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Matsumaru Daisuke  松丸 大輔

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MATSUMARU Daisuke  松丸 大輔

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Researcher Number 50624152
Other IDs
Affiliation (Current) 2025: 岐阜薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 岐阜薬科大学, 薬学部, 准教授
2019 – 2022: 岐阜薬科大学, 薬学部, 講師
2017 – 2018: 東北大学, 加齢医学研究所, 助教
2015 – 2016: 和歌山県立医科大学, 先端医学研究所, 助教
2012 – 2014: 和歌山県立医科大学, 先端医学研究所, 学内助教
Review Section/Research Field
Principal Investigator
General medical chemistry / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 48040:Medical biochemistry-related
Except Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 63030:Chemical substance influence on environment-related / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords
Principal Investigator
総排泄腔 / マウス / アンドロゲン / 炎症 / 卵巣 / イメージング / 直腸肛門奇形 / Shh / 肛門直腸奇形 / 遺伝子改変マウス … More / 先天性奇形 / マクロファージ / 多嚢胞性卵巣症候群 / 不妊 / 性ホルモン / 鉄染色 / KEAP1-NRF2 / 加齢 / 線維化 / 酸化ストレス応答 / 遺伝学的アンドロゲン高産生マウス / 細胞外マトリックス / 抗酸化剤 / PCOS / 細胞増殖 / 細胞死 / 卵胞 / 酸化ストレス / 細胞・組織 / 発生医学 / 遺伝学的細胞除去 / 尿管芽 / ミュラー管 / マイクロCT / 尿生殖洞 / 女性生殖器 / 腎管 / 3Dイメージング / 3次元イメージング / 尿直腸中隔 / 遺伝学的細胞標識 / Hhシグナル / 臍帯下部領域 / 協調的器官形成 / Alx4 / 協調的発生 / 遺伝学的解析 / 細胞移動 / ヘッジホッグシグナル / 先天性疾患 / 器官形成 / 泌尿生殖器 … More
Except Principal Investigator
レポーターマウス / ナノ物質 / 神経発達症 / 細胞性免疫 / ペルフルオロノナン酸 / Adverse Outcome Pathway / 相対効力係数 / 有機フッ素化合物 / 抗甲状腺薬 / レポータートランスジェニックマウス / in vivoイメージング / 先天性疾患 / パラメータ / 外生殖器 / 尿道下裂 / 無脊椎動物 / RXR / EcR / ムラサキイガイ / システイン / 有機スズ類 / レチノイドX受容体 / 核内受容体 / トランスジェニックマウス / 17β-ヒドロキシステロイド脱水素酵素 / 外性器形成 / アンドロゲン Less
  • Research Projects

    (12 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (21 People)
  •  Foundational Research for Establishing a Comprehensive Risk Assessment of PFAS-induced Developmental Neurotoxicity

    • Principal Investigator
      中西 剛
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 63:Environmental analyses and evaluation and related fields
    • Research Institution
      Gifu Pharmaceutical University
  •  母体免疫誘導による神経発達症リスク回避を目指したワクチン開発に資する基盤研究

    • Principal Investigator
      石田 慶士
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Gifu Pharmaceutical University
  •  ナノ物質の生体内ダイナミクス解析による量-反応評価

    • Principal Investigator
      田中 佑樹
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63030:Chemical substance influence on environment-related
    • Research Institution
      Chiba University
  •  尿道下裂リスク診断法開発のための多元的パラメータ解析

    • Principal Investigator
      井戸 章子
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Gihu University of Medical Science
  •  多嚢胞性卵巣症候群モデルマウスの微小炎症を標的とした病態制御研究Principal Investigator

    • Principal Investigator
      松丸 大輔
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Gifu Pharmaceutical University
  •  Refinement of the theory to evaluate developmental neurotoxicity of chemical substances that induce hypothyroidism

    • Principal Investigator
      永瀬 久光
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Gihu University of Medical Science
  •  Establishment of XX disorder of sex development model mice and the development of its pharmacological treatment

    • Principal Investigator
      Nakanishi Tsuyoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Gifu Pharmaceutical University
  •  Evolutionary analysis of the nuclear receptors in invertebrates to infer ecological effects of environmental chemicals.

