Ito Shinsuke 伊藤伸介

… Alternative Names

Researcher Number	50612115
Other IDs
Affiliation (Current)	2021: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員
Affiliation (based on the past Project Information) *help	2021: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2018 – 2019: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2015 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員 2013: 独立行政法人理化学研究所, 統合生命医科学研究センター, 基礎科学特別研究員 2012: 独立行政法人理化学研究所, その他部局等, 研究員 2011 – 2012: 独立行政法人理化学研究所, 免疫器官形成研究グループ, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Genetics/Genome dynamics / Biological Sciences / Genetics/Chromosome dynamics / Basic Section 43050:Genome biology-related Except Principal Investigator Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator 遺伝子発現抑制 / ポリコーム / エピジェネティクス / CpGアイランド / ポリコーム群 / CXXCドメイン / DNA脱メチル化 / H3K4me3 / CXXC1 / ユビキチン … More Except Principal Investigator Enhancer / H4K5acK8ac / Epigenomics Less

Redefinition of enhancers by the histone H4 hyperacetylationOngoing
- Principal Investigator
  
  DAS NANDO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Institute of Physical and Chemical Research
ユビキチン-プロテアソーム系を介したCpGアイランドの制御機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  伊藤伸介
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Institute of Physical and Chemical Research
Elucidation of an epigenetic hierarchy mediated by CXXC proteinsPrincipal Investigator
- Principal Investigator
  
  ITO SHINSUKE
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Institute of Physical and Chemical Research
ＣｐＧアイランドを制御するＣＸＸＣタンパク質の機能解析Principal Investigator
- Principal Investigator
  
  伊藤伸介
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
ポリコーム群の標的特異性決定メカニズムの解析Principal Investigator
- Principal Investigator
  
  伊藤伸介
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  The Institute of Physical and Chemical Research

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 細胞工学、ポリコーム複合体によるエピゲノム制御2015
- Author(s)
  伊藤伸介, 古関明彦
- Total Pages
  5
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-15H05602
[Book] イラストで徹底理解するエピジェネティクスキーワード事典2014
- Author(s)
  伊藤伸介
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-24114519
[Journal Article] Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression.2019
- Author(s)
  Fursova NA, Blackledge NP, Nakayama M, Ito S, Koseki Y, Farcas AM, King HW, Koseki H, Klose RJ.
- Journal Title
  
  Molecular Cell
  
  Volume: 印刷中 Pages: 1020-1036
- DOI
  10.1016/j.molcel.2019.03.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-19K06621, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities2018
- Author(s)
  Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP.
- Journal Title
  
  Molecular Cell
  
  Volume: 70 Pages: 408-421
- DOI
  10.1016/j.molcel.2018.03.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-16H02622
[Journal Article] 1.PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes2017
- Author(s)
  Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose RJ, Koseki H.
- Journal Title
  
  Elife.
  
  Volume: 6 Pages: 27970-27970
- DOI
  10.7554/elife.21064
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K14773, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-26221309
[Journal Article] The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin2017
- Author(s)
  Brown DA, Di Cerbo V, Feldmann A, Ahn J, Ito S, Blackledge NP, Nakayama M, McClellan M, Dimitrova E, Turberfield AH, Long HK, King HW, Kriaucionis S, Schermelleh L, Kutateladze T, Koseki H, Klose RJ.
- Journal Title
  
  Cell Rep.
  
  Volume: 20 Pages: 2313-2327
- DOI
  10.1016/j.celrep.2017.08.030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602
[Journal Article] Polycomb in Transcriptional Phase Transition of Developmental Genes2016
- Author(s)
  Kondo, T., Koseki, H. and Ito, S.
- Journal Title
  
  Trends Biochem. Sci.
  
  Volume: 41 Pages: 9-19
- DOI
  10.1016/j.tibs.2015.11.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15076, KAKENHI-PROJECT-15H05602
[Journal Article] Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.2015
- Author(s)
  Ito S, Kuraoka I
- Journal Title
  
  DNA Repair
  
  Volume: 32 Pages: 52-57
- DOI
  10.1016/j.dnarep.2015.04.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-26650006, KAKENHI-PROJECT-25281018
[Journal Article] Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation2014
- Author(s)
  Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LLP, Ito S, Cooper S, Kondo K, Koseki Y, Ishikura T, Long HK, Sheahan TW, Brockdorff N, Kessler BM, Koseki H, Klose RJ.
- Journal Title
  
