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Ohama Takashi  大浜 剛

… Alternative Names

OHAMA Takashi  大浜 剛

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Researcher Number 50579018
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-2998-6689
Affiliation (Current) 2025: 山口大学, 共同獣医学部, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 山口大学, 共同獣医学部, 准教授
2012 – 2014: 山口大学, 獣医学部, 准教授
2012: 山口大学, 共同獣医学部, 教授
2010 – 2011: 山口大学, 農学部, 准教授
Review Section/Research Field
Principal Investigator
Veterinary medical science / Basic Section 42020:Veterinary medical science-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Except Principal Investigator
Basic Section 42020:Veterinary medical science-related / Basic veterinary science/Basic zootechnical science
Keywords
Principal Investigator
がん / PP2A / SET / がん幹細胞 / タンパク質間結合 / MYC / NASH / タンパク質メチル化 / Protein phosphatase 2A / がん幹細胞性 … More / Protein Phosphatase 2A / 薬理学 / E2F1 / 比較腫瘍学 / 骨肉腫 / 筋繊維芽細胞 / 消化管 / HB-EGF / 大腸癌 / 筋線維芽細胞 / 脱リン酸化酵素 / Beclin 1 / リン酸化 / ホスファターゼ / オートファジー / アポトーシス / 細胞死 … More
Except Principal Investigator
Protein phosphatase 2A / 非アルコール性肝炎 / エピゲノム / タンパク質メチル化 / 線維芽細胞 / 受容体脱感作 / 炎症 / PAR / プロテアーゼ活性化受容体 / LmcMF / SmcMF / IMF / 筋線維芽細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (65 results)
  • Co-Researchers

    (6 People)
  •  非アルコール性脂肪肝炎の病態発症機構の解明

    • Principal Investigator
      佐藤 晃一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Yamaguchi University
  •  UndruggableなMYCを標的とした抗がん戦略創出のための基盤的研究Principal Investigator

    • Principal Investigator
      大浜 剛
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Yamaguchi University
  •  Understanding the pathogenic mechanism of NASH by focusing on the conversion of methionine metabolism to phosphorylation signals.Principal Investigator

    • Principal Investigator
      Ohama Takashi
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Yamaguchi University
  •  Stemness as a target for anti-cancer drug developmentPrincipal Investigator

    • Principal Investigator
      Ohama Takashi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Yamaguchi University
  •  Development of novel anti-cancer strategy targeting protein phosphatasesPrincipal Investigator

    • Principal Investigator
      Ohama Takashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Yamaguchi University
  •  Clarification of the role of myofibroblasts in cancer niche by development of cancer-tissue like organoidPrincipal Investigator

    • Principal Investigator
      Ohama Takashi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Veterinary medical science
    • Research Institution
      Yamaguchi University
  •  Mechanism of turnout switch for cell deathPrincipal Investigator

    • Principal Investigator
      OHAMA Takashi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Veterinary medical science
    • Research Institution
      Yamaguchi University
  •  The expression mechanism of protease activated receptors with inflammatory stimulations in intestinal myofibroblasts.

    • Principal Investigator
      SATO Koichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Yamaguchi University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Transcriptome analysis revealed that PME-1 suppresses inflammatory signaling, activates PI3K/Akt signaling, and promotes epithelial-mesenchymal transition2024

    • Author(s)
      Ikeda Shunta、Sato Koichi、Ohama Takashi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 692 Pages: 149148-149148

    • DOI

      10.1016/j.bbrc.2023.149148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ2341, KAKENHI-PROJECT-23K27077
  • [Journal Article] PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells2024

    • Author(s)
      Kohyanagi Naoki、Kitamura Nao、Ikeda Shunta、Shibutani Shusaku、Sato Koichi、Ohama Takashi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 300 Issue: 1 Pages: 105584-105584

    • DOI

      10.1016/j.jbc.2023.105584

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ2349, KAKENHI-PROJECT-22KJ2344, KAKENHI-PROJECT-23K27077
  • [Journal Article] The luciferase-based in vivo protein-protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction.2024

