KANO KUNIYUKI 可野邦行

… Alternative Names

Kano Kuniyuki 可野邦行

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Researcher Number	50636404
Other IDs
Affiliation (Current)	2026: 東京大学, 大学院薬学系研究科(薬学部), 助教
Affiliation (based on the past Project Information) *help	2026: 東京大学, 大学院薬学系研究科(薬学部), 助教 2020 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 助教 2016 – 2020: 東北大学, 薬学研究科, 助教 2012 – 2013: 東北大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 47040:Pharmacology-related / Basic Section 46030:Function of nervous system-related / Biological pharmacy / Medical pharmacy Except Principal Investigator Basic Section 52030:Psychiatry-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 44020:Developmental biology-related / Basic Section 53050:Dermatology-related / Basic Section 56030:Urology-related / Physical pharmacy
Keywords	Principal Investigator 迷走神経 / GPCR / 求心性迷走神経 / リゾリン脂質 / リゾホスファチジン酸 / DREADD / イメージングMS / 誘導体化 / MSイメージング / リン脂質代謝 … More / 質量分析イメージング / Gタンパク質共役型受容体 / 生理活性脂質 / ドコサヘキサエン酸 / 心筋梗塞 / LPA3 / 虚血性心疾患 … More Except Principal Investigator S1P / 質量分析計 / MSイメージング / MALDI / スフィンゴ脂質 / 抗うつ薬 / ドラッグリポジショニング / リゾリン脂質 / 患者層別化 / 創薬 / 層別化 / リゾフォスファチジン酸受容体１ / リゾリン脂質代謝 / LPAR1 / うつ病 / 細胞外小胞 / 脂質ラフト / リピドーム / トランスクリプトーム / 子宮内膜 / 着床 / 胚発生 / 遊走 / 脂質 / 皮膚 / ドラッグ・リポジショニング / 誘導体化 / 一細胞 / MSイメージング法 / バイオマーカー / アナンダミド / リノール酸 / 血液バイオマーカー / 膀胱痛症候群 / 間質性膀胱炎 / 肝癌 / LC-MS/MS / イメージング MS / イオンモビリティ / スフィンゴシン一リン酸 / IMS / DIUTHAME / DESI / 立体可視化 / 組織切片 / イメージングMS / 粘着性導電性フィルム / 凍結組織切片 Less

LPA時空間アトラスに基づく肺線維症におけるLPA多面的機能の解明Principal Investigator
- Principal Investigator
  
  可野邦行
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
脂質に着目した皮膚免疫細胞の遊走制御機構の解明と治療薬開発へ向けた分子基盤の構築
- Principal Investigator
  
  住田隼一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  The University of Tokyo
投影型MSイメージング法による脂質ラフト含有スフィンゴ脂質の可視化技術開発
- Principal Investigator
  
  三枝大輔
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Teikyo University
Stratification of depression based on lysophospholipid metabolic disorders and innovative development of novel antidepressants
- Principal Investigator
  
  竹林実
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kumamoto University
胚発生活性化を担保する着床期胚・子宮内膜間相互作用の解明
- Principal Investigator
  
  藍川志津
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  The University of Tokyo
求心性迷走神経に発現しているGPCRの網羅的な機能予測とその実証Principal Investigator
- Principal Investigator
  
  可野邦行
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  The University of Tokyo
Development of a novel antidepressant targeting the LPA1 receptor by drug repositioning
- Principal Investigator
  
  Kajitani Naoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kumamoto University
Uncovering a novel function of lysophospholipids through MS imaging technologyPrincipal Investigator
- Principal Investigator
  
  Kano Kuniyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Elucidation of pathophysiology and development of blood biomarkers focusing on lipid metabolism in interstitial cystitis
- Principal Investigator
  
  Torimoto Kazumasa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nara Medical University
Distribution analysis of S1P on tissue sections by high resolution MS imaging
- Principal Investigator
  
  Saigusa Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Teikyo University
  Tohoku University
Screening and profiling of GPCRs in vagal afferent nervePrincipal Investigator
- Principal Investigator
  
