MURATA ASAKO 村田亜沙子

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MURATA Asako 村田亜沙子

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Researcher Number	50557121
Other IDs	https://orcid.org/0000-0003-2073-7272
Affiliation (Current)	2025: 九州大学, 総合理工学研究院, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 九州大学, 総合理工学研究院, 准教授 2019 – 2021: 大阪大学, 産業科学研究所, 准教授 2012 – 2018: 大阪大学, 産業科学研究所, 助教 2016: 大坂大学, 産業科学研究所, 助教 2011: 大阪大学, 産業科学研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Chemical biology / Medium-sized Section 37:Biomolecular chemistry and related fields / Chemical biology Except Principal Investigator Chemistry / Science and Engineering / Chemical biology
Keywords	Principal Investigator 低分子化合物 / RNA / 翻訳制御 / 合成小分子 / バイオテクノロジー / 小分子化合物 / マイクロRNA / 創薬 / Dicer / 低分子 … More / 機械学習 / 分子設計 / 探索 / データ・情報解析 / ビッグデータ / 相互作用 / 立体構造解析 / タンパク質輸送・局在 / －１リボソームフレームシフト / RNA２次構造 / 小分子 / RNA二次構造 / リボソーマルフレームシフト / 翻訳–1フレームシフト / 翻訳－1フレームシフト / 翻訳－１フレームシフト / －1リボソーマルフレームシフト / RNA高次構造 / バイオテクロノジー / 発現制御 / 核酸 / cell-based セレクション / cell-basedセレクション … More Except Principal Investigator プロープ / RNA機能調節 / 伸長抑制 / プローブ / 小分子 / 分子合成 / スクリーニング / 分子設計 / 遺伝子疾患 / 低分子 / 毒性RNA / 神経変性疾患 / 核酸結合低分子 / トリヌクレオチドリピート / インビトロセレクション / 8位置換プリン / ライブラリー / ８位置換プリン化合物 / doped library / リボスイッチ / in vivo セレクション / ８位置換プリン誘導体 / reengineering / riboswitch / chemical library / 8-substituted purine / synthesis Less

Elucidation of the novel RNA secondary structure induced by a small moleculePrincipal Investigator
- Principal Investigator
  
  村田亜沙子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyushu University
  Osaka University
Development of a method for comprehensively analyzing the interaction between RNA and small molecule and analysis on big data of the RNA-small molecule binding pairsPrincipal Investigator
- Principal Investigator
  
  村田亜沙子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyushu University
Small-molecule induced –1 ribosomal frameshifting and its application to the control of protein transport and localizationPrincipal Investigator
- Principal Investigator
  
  Murata Asako
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Osaka University
Induction of -1 ribosomal frameshifting by a small molecule and its application to protein transport and localizationPrincipal Investigator
- Principal Investigator
  
  Murata Asako
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding Molecules
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Osaka University
Modulation of pre-miRNA processing by a small-moleculePrincipal Investigator
- Principal Investigator
  
  Murata Asako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Synthesis of 8-substituted purine chemical library and riboswitch-reengineering
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Gene regulation by using an ligand-responsive miRNA pathwayPrincipal Investigator
- Principal Investigator
  
  MURATA Asako
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit2022
- Author(s)
  Hsu Hsiu-Ting、Murata Asako、Dohno Chikara; Nakatan Kazuhiko、Chang Kung Yao
- Journal Title
  
  Nucleic Acids Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355
[Journal Article] HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules2022
- Author(s)
  Mukherjee Sanjukta、Murata Asako、Ishida Ryoga、Sugai Ayako、Dohno Chikara、Hamada Michiaki、Krishna Sudhir、Nakatani Kazuhiko
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 27 Pages: 165-174
- DOI
  10.1016/j.omtn.2021.11.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05879, KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22254, KAKENHI-PROJECT-17K20032, KAKENHI-PROJECT-19H00924
[Journal Article] Inhibitory Effects of Mismatch Binding Molecules on the Repair Reaction of Uracil-Containing DNA2022
- Author(s)
  Ulhusna Anisa、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Biochemistry
  
  Volume: 61 Issue: 22 Pages: 2522-2530
- DOI
  10.1021/acs.biochem.2c00344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-22H00351, KAKENHI-PROJECT-23K21158
[Journal Article] Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding2022
- Author(s)
  Takashima Yusuke、Murata Asako、Iida Kei、Sugai Ayako、Hagiwara Masatoshi、Nakatani Kazuhiko
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 17 Issue: 10 Pages: 2817-2827
- DOI
  10.1021/acschembio.2c00452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-23K21158
[Journal Article] 2-Amino-1,8-naphthyridine Dimer (ANP77), a High-Affinity Binder to the Internal Loops of C/CC and T/CC Sites in Double-Stranded DNA2021
- Author(s)
  Das Bimolendu、Nagano Konami、Kawai Gota、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 87 Issue: 1 Pages: 340-350
- DOI
  10.1021/acs.joc.1c02383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] Speeding drug discovery targeting RNAs: An iterative “RNA selection-compounds screening cycle“ for exploring RNA-small molecule pairs2021
- Author(s)
  Furuzono Tomoko、Murata Asako、Okuda Satoshi、Mizutani Kenji、Adachi Tsuyoshi、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 36 Pages: 116070-116070
- DOI
  10.1016/j.bmc.2021.116070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] Small Molecule-Induced Dimerization of Hairpin RNA Interfered with the Dicer Cleavage Reaction2021
- Author(s)
  Murata Asako、Mori Yuki、Di Yue、Sugai Ayako、Das Bimolendu、Takashima Yusuke、Nakatani Kazuhiko
- Journal Title
  
