SHINAGAWA Kei 品川慶

Researcher Number	50623609
Affiliation (based on the past Project Information) *help	2013: 広島大学, 大学病院, 医科診療医 2012: 広島大学, 大学病院, 病院(医) 医科診療医 2011: 広島大学, 病院, 医科診療医
Review Section/Research Field	Principal Investigator Tumor biology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 大腸癌 / フィブロネクチン / メタロチオネイン / 間葉系幹細胞 Except Principal Investigator Metastasis / Colon cancer / Carcinoma-associated fibroblast (CAF) / Mesenchymal stem cell (MSC) / 大腸癌 / CAF … More / MSC / 分子標的治療 / 癌転移 / 間質 / 骨髄由来間葉系幹細胞 / 下部消化管学(小腸、大腸) Less

The role of metallothionein genes in tumor-promoting effect of bone marrow-derived mesenchymal stem cells in human colon cancerPrincipal Investigator
- Principal Investigator
  
  SHINAGAWA KEI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Hiroshima University
Role of bone-marrow derived mesenchymal stem cells in growth and metastasis of colon cancer.
- Principal Investigator
  
  KITADAI Yasuhiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University

All 2014 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] Enhanced growth and metastasis of colon cancer : Role of mesenchymal stem cells.Stem Cells and Cancer Stem Cells : Therapeutic Applications in Desease and Injury, Volume 4 (Hayat, M.A., ed)2012
- Author(s)
  Kitadai, Y., Shinagawa, K.
- Publisher
  Springer, USA(in press)
- Data Source
  KAKENHI-PROJECT-21590813
[Book] Enhancedgrowth and metastasis of colon cancer : Roleof mesenchymal stem cells. Stem Cells andCancer Stem Cells2012
- Author(s)
  Kitadai, Y., Shinagawa, K
- Publisher
  TherapeuticApplications in Disease and Injury
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer2013
- Author(s)
  Shinagawa K
- Journal Title
  
  Int J Cancer
  
  Volume: 132 Issue: 4 Pages: 813-823
- DOI
  10.1002/ijc.27735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390088, KAKENHI-PROJECT-24700979, KAKENHI-PROJECT-25670762
[Journal Article] Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer.2013
- Author(s)
  Shinagawa Kei
- Journal Title
  
  International Journal of Cancer
  
  Volume: 15 Pages: 813-823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700979
[Journal Article] Stroma-directed molecular targeted therapyin gastric cancer2011
- Author(s)
  Kitadai, Y., Kodama, M., Shinagawa, K.
- Journal Title
  
  Cancers
  
  Volume: 3 Pages: 4245-4057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model2011
- Author(s)
  Sumida, T., Kitadai, Y., Shinagawa, K., Tanaka, M., Kodama, M., Ohnishi, M., Ohara, E., Tanaka, S., Yasui, W., Chayama, K.
- Journal Title
  
  Int J Cancer
  
  Volume: 128 Pages: 2050-2062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Stroma-directed molecular targeted therapy in gastric cancer2011
- Author(s)
  Kitadai, Y., Kodama, M., Shinagawa, K
- Journal Title
  
  Cancers, 3
  
  Volume: 3 Pages: 4245-4257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Mesenchymal stem cells enhance growth and metastasis of colon cancer.2010
- Author(s)
  Shinagawa, K., Kitadai, Y., et al
- Journal Title
  
  Int J Cancer
  
  Volume: 127 Pages: 2323-2333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Mesenchymal stem cells enhance growthand metastasis of colon cancer2010
- Author(s)
  Shinagawa, K., Kitadai, Y., Tanaka, M., Sumida, T., Kodama, M., Higashi, Y., Tanaka, S., Yasui, W., Chayama, K.
- Journal Title
  
