Ohnishi Naomi 大西なおみ

Researcher Number	50507217
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 公益財団法人がん研究会, がんプレシジョン医療研究センターがんオーダーメイド医療開発プロジェクト, 研究員 2017: 公益財団法人がん研究会, がんプレシジョン医療研究センター, 研究員 2015: 公益財団法人がん研究会, その他部局等, 研究員 2015: 北海道大学, 人獣共通感染症リサーチセンター, 助教 2014: 北海道大学, 学内共同利用施設等, 助教 … More 2012 – 2013: 北海道大学, 人獣共通感染症リサーチセンター, 助教 2010 – 2011: Hokkaido University, 遺伝子病制御研究所, その他 2009: Hokkaido University, 遺伝子病制御研究所, 特任助教 Less
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor biology / Bacteriology (including mycology) / Pathological medical chemistry Except Principal Investigator Applied veterinary science
Keywords	Principal Investigator 腎癌 / エクソソーム / 腎細胞癌 / CA9 / がん微小環境 / 癌関連繊維芽細胞 / 癌関連線維芽細胞 / ワールブルグ効果 / 炭疽菌 / 細菌 … More / 炭疽 / ワクチン抗原 / 感染症 / 分子設計 / 抗原 / ワクチン / トランスジェニックマス / CagA / H.pylori … More Except Principal Investigator トランスジェニックマウス / レセプター / ウマ / ヘルペスウイルス Less

がん悪性化における腎癌部由来エクソソーム特異的分子の機能解明Principal Investigator
- Principal Investigator
  
  大西なおみ
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Elucidation of Warburg effect induced by cancer-associated fibroblastsPrincipal Investigator
- Principal Investigator
  
  Ohnishi Naomi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Japanese Foundation for Cancer Research
Development of a de novo designed molecule to develop structure-based vaccine against anthraxPrincipal Investigator
- Principal Investigator
  
  Ohnishi Naomi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Japanese Foundation for Cancer Research
  Hokkaido University
Generation of transgenic mice expressing equine herpesvirus-1 receptor and its application for antiviral strategies
- Principal Investigator
  
  KIMURA TAKASHI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
ヘリコバクター・ピロリcagA遺伝子導入マウスを用いた胃発癌機構の解析Principal Investigator
- Principal Investigator
  
  大西なおみ
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University

All 2019 2018 2017 2015 2014 2013 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Novel Sequence Type in Bacillus cereus Strains Associated with Nosocomial Infections and Bacteremia, Japan.2019
- Author(s)
  Akamatsu R, Suzuki M, Okinaka K, Sasahara T, Yamane K, Suzuki S, Fujikura D, Furuta Y, Ohnishi N, Esaki M, Shibayama K, Higashi H
- Journal Title
  
  Emerging Infectious Diseases
  
  Volume: 25(5) Issue: 5 Pages: 883-890
- DOI
  10.3201/eid2505.171890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08846, KAKENHI-PROJECT-17K14999, KAKENHI-PROJECT-15K08863, KAKENHI-PROJECT-18K19436, KAKENHI-PROJECT-17H01679, KAKENHI-PROJECT-16H06279
[Journal Article] Exogenous Expression of Equine MHC Class I Molecules in Mice Increases Susceptibility to Equine Herpesvirus 1 Pulmonary Infection2019
- Author(s)
  Minato Erina、Aoshima Keisuke、Kobayashi Atsushi、Ohnishi Naomi、Sasaki Nobuya、Kimura Takashi
- Journal Title
  
  Veterinary Pathology
  
  Volume: 印刷中 Issue: 5 Pages: 703-710
- DOI
  10.1177/0300985819834616
- NAID
  120006781559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-17K14999, KAKENHI-PROJECT-16H05022
[Journal Article] Loss of Bacitracin Resistance Due to a Large Genomic Deletion among Bacillus anthracis Strains2018
- Author(s)
  Furuta Y, Harima H, Ito E, Maruyama F, Ohnishi N, Osaki K, Ogawa H, Squarre D, Hang'ombe BM, Higashi H
- Journal Title
  
  mSystems
  
  Volume: 3 Issue: 5 Pages: 00182-18
- DOI
  10.1128/msystems.00182-18
- NAID
  120006543305
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19436, KAKENHI-PROJECT-17K14999, KAKENHI-PROJECT-16H01782, KAKENHI-PROJECT-17H01679
[Journal Article] EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.2017
- Author(s)
  Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K.
- Journal Title
  