  Biochemistry
  
  Volume: 60 Issue: 4 Pages: 245-249
- DOI
  10.1021/acs.biochem.0c00920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] A small-molecule fluorescence probe ANP77 for sensing RNA internal loop of C, U and A/CC motifs and their binding molecules2021
- Author(s)
  Das Bimolendu、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 15 Pages: 8462-8470
- DOI
  10.1093/nar/gkab650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19H00924
[Journal Article] The dimeric form of 1, 3 - diaminoisoquinoline derivative rescued the mis - splicing of Atp2a1 and Clcn1 genes in myotonic dystrophy type 1 mouse model2020
- Author(s)
  Matsumoto, J. ; Nakamori, M. ; Okamoto, T. ; Murata, A. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 26 Issue: 63 Pages: 14305-14309
- DOI
  10.1002/chem.202001572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-16H05321
[Journal Article] A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo2020
- Author(s)
  Nakamori Masayuki, Panigrahi Gagan B., Lanni Stella, et. al.
- Journal Title
  
  Nature Genetics
  
  Volume: 52 Issue: 2 Pages: 146-159
- DOI
  10.1038/s41588-019-0575-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K07992, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-16H05321
[Journal Article] RT‐Hpro‐PCR: A MicroRNA Detection System Using a Primer with a DNA Tag2019
- Author(s)
  Takei Fumie、Akiyama Misaki、Murata Asako、Sugai Ayako、Nakatani Kazuhiko、Yamashita Ichiro
- Journal Title
  
  ChemBioChem
  
  Volume: 21 Issue: 4 Pages: 477-480
- DOI
  10.1002/cbic.201900382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K05534, KAKENHI-PROJECT-26000007
[Journal Article] Modulating RNA secondary and tertiary structures by mismatch binding ligands2019
- Author(s)
  Murata Asako、Nakamori Masayuki、Nakatani Kazuhiko
- Journal Title
  
  Methods
  
  Volume: 167 Pages: 78-91
- DOI
  10.1016/j.ymeth.2019.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-16H05321
[Journal Article] Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136?BzDANP?Dicer2019
- Author(s)
  Otabe Takahiro、Nagano Konami、Kawai Gota、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 10 Pages: 2140-2148
- DOI
  10.1016/j.bmc.2019.03.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-26000007
[Journal Article] Structural insights into synthetic ligands targeting A?A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Mukherjee Sanjukta、Blaszczyk Leszek、Rypniewski Wojciech、Falschlunger Christoph、Micura Ronald、Murata Asako、Dohno Chikara、Nakatani Kazuhiko、Kiliszek Agnieszka
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 20 Pages: 10906-10913
- DOI
  10.1093/nar/gkz832
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-26000007
[Journal Article] A Dimeric 2,9‐Diamino‐1,10‐phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models2018
- Author(s)
  Li Jinxing、Nakamori Masayuki、Matsumoto Jun、Murata Asako、Dohno Chikara、Kiliszek Agnieszka、Taylor Katarzyna、Sobczak Krzysztof、Nakatani Kazuhiko
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 24 Issue: 68 Pages: 18115-18122
- DOI
  10.1002/chem.201804368
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-15K15339, KAKENHI-PROJECT-16H05321, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-17J02038, KAKENHI-PROJECT-26000007
[Journal Article] Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting2018
- Author(s)
  Matsumoto Saki、Caliskan Neva、Rodnina Marina V、Murata Asako、Nakatani Kazuhiko
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 46 Issue: 16 Pages: 8079-8089
- DOI
  10.1093/nar/gky689
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] Synthetic ligand promotes gene expression by affecting GC sequence in promoter2017
- Author(s)
  Matsumoto Saki、Iida Kei、Murata Asako、Denawa Masatsugu、Hagiwara Masatoshi、Nakatani Kazuhiko
- Journal Title
  
  Bioorganic & medicinal chemistry letters
  
  Volume: 27 Issue: 15 Pages: 3391-3394
- DOI
  10.1016/j.bmcl.2017.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] Synthesis of naphthyridine dimers with conformational restriction and the binding to DNA and RNA2017
- Author(s)
  Nakatani, K. ; Natsuhara, N. ; Mori, Y. ; Mukherjee, S. ; Das, B. ; and Murata, A.
- Journal Title
  
  Chem. Asian J.
  
