Okazaki IlMi 岡崎一美

… Alternative Names

OKAZAKI Il-mi 岡崎一美

CHON Il-Mi 鄭一美

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Researcher Number	50452339
Other IDs
Affiliation (Current)	2025: 東京大学, 定量生命科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京大学, 定量生命科学研究所, 准教授 2019: 徳島大学, 先端酵素学研究所(プロテオ), 非常勤講師 2018: 徳島大学, 先端酵素学研究所(プロテオ), 准教授 2016: 徳島大学, 先端酵素学研究所(プロテオ), 准教授 2015: 徳島大学, 疾患プロテオゲノム研究センター, 准教授 2009 – 2010: 徳島大学, 疾患ゲノム研究センター, 助教 2009: 徳島大, 助教
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related / Basic Section 48040:Medical biochemistry-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 自己免疫疾患 / 抑制性免疫補助受容体 / アレルギー / 免疫偏向性 / LAG-3 / 免疫ドミナンス / 連鎖解析 / PD-1 / 単一細胞発現解析 / 突然変異 … More / がん / 免疫学 / 発がん / 炎症 / 実験動物 / 細胞 / 遺伝子 … More Except Principal Investigator 癌 / ゲノム / 抗体 / 免役学 / マイクロアレイ法 / 免疫沈降法 / ウラシルDNAグリコシラーゼ / RNA編集 / 体細胞突然変異 / クラススイッチ Less

Regulatory mechanism of allergic disease development by inhibitory co-receptorsPrincipal Investigator
- Principal Investigator
  
  岡崎一美
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokyo
Elucidating molecular mechanisms of the regulation of immunodominancePrincipal Investigator
- Principal Investigator
  
  Okazaki Il-mi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  The University of Tokyo
Genetic analysis of autoimmune myocarditisPrincipal Investigator
- Principal Investigator
  
  OKAZAKI Il-mi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  The University of Tokushima
Regulatory mechanisms of autoimmunity by LAG-3 expressing cellsPrincipal Investigator
- Principal Investigator
  
  OKAZAKI Il-mi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima
Roles of PD-1 and AIDA in inflammation-induced tumorigenesis.Principal Investigator
- Principal Investigator
  
  OKAZAKI Il-mi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima
AID-dependent genetic alteration mechanism to generate antigen-specific antibodies
- Principal Investigator
  
  HONJO Tasuku
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

All 2022 2021 2020 2019 2018 2017 2016 2015 2011 2010 2009 2007 2006 Other

All Journal Article Presentation Book

[Book] Role of AID in tumorigenesis.,Vol.942007
- Author(s)
  Okazaki, I., Kotani, A. Honjo, T.
- Publisher
  ELSEVIER, Adv. Immunol.
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity2022
- Author(s)
  Sugiura Daisuke、Okazaki Il-mi、Maeda Takeo K.、Maruhashi Takumi、Shimizu Kenji、Arakaki Rieko、Takemoto Tatsuya、Ishimaru Naozumi、Okazaki Taku
- Journal Title
  
  Nature Immunology
  
  Volume: 23 Issue: 3 Pages: 399-410
- DOI
  10.1038/s41590-021-01125-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09859, KAKENHI-PROJECT-17H03607, KAKENHI-PLANNED-18H05415, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029, KAKENHI-PROJECT-19H01070, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-21K06526, KAKENHI-PROJECT-21K07076, KAKENHI-PROJECT-21K19270, KAKENHI-PROJECT-21K19605
[Journal Article] Binding of LAG-3 to stable peptide-MHC class II limits T?cell function and suppresses autoimmunity and anti-cancer immunity2022
- Author(s)
  Maruhashi Takumi、Sugiura Daisuke、Okazaki Il-mi、Shimizu Kenji、Maeda Takeo K.、Ikubo Jun、Yoshikawa Harunori、Maenaka Katsumi、Ishimaru Naozumi、Kosako Hidetaka、Takemoto Tatsuya、Okazaki Taku
- Journal Title
  
