MOTOHASHI NORIO 本橋紀夫

… Alternative Names

Motohashi Norio 本橋紀夫

本橋紀夫モトハシノリオ

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Researcher Number	50532727
Other IDs	https://orcid.org/0000-0002-8172-4339
Affiliation (Current)	2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 室長
Affiliation (based on the past Project Information) *help	2020 – 2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 室長 2021: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2019: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所遺伝子疾患治療研究部, 科研費研究員 2015 – 2019: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2009: National Center of Neurology and Psychiatry, 神経研究所遺伝子疾患治療研究部, 外来研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Sports science / Experimental pathology Except Principal Investigator Basic Section 52020:Neurology-related / Basic Section 59040:Nutrition science and health science-related / Applied health science
Keywords	Principal Investigator 筋萎縮 / 骨格筋 / 筋疾患 / 代謝 / 筋線維タイプ / 幹細胞 / microRNA / マイクロRNA / サルコペニア / 萎縮 … More / 加齢 / 筋幹細胞 / 老化 / 筋代謝 / 生理学 / 筋ジストロフィー / 細胞移植 / Side Population細胞 / 骨格筋再生 … More Except Principal Investigator 骨格筋 / 筋線維タイプ / 筋萎縮 / バイオマーカー / 代謝変換 / フレイル / サルコペニア / マルチオミクス / LPCAT / アシル転移酵素 / リゾリン脂質 / エクソン・スキップ / リピドミクス解析 / MyoD / 尿由来細胞 / デュシェンヌ型筋ジストロフィー / ヒト尿由来細胞 / 疾患モデルマウス / マルチオミクス解析 / 加齢性筋萎縮 / 筋ジストロフィー / 運動 / サテライト細胞 / 神経筋シナプス / 代謝 / 遺伝子改変マウス / ハイブリッドファイバー / イメージング技術 / 酸化ストレス / ミトコンドリア / 代謝機能 / モデル動物 / 動物モデル / 生体内因子 / 予防 / 早期診断 / 筋線維タイプ変化 Less

筋代謝制御による筋萎縮治療の基盤創出Principal Investigator
- Principal Investigator
  
  本橋紀夫
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Center of Neurology and Psychiatry
Clarification of the mechanisms of muscle atrophy by RNA-binding proteinsPrincipal Investigator
- Principal Investigator
  
  本橋紀夫
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Center of Neurology and Psychiatry
Multi-omics technologies to reveal common mechanism of dystrophic and sarcopenic skeletal muscles
- Principal Investigator
  
  青木吉嗣
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  National Center of Neurology and Psychiatry
Elucidation of pathogenesis of sarcopenia based on the plasticity of metabolism of skeletal muscle
- Principal Investigator
  
  Shigemoto Kazuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Elucidation of the mechanisms of age-related muscle atrophy and development of novel therapies for sarcopeniaPrincipal Investigator
- Principal Investigator
  
  Motohashi Norio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Center of Neurology and Psychiatry
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Elucidation of pathogenesis of sarcopenia based on the mechanism of metabolic changes of skeletal muscle
- Principal Investigator
  
  Shigemoto Kazuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Investigation of novel factors influencing muscle fiber metabolismPrincipal Investigator
- Principal Investigator
  
  Motohashi Norio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Sports science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
細胞移植治療を目指した骨格筋再生メカニズムの解析Principal Investigator
- Principal Investigator
  
  本橋紀夫
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  National Center of Neurology and Psychiatry