  Volume: 12 Issue: 23 Pages: 3077-3087
- DOI
  10.1002/asia.201701293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] BzDANP, a small-molecule modulator of pre-miR-29a maturation by Dicer2016
- Author(s)
  Murata, A. ; Otabe, T. ; Zhang, J. ; Nakatani, K
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 11 Issue: 10 Pages: 2790-2796
- DOI
  10.1021/acschembio.6b00214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] A Ligand that Targets CUG Trinucleotide Repeats2016
- Author(s)
  Li. J.; Matsumoto, J.; Bai, L.-P.; Murata, A.; Dohno, A.; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 22 Issue: 42 Pages: 14881-14889
- DOI
  10.1002/chem.201602741
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] Naphthyridine-Benzoazaquinolone : Evaluation of tricyclic system for the binding to (CAG)n Repeat DNA and RNA2016
- Author(s)
  Fukuzumi, T. ; Murata, A. ; Aikawa, H. ; Harada, Y. ; Nakatani, K.
- Journal Title
  
  Chem. Asian. J.
  
  Volume: 21 Issue: 13 Pages: 1971-1981
- DOI
  10.1002/asia.201600527
- Description
  in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-15K01820
[Journal Article] Exploratory Study on the RNA-Binding Structural Motifs by Library Screening Targeting pre-miRNA-29a.2015
- Author(s)
  Fukuzumi, T.; Murata, A.; Aikawa, H.; Harada, Y.: Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 47 Pages: 16859-16867
- DOI
  10.1002/chem.201502913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-25750393, KAKENHI-PROJECT-26000007
[Journal Article] Synthesis of 8-substituted adenine and adenosine libraries and the binding to pre-miR-29a2014
- Author(s)
  Fukuzumi, T.; Aikawa, H.; Harada, Y.; Sugai, A.; Murata, A.; Nakatani, K.
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 87 Issue: 9 Pages: 1013-1015
- DOI
  10.1246/bcsj.20140137
- NAID
  130004687252
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25750393, KAKENHI-PROJECT-26000007
[Journal Article] Formation of Ligand-Assisted Complex of Two RNA Hairpin Loops2014
- Author(s)
  Changfeng Hong, Takahiro Otabe, Saki Matsumoto, Chikara Dohno, Asako Murata, Masaki Hagihara, Kazuhiko Nakatani
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 20 Issue: 18 Pages: 5244-5252
- DOI
  10.1002/chem.201304683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J05460, KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25350958, KAKENHI-PROJECT-26000007
[Journal Article] Fluorescent indicator displacement assay of ligands targeting 10 microRNA precursors2013
- Author(s)
  Murata, A.; Harada, Y.; Fukuzumi, T.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 22 Pages: 7101-7106
- DOI
  10.1016/j.bmc.2013.09.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-25750393
[Journal Article] Ligand-inducible formation of RNA pseudoknot2013
- Author(s)
  Matsumoto, S., Hong, C; Otabe, T.; Murata, A.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Issue: 12 Pages: 3539-3541
- DOI
  10.1016/j.bmcl.2013.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-25750393
[Journal Article] Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules.2013
- Author(s)
  Asako Murata, Takeo Fukuzumi, Shiori Umemoto, Kazuhiko Nakatani
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23 Issue: 1 Pages: 252-255
- DOI
  10.1016/j.bmcl.2012.10.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-24710262
[Journal Article] Structure-activity studies on the fluorescent indicator in the displacement assay for the screening of small molecules binding to RNA2012
- Author(s)
  Umemoto, S.; Im, S.; Zhang, J.; Hagihara, M.; Murata, A.; Harada, Y.; Fukuzumi, T.; Wazaki, T.; Sasaoka, S.; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 18 Pages: 9999-10008
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Structure-activity studies on the fluorescent indicator in the displacement assay for the screening of small molecules binding to RNA2012
- Author(s)
  Shiori Umemoto, Seongwang Im, Jinhua Zhang, Masaki Hagihara, Asako Murata, Yasue Harada, Takeo Fukuzumi, Takahiro Wazaki, Shin-ichi Sasaoka, and Kazuhiko Nakatani
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710270
[Journal Article] Structure-activity studies on the fluorescent indicator in the displacement assay for the screening of small molecules binding to RNA.2012
- Author(s)
  Shiori Umemoto, Seongwang Im, Jinhua Zhang, Masaki Hagihara, Asako Murata, Yasue Harada, Takeo Fukuzumi, Takahiro Wazaki, Shin-ichi Sasaoka, and Kazuhiko Nakatani
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 18 Issue: 32 Pages: 9999-10008
- DOI
  10.1002/chem.201103932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710270, KAKENHI-PROJECT-24710262
[Presentation] Interaction between a small molecule, NA, and an RNA with the ACG/AUA internal loop2023
- Author(s)
  Aina Fujiwara, Qingwen Chen, Asako Murata, Kazuhiko Nakatani, Gota Kawai
- Organizer
  The 50th International Symposium on Nucleic Acids Chemistry (ISNAC2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Evaluation of APOBEC-catalyzed cytosine deamination for the repeat DNAs with binding small molecules binding2023
- Author(s)
  Luyan Zhang, Tomonori Shibata, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 50th International Symposium on Nucleic Acids Chemistry (ISNAC2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Evaluation of the effect of small-molecule binding to mRNA on ribosomal frameshifting in SARS-CoV-22022
- Author(s)