  Immunity
  
  Volume: - Issue: 5 Pages: 912-924
- DOI
  10.1016/j.immuni.2022.03.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-21K07076, KAKENHI-PROJECT-19H01070, KAKENHI-PROJECT-21K19270, KAKENHI-PROJECT-21K19605, KAKENHI-PLANNED-18H05415, KAKENHI-PROJECT-21K06526
[Journal Article] T-cell-intrinsic and -extrinsic regulation of PD-1 function2021
- Author(s)
  Sugiura Daisuke、Shimizu Kenji、Maruhashi Takumi、Okazaki Il-mi、Okazaki Taku
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 693-698
- DOI
  10.1093/intimm/dxab077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-21K06526, KAKENHI-PROJECT-21K07076
[Journal Article] PD-1 preferentially inhibits the activation of low-affinity T cells2021
- Author(s)
  Shimizu Kenji、Sugiura Daisuke、Okazaki Il-mi、Maruhashi Takumi、Takemoto Tatsuya、Okazaki Taku
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 35
- DOI
  10.1073/pnas.2107141118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03607, KAKENHI-PLANNED-18H05415, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-21K06526, KAKENHI-PROJECT-21K07076, KAKENHI-PROJECT-21K19270
[Journal Article] PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation2020
- Author(s)
  Shimizu Kenji、Sugiura Daisuke、Okazaki Il-mi、Maruhashi Takumi、Takegami Yujiro、Cheng Chaoyang、Ozaki Soichi、Okazaki Taku
- Journal Title
  
  Molecular Cell
  
  Volume: 77 Issue: 5 Pages: 937-950
- DOI
  10.1016/j.molcel.2019.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-19K16522, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029
[Journal Article] LAG-3: from molecular functions to clinical applications2020
- Author(s)
  Maruhashi Takumi、Sugiura Daisuke、Okazaki Il-mi、Okazaki Taku
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 8 Issue: 2 Pages: e001014-e001014
- DOI
  10.1136/jitc-2020-001014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-19K16694
[Journal Article] Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation2019
- Author(s)
  Maeda Takeo K.、Sugiura Daisuke、Okazaki Il-mi、Maruhashi Takumi、Okazaki Taku
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 15 Pages: 6017-6026
- DOI
  10.1074/jbc.ra119.007455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417
[Journal Article] PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation2019
- Author(s)
  Mizuno Reina、Sugiura Daisuke、Shimizu Kenji、Maruhashi Takumi、Watada Mizuki、Okazaki Il-mi、Okazaki Taku
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 630-630
- DOI
  10.3389/fimmu.2019.00630
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417
[Journal Article] PD-1 efficiently inhibits T cell activation even in the presence of co-stimulation through CD27 and GITR2019
- Author(s)
  Mizuno Reina、Maruhashi Takumi、Sugiura Daisuke、Shimizu Kenji、Watada Mizuki、Okazaki Il-mi、Okazaki Taku
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 511 Issue: 3 Pages: 491-497
- DOI
  10.1016/j.bbrc.2019.02.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417
[Journal Article] Glucocorticoids potentiate the inhibitory capacity of programmed cell death 1 by up-regulating its expression on T cells2019
- Author(s)
  Maeda Natsumi、Maruhashi Takumi、Sugiura Daisuke、Shimizu Kenji、Okazaki Il-mi、Okazaki Taku
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 52 Pages: 19896-19906
- DOI
  10.1074/jbc.ra119.010379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029
[Journal Article] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura Daisuke、Maruhashi Takumi、Okazaki Il-mi、Shimizu Kenji、Maeda Takeo K.、Takemoto Tatsuya、Okazaki Taku
- Journal Title
  