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2009

All Journal Article Presentation Book

[Book] 医学と薬学2022
- Author(s)
  本橋紀夫, 青木吉嗣
- Total Pages
  72
- Publisher
  自然科学社
- Data Source
  KAKENHI-PROJECT-21K11615
[Journal Article] Characterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing2024
- Author(s)
  Kunitake Katsuhiko、Motohashi Norio、Inoue Takafumi、Suzuki Yutaka、Aoki Yoshitsugu
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 2329-2329
- DOI
  10.1038/s41598-024-52530-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-23K21412
[Journal Article] Exon 44 skipping in Duchenne muscular dystrophy: NS-089/NCNP-02, a dual-targeting antisense oligonucleotide2023
- Author(s)
  Watanabe Naoki、Tone Yuichiro、Nagata Tetsuya、Masuda Satoru、Saito Takashi、Motohashi Norio、Takagaki Kazuchika、Aoki Yoshitsugu、Takeda Shin’ichi
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 34 Pages: 102034-102034
- DOI
  10.1016/j.omtn.2023.102034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11615
[Journal Article] Techniques for Injury, Cell Transplantation, and Histological Analysis in Skeletal Muscle2023
- Author(s)
  Motohashi Norio、Minegishi Katsura、Imamura Michihiro、Aoki Yoshitsugu
- Journal Title
  
  Methods in molecular biology (Clifton, N.J.)
  
  Volume: 2640 Pages: 193-205
- DOI
  10.1007/978-1-0716-3036-5_14
- ISBN
  9781071630358, 9781071630365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15447, KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-23K21412
[Journal Article] Systemic administration of the antisense oligonucleotide <scp>NS</scp>‐089/<scp>NCNP</scp>‐02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: Study protocol for a phase I/<scp>II</scp> clinical trial2023
- Author(s)
  Ishizuka Takami、Komaki Hirofumi、Asahina Yasuko、Nakamura Harumasa、Motohashi Norio、Takeshita Eri、Shimizu‐Motohashi Yuko、Ishiyama Akihiko、Yonee Chihiro、Maruyama Shinsuke、Hida Eisuke、Aoki Yoshitsugu
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 43 Issue: 2 Pages: 277-286
- DOI
  10.1002/npr2.12335
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-21K11784
[Journal Article] Inherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein2023
- Author(s)
  Motohashi Norio、Minegishi Katsura、Aoki Yoshitsugu
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 10 Pages: 689-689
- DOI
  10.1038/s41419-023-06192-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-23K21412
[Journal Article] High‐intensity interval training in the form of isometric contraction improves fatigue resistance in dystrophin‐deficient muscle2023
- Author(s)
  Yamauchi Nao、Tamai Katsuyuki、Kimura Iori、Naito Azuma、Tokuda Nao、Ashida Yuki、Motohashi Norio、Aoki Yoshitsugu、Yamada Takashi
- Journal Title
  
  The Journal of Physiology
  
  Volume: 601 Issue: 14 Pages: 2917-2933
- DOI
  10.1113/jp284532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-21K19723, KAKENHI-PROJECT-23K21412, KAKENHI-PROJECT-23K21587
[Journal Article] Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle2022
- Author(s)
  Valentine William J.、Mostafa Sherif A.、Tokuoka Suzumi M.、Hamano Fumie、Inagaki Natsuko F.、Nordin Joel Z.、Motohashi Norio、Kita Yoshihiro、Aoki Yoshitsugu、Shimizu Takao、Shindou Hideo
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 12 Pages: 698166-698166
- DOI
  10.3389/fphys.2021.698166
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-22K08788, KAKENHI-PROJECT-23K21412
[Journal Article] Caveolin-3 regulates the activity of Ca<sup>2+</sup>/calmodulin-dependent protein kinase II in C2C12 cells2022
- Author(s)
  Matsunobe Michio、Motohashi Norio、Aoki Eito、Tominari Tsukasa、Inada Masaki、Aoki Yoshitsugu
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 323 Issue: 4 Pages: C1137-C1148
- DOI
  10.1152/ajpcell.00077.2022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-22K05490, KAKENHI-PROJECT-20H00574, KAKENHI-PROJECT-20H02534, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-23K21412, KAKENHI-PROJECT-23K24722
[Journal Article] Development of Therapeutic RNA Manipulation for Muscular Dystrophy2022
- Author(s)
  Saifullah, Norio Motohashi, Toshifumi Tsukahara, Yoshitsugu Aoki
- Journal Title
  
