Takashima Yasuo 高島康郎

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TAKASHIMA Yasuo 高島康郎

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Researcher Number	50621083
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都府立医科大学, 医学部, 研究員 2021: 京都府立医科大学, 医学(系)研究科(研究院), 研究員 2020: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授 2017 – 2019: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2015 – 2016: 九州大学, 生体防御医学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Pathological medical chemistry Except Principal Investigator Basic Section 56010:Neurosurgery-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Neurosurgery
Keywords	Principal Investigator マイクロRNA / PD-1 / 膠芽腫 / let-7 family / miR-93 / PD-L2 / 悪性脳腫瘍 / 幹細胞調節因子 / 神経膠腫 / 脳リンパ腫 … More / がん幹細胞 / 免疫チェックポイント / 分子標的治療薬 / がん細胞リプログラミング / 多変量解析 / 間葉系幹細胞 / Ｎ型糖鎖 / メタボローム解析 / 網羅的N型糖鎖発現解析 / マイクロRNAアレイ / エクソーム解析 / グリオーマ幹細胞 / がん免疫 / メタボローム / トランスクリプトーム / エクソーム / 中枢神経系原発リンパ腫 / 遠隔転移 / ヒト肝細胞癌 / 3Dイメージ / 細胆管反応 / 障害肝モデルマウス / miRNA / LIN28B / 肝前駆細胞 / アポトーシス / Kupffer細胞 / Notchシグナル / 分化転換 / 肝内胆管癌 … More Except Principal Investigator 分子標的 / 薬剤耐性 / メタボローム解析 / 分子標的療法 / ゲノム解析 / 脳リンパ腫 / シングルセル解析 / 自律神経 / ケアプログラム / 自律神経機能 / がん患者 / トランスレーショナルリサーチ / 脳腫瘍 / 脳神経疾患 / 外科 / 臨床 / 癌 / ゲノム / 分子標的薬 / 分子標的創薬 / トランスクリプトーム解析 / 標的分子 / MTX 耐性 / RNA seq 解析 / エクソーム解析 / 分子標的治療 / MTX耐性 / 中枢神経系原発悪性リンパ腫 / 次世代シーケンサー / メタボローム / 免疫療法 / メソトレキセート耐性 / バイオマーカー Less

Development research for molecular-targeted therapy with immune escape-associated microRNAs in malignant brain tumorsPrincipal Investigator
- Principal Investigator
  
  高島康郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of molecular targeted therapy for primary central nervous system lymphomas based on genome and metabolome data.
- Principal Investigator
  
  山中龍也
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of care program based on autonomic function analysis in patients with cancer.
- Principal Investigator
  
  Yamanaka Ryuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Cancer cell reprogramming targeting immune checkpoint in brain tumorsPrincipal Investigator
- Principal Investigator
  
  Takashima Yasuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of molecular targeted therapy for primary central nervous system lymphomas
- Principal Investigator
  
  Yamanaka Ryuya
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyoto Prefectural University of Medicine
Three-dimensional imaging and morphometric analysis on proliferation of pseudo-biliary tracts and differentiation into cholangiocarcinomasPrincipal Investigator
- Principal Investigator
  
  TAKASHIMA Yasuo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University

All 2024 2023 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure2024
- Author(s)
  Sudo Kazuki、Kinoshita Mao、Kawaguchi Ken、Kushimoto Kohsuke、Yoshii Ryogo、Inoue Keita、Yamasaki Masaki、Matsuyama Tasuku、Kooguchi Kunihiko、Takashima Yasuo、Tanaka Masami、Matsumoto Kazumichi、Tashiro Kei、Inaba Tohru、Ohta Bon、Sawa Teiji
- Journal Title
  
  Critical Care
  
  Volume: 28 Issue: 1 Pages: 134-134
- DOI
  10.1186/s13054-024-04921-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08528
[Journal Article] Potential marker subset of blood-circulating cytokines on hematopoietic progenitor-to-Th1 pathway in COVID-192024
- Author(s)
  Takashima Yasuo、Inaba Tohru、Matsuyama Tasuku、Yoshii Kengo、Tanaka Masami、Matsumoto Kazumichi、Sudo Kazuki、Tokuda Yuichi、Omi Natsue、Nakano Masakazu、Nakaya Takaaki、Fujita Naohisa、Sotozono Chie、Sawa Teiji、Tashiro Kei、Ohta Bon
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 11 Pages: 1319980-1319980
- DOI
  10.3389/fmed.2024.1319980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08528, KAKENHI-PROJECT-21K06840, KAKENHI-PROJECT-21H02687, KAKENHI-PROJECT-21H03184
[Journal Article] Reciprocal expression of the immune response genes CXCR3 and IFI44L as module hubs are associated with patient survivals in primary central nervous system lymphoma2023
- Author(s)
  Takashima Y, Hamano M, Yoshii K, Hayano A, Fukai J, Iwadate Y, Kajiwara K, Hondoh H, Yamanaka R.
- Journal Title
  
  Int J Clin Oncol .
  
