KOSUGI Sakurako 小杉桜子

Researcher Number	50517810
Other IDs
Affiliation *help	2016 – 2018 : 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員(移行) 2011 – 2013 : 金沢大学, 医学系, 博士研究員 2010 : 金沢大学, 医学系, 研究員
Review Section/Research Field	Principal Investigator Psychiatric science
Keywords	Principal Investigator 大うつ病 / 意思決定 / 腹側被蓋野 / 個体差 / うつ病 / グルタチオン化 / 側坐核 / SSRI / redox反応 / 薬物依存 … More

Research Projects
(2results)
Research Products
(27results)

Molecular mechanisms underlying augmentation therapy with aripiprazole for major depressionPrincipal Investigator
- Principal Investigator
  
  KOSUGI Sakurako
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Kanazawa University
Attempt of developing a technique for detecting in situ protein. glutathionylation and its adaptation to the studies of psychiatric disorders.Principal Investigator
- Principal Investigator
  
  KOSUGI Sakurako
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Kanazawa University

All 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] The role of protein L-isoaspartyl/D-aspartyl O-methyltransferase (PIMT) in intracellular signal transduction.2010
- Author(s)
  Furuichi T, Kosugi S, Katane M, Sekine M, Homma H
- Journal Title
  
  Chem Biodivers
  
  Volume : Vol.7 Pages : 1337-1348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Effect of repeated oxidative stress administration on cocaine-induced sensitization and glutathione homeostasis in the rat striatal subregions2014
- Author(s)
  Y Iguchi, S Kosugi, Z Lin, Y Minabe, S Toda
- Organizer
  新学術領域「マイクロ精神病態」班会議, 若手研究交流会
- Place of Presentation
  磯辺ガーデン, 群馬
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Dissociable effects of a glutathione synthesis inhibitor on locomotor activity and stereotypy of cocaine sensitization.2013
- Author(s)
  Shigenobu Toda, Sakurako Kosugi, Yoshio Iguchi and Yoshio Minabe
- Organizer
  日本神経科学学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] マイルドな酸化ストレスがラット線条体が関与する意思決定およびコカイン誘発性行動に与える影響2013
- Author(s)
  戸田重誠、小杉桜子、井口善生、林　子喬、三邉義雄
- Organizer
  平成２５年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Temporal and persistent effects of mild oxidative stress on motivational and cognitive functions in adult rats.2013
- Author(s)
  Shigenobu Toda, Yoshio Iguchi, Sakurako Kosugi, Ziqiao Lin, and Yoshio Minabe
- Organizer
  Annual meeting of Society for Neuroscience
- Place of Presentation
  コンベンションセンター、San Diego, USA
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Individual differences in instrumental performance in naïve rats predict different responses to chronic stress2013
- Author(s)
  Y Iguchi, S Kosugi, Y Minabe, S Toda
- Organizer
  日本神経科学学会大会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Temporal and persistent effects of mild oxidative stress on motivational and cognitive functions in adult rats2013
- Author(s)
  S Toda, Y Iguchi, S Kosugi, Z Lin, Y Minabe
- Organizer
  Annual meeting of Society for Neuroscience
- Place of Presentation
  コンベンションセンター, San Diego, USA
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Individual differences in pre-stress state predict responses to chronic unpredictable stress in rats2013
- Author(s)
  Y Iguchi, S Kosugi, Y Minabe, S Toda
- Organizer
  Annual meeting of Society for Neuroscience
- Place of Presentation
  コンベンションセンター, San Diego, USA
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Individual differences in instrumental performance in naïve rats predicdifferent responses to chronic stress.2013
- Author(s)
  Yoshio Iguchi, Sakurako Kosugi, Yoshio Minabe, and Shigenobu Toda
- Organizer
  日本神経科学学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] 急性あるいは慢性のマイルドな酸化ストレスがラットの道具学習, 脱価値化, 及びコカイン誘発性行動感作に与える影響2013
- Author(s)
  S Toda, S Kosugi, Y Iguchi, Y Minabe
- Organizer
  新学術領域「マイクロ精神病態」班会議
- Place of Presentation
  名古屋ガーデンパレス
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Dissociable effect of a glutathione synthesis inhibitor on locomotor activity and stereotypy of cocaine sensitization2013
- Author(s)
  Toda, S Kosugi, Y Iguchi, Y Minabe
- Organizer
  日本神経科学学会大会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] マイルドな酸化ストレスがラット線条体が関与する意思決定およびコカイン誘発性行動に与える影響2013
- Author(s)
  戸田重誠, 小杉桜子, 井口善生, 林子喬, 三邉義雄
- Organizer
  平成25年度アルコール薬物依存関連学会合同学術総会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Individual differences in the performance of an instrumental behavior of naïve rats predict distinctive responses to chronic unpredictable stress2013
- Author(s)
  Y Iguchi, S Kosugi, Y Minabe, S Toda
- Organizer
  新学術領域「マイクロ精神病態」班会議
- Place of Presentation
  名古屋ガーデンパレス
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Cocaine Differently Affects Redox Status in the Rat Nucleus Accumbens and Dorsal Striatum2012
- Author(s)
  Yoshio Iguchi, Sakurako Kosugi, Yoshio Minabe and Shigenobu Toda
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Cocaine differently affects redox status in the rat nucleus accumbens and dorsal striatum2012
- Author(s)
  Y Iguchi, S Kosugi, Y Minabe, S Toda
- Organizer