  Neoplasia
  
  Volume: 19 Issue: 3 Pages: 185-195
- DOI
  10.1016/j.neo.2016.12.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-15K14377, KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-17K14999, KAKENHI-PROJECT-26710007
[Journal Article] Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin2017
- Author(s)
  Jingushi Kentaro、Uemura Motohide、Ohnishi Naomi、Nakata Wataru、Fujita Kazutoshi、Naito Takuya、Fujii Risa、Saichi Naomi、Nonomura Norio、Tsujikawa Kazutake、Ueda Koji
- Journal Title
  
  International Journal of Cancer
  
  Volume: 142 Issue: 3 Pages: 607-617
- DOI
  10.1002/ijc.31080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-17K14999, KAKENHI-PROJECT-26710007, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17K17848
[Journal Article] A novel multiplex PCR discriminates Bacillus anthracis and its genetically related strains from other Bacillus cereus group species2015
- Author(s)
  Ogawa H., Fujikura D., Ohnuma M., Ohnishi N., Hang'ombe B.M., Mimuro M., Ezaki T., Mweene A.S., Higashi H
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0122004-e0122004
- DOI
  10.1371/journal.pone.0122004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659120, KAKENHI-PROJECT-25670206, KAKENHI-PROJECT-25870017, KAKENHI-PROJECT-26293095
[Journal Article] <i>Bacillus cereus</i> from the environment is genetically related to the highly pathogenic <i>B. cereus</i> in Zambia2015
- Author(s)
  Ogawa H, Ohnuma M, Squarre D, Mweene AS, Ezaki T, Fujikura D, Ohnishi N, Thomas Y, Hang'ombe BM, Higashi H.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 77 Issue: 8 Pages: 993-995
- DOI
  10.1292/jvms.15-0059
- NAID
  130005094678
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670206, KAKENHI-PROJECT-25870017
[Journal Article] Genome Sequence of Bacillus anthracis outbreak strain in Zambia2014
- Author(s)
  Ohnishi N., Maruyama F., Ogawa H., Kachi H., Yamada S., Fujikura D., Nakagawa I., Hang'ombe B.M., Thomas Y., Mweene A.S., Higashi H.
- Journal Title
  
