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Sawai Hitomi  澤井 仁美

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SAWAI Hitomi  澤井 仁美

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Researcher Number 50584851
Other IDs
Affiliation (Current) 2025: 大阪公立大学, 大学院理学研究科, 教授
2025: 分子科学研究所, 特別研究部門, 教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 長崎大学, 工学研究科, 准教授
2021: 兵庫県立大学, 理学研究科, 助教
2013 – 2020: 兵庫県立大学, 生命理学研究科, 助教
2011: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 特任助教
2010: 大学共同利用機関法人自然科学研究機構(共通施設), 岡崎統合バイオサイエンスセンター, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 37010:Bio-related chemistry / Inorganic chemistry / Structural biochemistry
Except Principal Investigator
Complex systems / Basic Section 43020:Structural biochemistry-related / Bio-related chemistry
Keywords
Principal Investigator
鉄代謝 / 構造機能解析 / ヘム / 腸管モデル細胞 / 鉄イオン輸送 / 鉄シャペロン / 鉄イオンの細胞内動態 / 鉄トランスポーター / 鉄貯蔵タンパク質 / 細胞内の鉄輸送 … More / 鉄栄養素の吸収 / 細胞内鉄動態 / 鉄輸送タンパク質 / 鉄吸収 / 膜タンパク質 / Caco-2-kh細胞 / 構造機能相関 / X線結晶構造解析 / ヘム酵素 / 金属トランスポーター / ヒト腸管モデル細胞 / 鉄イオンの吸収 / 鉄還元酵素 / シャペロン / 生体分子 / 蛋白質 / 鉄栄養 / 輸送タンパク質 / PASドメイン / 酸素センサー / X線結晶構造解析 / 共鳴ラマン分光法 / ヘム含有PASドメイン / 走化性制御 / シグナル伝達タンパク質 / センサータンパク質 / ヘムタンパク質 … More
Except Principal Investigator
鉄センサー / 構造解析 / 鉄含有酵素 / センサータンパク質 / 鉄トランスポーター / 構造ダイナミクス / タンパク質複合体 / ヘム鉄 / 構造機能解析 / フェリチン / 鉄含有タンパク質 / 鉄センサータンパク質 / 鉄還元酵素 / トランスポーター / 鉄動態 / 生体鉄 / X線 / ヘム / ビタミンC / X線結晶構造解析 / 電子伝達 / ヘムタンパク質 / 環境科学 / 窒素循環 / 分子進化 / 温室効果ガス / 酵素反応 / 膜タンパク質 / 金属酵素 / 呼吸酵素 / 一酸化窒素還元酵素 / 脱窒 / 一酸化窒素 Less
  • Research Projects

    (7 results)
  • Research Products

    (139 results)
  • Co-Researchers

    (12 People)
  •  Elucidation of the intracellular molecular mechanisms of iron trafficking in intestinal epithelial cellsPrincipal Investigator

    • Principal Investigator
      Sawai Hitomi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      Nagasaki University
      University of Hyogo
  •  Strctural and Functional Dynamics on Proteins Related to Biometal Dynamics

    • Principal Investigator
      SHIRO Yoshitsugu
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Hyogo
  •  Structure-guided functional analysis of membrane proteins for human iron absorption using living cellsPrincipal Investigator

    • Principal Investigator
      Sawai Hitomi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      University of Hyogo
  •  Strucutral analysis of the membrane proteins involved in metal transport

    • Principal Investigator
      Sugimoto Hiroshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Molecular Science of NO Dyanmics in Biological System

    • Principal Investigator
      Shiro Yoshitsugu
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Bio-related chemistry
    • Research Institution
      University of Hyogo
      Institute of Physical and Chemical Research
  •  Molecular mechanisms of intercellular heme transport by a heme chaperon HRG-3Principal Investigator

    • Principal Investigator
      Sawai Hitomi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Inorganic chemistry
    • Research Institution
      University of Hyogo
  •  Structure and function of a novel signal transducer protein that employs heme-PAS domain as a sensorPrincipal Investigator

    • Principal Investigator
      SAWAI Hitomi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Structural biochemistry
    • Research Institution
      大学共同利用機関法人自然科学研究機構(岡崎共通研究施設)
      National Institutes of Natural Sciences Okazaki Research Facilities

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] 生命金属ダイナミクス2021

    • Author(s)
      城宜嗣、澤井仁美、當舎武彦
    • Total Pages
      511
    • Publisher
      エヌ・ティー・エス出版
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Book] NTS出版2021

    • Author(s)
      城宜嗣、澤井仁美、當舍武彦
    • Total Pages
      13
    • Publisher
      生命金属のダイナミクス
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Book] Chapter 3: Haem-based Sensors of Dioxygen in Gas Sensing in Cells (Editor: Shigetoshi Aono)2018

    • Author(s)
      Hitomi Sawai, Yoshitsugu Shiro
    • Total Pages
      37
    • Publisher
      Royal Society of Chemistry
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Book] Gas Sensing in Cells2017

    • Author(s)
      H. Sawai, Y. Shiro
    • Total Pages
      302
    • Publisher
      The Royal Society of Chemistry Metals in Biology
    • ISBN
      9781782628958
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Carbohydrate-binding ability of a recombinant protein containing the DM9 motif from <i>Drosophila melanogaster</i>2024

    • Author(s)
      Hatakeyama Tomomitsu、Kojima Fuki、Ohkawachi Issei、Sawai Hitomi、Unno Hideaki
    • Journal Title

      The Journal of Biochemistry

      Volume: ‐ Issue: 6 Pages: 659-669

    • DOI

      10.1093/jb/mvae014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Journal Article] Survival of Pathogenic Bacteria: The Molecular Mechanism of the Heme-responsive Sensor Protein PefR2023

    • Author(s)
      SAWAI Hitomi
    • Journal Title

      Seibutsu Butsuri

      Volume: 63 Issue: 2 Pages: 102-103

    • DOI

      10.2142/biophys.63.102

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Journal Article] Structural Basis of Heme-responsive Sensor Protein Mediating the Survival of Hemolytic Bacteria.2022

    • Author(s)
      H. Sawai, Y. Shiro
    • Journal Title

      SPring-8/SACLA Research Frontiers 2021

      Volume: 2021 Pages: 26-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Journal Article] Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion.2022

    • Author(s)
      Hieu VN, Thuy LTT, Hai H, Dat NQ, Hoang DV, Hanh NV, Phuong DM, Hoang TH, Sawai H, Shiro Y, Sato-Matsubara M, Oikawa D, Tokunaga F, Yoshizato K, Kawada N.
    • Journal Title

      Redox Biol.

