Kobayashi Miho 小林美穂

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KOBAYASHI Miho 小林美穂

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Researcher Number	50630539
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 大学院医歯学総合研究科, 助教 2019 – 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2018: 金沢医科大学, 医学部, 助教 2013 – 2017: 東北大学, 加齢医学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / General physiology / Basic Section 50010:Tumor biology-related / Tumor biology
Keywords	Principal Investigator 微小管 / 細胞内輸送 / 血管安定化 / VEGF / 血管新生 / 個体老化 / 細胞内輸送制御 / 脱チロシン化 / 寿命 / 臓器向性 … More / 血管 / がん転移 / 血管バリア崩壊 / エクソソーム / EndoMT/EndMT / TGF-β / 血管不安定化 / 内皮間葉移行 / 細胞外小胞 / 腫瘍 / Tie2 / VE-カドヘリン / 血管の安定化 / 腫瘍血管 / 細胞間接着分子 / 受容体探索 / 抗血管新生 / シグナル伝達 / Vasohibin-1 Less

Biological role of vasohibin-1Principal Investigator
- Principal Investigator
  
  小林美穂
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Institute of Science Tokyo
Vasohibin-1による個体寿命制御機構の解明Principal Investigator
- Principal Investigator
  
  小林美穂
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Medical and Dental University
Role of vascular in distant metastasis of oral cancer and its molecular mechanismsPrincipal Investigator
- Principal Investigator
  
  Kobayashi Miho
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the mechanism of vascular stabilization by vasohibin-1 aimed at the establishment of anti-tumor therapy.(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Kobayashi Miho
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa Medical University
  Tohoku University
Elucidation of vascular stabilization mechanism by anti-angiogenic factor vasohibin-1Principal Investigator
- Principal Investigator
  
  Kobayashi Miho
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Tohoku University
Vasohibin-1 signaling mechanismPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Miho
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] 口腔がん細胞由来エクソソームによる内皮不安定化機構2023
- Author(s)
  小林美穂、藤原花汐、高橋和樹、吉岡祐亮、落谷孝広、井上カタジナアンナ、渡部徹郎
- Journal Title
  
  リンパ学
  
  Volume: 46 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07674
[Journal Article] Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal transition2022
- Author(s)
  Kobayashi Miho、Fujiwara Kashio、Takahashi Kazuki、Yoshioka Yusuke、Ochiya Takahiro、Podyma-Inoue Katarzyna A.、Watabe Tetsuro
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1 Pages: 38-38
- DOI
  10.1186/s41232-022-00225-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03851, KAKENHI-PROJECT-19K07674, KAKENHI-PROJECT-20K10111
[Journal Article] TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation2020
- Author(s)
  Yasuhiro Yoshimatsu, Ikumi Wakabayashi, Shiori Kimuro, Naoya Takahashi, Kazuki Takahashi, Miho Kobayashi, Nako Maishi, Katarzyna A. Podyma-Inoue, Kyoko Hida, Kohei Miyazono, Tetsuro Watabe
- Journal Title
  
  Cancer Sciense
  
  Volume: - Issue: 7 Pages: 2385-2399
- DOI
  10.1111/cas.14455
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07674, KAKENHI-PROJECT-20K09900, KAKENHI-PROJECT-20J11926, KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-17K11828, KAKENHI-PROJECT-18K09715, KAKENHI-PROJECT-18H02996, KAKENHI-PROJECT-20H03851
[Journal Article] Tubulin carboxypeptidase activity of vasohibin-1 inhibits angiogenesis by interfering with endocytosis and trafficking of pro-angiogenic factor receptors2020
- Author(s)
  Kobayashi Miho、Wakabayashi Ikumi、Suzuki Yasuhiro、Fujiwara Kashio、Nakayama Masanori、Watabe Tetsuro、Sato Yasufumi
- Journal Title
  
  Angiogenesis
  
  Volume: 24 Issue: 1 Pages: 159-176
- DOI
  10.1007/s10456-020-09754-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07674, KAKENHI-PROJECT-20H03851
[Journal Article] Antiangiogenic Effects of VH02, a Novel Urea Derivative: In Vitro and in Vivo Studies.2016
- Author(s)
  Phowichit S, Kobayashi M, Fujinoya Y, Sato Y, Sanphanya K, Vajragupta O, Chularojmontri L, Wattanapitayakul SK.
- Journal Title
  