  2011. Genome Announc
  
  Volume: 2 Issue: 2
- DOI
  10.1128/genomea.00116-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390076, KAKENHI-PROJECT-24659120, KAKENHI-PUBLICLY-25125708, KAKENHI-PROJECT-25670206
[Patent] バイオマーカー、疾患関連遺伝子の探索方法、及び腎がんマーカー2019
- Inventor(s)
  植田幸嗣, 大西なおみ, 計6名
- Industrial Property Rights Holder
  植田幸嗣, 大西なおみ, 計6名
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K14999
[Patent] 胃がんマーカー、及びこれを用いた検査方法2019
- Inventor(s)
  植田幸嗣, 大西なおみ
- Industrial Property Rights Holder
  植田幸嗣, 大西なおみ
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-161687
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] Exosome secreted from gastric cancer cells promote apoptosis resistance via deregulation of intracellular pH homeostasis2019
- Author(s)
  Naomi Ohnishi, Naomi Saichi, Risa Fujii, Kentaro Murakami, Masayuki Kano, Hisahiro Matsubara, Koji Ueda
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] Gastric cancer cell-derived exosomes deliver anti-apoptotic signals to tumor microenvironment2019
- Author(s)
  Naomi Ohnishi, Naomi Saichi, Risa Fujii, Kentaro Murakami, Hisahiro Matsubara, Koji Ueda
- Organizer
  11thJCA-AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] 胃癌由来エクソソームによる癌微小環境中へのアポトーシス耐性能の伝達2019
- Author(s)
  大西なおみ、最知直美、藤井理沙、村上健太郎、松原久裕、植田幸嗣
- Organizer
  日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] Comprehensive proteomic profiling of serum exosomes identifies novel biomarkers for early detection of gastric cancer2018
- Author(s)
  Naomi Ohnishi, Naomi Saichi, Risa Fujii, Kentaro Murakami, Hisahiro Matsubara, Koji Ueda
- Organizer
  HUPO2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] Exosomes secreted from gastric cancer cells deliver anti-apoptotic signals to tumor microenvironment2018
- Author(s)
  Naomi Ohnishi, Naomi Saichi, Risa Fujii, Kentaro Murakami, Hisahiro Matsubara, Koji Ueda
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] Gastric cancer cell-derived exosomes deliver anti-apoptotic signals to tumor microenvironment2018
- Author(s)
  Naomi Ohnishi, Naomi Saichi, Risa Fujii, Kentaro Murakami, Hisahiro Matsubara, Koji Ueda
- Organizer
  JSEV2018
- Data Source
  KAKENHI-PROJECT-17K14999
[Presentation] 炭疽の制圧を目指して-Bacillus 属細菌の病態-遺伝学的連関解析2015
- Author(s)
  大西なおみ
- Organizer
  第23回分子寄生虫学ワークショップ・第13回分子寄生虫・マラリア研究フォーラム合同大会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2015-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] Genetic Profiles of Bacillus anthracis Indigenous to Zambia and Characterization of Bacillus Species Causing Anthrax-like Disease2015
- Author(s)
  Naomi Ohnishi
- Organizer
  2015JSME annual meeting and 7th JTK symposium
- Place of Presentation
  Ibaraki
- Year and Date
  2015-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] Development of a Novel Anthrax Vaccine Antigen and Analysis of Molecular Pathogenicity in Bacillus anthracis Infection2014
- Author(s)
  Fujikura D, Mutoh M, Ohnishi N, Ohnuma M, Ogawa H, Bernard MH, Aaron SM, Higashi H.
- Organizer
  Asian-African Research Forum on Emerging and Reemerging Infections 2014
- Place of Presentation
  仙台国際センター（宮城県）
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] De novo designed molecule to develop structure-based vaccine against Anthrax2014
- Author(s)
  Ohnishi N, Mutoh M, Fujikura D, Igarashi M, Higashi H. Mutoh M, Fujikura D, Igarashi M, Higashi H.
- Organizer
  American Society for Microbiology 114th general meeting
- Place of Presentation
  Boston Convention & Exhibition Center (Boston, Massachusetts, USA)
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] タンパク質四次構造情報に基づく新規炭疽ワクチン抗原の分子設計2014
- Author(s)
  武藤芽未, 大西なおみ, 五十嵐学, 藤倉大輔, 東秀明
- Organizer
  第3回感染症若手フォーラム
- Place of Presentation
  やすらぎ伊王島（長崎県）
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] 新規炭疽ワクチン抗原の分子設計2014
- Author(s)
  大西なおみ, 武藤芽未, 五十嵐学, 藤倉大輔, 東秀明
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  船堀タワーホール（東京都）
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] 新規抗炭疽ワクチンの開発に向けた人工設計タンパク質の作出2013
- Author(s)
  武藤芽未, 大西なおみ, 五十嵐学, 藤倉大輔, 東秀明
- Organizer
  第7回細菌学若手コロッセウム
- Place of Presentation
  広島エアポートホテル（広島県）
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] De novo designed molecule to develop structure-based vaccine against Anthrax2013
- Author(s)
  Ohnishi N, Muto M, Fujikura D, Igarashi M, Higashi H.
- Organizer
  The 12th Awaji International Forum on infection and Immunity
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] Transgenic Study of the Helicobacter pylori CagA Oncoprotein in Mice2010
- Author(s)
  大西なおみ
- Organizer
  8^<th> Joint Conference of the American Association for Cancer Research and Japanese Cancer Association
- Place of Presentation
  Waikoloa Hawaii, USA
- Year and Date
  2010-02-08
- Data Source
  KAKENHI-PROJECT-21790301
[Presentation] Helicobacter pylori Western CagA is less oncogenic than East Asian CagA in mice2009
- Author(s)
  大西なおみ
- Organizer
  2009 29^<th> International Symposium on Cancer
- Place of Presentation
  札幌市北海道大学
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PROJECT-21790301
[Presentation] Helicobacter pylori Western CagA is less oncogenic than East Asian CagA in mice2009
- Author(s)
  大西なおみ
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21790301
[Presentation] 炭疽の制圧を目指した疫学調査と新規ワクチンの開発
- Author(s)
  大西なおみ、藤倉大輔、五十嵐学、小川寛人、東秀明
- Organizer
  第79回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北海道大学
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] ザンビア共和国で単離された炭疽菌の全ゲノム解析に基づくゲノム疫学の構築
- Author(s)
  大西なおみ、丸山史人、大崎研、東秀明
- Organizer
  第88回日本細菌学会学術総会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] 炭疽の制圧を目指した疫学調査と新規ワクチンの開発
- Author(s)
  大西なおみ
- Organizer
  第2回感染症国際研究センターシンポジウム
- Place of Presentation
  東京大学（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] 炭疽の制圧を目指した疫学調査と新規ワクチンの開発
- Author(s)
  大西なおみ、藤倉大輔、五十嵐学、赤松玲子、豊間根耕地、東秀明
- Organizer
  第81回日本細菌学会北海道支部学術総会
- Place of Presentation
  札幌医科大学
- Year and Date
  2014-08-29 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-25670206
[Presentation] De novo designed molecule to develop structure-based vaccine against Anthrax
- Author(s)
  Ohnishi N, Mutoh M, Fujikura D, Igarashi M, Higashi H. Mutoh M, Fujikura D, Igarashi M, Higashi H.
- Organizer
  American Society for Microbiology 114th general meeting
- Place of Presentation
  Boston, Massachusetts, USA
- Year and Date
  2014-05-17 – 2014-05-20
- Data Source
  KAKENHI-PROJECT-25670206