    • Principal Investigator
      Hiromori Youhei
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63030:Chemical substance influence on environment-related
    • Research Institution
      Suzuka University of Medical Science
  •  The effects of stress response system in the ovary: KEAP1-NRF2 system and female infertilityPrincipal Investigator

    • Principal Investigator
      MATSUMARU Daisuke
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Gifu Pharmaceutical University
  •  Analysis of the transition of tubular structure in urogenital organsPrincipal Investigator

    • Principal Investigator
      MATSUMARU Daisuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
      Wakayama Medical University
  •  Genetic and streoscopic analyses for the pathogenic mechanisms of anorectal malformationsPrincipal Investigator

    • Principal Investigator
      MATSUMARU Daisuke
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Wakayama Medical University
  •  The analyses for the mechanisms of the coordinated development of the lower bodyPrincipal Investigator

    • Principal Investigator
      MATSUMARU Daisuke
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Wakayama Medical University

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

  • [Book] 小児泌尿器科学 I-7. 生殖器の発生(外生殖器の発生)2021

    • Author(s)
      藤本幸太、松丸大輔、村嶋亜紀、水野健太郎、林祐太郎、鈴木堅太郎、山田源
    • Total Pages
      4
    • Publisher
      診断と治療社
    • ISBN
      9784787824226
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Book] 小児泌尿器科学 I-4. 膀胱と尿道の発生2021

    • Author(s)
      日向泰樹、中井秀郎、中村繁、林祐太郎、水野健太郎、松丸大輔、村嶋亜紀、鈴木堅太郎、山田源
    • Total Pages
      6
    • Publisher
      診断と治療社
    • ISBN
      9784787824226
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Journal Article] Novel, highly sensitive, in vivo screening method detects estrogenic activity at low doses of bisphenol A2023

    • Author(s)
      Ishida Keishi、Furukawa Motoshi、Kunitani Masataka、Yamagiwa Rai、Hiromori Youhei、Matsumaru Daisuke、Hu Jianying、Nagase Hisamitsu、Nakanishi Tsuyoshi
    • Journal Title

      Journal of Hazardous Materials

      Volume: 445 Pages: 130461-130461

    • DOI

      10.1016/j.jhazmat.2022.130461

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K12260
  • [Journal Article] The role of p63 in embryonic external genitalia outgrowth in mice2023

    • Author(s)
      Tanaka Kosei、Matsumaru Daisuke、Suzuki Kentaro、Yamada Gen、Miyagawa Shinichi
    • Journal Title

      Development, Growth & Differentiation

      Volume: 65 Issue: 2 Pages: 132-140

    • DOI

      10.1111/dgd.12840

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K19538, KAKENHI-PROJECT-21H02522
  • [Journal Article] Evaluation of the Estrogenic Action Potential of Royal Jelly by Genomic Signaling Pathway <i>in Vitro</i> and <i>in Vivo</i>2022

    • Author(s)
      Ishida Keishi、Matsumaru Daisuke、Shimizu Shinya、Hiromori Youhei、Nagase Hisamitsu、Nakanishi Tsuyoshi
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 45 Issue: 10 Pages: 1510-1517

    • DOI

      10.1248/bpb.b22-00383

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2022-10-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K12260
  • [Journal Article] Neuronal differentiation reporter mice as a new methodology for detecting in vivo developmental neurotoxicity2022

    • Author(s)
      Ishida Keishi、Tatsumi Kanoko、Minamigawa Yoshiki、Mori Kazuma、Matsumaru Daisuke、Nagase Hisamitsu、Kanda Yasunari、Takuma Kazuhiro、Nakanishi Tsuyoshi
    • Journal Title

      Biochemical Pharmacology

      Volume: 206 Pages: 115332-115332

    • DOI

      10.1016/j.bcp.2022.115332

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K06594
  • [Journal Article] NRF2 pathway activation attenuates ageing-related renal phenotypes due to α-klotho deficiency2022

    • Author(s)
      Zhao Mingyue、Murakami Shohei、Matsumaru Daisuke、Kawauchi Takeshi、Nabeshima Yo-ichi、Motohashi Hozumi
    • Journal Title

      The Journal of Biochemistry

      Volume: 171 Issue: 5 Pages: 579-589

    • DOI

      10.1093/jb/mvac014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-21K15358
  • [Journal Article] Skeletal muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice.2021

    • Author(s)
      Onoki T, Izumi Y, Takahashi M, Murakami S, Matsumaru D, Ohta N, Wati SM, Hatanaka N, Katsuoka F, Okutsu M, Yabe Y, Hagiwara Y, Kanzaki M, Bamba T, Itoi E, Motohashi H*.
    • Journal Title

      Redox Biol.

