Yamaguchi Soichiro 山口聡一郎

… Alternative Names

山口聡一郎ヤマグチソウイチロウ

YAMAGUCHI Soichiro 山口聡一郎

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Researcher Number	50596864
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 獣医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 北海道大学, 獣医学研究院, 准教授 2018 – 2019: 北海道大学, 獣医学研究院, 准教授 2017: 北海道大学, 獣医学研究院, 助教 2016: 北海道大学, 獣医学研究科, 助教 2016: 北海道大学, 大学院獣医学研究科, 助教 … More 2015: 北海道大学, (連合)獣医学研究科, 助教 2014: 北海道大学, 獣医学研究科, 助教 2012: 北海道大学, (連合)獣医学研究科, 特任助教 2012: 北海道大学, 大学院・獣医学研究科, 特任助教 2011: 新潟大学, 医歯学系, 助教 Less
Review Section/Research Field	Principal Investigator Integrative animal science / Basic Section 48020:Physiology-related / General physiology Except Principal Investigator Integrative animal science
Keywords	Principal Investigator 生理学 / 褐色脂肪 / プロトンチャネル / 膜タンパク質 / タンパク質分解 / タンパク質切断 / 核内移行 / 転写調節 / TMC1 / 触覚受容器 … More / 機械受容チャネル / 内耳蝸牛 / NBCe1-B / 重炭酸イオントランスポーター / 陽イオンチャネル / 血管条 / 内耳 … More Except Principal Investigator アデノシンキナーゼ / ギャップジャンクションヘミチャネル / 平衡ヌクレオチド輸送体 / 平衡ヌクレオシド輸送体 / シスタチオンβシンターゼ / シスタチオニンβシンターゼ / 低酸素 / グリア伝達物質 / 脊髄 / 硫化水素 / アデノシン / アストロサイト Less

熱産生する褐色脂肪細胞に新規H+チャネルが高発現する生理的意義の解明Principal Investigator
- Principal Investigator
  
  山口聡一郎
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Hokkaido University
Research on a possible novel transcriptional regulation by a membrane proteinPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Soichiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Hokkaido University
Molecular mechanisms of pleasant tactile sensation.Principal Investigator
- Principal Investigator
  
  YAMAGUCHI Soichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Integrative animal science
- Research Institution
  Hokkaido University
Gliotransmitter release and its protective effects in spinal astrocytes
- Principal Investigator
  
  Otsuguro Ken-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Hokkaido University
Research on the system of pH regulation in endocochlear epitheliumPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Soichiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Hokkaido University
  Niigata University

All 2024 2023 2022 2020 2019 2016 2015

All Journal Article Presentation

[Journal Article] Cibacron blue 3G-A is a novel inhibitor of Otopetrin 1 (OTOP1), a proton channel.2023
- Author(s)
  Islam MM, Sasaki O, Yano-Nashimoto S, Okamatsu-Ogura Y, Yamaguchi S.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 665 Pages: 64-70
- DOI
  10.1016/j.bbrc.2023.04.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06825
[Journal Article] Endogenous 5-HT outflow from chicken aorta by 5-HT uptake inhibitors and amphetamine derivatives2016
- Author(s)
  Delgermurun D, Ito S, Ohta T, Yamaguchi S, Otsuguro K
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 78 Issue: 1 Pages: 71-76
- DOI
  10.1292/jvms.15-0146
- NAID
  130005121579
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26450440
[Journal Article] Hydrogen sulfide activates TRPA1 and releases 5-HT from epithelioid cells of the chicken thoracic aorta.2016
- Author(s)
  Delgermurun D, Yamaguchi S, Ichii O, Kon Y, Ito S, Otsuguro K
- Journal Title
  
  Comp. Biochem. Physiol. C Toxicol. Pharmacol.
  
  Volume: 187 Pages: 43-49
- NAID
  120006337745
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450440
[Journal Article] Contribution of α2A-adrenoceptor subtype to effect of dexmedetomidine and xylazine on spinal synaptic transmission of mice2015
- Author(s)
  Takeshi Kobayashi, Ken-ichi Otsuguro, Soichiro Yamaguchi, Shigeo Ito
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 761 Pages: 321-329
- DOI
  10.1016/j.ejphar.2015.06.020
- NAID
  120005825580
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450440
[Journal Article] Different mechanisms of extracellular adenosine accumulation by reduction of the external Ca2+ concentration and inhibition of adenosine metabolism in spinal astrocytes.2015
- Author(s)
  Ryota Eguchi, Sanae Akao, Ken-ichi Otsuguro, Soichiro Yamaguchi, Shigeo Ito
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 印刷中
- NAID
  120005661436
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450440
[Journal Article] Neuronal regulation of hydrogen sulfide-producing enzyme cystathionine β-synthase expression in rat spinal cord astrocytes.2015
- Author(s)
  Ｒｙｏ　Miyamoto, Ｋｅｎ－ｉｃｈｉ　Otsuguro, Ｓｏｉｃｈｉｒｏ　Yamaguchi, Ｓｈｉｇｅｏ　Ito
- Journal Title
  
