NAKANO Megumi 中野めぐみ

Researcher Number	50542825
Affiliation (based on the past Project Information) *help	2015: (公益財団法人)かずさDNA研究所, 研究員 2013: (公益財団法人)かずさDNA 研究所, 研究員 2013: 公益財団法人かずさＤＮＡ研究所, 細胞工学研究室, 研究員 2012 – 2013: 公益財団法人かずさＤＮＡ研究所, ヒトゲノム研究部, 研究員 2012: 公益財団法人かずさDNA 研究所, ヒトゲノム研究部, 研究員 2011: (財)かずさＤＮＡ研究所, その他部局等, その他 2010: (財団法人)かずさDNA研究所, 研究員
Review Section/Research Field	Principal Investigator Genetics/Genome dynamics Except Principal Investigator Molecular biology / Biological Sciences / Laboratory animal science
Keywords	Principal Investigator HAC / 染色体 / ヒト人工染色体 / クロマチン / 人工染色体 / セントロメア Except Principal Investigator ヘテロクロマチン / セントロメア / ヒト人工染色体 / クロマチン … More / 人工染色体 / 染色体 / 遺伝学 / 反復DNA / Suv39h1 / Suv39H1 / CENP-B / ヒストンアセチル化酵素 / CENP-A / サテライトDNA / 非コードDNA / 遺伝子機能解析手法開発 / トランスジェニックマウス / 動物実験技術 / エピジェネティックス / 分配 Less

Analysis of mechanism involved in the assembly balance between centromere chromatin and/or heterochromatin and in higher cellular regulation.
- Principal Investigator
  
  MASUMOTO Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kazusa DNA Research Institute
Development of gene functional analysis system using human artificial chromosome in mouse
- Principal Investigator
  
  OKAMURA Yoshiaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  公益財団法人かずさDNA 研究所
   Kazusa DNA Research Institute
The construction of multi-chromatin inducible human artificial chromosome (HAC)Principal Investigator
- Principal Investigator
  
  NAKANO Megumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Kazusa DNA Research Institute
Analysis of chromatin network involving centromere functional components
- Principal Investigator
  
  Masumoto Hiroshi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kazusa DNA Research Institute
The analysis of basic chromosomal functions using human artificial chromosomes (HACs) and the development of novel HACs.
- Principal Investigator
  
  MASUMOTO Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kazusa DNA Research Institute

All 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 染色体分配装置セントロメアの形成メカニズム、蛋白質核酸酵素(54 査読無し)2009
- Author(s)
  中野めぐみ、舛本寛
- Data Source
  KAKENHI-PROJECT-20247019
[Journal Article] Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome.2014
- Author(s)
  Erliandri I, Fu H, Nakano M, Kim JH, Miga KH, Liskovykh M, Earnshaw WC, Masumoto H, Kouprina N, Aladjem MI, Larionov V
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 42(18) Issue: 18 Pages: 11502-11516
- DOI
  10.1093/nar/gku835
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23114008
[Journal Article] Breaking the HAC Barrier : Histone H3K9 acetyl/methyl balance regulates CENP-A assembly2012
- Author(s)
  Ohzeki J, Bergmann JH, Kouprina N, Noskov V, Nakano M, Kimura H, Earnshaw WC, Larionov V and Masumoto H
- Journal Title
  
  EMBO J
  
  Volume: 31(10) Pages: 2391-2402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247030
[Journal Article] Organization of Synthetic Alphoid DNA Array in Human Artifcial Chromosome (HAC) with a Conditional Centromere2012
- Author(s)
  Kouprina N, Samoshkin A, Erliandri I, Nakano M, Lee H-S, Fu H, Iida Y, Aladjem M, Oshimura M, Masumoto H, Earnshaw WC and Larionov V
- Journal Title
  
  ACS Synth.Biol.
  
