Kobayashi Miho 小林美穂

… Alternative Names

Researcher Number	50630539
Other IDs
Affiliation (Current)	2021: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
Affiliation (based on the past Project Information) *help	2019: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2018: 金沢医科大学, 医学部, 助教 2013 – 2017: 東北大学, 加齢医学研究所, 助教
Review Section/Research Field	Principal Investigator Tumor biology / General physiology / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 血管新生 / VEGF / 血管安定化 / 微小管 / Vasohibin-1 / シグナル伝達 / 抗血管新生 / 受容体探索 / 細胞間接着分子 / 腫瘍血管 … More

腫瘍の臓器向性転移における血管の役割とその分子機構Principal InvestigatorOngoing
- Principal Investigator
  
  小林美穂
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the mechanism of vascular stabilization by vasohibin-1 aimed at the establishment of anti-tumor therapy.(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Kobayashi Miho
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa Medical University
  Tohoku University
Elucidation of vascular stabilization mechanism by anti-angiogenic factor vasohibin-1Principal Investigator
- Principal Investigator
  
  Kobayashi Miho
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
  General physiology
- Research Institution
  Tohoku University
Vasohibin-1 signaling mechanismPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Miho
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
  General physiology
- Research Institution
  Tohoku University

All 2020 2019 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation2020
- Author(s)
  Yasuhiro Yoshimatsu, Ikumi Wakabayashi, Shiori Kimuro, Naoya Takahashi, Kazuki Takahashi, Miho Kobayashi, Nako Maishi, Katarzyna A. Podyma-Inoue, Kyoko Hida, Kohei Miyazono, Tetsuro Watabe
- Journal Title
  
  Cancer Sciense
  
  Volume: -
- DOI
  10.1111/cas.14455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07674
[Journal Article] Antiangiogenic Effects of VH02, a Novel Urea Derivative: In Vitro and in Vivo Studies.2016
- Author(s)
  Phowichit S, Kobayashi M, Fujinoya Y, Sato Y, Sanphanya K, Vajragupta O, Chularojmontri L, Wattanapitayakul SK.
- Journal Title
  
