Hashimoto Yoshitami 橋本吉民

… Alternative Names

橋本吉民ハシモトヨシタミ

HASHIMOTO Yoshitami 橋本吉民

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Researcher Number	50616761
Other IDs	https://orcid.org/0000-0002-8496-7846
Affiliation (Current)	2026: 東京薬科大学, 生命科学部, 助教
Affiliation (based on the past Project Information) *help	2024: 東京薬科大学, 生命科学部, 助教 2019 – 2021: 東京薬科大学, 生命科学部, 助教 2012 – 2017: 東京薬科大学, 生命科学部, 助教
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 43010:Molecular biology-related / Basic Section 43050:Genome biology-related / Biological Sciences Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator アフリカツメガエル卵無細胞系 / レプリソーム / DNA複製フォーク / CDK / 複製フォーク / GINS / Mre11 / Cdc45 / 細胞周期 / Mre11ヌクレアーゼ … More / 複製再開 / アフリカツメガエル卵抽出液 / 複製ストレス / CMGヘリカーゼ / ATR/ATM / AlphaFold3 / CMG複合体 / DNA複製開始 / 小頭症 / DONSON / ユビキチン化制御 / ゲノム安定性 / CDKキナーゼ / Wee1/Myt1 / 核膜崩壊 / Wee1/Myt1キナーゼ / サイクリン依存性キナーゼ / ツメガエル卵無細胞系 / ゲノム不安定化 / 細胞分裂 / DNA複製 / PLK1 / 複製チェックポイント / ユビキチン / p97/VCP / ユビキチン化 / 無細胞複製系 / DNA鎖間架橋 / オーキシンデグロン法 / DNA損傷 / ニワトリDT40細胞 / 組換え修復 / ATM/ATR / Rad51 / リン酸化 / 組換え … More Except Principal Investigator 神経変性疾患 / レジオネラ / syntaxin17 / ミトコンドリア / 小胞体 Less

Studying the role of DONSON in the initiation of eukaryotic DNA replicationPrincipal Investigator
- Principal Investigator
  
  橋本吉民
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Studying the molecular mechanism of replisome disassembly in mitosisPrincipal Investigator
- Principal Investigator
  
  Hashimoto Yoshitami
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
The Regulation of Replisome Dynamics during Replication Fork CollapsePrincipal Investigator
- Principal Investigator
  
  Hashimoto Yoshitami
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo University of Pharmacy and Life Science
一方向からDNA鎖間架橋と衝突した複製フォークのプロセシング機構の解析Principal Investigator
- Principal Investigator
  
  橋本吉民
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Roles of syntaxin 17 in the formation and function of the mitochondria-associated ER membrane
- Principal Investigator
  
  TAGAYA MITSUO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Analyzing the mechanism of recombination-dependent replication restart in eukaryotesPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Yoshitami
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2024 2022 2021 2019 2017 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] 小頭症原因遺伝子DONSONとDNA複製2024
- Author(s)
  橋本吉民
- Journal Title
  
  Medical Science Digest
  
  Volume: 50 Pages: 56-58
- Data Source
  KAKENHI-PROJECT-24K09331
[Journal Article] Mechanism of DNA replication initiation in higher eukaryote2024
- Author(s)
  橋本吉民
- Journal Title
  
  生化学
  
  Volume: 96 Issue: 6 Pages: 859-863
- DOI
  10.14952/SEIKAGAKU.2024.960859
- ISSN
  0037-1017
- Year and Date
  2024-12-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-24K09331
[Journal Article] Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress2022
- Author(s)
  Hashimoto Yoshitami、Tanaka Hirofumi
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 6 Pages: e202101249-e202101249
- DOI
  10.26508/lsa.202101249
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06617
[Journal Article] Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry2021
- Author(s)
  Hashimoto Yoshitami、Tanaka Hirofumi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100033-100033
- DOI
  10.1074/jbc.ra120.015142
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06617
[Presentation] DNA複製開始因子DONSONのCDKリン酸化による制御2024
- Author(s)
  橋本吉民
- Organizer
  第47回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-24K09331
[Presentation] 分裂期レプリソーム脱離機構の解析2019
- Author(s)
  橋本吉民
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06617
[Presentation] Mitotic Replisome Disassembly Is Mediated By p97-dependent and -independent Mechanisims2019
- Author(s)
  Yoshitami Hashimoto
- Organizer
  Eukaryotic DNA Replication & Genome Maintenace
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06617
[Presentation] 分裂期誘導によるレプリソーム解離機構のin vitro解析2017
- Author(s)
  橋本吉民
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-15K06955
[Presentation] Replisome disassembly during replication fork stalling2016
- Author(s)
  橋本吉民
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06955
[Presentation] 停止した複製フォークからのレプリソーム解離機構の解析2015
- Author(s)
  橋本吉民
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06955
[Presentation] 一方向からDNA鎖間架橋と衝突した複製フォークのプロセシング機構の解析2013
- Author(s)
  橋本吉民
- Organizer
  新学術領域研究「ゲノム普遍的制御」第4回領域会議
- Place of Presentation
  鳴門
- Data Source
  KAKENHI-PUBLICLY-25131719
[Presentation] DNA複製ストレス応答におけるPsf2リン酸化の機能解析2013
- Author(s)
  橋本吉民
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-25131719
[Presentation] DNA複製ストレス応答におけるPsf2リン酸化の機能解析2013
- Author(s)
  橋本吉民
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24770170
[Presentation] 複製フォークの停止・再開におけるレプリソーム動態制御
- Author(s)
  橋本吉民、田中弘文
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24770170
[Presentation] 複製フォークの停止・再開おけるレプリソーム動態制御
- Author(s)
  橋本吉民、田中弘文
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25131719

1. TAGAYA MITSUO (30179569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. INOUE Hiroki (10294448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ARASAKI Kohei (70609990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hashimoto Yoshitami 橋本 吉民

橋本 吉民 ハシモト ヨシタミ

HASHIMOTO Yoshitami 橋本 吉民

Research Projects

Research Products

Co-Researchers

Studying the role of DONSON in the initiation of eukaryotic DNA replicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studying the molecular mechanism of replisome disassembly in mitosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Regulation of Replisome Dynamics during Replication Fork CollapsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

一方向からDNA鎖間架橋と衝突した複製フォークのプロセシング機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of syntaxin 17 in the formation and function of the mitochondria-associated ER membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyzing the mechanism of recombination-dependent replication restart in eukaryotesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 小頭症原因遺伝子DONSONとDNA複製2024

Author(s)

Journal Title

Data Source

[Journal Article] Mechanism of DNA replication initiation in higher eukaryote2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] DNA複製開始因子DONSONのCDKリン酸化による制御2024

Author(s)

Organizer

Data Source

[Presentation] 分裂期レプリソーム脱離機構の解析2019

Author(s)

Organizer

Data Source

[Presentation] Mitotic Replisome Disassembly Is Mediated By p97-dependent and -independent Mechanisims2019

Author(s)

Organizer

Data Source

[Presentation] 分裂期誘導によるレプリソーム解離機構のin vitro解析2017

Author(s)

Organizer

Data Source

Hashimoto Yoshitami 橋本吉民

橋本吉民ハシモトヨシタミ

HASHIMOTO Yoshitami 橋本吉民