Kozaka Takashi 小阪孝史

… Alternative Names

KOZAKA Takashi 小阪孝史

Less

Researcher Number	50579836
Other IDs	https://orcid.org/0009-0007-2580-2738
External Links
Affiliation (Current)	2025: 金沢大学, 疾患モデル総合研究センター, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 金沢大学, 疾患モデル総合研究センター, 助教 2011 – 2021: 金沢大学, 学際科学実験センター, 助教
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator σ-2受容体 / イメージング / vesamicol / σ受容体 / シグマ受容体 / ベサミコール / シグマ-2受容体 / 中枢神経系疾患 / イメージング剤 / イメージングプローブ … More / シグマ（σ）受容体 / BNCT / ホウ素含有イメージング剤 / 分子イメージング / 脳内σ-1受容体 / 選択的σ-2受容体リガンド … More Except Principal Investigator ベサミコール類似体 / SPECT / アセチルコリントランスポーター / 分子イメージング / アルツハイマー病 / 早期診断 / 放射性医薬品 / シグマ－１受容体 / OI5V / （+)-OI5V / vesamicol誘導体 / ストレス / σ-1受容体 / ストレス性疾患 / SPECT/CT / イメージング剤 / シグマ-1受容体 / ベサミコール / 光学分割 / アセチルコリントランスポータ / PET / ベサミコール類縁体 / PET用分子イメージング剤 / (-)-[11C]OMDV / アセチルコリントランスポーター(VAChT) / 早期診断薬 / ＰＥＴ / ＳＰＥＣＴ / コリン作動性神経系 / コリン作動性神経 Less

Development of CNS disease imaging probes targeting sigma-2 receptorsPrincipal Investigator
- Principal Investigator
  
  小阪孝史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Development of Novel Solid Tumor Imaging Agents Targeting the sigma ReceptorPrincipal Investigator
- Principal Investigator
  
  Kozaka Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Development of sigma-1 receptor imaging agent for early diagnosis of stress-related diseases
- Principal Investigator
  
  Shiba Kazuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Development of a new sigma-2 receptor ligand for imaging and BNCTPrincipal Investigator
- Principal Investigator
  
  Kozaka Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Development of the sigma-2 receptor imaging agent for the purpose of early detection and the proliferation potency diagnosis of the solid tumorPrincipal Investigator
- Principal Investigator
  
  Kozaka Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
The development of the presynaptic cholinergic nerve molecules imaging agent for early diagnosis of Alzheimer's disease
- Principal Investigator
  
  Shiba Kazuhiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Development of the Colin transporter imaging agent for early diagnosis of Alzheimer's disease
- Principal Investigator
  
  SHIBA Kazuhiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
The imaging study of sigma-1 receptor in the brain for the objective evaluation method of the disease caused by aging or stressPrincipal Investigator
- Principal Investigator
  
  KOZAKA Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] 125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia2023
- Author(s)
  Wakabayashi Hiroshi、Mori Hiroshi、Hiromasa Tomo、Akatani Norihito、Inaki Anri、Kozaka Takashi、Kitamura Yoji、Ogawa Kazuma、Kinuya Seigo、Taki Junichi
- Journal Title
  
  Journal of Nuclear Cardiology
  
  Volume: 30 Issue: 2 Pages: 653-661
- DOI
  10.1007/s12350-022-03064-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08047, KAKENHI-PROJECT-20K08102, KAKENHI-PROJECT-22K15841, KAKENHI-PROJECT-23K07152
[Journal Article] In vitro and in vivo evaluation of [125/123I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([125/123I]-OI5V) as a potential sigma-1 receptor ligand for SPECT.2021
- Author(s)
  Taiki Shigeno, Takashi Kozaka, Yoji Kitamura, Kazuma Ogawa, Junichi Taki, Seigo Kinuya, Kazuhiro Shiba.
- Journal Title
  
  Ann Nucl Med.
  