  Volume: 28(3) Issue: 3 Pages: 468-481
- DOI
  10.1007/s10147-022-02285-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21463
[Journal Article] Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma2021
- Author(s)
  Takashima Yasuo、Kawaguchi Atsushi、Fukai Junya、Iwadate Yasuo、Kajiwara Koji、Hondoh Hiroaki、Yamanaka Ryuya
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 6 Pages: e0251272-e0251272
- DOI
  10.1371/journal.pone.0251272
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-23K21463
[Journal Article] Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma2021
- Author(s)
  Yasuo Takashima, Atsushi Kawaguchi, Junya Fukai, Yasuo Iwadate, Koji Kajiwara, Hiroaki Hondoh, Ryuya Yamanaka
- Journal Title
  
  PLoS One
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001
[Journal Article] 中枢神経系原発悪性リンパ腫における予後予測因子の次世代がん治療再生医療への応用2020
- Author(s)
  高島康郎, 山中龍也
- Journal Title
  
  プレシジョン・メディシン
  
  Volume: 3 Pages: 47-48
- Data Source
  KAKENHI-PROJECT-18K09001
[Journal Article] 中枢神経系原発悪性リンパ腫における予後予測因子の次世代がん治療再生への応用.2020
- Author(s)
  高島康郎,山中龍也
- Journal Title
  
  Precision Medicine
  
  Volume: 3(13) Pages: 1231-1232
- Data Source
  KAKENHI-PROJECT-16H05441
[Journal Article] Metabolome Analysis Reveals Excessive Glycolysis via PI3K/AKT/mTOR and RAS/MAPK Signaling in Methotrexate-Resistant Primary CNS Lymphoma-Derived Cells2020
- Author(s)
  Takashima Y, Hayano A, Yamanaka R
- Journal Title
  
  Clin Cancer Res
  
  Volume: - Pages: 2754-2766
- DOI
  10.1158/1078-0432.ccr-18-3851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441
[Journal Article] 中枢神経系原発悪性リンパ腫のがん細胞ダイレクトリプログラミング候補因子の同定.2020
- Author(s)
  高島康郎,山中龍也
- Journal Title
  
  Medical Science Digest
  
  Volume: 46(8) Pages: 52-53
- Data Source
  KAKENHI-PROJECT-19K22772
[Journal Article] miR-101, miR-548b, miR-554, and miR-1202 are reliable prognosis predictors of the miRNAs associated with cancer immunity in primary central nervous system lymphoma2020
- Author(s)
  Takashima Y, Kawaguchi A, Iwadate Y, Hondoh H, Fukai J, Kajiwara K, Hayano A, Yamanaka R
- Journal Title
  
  PLoS One
  
  Volume: 15(2) Issue: 2 Pages: e0229577-e0229577
- DOI
  10.1371/journal.pone.0229577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441
[Journal Article] 中枢神経系原発悪性リンパ腫のがん細胞ダイレクトリプログラミング候補因子の同定.2020
- Author(s)
  高島康郎,山中龍也
- Journal Title
  
  Medical Science Digest
  
  Volume: 46(8) Pages: 52-53
- Data Source
  KAKENHI-PROJECT-16H05441
[Journal Article] 中枢神経系原発悪性リンパ腫における予後予測因子の次世代がん治療再生への応用.2020
- Author(s)
  高島康郎,山中龍也
- Journal Title
  
  Precision Medicine
  
  Volume: 3(13) Pages: 1231-1232
- Data Source
  KAKENHI-PROJECT-19K22772
[Journal Article] GSEA-assisted gene signatures valid for combinations of prognostic markers in PCNSL2020
- Author(s)
  Takashima Y, Hamano M, Fukai J, Iwadate Y, Kajiwara K, Kobayashi T, Hondoh H, Yamanaka R.
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 8435-8435
- DOI
  10.1038/s41598-020-65463-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-18K09001
[Journal Article] 中枢神経系原発悪性リンパ腫のがん細胞ダイレクトリプログラミング候補因子の同定2020
- Author(s)
  高島康郎, 山中龍也
- Journal Title
  
