Niwa Tatsuya 丹羽達也

… Alternative Names

NIWA Tatsuya 丹羽達也

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Researcher Number	50588530
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 助教
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 総合研究院, 助教 2024: 東京工業大学, 科学技術創成研究院, 助教 2020 – 2022: 東京工業大学, 科学技術創成研究院, 助教 2017 – 2018: 東京工業大学, 科学技術創成研究院, 助教 2012 – 2014: 東京工業大学, 生命理工学研究科, 助教 2010 – 2011: 東京工業大学, 大学院・生命理工学研究科, 助教
Review Section/Research Field	Principal Investigator Biophysics / Basic Section 43040:Biophysics-related / Basic Section 43020:Structural biochemistry-related / Structural biochemistry / Biological Sciences Except Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Basic Section 43020:Structural biochemistry-related / Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator フォールディング / タンパク質フォールディング / 無細胞タンパク質合成系 / 分子シャペロン / プロテオーム / ショットガンプロテオミクス / タンパク質凝集 / プロテアーゼ / 分子混み合い / 質量分析 … More / 質量分析装置 / 試験管内分子進化 / 発現制御 / 蛋白質 / 翻訳共役的フォールディング / タンパク質翻訳 / 網羅解析 / タンパク質の凝集 / タンパク質のフォールディング … More Except Principal Investigator 人工知能 / プロテオミクス / 光ピンセット / ソーター / 疾患凝集体 / 過渡構造 / シャペロン / タンパク質フォールディング / RNA結合タンパク質 / 細胞核 / RNA複合体 / 核内構造体 / 液液相分離 Less

化学・計測・数理の融合によるタンパク質フォールディングの過渡構造解析
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokushima
液滴から疾患凝集体への転移を防ぐタンパク質の網羅的探索
- Principal Investigator
  
  鎌形清人
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Gifu University
核内相分離構造体の骨格となるRNAと生理機能の解明
- Principal Investigator
  
  萬年太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Ritsumeikan University
Development and application of a comprehensive method for proteome-wide protein conformational state analysisPrincipal Investigator
- Principal Investigator
  
  丹羽達也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Tokyo Institute of Technology
Establishment of protein folding evolution using cell-free protein synthesis and peptide tagsPrincipal Investigator
- Principal Investigator
  
  Niwa Tatsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Tokyo Institute of Technology
Influence of the change in the dynamics of the protein translation on the translation-coupled foldingPrincipal Investigator
- Principal Investigator
  
  Niwa Tatsuya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo Institute of Technology
Global aggregation analysis of eukaryotic proteins.Principal Investigator
- Principal Investigator
  
  NIWA Tatsuya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Tokyo Institute of Technology
発現量の少ないタンパク質の凝集性とシャペロン要求性の解析Principal Investigator
- Principal Investigator
  
  丹羽達也
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
Global analysis of aggregation-inhibition effects of molecular chaperonesPrincipal Investigator
- Principal Investigator
  
  NIWA Tatsuya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biophysics
- Research Institution
  Tokyo Institute of Technology

All 2023 2022 2021 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Prediction of chaperonin GroE substrates using small structural patterns of proteins2023
- Author(s)
  Minami Shintaro、Niwa Tatsuya、Uemura Eri、Koike Ryotaro、Taguchi Hideki、Ota Motonori
- Journal Title
  
  FEBS Open Bio
  
  Volume: 13 Issue: 4 Pages: 779-794
- DOI
  10.1002/2211-5463.13590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06519, KAKENHI-PLANNED-20H05932
[Journal Article] A method to enrich polypeptidyl-tRNAs to capture snapshots of translation in the cell2023
- Author(s)
  Yamakawa Ayako、Niwa Tatsuya、Chadani Yuhei、Kobo Akinao、Taguchi Hideki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 5 Pages: e30-e30
- DOI
  10.1093/nar/gkac1276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06519, KAKENHI-PROJECT-21H04763
[Journal Article] Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli2022
- Author(s)
  Niwa Tatsuya、Chadani Yuhei、Taguchi Hideki
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 12 Pages: 3772-3772
- DOI
  10.3390/molecules27123772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-20K06519, KAKENHI-PROJECT-21H04763
[Journal Article] Global analysis of chaperone effects using a reconstituted cell-free translation system Proceedings of the National Academy of Sciences of the United States of America2012
- Author(s)
  Tatsuya Niwa, Takashi Kanamori, Takuya Ueda, Hideki Taguchi
- Journal Title
  
  Early Edition
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22870010
[Journal Article] 網羅的解析から見えてきたタンパク質の凝集特性とシャペロンの役割2012
- Author(s)
  丹羽達也、田口英樹
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 70 Pages: 448-452
- NAID
  10031127514
- Data Source
  KAKENHI-PUBLICLY-24115504
[Journal Article] Global Analysis of Chaperone Effects Using a Reconstituted Cell-Free Translation System2012
- Author(s)
  Niwa, T., Kanamori T, Ueda, T.*, Taguchi, H.*
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 109 Issue: 23 Pages: 8937-8942
- DOI
  10.1073/pnas.1201380109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058002, KAKENHI-PROJECT-23247013, KAKENHI-PROJECT-24657070, KAKENHI-PUBLICLY-24115504
[Journal Article] Amphiphilic Polysaccharide Nanogels as Artificial Chaperones in Cell-Free Protein Synthesis.2011
- Author(s)
  Yoshihiro Sasaki, Wakiko Asayama, Tatsuya Niwa, Shin-ichi Sawada, Takuya Ueda, Hideki Taguchi, Kazunari Akiyoshi
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 7 MAR. (EarlyView)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22870010
[Journal Article] Difference in the distribution pattern of substrate enzymes in the metabolic network of Escherichia coli, according to chaperonin requirement2011
- Author(s)
  Kazuhiro Takemoto, Tatsuya Niwa, Hideki Taguchi
- Journal Title
  
