SAMPETREAN OLTEA サンペトラオルテア

… Alternative Names

SAMPETREAN Oltea サンペトラオルテア

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Researcher Number	50571113
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, ヒト生物学-微生物叢-量子計算研究センター(信濃町), 特任教授
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, ヒト生物学-微生物叢-量子計算研究センター(信濃町), 特任教授 2021 – 2024: 慶應義塾大学, 医学部(信濃町), 講師 2023: 慶應義塾大学, Bio2Q, 特任教授 2018 – 2021: 慶應義塾大学, 医学部(信濃町), 助教 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 特任助教 2013 – 2015: 慶應義塾大学, 医学部, 特任助教 2010 – 2012: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Neurosurgery / Tumor biology Except Principal Investigator Broad Section I / Science and Engineering / Neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator 幹細胞 / 悪性脳腫瘍 / 脳腫瘍 / 癌幹細胞 / グリオーマ幹細胞 / ニッチ / がん幹細胞 / 癌 / 表現型可塑性 / 免疫応答 … More / 可塑性 / 自律性ニッチ / がん幹細胞ニッチ / 悪性グリオーマ / 膠芽腫 / グリオブラストーマ / 細胞・組織 / 遺伝子 … More Except Principal Investigator 発生・分化 / 癌 / 細胞・組織 / Aurora Bキナーゼ / 染色体動態 / Auroraキナーゼ / がん幹細胞 / 超解像イメージング / 異数体 / クロマチン高次構造 / 染色体不安定性 / 分子イメージング / ガンマ線イメージング / コンプトンカメラ / SPECT / 核医学 / CdTe / ガンマ線検出器 / バイオテクノロジー / 遺伝子 Less

脳腫瘍幹細胞の表現型可塑性及びフェノタイプ・スイッチの実態解明と克服方法の確立Principal Investigator
- Principal Investigator
  
  サンペトラオルテア
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Plastic regulation of chromosome dynamics in cancer
- Principal Investigator
  
  広田亨
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Japanese Foundation for Cancer Research
Evaluation and targeting of the autonomous niche of glioma stem cellsPrincipal Investigator
- Principal Investigator
  
  Sampetrean Oltea
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Novel and Interdisciplinary Application of Hard X-ray and Gamma-ray Detectors
- Principal Investigator
  
  Takahashi Tadayuki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Characterization and targeting strategies for the glioma stem cell nichePrincipal Investigator
- Principal Investigator
  
  SAMPETREAN OLTEA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Keio University
Analysis of metabloic characteristics of glioma stem cellsPrincipal Investigator
- Principal Investigator
  
  Sampetrean Oltea
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Keio University
Development of a novel anti-invasion therapy targeting the glioma stem cell/endothelial cell invasion complex
- Principal Investigator
  
  Saya Hideyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurosurgery
- Research Institution
  Keio University
Identification of key factors of glioblastoma tumorigenesisPrincipal Investigator
- Principal Investigator
  
  SAMPETREAN Oltea
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Keio University
Development of new strategies to overcome glioblastoma invasiveness and drug-resistance using a glioma stem cell model
- Principal Investigator
  
  SAYA Hideyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Keio University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] 5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy2023
- Author(s)
  Fukumura Masao、Nonoguchi Naosuke、Kawabata Shinji、Hiramatsu Ryo、Futamura Gen、Takeuchi Koji、Kanemitsu Takuya、Takata Takushi、Tanaka Hiroki、Suzuki Minoru、Sampetrean Oltea、Ikeda Naokado、Kuroiwa Toshihiko、Saya Hideyuki、Nakano Ichiro、Wanibuchi Masahiko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 10173-10173
- DOI
  10.1038/s41598-023-37296-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07177, KAKENHI-PROJECT-23H00410, KAKENHI-PROJECT-23K27715
[Journal Article] Dual-radionuclide in vivo imaging of micro-metastasis and lymph tract with submillimetre resolution2023
- Author(s)
  Yagishita Atsushi、Takeda Shin’ichiro、Ohnuki Kazunobu、Katsuragawa Miho、Sampetrean Oltea、Fujii Hirofumi、Takahashi Tadayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19464-19464
- DOI
  10.1038/s41598-023-46907-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18233, KAKENHI-PROJECT-22K07177, KAKENHI-PROJECT-20K16692, KAKENHI-WRAPUP-23H05414
[Journal Article] What can metabolites tell us about gliomas?2022
- Author(s)
  Sampetrean Oltea、Saya Hideyuki
- Journal Title
  