    • Author(s)
      Ando Sana、Tanaka Keiko、Matsumoto Maharu、Oyama Yuki、Tomabechi Yuri、Yamagata Atsushi、Shirouzu Mikako、Nakagawa Reiko、Okimoto Noriaki、Taiji Makoto、Sato Koichi、Ohama Takashi
    • Journal Title

      Journal of Biological Chemistry

      Volume: Apr. 6 Issue: 5 Pages: 107277-107277

    • DOI

      10.1016/j.jbc.2024.107277

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27077
  • [Journal Article] The protein level of the tumour-promoting factor SET is regulated by cell density2022

    • Author(s)
      Kohyanagi Naoki、Kitamura Nao、Tanaka Keiko、Mizuno Takuya、Fujiwara Nobuyuki、Ohama Takashi、Sato Koichi
    • Journal Title

      The Journal of Biochemistry

      Volume: 171 Issue: 3 Pages: 295-303

    • DOI

      10.1093/jb/mvab125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03151, KAKENHI-PROJECT-21K16434
  • [Journal Article] Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer2020

    • Author(s)
      Daisuke Fujimori, Jun Kinoshita, Takahisa Yamaguchi, Yusuke Nakamura, Katsuya Gunjigake, Takashi Ohama, Koichi Sato, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Tetsuo Ohta, Sachio Fushida
    • Journal Title

      BMC Cancer

      Volume: 20 Issue: 1 Pages: 1014-1014

    • DOI

      10.1186/s12885-020-07477-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06408, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-20H03151
  • [Journal Article] Perphenazine exerts antitumor effects on HUT78 cells through Akt dephosphorylation by protein phosphatase?2A2020

    • Author(s)
      Tsuji Shunya、Kohyanagi Naoki、Mizuno Takuya、Ohama Takashi、Sato Koichi
    • Journal Title

      Oncology Letters

      Volume: 21(2) Issue: 2 Pages: 113-113

    • DOI

      10.3892/ol.2020.12374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Journal Article] Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6.2020

    • Author(s)
      Nobuyuki Fujiwara, Shusaku Shibutani, Yusuke Sakai, Toshio Watanabe, Issei Kitabayashi, Hiroko Oshima, Masanobu Oshima, Hisashi Hoshida, Rinji Akada, Tatsuya Usui, Takashi Ohama*, Koichi Sato.
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 12 Pages: 4371-4380

    • DOI

      10.1111/cas.14662

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-20H03151, KAKENHI-PROJECT-18K06018, KAKENHI-PROJECT-18K16364
  • [Journal Article] Involvement of PP2A methylation in the adipogenic differentiation of bone marrow-derived mesenchymal stem cell2020

    • Author(s)
      Ikeda Shunta、Tsuji Shunya、Ohama Takashi、Sato Koichi
    • Journal Title

      The Journal of Biochemistry

      Volume: 168 Issue: 6 Pages: 643-650

    • DOI

      10.1093/jb/mvaa077

    • NAID

      40022458849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Journal Article] The multiple functions of protein phosphatase 62019

    • Author(s)
      Ohama Takashi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

      Volume: 1866 Issue: 1 Pages: 74-82

    • DOI

      10.1016/j.bbamcr.2018.07.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Journal Article] Efficacy of an anti-cancer strategy targeting SET in canine osteosarcoma2019

    • Author(s)
      TSUJI Shunya、OHAMA Takashi、NAKAGAWA Takayuki、SATO Koichi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 81 Issue: 10 Pages: 1424-1430

    • DOI

      10.1292/jvms.19-0311

    • NAID

      130007730596

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03915, KAKENHI-PROJECT-18J13124
  • [Journal Article] Distribution of SET/I2PP2A protein in gastrointestinal tissues.2019

    • Author(s)
      Umata K, Sakai Y, Ikeda S, Tsuji S, Kawasaki H, Ohama T, Sato K
    • Journal Title