  Kano Kuniyuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Tohoku University
Development of tree-dimensional MS imaging for sphingolipids
- Principal Investigator
  
  Saigusa Daisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku University
The mechanism of novel LPA3-mediated activation of vagal afferent nervePrincipal Investigator
- Principal Investigator
  
  Kano Kuniyuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
New function of LPA3 receptor that regulates vagal afferent nerves activationPrincipal Investigator
- Principal Investigator
  
  KANO KUNIYUKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012

All Journal Article Presentation Book

[Book] リゾリン脂質に対する受容体, 242013
- Author(s)
  可野邦行、井上飛鳥、石黒純、青木淳賢
- Publisher
  遺伝子医学MOOK
- Data Source
  KAKENHI-PROJECT-24890014
[Journal Article] Direct activation of microglia by β-glucosylceramide causes phagoptosis of neurons that exacerbates Gaucher disease.2023
- Author(s)
  Shimizu T, Schutt C R, Izumi Y, Tomiyasu N, Omahdi Z, Kano K, Takamatsu H, Aoki J, Bamba T, Kumanogoh A, Takao M, Yamasaki S*.
- Journal Title
  
  Immunity
  
  Volume: 56 Issue: 2 Pages: 1-13
- DOI
  10.1016/j.immuni.2023.01.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18924, KAKENHI-PLANNED-22H05183, KAKENHI-PLANNED-22H05185, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-22KJ2427, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-22H00438
[Journal Article] Improving the Signal Intensity of Cryosections Using a Conductive Adhesive Film in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging2023
- Author(s)
  Saigusa Daisuke、Saito Ritsumi、Kawamoto Komei、Uruno Akira、Kano Kuniyuki、Shimma Shuichi、Aoki Junken、Yamamoto Masayuki、Kawamoto Tadafumi
- Journal Title
  
  Mass Spectrometry
  
  Volume: 12 Issue: 1 Pages: A0137-A0137
- DOI
  10.5702/massspectrometry.A0137
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2023-12-12
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] Distributions of CHN compounds in meteorites record organic syntheses in the early solar system2023
- Author(s)
  Furukawa Yoshihiro、Saigusa Daisuke、Kano Kuniyuki、Uruno Akira、Saito Ritsumi、Ito Motoo、Matsumoto Megumi、Aoki Junken、Yamamoto Masayuki、Nakamura Tomoki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-023-33595-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] Dynamic modulations of urinary sphingolipid and glycerophospholipid levels in COVID-19 and correlations with COVID-19-associated kidney injuries2022
- Author(s)
  Kurano Makoto、Jubishi Daisuke、Okamoto Koh、Hashimoto Hideki、Sakai Eri、Morita Yoshifumi、Saigusa Daisuke、Kano Kuniyuki、Aoki Junken、Harada Sohei、Okugawa Shu、Doi Kent、Moriya Kyoji、Yatomi Yutaka
- Journal Title
  
  Journal of Biomedical Science
  
  Volume: 29 Issue: 1 Pages: 1069-1087
- DOI
  10.1186/s12929-022-00880-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20H03573
[Journal Article] Changes in Lysophospholipid Components in Ulcerative Colitis and Colitis-associated Cancer2022
- Author(s)
  SONODA HIROFUMI、KITAMURA CHIEKO、KANO KUNIYUKI、ANZAI HIROYUKI、NAGAI YUZO、ABE SHINYA、YOKOYAMA YUICHIRO、ISHII HIROAKI、KISHIKAWA JUNKO、MURONO KOJI、EMOTO SHIGENOBU、SASAKI KAZUHITO、KAWAI KAZUSHIGE、NOZAWA HIROAKI、AOKI JUNKEN、ISHIHARA SOICHIRO
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 5 Pages: 2461-2468
- DOI
  10.21873/anticanres.15724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-19H03366
[Journal Article] Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation2022
- Author(s)
  N Kondo, Y Sakurai, T Takata, K Kano, K Kume, M Maeda, N Takai, S Suzuki et al.,
- Journal Title
  
  scientific reports
  
  Volume: 12 Issue: 1 Pages: 8718-8718
- DOI
  10.1038/s41598-022-12293-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03620, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-22H00438
[Journal Article] Lysophospholipid Mediators in Health and Disease2022
- Author(s)
  Kano Kuniyuki、Aoki Junken、Hla Timothy
- Journal Title
  