  BMC Systems Biology
  
  Volume: 5 Pages: 98-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22870010
[Journal Article] Amphiphilic Polysaccharide Nanogels as Artificial Chaperones in Cell-Free Protein Synthesis2011
- Author(s)
  Yoshihiro Sasaki, Wakiko Asayama, Tatsuya Niwa, Shin-ichi Sawada, Takuya Ueda, Hideki Taguchi, Kazunari Akiyoshi
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 11(6) Pages: 814-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22870010
[Presentation] 定量プロテオミクスを用いた大腸菌GroE依存基質のGroE欠乏条件下における分解機構の解析2022
- Author(s)
  丹羽　達也、茶谷　悠平、田口　英樹
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20K06519
[Presentation] 細胞内の翻訳反応のスナップショットを得るための網羅的ペプチジルtRNA検出法の構築2022
- Author(s)
  山川絢子、丹羽達也、茶谷悠平、田口英樹
- Organizer
  日本プロテオーム学会2022年大会
- Data Source
  KAKENHI-PROJECT-20K06519
[Presentation] ペプチドタグとLC-MS/MSを用いたタンパク質フォールディングの進化実験の確立2021
- Author(s)
  水城真智子、田口英樹、丹羽達也
- Organizer
  「細胞を創る」研究会14.0
- Data Source
  KAKENHI-PROJECT-20K06519
[Presentation] 再構築型生体外タンパク質合成系を用いた分子シャペロンによる凝集抑制効果の大規模解析2012
- Author(s)
  丹羽達也
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学　東山キャンパス
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PUBLICLY-24115504
[Presentation] 無細胞蛋白質合成系を利用した蛋白質凝集の網羅的解析2011
- Author(s)
  丹羽達也、上田卓也、田口英樹
- Organizer
  公開シンポジウム「蛋白質の機能を解き明かす多彩なアプローチ」(招待講演)
- Place of Presentation
  横浜市立大学鶴見キャンパス
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22870010
[Presentation] 無細胞蛋白質合成系を利用した蛋白質凝集の網羅的解析2011
- Author(s)
  丹羽達也
- Organizer
  公開シンポジウム「蛋白質の機能を解き明かす多彩なアプローチ」
- Place of Presentation
  横浜市立大学鶴見キャンパス(招待講演)
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22870010
[Presentation] 再構築型生体外蛋白質合成系を用いた分子シャペロンによる凝集抑制効果の網羅解析2010
- Author(s)
  丹羽達也、上田卓也、田口英樹
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22870010
[Presentation] 出芽酵母の凝集性タンパク質に対するシャペロンの可溶化効果
- Author(s)
  上村英里、丹羽達也、上田卓也、田口英樹
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25840045
[Presentation] 再構築型無細胞タンパク質合成系を用いた出芽酵母タンパク質の凝集性の解析
- Author(s)
  丹羽達也
- Organizer
  第9回無細胞生命科学研究会
- Place of Presentation
  大阪大学医学部　銀杏会館
- Year and Date
  2014-10-08 – 2014-10-09
- Data Source
  KAKENHI-PROJECT-25840045

1. TAGUCHI Hideki (40272710)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. 萬年太郎 (50535763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 田岡万悟 (60271160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 齋尾智英 (80740802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐藤伸一 (20633134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鎌形清人 (90432492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小池亮太郎 (20381577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Chadani Yuhei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Iwasaki Shintaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Niwa Tatsuya 丹羽 達也

NIWA Tatsuya 丹羽 達也

Research Projects

Research Products

Co-Researchers

化学・計測・数理の融合によるタンパク質フォールディングの過渡構造解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

液滴から疾患凝集体への転移を防ぐタンパク質の網羅的探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

核内相分離構造体の骨格となるRNAと生理機能の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and application of a comprehensive method for proteome-wide protein conformational state analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of protein folding evolution using cell-free protein synthesis and peptide tagsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Influence of the change in the dynamics of the protein translation on the translation-coupled foldingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Global aggregation analysis of eukaryotic proteins.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

発現量の少ないタンパク質の凝集性とシャペロン要求性の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Global analysis of aggregation-inhibition effects of molecular chaperonesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prediction of chaperonin GroE substrates using small structural patterns of proteins2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A method to enrich polypeptidyl-tRNAs to capture snapshots of translation in the cell2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global analysis of chaperone effects using a reconstituted cell-free translation system Proceedings of the National Academy of Sciences of the United States of America2012

Author(s)

Journal Title

Data Source

[Journal Article] 網羅的解析から見えてきたタンパク質の凝集特性とシャペロンの役割2012

Author(s)

Niwa Tatsuya 丹羽達也

NIWA Tatsuya 丹羽達也

[Presentation] 細胞内の翻訳反応のスナップショットを得るための網羅的ペプチジルtRNA検出法の構築2022

[Presentation] 再構築型生体外タンパク質合成系を用いた分子シャペロンによる凝集抑制効果の大規模解析2012