  Front Genome Ed
  
  Volume: 4 Pages: 863651-863651
- DOI
  10.3389/fgeed.2022.863651
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-22KF0410, KAKENHI-PROJECT-21H02067
[Journal Article] Quantitative Evaluation of Exon Skipping in Urine-Derived Cells for Duchenne Muscular Dystrophy2022
- Author(s)
  Kunitake Katsuhiko、Sathyaprakash Chaitra、Motohashi Norio、Aoki Yoshitsugu
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2587 Pages: 153-164
- DOI
  10.1007/978-1-0716-2772-3_9
- ISBN
  9781071627716, 9781071627723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11615
[Journal Article] Translational research for neuromuscular diseases2022
- Author(s)
  本橋紀夫、青木吉嗣
- Journal Title
  
  Neurological Therapeutics
  
  Volume: 39 Issue: 4 Pages: 430-434
- DOI
  10.15082/jsnt.39.4_430
- NAID
  130008102587
- ISSN
  0916-8443, 2189-7824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21K11615
[Journal Article] Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient <i>mdx</i> mice2021
- Author(s)
  Nogami Ken'ichiro、Maruyama Yusuke、Sakai-Takemura Fusako、Motohashi Norio、Elhussieny Ahmed、Imamura Michihiro、Miyashita Satoshi、Ogawa Megumu、Noguchi Satoru、Tamura Yuki、Kira Jun-ichi、Aoki Yoshitsugu、Takeda Shin'ichi、Miyagoe-Suzuki Yuko
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 30 Issue: 11 Pages: 1006-1019
- DOI
  10.1093/hmg/ddab100
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02067, KAKENHI-PROJECT-21K11615, KAKENHI-PROJECT-20K15919, KAKENHI-PROJECT-19K07519
[Journal Article] Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping2020
- Author(s)
  Hara Yuko、Mizobe Yoshitaka、Inoue Yukiko U.、Hashimoto Yasumasa、Motohashi Norio、Masaki Yoshiaki、Seio Kohji、Takeda Shin’ichi、Nagata Tetsuya、Wood Matthew J. A.、Inoue Takayoshi、Aoki Yoshitsugu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 10110-10110
- DOI
  10.1038/s41598-020-67077-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-18K07544, KAKENHI-PROJECT-18K11067
[Journal Article] Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy2020
- Author(s)
  van Westering Tirsa L.E.、Johansson Henrik J.、Hanson Britt、Coenen-Stass Anna M.L.、Lomonosova Yulia、Tanihata Jun、Motohashi Norio、Yokota Toshifumi、Takeda Shin'ichi、Lehti? Janne、Wood Matthew J.A.、EL Andaloussi Samir、Aoki Yoshitsugu、Roberts Thomas C.
- Journal Title
  
  Molecular & Cellular Proteomics
  
  Volume: 19 Issue: 12 Pages: 2047-2068
- DOI
  10.1074/mcp.ra120.002345
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09511, KAKENHI-PROJECT-18K07544, KAKENHI-PROJECT-18K11067
[Journal Article] An inducible knockout of Dicer in adult mice does not affect endurance exercise-induced muscle adaptation2019
- Author(s)
  Oikawa Satoshi、Lee Minjung、Motohashi Norio、Maeda Seiji、Akimoto Takayuki
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 316 Issue: 2 Pages: C285-C292
- DOI
  10.1152/ajpcell.00278.2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11067
[Journal Article] Potential Therapies Using Myogenic Stem Cells Combined with Bio-Engineering Approaches for Treatment of Muscular Dystrophies2019
- Author(s)
  Motohashi Norio、Shimizu-Motohash Yuko、Roberts Thomas、Aoki Yoshitsugu
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 9 Pages: 1066-1066
- DOI
  10.3390/cells8091066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07544, KAKENHI-PROJECT-18K11067
[Journal Article] Restoring Dystrophin Expression in Duchenne Muscular Dystrophy: Current Status of Therapeutic Approaches2019
- Author(s)
  Shimizu-Motohashi Yuko、Komaki Hirofumi、Motohashi Norio、Takeda Shin’ichi、Yokota Toshifumi、Aoki Yoshitsugu
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 9 Issue: 1 Pages: 1-1
- DOI
  10.3390/jpm9010001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07544, KAKENHI-PROJECT-18K11067
[Journal Article] サルコペニア・フレイルのメカニズムと脳卒中.2018
- Author(s)
  重本和宏, 森秀一, 本橋紀夫, 高嶋留美
- Journal Title
  
