YAMASHITA Yasuhisa 山下泰尚

… Alternative Names

Researcher Number	50452545
Other IDs
Affiliation (Current)	2021: 県立広島大学, 生命環境学部, 准教授 2021: 県立広島大学, 生物資源科学部, 准教授
Affiliation (based on the past Project Information) *help	2019: 県立広島大学, 生命環境学部, 准教授 2010 – 2016: 県立広島大学, 生命環境学部, 准教授 2007 – 2009: Tottori University, 農学部, 助教
Review Section/Research Field	Principal Investigator Applied animal science / Animal production science / Basic Section 42010:Animal production science-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 排卵 / 卵胞発育 / 卵成熟 / 卵子成熟 / 卵丘細胞 / 体外成熟培養 / 卵子 / 産業動物 / プロジェステロン / コレステロール生合成経路 … More Except Principal Investigator 卵巣 / 排卵 / 卵成熟 / 減数分裂 / IVM / 成長因子 / シグナル伝達 / 遺伝子発現 / 卵丘細胞 / neuregulin 1 / sphingogosine 1 kinase / 卵子 / cAMP Less

Analysis and application of follicular somatic cell-dependent oocyte metabolic regulation and epigenome regulation controled by iron during follicular development.Principal InvestigatorOngoing
- Principal Investigator
  
  山下泰尚
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Prefectural University of Hiroshima
Exploration of oocyte maturation inducing factor by analysis of time-specific regulation of ADAM17 substrate specificity during follicular development and ovulation process.Principal Investigator
- Principal Investigator
  
  Yamashita Yasuhisa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Prefectural University of Hiroshima
The exploitation of IVG system based on selection of dominant follicle dependent on protesterone deactivation enzyme.Principal Investigator
- Principal Investigator
  
  YAMASHITA Yasuhisa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied animal science
- Research Institution
  Prefectural University of Hiroshima
The study for development of in vitro culture system of mammalian oocyte by global analysis of cumulus cell-stimulating substrate during ovulating processPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Yasuhisa
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied animal science
- Research Institution
  Prefectural University of Hiroshima
卵丘細胞のERKとPKB系に着目した哺乳動物卵子減数分裂再開制御因子の探索
- Principal Investigator
  
  島田昌之
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
The exploitation of novel in vitro maturation system of mammalian cumulus-oocyte complex that enhances SREBP gene in cumulus cellsPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Yasuhisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Applied animal science
- Research Institution
  Tottori University

All 2019 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 哺乳動物卵子の成熟と排卵のメカニズム（日本卵子学会胚培養士テキスト）2016
- Author(s)
  島田昌之、星野由美、山下泰尚
- Total Pages
  8
- Publisher
  日本卵子学会
- Data Source
  KAKENHI-PROJECT-26450381
[Book] 生殖医学研究の最前線（排卵期における顆粒膜細胞分泌因子の発現・分泌制御機構とその生理的役割）2014
- Author(s)
  島田昌之、山下泰尚
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24780271
[Book] 生体の科学(64(5),ISSN 1883-5503) 卵の成熟におけるEGF受容体の活性化と活性化因子2013
- Author(s)
  島田昌之、山下泰尚
- Data Source
  KAKENHI-PROJECT-24780271
[Book] 生体の科学（卵の成熟におけるEGF受容体の活性化と活性化因子）2013
- Author(s)
  島田昌之、山下泰尚
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24780271
[Book] 卵子学:卵子成熟時および初期胚発達期における代謝機構2011
- Author(s)
  島田昌之、山下泰尚
- Total Pages
  11
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-22780251
[Book] 卵子学2011
- Author(s)
  島田昌之, 山下泰尚
- Publisher
  京都大学出版会
- Data Source
  KAKENHI-PROJECT-22780251
[Book] 卵子学:卵子成熟時および初期胚発達期における代謝機構2011
- Author(s)
  島田昌之, 山下泰尚
- Total Pages
  1195
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-22780251
[Book] 卵子・初期胚の代謝機構2009
- Author(s)
  山下泰尚、島田昌之
- Publisher
  卵子学(印刷中)
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] Developmental of artificial insemination technique in pig production based on the evidence of physiology and molecular biology in reproductive organs2016
- Author(s)
  Shimada M, Okazaki T, Yamashita Y.
- Journal Title
  
  Agri-Bioscience Monographs
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26450381
[Journal Article] The novel pig in vitro maturation system to improve developmental competence of oocytes derived from atretic non-vascularized follicle.2016
- Author(s)
  Okamoto A, Ikeda M, Kaneko A, Kishida C, Shimada M, Yamashita Y
- Journal Title
  