  Science
  
  Volume: 364 Issue: 6440 Pages: 558-566
- DOI
  10.1126/science.aav7062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03607, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-18KT0024, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029
[Journal Article] PD-1 aborts the activation trajectory of autoreactive CD8+ T cells to prohibit their acquisition of effector functions2019
- Author(s)
  Okamura Hikari、Okazaki Il-mi、Shimizu Kenji、Maruhashi Takumi、Sugiura Daisuke、Mizuno Reina、Okazaki Taku
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 105 Pages: 102296-102296
- DOI
  10.1016/j.jaut.2019.06.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-18K19453, KAKENHI-PROJECT-19K16694, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029
[Journal Article] Stimulatory and Inhibitory Co-signals in Autoimmunity2019
- Author(s)
  Okazaki Taku、Okazaki Il-mi
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 1189 Pages: 213-232
- DOI
  10.1007/978-981-32-9717-3_8
- ISBN
  9789813297166, 9789813297173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-18K19453, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029
[Journal Article] LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII2018
- Author(s)
  Maruhashi Takumi、Okazaki Il-mi、Sugiura Daisuke、Takahashi Suzuka、Maeda Takeo K.、Shimizu Kenji、Okazaki Taku
- Journal Title
  
  Nature Immunology
  
  Volume: 19 Issue: 12 Pages: 1415-1426
- DOI
  10.1038/s41590-018-0217-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19453, KAKENHI-PLANNED-18H05417
[Journal Article] 免疫寛容を標的とした抗体医薬によるがん免疫療法2018
- Author(s)
  岡崎拓、岡崎一美
- Journal Title
  
  実験医学
  
  Volume: 36 Pages: 1836-1840
- Data Source
  KAKENHI-PROJECT-18K19453
[Journal Article] 抑制性免疫補助受容体を標的としたがん免疫療法の基礎研究2016
- Author(s)
  岡崎　拓、岡崎一美
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 Pages: 15861-15864
- Data Source
  KAKENHI-PROJECT-15K19132
[Journal Article] Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation.2011
- Author(s)
  Okazaki IM, Okawa K, Kobayashi M, Yoshikawa K, Kawamoto S, Nagaoka H, Shinkura R, Kitawaki Y, Taniguchi H, Natsume T, Iemura S, Honjo T.
- Journal Title
  
  Proc Natl Acad Sci U S A. 108(19)
  
  Pages: 7920-7925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790473
[Journal Article] PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice.2011
- Author(s)
  Okazaki T, et al.
- Journal Title
  
  J.Exp.Med.
  
  Volume: 208 Pages: 395-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790473
[Journal Article] PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice.2011
- Author(s)
  Okazaki T, Okazaki IM, Wang J, Sugiura D, Nakaki F, Yoshida T, Kato Y, Fagarasan S, Muramatsu M, Eto T, Hioki K, Honjo T.
- Journal Title
  
  J Exp Med. 208(2)
  
  Pages: 395-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790473
[Journal Article] PD-1 deficiency results in the development of fatal myocarditis in MRL mice.2010
- Author(s)
  Wang J, Okazaki IM, Yoshida T, Chikuma S, Kato Y, Nakaki F, Hiai H, Honjo T, Okazaki T.
- Journal Title
  
  Int.Immunol. 22(6)
  
  Pages: 443-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790473
[Journal Article] Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobilin genes.2009
- Author(s)
  Sabouri, Z., Okazaki, I., Shinkura, R., Begum, N.A., Nagaoka, H., Tsuchimoto, D., Nakabeppu, Y., Honjo, T.
- Journal Title
  
  Int.Immunol. 21
  
  Pages: 947-955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.2009
- Author(s)
  Kobayashi, M., Aida, M., Nagaoka, H., Begum, N.A., Kitawaki, Y., Nakata, M., Stanlie, A., Doi, T., Kato, L., Okazaki, I., Shinkura R., Muramatsu, M., Kinoshita, K., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 22375-22380
- NAID
  120001749564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes.2009
- Author(s)
  Sabouri Z, Okazaki IM, Shinkura R, Begum N, Nagaoka H, Tsuchimoto D, Nakabeppu Y, Honjo T.
- Journal Title
  
  Int Immunol. 21(8)
  