      PloS One

      Volume: 14 Issue: 9 Pages: e0222845-e0222845

    • DOI

      10.1371/journal.pone.0222845

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05994, KAKENHI-PROJECT-17H03915
  • [Journal Article] Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis2018

    • Author(s)
      Enjoji Shuhei、Yabe Ryotaro、Tsuji Shunya、Yoshimura Kazuhiro、Kawasaki Hideyoshi、Sakurai Masashi、Sakai Yusuke、Takenouchi Hiroko、Yoshino Shigefumi、Hazama Shoichi、Nagano Hiroaki、Oshima Hiroko、Oshima Masanobu、Vitek Michael P.、Matsuura Tetsuya、Hippo Yoshitaka、Usui Tatsuya、Ohama Takashi、Sato Koichi
    • Journal Title

      Molecular Cancer Research

      Volume: 16 Issue: 3 Pages: 554-563

    • DOI

      10.1158/1541-7786.mcr-17-0393

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-17H03915, KAKENHI-PROJECT-15J07273, KAKENHI-PROJECT-16J01893, KAKENHI-PROJECT-16H06276
  • [Journal Article] A stable association with PME-1 may be dispensable for PP2A demethylation - implications for the detection of PP2A methylation and immunoprecipitation -2018

    • Author(s)
      Yabe R, Tsuji S, Mochida S, Ikehara T, Usui T, Ohama T*, Sato K
    • Journal Title

      FEBS Open Bio

      Volume: 8(9) Pages: 1486-1496

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Journal Article] Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor.2017

    • Author(s)
      Hideyoshi Kawasaki, Takuya Saotome, Tatsuya Usui, Takashi Ohama, Koichi Sato.
    • Journal Title

      Oncology Reports.

      Volume: 37 Issue: 5 Pages: 3128-3136

    • DOI

      10.3892/or.2017.5520

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14J06412, KAKENHI-PROJECT-15K14855, KAKENHI-PROJECT-15K14856
  • [Journal Article] The role of SET/I2PP2A in canine mammary tumors2017

    • Author(s)
      Kake Satoru、Tsuji Shunya、Enjoji Shuhei、Hanasaki Sayaka、Hayase Hiroshi、Yabe Ryotaro、Tanaka Yuiko、Nakagawa Takayuki、Liu Hao-Ping、Chang Shih-Chieh、Usui Tatsuya、Ohama Takashi、Sato Koichi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 4279-4279

    • DOI

      10.1038/s41598-017-04291-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Journal Article] Protein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome Degradation2015

    • Author(s)
      Yabe R, Miura A, Usui T, Mudrak I, Ogris E, Ohama T*, Sato K
    • Journal Title

      PLoS ONE

      Volume: 10(12) Issue: 12 Pages: e0145226-e0145226

    • DOI

      10.1371/journal.pone.0145226

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14856, KAKENHI-PROJECT-15J07273, KAKENHI-PROJECT-26850182
  • [Journal Article] Characterization of SET/I2PP2A Isoforms in Dogs2014

    • Author(s)
      Yabe R, Fujiwara N, Mizuno T, Usui T, Ohama T*, Sato K
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 76 Issue: 9 Pages: 1235-1240

    • DOI

      10.1292/jvms.14-0209

    • NAID

      130004432203

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Journal Article] Prostaglandin E2 inhibits proteinase-activated receptor 2-signal transduction through regulation of receptor internalization2013

    • Author(s)
      Komatsu H, Enjouji S, Ito A, Ohama T,Sato K
    • Journal Title

      J Vet Med Sci

      Volume: 75 Pages: 255-261

    • NAID

      130001879641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Journal Article] Prostaglandin E2 inhibits proteinase-activated receptor 2-signal transduction through regulation of receptor internalization.2013

    • Author(s)
      Komatsu H, Enjouji S, Ito A, Ohama T, Sato K.
    • Journal Title

      J Vet Med Sci

      Volume: 75 Pages: 255-261

    • NAID

      130001879641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Journal Article] Establishment of Mouse Intestinal Myofibroblast Cell Lines.2013