      Volume: 43 Pages: 101966-101966

    • DOI

      10.1016/j.redox.2021.101966

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05167, KAKENHI-PLANNED-17H06304, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-20H04118, KAKENHI-PROJECT-19K07361
  • [Journal Article] An ancestral nuclear receptor couple, PPAR-RXR, is exploited by organotins2021

    • Author(s)
      Capit?o Ana M.F.、Lopes-Marques M?nica、P?scoa In?s、Sainath S.B.、Hiromori Youhei、Matsumaru Daisuke、Nakanishi Tsuyoshi、Ruivo Raquel、Santos Miguel M.、Castro L. Filipe C.
    • Journal Title

      Science of The Total Environment

      Volume: 797 Pages: 149044-149044

    • DOI

      10.1016/j.scitotenv.2021.149044

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K12260, KAKENHI-PROJECT-18H03381
  • [Journal Article] Evaluation of the Skin-Sensitizing Potential of Brazilian Green Propolis2021

    • Author(s)
      Shiraishi Erina、Ishida Keishi、Matsumaru Daisuke、Ido Akiko、Hiromori Youhei、Nagase Hisamitsu、Nakanishi Tsuyoshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 24 Pages: 13538-13538

    • DOI

      10.3390/ijms222413538

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K12260
  • [Journal Article] Alginate-coated activated charcoal enhances fecal excretion of 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin in mice, with fewer side effects than uncoated one2021

    • Author(s)
      Dungkokkruad Pinyapach、Tomita Shunsuke、Hiromori Youhei、Ishida Keishi、Matsumaru Daisuke、Mekada Kyoko、Nagase Hisamitsu、Tanaka Keiichi、Nakanishi Tsuyoshi
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 46 Issue: 8 Pages: 379-389

    • DOI

      10.2131/jts.46.379

    • NAID

      130008070936

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K12260, KAKENHI-PROJECT-18H03381
  • [Journal Article] New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development2021

    • Author(s)
      Haraguchi Ryuma、Yamada Gen、Murashima Aki、Matsumaru Daisuke、Kitazawa Riko、Kitazawa Sohei
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 3 Pages: 1211-1211

    • DOI

      10.3390/ijms22031211

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-20K07229, KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-18K06832, KAKENHI-PROJECT-18K06938, KAKENHI-PROJECT-21K06755
  • [Journal Article] Triphenyl phosphate delayed pubertal timing and induced decline of ovarian reserve in mice as an estrogen receptor antagonist2021

    • Author(s)
      Ma Haojia、Ishida Keishi、Xu Chenke、Takahashi Kyosuke、Li Yu、Zhang Chenhao、Kang Qiyue、Jia Yingting、Hu Wenxin、Matsumaru Daisuke、Nakanishi Tsuyoshi、Hu Jianying
    • Journal Title

      Environmental Pollution

      Volume: 290 Pages: 118096-118096

    • DOI

      10.1016/j.envpol.2021.118096

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-18H03381
  • [Journal Article] The KEAP1-NRF2 System in Healthy Aging and Longevity2021

    • Author(s)
      Matsumaru Daisuke、Motohashi Hozumi
    • Journal Title

      Antioxidants

      Volume: 10 Issue: 12 Pages: 1929-1929

    • DOI

      10.3390/antiox10121929

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Journal Article] NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands2020

    • Author(s)
      Wati Sisca Meida、Matsumaru Daisuke、Motohashi Hozumi
    • Journal Title

      Redox Biology

      Volume: 36 Pages: 101603-101603

    • DOI

      10.1016/j.redox.2020.101603

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02621
  • [Journal Article] Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss2020

    • Author(s)
      Oishi Tetsuya、Matsumaru Daisuke、Ota Nao、Kitamura Hiroshi、Zhang Tianxiang、Honkura Yohei、Katori Yukio、Motohashi Hozumi
    • Journal Title

      npj Aging and Mechanisms of Disease

      Volume: 6 Issue: 1 Pages: 14-14

    • DOI

      10.1038/s41514-020-00053-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-18H02949, KAKENHI-PROJECT-18K16826
  • [Journal Article] KEAP1-NRF2系制御による健康長寿.2020

    • Author(s)
      松丸大輔, 本橋ほづみ.
    • Journal Title

      糖尿病・内分泌代謝科

      Volume: 50 Pages: 190-196

    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Journal Article] From germ cells to neonates: the beginning of life and the KEAP1-NRF2 system.2020

    • Author(s)
      Matsumaru D, Motohashi H.
    • Journal Title

      J Biochem.