  Pages: 947-955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790473
[Journal Article] AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.2009
- Author(s)
  Kobayashi M, Aida M, Nagaoka H, Begum NA, Kitawaki Y, Nakata M, Stanlie A, Doi T, Kato L, Okazaki IM, Shinkura R, Muramatsu M, Kinoshita K, Honjo T.
- Journal Title
  
  Proc Natl Acad Sci U S A. 106(52)
  
  Pages: 22375-22380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790473
[Journal Article] Role of AID in tumorigenesis.2007
- Author(s)
  Okazaki, I.et al.
- Journal Title
  
  Advances in Immunology (in press)
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.2007
- Author(s)
  Matsumoto, Y., Marusawa, H., Kinoshita, K., Endo, Y., Kou, T., Morisawa, T., Azuma, T., Okazaki, I., Honjo, T., Chiba, T.
- Journal Title
  
  Nature Medicine 13
  
  Pages: 470-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] Role of AID in tumorigenesis.2007
- Author(s)
  Okazaki, I., Kotani, A., Honjo, T.
- Journal Title
  
  Adv.Immunol. 94
  
  Pages: 245-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] Rejuvenating exhausted T cells during chronic viral infection.2006
- Author(s)
  Okazaki, T.et al.
- Journal Title
  
  Cell 124
  
  Pages: 459-461
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] PD-1 / PD-L pathway in immunological tolerance.2006
- Author(s)
  Okazaki, T.et al.
- Journal Title
  
  Trends Immunol. 27
  
  Pages: 195-201
- Data Source
  KAKENHI-PROJECT-17002015
[Journal Article] A histone chaperon Spt6 is required for class switch recombination but not somatic hypermutation
- Author(s)
  Il-mi Okazaki, et al.
- Journal Title
  