      Volume: 52 Pages: 102286-102286

    • DOI

      10.1016/j.redox.2022.102286

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02688, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-23K24322
  • [Journal Article] Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival2021

    • Author(s)
      Nishinaga Megumi、Sugimoto Hiroshi、Nishitani Yudai、Nagai Seina、Nagatoishi Satoru、Muraki Norifumi、Tosha Takehiko、Tsumoto Kouhei、Aono Shigetoshi、Shiro Yoshitsugu、Sawai Hitomi
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 467-467

    • DOI

      10.1038/s42003-021-01987-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05762, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03093, KAKENHI-PROJECT-18K05321, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-21H02421, KAKENHI-PROJECT-20K06517, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
  • [Journal Article] XFEL Crystal Structures of Peroxidase Compound II2021

    • Author(s)
      Kwon, H., Basran, J., Pathak, C., Hussain, M., Freeman, S. L., Fielding, A. J., Bailey, A. J., Stefanou, N., Sparkes, H. A., Tosha, T., Yamashita, K., Hirata, K., Murakami, H., Ueno, G., Ago, H., Tono, K., Yamamoto, M., Sawai, H., Shiro, Y., Sugimoto, H., Raven, E., Moody, P. C. E.
    • Journal Title

      Angewandte Chemie International Edition

      Volume: - Issue: 26 Pages: 14578-14585

    • DOI

      10.1002/anie.202103010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05452, KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-21K05281
  • [Journal Article] NO Dynamics in Microbial Denitrification System2021

    • Author(s)
      Tosha Takehiko、Yamagiwa Raika、Sawai Hitomi、Shiro Yoshitsugu
    • Journal Title

      Chemistry Letters

      Volume: 50 Issue: 2 Pages: 280-288

    • DOI

      10.1246/cl.200629

    • NAID

      130007986360

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05761, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-19K22208
  • [Journal Article] Integrated bio-metal science: New frontiers of bio-metal science opened with cutting-edge techniques2020

    • Author(s)
      Sawai Hitomi、Ishimori Koichiro
    • Journal Title

      Biophysics and Physicobiology

      Volume: 17 Issue: 0 Pages: 94-97

    • DOI

      10.2142/biophysico.BSJ-2020017

    • NAID

      130007919808

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Journal Article] Missing Piece of Two-Component Signal Transduction Systems Unveiled by SEC-SAXS.2019

    • Author(s)
      Hitomi Sawai, Yoshitsugu Shiro
    • Journal Title

      SPring-8/SACLA Research Frontiers 2018

      Volume: 1 Pages: 15-16

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Journal Article] Missing Piece of Two-Component Signal Transduction Systems Unveiled by SEC-SAXS2019

    • Author(s)
      H. Sawai, Y. Shiro
    • Journal Title

      SPring-8/SACLA Research Frontiers 2018

      Volume: - Pages: 15-16

    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Journal Article] Roles of N- and C-terminal domains in the ligand-binding properties of cytoglobin2018

    • Author(s)
      Hanai Shumpei、Tsujino Hirofumi、Yamashita Taku、Torii Ryo、Sawai Hitomi、Shiro Yoshitsugu、Oohora Koji、Hayashi Takashi、Uno Tadayuki
    • Journal Title

      Journal of Inorganic Biochemistry

      Volume: 179 Pages: 1-9

    • DOI

      10.1016/j.jinorgbio.2017.11.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Journal Article] Roles of N- and C-terminal domains in the ligand-binding properties of cytoglobin2018

    • Author(s)
      S. Hanai, H.i Tsujino, T. Yamashita, R. Torii, H. Sawai, Y. Shiro, K. Oohora, T. Hayashi, T. Uno
    • Journal Title

      J. Inorg. Biochem.

      Volume: 179 Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate.2018

    • Author(s)
      Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H.
    • Journal Title

      Communications Biology

      Volume: 1 Issue: 1 Pages: 120-120

    • DOI

      10.1038/s42003-018-0121-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-18H02396
  • [Journal Article] Pseudomonas aeruginosa overexpression system of nitric oxide reductase for in vivo and in vitro mutational analyses2018

    • Author(s)
      Yamagiwa Raika、Kurahashi Takuya、Takeda Mariko、Adachi Mayuho、Nakamura Hiro、Arai Hiroyuki、Shiro Yoshitsugu、Sawai Hitomi、Tosha Takehiko
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Bioenergetics

      Volume: 1859 Issue: 5 Pages: 333-341

    • DOI

      10.1016/j.bbabio.2018.02.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15K07351, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-26220807
  • [Journal Article] Architecture of a Complete Two-Component Signal Transduction System: Oxygen-Sensing Proteins FixL, FixJ, and Their Complex2018

    • Author(s)
      G. S. A. Wright, A. Saeki, T. Hikima, Y. Nishizono, T. Hisano, M. Yamamoto, S. V. Antonyuk, S. S. Hasnain, Y. Shiro, H. Sawai
    • Journal Title

      Sci. Signal.