  Annual Review of Pathology: Mechanisms of Disease
  
  Volume: 17 Issue: 1 Pages: 459-483
- DOI
  10.1146/annurev-pathol-050420-025929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07047
[Journal Article] Lysophosphatidylcholine mediates fast decline in kidney function in diabetic kidney disease2022
- Author(s)
  Yoshioka Kentaro、Hirakawa Yosuke、Kurano Makoto、Ube Yuko、Ono Yoko、Kojima Kensuke、Iwama Taiga、Kano Kuniyuki、Hasegawa Sho、Inoue Tsuyoshi、Shimada Takashi、Aoki Junken、Yatomi Yutaka、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  Kidney International
  
  Volume: 101 Issue: 3 Pages: 510-526
- DOI
  10.1016/j.kint.2021.10.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159
[Journal Article] Modulations of bioactive lipids and their receptors in postmortem Alzheimer’s disease brains2022
- Author(s)
  Kurano Makoto、Saito Yuko、Uranbileg Baasanjav、Saigusa Daisuke、Kano Kuniyuki、Aoki Junken、Yatomi Yutaka
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 14 Pages: 1066578-1066594
- DOI
  10.3389/fnagi.2022.1066578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20H03573, KAKENHI-PROJECT-19H03366, KAKENHI-PROJECT-22H04923
[Journal Article] Quantification of threonine-containing lysophospholipids using ESI-LC-MS/MS in mouse tissues2022
- Author(s)
  Michiyo Okudaira、Kuniyuki Kano、Kumiko Makide、Daisuke Saigusa、Tomohiko Ohwada、Junken Aoki
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 6 Issue: 2 Pages: 138-148
- DOI
  10.24508/mms.2022.11.008
- ISSN
  2432-7441, 2432-745X
- Year and Date
  2022-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03374
[Journal Article] Lysophosphatidic acid receptor <sub>1/3</sub> antagonist inhibits the activation of satellite glial cells and reduces acute nociceptive responses2022
- Author(s)
  Hoshino Yoko、Okuno Toshiaki、Saigusa Daisuke、Kano Kuniyuki、Yamamoto Shota、Shindou Hideo、Aoki Junken、Uchida Kanji、Yokomizo Takehiko、Ito Nobuko
- Journal Title
  
  The FASEB Journal
  
  Volume: 36 Issue: 4
- DOI
  10.1096/fj.202101678r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-20K09190, KAKENHI-PROJECT-21K15309, KAKENHI-PROJECT-22KJ3239, KAKENHI-PROJECT-22K06888, KAKENHI-PROJECT-23K24425, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-18H02896
[Journal Article] An ATX-LPA6-Gα13-ROCK axis shapes and maintains caudal vein plexus in Zebrafish2021
- Author(s)
  Okasato R., Kano K., Kise R., Inoue A., Fukuhara S., Aoki J.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 11 Pages: 103254-103254
- DOI
  10.1016/j.isci.2021.103254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22517, KAKENHI-PROJECT-21H02665, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-21K19358
[Journal Article] Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis2021
- Author(s)
  Uranbileg Baasanjav、Ito Nobuko、Kurano Makoto、Kano Kuniyuki、Uchida Kanji、Sumitani Masahiko、Aoki Junken、Yatomi Yutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 3984-3984
- DOI
  10.1038/s41598-021-83569-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-20K09190, KAKENHI-PROJECT-18H02896
[Journal Article] Development of an On-Tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag2021
- Author(s)
  Iwama Taiga、Kano Kuniyuki、Saigusa Daisuke、Ekroos Kim、van Echten-Deckert Gerhild、Vogt Johannes、Aoki Junken
- Journal Title
  
