Fukunaga Koya 福永航也

Researcher Number	50506722
Other IDs
Affiliation (Current)	2026: 国立研究開発法人理化学研究所, 生命医科学研究センター, 上級研究員 2026: 国立医薬品食品衛生研究所, 医薬安全科学部, 主任研究官
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2022: 国立医薬品食品衛生研究所, 医薬安全科学部, 主任研究官 2018 – 2019: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 42010:Animal production science-related / Veterinary medical science
Keywords	Principal Investigator MHC / 乳房炎 / ロングリードシークエンシング / CNV / WGS / 遺伝的多様性 / ゲノム / ウシ / 全ゲノム関連解析 / 乳房炎の慢性化 … More / 慢性感染 / ホルスタイン / 黄色ブドウ球菌性乳房炎 / ゲノムワイド関連解析 / 黄色ブドウ球菌 / BoLA / GWAS / 牛 Less

Sequencing-based identification of mastitis resistance genes in the bovine MHC region for novel disease control strategiesPrincipal Investigator
- Principal Investigator
  
  Fukunaga Koya
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Institute of Physical and Chemical Research
  National Institute of Health Sciences
Genome wide association study to identify the susceptibility of staphylococcus aureus-induced mastitis in Holstein cattle and to estimate the riskPrincipal Investigator
- Principal Investigator
  
  Fukunaga Koya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023 2022 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] Association of HLA-A11:01, HLA-B39:01, and HLA-B56:03 with salazosulfapyridine-induced cutaneous adverse drug reactions2024
- Author(s)
  Fukunaga Koya、Tsukagoshi Eri、Nakamura Ryosuke、Matsunaga Kayoko、Ozeki Takeshi、Watanabe Hideaki、Hasegawa Akito、Hama Natsumi、Kurata Maiko、Mizukawa Yoshiko、Watanabe Yuko、Yamaguchi Yukie、Niihara Hiroyuki、Morita Eishin、Asada Hideo、Abe Riichiro、Saito Yoshiro、Mushiroda Taisei
- Journal Title
  
  The Journal of Allergy and Clinical Immunology: In Practice
  
  Volume: 12 Issue: 5 Pages: 1355-1358
- DOI
  10.1016/j.jaip.2024.02.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05978, KAKENHI-PROJECT-22K06760, KAKENHI-PROJECT-24K11479
[Journal Article] Differential Effects of HLA-B8727;15:11 and HLA-A8727;31:01 on Carbamazepine-Induced Cutaneous Adverse Reactions.2023
- Author(s)
  Fukunaga K, Tsukagoshi E, Kurata M, Mizukawa Y, Niihara H, Morita E, Watanabe Y, Yamaguchi Y, Watanabe H, Nakajima S, Nomura T, Kabashima K, Tohyama M, Azukizawa H, Asada H, Hasegawa A, Hama N, Ozeki T, Mashimo Y, Sekine A, Matsunaga K, Tanaka Y, Nakamura R, Abe R, Mushiroda T, Saito Y.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 144（４） Issue: 4 Pages: 908-911
- DOI
  10.1016/j.jid.2023.09.282
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16222, KAKENHI-PROJECT-22K05978, KAKENHI-PROJECT-22K06760, KAKENHI-PROJECT-21K08306, KAKENHI-PROJECT-24K11479
[Journal Article] Genotyping, characterization, and imputation of known and novel CYP2A6 structural variants using SNP array data2023
- Author(s)
  Langlois Alec W. R.、El-Boraie Ahmed、Pouget Jennie G.、Cox Lisa Sanderson、Ahluwalia Jasjit S.、Fukunaga Koya、Mushiroda Taisei、Knight Jo、Chenoweth Meghan J.、Tyndale Rachel F.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: in press Issue: 8 Pages: 533-541
- DOI
  10.1038/s10038-023-01148-y
- Data Source
  KAKENHI-PROJECT-22K05978
[Journal Article] Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes2022
- Author(s)
  Langlois Alec W.R.、El-Boraie Ahmed、Fukunaga Koya、Mushiroda Taisei、Kubo Michiaki、Lerman Caryn、Knight Jo、Scherer Steven E.、Chenoweth Meghan J.、Tyndale Rachel F.
- Journal Title
  