1. KIMURA TAKASHI (90261338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SASAKI Nobuya (20302614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SUZUKI Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. MATSUDA Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. UEDA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 東秀明

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 小林篤史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohnishi Naomi 大西 なおみ

Research Projects

Research Products

Co-Researchers

がん悪性化における腎癌部由来エクソソーム特異的分子の機能解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Warburg effect induced by cancer-associated fibroblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a de novo designed molecule to develop structure-based vaccine against anthraxPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of transgenic mice expressing equine herpesvirus-1 receptor and its application for antiviral strategies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヘリコバクター・ピロリcagA遺伝子導入マウスを用いた胃発癌機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Novel Sequence Type in Bacillus cereus Strains Associated with Nosocomial Infections and Bacteremia, Japan.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exogenous Expression of Equine MHC Class I Molecules in Mice Increases Susceptibility to Equine Herpesvirus 1 Pulmonary Infection2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Loss of Bacitracin Resistance Due to a Large Genomic Deletion among Bacillus anthracis Strains2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel multiplex PCR discriminates Bacillus anthracis and its genetically related strains from other Bacillus cereus group species2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>Bacillus cereus</i> from the environment is genetically related to the highly pathogenic <i>B. cereus</i> in Zambia2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Genome Sequence of Bacillus anthracis outbreak strain in Zambia2014

Author(s)

Journal Title

DOI

Data Source

[Patent] バイオマーカー、疾患関連遺伝子の探索方法、及び腎がんマーカー2019

Ohnishi Naomi 大西なおみ

[Presentation] 胃癌由来エクソソームによる癌微小環境中へのアポトーシス耐性能の伝達2019