  分子脳血管病
  
  Volume: 17 Pages: 119-122
- Data Source
  KAKENHI-PROJECT-16H03266
[Journal Article] Tbx1 regulates inherited metabolic and myogenic abilities of progenitor cells derived from slow- and fast-type muscle2018
- Author(s)
  Motohashi Norio、Uezumi Akiyoshi、Asakura Atsushi、Ikemoto-Uezumi Madoka、Mori Shuuichi、Mizunoe Yuhei、Takashima Rumi、Miyagoe-Suzuki Yuko、Takeda Shin’ichi、Shigemoto Kazuhiro
- Journal Title
  
  Cell Death & Differentiation
  
  Volume: 印刷中 Issue: 6 Pages: 1024-1036
- DOI
  10.1038/s41418-018-0186-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11067, KAKENHI-PROJECT-16H03266, KAKENHI-PROJECT-16K01851, KAKENHI-PROJECT-16K10881, KAKENHI-PROJECT-19H04064
[Journal Article] サルコペニ・アフレイルの基礎研究の現状.2018
- Author(s)
  重本和宏, 森秀一, 本橋紀夫, 高嶋留美
- Journal Title
  
  日本臨床増刊号
  
  Volume: 上 Pages: 189-193
- Data Source
  KAKENHI-PROJECT-16H03266
[Journal Article] フレイルのバイオマーカー探索.2018
- Author(s)
  重本和宏, 森秀一, 本橋紀夫, 高嶋留美
- Journal Title
  
  最新医学別冊
  
  Volume: 別冊 Pages: 67-73
- Data Source
  KAKENHI-PROJECT-16H03266
[Journal Article] サルコペニアの概念とその診断方法.2018
- Author(s)
  重本和宏, 森秀一, 本橋紀夫, 高嶋留美
- Journal Title
  
  臨床と病理
  
  Volume: 136 Pages: 128-134
- Data Source
  KAKENHI-PROJECT-16H03266
[Journal Article] Immunization of mice with LRP4 induces myasthenia similar to MuSK-associated myasthenia gravis.2017
- Author(s)
  Mori S, Motohashi N, Takashima R, Kishi M, Nishimune H, Shigemoto K.
- Journal Title
  
  Experimental Neurology
  
  Volume: 297 Pages: 158-167
- DOI
  10.1016/j.expneurol.2017.08.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01851, KAKENHI-PROJECT-16H03266, KAKENHI-PROJECT-15H05364
[Journal Article] サルコペニア発症における神経経の関与2016
- Author(s)
  重本和宏、森秀一,　本橋紀夫
- Journal Title
  
  最新醫學別冊　診断と治療のABC112
  
  Volume: 診断と治療のABC112 Pages: 40-46
- Data Source
  KAKENHI-PROJECT-16H03266
[Journal Article] 「筋サテライト細胞除去と骨格筋量に関する論文の考察」－筋サテライト細胞の新たな可能性を探る－2016
- Author(s)
  本橋紀夫
- Journal Title
  
  基礎老化研究
  
  Volume: 40 Pages: 41-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05364
[Journal Article] Stem Cell Differentiation and Therapeutic Use: Progress towards the Clinic2015
- Author(s)
  Alexander MS, Casar JC, Motohashi N
- Journal Title
  