  メディカル・サイエンス・ダイジェスト
  
  Volume: 46 Pages: 52-53
- Data Source
  KAKENHI-PROJECT-18K09001
[Journal Article] MicroRNA signature constituted of miR-30d, miR-93, and miR-181b is a promising prognostic marker in primary central nervous system lymphoma2019
- Author(s)
  Takashima Yasuo、Kawaguchi Atsushi、Iwadate Yasuo、Hondoh Hiroaki、Fukai Junya、Kajiwara Koji、Hayano Azusa、Yamanaka Ryuya
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 1 Pages: e0210400-e0210400
- DOI
  10.1371/journal.pone.0210400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441
[Journal Article] Promising Prognosis Marker Candidates on the Status of Epithelial-Mesenchymal Transition and Glioma Stem Cells in Glioblastoma2019
- Author(s)
  Takashima Y, Kawaguchi A, Yamanaka R
- Journal Title
  
  Cells
  
  Volume: 8(11) Issue: 11 Pages: 1312-1312
- DOI
  10.3390/cells8111312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441
[Journal Article] Differential expression of N-linked oligosaccharides in methotrexate-resistant primary central nervous system lymphoma cells2019
- Author(s)
  Takashima Y, Yoshimura T, Kano Y, Hayano A, Hondoh H, Ikenaka K, Yamanaka R
- Journal Title
  
  BMC Cancer
  
  Volume: 19(1) Issue: 1 Pages: 910-910
- DOI
  10.1186/s12885-019-6129-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441
[Journal Article] Differential expression of individual transcript variants of PD-1 and PD-L2 genes on Th-1/Th-2 status is guaranteed for prognosis prediction in PCNSL2019
- Author(s)
  Takashima Y, Kawaguchi A, Sato R, Yoshida K, Hayano A, Homma J, Fukai J, Iwadate Y, Kajiwara K, Ishizawa S, Hondoh H, Nakano M, Ogawa S, Tashiro K, Yamanaka R
- Journal Title
  
  Sci Rep
  
  Volume: 9(1) Issue: 1 Pages: 10004-10004
- DOI
  10.1038/s41598-019-46473-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-19K22772, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-17H04046
[Journal Article] Cell-type specific sensitivity of bortezomib in the methotrexate-resistant primary central nervous system lymphoma cells2019
- Author(s)
  Hayano Azusa、Takashima Yasuo、Yamanaka Ryuya
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: April Issue: 9 Pages: 1020-1029
- DOI
  10.1007/s10147-019-01451-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-19K22772
[Journal Article] CD276 and the gene signature composed of GATA3 and LGALS3 enable prognosis prediction of glioblastoma multiforme2019
- Author(s)
  Takashima Yasuo、Kawaguchi Atsushi、Hayano Azusa、Yamanaka Ryuya
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 5 Pages: e0216825-e0216825
- DOI
  10.1371/journal.pone.0216825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-19K22772, KAKENHI-PROJECT-16H05441
[Journal Article] The expression of PD-1 ligands and IDO1 by macrophages/microglia in primary central nervous system lymphoma.2018
- Author(s)
  Miyasato Y, Takashima Y, Takeya H, Yano H, Hayano A, Nakagawa T, Makino K, Takeya M, Yamanaka R, Komohara Y.
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: in press
- NAID
  130007403913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05441
[Journal Article] The expression of PD-1 ligands and IDO1 by macrophage/microglia in primary central nervous system lymphoma2018
- Author(s)
  Miyasato Yuko、Takashima Yasuo、Takeya Hiroto、Yano Hiromu、Hayano Azusa、Nakagawa Takenobu、Makino Keishi、Takeya Motohiro、Yamanaka Ryuya、Komohara Yoshihiro
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 58 Issue: 2 Pages: 95-101
- DOI
  10.3960/jslrt.18001
- NAID
  130007403913
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16K15248
[Journal Article] Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors2018
- Author(s)
  Takashima Yasuo、Horisawa Kenichi、Udono Miyako、Ohkawa Yasuyuki、Suzuki Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 11 Pages: 3543-3553
- DOI
  10.1111/cas.13798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-17K19603, KAKENHI-PROJECT-18K18369, KAKENHI-PUBLICLY-18H04802, KAKENHI-PROJECT-16H01850, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-16K08592, KAKENHI-PROJECT-17K19356, KAKENHI-PUBLICLY-18H05102
[Journal Article] Correlation between lower balance of Th2 helper T-cells and expression of PD-L1/PD-1 axis genes enables prognostic prediction in patients with glioblastoma2018
- Author(s)
  Takashima Yasuo、Kawaguchi Atsushi、Kanayama Tomohiko、Hayano Azusa、Yamanaka Ryuya
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 27 Pages: 19065-19078
- DOI
  10.18632/oncotarget.24897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16K15903
[Journal Article] Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma2018
- Author(s)
  Takashima Yasuo、Sasaki Yasushi、Hayano Azusa、Homma Jumpei、Fukai Junya、Iwadate Yasuo、Kajiwara Koji、Ishizawa Shin、Hondoh Hiroaki、Tokino Takashi、Yamanaka Ryuya
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 44 Pages: 27471-27486
- DOI
  10.18632/oncotarget.25463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16H06279
[Journal Article] Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma.2018
- Author(s)
  Takashima Y, Sasaki Y, Hayano A, Homma J, Fukai J, Iwadate Y, Kajiwara K, Ishizawa S, Hondoh H, Tokino T and Yamanaka R.
- Journal Title
  