  Neuro-Oncology
  
  Volume: 24 Issue: 9 Pages: 1469-1470
- DOI
  10.1093/neuonc/noac128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07177
[Journal Article] Spatial Heterogeneity of Invading Glioblastoma Cells Regulated by Paracrine Factors2022
- Author(s)
  Chonan Yuta、Yamashita Tadahiro、Sampetrean Oltea、Saya Hideyuki、Sudo Ryo
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: - Issue: 13-14 Pages: 573-585
- DOI
  10.1089/ten.tea.2021.0168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07671, KAKENHI-PROJECT-19H04452, KAKENHI-PROJECT-19J22105, KAKENHI-PROJECT-22K07177
[Journal Article] Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis2022
- Author(s)
  Uetaki Megumi、Onishi Nobuyuki、Oki Yoshinao、Shimizu Takatsune、Sugihara Eiji、Sampetrean Oltea、Watanabe Takashi、Yanagi Hisano、Suda Kiyoshi、Fujii Hiroya、Kano Koichiro、Saya Hideyuki、Nobusue Hiroyuki
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 33 Issue: 9
- DOI
  10.1091/mbc.e21-12-0609
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07131, KAKENHI-PROJECT-22K07177, KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20K07600
[Journal Article] Heterogeneous Glioma Cell Invasion Under Interstitial Flow Depending on Their Differentiation Status2021
- Author(s)
  Namba Naoko、Chonan Yuta、Nunokawa Takehito、Sampetrean Oltea、Saya Hideyuki、Sudo Ryo
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 27 Issue: 7-8 Pages: 467-478
- DOI
  10.1089/ten.tea.2020.0280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07671, KAKENHI-PROJECT-19J22105, KAKENHI-PROJECT-19H04452
[Journal Article] N-cadherin upregulation mediates adaptive radioresistance in glioblastoma2021
- Author(s)
  Osuka Satoru、Zhu Dan、Zhang Zhaobin、Li Chaoxi、Stackhouse Christian T.、Sampetrean Oltea、Olson Jeffrey J.、Gillespie G. Yancey、Saya Hideyuki、Willey Christopher D.、Van Meir Erwin G.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 6
- DOI
  10.1172/jci136098
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07671, KAKENHI-PROJECT-20H00518
[Journal Article] Lactate Reprograms Energy and Lipid Metabolism in Glucose-Deprived Oxidative Glioma Stem Cells2021
- Author(s)
  Minami Noriaki、Tanaka Kazuhiro、Sasayama Takashi、Kohmura Eiji、Saya Hideyuki、Sampetrean Oltea
- Journal Title
  
  Metabolites
  
  Volume: 11 Issue: 5 Pages: 325-325
- DOI
  10.3390/metabo11050325
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07671, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20K09369, KAKENHI-PROJECT-20K09389, KAKENHI-PROJECT-21K19416, KAKENHI-PLANNED-18H05463
[Journal Article] Antifungal Agent Luliconazole Inhibits the Growth of Mouse Glioma-initiating Cells in Brain Explants2020
- Author(s)
  Nagashima Hideaki、Koike Naoyoshi、Yoshida Kazunari、Saya Hideyuki、Sampetrean Oltea
- Journal Title
  