  Volume: 35 Issue: 2 Pages: 165-175
- DOI
  10.1007/s12149-020-01552-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08197, KAKENHI-PROJECT-20K07991, KAKENHI-PROJECT-20K08047, KAKENHI-PROJECT-20K08102, KAKENHI-PROJECT-19H03598
[Journal Article] (－)‐o‐[11C]methyl‐trans‐decalinvesamicol ((－)‐[11C]OMDV) as a PET ligand for the vesicular acetylcholine transporter2020
- Author(s)
  Miwa Daisuke、Kitamura Yoji、Kozaka Takashi、Shigeno Taiki、Ogawa Kazuma、Taki Junichi、Kinuya Seigo、Shiba Kazuhiro
- Journal Title
  
  Synapse
  
  Volume: 74 Issue: 11
- DOI
  10.1002/syn.22176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07991, KAKENHI-PROJECT-20K08102
[Journal Article] Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging2019
- Author(s)
  Ogawa Kazuma、Masuda Ryohei、Mishiro Kenji、Wang Mengfei、Kozaka Takashi、Shiba Kazuhiro、Kinuya Seigo、Odani Akira
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 18 Issue: 10 Pages: 31998-31999
- DOI
  10.1016/j.bmc.2019.03.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02668, KAKENHI-PROJECT-17K10355
[Journal Article] Development of a novel radiobromine-labeled sigma-1 receptor imaging probe2018
- Author(s)
  Kazuma Ogawa, Ryohei Masuda, Yoshiaki Mizuno, Akira Makino, Takashi Kozaka, Yoji Kitamura, Yasushi Kiyono, Kazuhiro Shiba, Akira Odani
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 61 Pages: 28-35
- DOI
  10.1016/j.nucmedbio.2018.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10355
[Journal Article] In vivo differences between two optical isomers of radioiodinated o-iodo-trans-decalinvesamicol for use as a radioligand for the vesicular acetylcholine transporter.2016
- Author(s)
  Uno I, KOzaka T, Miwa D, Kitamura Y, M.A Azim, Ogawa K, Taki J, Kinuya S, Shiba K.
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Issue: 1 Pages: 1-14
- DOI
  10.1371/journal.pone.0146719
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273, KAKENHI-PROJECT-15K09886
[Journal Article] Synthesis and evaluation of a new vesamicol analog o-[11C]methyl-trans-decalinvesamicol as a PET ligand for the vesicular acetylcholine transporter.2015
- Author(s)
  Kitamura Y., Kozaka T., Miwa D., Uno I., Azim M. A.-u., Ogawa K., Taki J., Kinuya S. and Shiba K.
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 30 Issue: 2 Pages: 122-129
- DOI
  10.1007/s12149-015-1039-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09886, KAKENHI-PROJECT-26293273, KAKENHI-PROJECT-26461847
[Journal Article] Regional brain imaging of vesicular acetylcholine transporter (VAChT) using o-[^<12>5I]iodo-trans-decalin vesamicol as a new potential imaging probe2014
- Author(s)
  Kozaka, T., Uno, I., Kitamura, Y., Miwa, D., Azim,MA., Ogawa, K. Shiba. K
- Journal Title
  
  Synapse
  
  Volume: Vol. 68 Issue: 3 Pages: 107-113
- DOI
  10.1002/syn.21720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813, KAKENHI-PROJECT-24591812
[Journal Article] Regional brain imaging of vesicular acetylcholine transporter (VAChT) using o-[125I]iodo-trans-decalinvesamicol as a new potential imaging probe.2014
- Author(s)
  Takashi Kozaka, Izumi Uno, Yoji Kitamura, Daisuke Miwa, Mohammad Anwar-ul Azim, Kazuma Ogawa, Kazuhiro Shiba.
- Journal Title
  