  Stem Cells International
  
  Volume: 2015 Pages: 308128-308128
- DOI
  10.1155/2015/308128
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05364
[Journal Article] Metabolic plasticity in sarcopenia.2015
- Author(s)
  Shigemoto K, Motohashi N, Mori S
- Journal Title
  
  J Phys Fitness Sports Med
  
  Volume: 4 Pages: 347-350
- NAID
  130005113194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05364
[Journal Article] Generation of transplantable, functional satellite-like cells from mouse embryonic stem cells2009
- Author(s)
  Chang H, Yoshimoto M, Umeda K, Iwasa T, Mizuno Y, Fukada S, Yamamoto H, Motohashi N, Miyagce-Suzuki Y, Takeda S, Heike T, Nakahata T.
- Journal Title
  
  FASEB Journal 23
  
  Pages: 1907-1919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790399
[Presentation] RNA 結合タンパク質を介した筋代謝制御2024
- Author(s)
  本橋紀夫
- Organizer
  第10 回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] 筋脂質代謝と筋疾患との関連2024
- Author(s)
  本橋紀夫, 芦田雪, Saifullah, 青木吉嗣
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] 筋代謝制御による筋ジストロフィーの治療戦略2023
- Author(s)
  本橋紀夫
- Organizer
  第16回筋ジストロフィー治療研究会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] 筋代謝制御による核酸医薬デリバリー効率改善の試み2023
- Author(s)
  本橋紀夫, 青木吉嗣
- Organizer
  第41回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] 筋代謝制御による筋ジストロフィーの新しい治療戦略2023
- Author(s)
  本橋紀夫, Saifullah, 芦田雪, 寺田玲子, 大久保陽子, 青木吉嗣
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] Clarification of functional differences in satellite cells from different fiber types2022
- Author(s)
  Norio Motohashi
- Organizer
  12th Japanese-French Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] RNA結合タンパク質によるDMDマウスの代謝制御2022
- Author(s)
  本橋紀夫, Saifullah, 寺田玲子, 大久保陽子, 青木吉嗣
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] ミトコンドリアによって制御される筋幹細胞の自己複製機構とサルコペニアへの影響2022
- Author(s)
  本橋紀夫
- Organizer
  第9 回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] Macrophage scavenger receptor 1-deficiency reduces fibrosis in cardiac muscles of dystrophy model mice,2022
- Author(s)
  Norio Motohashi, Yoshitaka Mizobe, Shouta Miyatake, Koichi Kimura, Yuko Hara, Maria K. Tsoumpra, Hotake Takizawa, Shin’ichi Takeda, Yoshitsugu Aoki
- Organizer
  Myology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] RNA結合タンパク質による筋代謝制御2022
- Author(s)
  本橋紀夫, Saifullah, 寺田玲子, 大久保陽子, 青木吉嗣
- Organizer
  第15回筋ジストロフィー治療研究会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] ミトコンドリアによって制御される筋幹細胞の自己複製機構とサルコペニアへの影響2022
- Author(s)
  本橋紀夫, 峰岸かつら, 青木吉嗣
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] プロスタグランジンE2受容体EP2は骨格筋幹細胞の維持に重要である2021
- Author(s)
  丸山友輔, 丸山友輔, 野上健一郎, 本橋紀夫, 竹村英子, 青木吉嗣, 内海文彰, 鈴木友子
- Organizer
  第７回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] Caveolin-3発現が骨格筋細胞に与える影響2021
- Author(s)
  松延道生, 本橋紀夫, 稲田全規, 宮浦千里, 青木吉嗣
- Organizer
  第７回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] マクロファージを介した筋再生ネットワークと筋疾患2021
- Author(s)
  本橋紀夫
- Organizer
  第７回日本筋学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] DMDモデルマウスにおけるCa2+依存性STAC3の分解2021
- Author(s)
  芦田雪, 芦田雪, 檜森弘一, 檜森弘一, 竹中菜々, 本橋紀夫, 青木吉嗣, 櫻井英俊, 山田崇史
- Organizer
  第７回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] シングルセル解析に基づくヒト尿における筋疾患モデル化に有用な細胞集団の特定2021
- Author(s)
  邦武克彦, 本橋紀夫, 鈴木穣, 青木吉嗣
- Organizer
  第７回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] 等尺性収縮トレーニングはDMDモデルマウスの筋持久力を改善する2021
- Author(s)
  山内菜緒, 木村伊織, 内藤雷, 芦田雪, 芦田雪, 徳田奈央, 本橋紀夫, 青木吉嗣, 山田崇史
- Organizer
  第７回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11615
[Presentation] 部位特異的な筋幹細胞に着目した骨格筋維持機構の解明2020
- Author(s)
