NAGATA KENICHI 永田健一

… Alternative Names

Nagata Kenichi 永田健一

永田健一ナガタケンイチ

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Researcher Number	50587798
Other IDs
Affiliation (Current)	2026: 名古屋大学, 医学系研究科, 特任講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 名古屋大学, 医学系研究科, 特任講師 2020: 名古屋大学, 医学系研究科, 特任助教 2018 – 2019: 大阪大学, 医学系研究科, 寄附講座講師 2015 – 2016: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 2011: Osaka City University, 医学(系)研究科(研究院), 研究員 2010: 大阪市立大学, 大学院・医学研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / General anatomy (including histology/embryology) / General anatomy (including Histology/Embryology)
Keywords	Principal Investigator シングルセルRNA-seq / ミクログリア / 神経損傷 / ノックインマウス / 軸索分岐 / 運動神経 / 先天性関節拘縮症 / ECEL1 / DINE / 老化 … More / アルツハイマー病 / ケモカイン / Creマウス / ゲノム編集 / 神経炎症 / コンディショナルノックアウトマウス / RNA-seq / ゲノム編集技術 / ECEL1/DINE / 関節拘縮症 / 神経筋接合部 / 軸索伸展 / CRISPR/Cas9 / in situ hybridization / 転写因子 / microRNA / 再生 / 神経 Less

アルツハイマー病における老化した疾患関連ミクログリアの同定Principal Investigator
- Principal Investigator
  
  永田健一
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University
Establishment of in vivo labeling system for long-term tracking of inflammation-related microgliaPrincipal Investigator
- Principal Investigator
  
  Nagata Kenichi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University
Elucidation of the pathogenic mechanism of congenital contracture disorder with ECEL1/DINE deficiencyPrincipal Investigator
- Principal Investigator
  
  Nagata Kenichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University
  Osaka University
Morphological analyses of aberrant muscle innervation in DINE-deficient motor nervesPrincipal Investigator
- Principal Investigator
  
  Nagata Kenichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Institute of Physical and Chemical Research
神経再生関連microRNAの探索および機能解析Principal Investigator
- Principal Investigator
  
  永田健一
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka City University

All 2024 2023 2020 2019 2018 2016 Other

All Journal Article Presentation

[Journal Article] Tau Accumulation Induces Microglial State Alterations in Alzheimer’s Disease Model Mice2024
- Author(s)
  Nagata K.Hashimoto S.Joho D.Fujioka R.Matsuba Y.Sekiguchi M.Mihira N.Motooka D.Liu Y.-C.Okuzaki D.Kikuchi M.Murayama S.Saido T.C.Kiyama H.Sasaguri H
- Journal Title
  
  eNeuro
  
  Volume: 11(12) Issue: 12 Pages: 0260-24
- DOI
  10.1523/eneuro.0260-24.2024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22K07347, KAKENHI-PROJECT-23K24695, KAKENHI-PROJECT-23K27497, KAKENHI-PROJECT-23K27671
[Journal Article] eIF5 stimulates the CUG initiation of RAN translation of poly-GA dipeptide repeat protein (DPR) in C9orf72 FTLD/ALS2024
- Author(s)
  Gotoh Shiho、Mori Kohji、Fujino Yuzo、Kawabe Yuya、Yamashita Tomoko、Omi Tsubasa、Nagata Kenichi、Tagami Shinji、Nagai Yoshitaka、Ikeda Manabu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 3 Pages: 105703-105703
- DOI
  10.1016/j.jbc.2024.105703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19492, KAKENHI-PROJECT-19K17111, KAKENHI-PROJECT-22KJ2148, KAKENHI-PROJECT-21H02840, KAKENHI-PLANNED-20H05927, KAKENHI-PROJECT-22K07347, KAKENHI-PROJECT-22K07559
[Journal Article] Production of a heterozygous exon skipping model of common marmosets using gene-editing technology2024
- Author(s)
  Sato Kenya、Sasaguri Hiroki、Kumita Wakako、Sakuma Tetsushi、Morioka Tomoe、Nagata Kenichi、Inoue Takashi、Kurotaki Yoko、Mihira Naomi、Tagami Michihira、Manabe Ri-ichiroh、Ozaki Kokoro、Okazaki Yasushi、Yamamoto Takashi、Suematsu Makoto、Saido Takaomi C.、Sasaki Erika
- Journal Title
  
  Lab Animal
  
  Volume: 53 Issue: 9 Pages: 244-251
- DOI
  10.1038/s41684-024-01424-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07347, KAKENHI-PROJECT-24K02014
[Journal Article] Gene-gene functional relationships in Alzheimer's disease: CELF1 regulates KLC1 alternative splicing2024
- Author(s)
  Kikuchi Masataka、Viet Justine、Nagata Kenichi、Sato Masahiro、David Geraldine、Audic Yann、Silverman Michael A.、Yamamoto Mitsuko、Akatsu Hiroyasu、Hashizume Yoshio、Takeda Shuko、Akamine Shoshin、Miyamoto Tesshin、Uozumi Ryota、Gotoh Shiho、Mori Kohji、Ikeda Manabu、Paillard Luc、Morihara Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 721 Pages: 150025-150025
- DOI
  10.1016/j.bbrc.2024.150025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07347, KAKENHI-PROJECT-23K21405, KAKENHI-PROJECT-23K24229, KAKENHI-PROJECT-23K24682, KAKENHI-PROJECT-22K19500
[Journal Article] New Insights of a Neuronal Peptidase DINE/ECEL1: Nerve Development, Nerve Regeneration and Neurogenic Pathogenesis2018
- Author(s)
  Kiryu-Seo Sumiko、Nagata Kenichi、Saido Takaomi C.、Kiyama Hiroshi
- Journal Title
  