      Volume: 11 Issue: 525

    • DOI

      10.1126/scisignal.aaq0825

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-18K05321
  • [Journal Article] Dynamics of Nitric Oxide Controlled by Protein Complex in Bacterial System2017

    • Author(s)
      E. Terasakaa, K. Yamada, P.-H. Wang, K. Hosokawa, R. Yamagiwa, K. Matsumoto, S. Ishii, T. Mori, K. Yagi, H. Sawai, H. Arai, H. Sugimotoa, Y. Sugitac, Y. Shiroa, T. Tosha
    • Journal Title

      Proc. Natl. Acd. SCI. USA

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Dynamics of Nitric Oxide Controlled by Protein Complex in Bacterial System2017

    • Author(s)
      Erina Terasaka, Kenta Yamada, Po-Hung Wang, Kanta Hosokawa, Raika Yamagiwa, Kimi Matsumoto, Shoko Ishii, Takaharu Mori, Kiyoshi Yagi, Hitomi Sawai, Hiroyuki Arai, Hiroshi Sugimoto, Yuji Sugita, Yoshitsugu Shiro and Takehiko Tosha
    • Journal Title

      PNAS

      Volume: 114 Issue: 37 Pages: 9888-9893

    • DOI

      10.1073/pnas.1621301114

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26119006, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-15K07351
  • [Journal Article] Heme-binding properties of HupD functioning as a substrate-binding protein in a heme-uptake ABC-transporter system in Listeria monocytogenes2014

    • Author(s)
      Y. Okamoto, H. Sawai, M. Ogura, T. Uchida, K. Ishimori, T. Hayashi, S. Aono
    • Journal Title

      Bull. Chem. Soc. Jpn.

      Volume: 87 Issue: 10 Pages: 1140-1146

    • DOI

      10.1246/bcsj.20140166

    • NAID

      130004677557

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25550047, KAKENHI-PROJECT-25871213
  • [Journal Article] Disulfide Bonds Regulate Binding of Exogenous Ligand to Human Cytoglobin2014

    • Author(s)
      H. Tsujino, T. Yamashita, A. Nose, K. Kukino, H. Sawai, Y. Shiro, T. Uno
    • Journal Title

      J. Inor. Biochem.

      Volume: 135 Pages: 20-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26220807
  • [Journal Article] Disulfide bonds regulate binding of exogenous ligand to human cytoglobin.2014

    • Author(s)
      Tsujino, H., Yamashita, T., Nose, A., Kukino, K., Sawai, H., Shiro, Y., Uno, T.
    • Journal Title

      J. Inorg. Biochem.

      Volume: 135C Pages: 20-27

    • DOI

      10.1016/j.jinorgbio.2014.02.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Journal Article] サイトグロビンの分子構造2013

    • Author(s)
      澤井仁美、城宜嗣
    • Journal Title

      月刊 「細胞」

      Volume: 45 Pages: 9-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Journal Article] Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginose2012

    • Author(s)
      Hitomi Sawai, Hiroshi Sugimoto, Yoshitsugu Shiro, Haruto Ishikawa, Yasuhisa Mizutani, Shigetoshi Aono
    • Journal Title

      Chemical Communications

      Volume: 48 Pages: 6523-6525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Journal Article] Aldoxime Dehydratase : Probing the Heme Environment Involved in the Synthesis of the Carbon-Nitrogen Triple Bond2011

    • Author(s)
      Eftychia Pinakoulaki, Constantinos Koutsoupakis, Hitomi Sawai, Andrea Pavlou, Yasuo Kato, Yasuhisa Asano, Shigetoshi Aono
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 115 Pages: 13012-13018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Journal Article] Crystal Structure of Carbonmonoxide Complex of Human Cytoglobin2011

    • Author(s)
      M.Makino, H.Sawai, Y.Shiro, H.Sugimoto
    • Journal Title

      PROTEINS

      Volume: 79 Issue: 4 Pages: 1143-1153

    • DOI

      10.1002/prot.22950

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22105012, KAKENHI-PROJECT-22870043
  • [Presentation] 鉄を摂取して健康になるための分子科学2024

    • Author(s)
      澤井仁美
    • Organizer
      日本農芸化学会2024年度大会創立100周年記念大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 植物とヒトの鉄獲得機構の分子レベルでの相違点2024

    • Author(s)
      澤井仁美
    • Organizer
      第65回日本植物生理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒトの鉄栄養素の吸収と輸送に関わるタンパク質間の分子機序2024

    • Author(s)
      澤井仁美
    • Organizer
      生物無機化学シンポジウム2024
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Molecular Mechanism of Iron Trafficking into Ferritin via Iron Chaperone2023

    • Author(s)
      Atsuto Ura, Izumi Yanatori, Takehiko Tosha, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      20th International Conference on Biological Inorganic Chemistry (ICBIC20)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Thinking about Iron: the Molecular and Cellular Mechanisms of Dietary Iron Absorption2023

    • Author(s)
      Hitomi Sawai
    • Organizer
      20th International Conference on Biological Inorganic Chemistry (ICBIC20)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Molecular Mechanisms of the Iron Binding and Transport by PCBP2023

    • Author(s)
      Atsuto Ura, Izumi Yanatori, Takehiko Tosha, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      日本生物物理学会第14回中国四国支部大会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] PCBP-Ferritin相互作用解析に基づく細胞内鉄代謝機構の解明2023

    • Author(s)
      浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      令和5年度バイオダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 鉄還元機能を持つ6回膜貫通型タンパク質101F6の大腸菌での発現と機能解析2023

    • Author(s)
      阪口智哉、澤井仁美、城 宜嗣、鍔木基成、當舎武彦、木村哲就、杉本宏
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 蛋白質間相互作用による鉄ホメオスタシスの制御2023

    • Author(s)
      澤井仁美
    • Organizer
      第23回日本蛋白質科学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Food for Thought: the Protein Interactions for Dietary Iron Absorption in Humans2023