  Asako Murata, Hiyori Fujii, Risa Anami, Ayako Sugai,, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] A Fluorescence Probe ANP77 for Sensing RNA Internal Loops and Their Binding Molecules2022
- Author(s)
  Bimolendu Das, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Machine learning assisted classification of small molecules targeting CAG repeat DNA2022
- Author(s)
  Qingwen Chen, Takeshi Yamada, Asako Murata, Yasuyuki Matsushita, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2025)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] Evaluation of APOBEC-catalyzed cytosine deamination for the repeat DNAs2022
- Author(s)
  Luyan Zhang, Tomonori Shibata, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] A rapid method for obtaining the interacting pairs of RNA-small molecule and its statistical analysis2022
- Author(s)
  Yusuke Takashima, Asako Murata, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] Inhibition of the Activity of Base Excision Repair Enzymes by Mismatch Binding Ligand Binding to Uracil-containing DNA2022
- Author(s)
  Anisa Ulhusna, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] An RNA internal loop of C, U and A/CC motifs specific fluorescence probe ANP772022
- Author(s)
  Anisa Ulhusna, Asako Murata, Kazuhiko Nakatani
- Organizer
  XXIV International Round Table (IRT2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Inhibition of the Activity of Base Excision Repair Enzymes by Mismatch Binding Ligand Binding to Uracil-containing DNA2022
- Author(s)
  Anisa Ulhusna, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Computer-aided classification of small molecules targeting CAG-repeat DNA2022
- Author(s)
  Lu Ni, Takeshi Yamada, Asako Murata, Kazuhiko Nakatani
- Organizer
  XXIV International Round Table (IRT2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Machine learning assisted classification of small molecules targeting CAG repeat DNA2022
- Author(s)
  Qingwen Chen, Takeshi Yamada, Asako Murata, Yasuyuki Matsushita, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] A Fluorescence Probe ANP77 for Sensing RNA Internal Loops and Their Binding Molecules2022
- Author(s)
  Bimolendu Das, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] A rapid method for obtaining the interacting pairs of RNA-small molecule and its statistical analysis2022
- Author(s)
  Yusuke Takashima, Asako Murata, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] Dicer酵素切断を活用したRNA標的低分子の機能性スクリーニング2022
- Author(s)
  髙島裕介、村田亜沙子、中谷和彦
- Organizer
  RNAフロンティアミーティング
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] Guanine-guanine Mismatch Binding Ligand Inhibition to Base Excision Repair Enzymes窶? Reactions In Vitro2022
- Author(s)
  Anisa Ulhusna , Asako Murata, Kazuhiko Nakatani
- Organizer
  XXIV International Round Table (IRT2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21158
[Presentation] Synthesis and the properties of naphthyridine-azaquinolone dimer (NAD) tatgeting CAG-repeat RNA2021
- Author(s)
  Qingwen Chen, Takeshi Yamada, Asako Murata, Kazuhiko Nakatani
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] An RNA internal loop of C, U and A/CC motifs specific fluorescence probe ANP772021
- Author(s)
  Bimolendu Das, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry (ISNAC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] SARS-CoV-2フレームシフトシグナルを標的とする低分子化合物の表面プラズモン共鳴(SPR)アッセイによるスクリーニング2021
- Author(s)
  藤井　陽和、村田亜沙子、中谷和彦
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Regulation of circular RNA biogenesis using nucleic acid binding small molecule in cellular environment2021
- Author(s)
  Lu Ni, Takeshi Yamada, Asako Murata, Kazuhiko Nakatani
- Organizer
  The International Chemical Congress of Pcific Basin Societies 2021 (Pacifichem 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Using machine learning to classify and extract features of small-molecule libraries targeting DNA and RNA2021
- Author(s)
  Qingwen Chen, Yasuyuki Matsushita, Asako Murata, Takeshi Yamada, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  The International Chemical Congress of Pcific Basin Societies 2021 (Pacifichem 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Regulation of circular RNA biogenesis via nucleic acid binding small molecule in cells2021
- Author(s)
  Lu Ni, Takeshi Yamada, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry (ISNAC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Effect of Guanine-guanine Mismatch Binding Ligand on Repair Enzymes' reactions in vitro2021
- Author(s)
  Anisa Ul'Husna, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry (ISNAC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Identification of small molecules that can bind to the SARS-CoV-2 frameshifting signal by SPR-based screening of chemical libraries2021
- Author(s)
  Hiyori Fujii, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry (ISNAC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Cell-based screening of chemical libraries for small molecules that target SARS-CoV-2 frameshifting signal2021
- Author(s)
  Risa Anami, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry (ISNAC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Dicer切断産物のハイスループットシーケンシングによる RNA-小分子結合モチーフの同定2021
- Author(s)
  高島　裕介、村田亜沙子、中谷和彦
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Regulation of circular RNA biogenesis via RNA binding small molecule2021
- Author(s)
  Lu Ni, Takeshi Yamada, Asako Murata, Kazuhiko Nakatani