    • Author(s)
      Kawasaki H, Ohama T, Hori M, Sato K
    • Journal Title

      World J Gastroenterol

      Volume: 19 Pages: 2629-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Journal Article] Establishment of Mouse Intestinal Myofibroblast Cell Lines.2013

    • Author(s)
      Kawasaki H, Ohama T, Hori M, Sato K.
    • Journal Title

      World J Gastroenterol

      Volume: 19 Pages: 2683-2686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Journal Article] Trypsin inhibits lipopolysaccharide signaling in macrophages via toll-like receptor 4 accessory molecules2012

    • Author(s)
      Komatsu H, Shimose A, Shimizu T, Mukai Y, Kobayashi J, Ohama T, Sato K
    • Journal Title

      Life Sci

      Volume: 21;91(3-4) Issue: 3-4 Pages: 143-150

    • DOI

      10.1016/j.lfs.2012.06.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20228005, KAKENHI-PROJECT-22580334
  • [Journal Article] Trypsin inhibits lipopolysaccharide signaling in macrophages via toll-like receptor 4 accessory molecules2012

    • Author(s)
      Komatsu, H., A. Shimose, T. Shimizu, Y. Mukai, J. Kobayashi, T. Ohama, and K. Sato
    • Journal Title

      Life Sci

      Volume: 91 Pages: 143-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] The role of PME-1 as a PP2A methyl-esterase and a PP2A inhibitory protein2023

    • Author(s)
      Takashi Ohama
    • Organizer
      EMBO Signal regulation by protein phosphatases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27077
  • [Presentation] High cell density enhances the protein expression level of SET2022

    • Author(s)
      Kohyanagi N, Kitamura N, Tanaka K, Mizuno T, Fujiwara N, Ohama T, Sato K
    • Organizer
      The 6th International Symposium Association of Japan-Indonesia Veterinary Education 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Presentation] The role of PME-1 as a PP2A methyl-esterase and a PP2A inhibitory protein2022

    • Author(s)
      Takashi Ohama
    • Organizer
      FASEB The Protein Phosphatase Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19249
  • [Presentation] 腫瘍促進因子SETのタンパク質発現レベルは細胞密度により制御される2022

    • Author(s)
      幸柳尚規、北村菜央、田中慶子、藤原信行、大浜剛、佐藤晃一
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Presentation] SET/I2PP2A protein is up-regulated at high cell density2021

    • Author(s)
      Kohyanagi N, Kitamura N, Fujiwara N, Ohama T, Sato K
    • Organizer
      The 23rd Korea-Japan Joint Seminar on Pharmacology (23rd KJJSP)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Presentation] 細胞密度の上昇によりがん促進因子SETとSETBP1のタンパク質発現量の増加する2021

    • Author(s)
      幸柳尚規、北村菜央、田中慶子、藤原信行、大浜剛、佐藤晃一
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Presentation] The dual role of PME-1: PP2A inhibitory protein and methyl-esterase2020

    • Author(s)
      Takashi Ohama
    • Organizer
      The 14th International Conference on Protein Phosphatases
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Presentation] The role of PP2A inhibitory protein SET in cancer and its possibility as a drug target.2020

    • Author(s)
      大浜剛
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03151
  • [Presentation] Luciferase-based protein-protein interaction assay in living cells revealed SET dimerization to be essential for association with PP2A-B56 complex2019

    • Author(s)
      Tsuji S, Ikeda S, Shibutani S, Enjoji S, Ikeara S, Ohama T, Sato K
    • Organizer
      Europhosphatase2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Protein phosphatase 2A阻害タンパク質SETの骨肉腫における役割2019

    • Author(s)
      幸柳尚規、辻竣也、大浜剛、佐藤晃一
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Protein phosphatase 2Aとその阻害タンパク質PME-1のタンパク質間結合を制御する分子機構の解明2019

    • Author(s)
      松本真春、大山ゆき、大浜剛、佐藤晃一
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] 肺がん細胞A549においてPP2A複合体とその阻害タンパク質PME-1の果たす役割の解明2019