  Molecules
  
  Volume: 21 Issue: 9 Pages: 1258-1258
- DOI
  10.3390/molecules21091258
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20874
[Journal Article] Distinctive role of vasohibin-1A and its splicing variant vasohibin-1B in tumor angiogenesis2016
- Author(s)
  Sachiko Horie, Yasuhiro Suzuki, Miho Kobayashi, Tetsuya Kadonosono, Shinae Kondoh, Tetsuya Kodama and Yasufumi Sato.
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: in press Issue: 5 Pages: 133-141
- DOI
  10.1038/cgt.2016.13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20874
[Journal Article] Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation.2014
- Author(s)
  Kaori Suenaga, Shuji Kitahara, Yasuhiro Suzuki, Miho Kobayashi, Sachiko Horie, Junichi Sugawara, Nobuo Yaegashi, Yasufumi Sato
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870070
[Journal Article] Enhanced cancer metastasis in mice deficient in vasohibin-1 gene.2013
- Author(s)
  Soichi Ito, Hiroki Miyashita, Yasuhiro Suzuki, Miho Kobayashi, Susumu Satomi, Yasufumi Sato
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 9 Pages: e73931-e73931
- DOI
  10.1371/journal.pone.0073931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] 口腔がん細胞由来エクソソームによる内皮不安定化機構2022
- Author(s)
  小林美穂、藤原花汐、高橋和樹、井上カタジナアンナ、渡部徹郎
- Organizer
  第46回日本リンパ学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 口腔がん細胞が放出するエクソソームによる血管不安定化機構2022
- Author(s)
  小林美穂
- Organizer
  第7回血管生物医学会若手研究会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 口腔扁平上皮がん細胞由来細胞外小胞による血管不安定化機構2022
- Author(s)
  小林美穂、藤原花汐、高橋和樹、吉岡祐亮、落谷孝広、渡部徹郎
- Organizer
  第87回口腔病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 口腔扁平上皮がん細胞が放出するエクソソームによるがん悪性化誘導機構2021
- Author(s)
  藤原花汐, 小林美穂, 井上カタジナアンナ, 渡部徹郎
- Organizer
  第44回日本分子生物学会年会（MBSJ2021）
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Novel anti-angiogenic mechanism of VASH1 through the modification of microtubules2021
- Author(s)
  Miho Kobayashi、Kashio Fujiwara、Ikumi Wakabayashi、Yasuhiro Suzuki、Masanori Nakayama、Yasufumi Sato、Tetsuro Watabe
- Organizer
  CVMW2020心血管代謝週間（第28回日本血管生物医学会学術集会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 口腔扁平上皮がん細胞が放出するエクソソームによる血管不安定化機構2021
- Author(s)
  小林美穂、藤原花汐、井上カタジナアンナ、渡部徹郎
- Organizer
  第29回日本血管生物医学会学術集会（CVMW2021）
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介したシグナル伝達の調節機構2021
- Author(s)
  小林美穂、若林育海、鈴木康弘、藤原花汐、中山雅敬、佐藤靖史、渡部徹郎
- Organizer
  第85回口腔病学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1が誘導する微小管の翻訳後修飾を介した受容体エンドサイトーシス阻害と新規脈管新生抑制機構2021
- Author(s)
  小林美穂、若林育海、藤原花汐、鈴木康弘、中山雅敬、佐藤靖史、渡部徹郎
- Organizer
  第45回日本リンパ学会総会（JSL2021）
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] TNF-αはTGF-βシグナルの増強を介してTGF-βによって誘導される血管の内皮間葉移行を促進する2020
- Author(s)
  若林育海、吉松康裕、紀室志織、高橋直也、高橋和樹、伊東史子、小林美穂、井上カタジナアンナ、宮園浩平、渡部徹郎.
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] - Novel inhibition mechanism of signaling - Anti-angiogenic mechanism by vasohibin-12020
- Author(s)
  Miho Kobayashi
- Organizer
  第6回日本血管生物学会若手研究会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1 induced post-translational modification of microtubules mediates VEGF-signaling in angiogenesis2020
- Author(s)
  Miho KOBAYASHI, Ikumi Wakabayashi, Yasuhiro Suzuki, Kashio Fujiwara, Masanori Nakayama, Yasufumi Sato, Tetsuro Watabe
- Organizer
  第42回日本分子生物学会年会（MBSJ2020）
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1 Inhibits Angiogenesis via the Increase of Detyrosinated α-Tubulin2020
- Author(s)
  Miho Kobayashi、Ikumi Wakabayashi、Kashio Fujiwara、Yasuhiro Suzuki、Masanori Nakayama、Yasufumi Sato、Tetsuro Watabe
- Organizer
  The 21st International Vascular Biology Meeting (IVBM2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介した機能とその役割2019
- Author(s)
  小林美穂、鈴木康弘、中山雅敬、佐藤靖史
- Organizer
  血管生物学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介したVEGFシグナル伝達調節2019
- Author(s)
  小林美穂, 若林育海, 鈴木康弘, 渡部徹郎, 佐藤靖史
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1による血管新生抑制の分子機構2019
- Author(s)
  小林美穂, 若林育海, 鈴木康弘, 中山雅敬, 渡部徹郎, 佐藤靖史
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 血管・リンパ管形成調節因子バソヒビン-1による血管新生抑制の分子機構2019
- Author(s)
  小林美穂、若林育海、鈴木康弘、中山雅敬、渡部徹郎、佐藤靖史
- Organizer
  第1回 New Lymphology Research Conference
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 血管新生ネガティブフィードバック因子：Vasohibin-1による微小管の翻訳後修飾を介した血管新生抑制機構2019
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第48回日本心脈管作動物質学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1 による微小管の翻訳後修飾とその機能2019
- Author(s)
  小林美穂、鈴木康弘、中山雅敬、佐藤靖史