  Pharmacogenetics and Genomics
  
  Volume: 32 Issue: 4 Pages: 159-172
- DOI
  10.1097/fpc.0000000000000466
- Data Source
  KAKENHI-PROJECT-22K05978
[Journal Article] BoLA-DRB3 polymorphism is associated with differential susceptibility to bovine leukemia virus-induced lymphoma and proviral load.2020
- Author(s)
  Lo C-W, Borjigin L, Saito S, Fukunaga K., Saitou E, Okazaki K, Mizutani T, Wada S, Takeshima S, Aida Y
- Journal Title
  
  Viruses
  
  Volume: 12 Issue: 3 Pages: 352-352
- DOI
  10.3390/v12030352
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08060, KAKENHI-PROJECT-17K15387
[Journal Article] Genomewide Association Study Confirming the Association of NAT2 with Susceptibility to Antituberculosis Drug-Induced Liver Injury in Thai Patients2019
- Author(s)
  Suvichapanich S, Wattanapokayakit S, Mushiroda T, Yanai H, Chuchottawon C, Kantima T, Nedsuwan S, Suwankesawong W, Sonsupap C, Pannarunothai R, Tumpattanakul S, Bamrungram W, Chaiwong A, Mahasirimongkol S, Mameechai S, Panthong W, Klungtes N, Munsoo A, Chauychana U, Maneerat M, Fukunaga K, Omae Y, Tokunaga K
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 63 Issue: 8 Pages: 2692-2718
- DOI
  10.1128/aac.02692-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15041, KAKENHI-PROJECT-17K15387
[Journal Article] GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes2018
- Author(s)
  Yoshihama T, Fukunaga K, Hirasawa A, Nomura H, Akahane T, Kataoka F, Yamagami W, Aoki D, Mushiroda T
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 51 Pages: 29789-29800
- DOI
  10.18632/oncotarget.25712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09297, KAKENHI-PROJECT-17K19611, KAKENHI-PROJECT-17K15387, KAKENHI-PROJECT-16K11155
[Patent] 薬物動態関連遺伝子の網羅的配列解析法とそれに使用されるプライマーセット2019
- Inventor(s)
  莚田泰誠、福永航也
- Industrial Property Rights Holder
  莚田泰誠、福永航也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-001821
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K15387
[Presentation] Differential effects of HLA-B*15:11 and HLA-A*31:01 on carbamazepine-induced cutaneous adverse reactions2024
- Author(s)
  Koya Fukunaga, Eri Tsukagoshi, Maiko Kurata et al.
- Organizer
  69th Annual Meeting of the Japan Society of Human Genetics
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] ファーマコゲノミクス情報の活用を考える ~医薬品の研究開発から販売後調査まで~2024
- Author(s)
  福永航也
- Organizer
  第45回日本臨床薬理学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] Update on the Re-sequencing Project of 1,000 Southeast Asian Individuals Using the 100 Pharmacogene; Next Generation Sequencing Panel.2024
- Author(s)
  Koya Fukunaga
- Organizer
  The 11th Southeast Asian Pharmacogenomics Research Network Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] サラゾスルファピリジン誘発薬疹に関連する HLA-A*11:01、HLA-B*39:01 および HLA-B*56:03 の同定2024
- Author(s)
  福永航也, 塚越絵里, 中村亮介, 松永佳世子, 大関健志, 渡辺秀晃, 長谷川瑛人, 濱菜摘, 倉田麻衣子, 水川良子, 渡邉裕子, 山口由衣, 新原寛之, 森田栄伸, 浅田秀夫, 阿部理一郎, 斎藤嘉朗, 莚田泰誠
- Organizer
  第32回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] PK-phenome解析を用いたサラゾスルファピリジン誘発薬疹に関連するN-アセチルトランスフェラーゼ2 推定酵素活性との関連性同定2024
- Author(s)
  福永航也、塚越絵里、中村亮介、松永佳世子、大関健志、渡辺秀晃、長谷川瑛人、濱菜摘、倉田麻衣子、水川良子、渡邉裕子、山口由衣、新原寛之、森田栄伸、浅田秀夫、阿部理一郎、斎藤嘉朗、莚田泰誠
- Organizer
  第45回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] shortHLAseq:8 座の HLA 遺伝子領域を short-range PCR で増幅するアンプリコンシークエンシング法の開発2024
- Author(s)
  福永航也, 重水大智, 莚田泰誠
- Organizer
  第32回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] ウシおよびヒトのMHCゲノムの多様性と感染症・食物性/薬物性アレルギーとの関連2023
- Author(s)
  福永航也
- Organizer
  第166回　日本獣医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] corePGseq: a targeted sequencing panel of 18 pharmacogenes including 4 HLA genes and essential non-coding regions2022
- Author(s)
  Koya Fukunaga,Taisei Mushiroda
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-22K05978
[Presentation] ウシMHCクラスⅡ 6遺伝子のコピー数とNGS解析を組み合わせた新規アリル同定およびそのハプロタイプ構造の推定2020
- Author(s)
  福永航也、山下祐輔、八木沢拓也
- Organizer
  第29回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-17K15387