  Oncotarget
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05441
[Journal Article] Programmed Cell Death Ligand 1 Expression in Primary Central Nervous System Lymphomas: A Clinicopathological Study.2017
- Author(s)
  Hayano A, Komohara Y, Takashima Y, Takeya H, Homma J, Fukai J, Iwadate Y, Kajiwara K, Ishizawa S, Hondoh H and Yamanaka R.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Pages: 5655-5666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05441
[Journal Article] Trilateral retinoblastoma: A systematic review of 211 cases2017
- Author(s)
  Yamanaka Ryuya、Hayano Azusa、Takashima Yasuo
- Journal Title
  
  Neurosurgical Review
  
  Volume: － Issue: 1 Pages: 39-48
- DOI
  10.1007/s10143-017-0890-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K15903
[Journal Article] Secondary Intracranial Tumors Following Radiotherapy for Pituitary Adenomas: A Systematic Review2017
- Author(s)
  Yamanaka Ryuya、Abe Eisuke、Sato Toshiteru、Hayano Azusa、Takashima Yasuo
- Journal Title
  
  Cancers
  
  Volume: 9 Issue: 8 Pages: 103-103
- DOI
  10.3390/cancers9080103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K15903
[Journal Article] Suppression of let-7b and miR-125a/b maturation by Lin28b enables maintenance of stem cell properties in hepatoblasts2016
- Author(s)
  Takashima Y, Terada M, Udono M, Miura S, Yamamoto J, Suzuki A
- Journal Title
  
