Wakiya Taiichi 脇屋太一

Researcher Number	50571246
Other IDs	https://orcid.org/0000-0003-3681-7736
Affiliation (Current)	2025: 自治医科大学, 医学部, 講師 2025: 弘前大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2023: 弘前大学, 医学研究科, 客員研究員 2023: 自治医科大学, 医学部, 講師 2019 – 2022: 弘前大学, 医学部附属病院, 講師 2018: 弘前大学, 医学研究科, 助教 2017: 弘前大学, 医学部附属病院, 助教 2017: 弘前大学, 大学院医学研究科, 助教 2016: 弘前大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator 空間プロファイリング解析 / 代謝制御 / 免疫療法 / 膵臓 / 消化器癌 / 空間トランスクリプトーム解析 / 代謝免疫相互作用 / 肝硬変 / 合併症 / コラーゲン合成 … More / 線維化 / 免疫抑制剤 / 肝星細胞 / 肝移植 / 肝線維化 … More Except Principal Investigator 膵癌 / 膵癌間質 / ゲノム解析 / 遊離膵癌細胞 / 遺伝子座特異的クロマチン免疫沈降法 / プロテオミクス / CA19-9 / cfDNA / Kras変異遺伝子 / リキッドバイオプシー / Kras変異 / Liquid biopsy / Kras遺伝子変異 / 膵癌間質制御 / nab-paclitaxel / gemcitabine / 膵星細胞 / 膵臓癌 / 化学療法 / 間質制御 / 膵癌治療 / 細胞外マトリックス / hyaluronan / extracellular matrix / pancreatic cancer / 4-Methylumbelliferone / 4メチルウンベリフェロン / 免疫担当細胞 / γδT cell / γδT細胞 / CD44 / 抗癌剤細胞内移行 / ヒアルロン酸合成抑制 / 4-methylumbelliferone / 癌幹細胞 / ４メチルウンベリフェロン / ヒアルロン酸 / 間質 Less

膵癌における代謝免疫間相互関係のデジタル空間プロファイリングPrincipal Investigator
- Principal Investigator
  
  脇屋太一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University
Development of a novel method for detecting micro-pancreatic cancer using genome function analysis
- Principal Investigator
  
  Hakamada Kenichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hirosaki University
Establishment of Pancreatic Stellate Cell Inactivation by Cell Stromal Regulation to Conquer Pancreatic Cancer
- Principal Investigator
  
  Ishido Keinosuke
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hirosaki University
Development of Novel Therapies for Pancreatic Cancer by Regulating the Cancer Microenvironment Using Hyaluronan as a Target
- Principal Investigator
  
  Hakamada Kenichi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hirosaki University
The role of immunosuppressive drugs on hepatic stellate cells in liver graft and its application to the anti-fibrosis strategy in patients after liver transplantationPrincipal Investigator
- Principal Investigator
  
  Wakiya Taiichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Hirosaki University

All 2024 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Noninvasive Computed Tomography-Based Deep Learning Model Predicts In Vitro Chemosensitivity Assay Results in Pancreatic Cancer.2024
- Author(s)
  Kanda T, Wakiya T, Ishido K, Kimura N, Nagase H, Yoshida E, Nakagawa J, Matsuzaka M, Niioka T, Sasaki Y, Hakamada K.
- Journal Title
  
  Pancreas
  
  Volume: 53 Issue: 1 Pages: e55-e61
- DOI
  10.1097/mpa.0000000000002270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08746
[Journal Article] Postoperative long-term outcomes of acute normovolemic hemodilution in pancreatic cancer: A propensity score matching analysis.2024
- Author(s)
  Wakiya T, Ishido K, Kimura N, Nagase H, Kanda T, Kubota S, Fujita H, Takahashi Y, Yamamoto T, Chida K, Saito J, Hirota K, Hakamada K.
- Journal Title
  
  Oncol Lett
  
  Volume: 27 Issue: 5 Pages: 236-236
- DOI
  10.3892/ol.2024.14369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08746
[Journal Article] Development of a Biomarker-Based Scoring System Predicting Early Recurrence of Resectable Pancreatic Duct Adenocarcinoma.2022
- Author(s)
  Ishido K, Kimura N, Wakiya T, Nagase H, Hara Y, Kanda T, Fujita H, Hakamada K.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 29 Issue: 2 Pages: 1281-1293
- DOI
  10.1245/s10434-021-10866-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08746, KAKENHI-PROJECT-18K08695
[Journal Article] Heterogeneity of metabolic adaptive capacity affects the prognosis among pancreatic ductal adenocarcinomas2022
- Author(s)
  Kanda T, Wakiya T, Ishido K, Kimura N, Fujita H, Yoshizawa T, Goto S, Tatara Y, Kijima H, Hakamada K.
- Journal Title
  
