OYAMA KEI 小山佳

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Oyama Kei 小山佳

小山佳オヤマケイ

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Researcher Number	50615250
Other IDs
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究センター, 主幹研究員
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究センター, 主任研究員 2022 – 2023: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究部, 主任研究員 2021: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所脳機能イメージング研究部, 研究員 2017 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 研究員(任常) 2016: 東北大学, 生命科学研究科, 助教 2015: 東北大学, 生命科学研究科, 助教(研究特任) 2012: 東北大学, 生命科学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 51020:Cognitive and brain science-related / Transformative Research Areas, Section (III) / Basic / Social brain science / Neurophysiology and muscle physiology
Keywords	Principal Investigator 視床 / 化学遺伝学 / 霊長類 / 線条体 / 前頭前野 / 前頭連合野 / 大脳基底核 / 双方向回路 / rna-seq / サル … More / 試行錯誤 / 先読み / 高次脳機能 / 意思決定 / 報酬 / 経路選択的阻害 / 前頭眼窩野 / 経路選択的機能阻害 / 首輪による非侵襲的訓練 / 報酬の期待 / 刺激の価値 / 報酬予測誤差 / 単一ニューロン活動記録・標識 / 大脳皮質 / ラット Less

Roles of reciprocal circuits connecting the cortex and thalamus for adaptive behaviorPrincipal Investigator
- Principal Investigator
  
  小山佳
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  National Institutes for Quantum Science and Technology
Chemogenetic dissection of the primate prefronto-subcortical pathways for adaptive behaviorPrincipal Investigator
- Principal Investigator
  
  小山佳
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  National Institutes for Quantum Science and Technology
Chemogenetic dissection of the primate prefronto-subcortical pathwaysPrincipal Investigator
- Principal Investigator
  
  Oyama Kei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  National Institutes for Quantum Science and Technology
Chemogenetic dissection of the primate prefronto-subcortical pathways for adaptive behaviorPrincipal Investigator
- Principal Investigator
  
  Oyama Kei
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  National Institutes for Quantum Science and Technology
The role of the basal ganglia in action selection revealed by single-neuron electrophysiological and histological investigationPrincipal Investigator
- Principal Investigator
  
  Oyama Kei
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
  Tohoku University
新規な単一ニューロンの活動記録・染色法を用いた大脳基底核機能の解明Principal Investigator
- Principal Investigator
  
