SOBUE SAYAKA 祖父江沙矢加

… Alternative Names

SOBUE Sayaka 祖父江沙矢加

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Researcher Number	50513347
Other IDs
Affiliation (Current)	2025: 中部大学, 臨床検査技術教育・実習センター, 准教授
Affiliation (based on the past Project Information) *help	2025: 中部大学, 臨床検査技術教育・実習センター, 准教授 2021 – 2023: 中部大学, 臨床検査技術教育・実習センター, 准教授 2016 – 2020: 中部大学, 臨床検査技術教育・実習センター, 講師 2015: 中部大学, 生命健康科学部, 助教 2014 – 2015: 中部大学, 臨床検査技術教育・実習センター, 助教 … More 2011 – 2013: 中部大学, 生命健康科学部, 助教 2012: 中部大学, 臨床検査技術教育・実習センター, 助教 2008 – 2010: Chubu University, 生命健康科学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Laboratory medicine / Eating habits Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Laboratory animal science / Hygiene
Keywords	Principal Investigator 疾患モデル動物 / 筋萎縮 / 非アルコール性脂肪肝炎 / 水素 / モノクローナル抗体 / トランスジェニックマウス / CD109 / 分化誘導療法 / 白血病 / sphingosine kinase 1 / 分子標的療法 / 赤白血病 / SPHK1 … More Except Principal Investigator … More 胸腺腫 / 遺伝子変異 / 胸腺腫発症ラット / B型胸腺腫 / ゲノム編集 / ミトコンドリア / 次世代シークエンス / 筋萎縮 / 発癌 / 扁平上皮癌 / 酸化ストレス / 水素 / 炎症 / 線虫 / 皮膚癌 / 紫外線 / 分子状水素 Less

筋肉の萎縮が核－細胞質輸送因子の変異によって誘導される機構の解明Principal Investigator
- Principal Investigator
  
  祖父江沙矢加
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
胸腺腫発症ラットの原因遺伝子変異導入マウスを用いたヒトB型胸腺腫の病態解明
- Principal Investigator
  
  市原正智
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Chubu University
Pathophysiological analysis of animal models of disease with the goal of establishing animal models of sarcopeniaPrincipal Investigator
- Principal Investigator
  
  Sobue Sayaka
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
Identification and functional analysis of causative genes for thymoma and muscle atrophy developing in BUF/Mna rats
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Chubu University
Molecular hydrogen control the disease state of nonalcoholic steatohepatitis and prevent cancer by modifying gene expression by influencing the epigenetic mechanism of histone methylation modificationPrincipal Investigator
- Principal Investigator
  
  SOBUE Sayaka
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Chubu University
Molecular hydrogen attenuates UV-induced tissue injury in Caenorhabditis elegans and mouse
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Chubu University
Elucidation of CD109 function and its tumor promotion using transgenic mice overexpressing CD109Principal Investigator
- Principal Investigator
  
  SOBUE Sayaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Chubu University
HMBA-induced erythroid differentiation decreases sphingosine kinase 1 gene expression of a mouse erythroleukemia cell linePrincipal Investigator
- Principal Investigator
  
  SOBUE Sayaka
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Laboratory medicine
- Research Institution
  Chubu University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles - Meta-analyses of gene expression profiles2018
- Author(s)
  Hiroshi Nishiwak,i, Ito Mikako , Shuto Negishi, Sobue Sayaka, Ichihara Masatoshi, Ohno Kinji
- Journal Title
  
  Free Radic Res.
  
  Volume: - Issue: 4 Pages: 1-12
- DOI
  10.1080/10715762.2018.1439166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-26870682
[Journal Article] Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response2017
- Author(s)
  Sobue Sayaka、Inoue Chisato、Hori Fumiko、Qiao Shanlou、Murate Takashi、Ichihara Masatoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 493 Issue: 1 Pages: 318-324
- DOI
  10.1016/j.bbrc.2017.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870682
[Journal Article] Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel2016
- Author(s)
  Sobue S, Mizutani N, Aoyama Y, Kawamoto Y, Suzuki M, Nozawa Y, Ichihara M, Murate T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 479 Issue: 4 Pages: 808-813
- DOI
  10.1016/j.bbrc.2016.09.128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26870682
[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016
- Author(s)
  祖父江沙矢加、市原正智
- Journal Title
  