  Analytical Chemistry
  
  Volume: 93 Issue: 8 Pages: 3867-3875
- DOI
  10.1021/acs.analchem.0c04479
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-20H03374
[Journal Article] Suppressing postcollection lysophosphatidic acid metabolism improves the precision of plasma LPA quantification2021
- Author(s)
  Kano Kuniyuki、Matsumoto Hirotaka、Kono Nozomu、Kurano Makoto、Yatomi Yutaka、Aoki Junken
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 62 Pages: 100029-100029
- DOI
  10.1016/j.jlr.2021.100029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-17H06164, KAKENHI-PROJECT-20H03380, KAKENHI-PLANNED-17H06418, KAKENHI-PUBLICLY-21H00228
[Journal Article] Reduced Cerebrospinal Fluid Levels of Lysophosphatidic Acid Docosahexaenoic Acid in Patients With Major Depressive Disorder and Schizophrenia2021
- Author(s)
  Omori Wataru、Kano Kuniyuki、Hattori Kotaro、Kajitani Naoto、Okada-Tsuchioka Mami、Boku Shuken、Kunugi Hiroshi、Aoki Junken、Takebayashi Minoru
- Journal Title
  
  International Journal of Neuropsychopharmacology
  
  Volume: 24 Issue: 12 Pages: 948-955
- DOI
  10.1093/ijnp/pyab044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02756, KAKENHI-PROJECT-21K07501
[Journal Article] Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model.2019
- Author(s)
  Uranbileg B, Ito N, Kurano M, Saigusa D, Saito R, Uruno A, Kano K, Ikeda H, Yamada Y, Sumitani M, Sekiguchi M, Aoki J, Yatomi Y.
- Journal Title
  
  Scientific reports
  
  Volume: 9 Issue: 1 Pages: 16578-16578
- DOI
  10.1038/s41598-019-52999-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K11103, KAKENHI-PROJECT-16KK0195
[Journal Article] Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection2019
- Author(s)
  Wang Jiao、Kano Kuniyuki、Saigusa Daisuke、Aoki Junken
- Journal Title
  
  Mass Spectrometry
  
  Volume: 8 Issue: 1 Pages: A0072-A0072
- DOI
  10.5702/massspectrometry.A0072
- NAID
  130007594456
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2019-02-14
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08233
[Journal Article] Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging2019
- Author(s)
  Saigusa D, Saito R, Kawamoto K, Uruno A, Kano K, Aoki J, Yamamoto M, Kawamoto T.
- Journal Title
  
  Anal Chem
  
  Volume: 91 Issue: 14 Pages: 8979-8986
- DOI
  10.1021/acs.analchem.9b01159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-16KK0195
[Journal Article] Metabolomic Analysis of Mouse Brain after a Transient Middle Cerebral Artery Occlusion by Mass Spectrometry Imaging2018
- Author(s)
  Abe T, Niizuma K, Kanoke A, Saigusa D, Saito R, Uruno A, Fujimura M, Yamamoto M, Tominaga T.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 58 Issue: 9 Pages: 384-392
- DOI
  10.2176/nmc.oa.2018-0054
- NAID
  130007484209
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233
[Journal Article] Different Origins of Lysophospholipid Mediators between Coronary and Peripheral Arteries in Acute Coronary Syndrome.2017
- Author(s)
  Kurano, M., Kano, K., Dohi, T., Matsumoto, H., Igarashi, K., Nishikawa, M., Ohkawa, R., Ikeda, H., Miyauchi, K., Daida, H., Aoki, J., and Yatomi, Y.
- Journal Title
  
  J. Lipid Res.
  
  Volume: 58 Issue: 2 Pages: 433-442
- DOI
  10.1194/jlr.p071803
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16H06236, KAKENHI-PROJECT-16K18870
[Journal Article] Autotaxin-lysophosphatidic acid-LPA3 signaling at the embryo-epithelial boundary controls decidualization pathways2017
- Author(s)
  Aikawa Shizu、Kano Kuniyuki、Inoue Asuka、Wang Jiao、Saigusa Daisuke、Nagamatsu Takeshi、Hirota Yasushi、Fujii Tomoyuki、Tsuchiya Soken、Taketomi Yoshitaka、Sugimoto Yukihiko、Murakami Makoto、Arita Makoto、Kurano Makoto、Ikeda Hitoshi、Yatomi Yutaka、Chun Jerold、Aoki Junken
- Journal Title
  