  小山佳
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Multimodal imaging for validation and optimization of ion channel-based chemogenetics in nonhuman primates2023
- Author(s)
  Yuki Hori, Yuji Nagai, Yukiko Hori, Kei Oyama, Koki Mimura, Toshiyuki Hirabayashi, Ken-ichi Inoue, Masayuki Fujinaga, Ming-Rong Zhang, Masahiko Takada, Makoto Higuchi, Takafumi Minamimoto
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 43 Issue: 39 Pages: 6619-6627
- DOI
  10.1523/jneurosci.0625-23.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K11796, KAKENHI-PROJECT-21K07268, KAKENHI-PROJECT-22K19480, KAKENHI-PROJECT-19H01038, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-20H05955, KAKENHI-PLANNED-22H05157, KAKENHI-PUBLICLY-22H05521, KAKENHI-PROJECT-23K27098, KAKENHI-PROJECT-23K27472
[Journal Article] Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections2023
- Author(s)
  Oyama Kei、Nagai Yuji、Minamimoto Takafumi
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 13 Issue: 23
- DOI
  10.21769/bioprotoc.4897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07268, KAKENHI-PLANNED-20H05955, KAKENHI-PUBLICLY-22H05521, KAKENHI-PROJECT-23K27098
[Journal Article] Chemogenetic attenuation of cortical seizures in nonhuman primates2023
- Author(s)
  Miyakawa Naohisa、Nagai Yuji、Hori Yukiko、Mimura Koki、Orihara Asumi、Oyama Kei、Matsuo Takeshi、Inoue Ken-ichi、Suzuki Takafumi、Hirabayashi Toshiyuki、Suhara Tetsuya、Takada Masahiko、Higuchi Makoto、Kawasaki Keisuke、Minamimoto Takafumi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41467-023-36642-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07268, KAKENHI-PROJECT-22K07318, KAKENHI-PROJECT-22K19480, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-20H05955, KAKENHI-PUBLICLY-21H05813, KAKENHI-PLANNED-22H05157, KAKENHI-PUBLICLY-22H05521, KAKENHI-PROJECT-19H01038
[Journal Article] Chronic Behavioral Manipulation via Orally Delivered Chemogenetic Actuator in Macaques2022
- Author(s)
  Oyama Kei、Hori Yukiko、Nagai Yuji、Miyakawa Naohisa、Mimura Koki、Hirabayashi Toshiyuki、Inoue Ken-ichi、Takada Masahiko、Higuchi Makoto、Minamimoto Takafumi
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 42 Issue: 12 Pages: 2552-2561
- DOI
  10.1523/jneurosci.1657-21.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07811, KAKENHI-PROJECT-19K08138, KAKENHI-PROJECT-18K15353, KAKENHI-PROJECT-19H01038, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-20H04596, KAKENHI-PUBLICLY-20H05062, KAKENHI-PUBLICLY-21H05836, KAKENHI-PROJECT-18H04037, KAKENHI-PROJECT-19H03335
[Journal Article] Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action2022
- Author(s)
  Oyama Kei、Hori Yukiko、Mimura Koki、Nagai Yuji、Eldridge Mark A. G.、Saunders Richard C.、Miyakawa Naohisa、Hirabayashi Toshiyuki、Hori Yuki、Inoue Ken-ichi、Suhara Tetsuya、Takada Masahiko、Higuchi Makoto、Richmond Barry J.、Minamimoto Takafumi
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 42 Issue: 32 Pages: 6267-6275
- DOI
  10.1523/jneurosci.0229-22.2022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07268, KAKENHI-PROJECT-22K19480, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-20H05955, KAKENHI-PLANNED-22H05157, KAKENHI-PUBLICLY-22H05521, KAKENHI-PROJECT-19H01038
[Journal Article] Chemogenetic dissection of the primate prefronto-subcortical pathways for working memory and decision-making2021
- Author(s)
  Oyama Kei、Hori Yukiko、Nagai Yuji、Miyakawa Naohisa、Mimura Koki、Hirabayashi Toshiyuki、Inoue Ken-ichi、Suhara Tetsuya、Takada Masahiko、Higuchi Makoto、Minamimoto Takafumi
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 26 Pages: 1-9
- DOI
  10.1126/sciadv.abg4246
- NAID
  120007089253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07811, KAKENHI-PROJECT-18K15353, KAKENHI-PROJECT-19H01038, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-20H04596, KAKENHI-PUBLICLY-20H05062, KAKENHI-PUBLICLY-21H05836, KAKENHI-PROJECT-18H04037, KAKENHI-PROJECT-19H03335, KAKENHI-PROJECT-21K07268
[Journal Article] Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys2020
- Author(s)
  Nagai Yuji, Miyakawa Naohisa et al.
- Journal Title
  
  Nature Neuroscience
  
  Volume: 23 Issue: 9 Pages: 1157-1167
- DOI
  10.1038/s41593-020-0661-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08138, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-18K15353, KAKENHI-PUBLICLY-19H04996, KAKENHI-PROJECT-18H04037, KAKENHI-PROJECT-17H02219
[Journal Article] Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action2019
- Author(s)
  Fujimoto Atsushi、Hori Yukiko、Nagai Yuji、Kikuchi Erika、Oyama Kei、Suhara Tetsuya、Minamimoto Takafumi
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 39 Issue: 10 Pages: 1793-1804
- DOI
  10.1523/jneurosci.2399-18.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15353, KAKENHI-PROJECT-18H04037, KAKENHI-PROJECT-17K13275, KAKENHI-PLANNED-15H05917
[Journal Article] Robust, highly customizable, and economical multi-channel electrode for chronic multi-unit recording in behaving animals2017
- Author(s)
  Tateyama Yukina、Oyama Kei、Shiraishi Masaru、Iijima Toshio、Tsutsui Ken-Ichiro
- Journal Title
  
  Neuroscience Research
  
  Volume: 125 Pages: 54-59
- DOI
  10.1016/j.neures.2017.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K16569, KAKENHI-PROJECT-24223004, KAKENHI-PROJECT-17H01014, KAKENHI-PLANNED-26112009
[Journal Article] Neck collar for restraining head and body movements in rats for behavioral task performance and simultaneous neural activity recording.2016
- Author(s)
  Tateyama Y, Oyama K, Lo CW, Iijima T, Tsutsui KI
- Journal Title
  
  Journal of Neruoscience Methods
  
  Volume: 263 Pages: 68-74
- DOI
  10.1016/j.jneumeth.2016.02.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560455, KAKENHI-PROJECT-15K16569, KAKENHI-INTERNATIONAL-15K21715, KAKENHI-PLANNED-26112009, KAKENHI-PROJECT-24223004
[Journal Article] Discrete coding of stimulus value, reward expectation, and reward prediction error in the dorsal striatum.2015
- Author(s)
  Oyama K, Tateyama Y, Hernadi I, Tobler PN, Iijima T, Tsutsui KI
- Journal Title
  