  Hepatology
  
  Volume: in press Issue: 1 Pages: 245-260
- DOI
  10.1002/hep.28548
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19025, KAKENHI-PLANNED-23112002, KAKENHI-PROJECT-25713014, KAKENHI-PROJECT-16H01850, KAKENHI-PROJECT-16J02459
[Journal Article] Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma2016
- Author(s)
  Terada M., Horisawa K., Miura S., Takashima Y., Ohkawa Y., Sekiya S., Matsuda-Ito K., Suzuki A.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34691-34691
- DOI
  10.1038/srep34691
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01850, KAKENHI-PROJECT-16J02459, KAKENHI-PROJECT-25713014, KAKENHI-PROJECT-15K19025, KAKENHI-PROJECT-16K08592
[Presentation] 中枢神経系原発悪性リンパ腫におけるがんの形態及び微小環境に関連する遺伝子の発現パターンによる予後予測2021
- Author(s)
  高島康郎, 川口淳,深井順也, 岩立康男, 梶原浩司,本道洋昭, 山中龍也
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K21463
[Presentation] 中枢神経系原発悪性リンパ腫におけるがんの形態及び微小環境に関連する遺伝子の発現パターンによる予後予測2021
- Author(s)
  高島康郎, 川口淳,深井順也, 岩立康男, 梶原浩司,本道洋昭, 山中龍也.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22772
[Presentation] 中枢神経系原発悪性リンパ腫におけるがん免疫マイクロRNAによる予後予測.2021
- Author(s)
  高島康郎, 川口淳, 岩立康男, 本道洋昭,深井順也, 梶原浩司, 早野あづさ, 山中龍也.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22772
[Presentation] 中枢神経系原発悪性リンパ腫におけるがん免疫マイクロRNAによる予後予測.2021
- Author(s)
  高島康郎, 川口淳, 岩立康男, 本道洋昭,深井順也, 梶原浩司, 早野あづさ, 山中龍也
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21463
[Presentation] メトトレキサート耐性原発性中枢神経系リンパ腫におけるmTORおよび低酸素シグナル伝達経路による解糖系の亢進.2020
- Author(s)
  高島康郎,早野あづさ,山中龍也.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22772
[Presentation] メトトレキサート耐性原発性中枢神経系リンパ腫におけるmTORおよび低酸素シグナル伝達経路による解糖系の亢進.2020
- Author(s)
  高島康郎,早野あづさ,山中龍也.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] 膠芽腫における上皮間葉転換およびグリオーマ幹細胞に関する遺伝子発現による予後予測.2020
- Author(s)
  高島康郎,川口淳,山中龍也.
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] Excessive glycolysis with mTOR and hypoxia signaling pathways in methotrexate-resistant primary CNS lymphoma cells2020
- Author(s)
  Yasuo Takashima, Azusa Hayano, Ryuya Yamanaka
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] 膠芽腫における上皮間葉転換およびグリオーマ幹細胞に関する遺伝子発現による予後予測.2020
- Author(s)
  高島康郎,川口淳,山中龍也.
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22772
[Presentation] 膠芽腫における上皮間葉転換およびグリオーマ幹細胞に関する遺伝子発現による予後予測2020
- Author(s)
  高島康郎, 川口淳, 山中龍也
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] The miRNA signature constituted of miR-30d, miR-93, and miR-181b as promising prognostic markers in primary CNS lymphoma.2019
- Author(s)
  Takashima Y, Kawaguchi A, Iwadate Y, Hondoh H, Fukai J, Kajiwara K, Hayano A, Yamanaka R
- Organizer
  第78回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22772
[Presentation] The miRNA signature constituted of miR-30d, miR-93, and miR-181b as promising prognostic markers in primary CNS lymphoma2019
- Author(s)
  Yasuo Takashima, Atsushi Kawaguchi, Yasuo Iwadate, Hiroaki Hondoh, Junya Fukai, Koji Kajiwara, Azusa Hayano, Ryuya Yamanaka
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] 中枢神経系原発悪性リンパ腫におけるTh1/Th2バランスとPD-1およびPD-L2遺伝子発現による予後予測.2019
- Author(s)
  高島康郎, 川口淳, 佐藤隆一, 吉田健一, 早野あづさ, 本間順平, 深井順也, 岩立康男, 梶原浩司, 石澤伸, 本道洋昭, 中野正和, 小川誠司, 田代啓, 山中龍也.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22772
[Presentation] 中枢神経系原発悪性リンパ腫におけるTh1/Th2バランスとPD-1およびPD-L2遺伝子発現による予後予測2019
- Author(s)
  高島康郎、川口淳、佐藤隆一、吉田健一、早野あづさ、本間順平、深井順也、岩立康男、梶原浩司、石澤伸、本道洋昭、中野正和、小川誠司、田代啓、山中龍也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] 中枢神経系原発悪性リンパ腫におけるTh1/Th2バランスとPD-1およびPD-L2遺伝子発現による予後予測.2019
- Author(s)
  高島康郎, 川口淳, 佐藤隆一, 吉田健一, 早野あづさ, 本間順平, 深井順也, 岩立康男, 梶原浩司, 石澤伸, 本道洋昭, 中野正和, 小川誠司, 田代啓, 山中龍也.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] The miRNA signature constituted of miR-30d, miR-93, and miR-181b as promising prognostic markers in primary CNS lymphoma2019
- Author(s)
  Takashima Y, Kawaguchi A, Iwadate Y, Hondoh H, Fukai J, Kajiwara K, Hayano A, Yamanaka R
- Organizer
  第78回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] Expression analysis of N-oligosaccharides of glycoproteins in methotrexate-resistant central nervous system lymphoma cell lines2018
- Author(s)
  Yasuo Takashima, Takeshi Yoshimura, Yuichiro Kano, Azusa Hayano, Hiroaki Hondoh, Kazuhiro Ikenaka, Ryuya Yamanaka
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] メソトレキセート耐性中枢神経系原発悪性リンパ腫細胞株におけるN型糖鎖の発現解析.2018
- Author(s)
  高島康郎、吉村武、加納雄一朗、早野あづさ、本道洋昭、池中一裕、山中龍也.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] 中枢神経系原発悪性リンパ腫におけるIon Reporterエクソームシーケンシングによる分子マーカー候補の同定.2018
- Author(s)
  高島康郎、佐々木泰史、早野あづさ、本間順平、深井順也、岩立康男、梶原浩司、石澤伸、本道洋昭、時野隆至、山中龍也
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] Identification of molecular marker candidate by Ion Reporter exome sequencing in primary central nervous system lymphoma2018
- Author(s)
  Yasuo Takashima, Yasushi Sasaki, Azusa Hayano, Jumpei Homma, Junya Fukai, Yasuo Iwadate, Koji Kajiwara, Shin Ishizawa, Hiroaki Hondoh, Takashi Tokino, Ryuya Yamanaka
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] Establishment of methotrexate-resistant primary central nervous system lymphoma cell lines and sensitivity to bortezomib2018
- Author(s)
  Azusa Hayano, Yasuo Takashima and Ryuya Yamanaka
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09001
[Presentation] メトトレキサート耐性中枢神経原発悪性リンパ腫細胞株の樹立およびボルテゾミブ感受性の検討.2018
- Author(s)
  早野あづさ、高島康郎、山中龍也.
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] がん免疫療法のターゲットとなる分子と予後との関連の解析.2017
- Author(s)
  高島康郎、川口淳、金山知彦、早野あづさ、山中龍也.
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] 脳原発および転移性脳悪性リンパ腫におけるProgrammed Cell Death Ligand 1発現の検討.2017
- Author(s)
  早野あづさ、菰原義宏、高島康郎、本間順平、深井順也、岩立康男、梶原浩司、石澤伸、本道洋昭、山中龍也.
- Organizer
  第76回日本癌学会学術集会,
- Data Source
  KAKENHI-PROJECT-16H05441
[Presentation] 肝内胆管がんモデルマウスにおいて、クッパー細胞がNotchシグナルを活性化し、肝細胞の分化転換を誘導する2016
- Author(s)
  寺田茉衣子, 堀澤健一, 三浦静, 高島康郎, 大川恭行, 関谷明香, 松田花菜江, 鈴木淳史
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K19025