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Computer-aided classification of small molecules targeting CAG-repeat DNA2021
- Author(s)
  Qingwen Chen, Asako Murata, Takeshi Yamada, Ayako Sugai, Yasuyuki Matsushita, Kazuhiko Nakatani
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry (ISNAC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19050
[Presentation] Controlling -1 ribosomal frameshifting by small molecules in cells2020
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  The 23rd SANKEN INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and the properties of NA Dimer2020
- Author(s)
  Chen Qingwen, Yamada Takeshi, Murata Asako, Nakatani Kazuhiko
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Comprehensive Analysis of Dicer Substrates by High-Throughput Sequencing Identified New Target RNA Motifs for Small Molecules2020
- Author(s)
  Asako Murata, Yusuke Takashima, Kei Iida, Ayako Sugai, Masatoshi Hagiwara, Kazuhiko Nakatani
- Organizer
  The 43rd Annual Meeting of the Molecular Biology Society of Japan (MBSJ2020)
- Invited
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Controlling -1 ribosomal frameshifting by small molecules in cells2020
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  The 23rd SANKEN INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Dicer切断反応を指標としたRNA結合分子標的配列の網羅的解析2020
- Author(s)
  高島裕介、村田亜沙子、中谷和彦
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Kinetic analysis of the inhibitory effect of BzDANP on Dicer cleavage of pre-miR-1362019
- Author(s)
  Asako Murata, Takahiro Otabe, Konami Nagano, Gota Kawai, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Exploration of RNA sequences in pre-miRNA affecting the efficiency of Dicer cleavage reactions by the small molecules binding2019
- Author(s)
  Yusuke Takashima, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Sanjukta Mukherjee, Leszek Blaszczyk, Wojciech Rypniewski, Christoph Falschlunger, Ronald Micura, Asako Murata, Chikara Dohno, Kazuhiko Nakatani, Agnieszka Kiliszek
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Kinetic analysis of the inhibitory effect of BzDANP on Dicer cleavage of pre-miR-1362019
- Author(s)
  Asako Murata, Takahiro Otabe, Konami Nagano, Gota Kawai, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Sanjukta Mukherjee, Leszek Blaszczyk, Wojciech Rypniewski, Christoph Falschlunger, Ronald Micura, Asako Murata, Chikara Dohno, Kazuhiko Nakatani, Agnieszka Kiliszek
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Exploration of RNA sequences in pre-miRNA affecting the efficiency of Dicer cleavage reactions by the small molecules binding2019
- Author(s)
  Yusuke Takashima, Asako Murata, Kazuhiko Nakatani
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Dicer切断を阻害するRNA結合分子標的配列の網羅的解析2019
- Author(s)
  高島祐介、村田亜沙子、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Rational design of CUG repeat binging molecule targeting Myotonic Dystrophy type 12018
- Author(s)
  Jun Matsumoto, Jinxing Li, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Roundtable of Nucleosides, Nucleotides, and Nucleic Acids (IRT)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Masayuki Nakamori, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthetic small molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting2018
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01820
[Presentation] Synthetic small molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting2018
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355
[Presentation] Synthetic small molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting2018
- Author(s)
  Asako Murata, Saki Matsumoto, Neva Caliskan, Marina V. Rodnina, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] A Novel Riboswitch Strategy by Utilize Mismatch Binding Ligand (MBL)2017
- Author(s)
  A. U1' Husna, S. Matsumoto, A. Murata, K. Nakatani
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Novel isoquinoline derivatives that inhibit MBNL1-CUG repeat interaction in Myotonic Dystrophy typel2017
- Author(s)
  J. Matsumoto, J. Li, A. Murata, C. Dohno, K. Nakatani
- Organizer
  ISNAC 2017 (The 44th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Designing small molecules targeting CUG repeats causing Myotonic Dystrophy type 12017
- Author(s)
  J. Li, J. Matsumoto, B. Li-Ping, A. Murata, C. Cohno, K. Nakatani
- Organizer
  RNA 2017 (The 22nd Annual Meeting of the RNA Society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] In vitro selection of pre-miR-29a loop mutant against the cyclic mismatch binding ligand (CMBL)2016
- Author(s)
  Sanjukta Mukherjee, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2016
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートDNAおよびRNAを標的としたナフチリジンーアザキノロン誘導体の開発と転写および翻訳への阻害効果2016
- Author(s)
  阪田彬裕, 村田亜沙子, 李金星, 松本咲, Li-ping BAI, 堂野主税, 小比賀聡, 中谷和彦
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 小分子化合物によるマイクロRNA生成阻害の速度論的解析2016
- Author(s)
  小田部尭広、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of Gene Expression by Ligand-Inducible -1 Ribosomal Frameshifting2016
- Author(s)
  Saki Matsumoto、Asako Murata、Kazuhiko Nakatani
- Organizer
  Aptamers in Bordeaux
- Place of Presentation
  University of Bordeaux France
- Year and Date
  2016-06-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Ligand-inducible –1 ribosomal frameshifting in the cells2016
- Author(s)
  松本　咲・村田　亜沙子・中谷　和彦
- Organizer
  日本化学会第９６春季年会
- Place of Presentation
  京都