    • Author(s)
      Hitomi Sawai
    • Organizer
      UK-Japan Meeting and Workshop: Dynamic Crystallography-XFELs and Synchrotrons to study enzyme reactions
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒトの膜貫通型鉄還元酵素DcytbのC末端領域の役割2023

    • Author(s)
      入江帆美、浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      第35回生物無機化学夏季セミナー
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Thinking about Iron: the Molecular and Cellular Mechanisms of Dietary Iron Absorption2023

    • Author(s)
      Hitomi Sawai
    • Organizer
      20th International Conference on Biological Inorganic Chemistry (ICBIC20)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 膜貫通型鉄還元酵素Dcytbと細胞内鉄輸送タンパク質PCBPの相互作用の検討2023

    • Author(s)
      宮脇まどか、浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      第35回生物無機化学夏季セミナー
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 細胞内での鉄の輸送と貯蔵の分子メカニズム2023

    • Author(s)
      浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      第35回生物無機化学夏季セミナー
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 鉄シャペロンタンパク質PCBPによる鉄イオン輸送機構の解明2023

    • Author(s)
      浦 敦人、簗取 いずみ、城 宜嗣、澤井 仁美
    • Organizer
      第23回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒト由来鉄還元酵素Dcytbと二価金属輸送体DMT1の相互作用解析に向けた恒常共発現系の構築2023

    • Author(s)
      坂上正虎、柴田晃利、阪口智哉、藤宇将吾、髙原教代、簗取いずみ、城 宜嗣、當舎武彦、澤井仁美
    • Organizer
      第35回生物無機化学夏季セミナー
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒトの鉄吸収に関わる膜貫通型鉄還元酵素Dcytbと鉄輸送タンパク質PCBPの複合体化の検討2023

    • Author(s)
      宮脇まどか、浦 敦人、簗取いずみ、城 宜嗣、澤井仁美
    • Organizer
      令和5年度日本生化学会 九州支部例会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒト由来二価金属輸送体DMT1と鉄還元酵素Dcytbの相互作用解析に向けて2023

    • Author(s)
      坂上正虎、髙原教代、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      令和5年度バイオダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Food for thought: the Protein Interactions for Dietary Iron Absorption in Humans2023

    • Author(s)
      Hitomi Sawai
    • Organizer
      UK/Japan Meeting and Workshop: Dynamic Crystallography;XFELs and Synchrotrons to study enzyme reactions
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 鉄輸送シャペロンPCBPと鉄貯蔵タンパク質Ferritinの複合体形成の分子機構2023

    • Author(s)
      佐藤 渚、浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      第35回生物無機化学夏季セミナー
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 膜貫通型鉄還元酵素Dcytbと鉄輸送タンパク質PCBPの複合体化2023

    • Author(s)
      宮脇 まどか、浦 敦人、簗取 いずみ、當舎 武彦、城 宜嗣、澤井 仁美
    • Organizer
      第2回生命金属科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 細胞内鉄輸送に関わる鉄シャペロンと鉄貯蔵タンパク質の複合体形成の分子機構2023

    • Author(s)
      佐藤 渚、浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 細胞内鉄輸送タンパク質PCBPにおけるヘム鉄の結合解析2023

    • Author(s)
      竹下はな、浦 敦人、簗取いずみ、當舎武彦、城 宜嗣、澤井仁美
    • Organizer
      第35回生物無機化学夏季セミナー
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒトの鉄栄養吸収に関わる膜タンパク質の構造機能解析2023

    • Author(s)
      澤井仁美
    • Organizer
      第13回トランスポーター研究会九州部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 金属蛋白質のための放射光構造生物学2023

    • Author(s)
      澤井仁美
    • Organizer
      九州シンクロトロン光応用研究センター講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Metal Dynamics via Proteins: Understanding of the Uptake, Trafficking and Regulation of Biometals by the Relay of Protein-Protein Interactions2023

    • Author(s)
      Hitomi Sawai
    • Organizer
      LINXS ChemLife WG3 Kick-off Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Heme Controls the Structural Rearrangement of Its Sensor Protein Mediating Survival of Pathogenic Bacteria.2022

    • Author(s)
      Hitomi Sawai
    • Organizer
      10th Asian Biological Inorganic Chemistry Conference (AsBIC10)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 腸管における鉄栄養の吸収輸送という現象を多様な分子の相互作用として捉えて精密に理解する研究2022

    • Author(s)
      澤井仁美
    • Organizer
      第1回生命金属科学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 鉄栄養素の細胞内動態を分子と細胞の階層で探る2022

    • Author(s)
      澤井仁美
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] センサータンパク質による鉄毒性の回避メカニズム2022

    • Author(s)
      澤井仁美
    • Organizer
      メタルバイオサイエンス研究会2022
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 生体内の鉄の動態と機能2022

    • Author(s)
      澤井仁美
    • Organizer
      第34回生物無機化学夏季セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 細胞内鉄輸送タンパク質PCBP1における鉄イオンの結合と輸送の分子メカニズム2022

    • Author(s)
      浦 敦人、簗取いずみ、城 宜嗣、澤井仁美
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 鉄の生体内動態:栄養素あるいは細胞毒としての鉄を制御する仕組み2022

    • Author(s)
      澤井仁美
    • Organizer
      日本農芸化学会2022年度西日本支部大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Heme Controls the Structural Rearrangement of Its Sensor Protein Mediating Survival of Pathogenic Bacteria2022

    • Author(s)
      H. Sawai
    • Organizer
      10th Asian Biological Inorganic Chemistry Conference (AsBIC10)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] ヒトの細胞内における鉄イオンの輸送と貯蔵の分子メカニズム2022

    • Author(s)
      浦 敦人、簗取いずみ、城 宜嗣、澤井仁美
    • Organizer
      日本農芸化学会2022年度西日本支部大会
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Heme Controls the Structural Rearrangement of Its Sensor Protein Mediating the Survival of Hemolytic Bacteria.2022