  The Keio Journal of Medicine
  
  Volume: 69 Issue: 4 Pages: 97-104
- DOI
  10.2302/kjm.2020-0001-OA
- NAID
  130007960006
- ISSN
  0022-9717, 1880-1293
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07671
[Journal Article] 2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche2020
- Author(s)
  Koike Naoyoshi、Kota Ryuichi、Naito Yoshiko、Hayakawa Noriyo、Matsuura Tomomi、Hishiki Takako、Onishi Nobuyuki、Fukada Junichi、Suematsu Makoto、Shigematsu Naoyuki、Saya Hideyuki、Sampetrean Oltea
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 450-462
- DOI
  10.1038/s42003-020-01165-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07671, KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-20K16801, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-18K07771
[Journal Article] がん幹細胞とメタボロミクス2019
- Author(s)
  サンペトラ　オルテア、佐谷　秀行
- Journal Title
  
  医学のあゆみ
  
  Volume: 270(5) Pages: 417-423
- Data Source
  KAKENHI-PROJECT-19K07671
[Journal Article] Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model2018
- Author(s)
  Shibao S、Minami N、Koike N、Fukui N、Yoshida K、Saya H、Sampetrean O
- Journal Title
  
  Neuro-Oncology
  
  Volume: 20 Issue: 3 Pages: 343-354
- DOI
  10.1093/neuonc/nox170
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07124, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17J02715
[Journal Article] Tranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells2018
- Author(s)
  Harigai R、Sakai S、Nobusue H、Hirose C、Sampetrean O、Minami N、Hata Y、Kasama T、Hirose T、Takenouchi T、Kosaki K、Kishi K、Saya H、Arima Y
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 6069-6069
- DOI
  10.1038/s41598-018-24484-y
- NAID
  120006462320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07124
[Journal Article] Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival2018
- Author(s)
  Shiota M, Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, Suematsu M
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1561-1561
- DOI
  10.1038/s41467-018-03899-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01937, KAKENHI-PROJECT-15H04355, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-17K19614, KAKENHI-PROJECT-16K07124, KAKENHI-PROJECT-18J14396
[Journal Article] EGFR promotes glioma progression by regulating xCT and GluN2B-containing NMDA receptor signaling.2018
- Author(s)
  Suina K, Tsuchihashi K, Yamasaki J, Kamenori S, Shintani S, Hirata Y, Okazaki S, Sampetrean O, Baba E, Akashi K, Takahashi F, Takahashi K, Saya H, Nagano O.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 3874-3882
- DOI
  10.1111/cas.13826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-18K15215, KAKENHI-PROJECT-18K15223, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17H03583, KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K07124, KAKENHI-PROJECT-18J14396
[Journal Article] Endothelium-induced three-dimensional invasion of heterogeneous glioma initiating cells in a microfluidic coculture platform2017
- Author(s)
  Chonan Y、Taki S、Sampetrean O、Saya H、Sudo R
- Journal Title
  
  Integrative Biology
  
  Volume: 9 Issue: 9 Pages: 762-773
- DOI
  10.1039/c7ib00091j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07124
[Journal Article] Organotypic brain explant culture as a drug evaluation system for malignant brain tumors2017
- Author(s)
  Minami N、Maeda Y、Shibao S、Arima Y、Ohka F、Kondo Y、Maruyama K、Kusuhara M、Sasayama T、Kohmura E、Saya H、Sampetrean O
- Journal Title
  
  Cancer Medicine
  
  Volume: 6 Issue: 11 Pages: 2635-2645
- DOI
  10.1002/cam4.1174
- NAID
  120006373813
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07124, KAKENHI-PROJECT-17K10863, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17J02715, KAKENHI-PROJECT-15K10332
[Journal Article] The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)2016
- Author(s)
  Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H and Nagano O
- Journal Title
  
  Cancer Res
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253085
[Journal Article] Effects of fractionated radiation on murine glioma stem cell metabolism2016
- Author(s)
  Fujita S, Osuka S, Shibao S, Igarashi K, Soga T, Sampetrean O
- Journal Title
  