  Cell
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24114519
[Journal Article] Embracing change to remain the same: conservation of polycomb functions despite divergence of binding motifs among species2013
- Author(s)
  Jafar Sharif, Takaho A Endo, Shinsuke Ito, Osamu Ohara, Haruhiko Koseki
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 25 Pages: 305-313
- DOI
  10.1016/j.ceb.2013.02.009
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24114519
[Journal Article] Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells2011
- Author(s)
  Wu H, D'Alessio AC, Ito S, Xia K, Wang Z, Cui K, Zhao K, Sun Y, Zhang Y
- Journal Title
  
  Nature
  
  Volume: 473 Pages: 389-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23870038
[Journal Article] Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine2011
- Author(s)
  Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y
- Journal Title
  
  Science
  
  Volume: 333 Pages: 1300-1303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23870038
[Journal Article] Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells2011
- Author(s)
  Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, Sun Y, Zhang Y
- Journal Title
  
  Genes and Development
  
  Volume: 25 Pages: 679-684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23870038
[Presentation] ポリコーム複合体PRC1.1によるCpGアイランドのエピゲノム制御2019
- Author(s)
  伊藤伸介
- Organizer
  第2回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-15H05602
[Presentation] Polycomb-proteasome axis shapes the epigenetic landscape of CpG islands2019
- Author(s)
  伊藤伸介
- Organizer
  エピジェネティクス研究会
- Data Source
  KAKENHI-PROJECT-19K06621
[Presentation] ポリコーム複合体PRC1.1によるCpGアイランドのエピゲノム制御2018
- Author(s)
  伊藤伸介
- Organizer
  第41回日本分子生物学会年会ワークショップ
- Data Source
  KAKENHI-PROJECT-15H05602
[Presentation] Role of CXXC1 in transcriptional regulation and cell-fate decision2016
- Author(s)
  Shinsuke Ito, Marika Shibata, Takashi Kondo and Haruhiko Koseki
- Organizer
  Kick-off symposium in Nagoya City University 2016
- Place of Presentation
  Nagoya City University Hospital
- Year and Date
  2016-02-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05602
[Presentation] Role of CXXC1 in transcriptional regulation and cell-fate decision2016
- Author(s)
  Shinsuke Ito, Marika Shibata, Hiroki Sugishita, Takashi Kondo, and Haruhiko Koseki
- Organizer
  EMBL Conference: Transcription and Chromatin
- Place of Presentation
  EMBLハイデルベルグ、ドイツ
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05602
[Presentation] 哺乳動物におけるDNAメチル化のダイナミクス2013
- Author(s)
  伊藤伸介
- Organizer
  日本生化学会第93春季年会
- Place of Presentation
  滋賀
- Year and Date
  2013-03-22
- Invited
- Data Source
  KAKENHI-PUBLICLY-24114519
[Presentation] Tet タンパク質による酸化的DNA 脱メチル化経路の解析2012
- Author(s)
  伊藤伸介
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪
- Year and Date
  2012-09-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-24114519
[Presentation] Tet タンパク質を介したDNA 脱メチル化経路の解析2012
- Author(s)
  伊藤伸介
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2012-05-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-24114519
[Presentation] Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine2011
- Author(s)
  Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23870038
[Presentation] Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication
- Author(s)
  Shinsuke Ito, Toshihiro Shibutani, Marika Shibata, Shigenori Iwai, Haruhiko Koseki, Isao Kuraoka
- Organizer
  Firtst meeting on RIKEN Epigenetics
- Place of Presentation
  Riken Yokohama
- Data Source
  KAKENHI-PUBLICLY-24114519

1. DAS NANDO (20731756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. MASUI Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 古関明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 須田年生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 遠藤充浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 近藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 倉岡功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Shinsuke 伊藤 伸介

伊藤 伸介 イトウ シンスケ

ITO SHINSUKE 伊藤 伸介

Research Projects

Research Products

Co-Researchers

Redefinition of enhancers by the histone H4 hyperacetylationOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ユビキチン-プロテアソーム系を介したCpGアイランドの制御機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of an epigenetic hierarchy mediated by CXXC proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ＣｐＧアイランドを制御するＣＸＸＣタンパク質の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ポリコーム群の標的特異性決定メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞工学、ポリコーム複合体によるエピゲノム制御2015

Author(s)

Total Pages

Publisher

Data Source

[Book] イラストで徹底理解する エピジェネティクス キーワード事典2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 1.PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polycomb in Transcriptional Phase Transition of Developmental Genes2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation2014

Author(s)

Journal Title

Data Source

Ito Shinsuke 伊藤伸介

伊藤伸介イトウシンスケ

ITO SHINSUKE 伊藤伸介

[Book] イラストで徹底理解するエピジェネティクスキーワード事典2014