  J Gastroenterol
  
  Volume: 57 Issue: 10 Pages: 798-811
- DOI
  10.1007/s00535-022-01898-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08746, KAKENHI-PROJECT-21K15396, KAKENHI-PROJECT-21H02700, KAKENHI-PROJECT-18K08695
[Journal Article] Effective dissection for rectal cancer with lateral lymph node metastasis based on prognostic factors and recurrence type2021
- Author(s)
  Morohashi Hajime、Sakamoto Yoshiyuki、Miura Takuya、Ichinohe Daichi、Umemura Kotaro、Akaishi Takanobu、Sato Kentaro、Kuwata Daisuke、Yamazaki Keisuke、Wakiya Taiichi、Hakamada Kenichi
- Journal Title
  
  International Journal of Colorectal Disease
  
  Volume: - Issue: 6 Pages: 1-11
- DOI
  10.1007/s00384-021-03870-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08668, KAKENHI-PROJECT-16K10587
[Journal Article] Eukaryotic initiation factor 2 signaling behind neural invasion linked with lymphatic and vascular invasion in pancreatic cancer2021
- Author(s)
  Wakiya Taiichi、Ishido Keinosuke、Kimura Norihisa、Nagase Hayato、Yoshizawa Tadashi、Morohashi Satoko、Fujita Hiroaki、Kanda Taishu、Tatara Yota、Saruwatari Junji、Kijima Hiroshi、Hakamada Kenichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 21197-21197
- DOI
  10.1038/s41598-021-00727-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07134, KAKENHI-PROJECT-20K09095, KAKENHI-PROJECT-21K08746, KAKENHI-PROJECT-21K15396
[Journal Article] Prediction of massive bleeding in pancreatic surgery based on preoperative patient characteristics using a decision tree.2021
- Author(s)
  Wakiya T, Ishido K, Kimura N, Nagase H, Kubota S, Fujita H, Hagiwara Y, Kanda T, Matsuzaka M, Sasaki Y, Hakamada K.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Issue: 11 Pages: e0259682-e0259682
- DOI
  10.1371/journal.pone.0259682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08746
[Journal Article] Essential updates 2018/2019: Current topics in the surgical treatment of pancreatic ductal adenocarcinoma2020
- Author(s)
  Ishido K, Hakamada K, Kimura N, Miura T, Wakiya T.
- Journal Title
  