  Toho J Med
  
  Volume: in press
- NAID
  120006412373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861168
[Journal Article] The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)2016
- Author(s)
  Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H and Nagano O
- Journal Title
  
  Cancer Res
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861168
[Journal Article] Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression2015
- Author(s)
  Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR and Chen CC
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 112 Issue: 30 Pages: 112-130
- DOI
  10.1073/pnas.1501967112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253085, KAKENHI-PROJECT-26861168
[Journal Article] Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model2014
- Author(s)
  Saga I, Shibao S, Okubo J, Osuka S, Kobayashi Y, Yamada S, Fujita S, Urakami K, Kusuhara M, Yoshida K, Saya H, Sampetrean O
- Journal Title
  
  Neuro Oncol.
  
  Volume: 16 Issue: 8 Pages: 1048-1056
- DOI
  10.1093/neuonc/nou096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J06657, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-25253085, KAKENHI-PROJECT-26830082, KAKENHI-PROJECT-26861168
[Journal Article] Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model2014
- Author(s)
  Saga I, Shibao S, Okubo J, Osuka S, Kobayashi Y, Yamada S, Fujita S, Urakami K, Kusuhara M, Yoshida K, Saya H, Sampetrean O
- Journal Title
  
  Neuro-Oncology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700986
[Journal Article] Characteristics of glioma stem cells (Review, in press)2013
- Author(s)
  Sampetrean O
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249055
[Journal Article] IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells.2013
- Author(s)
  Osuka S, Sampetrean O, Saya H et al.
- Journal Title
  
  Stem Cells
  
  Volume: 31 Pages: 627-640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249055
[Journal Article] Characteristics of glioma stem cells2013
- Author(s)
  Sampetrean O and Saya H
- Journal Title
  
  Brain Tumor Pathol2013
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249055
[Journal Article] Characteristics of glioma stem cells2013
- Author(s)
  Sampetrean O
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700986
[Journal Article] Characteristics of glioma stem cells2013
- Author(s)
  Sampetrean O and Saya H
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 30(4) Issue: 4 Pages: 209-14
- DOI
  10.1007/s10014-013-0141-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700986
[Journal Article] Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells.2011
- Author(s)
  Sampetrean O, Saya H et al
- Journal Title
  
  Neoplasia
  
  Volume: 13 Pages: 784-791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249055
[Journal Article] Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells2011
- Author(s)
  Sampetrean O, Saya H, et al
- Journal Title
  