  中部大学生命健康科学研究所紀要
  
  Volume: 12 Pages: 38-41
- NAID
  120006520501
- Open Access
- Data Source
  KAKENHI-PROJECT-15K06812
[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016
- Author(s)
  祖父江沙矢加、市原正智
- Journal Title
  
  中部大学生命健康科学研究所紀要
  
  Volume: 12 Pages: 38-41
- NAID
  120006520501
- Open Access
- Data Source
  KAKENHI-PROJECT-26870682
[Journal Article] Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR2016
- Author(s)
  Yuka Aoyama, Sayaka Sobue, Naoki Mizutani, Chisato Inoue, Yoshiyuki Kawamoto, Yuji Nishizawa, Masatoshi Ichihara, Mamoru Kyogashima, Motoshi Suzuki, Yoshinoti Nozawa, Takashi Murate
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 486 Issue: 2 Pages: 551-557
- DOI
  10.1016/j.bbrc.2017.03.084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-15K10883, KAKENHI-PROJECT-17K09025, KAKENHI-PROJECT-26870682
[Journal Article] Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.2016
- Author(s)
  Mizutani N, Omori Y, Kawamoto Y, Sobue S, Ichihara M, Suzuki M, Kyogashima M, Nakamura M, Tamiya-Koizumi K, Nozawa Y, Murate T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 470 Issue: 4 Pages: 851-856
- DOI
  10.1016/j.bbrc.2016.01.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06812, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26460674
[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016
- Author(s)
  祖父江沙矢加、市原正智
- Journal Title
  
  中部大学生命健康科学研究所紀要
  
  Volume: 12 Pages: 38-41
- NAID
  120006520501
- Open Access
- Data Source
  KAKENHI-PROJECT-24590768
[Journal Article] Characterization of gene expression profiling of mouse tissues obtained during the postmortem interval2016
- Author(s)
  Sobue S, Sakata K, Sekijima Y, Qiao S, Murate T, Ichihara M.
- Journal Title
  
  Exp Mol Pathol.
  
  Volume: 100 Issue: 3 Pages: 482-92
- DOI
  10.1016/j.yexmp.2016.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870682
[Journal Article] Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.2015
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Iwamoto T, Qiao S, Ohkuwa T, Ichihara M.
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 403 Pages: 231-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870682
[Journal Article] Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.2015
- Author(s)
  Ichihara M, Sobue S, Ito M, Ito M, Hirayama M, Ohno K.
- Journal Title
  
  Med Gas Res
  
  Volume: 5 Issue: 1 Pages: 12-12
- DOI
  10.1186/s13618-015-0035-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06812, KAKENHI-PROJECT-15K09350, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-24590768
[Journal Article] Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.2015
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Iwamoto T, Qiao S, Ohkuwa T, Ichihara M
- Journal Title
  
  Mol Cell Biochem
  
  Volume: 403 Pages: 231-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590768
[Journal Article] Photoshopを用いた画像解析の検討.2014
- Author(s)
  岩田晃裕、土本詩織、市原正智、祖父江沙矢加
- Journal Title
  
  社団法人　愛知県臨床衛生検査技師会誌　らぼ
  
  Volume: 65 Pages: 11-14
- Data Source
  KAKENHI-PROJECT-24590768
[Journal Article] Detection of a Soluble Form of CD109 in Serum of CD109 Transgenic and Tumor Xenografted Mice.2014
- Author(s)
  Sakakura H, Murakumo Y, Mii S, Hagiwara S, Kato T, Asai M, Hoshino A, Yamamoto N, Sobue S, Ichihara M, Ueda M, Takahashi M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e83385-e83385
- DOI
  10.1371/journal.pone.0083385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590479, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-25460493
[Journal Article] Photoshopを用いた画像解析の検討2014
- Author(s)
  岩田晃裕、土本詩織、市原正智、祖父江沙矢加
- Journal Title
  