  PNAS
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002015
[Presentation] PD-1 elicitation by the dissociation of cis-PD-L1/CD80 duplex inhibits T cell activation and alleviates autoimmunity.2021
- Author(s)
  Daisuke Sugiura, Il-mi Okazaki, Takumi Maruhashi, Kenji Shimizu, Reiko Arakaki, Naozumi Ishimaru, Taku Okazaki
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] PD-1 preferentially inhibits the activation of low affinity T cells.2021
- Author(s)
  Kenji Shimizu, Daisuke Sugiura, Il-mi Okazaki, Takumi Maruhashi, Taku Okazaki
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Regulatory mechanisms of T cell activation by immuno-inhibitory co-receptors.2021
- Author(s)
  Taku Okazaki, Kenji Shimizu, Takumi Maruhashi, Daisuke Sugiura, Il-mi Okazaki
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Regulatory mechanisms of T cell activation by immuno-inhibitory co-receptors2021
- Author(s)
  Taku Okazaki, Daisuke Sugiura, Takumi Maruhashi, Kenji Shimizu, Il-mi Okazaki
- Organizer
  FIMSA2021, Federation of Immunological Societies of Asia-Oceania
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] LAG-3 engagement with stable pMHCII is essential for the exertion of its inhibitory function.2021
- Author(s)
  Takumi Maruhashi, Daisuke Sugiura, Il-mi Okazaki, Kenji Shimizu, Taku Okazaki
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] シスPD-L1/CD80結合がT細胞活性化段階におけるPD-1の抑制機能を制限する2020
- Author(s)
  杉浦大祐, 丸橋拓海, 岡崎一美, 清水謙次, 岡崎　拓
- Organizer
  第7回JCRベーシックリサーチカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Regulatory mechanisms of T cell activation by immuno-inhibitory co-receptors.2020
- Author(s)
  Taku Okazaki, Kenji Shimizu, Daisuke Sugiura, Takumi Maruhashi, Il-mi Okazaki
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Binding properties between LAG-3 and two potential ligands, stable pMHCII and FGL12019
- Author(s)
  Maruhashi T, Ikubo J, Sugiura D, Okazaki IM, Okazaki T.
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII2019
- Author(s)
  Maruhashi T, Okazaki IM, Sugiura D, Takahashi S, Maeda TK, Shimizu K, Okazaki T
- Organizer
  The 14th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function for optimal T cell responses2019
- Author(s)
  Okazaki T, Sugiura D, Maruhashi T, Shimizu K, Okazaki IM.
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] T細胞の抗原刺激による遺伝子発現変動にPD-1が与える影響の網羅的解析2019
- Author(s)
  清水謙次, 杉浦大祐, 岡崎一美, 丸橋拓海, 岡崎　拓
- Organizer
  第18回四国免疫フォーラム
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] シスPD-L1/CD80結合がT細胞活性化段階におけるPD-1の抑制機能を制限する2019
- Author(s)
  杉浦大祐,　丸橋拓海, 岡崎一美, 清水謙次, 竹本龍也, 岡崎　拓
- Organizer
  第18回四国免疫フォーラム
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura D, Maruhashi T, Okazaki IM, Shimizu K, Maeda TK, Takemoto T, Okazaki T
- Organizer
  The RIKEN-IMS International Symposium on Immunology 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura D, Maruhashi T, Shimizu K, Okazaki IM, Okazaki T.
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] シンギュラリティ生物学による自己免疫疾患制御機構の解明2019
- Author(s)
  岡崎　拓, 岡村陽香里, 清水謙次, 丸橋拓海, 杉浦大祐, 岡崎一美
- Organizer
  Joint Annual Meeting of the 71st Japan Society for Cell Biology and the 19th Protein Science Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] PD-1 imposes qualitative control of cellular transcriptomes in response to T cell activation2019
- Author(s)
  Shimizu K, Sugiura D, Okazaki IM, Maruhashi T, Takegami Y, Cheng C, Ozaki S, Okazaki T
- Organizer
  The 42nd Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function for optimal T cell activation2019
- Author(s)
  Okazaki T, Sugiura D, Maruhashi T, Shimizu K, Okazaki IM.
- Organizer
  2019 International Symposium of Korean Autoimmunity - Synovitis Study Group
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] シンギュラリティ生物学による自己免疫疾患制御機構の解明2019
- Author(s)
  岡崎　拓, 岡村陽香里, 清水謙次, 丸橋拓海, 杉浦大祐, 岡崎一美
- Organizer
  Joint Annual Meeting of the 71st Japan Society for Cell Biology and the 19th Protein Science Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Okazaki T, Sugiura D, Maruhashi T, Shimizu K, Okazaki IM.
- Organizer
  7th Annual Meeting of the International Cytokine and Interferon Society (Cytokines 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] 抑制性免疫補助受容体によるがん免疫と自己免疫の制御2019
- Author(s)
  岡崎拓, 丸橋拓海, 杉浦大祐, 清水謙次, 岡崎一美
- Organizer
  The 23rd Annual Meeting of Japanese Association of Cancer Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] Restriction of PD-1 function for optimal T cell responses2019
- Author(s)
  Okazaki T, Sugiura D, Maruhashi T, Shimizu K, Okazaki IM
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] 抑制性免疫補助受容体PD-1の機能制御機構2019
- Author(s)
  岡崎拓, 杉浦大祐, 丸橋拓海, 清水謙次, 岡崎一美
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] 抑制性免疫補助受容体によるがん免疫と自己免疫の制御2019
- Author(s)
  岡崎拓, 丸橋拓海, 杉浦大祐, 清水謙次, 岡崎一美
- Organizer
  The 23rd Annual Meeting of Japanese Association of Cancer Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura D, Maruhashi T, Okazaki IM, Shimizu K, Maeda TK, Takemoto T, Okazaki T.
