Hiraga Nobuhiko 平賀伸彦

Researcher Number	50625978
Affiliation (based on the past Project Information) *help	2016 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 客員研究員 2015: 広島大学, 医歯薬保健学研究院, 助教
Review Section/Research Field	Principal Investigator Gastroenterology
Keywords	Principal Investigator B型肝炎ウイルス / マウス / HBV / ｃｃｃDNA

The search of the drug for the acute severe HBV hepatitis using animal modelPrincipal Investigator
- Principal Investigator
  
  Hiraga Nobuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Institute of Physical and Chemical Research
  Hiroshima University

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice.2017
- Author(s)
  Uchida T, Imamura M, Hayes CN, Hiraga N, Kan H, Tsuge M, Abe-Chayama H, Zhang Y, Makokha GN, Aikata H, Miki D, Ochi H, Ishida Y, Tateno C, Chayama K
- Journal Title
  
  Antimicrob Agents Chemother.
  
  Volume: 61
- DOI
  10.1128/aac.00725-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09427, KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-16K19346
[Journal Article] Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection2017
- Author(s)
  Tsuge M, Hiraga N, Uchida T, Kan H, Miyaki E, Masaki K, Ono A, Nakahara T, Abe-Chayama H, Zhang Y, Naswa MG, Kawaoka T, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Chayama K.
- Journal Title
  
  J Gastroenterol
  
  Volume: In press Pages: 1073-1080
- DOI
  10.1007/s00535-016-1189-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860191, KAKENHI-PROJECT-15K15293, KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-16K19346
[Journal Article] Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice.2015
- Author(s)
  Uchida T., Hiraga N., Imamura M., Tsuge M., Abe H., Hayes C.N., Aikata H., Ishida Y., Tateno C., Yoshizato K., Ohdan H., Murakami K. and Chayama K.
- Journal Title
  
  J Virol.
  
  Volume: 89 Pages: 10087-10096
- DOI
  10.1128/jvi.01126-15
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09002, KAKENHI-PROJECT-15K09003, KAKENHI-PROJECT-26420796
[Presentation] Human cytotoxic T lymphocyte mediated acute liver failure and rescue by immunoglobulin in human hepatocyte transplanted TKNOG mice2016
- Author(s)
  Uchida T, Hiraga N, Imamura M, Yoshimi S, Kan H, Miyaki E, Tsuge M, Abe H, Hayes CN, Aikata H, Ishida Y, Tateno C, Ellis JD, Chayama
- Organizer
  Asian Pacific Association for the Study of the Liver.
- Place of Presentation
  東京（国際館パミール）
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09003
[Presentation] ヒト肝細胞キメラマウスを用いた急性B型肝炎モデルの構築2015
- Author(s)
  平賀伸彦，今村道雄，茶山一彰
- Organizer
  日本肝臓学会　第19回大会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K09003
[Presentation] Human cytotoxic T lymphocyte mediated acute liver failure and rescue by immunoglobulin in human hepatocyte transplanted TKNOG mice2015
- Author(s)
  Uchida T, Hiraga N, Imamura M, Yoshimi S, Kan H, Miyaki E, Tsuge M, Abe H, Hayes CN, Aikata H, Ishida Y, Tateno C, Ellis JD, Chayama K.
- Organizer
  2015 Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  サンフランシスコ
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09003

1. ABE Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. IMAMURA Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 柘植雅貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. ZHANG YIZHOU

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 茶山一彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hiraga Nobuhiko 平賀 伸彦

Research Projects

Research Products

Co-Researchers

The search of the drug for the acute severe HBV hepatitis using animal modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Human cytotoxic T lymphocyte mediated acute liver failure and rescue by immunoglobulin in human hepatocyte transplanted TKNOG mice2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒト肝細胞キメラマウスを用いた急性B型肝炎モデルの構築2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Human cytotoxic T lymphocyte mediated acute liver failure and rescue by immunoglobulin in human hepatocyte transplanted TKNOG mice2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Hiraga Nobuhiko 平賀伸彦