  Neoplasia
  
  Volume: 13 Pages: 784-791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] How chromosomal instability involves in glioma: perspectives from a syngenic model2023
- Author(s)
  趙民知, サンペトラ・オルテア, 音琴哲也, 加藤詩子, 佐谷秀行, 広田亨
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04996
[Presentation] 脳腫瘍幹細胞の不均一性と治療抵抗性2022
- Author(s)
  サンペトラ　オルテア
- Organizer
  第42回日本脳神経外科コングレス総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07177
[Presentation] がんの悪性形質獲得過程における染色体動態の可塑的制御とその意義2022
- Author(s)
  趙民知, 加藤詩子, サンペトラ・オルテア, 音琴哲也, 佐谷秀行, 広田亨
- Organizer
  第81回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04996
[Presentation] 酸化的リン酸化阻害剤による脳腫瘍幹細胞低酸素ニッチの制御法2022
- Author(s)
  サンペトラ　オルテア
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-22K07177
[Presentation] がん細胞における染色体動態の可塑的制御とその病理学的意義2022
- Author(s)
  趙民知, 加藤詩子, サンペトラオルテア, 音琴哲也, 佐谷秀行, 広田亨
- Organizer
  第45回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04996
[Presentation] 脳腫瘍幹細胞の不均一性と治療抵抗性2022
- Author(s)
  サンペトラ　オルテア
- Organizer
  第42回日本脳神経外科コングレス総会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05463
[Presentation] 酸化的リン酸化阻害剤による脳腫瘍幹細胞低酸素ニッチの制御法2022
- Author(s)
  サンペトラオルテア、佐谷秀行
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PLANNED-18H05463
[Presentation] CdTe SPECT を用いた担がんマウス微小リンパ節転移巣およびリンパ流路の２核種イメージング法の検証2021
- Author(s)
  3.柳下淳, 大貫和信, 武田伸一郎, 桂川美穂, 織田忠, 梅田泉, サンペトラオルテア, 藤井博史, 高橋忠幸
- Organizer
  第23回SNNS研究会学術集会（岐阜）
- Data Source
  KAKENHI-PLANNED-18H05463
[Presentation] 脳腫瘍幹細胞の低酸素応答と放射線抵抗性の克服2019
- Author(s)
  サンペトラ　オルテア，小池　直義，佐谷　秀行
- Organizer
  日本放射線腫瘍学会第32回学術大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05463
[Presentation] 脳内メタボライツによる正常神経幹細胞及び脳腫瘍幹細胞の制御2019
- Author(s)
  サンペトラ　オルテア、南　徳明、佐谷　秀行
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07671
[Presentation] Targeting adaptive pathways in glioma stem cells2018
- Author(s)
  Sampetrean O
- Organizer
  Taipei Pediatric Neuro-Oncology Symposium and Satellite Meetings for Targeted Research 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] グリオーマ幹細胞の放射線抵抗性の機序2018
- Author(s)
  サンペトラ　オルテア、佐谷　秀行
- Organizer
  第47回放射線による制癌シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] グリオーマ幹細胞の代謝柔軟性の克服戦略2018
- Author(s)
  サンペトラ　オルテア、南徳明、小池　直義、佐谷秀行
- Organizer
  第77回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] グリオーマ幹細胞の代謝特性及び微小環境への適応反応2018
- Author(s)
  サンペトラ　オルテア、南徳明、佐谷秀行
- Organizer
  第43回日本微小循環学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] 誘導型グリオーマ幹細胞モデルを用いた浸潤克服戦略の開発2017
- Author(s)
  サンペトラ・オルテア、佐谷　秀行
- Organizer
  第26回日本がん転移学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] 脳腫瘍幹細胞の低酸素応答2017
- Author(s)
  サンペトラ・オルテア、柴尾俊輔、南徳明、佐谷秀行
- Organizer
  第5回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] 脳腫瘍形成過程における代謝特性とその意義2017
- Author(s)
  サンペトラ・オルテア、佐谷　秀行
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] Metabolic characteristics of stem cells during glioma formation2016
- Author(s)
  Sampetrean O
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer
- Place of Presentation
  Maui (USA)
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861168
[Presentation] 脳腫瘍幹細胞における低酸素応答性、代謝不均一性と治療抵抗性2016
- Author(s)
  サンペトラ　オルテア
- Organizer
  第14回がんとハイポキシア研究会
- Place of Presentation
  岐阜グランドホテル、岐阜
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] Heterogeneity and plasticity in brain tumor stem cells2016
- Author(s)
  Sampetrean　O
- Organizer
  The Taiwan Pediatric Brain Tumor Symposium 2016 at TMUH
- Place of Presentation
  Taipei (Taiwan)
- Year and Date
  2016-04-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253085
[Presentation] Glioma stem cells: heterogeneity patterns and therapeutic challenges2016
- Author(s)
  Sampetrean O
- Organizer
  2nd Asian Central Nervous System Germ Cell Tumor Conference
- Place of Presentation
  Taipei (Taiwan)
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] 脳腫瘍幹細胞における代謝可塑性2016
- Author(s)
  サンペトラ　オルテア
- Organizer
  第４回がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島県、鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] 脳腫瘍幹細胞における不均一性、可塑性と治療抵抗性2016
- Author(s)
  サンペトラ　オルテア
- Organizer
  第25回定位放射線治療学会
- Place of Presentation
  ハイアットリージェンシー京都（京都府、京都）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] がん幹細胞の代謝不均一性及び可塑性2016
- Author(s)
  サンペトラ　オルテア
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07124
[Presentation] グリオーマ幹細胞の放射線後の細胞周期解析2015
- Author(s)
  サンペトラオルテア
- Organizer
  日本脳神経外科学会第74回学術総会
- Place of Presentation
  さっぽろ芸術文化の館（北海道札幌市）
- Year and Date
  2015-10-13
- Data Source
  KAKENHI-PROJECT-25253085
[Presentation] Crosstalk between initiating cells with different metabolism in a murine model of malignant glioma2014
- Author(s)
  2.Sampetrean O, Saga I, Shibao S, Okubo J, Osuka S, Onishi N, Fujita S, Saya H
- Organizer
  105 Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-04-07
- Data Source
  KAKENHI-PROJECT-26861168
[Presentation] Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model2014
- Author(s)
  Sampetrean O
- Organizer