      Volume: 167 Pages: 133-138

    • DOI

      10.1093/jb/mvz070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621
  • [Journal Article] Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers2020

    • Author(s)
      Okazaki Keito、Anzawa Hayato、Liu Zun、Ota Nao、Kitamura Hiroshi、Onodera Yoshiaki、Alam Md. Morshedul、Matsumaru Daisuke、et al.
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 5911-5911

    • DOI

      10.1038/s41467-020-19593-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-19K07379, KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K16350, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08617
  • [Journal Article] Nrf2 suppresses oxidative stress and inflammation in APP knock-in Alzheimer's disease model mice2020

    • Author(s)
      3)(*Equal contribution) Uruno A*, Matsumaru D*, Ryoke R, Saito R, Kadoguchi S, Saigusa D, Saito T, Saido TC, Kawashima R, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 40 Issue: 6

    • DOI

      10.1128/mcb.00467-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-16KK0195
  • [Journal Article] Gli3 is a Key Factor in the Schwann Cells from Both Intact and Injured Peripheral Nerves2020

    • Author(s)
      Yamada Yurie、Trakanant Supaluk、Nihara Jun、Kudo Takehisa、Seo Kenji、Saeki Makio、Kurose Masayuki、Matsumaru Daisuke、Maeda Takeyasu、Ohazama Atsushi
    • Journal Title

      Neuroscience

      Volume: 432 Pages: 229-239

    • DOI

      10.1016/j.neuroscience.2020.02.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Journal Article] Tri-substituted organotin compounds, but not retinoic acid, are potent ligands of complement component 8 γ2020

    • Author(s)
      Yamamoto Katsuya、Hiromori Youhei、Matsumaru Daisuke、Ishii Yoichiro、Takeshita Yuki、Tsubakihara Iori、Kimura Tomoki、Nagase Hisamitsu、Nakanishi Tsuyoshi
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 45 Issue: 9 Pages: 581-587

    • DOI

      10.2131/jts.45.581

    • NAID

      130007895029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-18K06737, KAKENHI-PROJECT-18H03381
  • [Journal Article] Evaluation of surgical procedures of mouse urethra by visualization and the formation of fistula2020

    • Author(s)
      Hyuga Taiju、Hashimoto Daiki、Matsumaru Daisuke、Kumegawa Shinji、Asamura Shinichi、Suzuki Kentaro、Katayama Kei-ichi、Nakamura Shigeru、Nakai Hideo、Yamada Gen
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 18251-18251

    • DOI

      10.1038/s41598-020-75184-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-20K18150, KAKENHI-PROJECT-17K11194, KAKENHI-PROJECT-18K06837, KAKENHI-PROJECT-18K06938
  • [Journal Article] Epispadias and the associated embryopathies; genetic and developmental basis.2017

    • Author(s)
      Kentaro Suzuki, Daisuke Matsumaru, Shoko Matsushita, Aki Murashima, Michael Ludwig, Heiko Reuter, Gen Yamada
    • Journal Title

      Clinical Genetics

      Volume: 91 Issue: 2 Pages: 247-253

    • DOI

      10.1111/cge.12871

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15J11033, KAKENHI-PROJECT-15K10647, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-17K18024, KAKENHI-PROJECT-15H04300, KAKENHI-PROJECT-26860196, KAKENHI-PROJECT-16K08595
  • [Journal Article] Investigation of sexual dimorphisms through mouse models and hormone/hormone-disruptor treatments2016

    • Author(s)
      Ipulan LA, Raga D, Suzuki K, Murashima A, Matsumaru D, Cunha G, Yamada G.
    • Journal Title

      Differentiation

      Volume: 印刷中 Issue: 4-5 Pages: 30072-4

    • DOI

      10.1016/j.diff.2015.11.001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10647, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-26860196, KAKENHI-PROJECT-16K08595
  • [Journal Article] Systematic stereoscopic analyses for cloacal development: The origin of anorectal malformations.2015

    • Author(s)
      Matsumaru D, Murashima A, Fukushima J, Senda S, Matsushita S, Nakagata N, Miyajima M, Yamada G.
    • Journal Title

      Sci Rep.