  日本神経科学学会大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24791208
[Presentation] Glutamate-independent effects of N-acetylcysteine in synaptic protein turnover in the rat nucleus accumbens after repeated cocaine administration2011
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, Yoshio Minabe, Shigenobu Toda
- Organizer
  The 34th annual meeting of the Japan neuroscience society
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Dopamine antagonist induced-PSD protein reductions in the rat nucleus accumbens of after repeated cocaine administration2011
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, Yoshio Minabe, Shigenobu Toda
- Organizer
  第32回内藤コンファレンス「こころの機能と疾患の分子機構」
- Place of Presentation
  八ヶ岳ロイヤルホテル、山梨県
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Glutamate-independent effects of N-acetylcysteine in synaptic protein turnover in the rat nucleus accumbens after repeated cocaine administration2011
- Author(s)
  Kosugi, S., Iguchi, Y., Minabe, Y., Toda, S.
- Organizer
  Neuroscience 2011 (SfN's 41th annual meeting)
- Place of Presentation
  Convention Center, DC, USA
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Shigenobu Toda Differential subcellular localization of GluR1 and GluR2 in the nucleusaccumbens after repeated cocaineadministration ; implications for the role ofglutamatergic tone in protein turnover2011
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, TetsuHirosawa, Yoshio Minabe
- Organizer
  Neuroscience 2011(SfN's 40th annual meetin)
- Place of Presentation
  Convention center, San Diego, USA
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Differential subcellular localization ofGluR1 and GluR2 in the nucleusaccumbens after repeated cocaineadminstration ; implications for the role ofglutamatergic tone in protein turnover2011
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, TetsuHirosawa, Yoshio Minabe, ShigenobuToda.
- Organizer
  Molecular and cellular cognitive society
- Place of Presentation
  Convention center, San Diego, USA
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Glutamate-independent effects of N-acetylcysteine in synaptic protein turnover in therat nucleus accumbens after repeated cocaine administration2011
- Author(s)
  Kosugi, S., Iguchi, Y., Minabe, Y., & Toda, S
- Organizer
  Neuroscience 2011(SfN's 41thannual meeting)
- Place of Presentation
  Convention center, DC, USA
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Subcellualr localization of GluR1 and GluR2 and their regulatory factors in the nucleus accumbens of repeatedly cocaine-administrated rats ; implications for the role of glutamatergic tone in synaptic protein degradation.2010
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, Yoshio Minabe, Shigenobu Toda
- Organizer
  第33回日本神経科学学会
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Differential subcellular localization of GluR1 and GluR2 in the nucleus accumbens after repeated cocaine administration ; implications for the role of glutamatergic tone in protein turnover.2010
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, Tetsu Hirosawa, Yoshio Minabe, Shigenobu Toda
- Organizer
  Annual meeting of society for neuroscience
- Place of Presentation
  サンディエゴコンベンションセンター(米国)
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Role of PSD structure sustained by action and dopamine in the rat nucleus accumbens after repeated cocaine administration.2010
- Author(s)
  Shigenobu Toda, Sakurako Kosugi, Haowei Shen, Yoshio Iguchi, Tetsu Hirosawa, Yoshio Minabe, Peter W Kalivas
- Organizer
  Annual meeting of society for neuroscience
- Place of Presentation
  サンディエゴコンベンションセンター(米国)
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Role of PSD structure sustained by action and tonic dopamine in the rat nucleus accumbens of repeatedly cocaine-administrated rats.2010
- Author(s)
  Shigenobu Toda, Sakurako Kosugi, Haowei Shen, Yoshio Iguchi, Tetsu Hirosawa, Yoshio Minabe, Peter W Kalivas
- Organizer
  第33回日本神経科学学会
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Differential subcellular localization of GluR1 and GluR2 in the nucleus accumbens after repeated cocaine adminstration ; implications for the role of glutamatergic tone in protein turnover.2010
- Author(s)
  Sakurako Kosugi, Yoshio Iguchi, Tetsu Hirosawa, Yoshio Minabe, Shigenobu Toda
- Organizer
  Molecular and cellular cognitive society
- Place of Presentation
  サンディエゴコンベンションセンター(米国)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-22791114
[Presentation] Cocaine-induced metaplasticity may be based on the altered balance between protein trasnlation and protein elimination in the rat nucleus accumbens ; implications of glutamatergic tone for protein turnover.2010
- Author(s)
  Shigenobu Toda, Sakurako Kosugi, Haowei Shen, Yoshio Iguchi, Tetsu Hirosawa, Yoshio Minabe, Peter W Kalivas
- Organizer
  Aquitaine conference on neuroscience 2010
- Place of Presentation
  Canseil regional d'Aquitaine (France)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22791114