  Int J Cancer
  
  Volume: 127 Pages: 2323-2333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Expression of platelet-derivedgrowth factor(PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma2010
- Author(s)
  Kodama, M., Kitadai, Y., Sumida, T., Ohnishi, M., Ohara, E., Tanaka, M., Shinagawa, K., Tanaka, S., Yasui, W., Chayama, K.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 1984-1989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Journal Article] Potential rolefor vascular endothelial growth factor-D asan autocrine factor for human gastric carcinoma cells2010
- Author(s)
  Tanaka, M., Kitadai, Y., Kodama, M., Shinagawa, K. Sumida, T., Tanaka, S., Oue, N., Yasui, W., Chayama, K.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2121-2127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590813
[Presentation] 骨髄由来間葉系幹細胞の大腸癌増殖・転移促進機構についての研究2014
- Author(s)
  品川慶、北台靖彦
- Organizer
  第3回先端がん転移研究討論会
- Place of Presentation
  熱海市
- Year and Date
  2014-02-15
- Data Source
  KAKENHI-PROJECT-24700979
[Presentation] 第3回先端がん転移研究討論会2014
- Author(s)
  品川　慶
- Organizer
  骨髄由来間葉系幹細胞の大腸癌増殖・転移促進機構についての研究
- Place of Presentation
  静岡県熱海市
- Data Source
  KAKENHI-PROJECT-24700979
[Presentation] Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces metallothionein gene expression in human colon cancer2013
- Author(s)
  Shinagawa K, Kitadai Y, Yuge R, Onoyama M, Ohnishi M, Tanaka S, Yasui W, Chayama K
- Organizer
  104th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington, D.C., USA (poster presentation)
- Year and Date
  2013-04-09
- Data Source
  KAKENHI-PROJECT-24700979
[Presentation] Bone marrow-derived mesenchymal stem cells induces metallothionein gene expression in human colon cancer2013
- Author(s)
  Shinagawa K, Kitadai Y, Tanaka Y, Yuge R, Onoyama M, Tanaka S, Yasui W, Chayama K
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  横浜市 (ポスター発表)
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24700979
[Presentation] Bone marrow-derived mesenchymal stem cells induces metallothionein gene expression in human colon cancer.2013
- Author(s)
  Shinagawa Kei
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24700979
[Presentation] Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces metallothionein gene expression in human colon cancer2013
- Author(s)
  Shinagawa Kei
- Organizer
  AACR 104th Annual Meeting 2013
- Place of Presentation
  Washington, D.C., USA
- Data Source
  KAKENHI-PROJECT-24700979
[Presentation] Blockade of PDGFR signaling with imatinib inhibits lymph node metastasis ofgastric carcinoma in an orthotopic nudemouse model2011
- Author(s)
  Kitadai, Y., Kodama, M., Sumida, T., Shinagawa, K., Tanaka, S., Chayama, K.
- Organizer
  Montreal International Symposium on Angiogenesis and Metastasis (MISAM)
- Place of Presentation
  Montreal, Quebec, Canada
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-21590813
[Presentation] Blockade of PDGFR signaling impairs the tumor promoting effect of bone marrow-derived mesenchymal stem cells in colon cancer2011
- Author(s)
  Shinagawa, K., Kitadai, Y., et al
- Organizer
  102st Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Orland, FL, USA
- Data Source
  KAKENHI-PROJECT-21590813
[Presentation] Blockade ofPDGFR signaling impairs the tumorpromoting effect of bone marrow-derivedmesenchymal stem cells in colon cancer2011
- Author(s)
  Shinagawa, K., Kitadai, Y., Ohnishi, M., Ohara, E., Tanaka, M., Sumida, T., Tanaka, S., Yasui, W., Chayama, K.
- Organizer
  102st Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Orland, FL, USA,
- Data Source
  KAKENHI-PROJECT-21590813
[Presentation] Significance of mesenchymal stem cells in growth and metastasis of colon cancer2010
- Author(s)
  Shinagawa, K., Kitadai, Y., Tanaka, M., Sumida, T., Kodama, M., Tanaka, S., Yasui, W., Chayama, K.
- Organizer
  101st Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington D.C., USA
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21590813
[Presentation] Blockade of PDGFRsignaling impairs the tumor promotingeffect of bone marrow-derivedmesenchymal stem cells in colon cancer2010
- Author(s)
  Kitadai, Y., Shinagawa, K., Tanaka, M., Sumida, T., Kodama, M., Tanaka, S., Yasui, W., Chayama, K.
- Organizer
  Joint Metastasis Research Society-AAC Rconference
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-21590813
[Presentation] Significance of mesenchymal stem cells in growth and metastasis of colon cancer.2010
- Author(s)
  Shinagawa, K., Kitadai, Y., et al
- Organizer
  101st Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington D.C., USA
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21590813

1. KITADAI Yasuhiko (10304437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results

SHINAGAWA Kei 品川 慶

Research Projects

Research Products

Co-Researchers

The role of metallothionein genes in tumor-promoting effect of bone marrow-derived mesenchymal stem cells in human colon cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of bone-marrow derived mesenchymal stem cells in growth and metastasis of colon cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Enhanced growth and metastasis of colon cancer : Role of mesenchymal stem cells.Stem Cells and Cancer Stem Cells : Therapeutic Applications in Desease and Injury, Volume 4 (Hayat, M.A., ed)2012

Author(s)

Publisher

Data Source

[Book] Enhancedgrowth and metastasis of colon cancer : Roleof mesenchymal stem cells. Stem Cells andCancer Stem Cells2012

Author(s)

Publisher

Data Source

[Journal Article] Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer.2013

Author(s)

Journal Title

Data Source

[Journal Article] Stroma-directed molecular targeted therapyin gastric cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model2011

Author(s)

Journal Title

Data Source

[Journal Article] Stroma-directed molecular targeted therapy in gastric cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] Mesenchymal stem cells enhance growth and metastasis of colon cancer.2010

Author(s)

Journal Title

Data Source

[Journal Article] Mesenchymal stem cells enhance growthand metastasis of colon cancer2010

Author(s)

Journal Title

Data Source

[Journal Article] Expression of platelet-derivedgrowth factor(PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma2010

Author(s)

Journal Title

Data Source

[Journal Article] Potential rolefor vascular endothelial growth factor-D asan autocrine factor for human gastric carcinoma cells2010

Author(s)

Journal Title

Data Source

[Presentation] 骨髄由来間葉系幹細胞の大腸癌増殖・転移促進機構についての研究2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 第3回先端がん転移研究討論会2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces metallothionein gene expression in human colon cancer2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Bone marrow-derived mesenchymal stem cells induces metallothionein gene expression in human colon cancer2013

Author(s)

SHINAGAWA Kei 品川慶