- Organizer
  The RIKEN-IMS International Symposium on Immunology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura D, Maruhashi T, Shimizu K, Okazaki IM, Okazaki T
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Binding properties between LAG-3 and two potential ligands, stable pMHCII and FGL12019
- Author(s)
  Maruhashi T, Ikubo J, Sugiura D, Okazaki IM, Okazaki T
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII2019
- Author(s)
  Maruhashi T, Okazaki IM, Sugiura D, Takahashi S, Maeda TK, Shimizu K, Okazaki T
- Organizer
  The 14th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Okazaki T, Sugiura D, Maruhashi T, Shimizu K, Okazaki IM
- Organizer
  7th Annual Meeting of the International Cytokine and Interferon Society (Cytokines 2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] T細胞の抗原刺激による遺伝子発現変動にPD-1が与える影響の網羅的解析2019
- Author(s)
  清水謙次, 杉浦大祐, 岡崎一美, 丸橋拓海, 岡崎　拓
- Organizer
  第18回四国免疫フォーラム
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] Restriction of PD-1 function for optimal T cell activation2019
- Author(s)
  Okazaki T, Sugiura D, Maruhashi T, Shimizu K, Okazaki IM
- Organizer
  2019 International Symposium of Korean Autoimmunity - Synovitis Study Group
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura D, Maruhashi T, Okazaki IM, Shimizu K, Maeda TK, Takemoto T, Okazaki T
- Organizer
  The 14th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] PD-1 imposes qualitative control of cellular transcriptomes in response to T cell activation2019
- Author(s)
  Shimizu K, Sugiura D, Okazaki IM, Maruhashi T, Takegami Y, Cheng C, Ozaki S, Okazaki T.
- Organizer
  The 42nd Annual Meeting of the Molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] 抑制性免疫補助受容体PD-1の機能制御機構2019
- Author(s)
  岡崎拓, 杉浦大祐, 丸橋拓海, 清水謙次, 岡崎一美
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PROJECT-19H03423
[Presentation] Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses2019
- Author(s)
  Sugiura D, Maruhashi T, Okazaki IM, Shimizu K, Maeda TK, Takemoto T, Okazaki T.
- Organizer
  The 14th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] シスPD-L1/CD80結合がT細胞活性化段階におけるPD-1の抑制機能を制限する2019
- Author(s)
  杉浦大祐,　丸橋拓海, 岡崎一美, 清水謙次, 竹本龍也, 岡崎　拓
- Organizer
  第18回四国免疫フォーラム
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] PD-1 primarily targets TCR-signal in the inhibition of functional T cell activation2018
- Author(s)
  Reina Mizuno, Daisuke Sugiura, Kenji Shimizu, Takumi Maruhashi, Il-mi Okazaki, Taku Okazaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] Single-cell analysis of autoreactive T cells under the control of PD-12018
- Author(s)
  Hikari Okamura, Il-mi Okazaki, Kenji Shimizu, Takumi Maruhashi, Daisuke Sugiura, Mizuno Reina, Taku Okazaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] LAG-3 preferentially inhibits activation of CD4 T cells recognizing stable pMHCII by its conformation-dependent recognition of MHCII2018
- Author(s)
  Takumi Maruhashi, Il-mi Okazaki, Daisuke Sugiura, Kenji Shimizu, Taku Okazaki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] PD-1によるT細胞機能制御における標的分子の解析2018
- Author(s)
  水野玲奈, 杉浦大祐, 清水謙次, 丸橋拓海, 綿田水月, 岡崎一美, 岡崎　拓
- Organizer
  第17回四国免疫フォーラム
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] LAG-3 regulates immunodominance and autoimmunity by its conformation-dependent recognition of MHCII2018
- Author(s)
  Taku Okazaki, Takumi Maruhashi, Il-mi Okazaki, Daisuke Sugiura, Kenji Shimizu
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19453
[Presentation] Glucocorticoids augment the expression and inhibitory function of PD-12017
- Author(s)
  Maeda N, Maruhashi T, Shimizu K, Okazaki IM, Okazaki T
- Organizer
  The 11th International Symposium of the institute network "Frontiers in Biomedical Sciences"
- Place of Presentation
  徳島大学（徳島県・徳島市）
- Year and Date
  2017-01-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Characterization of target genes of inhibitory co-receptor PD-1 by CAGE2017
- Author(s)
  Shimizu K, Sugiura D, Maruhashi T, Okazaki IM, Okazaki T
- Organizer
  The 11th International Symposium of the institute network "Frontiers in Biomedical Sciences"
- Place of Presentation
  徳島大学（徳島県・徳島市）
- Year and Date
  2017-01-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Context-dependent inhibition of antigen-specific T cell activation by LAG-32016
- Author(s)
  Maruhashi T, Okazaki IM, Sugiura D, Okazaki T
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Phenotypic characterization of LAG-3 expressing cells2016
- Author(s)
  Okazaki IM, Okazaki T
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Characterization of target genes of inhibitory co-receptor PD-1 by CAGE2016
- Author(s)
  SHIMIZU Kenji, SUGIURA Daisuke, MARUHASHI Takumi, OKAZAKI Il-mi, OKAZAKI Taku
- Organizer
  The 45th annual meeting of the JSI
- Place of Presentation
  沖縄コンベンションセンター（沖縄県・宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Inhibition of T cell activation by human LAG-32016