  本橋紀夫, 津元裕樹, 三浦ゆり, 峰岸かつら, 青木吉嗣
- Organizer
  精神・神経疾患研究開発費筋ジストロフィー研究班合同班会議
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] マクロファージスカベンジャー受容体（SR-A1）欠損による骨格筋・心筋への影響2020
- Author(s)
  本橋紀夫, 青木吉嗣, 溝部吉高, 宮武正太, 木村公一, 原裕子, Maria K Tsoumpra, 滝澤歩武
- Organizer
  精神・神経疾患研究開発費「疾患モデル動物を基盤とした筋ジストロフィーの新しい治療法開発」班, 令和２年度班会議
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] 部位特異的な筋幹細胞に着目した骨格筋維持機構の解明2020
- Author(s)
  本橋紀夫, 津元裕樹, 三浦ゆり, 峰岸かつら, 青木吉嗣
- Organizer
  精神・神経疾患研究開発費「筋ジストロフィー関連疾患の分子病態解明とそれに基づく診断法・治療法開発」班, 令和２年度班会議
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] 筋線維タイプで異なる筋衛星細胞の機能特性2019
- Author(s)
  本橋紀夫
- Organizer
  第5回日本筋学会
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] 筋線維タイプで異なる筋衛星細胞の機能特性2019
- Author(s)
  本橋紀夫
- Organizer
  第７回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] 筋線維タイプから見る筋衛星細胞の機能2019
- Author(s)
  本橋紀夫
- Organizer
  第74回日本体力医学会大会シンポジウム「骨格筋の修復・再生システムの分子細胞基盤」
- Invited
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] 遺伝子治療開発を目的とした骨格筋部位特異的な筋衛星細胞の基盤研究2019
- Author(s)
  本橋紀夫
- Organizer
  精神・神経疾患研究開発費「ジストロフィン欠損モデル動物を基盤とした筋ジストロフィーの新しい治療法開発」班研究班会議
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] Serum protein derived from skeletal muscle is a candidate biomarker for neuromuscular communication.2019
- Author(s)
  Mori S, Motohashi N, Takashima R, Shigemoto K.
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19H04064
[Presentation] 細胞移植治療を目指した筋幹細胞の基盤研究-筋線維タイプに着目して-2019
- Author(s)
  本橋紀夫
- Organizer
  第１４回筋ジストロフィー研究会
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] Development of screening system for identification of novel factors influencing muscle fiber types2018
- Author(s)
  Norio Motohashi, Shuuichi Mori, Rumi Takashima and Kazuhiro Shigemoto
- Organizer
  Molecular mechanisms of muscle wasting during aging and disease, Ascona, Switzerland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] Development of screening system for identification of novel factors influencing muscle fiber types2018
- Author(s)
  Norio Motohashi, Shuuichi Mori, Rumi Takashima, Kazuhiro Shigemoto
- Organizer
  Molecular mechanisms of muscle wasting during aging and disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] Identification of novel molecular mediators of muscle fiber-type switch2018
- Author(s)
  Norio Motohashi, Shuuichi Mori, Rumi Takashima and Kazuhiro Shigemoto
- Organizer
  Cell Symposia:Multifaceted Mitochondria
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] 筋線維タイプを識別できるMusColorマウスの開発2018
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第４回日本筋学会
- Data Source
  KAKENHI-PROJECT-18K11067
[Presentation] 筋線維タイプを識別できるMusColorマウスの開発2018
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第４回日本筋学会, 岡山（倉敷）
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] NMJ由来タンパク質の血中バイオマーカーとしての有用性検討,2018
- Author(s)
  森秀一, 本橋紀夫, 高嶋留美, 重本和宏
- Organizer
  第73回日本体力医学会, 福井
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] 抗Lrp4抗体陽性重症筋無力症の自己免疫動物モデルの作成2017
- Author(s)
  森秀一, 本橋紀夫, 高嶋留美, 岸雅彦, 西宗裕史, 重本和宏
- Organizer
  日本神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] 筋衛星細胞と筋線維タイプの関連2017
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏
- Organizer
  首都大学東京バイオコンフェレンス2017
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 筋衛星細胞の自己複製機構と筋線維タイプ2017
- Author(s)
  本橋紀夫
- Organizer
  第５回骨格筋生物学研究会
- Place of Presentation
  東京大学駒場キャンパス（東京都目黒区）
- Year and Date
  2017-03-04
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] Lrp4の機能抑制による神経筋刺激伝達の変化2017
- Author(s)
  森秀一, 本橋紀夫, 高嶋留美, 岸雅彦, 重本和宏
- Organizer