  Volume: 1(12) Pages: 590-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247030
[Journal Article] Epigenetic Engineering : Histone H3K9 acetylation is compatible with kinetochore structure and function2012
- Author(s)
  Bergmann JH, Jakubsche J, Martins NM, Nakano M, Kimura H, Kelly DA, Turner BM, Masumoto H, Larionov V and Earnshaw WC
- Journal Title
  
  J. Cell Science
  
  Volume: 125(Pt 2) Pages: 411-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247030
[Journal Article] Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere2012
- Author(s)
  Kouprina N, Samoshkin A, Erliandri N, Nakano M, Lee HS, Fu H, Lida Y, Aladjem M, Oshimura M, Masumoto H, Earnshaw WC, Larionov V
- Journal Title
  
  ACS Synth Biol
  
  Volume: 1(12) Pages: 590-601
- Data Source
  KAKENHI-PROJECT-23770011
[Journal Article] Human Artificial Chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells2011
- Author(s)
  Kim J-H, Kononenko A, Erliandri I, Kim T, Nakano M, Iida Y, Barrett CJ, Oshimura M, Masumoto H, Earnshaw WC, Larionov V & Kouprina N
- Journal Title
  
  PNAS
  
  Volume: 108 Pages: 20048-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247030
[Journal Article] Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier.2009
- Author(s)
  Cardinale S., Bergmann J.H., Kelly D., Nakano M., Valdivia M.M., Kimura H., Masumoto H., Larionov V., Earnshaw W.C.
- Journal Title
  
  Mol.Biol.Cell 20
  
  Pages: 4194-4204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247019
[Journal Article] 染色体分配装置セントロメアの形成メカニズム2009
- Author(s)
  中野めぐみ
- Journal Title
  
  蛋白質核酸酵素 54 (4)
  
  Pages: 427-435
- Data Source
  KAKENHI-PROJECT-20247019
[Journal Article] 染色体分配装置セントロメアの形成メカニズム2009
- Author(s)
  中野めぐみ
- Journal Title
  
  蛋白質核酸酵素 54(4)
  
  Pages: 427-435
- Data Source
  KAKENHI-PROJECT-20247019
[Journal Article] Inactivation of a human kinetochore by specific targeting of chromatin modifiers.2008
- Author(s)
  Nakano M., Cardinale S., Noskov V.N., Gassmann R., Vagnarelli P., Kandels-Lewis S., Larionov V., Earnshaw W.C., Masumoto H.
- Journal Title
  
  Dev.Cell 14
  
  Pages: 507-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247019
[Journal Article] Inactivation of a human kinetochore by specific targeting of chromatin modifiers2008
- Author(s)
  Megumi Nakano
- Journal Title
  