  Synapse
  
  Volume: 68 Pages: 107-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813
[Journal Article] Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT).2012
- Author(s)
  Takashi Kozaka, Izumi Uno, Yoji Kitamura, Daisuke Miwa, Kazuma Ogawa, Kazuhiro Shiba.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 20 Pages: 4936-4941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813
[Journal Article] Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT)2012
- Author(s)
  Kozaka, T., Uno, I., Kitamura, Y., Miwa, D., Ogawa, K., Shiba, K
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: Vol.20 Issue: 16 Pages: 4936-4941
- DOI
  10.1016/j.bmc.2012.06.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813, KAKENHI-PROJECT-24591812
[Presentation] 新規σ-2受容体リガンドMILVの開発とイメージング剤としての基礎評価2024
- Author(s)
  小阪孝史, 北村陽二, 小川数馬, 木村寛之
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K07152
[Presentation] Dynamic Expression of Myocardial Sigma-1 Receptor in Doxorubicin-Induced Cardiomyopathy using Radioiodine Labeled 2-[4- (2iodophenyl)piperidino]cyclopentanol (OI5V) Imaging2023
- Author(s)
  Chen Z, Wakabayashi H, Mori H, Hiromasa T, Zhang X, Kozaka T, Ogawa K, Kinuya S, Taki J
- Organizer
  Congress of European Association of Nuclear Medicine 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07152
[Presentation] Positive Protective Effects of Sigma-1 Receptor Stimulation with Fluvoxamine after Myocardial Ischemia and Reperfusion in Rat2023
- Author(s)
  Zhang X, Wakabayashi H, Mori H, Hiromasa T, Chen Z, Kozaka T, Ogawa K, Kinuya S, Taki J
- Organizer
  Congress of European Association of Nuclear Medicine 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07152
[Presentation] 125I-Labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) imaging Visualized Augmented Sigma-1 Receptor Expression by Depending on the Severity of Myocardial Ischemia2022
- Author(s)
  Hiroshi Wakabayashi, Junichi Taki, Hiroshi Mori, Tomo Hiromasa, Norihito Akatani, Anri Inaki, Takashi Kozaka, Yoji Kitamura, Kazuma Ogawa, Seigo Kinuya
- Organizer
  第13回世界核医学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07991
[Presentation] Development of PET / SPECT probes for Vesicular acetylcholine transporter (VAChT) imaging2021
- Author(s)
  小阪孝史
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07991
[Presentation] ストレス負荷マウスにおけるストレス強度と局所脳血流量の関係2020
- Author(s)
  野坂朋代、池田朝海、北村陽二、小阪孝史、小川数馬、柴和弘
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] VAChTイメージング剤(OIDV)の脳内移行性におけるP糖蛋白の影響2019
- Author(s)
  小阪孝史, 髙橋茉衣夏, 北村陽二, 池田朝海, 小川数馬, 柴和弘
- Organizer
  日本薬学会第139年会（幕張メッセ，千葉）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] (+)-[125/123I]OI5Vのシグマ-1受容体イメージング剤としての基礎的評価2019
- Author(s)
  高橋茉衣夏、小阪孝史、北村陽二、池田朝海、小川数馬、柴和弘
- Organizer
  第59回日本核医学学術総会
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] ストレス負荷マウスにおけるコリン作動性神経系(VAChT)の変化2019
- Author(s)
  柴和弘, 髙橋茉衣夏, 北村陽二, 小阪孝史, 池田朝海, 小川数馬
- Organizer
  日本薬学会第139年会（幕張メッセ，千葉）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] [125I]OI5Vによる15q重複Tgマウス（自閉症マウス）の脳内σ-1受容体密度測定2019
- Author(s)
  髙橋茉衣夏, 小阪孝史, 北村陽二, 池田朝海, 小川数馬, 柴和弘
- Organizer
  日本薬学会第139年会（幕張メッセ，千葉）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] Usefulness of radioiodinated 2-[4-(2-iodophenyl)piperidino]cyclopentanol(OI5V) for early diagnosing neurodegenerative disorder caused by stress.2018
- Author(s)
  Shigeno T, Takahashi M, Kozaka T, Kitamura Y, Kamide M, Hamamoto M, Yoshida K, Ogawa K, Shiba K.
- Organizer
  12th World Congress of the World Federation of Nuclear Medicine and Biology. （Melbourne, Australlia）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] ストレス性精神疾患の早期診断用新規イメーイング剤の開発2018
- Author(s)
  高橋茉衣夏、茂野泰貴、小阪孝史、北村陽二、上出茉歩、濱本萌凪、吉田楓、小川数馬、柴　和弘