  Neurochemical Research
  
  Volume: － Issue: 6 Pages: 1279-1288
- DOI
  10.1007/s11064-018-2665-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15379, KAKENHI-PROJECT-18H02524
[Journal Article] ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis2016
- Author(s)
  Kenichi Nagata, Sumiko Kiryu-Seo, Hiromi Tamada, Fumi Okuyama-Uchimura, Hiroshi Kiyama, Takaomi C. Saido
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 印刷中 Issue: 1 Pages: 1-16
- DOI
  10.1007/s00401-016-1554-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860141, KAKENHI-PLANNED-23111007
[Presentation] 疾患関連ミクログリアの動態解明を目指した in vivo標識ツールの開発2024
- Author(s)
  永田健一
- Organizer
  第97回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07347
[Presentation] アルツハイマー病脳における炎症細胞の動態解明を目指したin vivo標識ツールの開発2024
- Author(s)
  永田健一
- Organizer
  第47回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07347
[Presentation] 神経炎症ミクログリアの動態解明に向けたin vivo標識ツールの確立2024
- Author(s)
  永田健一
- Organizer
  第43回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07347
[Presentation] 神経損傷により惹起された炎症関連細胞の時空間的解析2023
- Author(s)
  永田健一
- Organizer
  第128回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-22K07347
[Presentation] 点変異ノックインマウスの作出による疾患発症機序の探索2020
- Author(s)
  永田健一
- Organizer
  第125回日本解剖学会総会・全国学術集会（誌上開催）
- Data Source
  KAKENHI-PROJECT-18K15379
[Presentation] ECEL1/DINE遺伝子におけるミスセンス変異の in vivo機能解析2019
- Author(s)
  永田健一、木山博資、西道隆臣
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K15379
[Presentation] Conditional targeting of DINE using CRISPR/Cas9 technology in mice2018
- Author(s)
  Kenichi Nagata, Mika Takahashi, and Takaomi C. Saido
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K15379
[Presentation] Generation of ECEL1-mutated distal arthrogyposis model mice using CRISPR/Cas9 system2016
- Author(s)
  Kenichi Nagata, Mika Takahashi, and Takaomi C. Saido
- Organizer
  日本ゲノム編集学会第1回大会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26860141
[Presentation] Aberrant axonal arborization of motor nerves in Damage-Induced Neuronal Endopeptidase deficient limb
- Author(s)
  Kenichi Nagata, Sumiko Kiryu-Seo, Hiroshi Kiyama, Takaomi C Saido
- Organizer
  Cold Spring Harbor Laboratory meeting
- Place of Presentation
  New York
- Year and Date
  2014-09-16 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-26860141

1. 吉見一人 (50709813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 村山繁雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 橘逸勢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 森康治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGATA KENICHI 永田 健一

Nagata Kenichi 永田 健一

永田 健一 ナガタ ケンイチ

Research Projects

Research Products

Co-Researchers

アルツハイマー病における老化した疾患関連ミクログリアの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of in vivo labeling system for long-term tracking of inflammation-related microgliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenic mechanism of congenital contracture disorder with ECEL1/DINE deficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Morphological analyses of aberrant muscle innervation in DINE-deficient motor nervesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経再生関連microRNAの探索および機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tau Accumulation Induces Microglial State Alterations in Alzheimer’s Disease Model Mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] eIF5 stimulates the CUG initiation of RAN translation of poly-GA dipeptide repeat protein (DPR) in C9orf72 FTLD/ALS2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Production of a heterozygous exon skipping model of common marmosets using gene-editing technology2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene-gene functional relationships in Alzheimer's disease: CELF1 regulates KLC1 alternative splicing2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New Insights of a Neuronal Peptidase DINE/ECEL1: Nerve Development, Nerve Regeneration and Neurogenic Pathogenesis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 疾患関連ミクログリアの動態解明を目指した in vivo標識ツールの開発2024

Author(s)

Organizer

Data Source

[Presentation] アルツハイマー病脳における炎症細胞の動態解明を目指したin vivo標識ツールの開発2024

Author(s)

Organizer

Data Source

[Presentation] 神経炎症ミクログリアの動態解明に向けたin vivo標識ツールの確立2024

Author(s)

Organizer

Data Source

[Presentation] 神経損傷により惹起された炎症関連細胞の時空間的解析2023

Author(s)

NAGATA KENICHI 永田健一

Nagata Kenichi 永田健一

永田健一ナガタケンイチ