  Biology of Reproduction
  
  Volume: 95 Pages: 1-16
- DOI
  10.1095/biolreprod.116.138982
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05017, KAKENHI-PROJECT-26450381
[Journal Article] Development of artificial insemination technique in pig production based on the evidence of physiology and molecular biology in reproductive organs.2016
- Author(s)
  Shimada M, Yamashita Y, Okazaki T.
- Journal Title
  
  Agri-Biosciene Monographs
  
  Volume: 6 Pages: 59-83
- DOI
  10.5047/agbm.2016.00602.0059
- NAID
  40021125070
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450381
[Journal Article] Protein kinase C (PKC) increases TACE/ADAM17 enzyme　activity in porcine ovarian somatic cells, which is essential for granulosa cell luteinization and oocyte maturation.2014
- Author(s)
  Yamashita Y, Okamoto M, Ikeda M, Okamoto A, Sakai M, Gunji Y, Nishimura R, Hishinuma M, Shimada M
- Journal Title
  
  Endocrinology
  
  Volume: 155 Pages: 1080-1090
- DOI
  10.1210/en.2013-1655
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24688028, KAKENHI-PROJECT-24780271, KAKENHI-PUBLICLY-25132708
[Journal Article] Protein kinase C (PKC) increases TACE/ADAM17 enzyme activity in porcine ovarian somatic cells, which is essential for granulosa cell luteinization and oocyte maturation.2014
- Author(s)
  Yamashita Y, Okamoto M, Ikeda M, Okamoto A, Sakai M, Gunji Y, Nishimura R, Hishinuma M, Shimada M.
- Journal Title
  
  Endocrinology
  
  Volume: 155(3) Pages: 1080-1090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450381
[Journal Article] The Release of EGF Domain from EGF-like Factors by a Specific Cleavage Enzyme Activates the EGFR-MAPK3/1 Pathway in Both Granulosa Cells and Cumulus Cells During the Ovulation Process2012
- Author(s)
  Yamashita & Shimada
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: 58 Issue: 5 Pages: 510-514
- DOI
  10.1262/jrd.2012-056
- NAID
  10031123293
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24688028, KAKENHI-PROJECT-24780271
[Journal Article] The key signaling cascades in granulosa cells during follicular development and ovulation process2011
- Author(s)
  M.Shimada, Y.Yamashita
- Journal Title
  
  Journal of Mammalina Ova Research
  
  Volume: 28 Pages: 25-33
- NAID
  10028123927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Effect of butylated hydroxytikuene on dog sperm longevity in chilling storage and cryopreservation2011
- Author(s)
  Sahashi Y, Otsuki T, Higaki S, Nagano M, Yamashita Y, Hishinuma M
- Journal Title
  
  Journal of Veterinary Medicine Science
  
  Volume: 73 Pages: 1355-1357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Effect of Butylated Hydroxytoluene on Dog Sperm Longevity in Chilling Storage and Cryopreservation2011
- Author(s)
  Sahashi Y, Otsuki T, Higaki S, Nagano M, Yamashita Y, Hishinuma M
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 73 Issue: 7 Pages: 895-899
- DOI
  10.1292/jvms.10-0460
- NAID
  130000676902
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] The key signaling cascades in granulosa cells during follicular development and ovulation process2011
- Author(s)
  Shimada M, Yamashita Y
- Journal Title
  
  Journal of Mammalian Ova Research
  
  Volume: 28 Pages: 25-31
- NAID
  10028123927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Positive feedback loop between prostaglandin E2 and EGF-like factors is essential of the sustainable activation of MAPK3/1 in cumulus cells during in vitro maturation of porcine cumulus-oocyte complexes2011
- Author(s)
  Yamashita Y, Okamoto M, Kawashima I, Nishmura R, Gunji Y, Hishinuma M, Shimada M
- Journal Title
  
  Biology of Reproduction
  
  Volume: 85 Pages: 1073-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Effect of butylated hydrooxytoluene on dog sperm longevity in chilling storage and cryopreservation2011
- Author(s)
  Y.Sahashi, T.Otsuki, S.Higaki, M.Nagano, Y.Yamashita, M.Hishinuma
- Journal Title
  
  The Journal of Veterinaly Medical Science
  
  Volume: 73 Pages: 895-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Positive feedback loop between prostagrandin E2 and EGF-like factors is essential for sustainable activation of MAPK3/1 in cumulus cells during in vitro maturation of porcine cumulus oocyte complexes2011
- Author(s)
  Yamashita, et al
- Journal Title
  