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K01820
[Presentation] A small-molecule inhibitor of pre-miR-29 maturation2015
- Author(s)
  Asako Murata, Takahiro Otabe, Jinhua Zhang, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Analysis of binding of naphthyridine-azaquinolone derivatives to CAG repeats RNA2015
- Author(s)
  Akihiro Sakata, Jinxing Li, Hanping He, Asako Murata, Chikara Dohno, Satoshi Obika, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii(USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートDNAおよびRNAとナフチリジンーアザキノロン誘導体とのSPRによる結合評価2015
- Author(s)
  阪田彬裕、李金星、Hanping He、Li-ping Bai、村田亜沙子、堂野主税、小比賀聡、中谷和彦
- Organizer
  GE Life Sciences Day 2015
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Small molecule-Loop Interaction that interferes the maturation on process of pre-miRNA by Dicer2015
- Author(s)
  Yuki Mori, Yue Di, Ayako Sugai, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  姫路
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Regulation of gene expression by ligand-inducible -1 ribosomal frameshifting2015
- Author(s)
  Saki Matsumoto, Asako Murata, Changfeng Hong, Kazuhiko Nakatani
- Organizer
  ECBS & ICBS joint meeting 2015
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01820
[Presentation] マイクロRNA前駆体結合分子の探索2015
- Author(s)
  相川春夫、福澄岳雄、原田恭枝、須貝亜矢子、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  東北大学川内キャンバス(宮城県・仙台市)
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Regulation of gene expression by ligand-inducible -1 ribosomal frameshifting2015
- Author(s)
  Saki Matsumoto, Asako Murata, Changfeng Hong, Kazuhiko Nakatani
- Organizer
  RNA2015, The 20th Annual Meeting of the RNA Society
- Place of Presentation
  Wisconsin, USA
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01820
[Presentation] 小分子誘起型-1リボソームフレームシフトによる遺伝子発現制御システムの開発2015
- Author(s)
  松本咲・村田亜沙子・中谷和彦
- Organizer
  細胞をつくる会
- Place of Presentation
  大阪
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K01820
[Presentation] 小分子による-1リボソーマルフレームシフト誘起とタンパク質の輸送・局在制御への応用2015
- Author(s)
  村田亜沙子・松本咲・洪昌峰・中谷和彦
- Organizer
  第38回分子生物学会年会　第88回日本生化学会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K01820
[Presentation] SPR-based in vitro selection of pre-miRNA loop mutant molecules that bind to the restrained naphthyridine dimer2015
- Author(s)
  Yuki Mori, Yue Di, Ayako Sugai, Asako Murata, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Synthesis and Binding Property of Naphthyridine-Azaquinolone Derivatives Targeting (CAG)n Repeat RNA2015
- Author(s)
  Akihiro Sakata, Jinxing Li, Hanping He, Li-ping Bai, Asako Murata, Chikara Dohno, Satoshi Obika, and Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートRNAを標的としたナフチリジン-アザキノロン誘導体の機能評価2015
- Author(s)
  阪田彬裕, 村田亜沙子, 李金星, 松本咲, Li-ping BAI, 堂野主税, 小比賀聡, 中谷和彦
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ(京都府・京都市)
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] In vitro selection of pre-miRNA loop mutant molecules that bind to the restrained naphthyridine dimer2015
- Author(s)
  Asako Murata, Yuki Mori, Yue Di, Ayako Sugai, Kazuhiko Nakatani
- Organizer
  RNA2015, The 20th Annual Meeting of the RNA Society
- Place of Presentation
  Wisconsin, USA
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] RNAの構造・機能を制御する小分子化合物の開発2014
- Author(s)
  村田亜沙子
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] RNAの構造・機能を制御する小分子化合物の開発2014
- Author(s)
  村田亜沙子
- Organizer
  日本化学会第９４春季年会
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] RNAの構造・機能を制御する小分子化合物の開発2014
- Author(s)
  村田亜沙子
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] RNA結合性化合物を用いたマイクロRNA前駆体プロセシングの調節2013
- Author(s)
  村田亜沙子・福澄岳雄・梅本詩織・神山いづみ・堂野主税・中谷和彦
- Organizer
  日本化学会第９３春季年会
- Place of Presentation
  立命館大学（滋賀県）
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Translational regulation by ligand-inducible formation of RNA pseudoknot2013
- Author(s)
  Saki Matsumoto, Changfeng Hong, Asako Murata, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Davos, Switzerland)
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Suppression of miR-29a maturation by ligand binding2013
- Author(s)
  Takahiro Otabe, Asako Murata, Fumie Takei, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Davos, Switzerland)
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing2013
- Author(s)
  Murata , A.; Sugai, A.; Fukuzumi, T.; Umemoto, S.; Dohno, C.; Nakatani, K.
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Switzerland)
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing2013
- Author(s)
  Asako Murata, Ayako Sugai, Takeo Fukuzumi, Shiori Umemoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Davos, Switzerland)
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] RNA結合性化合物を用いたマイクロRNA 前駆体プロセシングの調節2013
- Author(s)
  村田亜沙子・福澄岳雄・梅本詩織・神山いづみ・堂野主税・中谷和彦
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学(滋賀県)
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Synthesis of the restrained naphthyridine dimer and the exploration for binding RNA by in vitro selection2013
- Author(s)
  Yue Di, Takahiro Otabe, Jinxing Li, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2013
- Place of Presentation
  神奈川大学（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Synthesis of the restrained naphthyridine dimer and the exploration for binding RNA by in vitro selection2013
- Author(s)
  Yue Di, Takahiro Otabe, Jinxing Li, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2013
- Place of Presentation