    • Author(s)
      Hitomi Sawai
    • Organizer
      Gordon Research Conference: Chemistry and Biology of Tetrapyrroles
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] 膜タンパク質の立体構造を基盤とする腸管モデル細胞を用いた鉄イオン吸収メカニズムの解析2021

    • Author(s)
      澤井 仁美
    • Organizer
      生理学研究所研究会「上皮膜輸送の多様性・調和機構を基盤とする異分野融合研究の創出」
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒトにおける鉄イオンの吸収に関わる膜タンパク質の構造機能相関と腸管細胞モデルでの機能評価系を用いた鉄イオン吸収を向上させる新たな化合物スクリーニング2021

    • Author(s)
      澤井仁美
    • Organizer
      日本薬学会第141年会 環境・衛生部会若手研究者シンポジウム~金属研究の新たな切り口:分子からヒトを対象とした研究最前線~
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 鉄イオンの吸収に関わる膜タンパク質の構造と腸管モデル細胞を用いた機能解析2021

    • Author(s)
      澤井仁美
    • Organizer
      第1回トランスポーター研究会関西部会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] ヒトにおける鉄イオンの吸収に関わる膜タンパク質の構造機能相関と腸管細胞モデルでの機能評価系を用いた鉄イオン吸収を向上させる新たな化合物スクリーニング2021

    • Author(s)
      澤井 仁美
    • Organizer
      日本薬学会第141年会 環境・衛生部会若手研究者シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] 鉄イオンの吸収に関わる膜タンパク質の構造と腸管モデル細胞を用いた機能解析2021

    • Author(s)
      澤井 仁美
    • Organizer
      第1回トランスポーター研究会関西部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] ヒト腸管細胞モデル系を用いた鉄イオンの吸収を向上させる食品成分の探索とそれらの成分が鉄輸送関連タンパク質に作用する分子機構2021

    • Author(s)
      髙原教代、杉本宏、神戸大朋、城宜嗣、澤井仁美
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Structural insights into the multifunctionality of the heme-responsive sensor protein for detoxification in hemolytic bacteria2021

    • Author(s)
      Hitomi Sawai
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2021 (Pacifichem2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Structural Insights into the Multifunctionality of the Heme-responsive Sensor Protein for Detoxification in Hemolytic Bacteria2021

    • Author(s)
      H. Sawai
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2021 (Pacifichem 2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] Structural basis for the multifunctionality of the heme-responsive sensor protein for heme detoxification in hemolytic bacteria.2021

    • Author(s)
      Hitomi Sawai
    • Organizer
      11th International Conference on Porphyrins and Phthalocyanines (ICPP-11)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05281
  • [Presentation] Structural Basis for the Multifunctionality of the Heme-responsive Sensor Protein for Heme Detoxification in Hemolytic Bacteria2021

    • Author(s)
      H. Sawai
    • Organizer
      11th International Conference on Porphyrins and Phthalocyanines (ICPP-11)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 溶血性連鎖球菌が宿主の血中から鉄を獲得するシステムで機能するセンサータンパク質の多機能性に関する分子機序2020

    • Author(s)
      澤井仁美
    • Organizer
      日本薬学会第140年会 環境・衛生部会若手研究者シンポジウム「生体分子およびタンパク質との相互作用から見た生命金属動態」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] ヒトの鉄イオン吸収に関わる膜タンパク質の立体構造に基づく培養細胞を用いた機能解析2020

    • Author(s)
      澤井仁美
    • Organizer
      日本薬学会第140年会 環境・衛生部会シンポジウム~生体分子およびタンパク質との相互作用から見た生命金属動態~
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] ヒト腸管モデル細胞を用いた鉄イオンの吸収の吸収に関わる膜タンパク質の構造機能相関解析2020

    • Author(s)
      澤井仁美
    • Organizer
      新学術領域研究「生命金属科学」第4回領域会議
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 病原菌の栄養源としての鉄を感知するタンパク質の分子機構解析2019

    • Author(s)
      澤井仁美
    • Organizer
      第1回全学研究会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural basis of ascorbate-dependent iron reduction by human Dcytb involved in intestinal iron absorption2019

    • Author(s)
      Hiroshi Sugimoto, Menega Ganasen, Hiromi Togashi, Hanae Takeda, Yoshitsugu Shiro, A Grant Mauk, Hitomi Sawai
    • Organizer
      32nd European Crystallographic Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] 病原菌の鉄獲得システムで機能するヘムセンサー蛋白質の多機能性とその構造的機序2019

    • Author(s)
      澤井仁美
    • Organizer
      第19回日本蛋白質科学会年会/第71回日本細胞生物学会大会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 「鉄」のバイオサイエンス2019

    • Author(s)
      澤井仁美
    • Organizer
      第29回STクラブ
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 酸素センサータンパク質FixLのセンサーモジュールの構造解析2019

    • Author(s)
      鎌屋美咲、小手石泰康、當舎武彦、馬場清喜、杉本宏、城宜嗣、澤井仁美
    • Organizer
      第19回日本蛋白質科学会年会/第71回日本細胞生物学会大会合同年次大会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 原子から細胞レベルの研究による鉄イオンの吸収メカニズムの理解と有効な鉄栄養強化食品成分の探索2019

    • Author(s)
      澤井仁美
    • Organizer
      第92回日本生化学会大会シンポジウム「生体内におけるSingularity Elementsとしての生体金属の利用と制御」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 病原菌の鉄獲得システムで機能するヘムセンサータンパク質の構造機能相関の解明2019

    • Author(s)
      澤井仁美
    • Organizer
      第43回日本鉄バイオサイエンス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 鉄吸収の分子論: 食物に含まれる鉄イオンの獲得機構を詳細に理解すること2019

    • Author(s)
      澤井仁美
    • Organizer
      第1回全学研究会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural Basis for Enhancement of Human Iron Absorption by Duodenal Membrane Proteins with Some Dietary Metal-Chelators.2019