  社団法人　愛知県臨床衛生検査技師会誌　らぼ
  
  Volume: 65 Pages: 11-14
- Data Source
  KAKENHI-PROJECT-26870682
[Journal Article] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6.2014
- Author(s)
  Miyata M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 445 Issue: 2 Pages: 504-10
- DOI
  10.1016/j.bbrc.2014.02.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24790298, KAKENHI-PROJECT-24791182, KAKENHI-PROJECT-26870682
[Journal Article] Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.2013
- Author(s)
  Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S, Fujii S, Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1833 Pages: 1006-1016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532
[Journal Article] Epidermal Hyperplasia and AppendageAbnormalities in Mice Lacking CD109.2012
- Author(s)
  Mii S, Murakumo Y, Asai N, Jijiwa M, Hagiwara S, Kato T, Asai M, Enomoto A, Ushida K, Sobue S, Ichihara M, Takahashi M
- Journal Title
  
  Am J Pathol.
  
  Volume: 181 Pages: 1180-1189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532
[Journal Article] Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line2012
- Author(s)
  Ito H, Tanaka K, Hagiwara K, Kobayashi M, Hoshikawa A, Mizutani N, Takagi A, Kojima T, Sobue S, Ichihara M, Suzuki M, Tamiya-Koizumi K, Nakamura M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  MCF-7. J Biochem.
  
  Volume: 151 Pages: 599-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532
[Journal Article] Hasegawa T.Analysis of the pathological lesions of the lung in a mouse model of cutaneousinfection with Streptococcus pyogenes.2012
- Author(s)
  Minami M, Sobue S, Ichihara M
- Journal Title
  
  Pathol Int.
  
  Volume: 62 Pages: 99-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532
[Journal Article] Heterogeneous sphingosine-1-phosphate lyase gene expression and its regulatory mechanism in human lung cancer cell lines.2011
- Author(s)
  Ito H, Yoshida K, Murakami M, Hagiwara K, Sasaki N, Kobayashi M, Takagi A, Kojima T, Sobue S, Suzuki M, Tamiya-Koizumi K, Nakamura M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1811 Pages: 119-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532
[Journal Article] Sphingosine Kinase 1/S1P PathwayInvolvement in the GDNF-Induced GAP43Transcription.2011
- Author(s)
  Murakami M, Ito H, Hagiwara K, Kobayashi M, Hoshikawa A, Takagi A, Kojima T, Tamiya-Koizumi K, Sobue S, Ichihara M, Suzuki M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  J Cell Biochem.
  
  Volume: 112 Pages: 3449-3458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532
[Journal Article] ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells : the role of COUP-TFI.2010
- Author(s)
  Murakami M, Ito H, Hagiwara K, Yoshida K, Sobue S, Ichihara M, Takagi A, Kojima T, Tanaka K, Koizumi-T K, Kyogashima M, Suzuki M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  J Neurochem. 112
  
  Pages: 511-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin.2009
- Author(s)
  Ito H, Murakami M, Furuhata A, Gao S, Yoshida K, Sobue S, Hagiwara K, Takagi A, Kojima T, Suzuki M, Banno Y, Tanaka K, Tamiya-Koizumi K, Kyogashima M, Nozawa Y, Murate T.
- Journal Title
  
  Biochim Biophys Acta. 1789
  
  Pages: 681-690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines.2009
- Author(s)
  Furuhata A, Murakami M, Ito H, Gao S, Yoshida K, Sobue S, Kikuchi R, Iwasaki T, Takagi A, Kojima T, Suzuki M, Abe A, Naoe T, Murate T.
- Journal Title
  
  Leukemia. 23
  
  Pages: 1270-1277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization : alteration of AU-rich element-binding proteins.2008
- Author(s)
  Sobue S
- Journal Title
  
  Oncogene 27
  
  Pages: 6023-6033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat : relevance as a marker for daunorubicin sensitivity of leukemia cells.2008
- Author(s)
  Sobue S, Nemoto S, Murakami M, Ito H, Kimura A, Gao S, Furuhata A, Takagi A, Kojima T, Nakamura M, Ito Y, Suzuki M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  Int J Hematol. 87
  