  Developmental Cell 14
  
  Pages: 507-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247019
[Presentation] セントロメア形成を制御するアセチル化酵素の探索2013
- Author(s)
  大関淳一郎、庄野暢晃、大竹興一郎、中野めぐみ、William C. Earnshaw、Vladimir Larionov、長瀬隆弘、舛本　寛
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] 脱落制御可能なヒト人工染色体(HAC) を用いたiPS 細胞の作製と細胞選抜への利用2013
- Author(s)
  岡村佳明、霜島司、中野めぐみ、大関淳一郎、長谷川嘉則、池野正史、William C. Earnshaw, Vladimir Larionov、舛本寛
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PLANNED-23114008
[Presentation] セントロメア形成を制御するアセチル化酵素の探索2013
- Author(s)
  大関淳一郎、庄野暢晃、大竹興一郎、中野めぐみ、William C. Earnshaw、Vladimir Larionov、長瀬隆弘、舛本　寛
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PLANNED-23114008
[Presentation] 脱落制御可能なヒト人工染色体(HAC) を用いたiPS 細胞の作製と細胞選抜への利用2013
- Author(s)
  岡村佳明、霜島司、中野めぐみ、大関淳一郎、長谷川嘉則、池野正史、William C. Earnshaw, Vladimir Larionov、舛本寛
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] Analysis of centromere chromatin assembly using tetO/tetR synthetic DNA system2012
- Author(s)
  Shono N, Ohzeki J, Nakano M, Nagase T, Earnshaw WC, Larionov V, Masumoto H
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場(口頭発表)
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] 細胞へ導入されたDNAの運命 : 人工染色体形成、宿主染色体への組込み、核からの脱落、はどのように起こるか?2012
- Author(s)
  舛本寛、大関淳一郎、中野めぐみ、Larionov V and Earnshaw WC
- Organizer
  第84回日本遺伝学会大会
- Place of Presentation
  博多
- Invited
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] Heterochromatin assembly balance determines the fate of de novo kinetochre formation on satellite DNA(ミニシンポジウム主催)2012
- Author(s)
  Masumoto H, Ohzeki J, Nakano M, Vladimir N, Kouprina N, Earnshaw WC and Larionov V
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] Exploring of centromere acetylating mechanism using tetO-alphoid system2012
- Author(s)
  Ohzeki J, Shono N, Otake K, Nakano M, Earnshaw WC, Larionov V, Nagase T, Masumoto H
- Organizer
  第30回染色体ワークショップ、第11回核ダイナミクス研究会
- Place of Presentation
  淡路夢舞台国際会議(口頭発表)
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] The analyses of regulation and maintenance mechanisms of centromere structure with chromatin-alterable HAC system2012
- Author(s)
  Nakano M, Ohzeki J, Otake K, Shono N, Larionov V, Earnshaw WC, Masumoto H
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23770011
[Presentation] Generation of induced Pluripotent stem cells (iPSCs) using conditional human artificial chromosome (HAC)2012
- Author(s)
  Yoshiaki Okamura, Tsukasa shimojima, Megumi Nakano, Jun-ichirou Ohzeki, Yoshinori Hasegawa, Masashi Ikeno, William C. Earnshaw, Vladimir Larionov and Hiroshi Masumoto
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23700519
[Presentation] The Analysis of regulation and maintenance mechanisms of centromere functional structure with chromatin-alterable human artificial chromosome system.2012
- Author(s)
  Nakano M.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PLANNED-23114008
[Presentation] The analyses of regulation and maintenance mechanisms of centromere functional structure with chromatin-alterable human artificial chromosome system2012
- Author(s)
  Megumi Nakano, Jun-Ihirou Ohzeki, Koichiro Otake, Nobuaki Shono, Vladimir Larionov, William Earnshaw, and Hiroshi Masumoto
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23770011
[Presentation] The Analysis of regulation and maintenance mechanisms of centromere functional structure with chromatin-alterable human artificial chromosome system.2012
- Author(s)
  Nakano M.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] A chromatin assembly balance on satellite DNA determines the fate of de novo kinetochore and HAC formation2011
- Author(s)
  Masumoto H, Ohzeki J, Nakano M, Kouprina N, Larionov V and Earnshaw WC
- Organizer
  Japanese-German JSPS and DFG-funded workshop "Centromeres and Artificial Chromosomes"
- Place of Presentation
  Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] Generation of induced Pluripotent stem cells (iPSCs) using conditional human artificial chromosome (HAC)2011
- Author(s)
  Yoshiaki Okamura, Tsukasa Simojima, Megumi Nakano, Jun-ichirou Ohzeki, Yoshinori Hasegawa, Masashi Ikeno, William C. Earnshaw, Vladimir Larionov, Hiroshi Masumoto
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-23700519
[Presentation] Chromatin assembly balance determines the fate of de novo kinetochre formation on satellite DNA2011
- Author(s)
  Masumoto H, Ohzeki J, Nakano M, Kouprina N, Larionov V, Earnshaw WC
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] セントロメアをアセチル化する機構の探索2011
- Author(s)
  大関淳一郎、庄野暢晃、中野めぐみ、 William C. Earnshaw, Vladimir Larionov、長瀬隆弘、舛本寛
- Organizer
  第29回染色体ワークショップ
- Place of Presentation
  仙台(口頭)
- Data Source
  KAKENHI-PROJECT-23247030
[Presentation] Analyses of DNA elements and chromatin structures required for the efficient formation of human artificialchromosome2011
- Author(s)
  Megumi Nakano, Jun-Ichirou Ohzeki, Yoshiaki Okamura, Tsukasa Shimojima, Masashi Ikeno, Vladimir Larionov, William Earnshaw, Hiroshi Masumoto
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23770011
[Presentation] A chromatin assembly balance determines the fate of de novo kinetochre or heterochromatin formation on satellite DNA.2010
- Author(s)
  Masumoto H., Ohzeki J., Nakano M., et al. V.
- Organizer
  EMBO Workshop on Chromosome Segregation and Aneuploidy
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-20247019
[Presentation] Dynamic Assembly mechanism of Centromere Chromatin and Heterochromatin on Human Satellite DNA.2009
- Author(s)
  Masumoto H., Ohzeki J., Nakano M., Okada T., Larionov V., Earnshaw W.C.
- Organizer
  The 24^<th> Naito Conference on "Nuclear Dynamics and RNA [II]"
- Place of Presentation
  Sapporo
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20247019
[Presentation] セントロメア機能形成に関わるダイナミックなクロマチン集合バランス2008
- Author(s)
  舛本寛、中野めぐみ、大関淳一郎、他
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20247019
[Presentation] クロマチン制御によるde novoヒト人工染色体形成最適化の試み
- Author(s)
  岡崎孝映、中野めぐみ、大関淳一郎、大竹興一郎、庄野暢晃、山田和子、Larinov　V、Earnshaw WC、舛本寛
- Organizer
  第３７回日本分子生物学会年会（ポスター発表）
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PLANNED-23114008
[Presentation] Role of hMis18 complex-associating HAT protein for new CENP-A assembly.
- Author(s)
  Ohzeki J, Shono N, Otake K, Nakano M, Kimura H, Earnshaw WC, Larionov V, Nagase T, Masumoto H
- Organizer
  第３7回日本分子生物学会年会（ポスター発表）
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PLANNED-23114008