    • Author(s)
      Hitomi Sawai
    • Organizer
      7th International Symposium on Metallomics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 病原菌の鉄獲得システムで機能するヘムセンサー蛋白質の多機能性とその構造的機序2019

    • Author(s)
      西永惠、長井聖奈、村木則文、青野重利、杉本宏、城宜嗣、澤井仁美
    • Organizer
      第19回日本蛋白質科学会年会/第71回日本細胞生物学会大会合同年次大会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 膜タンパク質の立体構造解析における脂質の効果2019

    • Author(s)
      澤井仁美
    • Organizer
      第5回Integrated Lipidology領域会議
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 原子から細胞レベルの研究による鉄イオンの吸収メカニズムの理解と有効な鉄栄養強化食品成分の探索2019

    • Author(s)
      澤井仁美
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05761
  • [Presentation] 環境変化に応じて生命を維持するための精密機械「センサータンパク質」の仕組みを探る2019

    • Author(s)
      澤井仁美
    • Organizer
      「物質階層原理研究」&「ヘテロ界面研究」合同集会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural Basis for the Transcriptional Regulation of Heme Detoxification Involved in Pathogenic Bacterial Iron Acquisition.2019

    • Author(s)
      Megumi Nishinaga, Seina Nagai, Norifumi Muraki, Satoru Nagatoishi, Kouhei Tsumoto, Shigetoshi Aono, Hiroshi Sugimoto, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      7th International Symposium on Metallomics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 病原菌の鉄獲得システムで機能するヘムセンサー蛋白質の多機能性とその構造的機序2019

    • Author(s)
      澤井仁美
    • Organizer
      第19回日本蛋白質科学会年会/第71回日本細胞生物学会大会合同年次大会ワークショップ「生命金属とタンパク質による細胞機能の協奏的制御」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural Basis for Enhancement of Human Iron Absorption by Duodenal Membrane Proteins with ascorbate and dietary metal chelators.2019

    • Author(s)
      Hitomi Sawai
    • Organizer
      Seminar of School of Chemistry & School of Biochemistry, University of Bristol
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural Basis for the Intramolecular Signal Transduction of Oxygen Sensor Protein FixL from Bradyrhizobium japonicum.2019

    • Author(s)
      鎌屋美咲、小手石泰康、當舎武彦、馬場清喜、杉本宏、城宜嗣、澤井仁美
    • Organizer
      日本生物物理学会第57回年会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] 生体内金属動態の統合的研究2019

    • Author(s)
      澤井仁美
    • Organizer
      兵庫県立大学太田学長と女性研究者の集い
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural basis of iron reduction by human duodenal cytochrome b (Dcytb) involved in intestinal iron absorption2019

    • Author(s)
      Hiroshi Sugimoto, Menega Ganasen, Hiromi Togashi, Hanae Takeda, Yoshitsugu Shiro, A Grant Mauk, Hitomi Sawai
    • Organizer
      19th International Conference on Biological Inorganic Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] SEC-SAXS法を用いることで解明できた酸素センサータンパク質システムFixL/FixJの全体像とシグナル伝達機構2018

    • Author(s)
      澤井仁美
    • Organizer
      大阪大学蛋白質研究所セミナー/SPring-8先端利用技術ワークショップ「第2回SPring-8における蛋白質構造生物学研究の現状と将来」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural basis for enhancement of human iron uptake by duodenal ferric reductase with ascorbate2018

    • Author(s)
      Hitomi Sawai
    • Organizer
      9th Asian Biological Inorganic Chemistry (AsBIC-9)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] ヒトの鉄イオン吸収に関わる膜タンパク質の立体構造に基づく生きた細胞での機能解析2018

    • Author(s)
      Menega Ganasen, 藤代瞳、Xiaojing Yuan, Iqbal Hamza, 姫野誠一郎、A. Grant Mauk, 杉本宏、城宜嗣、澤井仁美
    • Organizer
      メタルバイオサイエンス研究会2018
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] ヒトの鉄吸収に関わる膜貫通型鉄還元酵素の立体構造に基づく生きた細胞での機能解析2018

    • Author(s)
      澤井仁美
    • Organizer
      第18回日本蛋白質科学会年会ワークショップ「金属イオンとタンパク質:その密接な関係が破綻するとき」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Understanding the Mechanism of Dietary Iron Absorption at the Atomic level2018

    • Author(s)
      M. Ganasen, H. Asakura, T. Tosha, T. Urano, X. Yuan, I. Hamza, A. G. Mauk, Y. Shiro, H. Sugimoto, H. Sawai
    • Organizer
      第91回日本生化学会年会
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] ヒト小腸の細胞膜でDcytbが鉄分吸収を促進するメカニズム2018

    • Author(s)
      Menega Ganasen、冨樫ひろ美、山下恵太郎、平田邦生、Grant A. Mauk、城 宜嗣、澤井仁美、杉本 宏
    • Organizer
      平成30年度結晶学会年会
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] ヒトの鉄イオン吸収に関わる膜タンパク質の立体構造を基盤とした機能と構造の相互解析2018

    • Author(s)
      澤井仁美
    • Organizer
      第42回日本鉄バイオサイエンス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural Basis for Promotion of Human Iron Absorption by Duodenal Ferric Reductase with Ascorbate and Some Dietary Metal-chelators2018

    • Author(s)
      H. Sawai
    • Organizer
      Cold Spring Harbor Asia Meeting: Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] ヒトの鉄イオン吸収に関わる膜タンパク質の立体構造を基盤とした機能と構造の相互解析2018

    • Author(s)
      澤井仁美
    • Organizer
      第42回日本鉄バイオサイエンス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] Structure-guided functional analysis of human ferric reductase using living cells2018

