Yoshikawa Momoko 吉川桃子

… Alternative Names

YOSHIKAWA MOMOKO 吉川桃子

YOSHIKAWA Momoko 吉川桃子

吉川桃子ヨシカワモモコ

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Researcher Number	50570967
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤)
Affiliation (based on the past Project Information) *help	2021 – 2023: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2018 – 2020: 慶應義塾大学, 医学部(信濃町), 訪問研究員 2017: 慶應義塾大学, 医学部, 研究員 2017: 慶應義塾大学, 医学部, 訪問研究員 2016: 慶應義塾大学, 医学部(信濃町), 共同研究員 … More 2016: 慶應義塾大学, 医学部(信濃町), 訪問研究員 2015: 慶應義塾大学, 医学部, 共同研究員 2014 – 2015: 慶應義塾大学, 医学部, 特任助教 2012: 慶應義塾大学, 医学部, 研究員(非常勤) 2010: 慶應義塾大学, 医学部, 研究員(非常勤) Less
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Pathobiological dentistry/Dental radiology Except Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 57060:Surgical dentistry-related / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator CD44v / CD44ｖ / 口腔扁平上皮癌 / PDXモデル / セツキシマブ / 口腔癌 / PDXマウスモデル / 口腔がん / セツキシマブ耐性 / CD44 … More Except Principal Investigator … More CD44 / 口腔扁平上皮癌 / EMT / CD44v / スルファサラジン / 遺伝子変異 / 薬剤スクリーニング / TBK1 / YAP / セロトニン / 分化誘導療法 / 扁平上皮癌 / HTR7 / 遺伝子パネル検査 / 口腔 / トランスレーショナルリサーチ / 癌 / CD140a / CD326 / SpCC / グルタチオン / 腫瘍生物学 / 実験腫瘍学 Less

PDXモデルを用いた局所進行・再発転移口腔癌に対する新たな治療戦略の考案Principal Investigator
- Principal Investigator
  
  吉川桃子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Keio University
セロトニンシグナルを標的とした扁平上皮癌分化誘導療法の開発
- Principal Investigator
  
  岡崎章悟
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nihon University
Actionable遺伝子変異に基づく新たな口腔扁平上皮癌治療戦略の開発
- Principal Investigator
  
  莇生田整治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Keio University
Characterization of CD44v-positive oral cancer stem cells using PDX model and establishment of novel drug therapyPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Momoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Keio University
Identification of targetable genetic mutations and establishment of personalized therapy in standard therapy-resistant oral squamous cell carcinoma
- Principal Investigator
  
  Asoda Seiji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Keio University
Development of novel treatment targeting cancer stromal cells in standard treatment-resistant oral squamous cell carcinoma
- Principal Investigator
  
  Asoda Seiji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Keio University
Analysis of metabolic changes associated with cetuximab resistance in oral squamous cell carcinoma and designing of new treatmentPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Momoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Keio University
Development of the therapy for cetuximab-resistant oral squamous cell carcinoma cellsPrincipal Investigator
- Principal Investigator
  
  Yoshikawa Momoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Keio University
Treatment sensitivity evaluation of oral squamous cell carcinoma based on the expression of a functional cancer stem cell marker CD44v
- Principal Investigator
  
  Asoda Seiji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Keio University
New classification of oral squamous cell carcinoma based on the molecular expression profile controlling the epithelial mesenchymal transition and stem cell-like characteristics
- Principal Investigator
  
  ASODA Seiji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Keio University

All 2022 2020 2019 2018 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells2018
- Author(s)
  Ouchi T.、Morikawa S.、Shibata S.、Takahashi M.、Yoshikawa M.、Soma T.、Miyashita H.、Muraoka W.、Kameyama K.、Kawana H.、Arima Y.、Saya H.、Okano H.、Nakagawa T.、Asoda S.
- Journal Title
  
  J Dent Res
  
  Volume: ー Issue: 7 Pages: 779-786
- DOI
  10.1177/0022034518759278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K20613, KAKENHI-PROJECT-16K11521
[Journal Article] Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines2016
- Author(s)
  Ming Wang, Yutaka Miura, Kenji Tsuchihashi, Kazuki Miyano, Osamu Nagano, Momoko Yoshikawa, Ami Tanabe, Jun Makino, Yuki Mochida, Nobuhiro Nishiyama, Hideyuki Saya, Horacio Cabral, Kazunori Kataoka
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 230 Pages: 26-33
- DOI
  10.1016/j.jconrel.2016.03.038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-26861579, KAKENHI-PROJECT-16K20613
[Journal Article] The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)2016
- Author(s)
  Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H, Nagano O.
- Journal Title
  
