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Kawamori Dan  河盛 段

ORCIDConnect your ORCID iD *help
Researcher Number 50622362
Other IDs
Affiliation (Current) 2025: 大阪大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help 2020 – 2023: 大阪大学, 医学部附属病院, 准教授
2016 – 2020: 大阪大学, 医学系研究科, 助教
2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 54040:Metabolism and endocrinology-related / Metabolomics
Except Principal Investigator
Basic Section 54040:Metabolism and endocrinology-related / Metabolomics
Keywords
Principal Investigator
グルカゴン / 糖尿病 / インクレチン / 膵α細胞 / DPP-4 / GLP-1 / ストレス応答 / 多様性 / インスリンシグナル / シグナル伝達 / 代謝異常 / エネルギー代謝 … More
Except Principal Investigator
… More 膵β細胞 / 分化転換 / インスリン転写因子 / 膵β細胞再生 / 転写因子 / 分化誘導 / 膵β細胞化 / インスリン転写因子 / インスリン分泌 / 膵β細胞糖毒性 / 膵β細胞障害 / 高血糖毒性 / 糖尿病 Less
  • Research Projects

    (5 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (3 People)
  •  Pathophysiological analysis of pancreatic alpha cell function targeting DPP-4 expression for future development of therapeutic strategies for diabetesPrincipal Investigator

    • Principal Investigator
      Kawamori Dan
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Osaka University
  •  Pathophysiological analyses of functional subtypes in pancreatic alpha-cellsPrincipal Investigator

    • Principal Investigator
      Kawamori Dan
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Osaka University
  •  A trial for efficient transdifferentiation toward pancreatic beta cells

    • Principal Investigator
      Matsuoka Takaaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Wakayama Medical University
      Osaka University
  •  Functional recovery of daibetic beta cells and the attempt for generating functional beta cells

    • Principal Investigator
      Matsuoka Takaaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  Pathophysiological analyses of glucagon dysregulation in development of glucose intolerance and diabetes.Principal Investigator

    • Principal Investigator
      Kawamori Dan
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] 糖尿病治療UPDATE2024「糖尿病治療薬・基礎研究・臨床評価が拓く、グルカゴンの重要性解明」2024

    • Author(s)
      河盛 段、河盛隆造
    • Journal Title

      CLINIC magazine

      Volume: 51 Pages: 26-36

    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Journal Article] 座談会 糖尿病病態研究と診療の未来2024

    • Author(s)
      大杉 満、田村好史、河盛 段
    • Journal Title

      Current Therapy

      Volume: 42 Pages: 164-169

    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Journal Article] Different post-pancreatectomy glucagon responses to a meal test between surgical approaches2023

    • Author(s)
      Matsuda Tsuguka、Himeno Natsumi、Nakashima Akira、Nakagawa Naoya、Kohashi Toshihiko、Kawamori Dan、Kamei Nozomu
    • Journal Title

      Endocr J

      Volume: 70 Issue: 11 Pages: 1077-1085

    • DOI

      10.1507/endocrj.EJ23-0032

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Journal Article] Characteristic changes in plasma glutamate levels and free amino acid profiles in Japanese patients with type 1 diabetes mellitus2023

    • Author(s)
      Kawamori Dan、Kageyama Yoko、Tanaka Takayuki、Ishizaka Yuko、Hosoe Shigero、Katakami Naoto、Shimomura Iichiro
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 14 Issue: 1 Pages: 111-121

    • DOI

      10.1111/jdi.13911

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Journal Article] Change in pharmacodynamic variables following once‐weekly tirzepatide treatment versus dulaglutide in Japanese patients with type 2 diabetes (SURPASS J‐mono substudy)2023

    • Author(s)
      Yabe Daisuke、Kawamori Dan、Seino Yusuke、Oura Tomonori、Takeuchi Masakazu
    • Journal Title

      Diabetes, Obesity and Metabolism

      Volume: 25 Issue: 2 Pages: 398-406

    • DOI

      10.1111/dom.14882

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08576, KAKENHI-PROJECT-21K11608, KAKENHI-PROJECT-21K19504
  • [Journal Article] Newly discovered knowledge pertaining to glucagon and its clinical applications2023

    • Author(s)
      Kawamori D, Sasaki S
    • Journal Title

      J Diabetes Investig

      Volume: Online ahead of print Issue: 7 Pages: 829-837

    • DOI

      10.1111/jdi.14009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16395, KAKENHI-PROJECT-21K20902, KAKENHI-PROJECT-21K08576
  • [Journal Article] 特集「生理活性ペプチド」各論5「グルカゴンに関する新知見と臨床応用」2022