  Keystone Symposia–x5 Tumor Metabolism
- Place of Presentation
  Whistler, Canada
- Year and Date
  2014-03-19
- Data Source
  KAKENHI-PROJECT-24700986
[Presentation] 脳腫瘍幹細胞における治療抵抗性のメカニズム2014
- Author(s)
  サンペトラ　オルテア
- Organizer
  第47 回ニューロ・オンコロジィの会
- Place of Presentation
  東京
- Year and Date
  2014-08-10
- Invited
- Data Source
  KAKENHI-PROJECT-25253085
[Presentation] 脳腫瘍幹細胞の代謝特性2014
- Author(s)
  サンペトラ　オルテア
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26861168
[Presentation] Integrated analysis identifies different metabolic signatures within both tumor-initiating cells and stem cells in a murine glioblastoma model2014
- Author(s)
  Sampetrean O, Saya H
- Organizer
  20th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Lake Tahoe, CA, USA
- Year and Date
  2014-07-21
- Data Source
  KAKENHI-PROJECT-26861168
[Presentation] Anti-invasion strategies in an induced cancer stem cell model of glioblastoma2012
- Author(s)
  Sampetrean O
- Organizer
  19th International Brain Tumor Research and Therapy Conference
- Place of Presentation
  Niagara, Canada
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] Invasion characteristics of tumor cells in a glioblastoma model of genetically modified neural stem cells2012
- Author(s)
  Sampetrean O
- Organizer
  103 Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, USA
- Year and Date
  2012-04-03
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] Anti-invasion strategies in an induced cancer stem cell model of glioblastoma2012
- Author(s)
  Sampetrean O
- Organizer
  19th International Brain Tumor Research and Therapy Conference
- Place of Presentation
  Niagara Falls, Canada
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-24700986
[Presentation] Anti-invasion strategies inan induced cancer stem cell model of glioblastoma2012
- Author(s)
  Sampetrean O
- Organizer
  19th International Brain Tumor Research and Therapy Conference
- Place of Presentation
  Niagara Falls, Canada
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] Invasion characteristics of tumor cells in a glioblastoma model of genetically modified neural stem cells2012
- Author(s)
  Sampetrean O
- Organizer
  103 Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24700986
[Presentation] Sampetrean O : Invasion characteristics of tumor cells in a glioblastoma model of genetically modified neural stem cells2012
- Author(s)
  Sampetrean O
- Organizer
  103 Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, USA
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-24700986
[Presentation] グリオーマ幹細胞モデルを用いた薬剤抵抗性克服2011
- Author(s)
  サンペトラオルテア
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] 悪性脳腫瘍幹細胞の浸潤能の解析2011
- Author(s)
  サンペトラオルテア、佐谷秀行
- Organizer
  第29回日本脳腫瘍学会
- Place of Presentation
  下呂温泉水明館(岐阜)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] New strategies in glioblastoma treatment-insights from the induced cancer stem cell (iCSC) model2011
- Author(s)
  Sampetrean O, Saya H
- Organizer
  Taipei VGH and NYMU Brain Tumor Symposium 2011
- Place of Presentation
  Taipei, Taiwan(招待講演)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] New strategies in glioblastoma treatment - insights from the induced cancer stem cell (iCSC) model2011
- Author(s)
  Sampetrean O
- Organizer
  Taipei VGH and NYMU Brain Tumor Symposium 2011
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] グリオーマ幹細胞モデルを用いた薬剤抵抗性克服2011
- Author(s)
  サンペトラオルテア、佐谷秀行
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] 悪性脳腫瘍幹細胞の浸潤能の解析2011
- Author(s)
  サンペトラオルテア
- Organizer
  第29回日本脳腫瘍学会
- Place of Presentation
  岐阜県下呂市
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] Analysis of invasion patterns in a model of malignant brain tumor2010
- Author(s)
  Sampetrean O
- Organizer
  The 18th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Travemunde, Germany
- Year and Date
  2010-05-16
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] 誘導癌幹細胞脳腫瘍モデルにおける腫瘍塊形成前の浸潤様式の解析2010
- Author(s)
  Sampetrean O
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] Analysis of invasion patterns in a model of malignant brain tumor2010
- Author(s)
  Sampetrean O
- Organizer
  The 18th International Conference on Brain Tum or Research and Therapy
- Place of Presentation
  Travemunde, Germany
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] Analysis of invasion patterns in an induced cancer stem cell model of malignant brain tumor2010
- Author(s)
  Sampetrean O
- Organizer
  AACR 101 Annual Meeting
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-22249055
[Presentation] 悪性脳腫瘍幹細胞の浸潤様式の解析
- Author(s)
  サンペトラ　オルテア
- Organizer
  第4回Vivid Workshop ー細胞機能と分子活性の多次元蛍光生体イメージング-
- Place of Presentation
  加賀温泉、石川県
- Data Source
  KAKENHI-PROJECT-25253085
[Presentation] Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model
- Author(s)
  Oltea Sampetrean
- Organizer
  Keystone Symposia - Tumor Metabolism
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-24700986