  Pages: 266-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization : alteration of AU-rich element-binding proteins.2008
- Author(s)
  Sobue S, Murakami M, Banno Y, Ito H, Kimura A, Gao S, Furuhata A, Takagi A, Kojima T, Suzuki M, Nozawa Y, Murate T.
- Journal Title
  
  Oncogene. 27
  
  Pages: 6023-6033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] Characterization of myelodysplastic syndrome and aplastic anemia by immunostaining of p53 and hemoglobin F and karyotype analysis: differential diagnosis between refractory anemia and aplastic anemia.2008
- Author(s)
  Iwasaki T, Murakami M, Sugisaki C, Sobue S, Ohashi H, Asano H, Suzuki M, Nakamura S, Ito M, Murate T.
- Journal Title
  
  Pathol Int. 58
  
  Pages: 353-360
- NAID
  10027376865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Journal Article] Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat : relevance as a marker for daunorubicin sensitivity of leukemia cells.2008
- Author(s)
  Sobue S
- Journal Title
  
  Int J Hematol 87
  
  Pages: 266-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890251
[Presentation] 分子状水素はエピジェネティックに遺伝子発現を修飾するとともにmtUPRを誘導し生体を保護する2017
- Author(s)
  祖父江沙矢加、井上千聖、堀文子、西沢祐治、村手隆、市原正智
- Organizer
  第7 回日本分子状水素医学生物学会大会
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] 分子状水素はH3K27のメチル化状態を変化させ遺伝子発現を修飾しmtUPRを誘導する2017
- Author(s)
  祖父江沙矢加、井上千聖、堀文子、村手隆、市原正智
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] Molecular hydrogen activates the mitochondrial unfolded protein response via epigenetic histone modification and ameliorates ultraviolet light-induced damage in Caenorhabditis elegans2017
- Author(s)
  Sayaka Sobue, Chisato Inoue, Fumiko Hori, Takashi Murate, Masatoshi Ichihara
- Organizer
  8th World Congress on Targeting Mitochondria 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] 分子状水素による肝障害軽減作用の背景にあるミトコンドリア保護効果に関与する分子機構の解析2016
- Author(s)
  祖父江沙矢加、岡本陽、安形則雄、市原正智
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] 水素による紫外線障害軽減効果の線虫を用いた分子機構の解明2016
- Author(s)
  井上千聖、祖父江沙矢加、長谷川浩一、堀文子、市原正智
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] 水素ガスおよび水素水の併用投与が細胞内シグナル伝達に与える影響の検討2015
- Author(s)
  祖父江沙矢加、井上千聖、伊藤美佳子、大野欽司、伊藤雅史、市原正智
- Organizer
  第5回分子状水素医学シンポジウム
- Place of Presentation
  ウインクあいち (名古屋市)
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Development of effective method for preventing life environment factor-induced diseases using molecular hydrogen.2015
- Author(s)
  Sobue S, Ichihara M.
- Organizer
  ICITE for SD-2015
- Place of Presentation
  Chubu University (Kasugai)
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06812
[Presentation] 水素ガスおよび水素水の併用投与が細胞内シグナル伝達に与える影響の検討2015
- Author(s)
  祖父江沙矢加、井上千聖、伊藤美佳子、大野欽司、伊藤雅史、市原正智
- Organizer
  第5回分子状水素医学シンポジウム
- Place of Presentation
  ウインクあいち（愛知県・名古屋市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] Molecular hydrogen is a novel antioxidant to reduce oxidative stress and attenuate disease progression through modification of cell signaling and gene expressions.2015
- Author(s)
  Sobue S, Inoue C, Hori F, Ito M, Ohno K, Ichihara M.
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis &Antioxidants
- Place of Presentation
  Paris (France)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] Development of effective method for preventing life environment factor-induced diseases using molecular hydrogen.2015
- Author(s)
  Sobue S, Ichihara M.
- Organizer
  ICITE for SD-2015
- Place of Presentation
  Chubu University (Kasugai)
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] Molecular hydrogen is a novel antioxidant to reduce oxidative stress and attenuate disease progression through modification of cell signaling and gene expressions.2015
- Author(s)
  Sobue S, Inoue C, Hori F, Ito M, Ohno K, Ichihara M.
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis &Antioxidants
- Place of Presentation
  Paris (France)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06812
[Presentation] Development of effective method for preventing life environment factor-induced diseases using molecular hydrogen.2015
- Author(s)
  Sobue S, Ichihara M.
- Organizer
  ICITE for SD-2015
- Place of Presentation
  Chubu University (Kasugai)
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Molecular hydrogen is a novel antioxidant to reduce oxidative stress and attenuate disease progression through modification of cell signaling and gene expressions.2015
- Author(s)
  Sobue S, Inoue C, Hori F, Ito M, Ohno K, Ichihara M.
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis &Antioxidants
- Place of Presentation
  Paris (France)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 当院における血管内大細胞型B細胞性リンパ腫の特徴2014