- Organizer
  第14回 Vasohibin研究会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] The post-translational modification of microtubules mediates angiogenic signaling.2017
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  The 2017 Japan-NIH joint Symposium
- Place of Presentation
  Seiryo Auditorium, Seiryo Campus, Tohoku University, Japan
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] The role of vasohibin-1-mediated post-translational modification of microtubules.2017
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  第12回Vasohibin研究会
- Place of Presentation
  ラフォーレ蔵王リゾート&スパ（宮城県・蔵王町）
- Year and Date
  2017-02-04
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] Vasohibin-1による血管新生シグナル伝達阻害機構2016
- Author(s)
  小林美穂
- Organizer
  第11回Vasohibin研究会
- Place of Presentation
  ラフォーレ蔵王（宮城県・蔵王町）
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] バソヒビン-1 による微小管の翻訳後修飾が内皮細胞に与える影響2016
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第2回血管生物若手研究会
- Place of Presentation
  東北大学加齢医学研究所国際会議室（宮城県・仙台市）
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] The post-translational modification of microtubules mediates receptor signaling.2016
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  2016 ASCB Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] Regulation of receptor signaling by MTs post-translational modification.2016
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  第39回日本分子生物学会年会（MBSJ2016）
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] Vasohibin-2 標的性 BAN 修飾アンチセンスオリゴヌクレオチドを用いた新規分子標的性肝がん治療2015
- Author(s)
  堀江佐知子、鈴木康弘、小林美穂、小玉哲也、佐藤靖史
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] バソヒビン－1による細胞内輸送阻害を介したVEGF及びFGF2シグナル伝達阻害2015
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第23回日本血管生物医学会学術集会 (CVMW2015)
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] バソヒビン-1によるVEGF及びFGF2シグナル伝達阻害と抗血管新生2015
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会 (BMB2015)
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] 音響性リポソームと超音波を用いたVasohibin-1遺伝子導入による抗血管新生効果の評価2014
- Author(s)
  堀江佐知子、鈴木康弘、小林美穂、小玉哲也、佐藤靖史
- Organizer
  第13回日本超音波治療研究会（JSTU2014）
- Place of Presentation
  仙台情報・産業プラザ　多目的ホール（宮城県・仙台市）
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Distinctive roles of Vasohibin-1A and Vasohibin-1B in angiogenesis regulation2014
- Author(s)
  Sachiko Horie, Yasuhiro Suzuki, Miho Kobayashi, Yasufumi Sato
- Organizer
  第22回日本血管生物医学会学術集（併：第18回国際血管生物学会IVBM）
- Place of Presentation
  京都、京都市勧業館みやこめっせ
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] ナノ・マイクロバブルと超音波を用いたVasohibin-1遺伝子導入による抗腫瘍効果の評価2014
- Author(s)
  堀江佐知子、小林美穂、鈴木康弘、小玉哲也、佐藤靖史
- Organizer
  第26回バイオエンジニアリング講演会
- Place of Presentation
  仙台、東北大学片平さくらホール
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介したVEGFシグナル伝達の新規抑制機構2013
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸、神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1が誘導する微小管翻訳後修飾とVEGFシグナル伝達との関係2013
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪、千里阪急ホテル
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Role of the vasohibin family in the regulation of placental morphogenesis
- Author(s)
  Kaori Suenaga, Shuji Kitahara, Yasuhiro Suzuki, Miho Kobayashi, Sachiko Horie, Junichi Sugawara, Nobuo Yaegashi, Yasufumi Sato
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Distinctive roles of Vasohibin-1A and Vasohibin-1B in angiogenesis regulation
- Author(s)
  Sachiko Horie, Yasuhiro Suzuki, Miho Kobayashi, Yasufumi Sato
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による抗血管新生効果の作用機序
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Development of a novel anti-angiogenic cancer therapy targeting vasohibin-2
- Author(s)
  Takahiro Koyanagi, Yasuhiro Suzuki, Miho Kobayashi, Hiroki Miyashita, Yasushi Saga, Mitsuaki Suzuki, Yasufumi Sato
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] 抗血管新生効果における Vasohibin-1A と Vasohibin-1B の役割
- Author(s)
  堀江佐知子、鈴木康弘、小林美穂、小玉哲也、佐藤靖史
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1 induces suppression of VEGF-signaling via post- translational modification of MTs.
- Author(s)
  Miho Kobayashi
- Organizer
  The 10th Vasohibin Meeting
- Place of Presentation
  ラフォーレ蔵王リゾート＆スパ（宮城県・蔵王町）
- Year and Date
  2015-01-10 – 2015-01-11
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による抗血管新生メカニズム
- Author(s)
  小林美穂
- Organizer
  第１回血管生物若手研究会
- Place of Presentation
  東京大学医学部教育研究棟2階第1・2セミナー室（東京都）
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-25870070