    • Author(s)
      Hitomi Sawai
    • Organizer
      Gordon Research Conference: 2018 Chemistry and Biology of Tetrapyrroles
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structural basis of ascorbate-dependent iron reduction by human duodenal cytochrome b (Dcytb) involved in intestinal iron absorption2018

    • Author(s)
      H. Sugimoto, M. Ganesen, H. Togashi, H. Takeda, H. Asakura, T. Tosha, K. Yamashita, K. Hirata, X. Yuan, I. Hamza, A. G. Mauk, Y. Shiro, H. Sawai
    • Organizer
      Asian Crystallographic Association Conference (AsCA 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] Structural Basis for Enhancement of Human Iron Uptake by Duodenal Ferric Reductase with Ascorbate2018

    • Author(s)
      H. Sawai
    • Organizer
      9th Asian Biological Inorganic Chemistry (AsBIC-9)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] 小腸上皮細胞膜で機能する鉄還元酵素Dcytbの結晶構造2018

    • Author(s)
      杉本宏, Menega Ganasen 冨樫ひろ美,武田英恵, 朝倉帆南, 山下恵太郎,平田邦生, A. Grant Mauk,城宜嗣,澤井仁美
    • Organizer
      平成30年度 内外環境応答・代謝酵素研究会
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] ヒトの鉄吸収機構を原子・分子⇔細胞・組織の階層で相互に理解する2018

    • Author(s)
      澤井仁美
    • Organizer
      「物質階層原理」&「ヘテロ界面研究」合同集会
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Structure-guided Functional Analysis of Human Ferric Reductase Using Living Cells2018

    • Author(s)
      Menega Ganasen, Hitomi Fujishiro, Xiaojing Yuan, Iqbal Hamza, A. Grant Mauk, Seiichiro Himeno, Hiroshi Sugimoto, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      Gordon Research Conference: 2018 Chemistry and Biology of Tetrapyrroles
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] Structural Insight into the Dietary Non-heme Iron Absorption in Human Duodenum2018

    • Author(s)
      M. Ganasen, H. Asakura, T. Tosha, X. Yuan, I. Hamza, A. G. Mauk, Y. Shiro, H. Sugimoto and H. Sawai
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] Structural basis for promotion of human iron absorption by duodenal ferric reductase with ascorbate and some dietary metal-chelators2018

    • Author(s)
      Hitomi Sawai
    • Organizer
      Cold Spring Harbor Asia Meeting: Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] ヒトの鉄イオン吸収に関わる膜タンパク質の立体構造に基づく生きた細胞での機能解析2018

    • Author(s)
      M. Ganasen, 藤代瞳、X. Yuan, I. Hamza, 姫野誠一郎、A. G. Mauk, 杉本宏、城宜嗣、澤井仁美
    • Organizer
      メタルバイオサイエンス研究会2018
    • Data Source
      KAKENHI-PROJECT-18H02396
  • [Presentation] ヒトの鉄吸収機構を「膜タンパク質」と「生きた細胞」の研究により相互に理解する2018

    • Author(s)
      澤井仁美
    • Organizer
      第91回日本生化学会年会ワークショップ「生体金属のMagical Powerとその研究最前線」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K05321
  • [Presentation] Characterization of CeHRG-4 as a novel heme transporter in animals2016

    • Author(s)
      Menega Ganasen, Iqbal Hamza, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      2015 Leading program evaluation conference
    • Place of Presentation
      Center for Advanced Science and Technology (兵庫県赤穂郡)
    • Year and Date
      2016-03-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Characterization of a novel heme transporter in animals2015

    • Author(s)
      Menega Ganasen, Hitomi Sawai, Iqbal Hamza, Yoshitsugu Shiro
    • Organizer
      Science and Business &#8211; 2nd Joint Symposium of UPM and UH
    • Place of Presentation
      Center for Advanced Science and Technology (兵庫県赤穂郡)
    • Year and Date
      2015-10-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Characterization of HRG protein as a novel heme transporter in animals2015

    • Author(s)
      Menega Ganasen, Iqbal Hamza, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      3rd International Picobiology Institute Symposium
    • Place of Presentation
      Center for Advanced Science and Technology (兵庫県赤穂郡)
    • Year and Date
      2015-12-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] センサータンパク質における構造機能変換: 小さな環境変化を感知して、大きな構造変化を引き起こし、生体機能を制御いる仕組み2015

    • Author(s)
      澤井 仁美
    • Organizer
      第5回博士課程教育リーディングプログラム会議
    • Place of Presentation
      西はりま地場産業センター (兵庫県姫路市)
    • Year and Date
      2015-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Characterization of a novel heme transporter in animals2015

    • Author(s)
      Menega Ganasen, Iqbal Hamza, Yoshitsugu Shiro, Hitomi Sawai
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド (兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] 気体分子センサータンパク質における機能制御メカニズムの革新的理解のために2015

    • Author(s)
      澤井 仁美
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド (兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Molecular Mechanisms of the Transcriptional Regulation by Heme Sensing.2013

    • Author(s)
      Sawai, H., Sugimoto, H., Shiro, Y., Aono, S.
    • Organizer
      16th International Conference on Biological Inorganic Chemistry (ICBIC-16)
    • Place of Presentation
      Grenoble (France)
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Structural characterization of Aer2 that employs a heme as an oxygen sensor for aerotaxis control2012

    • Author(s)
      Hitomi Sawai, Hiroshi Sugimoto, Haruto Ishikawa, Yasuhisa Mizutani, Yoshitsugu Shiro, Shigetoshi Aono
    • Organizer
      4^<th> Japan-Korea Seminars on Biomolecular Sciences : Experiments and Simulations
    • Place of Presentation
      東大寺総合文化センター(奈良県)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] 新規な転写調節因子HesRのヘムによる機能制御の分子機構2012