      Volume: 10;5 Issue: 1 Pages: 13943-13943

    • DOI

      10.1038/srep13943

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15403, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-26860196, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04300, KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-15J11033
  • [Journal Article] T396I Mutation of Mouse Sufu Reduces the Stability and Activity of Gli3 Repressor2015

    • Author(s)
      Makino S, Zhulyn O, Mo R, Puviindran V, Zhang X, Murata T, Fukumura R, Ishitsuka Y, Kotaki H, Matsumaru D, Ishii S, Hui C.C, Gondo Y
    • Journal Title

      PLOS ONE

      Volume: 10 Issue: 3 Pages: e0119455-e0119455

    • DOI

      10.1371/journal.pone.0119455

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25440096, KAKENHI-PROJECT-26291006, KAKENHI-PROJECT-26860196
  • [Journal Article] 増大特集 細胞シグナル操作法 Ⅰ.分子からみたシグナル操作法 4.その他 ヘッジホッグシグナル2015

    • Author(s)
      松丸大輔、山田源
    • Journal Title

      生体の科学

      Volume: 66 Issue: 5 Pages: 442-443

    • DOI

      10.11477/mf.2425200298

    • ISSN
      0370-9531, 1883-5503
    • Year and Date
      2015-10-15
    • Data Source
      KAKENHI-PROJECT-26860196
  • [Journal Article] Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations.2014

    • Author(s)
      Ng RC, Matsumaru D, Ho AS, Garcia-Barcelo MM, Yuan ZW, Smith D, Kodjabachian L, Tam PK, Yamada G, Lui VC.
    • Journal Title

      Cell Death & Differentiation

      Volume: 21 Issue: 6 Pages: 978-989

    • DOI

      10.1038/cdd.2014.20

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24790292
  • [Journal Article] Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations2014

    • Author(s)
      Miyagawa S, Harada M, Matsumaru D, Tanaka K, Inoue C, Nakahara C, Haraguchi R, Matsushita S, Suzuki K, Nakagata N, Ng RC, Akita K, Lui VC, Yamada G.
    • Journal Title

      Cell Death Differ.

      Volume: 21 Issue: 6 Pages: 990-997

    • DOI

      10.1038/cdd.2014.21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590216, KAKENHI-PROJECT-24590235, KAKENHI-PROJECT-24790292, KAKENHI-PROJECT-25860143, KAKENHI-PROJECT-25870202, KAKENHI-PROJECT-26440173
  • [Journal Article] Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation,2014

    • Author(s)
      Daisuke Matsumaru, Ryuma Haraguchi, Anne M. Moon, Yoshihiko Satoh, Naomi Nakagata, Ken-ichi Yamamur, Naoki Takahashi, Sohei Kitazawa, Gen Yamada.
    • Journal Title

      Eur J Hum Genet

      Volume: 22(3) Issue: 3 Pages: 350-357

    • DOI

      10.1038/ejhg.2013.160

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22132006, KAKENHI-PROJECT-23659186, KAKENHI-PROJECT-24790292, KAKENHI-PROJECT-25860143, KAKENHI-PROJECT-221S0001
  • [Journal Article] Retinoic acid signaling regulates Sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development2012

    • Author(s)
      Liu L, Suzuki K, et al
    • Journal Title

      Birth Defects Res B Dev Reprod Toxico

      Volume: 95 Issue: 1 Pages: 79-88

    • DOI

      10.1002/bdrb.20344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790323, KAKENHI-PROJECT-23570085, KAKENHI-PROJECT-24790292
  • [Journal Article] The Hedgehog Signal Induced Modulation of Bone Morphogenetic Proteins Signaling : An Essential Signaling Relay for Urinary Tract Morphogenesis2012