1. Nakayama Masanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Graumann Johannes

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 渡部徹郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Miho 小林 美穂

KOBAYASHI Miho 小林 美穂

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Biological role of vasohibin-1Principal Investigator

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Vasohibin-1による個体寿命制御機構の解明Principal Investigator

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Role of vascular in distant metastasis of oral cancer and its molecular mechanismsPrincipal Investigator

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Elucidation of the mechanism of vascular stabilization by vasohibin-1 aimed at the establishment of anti-tumor therapy.(Fostering Joint International Research)Principal Investigator

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Elucidation of vascular stabilization mechanism by anti-angiogenic factor vasohibin-1Principal Investigator

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Vasohibin-1 signaling mechanismPrincipal Investigator

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[Journal Article] 口腔がん細胞由来エクソソームによる内皮不安定化機構2023

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[Journal Article] Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal transition2022

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[Journal Article] TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation2020

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[Journal Article] Tubulin carboxypeptidase activity of vasohibin-1 inhibits angiogenesis by interfering with endocytosis and trafficking of pro-angiogenic factor receptors2020

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[Journal Article] Antiangiogenic Effects of VH02, a Novel Urea Derivative: In Vitro and in Vivo Studies.2016

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[Journal Article] Distinctive role of vasohibin-1A and its splicing variant vasohibin-1B in tumor angiogenesis2016

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[Journal Article] Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation.2014

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[Journal Article] Enhanced cancer metastasis in mice deficient in vasohibin-1 gene.2013

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[Presentation] 口腔がん細胞由来エクソソームによる内皮不安定化機構2022

Kobayashi Miho 小林美穂

KOBAYASHI Miho 小林美穂

[Presentation] TNF-αはTGF-βシグナルの増強を介してTGF-βによって誘導される血管の内皮間葉移行を促進する2020