  Ｎｅｕｒｏｓｃｉｅｎｃｅ　Ｒｅｓｅａｒｃｈ
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450440
[Journal Article] An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat2015
- Author(s)
  Ken-ichi Otsuguro, Yuki Tomonari, Saori Otsuka, Soichiro Yamaguchi, Yasuhiro Kon, Shigeo Ito
- Journal Title
  
  Neuropharmacology
  
  Volume: 97 Pages: 160-170
- DOI
  10.1016/j.neuropharm.2015.05.035
- NAID
  120005906926
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450440
[Journal Article] Bidirectional effects of hydrogen sulfide via ATP-sensitive K+ channels and transient receptor potential A1 channels in RIN14B cells2015
- Author(s)
  Ayako Ujike, Ken-ichi Otsuguro K, Ryo Miyamoto, Soichiro Yamaguchi, Shigeo Ito
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 764 Pages: 463-470
- DOI
  10.1016/j.ejphar.2015.07.029
- NAID
  120005906928
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] A novel inhibitor of OTOP1, a proton (H+) channel, was identified by screening of a chemical library2024
- Author(s)
  Soichiro Yamaguchi, MD Mominul Islam, Omi Sasaki, Saori Yano-Nashimoto, and Yuko Okamatsu-Ogura
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06825
[Presentation] Discovery of Cibacron Blue 3G-A as an inhibitor of a proton channel, Otopetrin 1 (OTOP1)2023
- Author(s)
  MD Mominul Islam, Omi Sasaki, Saori Yano-Nashimoto, Yuko Okamatsu-Ogura, and Soichiro Yamaguchi
- Organizer
  Sapporo Summer Symposium for One Health (SaSSOH) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06825
[Presentation] プロトン（H+）チャネルOTOP1における糖鎖付加の検討2023
- Author(s)
  佐々木雄望, 矢野（梨本）沙織, 山口聡一郎
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06825
[Presentation] Identification of Cibacron Blue 3G-A as an inhibitor of Otopetrin 1 (OTOP1), a sour sensing proton channel2023
- Author(s)
  MD Mominul Islam, Omi Sasaki, Saori Yano-Nashimoto, Yuko Okamatsu-Ogura, and Soichiro Yamaguchi
- Organizer
  The 20th International Symposium on Molecular andNeural mechanisms of Taste and Olfactory Perception
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06825
[Presentation] プロトン（H+）チャネルOTOP1の新規阻害薬の発見2023
- Author(s)
  Islam MD Mominul, 矢野（梨本）沙織, 岡松優子, 山口聡一郎
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06825
[Presentation] Evaluation of Otopetrin-1 (Otop1) expression in brown adipose tissue2022
- Author(s)
  MD Mominul ISLAM, Omi SASAKI, Saori YANO, Yuko OKAMATSU-OGURA and Soichiro YAMAGUCHI
- Organizer
  SaSSOH 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06825
[Presentation] A cytosolic N-terminal region of Transmembrane Channel-like protein 1 (TMC1) is cleaved and imported into the nucleus in an overexpression system2020
- Author(s)
  Soichiro Yamaguchi, Maho Kamino, Maho Hamamura, and Ken-ichi Otsuguro
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08066
[Presentation] TMC1の細胞内N端領域における核移行機序および切断部位の同定2019
- Author(s)
  神野真帆、濱村眞帆、山口聡一郎、乙黒兼一
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08066
[Presentation] Extracellular accumulation of adenosine by ischemic stimulations in rat spinal astrocytes2016
- Author(s)
  江口遼太、山口聡一郎、乙黒兼一
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] H2S releases 5-HT via activation of TRPA1 in chemoreceptor cells of chicken thoracic aorta2016
- Author(s)
  Dugar DELGERMURUN, Soichiro YAMAGUCHI, Osamu ICHII, Yasuhiro KON, Shigeo ITO, Ken-ichi OTSUGURO
- Organizer
  第30回北海道薬物作用談話会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2016-07-31
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] Multiple ischemic like stimuli increase extracellular adenosine in rat spinal astrocytes2016
- Author(s)
  Ryota Eguchi, Soichiro Yamaguchi, Ken-ichi Otsuguro
- Organizer
  The 4th Sapporo Summer Seminar for One Health (SaSSOH)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] Effect of H2S on 5-HT release from glomus cells in the chicken thoracic aorta2016
- Author(s)
  DELGERUMURUN Dugar, 山口聡一郎, 市居修、昆泰寛、伊藤茂男、乙黒兼一
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学（藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] Ischemic stimuli induce extracellular accumulation of adenosine in rat spinal cord2016
- Author(s)
  Ryota Eguchi, Soichiro Yamaguchi, Ken-ichi Otsuguro
- Organizer
  第59回日本神経化学大会
- Place of Presentation
  福岡国際会議場（福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] H2S-induced Ca2+ signals are increased by IL-1β in RIN-14B cells2016
- Author(s)
  Ayako Ujike, Soichiro Yamaguchi, Shigeo Ito, Ken-ichi Otsuguro
- Organizer
  The 4th Sapporo Summer Seminar for One Health (SaSSOH)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] MrgprB4陽性後根神経節神経における細胞膨張によるCa2+流入経路2016
- Author(s)
  山口聡一郎、乙黒兼一
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌市
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26850204
[Presentation] Effect of pro-inflammatory cytokine on H2S-induced Ca2+ responses in RIN14B cells2016
- Author(s)
  氏家絢子、山口聡一郎、伊藤茂男、乙黒兼一
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] H2S releases 5-HT from chicken thoracic chemoreceptor cells via the activation of TRPA12016
- Author(s)
  Dugar Delgermurun, Soichiro Yamaguchi, Osamu Ichii, Yasuhiro Kon, Shigeo Ito, Ken-ichi Otsuguro
- Organizer
  The 4th Sapporo Summer Seminar for One Health (SaSSOH)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] IL-1β enhances H2S-induced Ca2+ responses and 5-HT release in RIN14B cells2016
- Author(s)
  Ayako Ujike, Soichiro Yamaguchi, Shigeo Ito, Ken-ichi Otsuguro
- Organizer
  第59回日本神経化学大会
- Place of Presentation
  福岡国際会議場（福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] ラット脊髄における硫化水素産生酵素CBSの発現はニューロンにより維持される2015
- Author(s)
  宮本亮、乙黒兼一、山口聡一郎、伊藤茂男
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] Ca2+ reduction accumulates extracellular adenosine in spinal cord2015
- Author(s)
  Ryota Eguchi, Sanae Masumoto, Soichiro Yamaguchi, Shigeo Ito, Ken-ichi Otsuguro
- Organizer
  The 3rd Sapporo Summer Seminar for One Health (SaSSOH)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] Isolation of 5-HT-containing cells using fluorescence activated cell sorter2015
- Author(s)
  Ayako Ujike, Soichiro Yamaguchi, Shigeo Ito, Ken-ichi Otsuguro
- Organizer
  The 3rd Sapporo Summer Seminar for One Health (SaSSOH)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] ニューロンによるラット脊髄アストロサイトの硫化水素産生酵素の発現調節2015
- Author(s)
  宮本亮、乙黒兼一、山口聡一郎、伊藤茂男
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学（十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-26450440
[Presentation] Estimate the cause of the species difference of the effectiveness of xylazine by docking simulation2015
- Author(s)
  Takeshi Kobayashi, Soichiro Yamaguchi, Yoshihiro Ikenaka, Shigeo Ito, Ken-ichi Otsuguro
- Organizer
  The 3rd Sapporo Summer Seminar for One Health (SaSSOH)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450440