    • Author(s)
      池田俊太、大山ゆき、大浜剛、佐藤晃一
    • Organizer
      第162回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Synergistic anti-cancer effects of PME-1 suppression and p53 activation on A549 cells2019

    • Author(s)
      Shunta Ikeda, Yuki Oyama, Tsuji Shunya, Takashi Ohama, Koichi Sato
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] PP2A阻害タンパク質SETによる癌悪性化機構2019

    • Author(s)
      大浜剛
    • Organizer
      第92回日本生化学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Targeting PP2A inhibitory protein SET for cancer drug development2019

    • Author(s)
      Ohama T
    • Organizer
      4th TW-JP Bilateral Phosphatase Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] SET dimerization regulates PP2A/B56 association2018

    • Author(s)
      Tsuji S, Kake S, Enjoji S, Ohama T, Sato K
    • Organizer
      Workshop on Frontiers in Phosphatase Research and Drug Discovery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Stemness is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis2018

    • Author(s)
      Takashi Ohama
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Inhibition of SET dimerization restores activity of tumor suppressing phosphatase PP2A/B56α2018

    • Author(s)
      Shunya Tsuji, Shuhei Enjoji, Takashi Ohama, Koichi Sato
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] The role of SET in Gastric Cancer2018

    • Author(s)
      Ohama T
    • Organizer
      Workshop on Frontiers in Phosphatase Research and Drug Discovery
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] SETはPP2A活性阻害を介してE2F1を安定化することで、胃がんの幹細胞性の維持に関与する2018

    • Author(s)
      辻竣也、円城寺秀平、臼井達哉、大浜剛、佐藤晃一
    • Organizer
      第161回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] The role of SET/I2PP2A in canine mammary tumors2017

    • Author(s)
      Tsuji S, Kake S, Enjoji S, Ohama T, Sato K
    • Organizer
      Europhosphatase2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] SET/I2PP2A Is a Prognostic Marker and a Potential Therapeutic Target for Gastric Cancer.2017

    • Author(s)
      大浜剛、円城寺秀平、佐藤晃一
    • Organizer
      第8回日本プロテインホスファターゼ研究会
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] SET/I2PP2A Is a Prognostic Marker and a Potential Therapeutic Target for Gastric Cancer.2017

    • Author(s)
      Enjoji S, Ohama T, Sato K
    • Organizer
      Europhosphatase2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Regulation of Autophagy by Type2A Protein Phosphatases2017

    • Author(s)
      Ohama T, Fujiwara N, Sato K
    • Organizer
      Europhosphatase2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03915
  • [Presentation] Sphingosine-1-Phosphateは結腸癌微小環境において筋線維芽細胞の遊走を制御する2016

    • Author(s)
      川崎秀吉,馬田康司,硲彰一,鈴木伸明,永野浩昭,臼井達哉,大浜剛,佐藤晃一
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15K14856
  • [Presentation] 消化管の炎症・癌におけるタンパク質脱リン酸化酵素の役割2016

    • Author(s)
      大浜剛
    • Organizer
      第89回日本薬理学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15K14856
  • [Presentation] Protein Phosphatase Methyl Esterase PME-1 protects Protein Phosphatase 2A from ubiquitin/proteasome degradation2015

    • Author(s)
      Yabe R, Miura A, Sato K, Ohama T
    • Organizer
      Europhosphatase 2015
    • Place of Presentation
      Finland, Turku
    • Year and Date
      2015-06-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14856
  • [Presentation] Regulation of Beclin 1 association with Atg14L and autophagy by PP2A and DAPK32015

    • Author(s)
      Fujiwara N, Usui T, Sato K, Ohama T
    • Organizer
      Europhosphatase 2015
    • Place of Presentation
      Finland, Turku
    • Year and Date
      2015-06-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14856
  • [Presentation] 胃癌におけるPP2A阻害因子SETの役割の解明2014