  Biology of Reproduction
  
  Volume: 85 Pages: 1073-1082
- DOI
  10.1095/biolreprod.110.090092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688019, KAKENHI-PROJECT-22780251
[Journal Article] The positive feedback loop between prostagrandin E2 (PGE2) and EGF-like factors is essential for the sustainable activation of ERK1/2 in cumulus cells during in vitro maturation of porcine cumulus-oocyte complexes (COCs)2011
- Author(s)
  Y.Yamashita, M.Okamoto, I.Kawashima, T.Okazaki, R, Nishimura, Y.Gunji, M.Hishinuma, M.Shimada
- Journal Title
  
  Biology of Reproduction
  
  Volume: 85 Pages: 1073-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Cryopreservation of microencapsulated canine sperm2011
- Author(s)
  Sha S, Otsuki T, Fujiwara C, Yamamoto N, Yamashita Y, Higaki S, Hishinuma M
- Journal Title
  
  Theriogenology
  
  Volume: 75 Pages: 679-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Progesterone is essential for maintenance of Tace/Adam17 mRNA expression, but not EGF-like factor in cumulus cells, which enhances the EGF receptor signaling pathway during in vitro maturation of porcine COCs2010
- Author(s)
  Yamashita Y, Kawashima I, Gunji Y, Nishimura R, Hishinuma M, Shimada M
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: 56 Pages: 315-323
- NAID
  10026434172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Microencapsulation of canine sperm and its preservation at 4 degree C2010
- Author(s)
  Shah S, Nagano M, Yamashita Y, Hishinuma M
- Journal Title
  
  Theriogenology
  
  Volume: 73 Pages: 560-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Progesterone is essential for mailtenance of Tace/Adam 17 mRNA expression, but not EGF-like factor, in cumulus cells, which enhances EGF receptor signaling pathway during in vitro maturation of prcine COCs2010
- Author(s)
  Yamashita Y
- Journal Title
  
  J Reprod Dev (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028014
[Journal Article] Progesterone is essential for maintenance of Tace/Adam17 mRNA expression, but not EGF-like factor, in cumulus cells, which enhances EGF receptor signaling pathway during in vitro maturation of porcine COCs2010
- Author(s)
  Yamashita Y.
- Journal Title
  
  J Reprod Dev
  
  Volume: 56(3) Pages: 315-323
- NAID
  10026434172
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028014
[Journal Article] Progesterone is essential for maintenance of Tace/Adam17 mRNA expression, but not EGF-like factor, in cumulus cells, which enhances EGF receptor signaling pathway during in vitro maturation of porcine COCs2010
- Author(s)
  Y.Yamashita, I.Kawashima, Y.Gunji, M.Hishinuma, M.Shimada
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: 56 Pages: 315-323
- NAID
  10026434172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Journal Article] Activation of PKA, p38MAPK and ERK1/2 by gonadotropils in cumulus cells is critical for induction of EGF-like factor and TACE/ADAM 17 gene expression during in vitro maturation of porcine COCs2009
- Author(s)
  Yamashita Y
- Journal Title
  
  J Ovarian Res 2
  
  Pages: 20-20
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028014
[Journal Article] Sequential exposure of porcine cumulus cells to FSH and/or LH is critical for appropriate expression of steroidogenic and ovulation-related genes that impact oocyte maturation in vivo and in vitro2008
- Author(s)
  Ikkou Kawashima、Tetsuji Okazaki、Noritaka Noma、Masahide Nishibori、Yasuhisa Yamashita、Masayuki Shimada
- Journal Title
  
  Reproduction vol.136
  
  Pages: 9-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] Sequential exposure of porcine cumulus cells to FSH and/or LH is critical for appropriate expression of steroido genie and ovulat ion-related genes that impact oocyte maturation in vivo and in vitro2008
- Author(s)
  Ikkou Kawashima, Tetsuji Okazaki, Noritaka Noma, Masahide Nishibori, Yasuhisa Yamashita. Masayuki Shimada
- Journal Title
  
  Reproduction 136
  
  Pages: 9-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] Synaptosomal-associated protein 25 gene expression is hormonally regulated during ovulation and is involved in cytokine/chemokine exocytosis from granulosa cells.2007
- Author(s)
  Shimada M, Yanai Y, Okazaki T, Yamashita Y, Sriraman V, Wilson MC, Richards JS.
- Journal Title
  
  Molecular Endocrinology 21
  
  Pages: 2487-2502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] Hormone-induced expression of tumor necrosis factor alpha-converting enzyme/A disintegrin and metalloprotease-17 impacts prcine cumulus cell oocyte complex expansion and meiotic maturation via ligand activation o the epidermal growth factor receptor2007
- Author(s)
  Yasuhisa Yamashita、Ikkou Kawashima、Yoshinari Yanai、Masahide Nishibori、JoAnne S Richards、Masayuki Shimada
- Journal Title
  