    • Author(s)
      Ryuma Haraguchi, Daisuke Matsumaru, Naomi Nakagata, Shinichi Miyagawa, Kentaro Suzuki, Sohei Kitazawa, Gen Yamada
    • Journal Title

      PLoS One

      Volume: 7(7) Issue: 7 Pages: e42245-e42245

    • DOI

      10.1371/journal.pone.0042245

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659186, KAKENHI-PROJECT-23790228, KAKENHI-PROJECT-24590235, KAKENHI-PROJECT-24790292
  • [Presentation] Establishment and characterization of genetic mouse model of polycysticovary syndrome2023

    • Author(s)
      Daisuke Matsumaru, Riko Yoshida, Yuta Mori, Keishi Ishida, Kyoko Mekada, Hozumi Motohashi, Tsuyoshi Nakanishi
    • Organizer
      2023 Japan/Korea Joint Symposium on Pharmaceutical Health Science and Environmental Toxicology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Presentation] ムラサキイガイ Retinoid X receptor の単一アミノ酸変異がその機能に及ぼす影響と変異割合の調査2022

    • Author(s)
      筒井 良一,廣森 洋平,水谷 奏女,石田 慶士,松丸 大輔,永瀬 久光,濱田 稔,菊田 武司,野方 靖行,中西 剛
    • Organizer
      フォーラム2022 衛生薬学・環境トキシコロジー
    • Data Source
      KAKENHI-PROJECT-21K12260
  • [Presentation] 遺伝学的アンドロゲン高産生マウスの多嚢胞性卵巣症候群様症状は酸化ストレス制御によって改善されうる2022

    • Author(s)
      吉田 莉子、松丸 大輔、石田 慶士、目加田 京子、本橋 ほづみ、中西 剛
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Presentation] The roles of Nrf2 in oxidative stress and neuroinflammation in App knock-in Alzheimer’s diseases model mice.2019

    • Author(s)
      Uruno A, Matsumaru D, Ryoke R, Saito R, Kadoguchi S, Saigusa D, Saito T, Saido TC, Kawashima R, Motohashi H, Yamamoto M
    • Organizer
      The Environmental Response V.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Presentation] Activation of KEAP1-NRF2 system mitigates oxidative stress and neuroinflammation in the Alzheimer’s disease model.2019

    • Author(s)
      (*Equal contribution) Uruno A*, Matsumaru D*, Ryoke R*, Saito R, Saigusa D, Saito T, Saido TC, Kawashima R, Yamamoto M.
    • Organizer
      Alzheimer's Association International Conference 2019.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361
  • [Presentation] 胎児上部泌尿器系異常の発症メカニズム研究: 総排泄腔上皮由来ヘッジホッグシグナルの遺伝学的機能解析2014

    • Author(s)
      松丸 大輔, 原口 竜摩, 山田 源
    • Organizer
      日本薬学会 第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PROJECT-24790292
  • [Presentation] Genetic Analysis of the Role of Hedgehog Signaling in the Coordination of Lower Body Formation2013

    • Author(s)
      Matsumaru D, Haraguchi R, Miyagawa S, Satoh Y, Suzuki K, Yamada G.
    • Organizer
      The 61st NIBB Conference "Cellular Community in Mammalian Embryogenesis"
    • Place of Presentation
      Okazaki, Aichi, Japan
    • Data Source
      KAKENHI-PROJECT-24790292
  • [Presentation] ミュータントマウスシリーズのご紹介;生殖、発生、毒性評価との接点

    • Author(s)
      松丸大輔
    • Organizer
      関西生殖発生毒性フォーラム
    • Place of Presentation
      弁天町市民学習センター
    • Data Source
      KAKENHI-PROJECT-24790292
  • 1.  Nakanishi Tsuyoshi (50303988)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 2.  石田 慶士 (90908310)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  田熊 一敞 (90289025)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  目加田 京子 (40898235)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Hiromori Youhei (60515956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  水野 健太郎 (70448710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  井戸 章子 (00336629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  永瀬 久光 (40141395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  早田 敦子 (70390812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  田中 佑樹 (50824041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  YAMADA gen
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  KAJIMOTO mizuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SUZUKI Kentaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  松下 祥子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  和泉 自泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  権藤 洋一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  牧野 茂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  原田 理代
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  秋田 恵一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  北澤 理子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  北澤 荘平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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