    • Author(s)
      澤井仁美、杉本宏、山中優、城宜嗣、青野重利
    • Organizer
      第92回日本化学会春季年会
    • Place of Presentation
      慶応大学(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] Structural characterization of Aer2 that employs a heme as an oxygen sensor for aerotaxis control2012

    • Author(s)
      Hitomi Sawai, Hiroshi Sugimoto, Haruto Ishikawa, Yasuhisa Mizutani, Yoshitsugu Shiro, Shigetoshi Aono
    • Organizer
      4^<th> Japan-Korea Seminars on Biomolecular Sciences : Experiments and Simulations
    • Place of Presentation
      Todaiji Cultural Center(Japan)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] ヘムにより機能制御される新規な転写調節因子HesRのX線結晶構造2011

    • Author(s)
      澤井仁美、杉本宏、山中優、城宜嗣、青野重利
    • Organizer
      平成23年度日本結晶学会年会
    • Place of Presentation
      北海道大学(北海道)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] Structural characterization of Aer2 that adopts a heme-containing PAS domain as an oxygen sensor for aerotaxis control2011

    • Author(s)
      Hitomi Sawai, Hiroshi Sugimoto, Haruto Ishikawa, Yoshitsugu Shiro, Yasuhisa Mizutani, Shigetoshi Aono
    • Organizer
      15^<th> International Conference on Biological Inorganic Chemistry(ICBIC15)
    • Place of Presentation
      University of British Colombia(Canada)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] Structural characterization of Aer2 that adopts a heme-containing PAS domain as an oxygen sensor for aerotaxis control2011

    • Author(s)
      Hitomi Sawai, Hiroshi Sugimoto, Haruto Ishikawa, Yoshitsugu Shiro, Yasuhisa Mizutani, Shigetoshi Aono
    • Organizer
      15^<th> International Conference on Biological Inorganic Chemistry (ICBIC15)
    • Place of Presentation
      University of British Colombia, Vancouver (Canada)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] 新規なヘム含有O_2センサー蛋白質Aer2における気体分子の識別感知機構2011

    • Author(s)
      澤井仁美
    • Organizer
      岡崎統合バイオサイエンスセンター10周年記念シンポジウム
    • Place of Presentation
      岡崎統合バイオサイエンスセンター(愛知県)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] ヘム分子により機能制御される新規な転写調節因子HesRのX線結晶構造2011

    • Author(s)
      澤井仁美、山中優、杉本宏、城宜嗣、青野重利
    • Organizer
      第5回バイオ関連化学合同シンポジウム
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] ヘム含有PASドメインを有する新規な走化性制御蛋白質Aer2の酸素感知機構2010

    • Author(s)
      澤井仁美、石川春人、水谷泰久、青野重利
    • Organizer
      第4回バイオ関連化学合同シンポジウム
    • Place of Presentation
      大阪大学(大阪府)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] ガス分子により駆動される新規なセンサータンパク質の機能発現機構2010

    • Author(s)
      澤井仁美
    • Organizer
      平成22年度特定領域研究「細胞感覚」夏の班会議
    • Place of Presentation
      札幌市教育文化会館(北海道)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] ヘム含有PASドメインを有する新規な走化性制御蛋白質Aer2の酸素感知機構2010

    • Author(s)
      澤井仁美
    • Organizer
      第4回バイオ関連化学シンポジウム
    • Place of Presentation
      大阪大学(大阪府)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] ガス分子により駆動される新規なセンサータンパク質の機能発現機構2010

    • Author(s)
      澤井仁美、青野重利
    • Organizer
      平成22年度特定領域「細胞感覚」夏の班会議
    • Place of Presentation
      札幌市教育文化会館(北海道)
    • Data Source
      KAKENHI-PROJECT-22870043
  • [Presentation] 真核生物におけるヘムの生体内動態の分子科学

    • Author(s)
      澤井仁美、Iqbal Hamza、城宜嗣
    • Organizer
      第6回日本生物物理学会中四国支部大会
    • Place of Presentation
      とりぎん文化会館 (鳥取県鳥取市)
    • Year and Date
      2014-05-17 – 2014-05-18
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] 膜タンパク質が織り成す生体金属科学

    • Author(s)
      澤井仁美
    • Organizer
      第1回Integrated lipidology meeting
    • Place of Presentation
      日本平ホテル (静岡県静岡市)
    • Year and Date
      2015-02-24 – 2015-02-26
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Characterization of an intercellular heme carrier protein, HRG3

    • Author(s)
      Riki Yuki, Hitomi Sawai, Iqbal Hamza, Yoshitsugu Shiro
    • Organizer
      The annual evaluation conference of the leading program
    • Place of Presentation
      Center for Advanced Science & Technology Hyogo (兵庫県赤穂郡)
    • Year and Date
      2015-03-16 – 2015-03-17
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] Preparation of a novel protein involved in heme transport in animals

    • Author(s)
      Menega Ganasen, Hitomi Sawai, Iqbal Hamza, Yoshitsugu Shiro
    • Organizer
      The annual evaluation conference of the leading program
    • Place of Presentation
      Center for Advanced Science & Technology Hyogo (兵庫県赤穂郡)
    • Year and Date
      2015-03-16 – 2015-03-17
    • Data Source
      KAKENHI-PROJECT-25871213
  • [Presentation] 真核生物におけるヘムの生体内動態の分子科学

    • Author(s)
      澤井仁美
    • Organizer
      「分子システム研究」第3回春季研究会
    • Place of Presentation
      かんぽの宿彦根 (滋賀県彦根市)
    • Year and Date
      2014-04-24 – 2014-04-25
    • Data Source
      KAKENHI-PROJECT-25871213
  • 1.  Shiro Yoshitsugu (70183051)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  Sugimoto Hiroshi (90344043)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  杉田 有治 (80311190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  TOSHA Takehiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  NAKAMURA Hiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  HISANO Tamao
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  KUBO Minoru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAGI Kiyoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  ARAI Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  青野 重利
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  及川 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  浦野 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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