  第７２回日本体力医学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] Identification of novel factors influencing muscle fiber type transition2017
- Author(s)
  Motohashi N, Mori S, Takashima R and Shigemoto K.
- Organizer
  2017 Keystone Symposia Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] 骨格筋代謝制御因子の同定2017
- Author(s)
  本橋紀夫, 朝倉淳, 森秀一, 高嶋留美, 上住円, 上住聡芳, 重本和宏
- Organizer
  第３回日本筋学会
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 新規骨格筋代謝制御因子の同定2017
- Author(s)
  本橋紀夫, 朝倉淳, 森秀一, 高嶋留美, 上住円, 上住聡芳, 重本和宏
- Organizer
  第５回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] Mouse Model of LRP4-MG.2017
- Author(s)
  Mori S, Motohashi N, Takashima R, Kishi M and Nishimune H and Shigemoto K
- Organizer
  13th International Conference on Myasthenia Gravis and Related Disorders conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] Identification of novel factors influencing muscle fiber type transition2017
- Author(s)
  Norio Motohashi, Shu-ichi Mori, Rumi Takashima and Kazuhiro Shigemoto
- Organizer
  2017 Keystone Symposia Conference; Aging and Mechanisms of Aging-Related Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 骨格筋代謝制御因子の同定2017
- Author(s)
  本橋紀夫, 朝倉淳, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第７２回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] Impairment of presynaptic functions and structures of NMJ in mice with Lrp4 induced myasthenia.2017
- Author(s)
  Shigemoto K, Mori S, Motohashi N, Takashima R, Kishi M and Nishimune H
- Organizer
  XXII World Congress of Neurology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] 骨格筋代謝制御因子の同定2017
- Author(s)
  本橋紀夫, 朝倉淳, 森秀一, 高嶋留美, 上住円, 上住聡芳, 重本和宏
- Organizer
  第３回日本筋学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] 筋線維タイプと骨格筋幹細胞維持機構の関連2016
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第２回日本筋学会
- Place of Presentation
  国立精神神経医療研究センター（東京都小平市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 新規筋線維タイプ変換誘導因子の探索2016
- Author(s)
  本橋紀夫, 森秀一, 山崎綾乃, 高嶋留美, 重本和宏
- Organizer
  第４回若手による骨格筋細胞研究会
- Place of Presentation
  ウインクあいち（愛知県・名古屋市）
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] microRNAによる骨格筋幹細胞の維持機構2016
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第７１回日本体力医学会大会
- Place of Presentation
  盛岡市民文化ホール（岩手県・盛岡市）
- Data Source
  KAKENHI-PROJECT-16H03266
[Presentation] microRNAによる骨格筋幹細胞の維持機構2016
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第７１回日本体力医学会大会
- Place of Presentation
  いわて県民情報交流センター（岩手県盛岡市）
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 新規筋線維タイプ変換誘導因子の探索2016
- Author(s)
  本橋紀夫, 森秀一, 山崎綾乃, 高嶋留美, 重本和宏
- Organizer
  第４回若手による骨格筋細胞研究会
- Place of Presentation
  ウィンクあいち（愛知県名古屋市）
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 骨格筋幹細胞における維持機構の解明2015
- Author(s)
  本橋紀夫, 朝倉淳, 森秀一, 高嶋留美, 重本和宏
- Organizer
  第３８回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2015-06-14
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] microRNAを介した骨格筋幹細胞維持機構2015
- Author(s)
  本橋紀夫, 森秀一, 重本和宏, 高嶋留美, 高谷智英, 朝倉淳
- Organizer
  第１回日本筋学会
- Place of Presentation
  国立研究開発法人国立精神・神経医療研究センター(東京都小平市)
- Year and Date
  2015-08-08
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 筋線維タイプと筋衛星細胞自己複製機構の関連2015
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏, 朝倉淳
- Organizer
  第７０回日本体力医学会大会
- Place of Presentation
  ホテルアバローム紀の国(和歌山県和歌山市)
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-15H05364
[Presentation] 筋線維タイプと筋衛星細胞自己複製機構の関連2015
- Author(s)
  本橋紀夫, 森秀一, 高嶋留美, 重本和宏, 朝倉淳
- Organizer
  第３回骨格筋細胞研究会
- Place of Presentation
  九州大学(福岡県福岡市)
- Year and Date
  2015-11-24
- Data Source
  KAKENHI-PROJECT-15H05364