  Journal of Neurophysiology
  
  Volume: 114 Issue: 5 Pages: 2600-2615
- DOI
  10.1152/jn.00097.2015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560455, KAKENHI-PROJECT-15K16569, KAKENHI-PLANNED-26112009, KAKENHI-PROJECT-24223004
[Presentation] Distinct roles of pathways from monkey orbitofrontal cortex to caudate nucleus and mediodorsal thalamus in value-based adaptive decision-making2022
- Author(s)
  小山　佳
- Organizer
  第4５回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07268
[Presentation] Distinct roles of pathways from monkey orbitofrontal cortex to caudate nucleus and mediodorsal thalamus in value-based adaptive decision-making2022
- Author(s)
  小山佳
- Organizer
  第45回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05521
[Presentation] Chemogenetic dissection of the primate prefronto-subcortical pathways for higher-order functions2021
- Author(s)
  小山　佳
- Organizer
  第4４回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07268
[Presentation] dissection of the primate prefronto-subcortical pathways for higher-order functions2021
- Author(s)
  Kei Oyama
- Organizer
  第44回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15353
[Presentation] DREADDを用いた経路選択的阻害法による、サル前頭前野と視床MD核及び線条体を結ぶ神経経路のワーキングメモリにおける役割の解明2020
- Author(s)
  Kei Oyama, Yukiko Hori, Yuji Nagai, Naohisa Miyakawa, Koki Mimura, Toshiyuki Hirabayashi, Ken-ichi Inoue, Masahiko Takada, Makoto Higuchi, Takafumi Minamimoto
- Organizer
  第43回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15353
[Presentation] DREADDによる、報酬を基にした柔軟な意思決定におけるサル前頭眼窩野とその皮質下領域への経路の役割の解明2019
- Author(s)
  Kei Oyam小山佳, 堀由紀子, 永井裕司, 平林敏行, 宮川尚久, 藤本淳, 三村喬生, 井上謙一, Mark A.G. Eldridge, Richard C Saunders, 須原哲也, 高田昌彦, 樋口真人, Barry J. Richmond, 南本敬史
- Organizer
  日本神経科学学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15353
[Presentation] Inactivation of rat dorsomedial prefrontal cortex or posterior parietal cortex, but not ventromedial prefrontal cortex, impairs the performance of the visuospatial delayed response task.2016
- Author(s)
  Oyama K, Lo CWC, Tateyama Y, Iijima T, Tsutsui KI.
- Organizer
  The 39th annual meeting of the Japan Neuroscience Society
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16569
[Presentation] Morphological identification of rat medial prefrontal neurons showing sustained activity during a delay period of a delayed response task by single-neuron electroporation2015
- Author(s)
  Kei Oyama, Yukina Tateyama, Cheuk Wa Christopher Lo, Shinya Ohara, Fuyuki Karube, Fumino Fujiyama, Toshio Iijima, Ken-Ichiro Tsutsui
- Organizer
  The 38th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Kobe International Conference Center, Kobe
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16569
[Presentation] Cytoarchitectonic information of rat medial prefrontal “delay” neurons revealed by single-neuron electroporation2015
- Author(s)
  Kei Oyama, Yukina Tateyama, Cheuk Wa Christopher Lo, Shinya Ohara, Fuyuki Karube, Fumino Fujiyama, Toshio Iijima, Ken-Ichiro Tsutsui
- Organizer
  Neuroscience 2015
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16569

1. MIYAKAWA Naohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. NAGAI Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 堀祐樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 筒井健一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OYAMA KEI 小山 佳

Oyama Kei 小山 佳

小山 佳 オヤマ ケイ

Research Projects

Research Products

Co-Researchers

Roles of reciprocal circuits connecting the cortex and thalamus for adaptive behaviorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemogenetic dissection of the primate prefronto-subcortical pathways for adaptive behaviorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemogenetic dissection of the primate prefronto-subcortical pathwaysPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemogenetic dissection of the primate prefronto-subcortical pathways for adaptive behaviorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of the basal ganglia in action selection revealed by single-neuron electrophysiological and histological investigationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規な単一ニューロンの活動記録・染色法を用いた大脳基底核機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Multimodal imaging for validation and optimization of ion channel-based chemogenetics in nonhuman primates2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemogenetic attenuation of cortical seizures in nonhuman primates2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic Behavioral Manipulation via Orally Delivered Chemogenetic Actuator in Macaques2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemogenetic dissection of the primate prefronto-subcortical pathways for working memory and decision-making2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action2019

Author(s)

OYAMA KEI 小山佳

Oyama Kei 小山佳

小山佳オヤマケイ