  Molecules
  
  Volume: 21 Pages: 1258-1258
- DOI
  10.3390/molecules21091258
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20874
[Journal Article] Distinctive role of vasohibin-1A and its splicing variant vasohibin-1B in tumor angiogenesis2016
- Author(s)
  Sachiko Horie, Yasuhiro Suzuki, Miho Kobayashi, Tetsuya Kadonosono, Shinae Kondoh, Tetsuya Kodama and Yasufumi Sato.
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: in press
- DOI
  10.1038/cgt.2016.13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20874
[Journal Article] Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation.2014
- Author(s)
  Kaori Suenaga, Shuji Kitahara, Yasuhiro Suzuki, Miho Kobayashi, Sachiko Horie, Junichi Sugawara, Nobuo Yaegashi, Yasufumi Sato
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870070
[Journal Article] Enhanced cancer metastasis in mice deficient in vasohibin-1 gene.2013
- Author(s)
  Soichi Ito, Hiroki Miyashita, Yasuhiro Suzuki, Miho Kobayashi, Susumu Satomi, Yasufumi Sato
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0073931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介した機能とその役割2019
- Author(s)
  小林美穂、鈴木康弘、中山雅敬、佐藤靖史
- Organizer
  血管生物学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介したVEGFシグナル伝達調節2019
- Author(s)
  小林美穂, 若林育海, 鈴木康弘, 渡部徹郎, 佐藤靖史
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1による血管新生抑制の分子機構2019
- Author(s)
  小林美穂, 若林育海, 鈴木康弘, 中山雅敬, 渡部徹郎, 佐藤靖史
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 血管・リンパ管形成調節因子バソヒビン-1による血管新生抑制の分子機構2019
- Author(s)
  小林美穂、若林育海、鈴木康弘、中山雅敬、渡部徹郎、佐藤靖史
- Organizer
  第1回 New Lymphology Research Conference
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] 血管新生ネガティブフィードバック因子：Vasohibin-1による微小管の翻訳後修飾を介した血管新生抑制機構2019
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第48回日本心脈管作動物質学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] Vasohibin-1 による微小管の翻訳後修飾とその機能2019
- Author(s)
  小林美穂、鈴木康弘、中山雅敬、佐藤靖史
- Organizer
  第14回 Vasohibin研究会
- Data Source
  KAKENHI-PROJECT-19K07674
[Presentation] The post-translational modification of microtubules mediates angiogenic signaling.2017
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  The 2017 Japan-NIH joint Symposium
- Place of Presentation
  Seiryo Auditorium, Seiryo Campus, Tohoku University, Japan
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] The role of vasohibin-1-mediated post-translational modification of microtubules.2017
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  第12回Vasohibin研究会
- Place of Presentation
  ラフォーレ蔵王リゾート&スパ（宮城県・蔵王町）
- Year and Date
  2017-02-04
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] Vasohibin-1による血管新生シグナル伝達阻害機構2016
- Author(s)
  小林美穂
- Organizer
  第11回Vasohibin研究会
- Place of Presentation
  ラフォーレ蔵王（宮城県・蔵王町）
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] バソヒビン-1 による微小管の翻訳後修飾が内皮細胞に与える影響2016
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第2回血管生物若手研究会
- Place of Presentation
  東北大学加齢医学研究所国際会議室（宮城県・仙台市）
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] The post-translational modification of microtubules mediates receptor signaling.2016
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  2016 ASCB Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco, CA, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] Regulation of receptor signaling by MTs post-translational modification.2016
- Author(s)
  Miho Kobayashi, Yasuhiro Suzuki, Yasufumi Sato.
- Organizer
  第39回日本分子生物学会年会（MBSJ2016）
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] Vasohibin-2 標的性 BAN 修飾アンチセンスオリゴヌクレオチドを用いた新規分子標的性肝がん治療2015
- Author(s)
  堀江佐知子、鈴木康弘、小林美穂、小玉哲也、佐藤靖史
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] バソヒビン－1による細胞内輸送阻害を介したVEGF及びFGF2シグナル伝達阻害2015
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第23回日本血管生物医学会学術集会 (CVMW2015)
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] バソヒビン-1によるVEGF及びFGF2シグナル伝達阻害と抗血管新生2015
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会 (BMB2015)
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K20874
[Presentation] 音響性リポソームと超音波を用いたVasohibin-1遺伝子導入による抗血管新生効果の評価2014
- Author(s)
  堀江佐知子、鈴木康弘、小林美穂、小玉哲也、佐藤靖史
- Organizer
  第13回日本超音波治療研究会（JSTU2014）
- Place of Presentation
  仙台情報・産業プラザ　多目的ホール（宮城県・仙台市）
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Distinctive roles of Vasohibin-1A and Vasohibin-1B in angiogenesis regulation2014
- Author(s)
  Sachiko Horie, Yasuhiro Suzuki, Miho Kobayashi, Yasufumi Sato
- Organizer
  第22回日本血管生物医学会学術集（併：第18回国際血管生物学会IVBM）
- Place of Presentation
  京都、京都市勧業館みやこめっせ
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] ナノ・マイクロバブルと超音波を用いたVasohibin-1遺伝子導入による抗腫瘍効果の評価2014
- Author(s)
  堀江佐知子、小林美穂、鈴木康弘、小玉哲也、佐藤靖史
- Organizer
  第26回バイオエンジニアリング講演会
- Place of Presentation
  仙台、東北大学片平さくらホール
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による微小管の翻訳後修飾を介したVEGFシグナル伝達の新規抑制機構2013
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸、神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1が誘導する微小管翻訳後修飾とVEGFシグナル伝達との関係2013
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪、千里阪急ホテル
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Role of the vasohibin family in the regulation of placental morphogenesis
- Author(s)
  Kaori Suenaga, Shuji Kitahara, Yasuhiro Suzuki, Miho Kobayashi, Sachiko Horie, Junichi Sugawara, Nobuo Yaegashi, Yasufumi Sato
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Distinctive roles of Vasohibin-1A and Vasohibin-1B in angiogenesis regulation
- Author(s)
  Sachiko Horie, Yasuhiro Suzuki, Miho Kobayashi, Yasufumi Sato
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による抗血管新生効果の作用機序
- Author(s)
  小林美穂、鈴木康弘、佐藤靖史
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Development of a novel anti-angiogenic cancer therapy targeting vasohibin-2
- Author(s)
  Takahiro Koyanagi, Yasuhiro Suzuki, Miho Kobayashi, Hiroki Miyashita, Yasushi Saga, Mitsuaki Suzuki, Yasufumi Sato
- Organizer
  The 18th International Vascular Biology Meeting 2014
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] 抗血管新生効果における Vasohibin-1A と Vasohibin-1B の役割
- Author(s)
  堀江佐知子、鈴木康弘、小林美穂、小玉哲也、佐藤靖史
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1 induces suppression of VEGF-signaling via post- translational modification of MTs.
- Author(s)
  Miho Kobayashi
- Organizer
  The 10th Vasohibin Meeting
- Place of Presentation
  ラフォーレ蔵王リゾート＆スパ（宮城県・蔵王町）
- Year and Date
  2015-01-10 – 2015-01-11
- Data Source
  KAKENHI-PROJECT-25870070
[Presentation] Vasohibin-1による抗血管新生メカニズム
- Author(s)
  小林美穂
- Organizer
  第１回血管生物若手研究会
- Place of Presentation
  東京大学医学部教育研究棟2階第1・2セミナー室（東京都）
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-25870070

1. Nakayama Masanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Graumann Johannes

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kobayashi Miho 小林 美穂

KOBAYASHI Miho 小林 美穂

Research Projects

Research Products

Co-Researchers

腫瘍の臓器向性転移における血管の役割とその分子機構Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of vascular stabilization by vasohibin-1 aimed at the establishment of anti-tumor therapy.(Fostering Joint International Research)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of vascular stabilization mechanism by anti-angiogenic factor vasohibin-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Vasohibin-1 signaling mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiangiogenic Effects of VH02, a Novel Urea Derivative: In Vitro and in Vivo Studies.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinctive role of vasohibin-1A and its splicing variant vasohibin-1B in tumor angiogenesis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation.2014

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced cancer metastasis in mice deficient in vasohibin-1 gene.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Vasohibin-1による微小管の翻訳後修飾を介した機能とその役割2019

Author(s)

Organizer

Data Source

[Presentation] Vasohibin-1による微小管の翻訳後修飾を介したVEGFシグナル伝達調節2019

Author(s)

Organizer

Data Source

[Presentation] Vasohibin-1による血管新生抑制の分子機構2019

Author(s)

Organizer

Data Source

[Presentation] 血管・リンパ管形成調節因子バソヒビン-1による血管新生抑制の分子機構2019

Author(s)

Organizer

Data Source

[Presentation] 血管新生ネガティブフィードバック因子：Vasohibin-1による微小管の翻訳後修飾を介した血管新生抑制機構2019

Author(s)

Organizer

Data Source

[Presentation] Vasohibin-1 による微小管の翻訳後修飾とその機能2019

Author(s)

Organizer

Data Source

[Presentation] The post-translational modification of microtubules mediates angiogenic signaling.2017

Author(s)

Organizer

Kobayashi Miho 小林美穂

KOBAYASHI Miho 小林美穂