  Endocrinology vol.148
  
  Pages: 6164-6175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] Hormone-induced expression of tumor necrosis factor alpha-converting enzyme/A disintegrin and metalloprotease-17 impacts porcine cumulus cell oocyte complex expansion and meiotic maturation via ligand activation of the epidermal growth factor receptor.2007
- Author(s)
  Yamashita Y, Kawashima I, Yanai Y, Nishibori M, Richards JS, Shimada M.
- Journal Title
  
  Endocrinology 148
  
  Pages: 6164-6175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] 排卵期特異的なEGF like factorの発現機構とその作用
- Author(s)
  下中麻奈美, 山下泰尚, JoAnne S. Richards, 島田昌之
- Journal Title
  
  日本生殖内分泌学会誌 14(印刷中)
- Data Source
  KAKENHI-PROJECT-19880020
[Journal Article] The release of EGF domain from EGF-like factors by specific cleavage enzyme activates EGFR-MAPK3/1 pathway in both granulosa cells and cumulus cells during ovulation process
- Author(s)
  Yamashita Y, Shimada M
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: (in press)
- NAID
  10031123293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] マウス卵巣におけるコレステロー新規合成制御因子の発言とその役割2019
- Author(s)
  中西寛弥，田中里沙，山下泰尚
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-19K06359
[Presentation] 卵胞発育期特異的な卵巣ー肝臓における新規コニュニケーションの存在と意義2019
- Author(s)
  藤内慎梧，川端茜，成田恵菜，山下泰尚
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-19K06359
[Presentation] マウス卵管においてNeurotensin依存的に発現するLipocalin2は精子運動生を亢進する2019
- Author(s)
  岡本麻子，李周蓮，山下泰尚
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-19K06359
[Presentation] 卵丘細胞で発現するNeurotensinのEGFR活性維持を介した卵成熟調節機能2016
- Author(s)
  岡本麻子、島田昌之、山下泰尚
- Organizer
  第20回日本生殖内分泌学会学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] 卵子成熟、排卵海底の顆粒膜細胞および卵丘細胞に発現する神経ペプチド・NeurotensinによるEGF受容体活性維持制御2016
- Author(s)
  山下泰尚
- Organizer
  第57回日本卵子学会
- Place of Presentation
  朱鷺メッセ（新潟市）
- Year and Date
  2016-05-14
- Invited
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] 排卵時の顆粒膜細胞で発現するNeurotensinはADAM17活性を亢進し、卵丘細胞のEGF受容体-ERK1/2系の持続的活性化を誘導する2016
- Author(s)
  岡本麻子、島田昌之、山下泰尚
- Organizer
  第57回日本卵子学会
- Place of Presentation
  朱鷺メッセ（新潟市）
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] Transferrin(TF)-Fe3+により誘導されるブタ卵の減数分裂裁可抑制とその卵の発生に及ぼす影響2016
- Author(s)
  河端茜、堺優俊、清亜咲美、島田昌之、山下泰尚
- Organizer
  第121回日本畜産学会学術集会
- Place of Presentation
  日本獣医生命科学大学
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] プロゲステロン代謝酵素依存的に蓄積するコルチゾールとその卵胞退行への影響2016
- Author(s)
  岡本麻子、金子亜絵理、池田真規、島田昌之、山下泰尚
- Organizer
  第121回日本畜産学会学術集会
- Place of Presentation
  日本獣医生命科学大学
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] 顆粒膜細胞のCYP11B1発現依存的コルチゾール産生が引き起こす卵胞退行メカニズム2015
- Author(s)
  岡本麻子、池田真規、島田昌之、山下泰尚
- Organizer
  第56回日本卵子学会学術集会
- Place of Presentation
  栃木県総合文化センター
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] Transferrin-Fe3+は顆粒層細胞と卵丘細胞の機能性を亢進し、卵胞発育を誘導する2015
- Author(s)
  河端茜、内橋しづき、島田昌之、山下泰尚
- Organizer
  第108回日本繁殖生物学会学術集会
- Place of Presentation
  宮崎大学
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] プロゲステロン代謝抑制が誘導するブタ卵胞部選抜メカニズム2015
- Author(s)
  岡本麻子、金子亜絵理、池田真規、島田昌之、山下泰尚
- Organizer
  第108回日本繁殖生物学会学術集会
- Place of Presentation
  宮崎大学
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] 健常卵胞と退行卵胞における経時的ステロイドホルモン比較解析とそれを応用した退行卵胞由来ブタ卵の新規IVM法の確立2014
- Author(s)
  池田真規、島田昌之,山下泰尚
- Organizer
  第118回日本畜産学会つくば大会
- Place of Presentation
  つくば国際会議場(日本畜産学会優秀発表賞受賞)
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-24780271
[Presentation] 健常卵胞と退行卵胞における経時的ステロイドホルモン比較解析とそれを応用した退行卵胞由来ブタ卵の新規IVM法の確立2014
- Author(s)
  池田真規、島田昌之、山下泰尚
- Organizer
  第118回日本畜産学会
- Place of Presentation
  茨城県つくば市、つくば国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-24780271
