英和
- Organizer
  第11回東北大学病院次世代医療開発セミナー「がん医療開発の新潮流」．
- Invited
- Data Source
  KAKENHI-PROJECT-22K07183
[Presentation] Prospective study of susceptibility to Pembrolizumab based on gene expression profile in metastatic colorectal cancer．2020
- Author(s)
  笠原佑記，城田英和，石岡千加史
- Organizer
  JSMO/ASCO Young Oncologist Workshop 2020
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] がんゲノム医療の最新情報～当院での消化器癌を含む癌腫別治療提案について～．2020
- Author(s)
  城田英和
- Organizer
  T-CORE college 2021
- Invited
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] HSVtk遺伝子導入がん細胞を用いた生体内のアポトーシス細胞に対する免疫応答の解析2020
- Author(s)
  梅垣翔，城田英和，石岡千加史
- Organizer
  第53回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] がんゲノム医療の現状と実際．2020
- Author(s)
  城田英和
- Organizer
  第53回福島造血幹細胞移植治療研究会．
- Invited
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] がんゲノム医療について．2020
- Author(s)
  城田英和
- Organizer
  第53回東北脳腫瘍研究会．
- Invited
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] がんゲノム医療について．2020
- Author(s)
  城田英和
- Organizer
  小児血液・がんセミナー in 東北．
- Invited
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] がんゲノム医療の現状と実際2020
- Author(s)
  城田英和
- Organizer
  第52回日本臨床分子形態学会総会・学術集会．
- Invited
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic tumor cells induce anti-tumor immunity．2020
- Author(s)
  Umegaki S，Shirota H，Ishioka C．
- Organizer
  AACR Virtual Annual Meeting Ⅱ．
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] Contribution of FcγRIIB to creating a suppressive tumor microenvironment．2019
- Author(s)
  笠原佑記，城田英和，石岡千加史
- Organizer
  第151回東北大学加齢医学研究所集談会．仙台
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] Contribution of FcγRIIB to creating a suppressive tumor microenvironment．2019
- Author(s)
  笠原佑記，城田英和，石岡千加史.
- Organizer
  第151回東北大学加齢医学研究所集談会．仙台
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] CpG ODN と TGF β阻害剤を併用する新規がん免疫療法の開発．2019
- Author(s)
  梅垣翔，城田英和，石岡千加史
- Organizer
  第52回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] Contribution of FcγRIIB to creating a suppressive tumor microenvironment．2019
- Author(s)
  笠原佑記，城田英和，石岡千加史
- Organizer
  平成30年度先端モデル動物支援プラットフォーム成果発表会．滋賀県．
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 網羅的遺伝子発現解析による進行・再発大腸癌の免疫学的特徴の検討2019
- Author(s)
  笠原佑記，城田英和，石岡千加史
- Organizer
  第2回腫瘍内科医交流セミナー．福岡
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] Contribution of FcγRIIB to creating a suppressive tumor microenvironment．2019
- Author(s)
  笠原佑記，城田英和，石岡千加史.
- Organizer
  平成30年度先端モデル動物支援プラットフォーム成果発表会．滋賀県
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] TGF-beta blockade enhances the immunotherapeutic effect of CpG DNA in cancer2019
- Author(s)
  梅垣翔，城田英和，石岡千加史
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07657
[Presentation] Contribution of FcγRIIB to creating suppressive tumor micrienvironment．2018
- Author(s)
  Kasahara, Y.，Shirota, H.，Ishioka, C.
- Organizer
  AACR annual meeting 2018　Chicago, USA．
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 東北大学における未来型医療創生とがんゲノム医療への取り組み2018
- Author(s)
  城田英和，小峰啓吾，石岡千加史
- Organizer
  第 16 回日本臨床腫瘍学会学術集会、神戸
- Invited
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] FcγRIIB の抑制性腫瘍微小環境形成への役割2018
- Author(s)
  笠原佑記，城田英和，石岡千加史
- Organizer
  第77回日本癌学会学術総会．大阪
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 腫瘍微小環境におけるFCγRIIBの役割2018
- Author(s)
  笠原佑記，城田英和，石岡千加史
- Organizer
  第22回日本がん分子標的治療学会学術集会、東京
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 大腸癌網羅的遺伝子発現解析による免疫学的な検討2017
- Author(s)
  笠原佑記、城田英和、井上正広、高橋信、石岡千加史
- Organizer
  第114回日本内科学会総会・講演会
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] FcγIIBの腫瘍微小環境形成への役割2017
- Author(s)
  笠原佑記、城田英和、石岡千加史
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 濾胞性ヘルパーT細胞から産生されるIL-4は抗腫瘍免疫を抑制する2017
- Author(s)
  城田英和、伊藤祝栄、石岡千加史
- Organizer
  第19回日本がん分子標的治療学会学術集会（国際学会）
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] IL-4 modulate the tumor microenvironment and response to cancer therapies2016
- Author(s)
  AI Shuku-ei, H Shirota, C Ishioka
- Organizer
  AACR 107th Annual Meeting 2016
- Place of Presentation
  New Orleans, LA、USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 大腸癌網羅的遺伝子発現解析による免疫学的な検討2016
- Author(s)
  笠原佑記、城田英和、井上正広、高橋信、石岡千加史
- Organizer
  第54回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] 腫瘍微小環境におけるIL-4の役割と抗腫瘍治療効果2016
- Author(s)
  伊藤祝栄、城田　英和、石岡千加史
- Organizer
  第2０回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター　大分
- Year and Date
  2016-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] IL-4 derived from T follicular helper cells in tumor draining lymph nodes regulate myeloid cell properties and anti-tumor immunity2016
- Author(s)
  Hidekazu Shirota, Dennis M. Klinman, Shuku-ei A. Ito, and Chikashi Ishioka
- Organizer
  AACR 107th Annual Meeting 2016
- Place of Presentation
  New Orleans, LA、USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07106
[Presentation] IL-4 derived from T follicular helper cells in tumor draining2015
- Author(s)
  Hidekazu Shirota, Dennis Klinman, Shukuei Ito, Chikashi Ishioka
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] Effect of TLR Ligation on the differentiation and Function of Human mMDSC2015
- Author(s)
  Hidekazu Shirota
- Organizer
  第19回日本がん免疫学会総会、第23回マクロファージ分子細胞生物学国際シンポジウム
- Place of Presentation
  伊藤国際学術研究センター　伊藤謝恩ホール(東京)
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] IL-4 modulate the tumor microenvironment and response to2015
- Author(s)
  Shukuei Ito, Hidekazu Shirota, Chikashi Ishioka
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] Oligodeoxynucleotides expressing Poly-G motifs promote anti-tumor activity through the up-regulation of IL-22014
- Author(s)
  Shirota H
- Organizer
  Keystone Symposia, Immune Evolution in Cancer
- Place of Presentation
  Wistler, Canada
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] Title: Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells2013
- Author(s)
  Shirota H
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] Intra-tumoral injection of CpG ODN induces the differentiation and reduces the immunosuppressive activity of　MDSC2013
- Author(s)
  Shirota H
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] R848 induces Human Myeloid Derived Suppressor Cells into Non-Suppressive M1-like Macrophages2013
- Author(s)
  城田英和
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] Effect of TLR Agonists on the Differentiation and Function of Human Monocytic Myeloid-Derived Suppressor Cells.
- Author(s)
  城田英和
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市、パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25430103
[]

