Hayes Clair Nelson ＨａｙｅｓＣ．Ｎｅｌｓｏｎ

… Alternative Names

Hayes C.Nelson ヘイズクレアー・ネルソン

HAYES C.Nelson HAYES C.Nelson

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Researcher Number	50572327
Other IDs
Affiliation (Current)	2025: 広島大学, 医系科学研究科(医), 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 広島大学, 医系科学研究科(医), 准教授 2013: 広島大学, 医歯薬保健学研究院 (医), 特任講師 2013: 広島大学, 医歯薬保健学研究院(医), 特任講師 2012: 広島大学, 医歯薬保健学研究院, 特任講師
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 免疫学 / 医療 / 遺伝子 / ゲノム / ウィルス Except Principal Investigator 肥満 / モデル動物 / NASH / ヒト肝細胞キメラマウス / 脂肪肝 … More / 治療 / 線維化 / 成長ホルモン / ヒト肝細胞 / 脂肪化 Less

Study of NASH using human hepatocyte chimeric mouse and biopsy specimen
- Principal Investigator
  
  Chayama Kazuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hiroshima University
Tracking the emergence of escape mutants during triple therapy for hepatitis C virus infectionPrincipal Investigator
- Principal Investigator
  
  HAYES C.Nelson
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University

All 2024 2014 2013 Other

All Journal Article Presentation

[Journal Article] Multi-omics analysis of a fatty liver model using human hepatocyte chimeric mice.2024
- Author(s)
  Ichikawa A, Miki D, Hayes CN, Teraoka Y, Nakahara H, Tateno C, Ishida Y, Chayama K, Oka S.
- Journal Title
  
  Sci Rep.
  
  Volume: 14(1) Issue: 1 Pages: 3362-3362
- DOI
  10.1038/s41598-024-53890-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07416, KAKENHI-PROJECT-21H04817
[Journal Article] Ultradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin2014
- Author(s)
  Murakami, E. Imamura, M. Hayes, C. N. Abe, H. Hiraga, N. Honda, Y. Ono, A. Kosaka, K. Kawaoka, T. Tsuge, M. Aikata, H. Takahashi, S. Miki, D. Ochi, H. Matsui, H. Kanai, A. Inaba, T. McPhee, F. Chayama, K.
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 58 Issue: 4 Pages: 2105-2112
- DOI
  10.1128/aac.02068-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591397, KAKENHI-PROJECT-24790701, KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-26461008, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-26860536
[Journal Article] Interferon lambda 4 polymorphism effects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C2014
- Author(s)
  Nagaoki Y, Imamura M, Kawakami Y, Kan H, Fujino H, Fukuhara T, Kobayashi T, Ono A, Nakahara T, Naeshiro N, Urabe A, Yokoyama S, Miyaki D, Murakami E, Kawaoka T, Tsuge M, Hiramatsu A, Aikata H, Takahashi S, Hayes CN, Ochi H, Chayama K
- Journal Title
  
  Hepatology Research
  
  Volume: (印刷中) Issue: 14
- DOI
  10.1111/hepr.12336
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-26670383
[Journal Article] Emergence of resistant variants detected by ultra-deep sequencing after asuna- previr and daclatasvir combination therapy in HCV genotype 1 infected patients.2014
- Author(s)
  Kosaka K,Imamura M, Hayes CN, Abe H, Hiraga N, Yoshimi S, Murakami M, Kawaoka T, Tsuge M, Aikata H, Miki D, Ochi H, Matsui H, Kanai A, Inaba T, Chayama K
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790702
[Journal Article] interferon lambda 4/interleukin-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population2014
- Author(s)
  Ochi H, Miki D, Hayes CN, Abe H, Hayashida Y, Kubo M, Chayama K
- Journal Title
  
  Journal of General Virology
  
  Volume: 95巻 Issue: 6 Pages: 1297-306
- DOI
  10.1099/vir.0.060103-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-26860536, KAKENHI-PROJECT-221S0001
[Journal Article] HLA-DQB1*03 Confers Susceptibility to Chronic Hepatitis C in Japanese: A Genome-Wide Association Study.2013
- Author(s)
  Miki D, Ochi H, Takahashi A, Hayes CN, Urabe Y, Abe H, Kawaoka T, Tsuge M, Hiraga N, Imamura M, Kawakami Y, Aikata H, Takahashi S, Akuta N, Suzuki F, Ikeda K, Kumada H, Karino Y, Toyota J, Tsunoda T, Kubo M, Kamatani N, Nakamura Y, Chayama K.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 12 Pages: e84226-e84226
- DOI
  10.1371/journal.pone.0084226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790701, KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-25670369
[Journal Article] A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing2013
- Author(s)
  Abe H, Hayes CN, Hiraga N, Imamura M, Tsuge M, Miki D, Takahashi S, Ochi H, Chayama K
- Journal Title
  
  Am J Gastroenterol
  
  Volume: 108 Issue: 9 Pages: 1464-1472
- DOI
  10.1038/ajg.2013.205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790701, KAKENHI-PROJECT-24790702
[Journal Article] Changes in mRNA expression of hypothalamic appetite-regulating peptides during different phases of lactation in rats2013
- Author(s)
  Suzuki Y,Nakahara K, Maruyama K, Okame R, Ensho T, Inoue Y,Murakami N.
- Journal Title
  