[Presentation] 卵胞発育・成熟機構の解明による良好成熟卵を得るIVM法の開発2013
- Author(s)
  山下泰尚、島田昌之
- Organizer
  日本生殖再生医学会
- Place of Presentation
  東京、シェンバッハ・サボー
- Invited
- Data Source
  KAKENHI-PROJECT-24780271
[Presentation] EGF-like factor-ADAM17 networkにより誘導される哺乳動物卵の成熟機構の解析と応用2012
- Author(s)
  山下泰尚、菱沼貢、島田昌之
- Organizer
  日本獣医学会第153回学術集会
- Place of Presentation
  国立感染症研究所
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] EGF-like factor-Adam17 networkにより誘導される哺乳動物卵の成熟機構の解析と応用2012
- Author(s)
  山下泰尚、菱沼貢、島田昌之
- Organizer
  第153回日本獣医学会
- Place of Presentation
  国立感染症研究所
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] EGF-like factor-ADAM17 networkにより誘導される哺乳動物卵の成熟機構の解析と応用2012
- Author(s)
  山下泰尚, 菱沼貢, 島田昌之
- Organizer
  第153回日本獣医学会
- Place of Presentation
  埼玉県
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 犬精子の凍結保存における凍結保存液の浸透圧とグリセリン濃度の検討2011
- Author(s)
  藤村千加, 檜垣彰吾, 郡司庸介, 大月翼, 泉千尋, 岡崎哲司, 島田昌之, 山下泰尚, 菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 卵胞液中ホルモン濃度の経時的変化を模倣した牛卵子体外培養法の開発2011
- Author(s)
  郡司庸介, 武井直樹, 渡邊貴之, 光藤弘俊, 西村亮, 山下泰尚, 檜垣彰吾, 鈴木稔, 菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 哺乳動物卵子の成熟・排卵機構の基礎的解析とその応用2011
- Author(s)
  山下泰尚, 菱沼貢, 島田昌之
- Organizer
  第151回日本獣医学会
- Place of Presentation
  東京都
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 犬精子の凍結保存における凍結保存液の浸透圧とグリセロール濃度の検討2011
- Author(s)
  藤村千加、檜垣彰吾、郡司庸介、大月翼、泉千尋、岡崎哲司、島田昌之、山下泰尚、菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府立大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 牛卵胞および黄体におけるBNIP3の発現2011
- Author(s)
  西村亮, 奥田潔, 郡司庸介, 光藤弘俊, 檜垣彰吾, 山下泰尚, 菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] ブタ顆粒膜細胞において、PKCとc-Src依存的なTACE/ADAM17の活性化が,EGF like factorの分泌を介して顆粒膜細胞の黄体化,卵丘膨化,および卵成熟を促進する2011
- Author(s)
  山下泰尚・岡本美奈子・菱沼貢・島田昌之
- Organizer
  第五十二回日本哺乳動物卵子学会
- Place of Presentation
  国際医療福祉大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 牛卵胞および黄体におけるBNIP3の発現2011
- Author(s)
  西村亮、奥田潔、郡司庸介、光藤弘俊、檜垣彰吾、山下泰尚、菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府立大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 卵胞液中ホルモン濃度の濃度経時的変化と牛卵子体外成熟培養法の開発2011
- Author(s)
  郡司庸介、武井直樹、渡邊貴之、光藤弘俊、西村亮、山下泰尚、檜垣彰吾、鈴木稔、菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府立大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] ブタ顆粒膜細胞において、PKCとc-Src依存的なTACE/ADAM17の活性化が、EGF-like factorの分泌を介して顆粒膜細胞の黄体化、卵丘膨化、および卵成熟を促進する2011
- Author(s)
  山下泰尚、岡本美奈子、菱沼貢、島田昌之
- Organizer
  第52回日本哺乳動物卵子学会
- Place of Presentation
  国際医療福祉大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 牛卵巣における黄体の有無が体外胚の生産に及ぼす影響2011
- Author(s)
  光藤弘俊、郡司庸介、西村亮、山下泰尚、檜垣彰吾、菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府立大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 牛卵巣における黄体の有無が体外胚の生産に及ぼす影響2011
- Author(s)
  光藤弘俊, 郡司庸介, 西村亮, 山下泰尚, 檜垣彰吾, 菱沼貢
- Organizer
  第152回日本獣医学会
- Place of Presentation
  大阪府
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] ブタ顆粒膜細胞において, PKCとc-Src依存的なTACE./ADAM17の活性化が, EGF-like factorの分泌を介して顆粒膜細胞の黄体会,卵丘膨化,および卵成熟を促進する2010
- Author(s)
  山下泰尚, 岡本美奈子, 菱沼貢, 島田昌之
- Organizer
  第52回日本哺乳動物卵子学会
- Place of Presentation
  栃木県
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 鳥取県内に生息する野生ヌートリアの繁殖生理2010
- Author(s)
  伊從留南, 山下泰尚, 檜垣彰吾, 菱沼貢
- Organizer
  第44回鳥取県獣医学会
- Place of Presentation
  鳥取市
- Year and Date
  2010-07-17
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] 卵丘細胞におけるERK1/2の持続的な活性化機構とその卵子成熟に果たす意義2010
- Author(s)
  山下泰尚
- Organizer
  第112回日本畜産学会大会
- Place of Presentation
  東京
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PUBLICLY-21028014
[Presentation] Crypereservation of microencapcelated canine sperm2010
- Author(s)