    • Author(s)
      河盛 段
    • Journal Title

      BIO Clinica

      Volume: 37 Pages: 336-40

    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Journal Article] Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling2022

    • Author(s)
      Okita Tomonori、Kita Shunbun、Fukuda Shiro、Fukuoka Keita、Kawada-Horitani Emi、Iioka Masahito、Nakamura Yuto、Fujishima Yuya、Nishizawa Hitoshi、Kawamori Dan、Matsuoka Taka-aki、Norikazu Maeda、Shimomura Iichiro
    • Journal Title

      iScience

      Volume: 25 Issue: 11 Pages: 105404-105404

    • DOI

      10.1016/j.isci.2022.105404

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08576, KAKENHI-PROJECT-22K08669, KAKENHI-PROJECT-21K16340, KAKENHI-PROJECT-21K16353, KAKENHI-PROJECT-20K20606
  • [Journal Article] 糖尿病における膵α細胞機能条の実態は?“bi-hormonal disorder”から“bi-directional disorder”へ&2021

    • Author(s)
      河盛 段、細江重郎
    • Journal Title

      月刊糖尿病

      Volume: 131 Pages: 45-51

    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Journal Article] Plasma lipopolysaccharide binding protein level statistically mediates between body mass index and chronic microinflammation in Japanese patients with type 1 diabetes.2020

    • Author(s)
      Watanabe H, Katsura T, Takahara M, Miyashita K, Katakami N, Matsuoka TA, Kawamori D, Shimomura I
    • Journal Title

      Diabetology International

      Volume: na Issue: 3 Pages: 293-297

    • DOI

      10.1007/s13340-020-00428-8

    • NAID

      40022307419

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Journal Article] Beginning of a new era in glucagon research: Breakthrough by the new glucagon assay2020

    • Author(s)
      Kawamori Dan
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 11 Issue: 5 Pages: 1123-1125

    • DOI

      10.1111/jdi.13275

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Journal Article] Consistency of plasma glucagon levels in patients with type 1 diabetes after a one-year period.2020

    • Author(s)
      Kawamori D, Katakami N, Takahara M, Miyashita K, Takebe S, Yasuda T, Matsuoka TA, Shimomura I
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 11 Issue: 2 Pages: 337-340

    • DOI

      10.1111/jdi.13134

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Journal Article] Alpha the versatile: Guardians of the islets2019

    • Author(s)
      Kawamori Dan
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 10 Issue: 1 Pages: 26-28

    • DOI

      10.1111/jdi.12875

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Journal Article] Dysregulated plasma glucagon levels in Japanese young adult type 1 diabetes patients2019

    • Author(s)
      Kawamori Dan、Katakami Naoto、Takahara Mitsuyoshi、Miyashita Kazuyuki、Sakamoto Fumie、Yasuda Tetsuyuki、Matsuoka Taka-aki、Shimomura Iichiro
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 10 Issue: 1 Pages: 62-66

    • DOI

      10.1111/jdi.12862

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Journal Article] Glucotoxicity induces abnormal glucagon secretion through impaired insulin signaling in InR1G cells.2017

    • Author(s)
      Takashi Katsura, Dan Kawamori, Eri Aida, Taka-aki Matsuoka, Iichiro Shimomura
    • Journal Title

      PLOS ONE

      Volume: 印刷中 Issue: 4 Pages: e0176271-e0176271

    • DOI

      10.1371/journal.pone.0176271

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Journal Article] Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells into β-Cells in Vivo2017

    • Author(s)
      Matsuoka TA, Kawashima S, Miyatsuka T, Sasaki S, Shimo N, Katakami N, Kawamori D, Takebe S, Herrera PL, Kaneto H, Stein R, Shimomura I
    • Journal Title

      Diabetes

      Volume: 66 Issue: 5 Pages: 1293-1300

    • DOI

      10.2337/db16-0887

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09388
  • [Journal Article] インスリンがグルカゴンに作用する!α細胞とインスリンシグナル2015

    • Author(s)
      河盛 段
    • Journal Title

      実験医学

      Volume: 33 Pages: 880-886

    • Data Source
      KAKENHI-PROJECT-26461336
  • [Journal Article] α細胞機能調節機構2015

    • Author(s)
      河盛 段、桂 央士
    • Journal Title

      ホルモンと臨床

      Volume: 62 Pages: 65-72

    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] シンポジウム「臨床・基礎におけるグルカゴン研究の進歩 / Recent progress in glucagon research: clinical and basic」グルカゴン分泌異常機序の解明とその臨床的検証 / Exploring the molecular mechanisms underlying abnormal glucagon secretion and its verification: research from basic to clinical2022