- Author(s)
  祖父江沙矢加、新川和功、三田村桂二、杉山直久、加納彩野、市川沙絵子、小杉浩史、岩田洋介、市原正智
- Organizer
  第15回日本検査血液学会学術集会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2014-07-21
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] UVB照射ケラチノサイトは炎症性サイトカインを分泌してメラノサイトにおける癌関連GD3合成酵素遺伝子の発現を誘導する2014
- Author(s)
  古川圭子、宮田麻衣子、田島織絵、神戸真理子、市原正智、祖父江沙矢加、古川鋼一
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜 (横浜市)
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 1. 急性呼吸窮迫症候群モデルマウスを用いた分子状水素の炎症軽減効果の検討2013
- Author(s)
  祖父江沙矢加
- Organizer
  第3回分子状水素医学シンポジウム
- Place of Presentation
  東京都品川区
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 急性呼吸窮迫症候群モデルマウスを用いた分子状水素の炎症軽減効果の検討2013
- Author(s)
  祖父江沙矢加
- Organizer
  第3回分子状水素医学シンポジウム
- Place of Presentation
  きゅりあん(東京都)
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] Molecular hydrogen alters signaling pathways and gene expression profiles in multiple mouse organs2012
- Author(s)
  Sayaka Sobue
- Organizer
  ASCB 2012
- Place of Presentation
  San Francisco(CA, USA)
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 2. Molecular hydrogen alters signaling pathways and gene expression profiles in multiple mouse organs2012
- Author(s)
  Sayaka Sobue
- Organizer
  ASCB 2012
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 分子状水素のマウス肝臓における遺伝子発現とシグナル伝達への影響2012
- Author(s)
  祖父江沙矢加
- Organizer
  第2回分子状水素医学シンポジウム
- Place of Presentation
  北里大学白金キャンパス薬学部コンベンションホール(東京都)
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 分子状水素のマウス肝臓における遺伝子発現とシグナル伝達への影響2012
- Author(s)
  祖父江沙矢加
- Organizer
  第2回分子状水素医学シンポジウム
- Place of Presentation
  北里大学白金キャンパス薬学部コンベンションホール(東京都)
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] Egr-1によるCD109遺伝子の発現制御機構の解析2012
- Author(s)
  祖父江沙矢加
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Egr-1 によるCD109 遺伝子の発現制御機構の解析2012
- Author(s)
  祖父江沙矢加
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] Molecular hydrogen attenuates ERK and p38 MAPK-pathways and alters gene expressions in mouse liver and other organs2011
- Author(s)
  Sayaka Sobue
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 分子状水素投与による肝保護効果の検討2011
- Author(s)
  Sayaka Sobue
- Organizer
  分子状水素医学シンポジウム
- Place of Presentation
  名古屋大学医学部附属病院(愛知県)
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 分子状水素投与による肝保護効果の検討2011
- Author(s)
  Sayaka Sobue
- Organizer
  分子状水素医学シンポジウム
- Place of Presentation
  名古屋大学医学部附属病院(愛知県)
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 分子状水素投与に伴う肝臓内遺伝子発現変動の解析2011
- Author(s)
  祖父江沙矢加
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] cereulide毒素による肝障害に対する分子状水素の肝保護効果の検討2010
- Author(s)
  Sayaka Sobue
- Organizer
  BMB2010
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] v-SrcによるSPHK1 mRNA安定化と発現増強2008
- Author(s)
  祖父江沙矢加
- Organizer
  第81回日本生化学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-20890251
[Presentation] v-SrcによるSPHK1 mRNA安定化と発現増強2008
- Author(s)
  祖父江沙矢加
- Organizer
  第81回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20890251
[Presentation] UVB照射ケラチノサイトは炎症性サイトカインを分泌してメラノサイトにおける癌関連GD3合成酵素遺伝子の発現を誘導する
- Author(s)
  古川圭子、宮田麻衣子、田島織絵、神戸真理子、市原正智、祖父江沙矢加、古川鋼一
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factorα and interleukin 6
- Author(s)
  Keiko Furukawa, Maiko Miyata, Masatoshi Ichihara, Orie Tajima, Sayaka Sobue, Mariko Kambe, Kazumitsu Sugiura, Koichi Furukawa
- Organizer
  9th International Symposium Glycosyltransferase
- Place of Presentation
  Porto, Portugal
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-26870682
[Presentation] 線虫を用いた分子状水素の紫外線に対する生体保護効果の検討
- Author(s)
  祖父江沙矢加
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場 (神戸市)
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6
- Author(s)
  Keiko Furukawa, Maiko Miyata, Masatoshi Ichihara, Orie Tajima, Sayaka Sobue, Mariko Kambe, Kazumitsu Sugiura, Koichi Furukawa
- Organizer
  9th International Symposium Glycosyltransferase (Glyco-T 2014)
- Place of Presentation
  Porto (Portugal)
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Egr-1によるCD109遺伝子の発現制御機構の解析
- Author(s)
  祖父江沙矢加
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 水素ガスおよび水素水の併用療法の検討
- Author(s)
  祖父江沙矢加
- Organizer
  第4回分子状水素医学シンポジウム
- Place of Presentation
  きゅりあん　(東京都品川区)
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Molecular hydrogen alters signaling pathways and gene expression profiles in multiple mouse organs.
- Author(s)
  Sobue S
- Organizer
  ASCB 2012
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-22790532
[Presentation] 急性呼吸窮迫症候群モデルマウスを用いた分子状水素の炎症軽減効果の検討
- Author(s)
  祖父江沙矢加
- Organizer
  第3回分子状水素医学シンポジウム
- Place of Presentation
  きゅりあん（東京）
- Data Source
  KAKENHI-PROJECT-22790532