  神奈川大学（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing2013
- Author(s)
  Asako Murata, Ayako Sugai, Takeo Fukuzumi, Shiori Umemoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Davos, Switzerland)
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Suppression of miR-29a maturation by ligand binding2013
- Author(s)
  Takahiro Otabe, Asako Murata, Fumie Takei, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Davos, Switzerland)
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Translational regulation by ligand-inducible formation of RNA pseudoknot2013
- Author(s)
  Saki Matsumoto, Changfeng Hong, Asako Murata, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos (Davos, Switzerland)
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Translation regulation of gene expression by small molecule-induced pseudoknot formation2012
- Author(s)
  S. Matsumoto, C. Hong, A. Murata, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012
- Author(s)
  T. Fukuzumi, A. Murata, Y. Harada, K. Nakatani
- Organizer
  RNA 2012, the 17th Annual Meeting of the RNA Society
- Place of Presentation
  ミシガン大学 USA
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] High-throughput Screening of Chemical Libraries for the Discovery of RNA-binding Compounds2012
- Author(s)
  Asako Murata, Yasue Harada, Takeo Fukuzumi, Shiori Umemoto, Seongwang Im, Masaki Hagihara, Kazuhiko Nakatani
- Organizer
  RNA 2012, the 17th Annual Meeting of the RNA Society
- Place of Presentation
  University of Michigan (Ann Arbor, Michigan, USA)
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] 大規模化合物ライブラリーのスクリーニングによる，RNA結合性化合物の探索2012
- Author(s)
  村田亜沙子, 原田恭枝, 福澄岳雄, 梅本詩織, 任仙光, 萩原正規, 中谷和彦
- Organizer
  日本化学会第92回春季年会
- Place of Presentation
  慶応義塾大学（神奈川県）
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Synthesis of Small Molecule Library for pre-miRNA Secondary Structures2012
- Author(s)
  T. Fukuzumi, A. Murata, Y. Harada, K. Nakatani
- Organizer
  IKCOC-12
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] High-throughput Screening of Chemical Libraries for the Discovery of RNA-binding Compounds2011
- Author(s)
  Asako Murata, Yasue Harada, Takeo Fukuzumi, Shiori Umemoto, Seongwang Im, Masaki Hagihara and Kazuhiko Nakatani
- Organizer
  RNA 2011
- Place of Presentation
  国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] Fluorescent indicator displacement assay for the discovery of RNA-binding ligands2011
- Author(s)
  Asako Murata, Yasue Harada, Takeo Fukuzumi, Shiori Umemoto, Seongwang Im, Masaki Hagihara and Kazuhiko Nakatani
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23710270
[Presentation] In vitro selection of pre-miR-29a loop mutant library against the restrained naphthyridine dimer
- Author(s)
  Yuki Mori, Yue Di, Ayako Sugai, Takahiro Otabe, Jinxin Li, Haruo Aikawa, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2014
- Place of Presentation
  北九州国際会議場（福岡県、小倉
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] Translational regulation by ligand-inducible formation of RNA pseudoknot
- Author(s)
  Saki Matsumoto, Changfeng Hong, Asako Murata, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] SPRを用いたin vitro selectionによるRND(the restrained naphthyridine dimer)結合性RNAアプタマーの探索
- Author(s)
  森友紀、邸つき、須貝亜矢子、李金星、小田部尭広、相川春夫、村田亜沙子、中谷和彦
- Organizer
  日本化学会第９５春季年会
- Place of Presentation
  日本大学（千葉県、船橋）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] BzDANPによるRNAプロセシング阻害の速度論的解析
- Author(s)
  小田部尭広、村田亜沙子、中谷和彦
- Organizer
  日本化学会第９５春季年会
- Place of Presentation
  日本大学（千葉県、船橋）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] 小分子によるリボソームフレームシフトの制御
- Author(s)
  松本咲、村田亜沙子、洪昌峰、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学会館
- Year and Date
  2014-06-11 – 2014-06-13
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing
- Author(s)
  Asako Murata, Ayako Sugai, Takeo Fukuzumi, Shiori Umemoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] RNA結合性小分子の創成を指向したエンタルピー駆動型分子の設計と合成
- Author(s)
  夏原望、邸つき、Mukherjee　Sanjukta、村田亜沙子、中谷和彦
- Organizer
  日本化学会第９５春季年会
- Place of Presentation
  日本大学（千葉県、船橋）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] 小分子によるmiR-29a成熟過程の阻害
- Author(s)
  小田部尭広、村田亜沙子、武井史恵、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第９回年会
- Place of Presentation
  大阪大学（大阪府，豊中）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25750393
[Presentation] 8位アリール置換型アデニン誘導体の合成とpre-miR-29aに対する結合評価
- Author(s)
  相川春夫、福澄岳雄、原田恭枝、須貝亜矢子、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学会館
- Year and Date
  2014-06-11 – 2014-06-13
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Suppression of miR-29a maturation by ligand binding
- Author(s)
  OTABE, Takahiro; MURATA, Asako; TAKEI, Fumie; NAKATANI, Kazuhiko
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] 小分子で誘起されたRNAシュードノット構造によるフレームシフト機構の制御
- Author(s)
  松本咲、洪昌峰、村田亜沙子、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会　第８回年会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2013-06-19 – 2013-06-21
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] 小分子とトリヌクレオチドリピートDNAおよびRNAとのSPRによる結合評価
- Author(s)
  阪田彬裕, 李金星, 何漢平, 小比賀聡, 村田亜沙子, 中谷和彦
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-25 – 2015-03-28
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Suppression of miR-29a maturation by synthetic ligand
- Author(s)
  Takahiro Otabe, Jinxin Li, Asako Murata, Kazuhiko Nakatani
- Organizer
  ISNAC2014
- Place of Presentation
  北九州国際会議場（福岡県、小倉）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25750393