  Ann Gastroenterol Surg
  
  Volume: 5 Issue: 1 Pages: 7-23
- DOI
  10.1002/ags3.12379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10587, KAKENHI-PROJECT-18K08695
[Journal Article] Combination therapy with gemcitabine and nab-paclitaxel for locally advanced unresectable pancreatic cancer2017
- Author(s)
  Saito Takeshi、Ishido Keinosuke、Kudo Daisuke、Kimura Norihisa、Wakiya Taiichi、Nakayama Yoshihito、Hakamada Kenichi
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 6 Issue: 6 Pages: 963-967
- DOI
  10.3892/mco.2017.1251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] CA19-9高値膵癌の悪性度に与える分子機構の解明（続報）2022
- Author(s)
  神田大周、脇屋太一、石戸圭之輔、木村憲央、長瀬勇人、桑田大輔、藤田博陽、須藤亜希子、市澤愛郁、袴田健一
- Organizer
  第77回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K08746
[Presentation] CA19-9高値膵癌の悪性度に関与する分子機構の解明2022
- Author(s)
  神田大周、脇屋太一、石戸圭之輔、木村憲央、長瀬勇人、桑田大輔、市澤愛郁、千田航平、藤田博陽、袴田健一
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08746
[Presentation] Enhancement of glycolytic system is associated with the malignant potential of PDAC with high CA19-9 levels2022
- Author(s)
  Kanda T, Wakiya T, Ishido K, Kimura N, Nagase H, Suto A, Fujita H, Saegusa Y, Tatara Y, Yoshizawa T, Goto S, Kijima H, Hakamada K
- Organizer
  第26回国際膵臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08746
[Presentation] 切除不能局所進行膵癌に対する conversion surgery のベストタイミング2021
- Author(s)
  石戸圭之輔、木村　憲央、脇屋　太一、長瀬　勇人、袴田　健一
- Organizer
  第52回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-21K08746
[Presentation] BRおよびUR膵癌に対するConversion surgeryの適応2020
- Author(s)
  石戸圭之輔、木村憲央、脇屋太一、長瀬勇人、小田切理、袴田健一
- Organizer
  第18回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] Stage I膵癌切除症例の長期成績と臨床的特徴2020
- Author(s)
  長瀬勇人、石戸圭之輔、木村憲央、脇屋太一、小田切理、久保田隼介、袴田健一
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] BRおよびUR膵癌の成績と集学的治療戦略の再考2020
- Author(s)
  石戸圭之輔、木村憲央、脇屋太一、長瀬勇人、小田切理、袴田健一
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] Impact of chemotherapy with gemcitabine and nab-paclitaxel in conversion surgery for UR-LA pancreatic cancer2019
- Author(s)
  Ishido K, Kimura N, Wakiya T, Nagase H, Hakamada K
- Organizer
  第31回日本肝胆膵外科学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] Pathological Impact on the Stroma After Preoperative Chemotherapy With nab-Paclitaxel and Gemcitabine for Pancreatic Cancer.2019
- Author(s)
  Ishido K, Kimura N, Wakiya T, Goto S, Yoshizawa T, Kijima H, Hakamada K
- Organizer
  The 7th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] HISTOPATHOLOGICAL IMPACT IN PANCREATIC CANCER STROMA INDUCED BY NAB-PACLITAXEL2018
- Author(s)
  石戸圭之輔、工藤大輔、木村憲央、脇屋太一、櫻庭真悟、内田知顕、袴田健一
- Organizer
  13th IHPBA World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08695
[Presentation] 切除不能局所進行膵癌におけるConversion surgeryをゴールとした治療戦略2018
- Author(s)
  石戸圭之輔、工藤大輔、木村憲央、脇屋太一、櫻庭真悟、袴田健一
- Organizer
  第118回日本外科学会
- Data Source
  KAKENHI-PROJECT-18K08695
[Presentation] HISTOPATHOLOGICAL IMPACT IN PANCREATIC CANCER STROMA INDUCED BY NAB-PACLITAXEL2018
- Author(s)
  石戸圭之輔、工藤大輔、木村憲央、脇屋太一、袴田健一
- Organizer
  49th American Pancreatic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08695
[Presentation] 膵癌間質中ヒアルロン酸を標的とした新規治療法の可能性2017
- Author(s)
  須藤亜希子、工藤　大輔、吉田　枝里、長瀬　勇人、三橋　佑人、脇屋　太一、木村　憲央、石戸圭之輔、袴田　健一
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] 膵癌間質中ヒアルロン酸を標的とした新規治療2017
- Author(s)
  須藤亜希子、工藤　大輔、吉田　枝里、長瀬　勇人、三橋　佑人、脇屋　太一、木村　憲央、石戸圭之輔、袴田　健一
- Organizer
  第72回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] ヒアルロン酸合成抑制剤を用いた間質制御による新たな膵癌治療法開発2016
- Author(s)
  吉田　枝里、工藤　大輔、長瀬　勇人、須藤亜希子、脇屋　太一、石戸圭之輔、豊木　嘉一、袴田　健一
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-16K10587
[Presentation] A novel tactics for the treatment of pancreatic adenocarinoma by targeting extracellular matrix2016
- Author(s)
  Suto A, Kudo D, Toyoki Y, Ishido K, Wakiya T, Nagase H, Yoshida T, Hakamada K
- Organizer
  20th meeting of the International Association of Pancreatology
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-08-04
- Data Source
  KAKENHI-PROJECT-16K10587

1. Hakamada Kenichi (30271802)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. Ishido Keinosuke (00436023)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
3. 木村憲央 (60436029)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
4. 三浦卓也 (30722136)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. 工藤大輔 (00587024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 柿崎育子 (80302024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 吉澤忠司 (70761071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ICHINOHE Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MOROHASHI Satoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUTSUMI Shinji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SARUWATARI Junji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 坂本義之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 諸橋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wakiya Taiichi 脇屋 太一

Research Projects

Research Products

Co-Researchers

膵癌における代謝免疫間相互関係のデジタル空間プロファイリングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel method for detecting micro-pancreatic cancer using genome function analysis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of Pancreatic Stellate Cell Inactivation by Cell Stromal Regulation to Conquer Pancreatic Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Novel Therapies for Pancreatic Cancer by Regulating the Cancer Microenvironment Using Hyaluronan as a Target

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of immunosuppressive drugs on hepatic stellate cells in liver graft and its application to the anti-fibrosis strategy in patients after liver transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Noninvasive Computed Tomography-Based Deep Learning Model Predicts In Vitro Chemosensitivity Assay Results in Pancreatic Cancer.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Postoperative long-term outcomes of acute normovolemic hemodilution in pancreatic cancer: A propensity score matching analysis.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Biomarker-Based Scoring System Predicting Early Recurrence of Resectable Pancreatic Duct Adenocarcinoma.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterogeneity of metabolic adaptive capacity affects the prognosis among pancreatic ductal adenocarcinomas2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effective dissection for rectal cancer with lateral lymph node metastasis based on prognostic factors and recurrence type2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Eukaryotic initiation factor 2 signaling behind neural invasion linked with lymphatic and vascular invasion in pancreatic cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of massive bleeding in pancreatic surgery based on preoperative patient characteristics using a decision tree.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Essential updates 2018/2019: Current topics in the surgical treatment of pancreatic ductal adenocarcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination therapy with gemcitabine and nab-paclitaxel for locally advanced unresectable pancreatic cancer2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] CA19-9高値膵癌の悪性度に与える分子機構の解明（続報）2022

Wakiya Taiichi 脇屋太一