- Organizer
  第58回日本核医学会学術総会（沖縄コンベンションセンター，沖縄）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] ヒト染色体15番長腕重複モデルマウスのストレス負荷によるドーパミン受容体への影響2017
- Author(s)
  北嶋祥太郎，小澤梓，北村陽二，小阪孝史，茂野泰貴，小川数馬，柴　和弘
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] [123I]OI5Vの新規シグマ-1受容体イメージング剤としての評価2017
- Author(s)
  茂野泰貴、小阪孝史、北村陽二、小川数馬、柴　和弘
- Organizer
  第15回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2017)
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] 5員環を有するvesamicol類縁体のシグマ-1受容体イメージング剤としての基礎的評価2017
- Author(s)
  茂野泰貴，小阪孝史，北村陽二，石山史奈，小川数馬，柴　和弘
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 環サイズの異なるvesamicol類縁体の小胞アセチルコリントランスポーター及びシグマ受容体との構造活性相関2017
- Author(s)
  石山史奈，小阪孝史，高橋茉衣夏，北村陽二，茂野泰貴，小川数馬，柴　和弘
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 1,2環サイズの異なるvesamicol類縁体の小胞アセチルコリントランスポーター及びシグマ受容体との構造活性相関2017
- Author(s)
  石山　史奈、小阪　孝史、高橋　茉衣夏、北村　陽二、茂野　泰貴、小川　数馬、柴　和弘
- Organizer
  日本薬学会　第137年会
- Place of Presentation
  仙台国際センター　(仙台市)
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] Characteristics of 2-[4-(2-iodophenyl)piperidino]cyclopenntanon (OI5V) as a new siguma-1 receptor imaging agent.2017
- Author(s)
  Taiki Shigeno, Takashi Kozaka, Yoji Kitamura, Rina Ishiyama, Kazuma Ogawa, Kazuhiro Shiba
- Organizer
  SNMMI 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] 新規SPECT用シグマ-1受容体イメージング剤の開発研究2017
- Author(s)
  茂野泰貴、小阪孝史、北村陽二、小川数馬、柴和弘
- Organizer
  第12回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] Characteristics of 2-[4-(2-iodophenyl)piperidino]cyclopentanol(OI5V) as a new sigma-1 receptor imaging agent2017
- Author(s)
  Taiki Shigeno, Takashi Kozaka, Yoji Kitamura, Rina Ishiyama, Kazuma Ogawa, Kazuhiro Shiba
- Organizer
  2017 SNMMI 64th annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] 新規SPECT用シグマ-1受容体イメージング剤の開発研究2017
- Author(s)
  茂野泰貴、小阪孝史、北村陽二、小川数馬、柴　和弘
- Organizer
  日本分子イメージング学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] In vitro Evaluation of meta-bromo benzovesamicol (MBBzV) as a Potential Vesicular Acetylcholine Transporter (VAChT) Imaging Probe2016
- Author(s)
  Azim MA, Kozaka T, Uno I, Miwa D, Kitamura Y, Shiba K.
- Organizer
  The 2nd Asian Nuclear Medicine Academic Forum 2016
- Place of Presentation
  Shanghai, China
- Year and Date
  2016-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] In vitro evaluation meta-bromo benzovesamicol as PET VAChT imaging Probe.2016
- Author(s)
  Azim MA, Kozaka T, Uno I, Miwa D, Kitamura Y, Shiba K.
- Organizer
  he 2nd Asian Nuclear Medicine Academic Forum 2016,(ANMAF 2016)
- Place of Presentation
  Shanghai, China.
- Year and Date
  2016-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] SPECT用σ-2受容体イメージング剤[123I]PIDVの開発研究2016
- Author(s)
  小阪孝史、緩詰沙耶、茂野泰貴、北村陽二、小川数馬、川井恵一、絹谷清剛、柴和弘
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 有機合成化学を基盤とした分子イメージング研究2016
- Author(s)
  小阪孝史
- Organizer
  平成28年度北信越若手有機合成化学若手研究会
- Place of Presentation
  金沢
- Year and Date
  2016-04-02
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] Development of a radiobromine-labeled compound as a sigma receptor ligand for tumor imaging2016
- Author(s)
  Mizuno Y, Makino A, Masuda R, Kozaka T, Kitamura Y, Kiyono Y, Shiba K, Odani A
- Organizer
  2016 SNMMI 63th annual meeting
- Place of Presentation
  Sangiego, USA
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] Vesamicolを母核とする新規σ-2受容体選択的リガンドの開発研究2016
- Author(s)
  小阪孝史, 柴山怜子, 稲垣冬彦, 向智里, 北村陽二, 小川数馬, 柴和弘
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 111In標識八臭素化ポルフィリン誘導体の腫瘍イメージング剤としての開発研究2016
- Author(s)
  北村陽二、小川数馬、小阪孝史、茂野泰貴、北嶋祥太郎、石山史奈、中島美由紀、御舩正樹、川井恵一、絹谷清剛、斎藤寛、柴和弘
- Organizer
  第11回日本分子イメージング学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-05-29