1. OHZEKI Jun-Ichirou (30514088)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. MASUMOTO Hiroshi (70229384)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
3. OKAMURA Yoshiaki (90569831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. OKAZAKI Kouei (70213923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KUGOU Kazuto (60554425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKANO Megumi 中野 めぐみ

Research Projects

Research Products

Co-Researchers

Analysis of mechanism involved in the assembly balance between centromere chromatin and/or heterochromatin and in higher cellular regulation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene functional analysis system using human artificial chromosome in mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The construction of multi-chromatin inducible human artificial chromosome (HAC)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of chromatin network involving centromere functional components

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The analysis of basic chromosomal functions using human artificial chromosomes (HACs) and the development of novel HACs.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 染色体分配装置セントロメアの形成メカニズム、蛋白質核酸酵素(54 査読無し)2009

Author(s)

Data Source

[Journal Article] Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Breaking the HAC Barrier : Histone H3K9 acetyl/methyl balance regulates CENP-A assembly2012

Author(s)

Journal Title

Data Source

[Journal Article] Organization of Synthetic Alphoid DNA Array in Human Artifcial Chromosome (HAC) with a Conditional Centromere2012

Author(s)

Journal Title

Data Source

[Journal Article] Epigenetic Engineering : Histone H3K9 acetylation is compatible with kinetochore structure and function2012

Author(s)

Journal Title

Data Source

[Journal Article] Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere2012

Author(s)

Journal Title

Data Source

[Journal Article] Human Artificial Chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells2011

Author(s)

Journal Title

Data Source

[Journal Article] Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier.2009

Author(s)

Journal Title

Data Source

[Journal Article] 染色体分配装置セントロメアの形成メカニズム2009

Author(s)

Journal Title

Data Source

[Journal Article] 染色体分配装置セントロメアの形成メカニズム2009

Author(s)

Journal Title

Data Source

[Journal Article] Inactivation of a human kinetochore by specific targeting of chromatin modifiers.2008

Author(s)

Journal Title

Data Source

[Journal Article] Inactivation of a human kinetochore by specific targeting of chromatin modifiers2008

Author(s)

NAKANO Megumi 中野めぐみ