KOSUGI Sakurako 小杉 桜子

Research Projects

Research Products

Molecular mechanisms underlying augmentation therapy with aripiprazole for major depressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Attempt of developing a technique for detecting in situ protein. glutathionylation and its adaptation to the studies of psychiatric disorders.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The role of protein L-isoaspartyl/D-aspartyl O-methyltransferase (PIMT) in intracellular signal transduction.2010

Author(s)

Journal Title

Data Source

[Presentation] Effect of repeated oxidative stress administration on cocaine-induced sensitization and glutathione homeostasis in the rat striatal subregions2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Dissociable effects of a glutathione synthesis inhibitor on locomotor activity and stereotypy of cocaine sensitization.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] マイルドな酸化ストレスがラット線条体が関与する意思決定およびコカイン誘 発性行動に与える影響2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Temporal and persistent effects of mild oxidative stress on motivational and cognitive functions in adult rats.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Individual differences in instrumental performance in naïve rats predict different responses to chronic stress2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Temporal and persistent effects of mild oxidative stress on motivational and cognitive functions in adult rats2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Individual differences in pre-stress state predict responses to chronic unpredictable stress in rats2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Individual differences in instrumental performance in naïve rats predicdifferent responses to chronic stress.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 急性あるいは慢性のマイルドな酸化ストレスがラットの道具学習, 脱価値化, 及びコカイン誘発性行動感作に与える影響2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Dissociable effect of a glutathione synthesis inhibitor on locomotor activity and stereotypy of cocaine sensitization2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] マイルドな酸化ストレスがラット線条体が関与する意思決定およびコカイン誘発性行動に与える影響2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Individual differences in the performance of an instrumental behavior of naïve rats predict distinctive responses to chronic unpredictable stress2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Cocaine Differently Affects Redox Status in the Rat Nucleus Accumbens and Dorsal Striatum2012

KOSUGI Sakurako 小杉桜子

[Presentation] マイルドな酸化ストレスがラット線条体が関与する意思決定およびコカイン誘発性行動に与える影響2013