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] Evaluation of radiolabeled o-bromo- decalinvesamicol (OBDV) as a PET ligand for the Vesicular Acetylcholine Transporter (VAChT)2014
- Author(s)
  Azim, MA., Kozaka, T., Uno, I., Miwa, D., Kitamura, Y., Ogawa, K., Kawai, K., Makino, A., Kiyono, Y and Shiba, K
- Organizer
  International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology
- Place of Presentation
  ユアーズホテルフクイ(福井市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] PET用イメージング剤[11C]OMDVの光学分割と動態評価2014
- Author(s)
  三輪大輔、小阪孝史、北村陽二、Mohammad A. Azim,　黒宮里紗、緩詰沙耶、小川数馬、川井恵一、柴　和弘
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] 新規σ－２受容体イメージング剤ＰＩＤＶの開発研究2014
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Mohammad A. Azim、黒宮里紗、北村陽二、小川数馬、川井恵一、柴和弘
- Organizer
  第9回日本分子イメージング学会学術集会
- Place of Presentation
  大阪府豊中市・千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-23791400
[Presentation] Evaluation of radiolabeled o-bromo-decalinvesamicol (OBDV) as a PET ligand for the Vesicular Acetylcholine Transporter (VAChT).2014
- Author(s)
  Mohammad Anwar-ul Azim , Takashi Kozaka, Izumi Uno, Daisuke Miwa, Yoji Kitamura, Kazuma Ogawa, Keiichi Kawai, Akira Makino, Yasushi Kiyono, Kazuhiro Shiba.
- Organizer
  International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology.
- Place of Presentation
  ユアーズホテルフクイ、福井市、福井県
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] Introduction of radiobromine labeled decalinvesamicol analogue as a new and promising PET vesicular acetylcholine transporter (VAChT) imaging probe.2014
- Author(s)
  Mohammad Anwar-ul Azim, Takashi Kozaka, Izumi Uno, Daisuke Miwa, Yoji Kitamura, Kazuma Ogawa, Keiichi Kawai, Yasushi Kiyono, Kazuhiro Shiba.
- Organizer
  SNMMI 61th annual meeting.
- Place of Presentation
  Louis Convention Center, St. Louis. USA.
- Year and Date
  2014-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] 新規σ-2受容体イメージング剤PIDVの開発研究2014
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Mohammad A. Azim、黒宮里紗、北村陽二、小川数馬川井恵一、柴和弘
- Organizer
  日本分子イメージング学会第9回学会総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-23791400
[Presentation] The development of potential vesicular acetylcholine transporter (VAChT) PET imaging probes2013
- Author(s)
  Kozaka T, Miwa D, Uno I, Kitamura Y, Azim MA, Ogawa K, Kinuya S, Kawai K, Shiba K
- Organizer
  2013 SNMMI 60th annual meeting. Vancouber Convention Centre
- Place of Presentation
  Vancouber, BC, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] アルツハイマー病の早期診断を目的とした新規PET用VAChTイメージング剤[^<11>C]OMDVの合成とin vivo評価2013
- Author(s)
  小阪孝史、三輪大輔、鵜野いずみ、北村陽二、Mohammad Anwer-ul AZIM,川村和紀、小川数馬、川井恵一、柴和弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] In vivo evaluation of radioiodinated o-iodo-trans-decalinvesamicol（ＯＩＤＶ） as a vesicular acetylcholine transporter (VAChT) imaging agent.2013
- Author(s)
  Uno I, Kozaka T, Kitamura Y, Miwa D, Azim MA, Ogawa K, Kawai K, Taki J, Kinuya S, Shiba K.
- Organizer
  2013 SNMMI 60th annual meeting.
- Place of Presentation
  Vancouber Convention Centre, Vancouber, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] The development of potential vesicular acetylcholine transporter (VAChT) PET imaging probes.2013
- Author(s)
  Kozaka T, Miwa D, Uno I, Kitamura Y, Azim MA, Ogawa K, Kinuya S, Kawai K, Shiba K.
- Organizer
  2013 SNMMI 60th annual meeting.
- Place of Presentation
  Vancouber Convention Centre, Vancouber, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] VAChTイメージング用[125I]OIDVのジアステレオマー分離と in vivo 脳内動態変化2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Azim Mohammad A、小川数馬、川井恵一、柴和弘.
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサ、静岡市、静岡県