  Cancer Research
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861579
[Journal Article] Ink4a/Arf-dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-dependent Gastric Tumorigenesis.2015
- Author(s)
  Seishima R, Wada T, Tsuchihashi K, Okazaki S, Yoshikawa M, Oshima H, Oshima M, Sato T, Hasegawa H, Kitagawa Y, Goldenring JR, Saya H, Nagano O.
- Journal Title
  
  Cancer Prevention Research
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861579
[Journal Article] xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma2013
- Author(s)
  Yoshikawa M, Tsuchihashi K, Ishimoto T, Yae T, Motohara T, Sugihara E, Onishi N, Masuko T, Yoshizawa K, Kawashiri S, Mukai M, Asoda S, Kawana H, Nakagawa T, Saya H, Nagano O
- Journal Title
  
  Cancer Res
  
  Volume: 73(6) Issue: 6 Pages: 1855-1866
- DOI
  10.1158/0008-5472.can-12-3609-t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592100, KAKENHI-PROJECT-23659941, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24592965, KAKENHI-PROJECT-24791713, KAKENHI-PROJECT-24792194, KAKENHI-PROJECT-25293344, KAKENHI-PROJECT-25870730, KAKENHI-PLANNED-22130007
[Presentation] FOXA1 suppresses oral cancer progression through inhibiting p38 activation induced by lipid-derived aldehydes2022
- Author(s)
  岡崎章悟, 吉川桃子, 相馬智也, 莇生田整治, 今井健一, 後飯塚僚, 佐谷秀行, 永野修
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K10200
[Presentation] 口腔扁平上皮癌におけるFOXA1の発現低下は腫瘍成長とxCT依存性を促進する2022
- Author(s)
  岡﨑章悟、中島由梨佳、吉川桃子、相馬智也、莇生田整治、今井健一、後飯塚僚、佐谷秀行、永野修
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K07157
[Presentation] FOXA1 suppresses oral cancer progression through inhibiting p38 activation induced by lipid-derived aldehydes2022
- Author(s)
  岡崎章悟、吉川桃子、相馬智也、莇生田整治、今井健一、後飯塚僚、佐谷秀行、永野修
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K10344
[Presentation] FOXA1 suppresses oral cancer progression through inhibiting p38 activation induced by lipid-derived aldehydes2022
- Author(s)
  岡崎章悟、吉川桃子、相馬智也、莇生田整治、今井健一、後飯塚、佐谷秀行、永野修
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07157
[Presentation] FOXA1 suppresses oral cancer progression through inhibiting p38 activation induced by lipid-derived aldehydes2022
- Author(s)
  岡崎章悟, 吉川桃子, 相馬智也, 莇生田整治, 今井健一, 後飯塚僚, 佐谷秀行, 永野修
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K10103
[Presentation] 紡錘細胞癌における間葉系幹細胞の同定とPDGFRα阻害薬を用いた細胞死の誘導2020
- Author(s)
  黄地健仁, 森川暁, 高橋萌, 吉川桃子, 相馬智也, 宮下英高, 河奈裕正, 中川種昭, 莇生田整治
- Organizer
  第74回　日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10344
[Presentation] 舌に発生した紡錘細胞癌は間葉系幹細胞の性質をもつ2019
- Author(s)
  吉川桃子、黄地健仁、森川暁、高橋萌、相馬智也、宮下英高、河奈裕正、佐谷秀行、中川種昭、莇生田整治
- Organizer
  第64回　日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10344
[Presentation] 口腔に発生した再発紡錘細胞癌における間葉系幹細胞の同定2019
- Author(s)
  吉川桃子、黄地健仁、森川暁、芝田晋介、高橋萌、相馬智也、宮下英高、村岡渡、亀山香織、河奈裕正、有馬好美、佐谷秀行、岡野栄之、中川種昭、莇生田整治
- Organizer
  第43回　日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K10344
[Presentation] セツキシマブ耐性口腔扁平上皮癌細胞に対する治療の可能性2015
- Author(s)
  吉川桃子, 莇生田整治, 森川暁, 宮下英高, 臼田慎, 河奈裕正, 中川種昭, 佐谷秀行, 永野修
- Organizer
  第33回日本口腔腫瘍学会総会
- Place of Presentation
  奈良
- Year and Date
  2015-01-30
- Data Source
  KAKENHI-PROJECT-25462930
[Presentation] セツキシマブ耐性口腔扁平上皮癌細胞に対する治療の可能性2015
- Author(s)
  吉川桃子、莇生田整治、森川暁、臼田慎、宮下英高、河奈裕正、中川種昭、佐谷秀行、永野修
- Organizer
  第33回　日本口腔腫瘍学会　総会・学術大会
- Place of Presentation
  奈良
- Year and Date
  2015-01-30
- Data Source
  KAKENHI-PROJECT-26861579
[Presentation] 口腔癌細胞の腫瘍形成におけるCD44v-xCTの機能的役割2013
- Author(s)
  吉川　桃子
- Organizer
  第31回日本口腔腫瘍学会総会・学術大会
- Place of Presentation
  秋葉原
- Data Source
  KAKENHI-PROJECT-22592100
[Presentation] 口腔癌細胞の腫瘍形成におけるCD44v-xCTの機能的役割2013
- Author(s)
  吉川桃子, 永野修, 莇生田整治, 中川種昭, 河奈裕正, 佐谷秀行
- Organizer
  第31回日本口腔腫瘍学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22592100
[Presentation] Inhibition of xCT-mediated cystine transport supresses CD44v-expressing squamous cell carcinoma cells2012
- Author(s)
  吉川　桃子
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22592100
[Presentation] xCT シスチントランスポーターの阻害はCD44 バリアント陽性扁平上皮癌細胞の生体内における拡大を抑制する.2012
- Author(s)
  吉川桃子, 永野修, 土橋賢治, 莇生田整治, 中川種昭, 佐谷秀行
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22592100
[Presentation] xCT標的治療はCD44v陽性口腔扁平上皮癌細胞を選択的に死滅させる
- Author(s)
  吉川桃子, 莇生田整治, 河奈裕正, 中川種昭, 佐谷秀行
- Organizer
  第58回（社）日本口腔外科学会総会, 福岡, 2013.10.
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25462930
[Presentation] xCT inhibition depletes CD44v-expressing squamous cell carcinoma cells that are resistant to EGFR-targeted therapy
- Author(s)
  Momoko Yoshikawa, Osamu Nagano, Kenji Tsuchihashi, Seiji Asoda, Hiromasa Kawana, Taneaki Nakagawa, Hideyuki Saya
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25462930