    • Author(s)
      吉村和大、藤原信行、大島浩子、大島正伸、臼井達哉、大浜剛、佐藤晃一
    • Organizer
      第157回日本獣医学会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] Protein Phosphatase 6はBeclin 1-VPS34複合体を解離させる2013

    • Author(s)
      藤原信行、佐藤晃一、大浜剛
    • Organizer
      細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      淡路夢舞台国際会議場(淡路市)
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] The role of Protein Phosphatase 6 in mammalian autophagy2013

    • Author(s)
      Fujiwara N, Sato K, Ohama T
    • Organizer
      Europhosphatase 2013, Protein Phosphatase in Health and Disease
    • Place of Presentation
      Rehovot, Israel
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] PGE2 は PAR2 の内在化により PAR2 機能を阻害する2012

    • Author(s)
      小松浩之、円城寺秀平、大浜剛、佐藤晃一
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2012-11-23
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] マウス結腸筋線維芽細胞株の樹立とその有用性に関する検討2012

    • Author(s)
      川崎 秀吉、大浜 剛、佐藤 晃一
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      岩手大学(岩手)
    • Year and Date
      2012-09-16
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] マウス結腸筋線維芽細胞株の樹立とその有用性に関する検討2012

    • Author(s)
      川崎 秀吉、大浜 剛、佐藤 晃一
    • Organizer
      第154回日本獣医学会学術集会
    • Place of Presentation
      岩手大学
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] PGE2はPAR2の内在化によりPAR2機能を阻害する2012

    • Author(s)
      小松浩之、円城寺秀平、大浜剛、佐藤晃一
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] マウス結腸筋線維芽細胞の遊走に対するSphingosine-1 -Phosphate の影響2011

    • Author(s)
      川崎 秀吉、大浜 剛、佐藤 晃一
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪府立大学(大阪)
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] Typsin は CD14 の分解を介してマクロファージにおける LPS シグナルを阻害する2011

    • Author(s)
      小松浩之、円城寺秀平、大浜剛、佐藤晃一
    • Organizer
      第64回日本薬理学会西南部会
    • Place of Presentation
      KKR博多(福岡)
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-22580334
  • [Presentation] Protein Phosphatase Methyl Esterase PME-1 protects Protein Phosphatase 2A from ubiquitin/proteasome degradation

    • Author(s)
      Yabe R, Miura A, Sato K, Ohama T
    • Organizer
      Europhosphatase 2015
    • Place of Presentation
      Turku, Finland
    • Year and Date
      2015-06-24 – 2015-06-29
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] Protein Phosphatase Methyl Esterase PME-1 protects Protein Phosphatase 2A from ubiquitin/proteasome degradation

    • Author(s)
      Yabe R, Miura A, Sato K, Ohama T
    • Organizer
      11th International Conference on Protein Phosphatase
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2014-11-12 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] Regulation of Beclin 1 association with Atg14L and autophagy by PP2A and DAPK3

    • Author(s)
      Fujiwara N, Usui T, Sato K, Ohama T
    • Organizer
      Europhosphatase 2015
    • Place of Presentation
      Turku, Finland
    • Year and Date
      2015-06-24 – 2015-06-29
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] The Role of Protein Phosphatase 2A Associated Phospho-site of Beclin 1 on Autophagy

    • Author(s)
      Fujiwara N, Usui T, Sato K, Ohama T
    • Organizer
      11th International Conference on Protein Phosphatase
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2014-11-12 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-25660227
  • [Presentation] The role of PP2A inhibitor SET/I2PP2A in Gastric Cancer

    • Author(s)
      Enjoji S, Yoshimura K, Fujiwara N, Oshima H, Oshima M, Usui T, Sato K, Ohama T
    • Organizer
      11th International Conference on Protein Phosphatase
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2014-11-12 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-25660227
  • 1.  SATO Koichi (90205914)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 2.  大松 勉 (60455392)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  櫻井 優 (00747967)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  YAMAMOTO Masami
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  筆宝 義隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  渡辺 利雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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