1. ICHIHARA Masatoshi (00314013)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. MURAKUMO Yoshiki (40324438)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. IWAMOTO Takashi (60223426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 後藤亜由美 (20780969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 三井伸二 (80646505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MIKAKO Ito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 鈴木元

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 村手隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

SOBUE SAYAKA 祖父江 沙矢加

SOBUE Sayaka 祖父江 沙矢加

Research Projects

Research Products

Co-Researchers

筋肉の萎縮が核－細胞質輸送因子の変異によって誘導される機構の解明Principal Investigator

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胸腺腫発症ラットの原因遺伝子変異導入マウスを用いたヒトB型胸腺腫の病態解明

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Pathophysiological analysis of animal models of disease with the goal of establishing animal models of sarcopeniaPrincipal Investigator

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Identification and functional analysis of causative genes for thymoma and muscle atrophy developing in BUF/Mna rats

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Molecular hydrogen control the disease state of nonalcoholic steatohepatitis and prevent cancer by modifying gene expression by influencing the epigenetic mechanism of histone methylation modificationPrincipal Investigator

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Molecular hydrogen attenuates UV-induced tissue injury in Caenorhabditis elegans and mouse

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Elucidation of CD109 function and its tumor promotion using transgenic mice overexpressing CD109Principal Investigator

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HMBA-induced erythroid differentiation decreases sphingosine kinase 1 gene expression of a mouse erythroleukemia cell linePrincipal Investigator

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[Journal Article] Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles - Meta-analyses of gene expression profiles2018

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DOI

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[Journal Article] Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response2017

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[Journal Article] Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel2016

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[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016

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NAID

Data Source

[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016

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NAID

Data Source

[Journal Article] Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR2016

Author(s)

SOBUE SAYAKA 祖父江沙矢加

SOBUE Sayaka 祖父江沙矢加