  J Mol Endocrinol
  
  Volume: 52 Issue: 1 Pages: 97-109
- DOI
  10.1016/j.bbrc.2013.10.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380173, KAKENHI-PROJECT-24658247, KAKENHI-PROJECT-24790701, KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-24791023, KAKENHI-PROJECT-25670369
[Journal Article] Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice2013
- Author(s)
  Shi, N. Hiraga, N. Imamura, M. Hayes, C. N. Zhang, Y. Kosaka, K. Okazaki, A. Murakami, E. Tsuge, M. Abe, H. Aikata, H. Takahashi, S. Ochi, H. Tateno-Mukaidani, C. Yoshizato, K. Matsui, H. Kanai, A. Inaba, T. McPhee, F. Gao, M. Chayama, K.
- Journal Title
  
  Gut
  
  Volume: 62 Issue: 7 Pages: 1055-1061
- DOI
  10.1136/gutjnl-2012-302600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591397, KAKENHI-PROJECT-24790702, KAKENHI-PROJECT-25670369, KAKENHI-PLANNED-22118005
[Journal Article] Interleukin-28B polymorphisms and hepatitis C virusclearance2013
- Author(s)
  Chayama K, Hayes CN
- Journal Title
  
  Genome Medicine
  
  Volume: 5巻 Issue: 1 Pages: 6-6
- DOI
  10.1186/gm410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790702
[Journal Article] Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in hepatitis C virus genotype 1 infectedpatients
- Author(s)
  Kosaka K, Imamura M, Hayes CN, Abe H, Hiraga N, Yoshimi S, Murakami M, Kawaoka T, Tsuge M, Aikata H, Miki D, Ochi H, Matsui H, Kanai A, Inaba T, Chayama K
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790702
[Journal Article] Predictive value of the interferon lambda 4 polymorphism on outcome of telaprevir, pegylated interferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C
- Author(s)
  Fujino H, Imamura M, Nagaoki Y, Kawakami Y, Abe H, Hayes CN, Kan H, Fukuhara T, Kobayashi T, Masaki K, Ono A, Nakahara T, Honda Y, Naeshiro N, Urabe A, Yokoyama S, Miyaki D, Murakami E, Kawaoka T, Hiraga N, Tsuge M, Hiramatsu A, Hyogo H, Aikata H, Takahashi S, Miki D, Ochi H, Ohishi W, Chayama K
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790702
[Presentation] Early and late changes in gene expression profiles following infection with hepatitis B or C virus in human hepatocyte chimeric mice2013
- Author(s)
  Hayes CN, Akamatsu S, Tsuge M, Miki D, Hiraga N, Abe H, Imamura M, Tahahashi S, Ochi H, Chayama K
- Organizer
  The 64nd annual meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, U.S.A.
- Year and Date
  2013-11-04
- Data Source
  KAKENHI-PROJECT-24790702
[Presentation] Early and late changes in gene expression profiles following infection with hepatitis B or C virus in human hepatocyte chimeric mice2013
- Author(s)
  Hayes CN, Akamatsu S, Tsuge M, Miki D, Hiraga N, Abe H, Imamura M, Takahashi S, Ochi H, Chayama K
- Organizer
  The 64nd annual meeting of the American Asso- ciation for the Study of Liver Diseases
- Place of Presentation
  ワシントンDC、アメリカ
- Data Source
  KAKENHI-PROJECT-24790702

1. Chayama Kazuaki (00211376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 茶山弘美 (70572329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 三木大樹 (10584592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. ABE Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 松井啓隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 金井昭教

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 中原桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayes Clair Nelson Ｈａｙｅｓ Ｃ．Ｎｅｌｓｏｎ

Hayes C.Nelson ヘイズ クレアー・ネルソン

HAYES C.Nelson HAYES C.Nelson

Research Projects

Research Products

Co-Researchers

Study of NASH using human hepatocyte chimeric mouse and biopsy specimen

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tracking the emergence of escape mutants during triple therapy for hepatitis C virus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Multi-omics analysis of a fatty liver model using human hepatocyte chimeric mice.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ultradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interferon lambda 4 polymorphism effects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emergence of resistant variants detected by ultra-deep sequencing after asuna- previr and daclatasvir combination therapy in HCV genotype 1 infected patients.2014

Author(s)

Journal Title

Data Source

[Journal Article] interferon lambda 4/interleukin-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HLA-DQB1*03 Confers Susceptibility to Chronic Hepatitis C in Japanese: A Genome-Wide Association Study.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in mRNA expression of hypothalamic appetite-regulating peptides during different phases of lactation in rats2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin-28B polymorphisms and hepatitis C virusclearance2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in hepatitis C virus genotype 1 infectedpatients

Author(s)

Journal Title

Data Source

[Journal Article] Predictive value of the interferon lambda 4 polymorphism on outcome of telaprevir, pegylated interferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C

Author(s)

Journal Title

Data Source

[Presentation] Early and late changes in gene expression profiles following infection with hepatitis B or C virus in human hepatocyte chimeric mice2013

Author(s)

Organizer

Place of Presentation

Year and Date

Hayes Clair Nelson ＨａｙｅｓＣ．Ｎｅｌｓｏｎ

Hayes C.Nelson ヘイズクレアー・ネルソン