    • Author(s)
      河盛 段
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08576
  • [Presentation] グルカゴン研究Update20212021

    • Author(s)
      河盛 段
    • Organizer
      第55回糖尿病学の進歩
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] グルカゴンの評価からみえるエネルギーの流れ2020

    • Author(s)
      河盛 段
    • Organizer
      第54回糖尿病学の進歩
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] 成人1型糖尿病患者は血中アミノ酸プロファイルの変化を呈する2020

    • Author(s)
      河盛 段、影山陽子、田中孝幸、片上直人、宮下和幸、武部里美、松岡孝昭、下村伊一郎
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] シンポジウム「グルカゴン・インクレチン研究Up to date」糖尿病における膵α細胞機能異常とグルカゴン臨床評価2020

    • Author(s)
      河盛 段
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] 成人1型糖尿病患者健診における血中グルカゴン値の年次変化2019

    • Author(s)
      河盛 段、片上直人、髙原充佳、宮下和幸、坂本扶美枝、武部里美、安田哲行、松岡孝昭、下村伊一郎
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] 糖尿病治療薬が再び光を当てたグルカゴンの新しい意義2019

    • Author(s)
      河盛 段
    • Organizer
      第8回くすりと糖尿病学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] Update「肥満、糖尿病1」:糖尿病臨床におけるグルカゴンの新認識2018

    • Author(s)
      河盛 段
    • Organizer
      第28回臨床内分泌代謝Update
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] 成人1型糖尿病患者における血中グルカゴン値の評価2018

    • Author(s)
      河盛 段、片上直人、髙原充佳、宮下和幸、坂本扶美枝、安田哲行、松岡孝昭、下村伊一郎
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] シンポジウム「グルカゴンはどこまで判ったか」:Regulation of α-cell function and fate by intra-islet effect of insulin from β-cells.2018

    • Author(s)
      河盛 段
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08511
  • [Presentation] 高グルコース誘導性グルカゴン分泌異常メカニズムにおけるJNKの寄与2017

    • Author(s)
      桂 央士、河盛 段、高比康充、下 直樹、松岡孝昭、下村伊一郎
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2017-05-18
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] 膵β細胞糖毒性感受性遺伝子の新規同定と解析2017

    • Author(s)
      下直樹、松岡孝昭、河盛段、宮塚健、小山佳久、島田昌一、下村伊一郎
    • Organizer
      第29回 分子糖尿病学シンポジウム
    • Data Source
      KAKENHI-PROJECT-15K09388
  • [Presentation] マウスに対する高蛋白摂取は、負荷早期よりグルカゴン分泌異常と耐糖能異常を誘導する2016

    • Author(s)
      桂 央士、河盛 段、小林雅樹、北村忠弘、松岡孝昭、下村伊一郎
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] 慢性高グルコースによるα細胞グルカゴン分泌異常発症の背景メカニズムの同定。2015

    • Author(s)
      河盛 段、桂 央士、相田絵理、松岡孝昭、下村伊一郎
    • Organizer
      第88回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-04-23
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] グルカゴン分泌制御におけるインスリン作用の意義の探索2015

    • Author(s)
      桂 央士、河盛 段、松岡孝昭、下村伊一郎
    • Organizer
      第27回分子糖尿病学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-12-05
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] 糖尿病慢性高血糖によるグルカゴン調節異常発症の分子メカニズムの解析2015

    • Author(s)
      桂 央士、河盛 段、相田絵里、久保典代、松岡孝昭、下村伊一郎
    • Organizer
      第58回日本糖尿病学会学術集会
    • Place of Presentation
      下関、山口
    • Year and Date
      2015-05-15
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] Chronic high glucose load induces dysregulation of glucagon secretion through impaired insulin signaling.2015

    • Author(s)
      Kawamori D, Katsura T, Aida E, Kaneto H, Matsuoka T, Shimomura I.
    • Organizer
      American Diabetes Association 75th Scientific Sessions
    • Place of Presentation
      Boston, MA, U.S.A.
    • Year and Date
      2015-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] ワークショップ「古くて新しい糖代謝経路研究の最前線」Discovery of new roles for glucagon and pancreatic α-cells。2015

    • Author(s)
      河盛 段
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸、兵庫
    • Year and Date
      2015-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461336
  • [Presentation] Symposium "Glucagon Renaissance in Osaka"; Intraislet regulation of α-cells in glucagon secretion and islet maintenance.2014

    • Author(s)
      Dan Kawamori
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461336
  • 1.  Matsuoka Takaaki (10379258)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 15 results
  • 2.  片上 直人 (10403049)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  佐々木 周伍
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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