  Shah S, 大月翼, 藤村千加, 山本直樹, 山下泰尚, 檜垣彰吾, 菱沼貢
- Organizer
  第150回日本獣医学会
- Place of Presentation
  帯広市
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] PGE2は,卵丘細胞のERK1/2を持続的に活性化させ,卵子成熟を誘導する2010
- Author(s)
  山下泰尚, 岡本美奈子, 菱沼貢・島田昌之
- Organizer
  日本繁殖生物学会
- Place of Presentation
  北里大学
- Data Source
  KAKENHI-PROJECT-22780251
[Presentation] PGE2によるERK1/2のポジティブフィードバック機構がブタ卵丘細胞卵子複合体の卵丘細胞の膨潤と卵子成熟に必須である2010
- Author(s)
  山下泰尚
- Organizer
  日本繁殖生物学会
- Place of Presentation
  十和田市
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PUBLICLY-21028014
[Presentation] PKC依存的なADAM17の活性化が卵丘細胞の機能性変化に及ぼす影響2009
- Author(s)
  山下泰尚, 島田昌之
- Organizer
  第4回日本生殖再生医学会
- Place of Presentation
  東京
- Year and Date
  2009-03-15
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PKC依存的なADAM17の活性化が卵子成熟に及ぼす影響2009
- Author(s)
  山下泰尚、島田昌之
- Organizer
  第110回日本畜産学会
- Place of Presentation
  日本大学
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PKC依存的なADAM17の活性化が卵子成熟に果たす役割2009
- Author(s)
  山下泰尚, 島田昌之
- Organizer
  第110回日本畜産学会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] EGF-like factor-TACE/ADAM17系により誘起される卵子成熟機構の解析2008
- Author(s)
  山下泰尚, 水上貴裕, 永野昌史, 菱沼貢, 島田昌之
- Organizer
  第146回日本獣医学会
- Place of Presentation
  宮崎大学
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PGE2およびProgesterone(P4)はADAM17の発現を誘起させ卵丘細胞の膨潤を誘起する2008
- Author(s)
  山下泰尚、JoAnne S. Richards、島田昌之
- Organizer
  第109回日本畜産学会
- Place of Presentation
  常磐大学
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] EGF-like factors-ADAM17 pathwayにより誘起される卵子成熟、排卵機構の解析2008
- Author(s)
  山下泰尚、水上貴裕、川島一公、岡崎哲司、島田昌之
- Organizer
  第3回日本生殖再生医学会
- Place of Presentation
  東京
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] EGF-like factors-TACE/ADAM17 pathwayにより誘起される卵子成熟・排卵機構の解析2008
- Author(s)
  山下泰尚・水上貴裕・川島一公・岡崎哲司・島田昌之
- Organizer
  日本生殖再生医学会
- Place of Presentation
  東京都
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PGE2 and protesterone enhance EGFR activation in porcine cumukus cells via the induction of TACE/ADAM17 expression but not EGF like factors expression during oocyte maturation in vivo and in vitro2008
- Author(s)
  Yasuhisa Yamashita, Tetsuji Okazaki, Ikkou Kawashima, Masayuki Shimada
- Organizer
  Society for the Study of Reproduction, 41st Annual Meeting
- Place of Presentation
  アメリカ合衆国、ハワイ
- Year and Date
  2008-05-29
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PKC依存的なADAM17の活性化が卵丘細胞の機能性変化に及ぼす影響2008
- Author(s)
  山下泰尚、島田昌之
- Organizer
  第14回日本生殖内分泌学会
- Place of Presentation
  鳥取大学
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PKC依存的なADAM17の活性化が卵丘細胞の機能性変化に及ぼす影響2008
- Author(s)
  山下泰尚, 島田昌之
- Organizer
  第14回日本生殖内分泌学会
- Place of Presentation
  東京
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PKC依存的なADAM17の活性化が卵丘細胞の機能性変化に及ぼす影響2008
- Author(s)
  山下泰尚、島田昌之
- Organizer
  第4回日本生殖再生医学会
- Place of Presentation
  東京
- Year and Date
  2008-03-15
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 猫の卵巣周期と胞状卵胞直径が卵子成熟に与える影響2008
- Author(s)
  内倉健造, 永野昌志, 寺野貴之, 山下泰尚, 菱沼貢
- Organizer
  第146回日本獣医学会
- Place of Presentation
  宮崎大学
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 犬および猫精子の運動性とミトコンドリア活性の関係2008
- Author(s)
  山本直樹, 永野昌志, 内倉健造, 山下泰尚, 菱沼貢
- Organizer
  第146回日本獣医学会
- Place of Presentation
  宮崎大学
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] PGE2 and progesterone enhance EGFR activation in porcine cumulus cells via the induction of TACE/ADAM17 expression but not EGF-like factors expression during oocyte maturation in vivo and in vitro2008
- Author(s)
  Yasuhisa Yamashita、Tetsuji Okazaki、Ikkou Kawashima、Masayuki Shimada
- Organizer