- Author(s)
  Kajihara T, Sugiura D, Maruhashi T, Okazaki IM, Okazaki T
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Establishment and maintenance of immune tolerance by immuno-inhibitory receptors2016
- Author(s)
  Maruhashi T, Okazaki IM, Sugiura D, Okazaki T
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] マイノリティ細胞の同定と解析による自己およびがんに対する免疫制御機構の解明2016
- Author(s)
  岡崎一美、清水謙次、岡崎　拓
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Characterization of target genes of inhibitory co-receptor PD-1 by CAGE2016
- Author(s)
  Shimizu K, Sugiura D, Maruhashi T, Okazaki IM, Okazaki T
- Organizer
  The 26th Hot Spring Harbor International Symposium
- Place of Presentation
  九州大学（福岡県・福岡市）
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Glucocorticoids augment the expression and inhibitory function of PD-12016
- Author(s)
  MAEDA Natsumi, MARUHASHI Takumi, SHIMIZU Kenji, OKAZAKI Il-mi, OKAZAKI Taku
- Organizer
  The 45th annual meeting of the JSI
- Place of Presentation
  沖縄コンベンションセンター（沖縄県・宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Comparison of human and mouse LAG-3.2015
- Author(s)
  KAJIHARA Takeo, SUGIURA Daisuke, MIZUNO Reina, RANAWAKAGE Chamila Deshani, MAEDA Natsumi, SHIMIZU Kenji, OKAZAKi Il-mi, OKAZAKI Taku
- Organizer
  The 44th annual meeting of the JSI
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] The strength of inhibition by LAG-3 depends on properties of APCs.2015
- Author(s)
  MARUHASHI Takumi, OKAZAKI Il-mi, SUGIURA Daisuke, KAJIHARA Takeo, OKAZAKI Taku
- Organizer
  The 44th annual meeting of the JSI
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19132
[Presentation] Aida, a newly established animal model of autoimmunity.2010
- Author(s)
  Okazaki T, et al.
- Organizer
  2010年日本免疫学会シンポジウム
- Place of Presentation
  一橋記念講堂(東京都)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Identification of the causal gene of aida mouse, a newly established animal model of autoimmunity.2010
- Author(s)
  Okazaki T, et al.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際展示場(兵庫県)
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Identification of QTLs that modify peripheral neuropathy in NOD.H2b-PD-1KO mice.2010
- Author(s)
  Okazaki IM, Jiang F, Honjo T, Okazaki T.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] a newly established animal model of autoimmunity.2010
- Author(s)
  Okazaki T, Okazaki IM, Sugiura D.Aida
- Organizer
  2010年日本免疫学会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] PD-1 deficiency results in the development of fatal myocarditis in MRL mice.2010
- Author(s)
  岡崎拓, 他
- Organizer
  第9回四国免疫フォーラム
- Place of Presentation
  愛媛大学(愛媛県)
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Identification of the causal gene of aida mouse, a newly established animal model of autoimmunity.2010
- Author(s)
  Okazaki T, Sugiura D, Okazaki IM, Honjo T.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Requirement of isotype-switched and somatically mutated autoantibodies for the development of autoimmune diseases in BALB/c-PD-1KO mice.2010
- Author(s)
  Okazaki T, Sugiura D, Okazaki IM, Honjo T.
- Organizer
  The 4th International Conference on B cells and Autoimmunity
- Place of Presentation
  奈良
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Identification of QTLs that modify peripheral neuropathy in NOD.H2b-PD-1KO mice.2010
- Author(s)
  Okazaki IM, et al.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際展示場(兵庫県)
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] PD-1 deficiency results in the development of fatal myocarditis in MRL mice.2010
- Author(s)
  岡崎拓、岡崎一美
- Organizer
  第9回四国免疫フォーラム
- Place of Presentation
  松山
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Requirement of isotype-switched and somatically mutated autoantibodies for the development of autoimmune diseases in BALB/c-PD-1KO mice.2010
- Author(s)
  Okazaki T, et al.
- Organizer
  The 4th International Conference on B cells and Autoimmunity
- Place of Presentation
  奈良ロイヤルホテル(奈良県)
- Year and Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Involvement of Topoisomerase I in class switch recombination.2009
- Author(s)
  Kobayashi M, Aida M, Nagaoka H, Begum NA, Kitawaki Y, Nakata M, Stanlie A, Doi T, Kato L, Okazaki IM, Shinkura R, Muramatsu M, Kinoshita K, Honjo T.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] 自己免疫性胃炎モデルマウスにおける自己抗原同定の試み2009
- Author(s)
  梶原武雄, 杉浦大祐, 岡崎一美, 岡崎拓
- Organizer
  第33回徳島県医学検査学会
- Place of Presentation
  徳島
- Year and Date
  2009-12-13
- Data Source
  KAKENHI-PROJECT-21790473
[Presentation] Involvement of Topoisomerase I in class switch recombination of Immunoglobulin genes.2009
- Author(s)
  Kobayashi M, Aida M, Doi T, Nagaoka H, Kitawaki Y, Nakata M, Kato L, Stanlie A, Begum NA, Okazaki IM, Shinkura R, Muramatsu M, Kinoshita K, Honjo T.
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21790473