1. HIBINO Hiroshi (70314317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YAMAGUCHI Kenichi (50108023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Otsuguro Ken-ichi (40344494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
4. 岡松優子 (90527178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Yamaguchi Soichiro 山口 聡一郎

山口 聡一郎 ヤマグチ ソウイチロウ

YAMAGUCHI Soichiro 山口 聡一郎

Research Projects

Research Products

Co-Researchers

熱産生する褐色脂肪細胞に新規H+チャネルが高発現する生理的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on a possible novel transcriptional regulation by a membrane proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of pleasant tactile sensation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gliotransmitter release and its protective effects in spinal astrocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the system of pH regulation in endocochlear epitheliumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cibacron blue 3G-A is a novel inhibitor of Otopetrin 1 (OTOP1), a proton channel.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endogenous 5-HT outflow from chicken aorta by 5-HT uptake inhibitors and amphetamine derivatives2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Hydrogen sulfide activates TRPA1 and releases 5-HT from epithelioid cells of the chicken thoracic aorta.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Contribution of α2A-adrenoceptor subtype to effect of dexmedetomidine and xylazine on spinal synaptic transmission of mice2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Different mechanisms of extracellular adenosine accumulation by reduction of the external Ca2+ concentration and inhibition of adenosine metabolism in spinal astrocytes.2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Neuronal regulation of hydrogen sulfide-producing enzyme cystathionine β-synthase expression in rat spinal cord astrocytes.2015

Author(s)

Journal Title

Data Source

[Journal Article] An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Bidirectional effects of hydrogen sulfide via ATP-sensitive K+ channels and transient receptor potential A1 channels in RIN14B cells2015

Author(s)

Journal Title

DOI

NAID

Yamaguchi Soichiro 山口聡一郎

山口聡一郎ヤマグチソウイチロウ

YAMAGUCHI Soichiro 山口聡一郎