1. Yamanaka Ryuya (20323991)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
2. 川口淳 (60389319)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
3. 池中一裕 (00144527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 吉田健一 (50738226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 早野あづさ (10379018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. 金山知彦 (40401187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 田村沙織 (50756210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐々木泰史 (70322328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 深井順也 (50543774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 岩立康男 (70272309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 田代啓 (10263097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. Horisawa Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. Ohkawa Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. Miura Shizuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 鈴木淳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 時野隆至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takashima Yasuo 高島 康郎

TAKASHIMA Yasuo 高島 康郎

Research Projects

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Co-Researchers

Development research for molecular-targeted therapy with immune escape-associated microRNAs in malignant brain tumorsPrincipal Investigator

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Development of molecular targeted therapy for primary central nervous system lymphomas based on genome and metabolome data.

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Development of care program based on autonomic function analysis in patients with cancer.

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Cancer cell reprogramming targeting immune checkpoint in brain tumorsPrincipal Investigator

Principal Investigator

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Development of molecular targeted therapy for primary central nervous system lymphomas

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Three-dimensional imaging and morphometric analysis on proliferation of pseudo-biliary tracts and differentiation into cholangiocarcinomasPrincipal Investigator

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[Journal Article] Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure2024

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[Journal Article] Potential marker subset of blood-circulating cytokines on hematopoietic progenitor-to-Th1 pathway in COVID-192024

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[Journal Article] Reciprocal expression of the immune response genes CXCR3 and IFI44L as module hubs are associated with patient survivals in primary central nervous system lymphoma2023

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[Journal Article] Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma2021

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[Journal Article] Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma2021

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[Journal Article] 中枢神経系原発悪性リンパ腫における予後予測因子の次世代がん治療再生医療への応用2020

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[Journal Article] 中枢神経系原発悪性リンパ腫における予後予測因子の次世代がん治療再生への応用.2020

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[Journal Article] Metabolome Analysis Reveals Excessive Glycolysis via PI3K/AKT/mTOR and RAS/MAPK Signaling in Methotrexate-Resistant Primary CNS Lymphoma-Derived Cells2020

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[Journal Article] 中枢神経系原発悪性リンパ腫のがん細胞ダイレクトリプログラミング候補因子の同定.2020

Author(s)

Takashima Yasuo 高島康郎

TAKASHIMA Yasuo 高島康郎