1. NOMURA Hiyoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 濱菜摘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 大前陽輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 岡崎克則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukunaga Koya 福永 航也

Research Projects

Research Products

Co-Researchers

Sequencing-based identification of mastitis resistance genes in the bovine MHC region for novel disease control strategiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome wide association study to identify the susceptibility of staphylococcus aureus-induced mastitis in Holstein cattle and to estimate the riskPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of HLA-A11:01, HLA-B39:01, and HLA-B56:03 with salazosulfapyridine-induced cutaneous adverse drug reactions2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential Effects of HLA-B8727;15:11 and HLA-A8727;31:01 on Carbamazepine-Induced Cutaneous Adverse Reactions.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genotyping, characterization, and imputation of known and novel CYP2A6 structural variants using SNP array data2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BoLA-DRB3 polymorphism is associated with differential susceptibility to bovine leukemia virus-induced lymphoma and proviral load.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genomewide Association Study Confirming the Association of NAT2 with Susceptibility to Antituberculosis Drug-Induced Liver Injury in Thai Patients2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes2018

Author(s)

Journal Title

DOI

Data Source

[Patent] 薬物動態関連遺伝子の網羅的配列解析法とそれに使用 されるプライマーセット2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] Differential effects of HLA-B*15:11 and HLA-A*31:01 on carbamazepine-induced cutaneous adverse reactions2024

Author(s)

Organizer

Data Source

[Presentation] ファーマコゲノミクス情報の活用を考える ~医薬品の研究開発から販売後調査まで~2024

Author(s)

Organizer

Data Source

[Presentation] Update on the Re-sequencing Project of 1,000 Southeast Asian Individuals Using the 100 Pharmacogene; Next Generation Sequencing Panel.2024

Author(s)

Organizer

Data Source

[Presentation] サラゾスルファピリジン誘発薬疹に関連する HLA-A*11:01、HLA-B*39:01 および HLA-B*56:03 の同定2024

Author(s)

Organizer

Data Source

[Presentation] PK-phenome解析を用いたサラゾスルファピリジン 誘発薬疹に関連するN-アセチルトランスフェラーゼ2 推定酵素活性との関連性同定2024

Author(s)

Organizer

Data Source

[Presentation] shortHLAseq:8 座の HLA 遺伝子領域を short-range PCR で増幅する アンプリコンシークエンシング法の開発2024

Author(s)

Fukunaga Koya 福永航也

[Patent] 薬物動態関連遺伝子の網羅的配列解析法とそれに使用されるプライマーセット2019

[Presentation] Differential effects of HLA-B15:11 and HLA-A31:01 on carbamazepine-induced cutaneous adverse reactions2024

[Presentation] サラゾスルファピリジン誘発薬疹に関連する HLA-A11:01、HLA-B39:01 および HLA-B*56:03 の同定2024

[Presentation] PK-phenome解析を用いたサラゾスルファピリジン誘発薬疹に関連するN-アセチルトランスフェラーゼ2 推定酵素活性との関連性同定2024

[Presentation] shortHLAseq:8 座の HLA 遺伝子領域を short-range PCR で増幅するアンプリコンシークエンシング法の開発2024