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] In vivo evaluation of radioiodinated o-iodo-trans- decalinvesamicol(OIDV)as a vesicular acetylcholine transporter (VAChT) imaging agent2013
- Author(s)
  Uno I, Kozaka T, Kitamura Y, Miwa D, Azim MA, Ogawa K, Kawai K, Taki J, Kinuya S, Shiba K
- Organizer
  2013 SNMMI 60th annual meeting
- Place of Presentation
  Vancouber Convention Centre, Vancouber, BC, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] アルツハイマー病の早期診断を目的とした新規PET用VAChTイメージング剤[11C]OMDVの合成とin vivo 評価2013
- Author(s)
  小阪孝史、三輪大輔、鵜野いずみ、北村陽二、Mohammad Anwer-ul AZIM,　川村和紀、小川数馬、川井恵一、柴　和弘
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 脳内小胞アセチルコリントランスポーター(VAChT)のPETイメージングプローブ[^<11>C]OMDVの開発2013
- Author(s)
  三輪大輔,小阪孝史,鵜野いずみ,北村陽二, Azim Mohammad A.,河村和紀,小川数馬,川井恵一,柴和弘
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサおよび三保園ホテル(静岡市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 脳内小胞アセチルコリントランスポーター（VAChT）のPETイメージングプローブ[11C]OMDVの開発,2013
- Author(s)
  三輪大輔, 小阪孝史, 鵜野いずみ, 北村陽二, Azim Mohammad A., 河村和紀, 小川数馬, 川井恵一, 柴和弘,
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサ、静岡市、静岡県
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] OIDVのジアステレオマー分離とその選択的VAChTイメージング剤としての評価2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Mohammad Anwer-ul AZIM,小川数馬、川井恵一、柴和弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] VAChTイメージング用[^<125>I]OIDVのジアステレオマー分離とin vivo脳内動態変化2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Azim Mohammad A、小川数馬、川井恵一、柴和弘
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサおよび三保園ホテル(静岡市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] OIDVのジアステレオマー分離とその選択的VAChTイメージング剤としての評価2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Mohammad Anwer-ul AZIM,　小川数馬、川井恵一、柴　和弘
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] PET用VAChTイメージング剤の開発研究2012
- Author(s)
  小阪孝史,三輪大輔,鵜野いずみ,北村陽二,Azim Mohammad Anwar-ul,小川数馬,川井恵一,絹谷清剛,柴和弘
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都テルサ,京都市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] PET用VAChTイメージング剤の開発研究2012
- Author(s)
  小阪孝史，三輪大輔，鵜野いずみ，北村陽二，Azim Mohammad Anwar-ul，小川数馬，川井恵一, 絹谷清剛, 柴和弘
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都テルサ（京都市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 前シナプスコリン作動性神経描画用新規VAChTイメージング剤の開発2012
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、道関美祐、小川数馬、川井恵一、河原　栄、柴　和弘、
- Organizer
  第7回日本分子イメージング学会総会・学術大会
- Place of Presentation
  アクトシティ浜松(浜松市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 前シナプスコリン作動性神経描画用新規VAChTイメージング剤の開発2012
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、道関美祐、小川数馬、川井恵一、河原栄、柴和弘
- Organizer
  第7回日本分子イメージング学会総会・学術大会
- Place of Presentation
  アクトシティ浜松(浜松市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] Vesamicol誘導体を用いた新規VAChTイメージング剤の開発2011
- Author(s)
  小阪孝史,鵜野いずみ,北村陽二,小川数馬,川井恵一,絹谷清剛,柴和弘
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  筑波市
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] VAChTイメージング用新規プローブの合成とその評価2011
- Author(s)
  鵜野いずみ,小阪孝史,北村陽二,小川数馬,川井恵一,絹谷清剛,柴和弘
- Organizer
  第11回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都市
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 新規σ-2受容体イメージング剤PIDVの開発研究
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Azim A. M.、黒宮里紗、北村陽二、小川数馬、川井恵一、柴和弘
- Organizer
  第9回日本分子イメージング学会総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-05-22 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 新規vesamicol類縁体PIDVのσ-2受容体イメージング剤としての可能性
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、北村陽二、Azim A. M.、小川数馬、川井恵一、柴和弘
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] SPECT用シグマ-2受容体イメージング剤の合成と基礎的評価
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Azim A. M.、黒宮里紗、北村陽二、小川数馬、川井恵一、絹谷清剛、柴和弘
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26860987