  41th Annual meeting of society for the study of reproduction
- Place of Presentation
  Hawaii、USA(407)
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] Sequential exposure of porcine cumulus cells to FSH and LH is critical ofr appropriate expression of steroidogenic and ovulation related genes that impact oocyte maturation in vivo and in vitro2008
- Author(s)
  Masayuki Shimada、Ikkou Kawashima、Tetsuji Okazaki、Yasuhisa Yamashita
- Organizer
  41th Annual meeting of the soxiety for the study of reproduction
- Place of Presentation
  Hawaii、USA(405)
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] EGF-like factor-ADAM17系により誘起される卵丘細胞膨潤機構の解明2008
- Author(s)
  山下泰尚・JS. Richards・島田昌之
- Organizer
  日本畜産学会
- Place of Presentation
  茨城県
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] Sequential exposure of porcine cumulus cells to FSH and LH is critical for appropriate expression of steroidogenic and ovulation-related genes that impact for oocyte maturation in vivo and in vitro.2008
- Author(s)
  Masayuki Shimada, Ikkou Kawashima, Tetsuji Okazaki, Yasuhisa Yamashita
- Organizer
  Society for the Study of Reproduction, 41st Annual Meeting
- Place of Presentation
  アメリカ合衆国、ハワイ
- Year and Date
  2008-05-29
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] EGF-like factor-ADAM17系により誘導される卵子成熟機構の解析2008
- Author(s)
  山下泰尚、水上貴裕、永野昌志、菱沼貢、島田昌之
- Organizer
  第146回日本獣医学会
- Place of Presentation
  宮崎大学
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 卵丘細胞のADAM17発現とそのEGFRシグナル系を介して誘起される卵丘細胞の膨潤に果たす役割2007
- Author(s)
  山下泰尚・西堀正英・JS. Richards・島田昌之
- Organizer
  日本哺乳動物卵子学会
- Place of Presentation
  山梨県
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 犬射出精子の冷蔵および凍結保存におけるButylated hydroxytoluene(BHT)の効果2007
- Author(s)
  佐橋悠、永野昌志、山下泰尚、菱沼貢
- Organizer
  日本獣医学会
- Place of Presentation
  北海道
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] MTT(3[4,5-dimethylthiazolyl]-2,5-diphenyltetrazolium bromide)を用いた犬および猫精子の生存性検査2007
- Author(s)
  永田麻理子、佐橋悠、内倉健造、永野昌志、山下泰尚、菱沼貢
- Organizer
  日本繁殖生物学会
- Place of Presentation
  東京都
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 卵丘細胞におけるADAM17の発現変化とそのEGFRシグナル系を介して誘起される卵丘細胞の膨潤に果たす役割2007
- Author(s)
  山下泰尚、西堀正英、JoAnne S. Richards、島田昌之
- Organizer
  第48回日本哺乳動物卵子学会
- Place of Presentation
  山梨大学
- Year and Date
  2007-05-27
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 異種間体外授精を用いた犬精子の受精能評価法の開発2007
- Author(s)
  佐橋悠、永野昌志、山下泰尚、内倉建造、永田麻理子、菱沼貢
- Organizer
  日本繁殖生物学会
- Place of Presentation
  東京都
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 若齢猫における卵胞発育動態および胞状卵胞内卵子の体外受精に関する研究2007
- Author(s)
  内倉健造、永野昌志、山下泰尚、菱沼貢
- Organizer
  日本獣医学会
- Place of Presentation
  北海道
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19880020
[Presentation] 健常卵胞のステロイドホルモン環境が退行卵胞由来COCのアポトーシスに及ぼす影響
- Author(s)
  池田真規、清亜咲美、門川真諭、島田昌之、山下泰尚
- Organizer
  第107回日本繁殖生物学会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] ブタ卵胞発育時のプロゲステロン代謝酵素・AKR1C1の発現と役割
- Author(s)
  岡本麻子、門川真諭、池田真規、島田昌之、山下泰尚
- Organizer
  第119回日本畜産学会
- Place of Presentation
  宇都宮大学
- Year and Date
  2015-03-27 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] 卵丘細胞におけるNeurotensinのEGF受容体発現上昇作用とそれが卵丘細胞膨潤と卵成熟に果たす役割
- Author(s)
  岡本麻子、成田恵菜、河端茜、島田昌之、山下泰尚
- Organizer
  第107回日本繁殖生物学会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] ブタ卵丘細胞卵複合体(COC)の体外培養時におけるNeurotensin(NTS)の発現とその役割
- Author(s)
  永村優、岡本麻子、島田昌之、山下泰尚
- Organizer
  第107回日本繁殖生物学会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-26450381
[Presentation] Neurotensinは、排卵時にヒアルロン酸産生を促し、卵丘細胞の膨潤を促進する
- Author(s)
  岡本麻子、島田昌之、山下泰尚
- Organizer
  第55回日本卵子学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-26450381