1. Shigemoto Kazuhiro (40284400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. 森秀一 (30508677)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. 大村卓也 (40848420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 金憲経 (20282345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 青木吉嗣 (80534172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 進藤英雄 (10401027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. バレンタインウィリアム (60792900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. INOUE Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. TANIHATA Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 峰岸かつら

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MOTOHASHI NORIO 本橋 紀夫

Motohashi Norio 本橋 紀夫

本橋 紀夫 モトハシ ノリオ

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筋代謝制御による筋萎縮治療の基盤創出Principal Investigator

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Clarification of the mechanisms of muscle atrophy by RNA-binding proteinsPrincipal Investigator

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Multi-omics technologies to reveal common mechanism of dystrophic and sarcopenic skeletal muscles

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Elucidation of pathogenesis of sarcopenia based on the plasticity of metabolism of skeletal muscle

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Elucidation of the mechanisms of age-related muscle atrophy and development of novel therapies for sarcopeniaPrincipal Investigator

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Elucidation of pathogenesis of sarcopenia based on the mechanism of metabolic changes of skeletal muscle

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Investigation of novel factors influencing muscle fiber metabolismPrincipal Investigator

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細胞移植治療を目指した骨格筋再生メカニズムの解析Principal Investigator

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[Book] 医学と薬学2022

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[Journal Article] Characterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing2024

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[Journal Article] Exon 44 skipping in Duchenne muscular dystrophy: NS-089/NCNP-02, a dual-targeting antisense oligonucleotide2023

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[Journal Article] Techniques for Injury, Cell Transplantation, and Histological Analysis in Skeletal Muscle2023

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[Journal Article] Systemic administration of the antisense oligonucleotide <scp>NS</scp>‐089/<scp>NCNP</scp>‐02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: Study protocol for a phase I/<scp>II</scp> clinical trial2023

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MOTOHASHI NORIO 本橋紀夫

Motohashi Norio 本橋紀夫

本橋紀夫モトハシノリオ