1. SHINKURA Reiko (50362471)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. BEGUM Nasim (80362507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. HONJO Tasuku (80090504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. NISHIKORI Momoko (60378635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAGAOKA Hitoshi (20270647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KOBAYASHI Maki (20400690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. DOI Tomomitsu (70437218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. ARAKAKI Rieko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. TAKEMOTO Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 新蔵礼子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 岡崎拓

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Okazaki IlMi 岡崎 一美

OKAZAKI Il-mi 岡崎 一美

CHON Il-Mi 鄭 一美

Research Projects

Research Products

Co-Researchers

Regulatory mechanism of allergic disease development by inhibitory co-receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Elucidating molecular mechanisms of the regulation of immunodominancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic analysis of autoimmune myocarditisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanisms of autoimmunity by LAG-3 expressing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of PD-1 and AIDA in inflammation-induced tumorigenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AID-dependent genetic alteration mechanism to generate antigen-specific antibodies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Role of AID in tumorigenesis.,Vol.942007

Author(s)

Publisher

Data Source

[Journal Article] PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Binding of LAG-3 to stable peptide-MHC class II limits T?cell function and suppresses autoimmunity and anti-cancer immunity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T-cell-intrinsic and -extrinsic regulation of PD-1 function2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PD-1 preferentially inhibits the activation of low-affinity T cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LAG-3: from molecular functions to clinical applications2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation2019

Author(s)

Journal Title

DOI

Okazaki IlMi 岡崎一美

OKAZAKI Il-mi 岡崎一美

CHON Il-Mi 鄭一美