1. SAYA Hideyuki (80264282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. Takahashi Tadayuki (50183851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 武田伸一郎 (80553718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 織田忠 (10746522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 柳下淳 (20626676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 益子高 (30157200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 内山泰伸 (00435801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 能町正治 (90208299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 池田博一 (10132680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 広田亨 (50421368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 伊藤武彦 (90501106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 菱木貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 信末博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 高橋和久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 高橋史行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAMPETREAN OLTEA サンペトラ オルテア

SAMPETREAN Oltea サンペトラ オルテア

Research Projects

Research Products

Co-Researchers

脳腫瘍幹細胞の表現型可塑性及びフェノタイプ・スイッチの実態解明と克服方法の確立Principal Investigator

Principal Investigator

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Plastic regulation of chromosome dynamics in cancer

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Evaluation and targeting of the autonomous niche of glioma stem cellsPrincipal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Novel and Interdisciplinary Application of Hard X-ray and Gamma-ray Detectors

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Characterization and targeting strategies for the glioma stem cell nichePrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Analysis of metabloic characteristics of glioma stem cellsPrincipal Investigator

Principal Investigator

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Research Institution

Development of a novel anti-invasion therapy targeting the glioma stem cell/endothelial cell invasion complex

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of key factors of glioblastoma tumorigenesisPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Development of new strategies to overcome glioblastoma invasiveness and drug-resistance using a glioma stem cell model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual-radionuclide in vivo imaging of micro-metastasis and lymph tract with submillimetre resolution2023

Author(s)

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[Journal Article] What can metabolites tell us about gliomas?2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatial Heterogeneity of Invading Glioblastoma Cells Regulated by Paracrine Factors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis2022

SAMPETREAN OLTEA サンペトラオルテア

SAMPETREAN Oltea サンペトラオルテア

[Journal Article] Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival2018