1. NAKATANI Kazuhiko (70237303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 73 results
2. TAKEI Fumie (30252711)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. DOHNO Chikara (60420395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. AIKAWA Haruo (70547322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. Nakamori Masayuki (60630233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. HAGIHARA Masaki (40403000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. FUKUZUMI Takeo (00592768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 浅井歩 (40783262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMADA Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SHIBATA Tomonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI Masanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAGAI Takeharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 浜田道昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MURATA ASAKO 村田 亜沙子

MURATA Asako 村田 亜沙子

Research Projects

Research Products

Co-Researchers

Elucidation of the novel RNA secondary structure induced by a small moleculePrincipal Investigator

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Development of a method for comprehensively analyzing the interaction between RNA and small molecule and analysis on big data of the RNA-small molecule binding pairsPrincipal Investigator

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Small-molecule induced &#8211;1 ribosomal frameshifting and its application to the control of protein transport and localizationPrincipal Investigator

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Induction of -1 ribosomal frameshifting by a small molecule and its application to protein transport and localizationPrincipal Investigator

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Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding Molecules

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Modulation of pre-miRNA processing by a small-moleculePrincipal Investigator

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Synthesis of 8-substituted purine chemical library and riboswitch-reengineering

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Gene regulation by using an ligand-responsive miRNA pathwayPrincipal Investigator

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[Journal Article] Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit2022

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[Journal Article] HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules2022

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[Journal Article] Inhibitory Effects of Mismatch Binding Molecules on the Repair Reaction of Uracil-Containing DNA2022

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[Journal Article] Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding2022

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[Journal Article] 2-Amino-1,8-naphthyridine Dimer (ANP77), a High-Affinity Binder to the Internal Loops of C/CC and T/CC Sites in Double-Stranded DNA2021

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[Journal Article] Speeding drug discovery targeting RNAs: An iterative “RNA selection-compounds screening cycle“ for exploring RNA-small molecule pairs2021

Author(s)

Journal Title

MURATA ASAKO 村田亜沙子

MURATA Asako 村田亜沙子

Small-molecule induced –1 ribosomal frameshifting and its application to the control of protein transport and localizationPrincipal Investigator