1. ASODA Seiji (80296706)

# of Collaborated Projects: 8 results

# of Collaborated Products: 14 results
2. SAYA Hideyuki (80264282)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
3. 岡崎章悟 (20784044)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 森川暁 (00424169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 黄地健仁 (30803564)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 小澤宏之 (30327621)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. EINAGA YASUAKI (00322066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 相馬智也 (10624637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 片岡一則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. CABRAL Horacio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 持田祐希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshikawa Momoko 吉川 桃子

YOSHIKAWA MOMOKO 吉川 桃子

YOSHIKAWA Momoko 吉川 桃子

吉川 桃子 ヨシカワ モモコ

Research Projects

Research Products

Co-Researchers

PDXモデルを用いた局所進行・再発転移口腔癌に対する新たな治療戦略の考案Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

セロトニンシグナルを標的とした扁平上皮癌分化誘導療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Actionable遺伝子変異に基づく新たな口腔扁平上皮癌治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of CD44v-positive oral cancer stem cells using PDX model and establishment of novel drug therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of targetable genetic mutations and establishment of personalized therapy in standard therapy-resistant oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel treatment targeting cancer stromal cells in standard treatment-resistant oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of metabolic changes associated with cetuximab resistance in oral squamous cell carcinoma and designing of new treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the therapy for cetuximab-resistant oral squamous cell carcinoma cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Treatment sensitivity evaluation of oral squamous cell carcinoma based on the expression of a functional cancer stem cell marker CD44v

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New classification of oral squamous cell carcinoma based on the molecular expression profile controlling the epithelial mesenchymal transition and stem cell-like characteristics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)2016

Author(s)

Journal Title

Yoshikawa Momoko 吉川桃子

YOSHIKAWA MOMOKO 吉川桃子

YOSHIKAWA Momoko 吉川桃子

吉川桃子ヨシカワモモコ