1. Ito Hiroyasu (80373075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. TAKAHASHI Masanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. TAKAHASHI Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. OUCHI Kota

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. OKITA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 伊藤信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 安田純

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 石岡千加史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shirota Hidekazu 城田 英和

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生体内の腫瘍細胞死が及ぼす腫瘍微小環境の変化Principal Investigator

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The role of humoral immunity in tumor microenvironmentPrincipal Investigator

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IL-4 blockade alters the tumor microenvironment and augments the response to cancer immunotherapyPrincipal Investigator

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Analysis of inflammation and immune cells in tumor microenvironment.Principal Investigator

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[Book] Inflammation / From Molecular and Cellular Mechanisms to the Clinic" (J.-M. Cavaillon, M. Singer, eds.)2018

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[Book] Inflammation / From Molecular and Cellular Mechanisms to the Clinic"2016

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[Book] Immunopotentiators in Modern Vaccines Second Edition, edited by Dr. Virgil Schijns and Dr. Derek O'Hagan.2016

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[Book] Immunopotentiators in Modern Vaccines Second Edition, edited by Dr. Virgil Schijns and Dr. Derek O'Hagan.2016

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[Journal Article] Antibiotics May Interfere with Nivolumab Efficacy in Patients with Head and Neck Squamous Cell Carcinoma.2024

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[Journal Article] Dabrafenib and trametinib administration in patients with <i>BRAF</i> V600E/R or non-V600 <i>BRAF</i> mutated advanced solid tumours (BELIEVE, NCCH1901): a multicentre, open-label, and single-arm phase II trial.2024

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[Journal Article] Depth of response may predict clinical outcome in patients with recurrent/metastatic head and neck cancer treated with pembrolizumab-containing regimens.2023

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[Journal Article] Patient survey on cancer genomic medicine in Japan under the national health insurance system.2023

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[Journal Article] Human resources for administrative work to carry out a comprehensive genomic profiling test in Japan.2023

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[Journal Article] Management of patients with presumed germline pathogenic variant from tumor-only genomic sequencing: A retrospective analysis at a single facility2023

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Shirota Hidekazu 城田英和