1. 島田昌之 (20314742)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results

YAMASHITA Yasuhisa 山下 泰尚

山下 泰尚 ヤマシタ ヤスヒサ

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Analysis and application of follicular somatic cell-dependent oocyte metabolic regulation and epigenome regulation controled by iron during follicular development.Principal InvestigatorOngoing

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Exploration of oocyte maturation inducing factor by analysis of time-specific regulation of ADAM17 substrate specificity during follicular development and ovulation process.Principal Investigator

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The exploitation of IVG system based on selection of dominant follicle dependent on protesterone deactivation enzyme.Principal Investigator

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The study for development of in vitro culture system of mammalian oocyte by global analysis of cumulus cell-stimulating substrate during ovulating processPrincipal Investigator

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卵丘細胞のERKとPKB系に着目した哺乳動物卵子減数分裂再開制御因子の探索

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The exploitation of novel in vitro maturation system of mammalian cumulus-oocyte complex that enhances SREBP gene in cumulus cellsPrincipal Investigator

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[Book] 哺乳動物卵子の成熟と排卵のメカニズム（日本卵子学会胚培養士テキスト）2016

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[Book] 生殖医学研究の最前線（排卵期における顆粒膜細胞分泌因子の発現・分泌制御機構とその生理的役割）2014

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[Book] 生体の科学(64(5),ISSN 1883-5503) 卵の成熟におけるEGF受容体の活性化と活性化因子2013

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[Book] 生体の科学（卵の成熟におけるEGF受容体の活性化と活性化因子）2013

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[Book] 卵子学:卵子成熟時および初期胚発達期における代謝機構2011

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[Book] 卵子学2011

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[Book] 卵子学:卵子成熟時および初期胚発達期における代謝機構2011

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[Book] 卵子・初期胚の代謝機構2009

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[Journal Article] Developmental of artificial insemination technique in pig production based on the evidence of physiology and molecular biology in reproductive organs2016

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YAMASHITA Yasuhisa 山下泰尚

山下泰尚ヤマシタヤスヒサ

[Journal Article] Protein kinase C (PKC) increases TACE/ADAM17 enzyme　activity in porcine ovarian somatic cells, which is essential for granulosa cell luteinization and oocyte maturation.2014