1. SHIBA Kazuhiro (40143929)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. KITAMURA Yoji (10368483)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
3. 横山茂 (00210633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKI Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 絹谷清剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 小川数馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Kozaka Takashi 小阪 孝史

KOZAKA Takashi 小阪 孝史

Research Projects

Research Products

Co-Researchers

Development of CNS disease imaging probes targeting sigma-2 receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Novel Solid Tumor Imaging Agents Targeting the sigma ReceptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of sigma-1 receptor imaging agent for early diagnosis of stress-related diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new sigma-2 receptor ligand for imaging and BNCTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the sigma-2 receptor imaging agent for the purpose of early detection and the proliferation potency diagnosis of the solid tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of the presynaptic cholinergic nerve molecules imaging agent for early diagnosis of Alzheimer's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the Colin transporter imaging agent for early diagnosis of Alzheimer's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The imaging study of sigma-1 receptor in the brain for the objective evaluation method of the disease caused by aging or stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro and in vivo evaluation of [125/123I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([125/123I]-OI5V) as a potential sigma-1 receptor ligand for SPECT.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (－)‐o‐[11C]methyl‐trans‐decalinvesamicol ((－)‐[11C]OMDV) as a PET ligand for the vesicular acetylcholine transporter2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a novel radiobromine-labeled sigma-1 receptor imaging probe2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo differences between two optical isomers of radioiodinated o-iodo-trans-decalinvesamicol for use as a radioligand for the vesicular acetylcholine transporter.2016

Author(s)

Kozaka Takashi 小阪孝史

KOZAKA Takashi 小阪孝史