  EMBO J
  
  Volume: 36 Issue: 14 Pages: 2146-2160
- DOI
  10.15252/embj.201696290
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08233, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-16H02613, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-15H04979, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-16K15122, KAKENHI-PROJECT-16K15700, KAKENHI-PROJECT-16K15701, KAKENHI-PROJECT-26670030
[Journal Article] Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo2014
- Author(s)
  Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J
- Journal Title
  
  J. Biochem
  
  Volume: 155 Issue: 4 Pages: 235-241
- DOI
  10.1093/jb/mvt114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J05211, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-24770114, KAKENHI-PROJECT-24790064, KAKENHI-PROJECT-24890014, KAKENHI-PROJECT-25430135, KAKENHI-PROJECT-25860021, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26640064
[Presentation] DREADDシステムを用いた求心性迷走神経におけるGαシグナルの機能解析2024
- Author(s)
  中村真基、吉田尚史、可野邦行、堀野雅人、池田賢司、山田哲也、井上飛鳥、青木淳賢
- Organizer
  NEURO2024
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] LPA3シグナルによる求心性迷走神経を介した呼吸制御機構の解析2024
- Author(s)
  中村真基、可野邦行、青木淳賢
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] LPA3 signaling alters breathing patterns by activating afferent vagal nerve2024
- Author(s)
  Masaki Nakamura, Kuniyuki Kano, Masato Horino, Kenji Ikeda, Tetsuya Yamada, Junken Aoki
- Organizer
  3rd Korea-Japan Lipid Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] リゾホスファチジン酸受容体LPA3の求心性迷走神経における機能解明2024
- Author(s)
  可野邦行、中村真基、青木淳賢
- Organizer
  NEURO2024
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] 摂食・代謝制御における求心性迷走神経Gαシグナルの機能解明2024
- Author(s)
  吉田尚史、中村真基、可野邦行、井上飛鳥、青木淳賢
- Organizer
  第23回次世代を担う若手のためのファーマ・バイオフォーラム2024
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] 代謝や摂食制御における求心性迷走神経Gαシグナルの機能解明2024
- Author(s)
  吉田尚史、中村真基、可野邦行、井上飛鳥、青木淳賢
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] Serum anandamide and lipids associated with linoleic acid can distinguish interstitial cystitis and bladder pain syndrome from overactive bladder2023
- Author(s)
  Torimoto K, Ueda T, Gotoh D, Kano K, Miyake M, Nakai Y, Hori S, Morizawa Y, Onishi K, Shimizu T, Tomizawa M, Aoki J, Fujimoto K
- Organizer
  The Annual Meeting of American Urological Association 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09566
[Presentation] イオンモビリティ搭載飛行時間MSによるスフィンゴ糖脂質異性体分離分析法開発2023
- Author(s)
  井上莉那、可野邦行、福内友子、山岡法子、青木淳賢、三枝大輔
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K27316
[Presentation] DREADDシステムを用いた求心性迷走神経におけるGαシグナルの機能解析2023
- Author(s)
  中村真基、可野邦行、井上飛鳥、青木淳賢
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] LPA3 signaling alters breathing patterns by activating afferent vagal nerve2023
- Author(s)
  Masaki Nakamura, Kuniyuki Kano, Junken Aoki
- Organizer
  FASEB Summer Research Conference on Lysophospholipid
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] Lysophosphatidic acid signaling through LPA2 suppresses apoptosis of spermatogenic cells2023
- Author(s)
  Kuniyuki Kano, Takumi Sugawara, Junken Aoki
- Organizer
  FASEB Summer Research Conference on Lysophospholipid
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] Serum anandamide and lipids associated with linoleic acid can distinguish interstitial cystitis and bladder pain syndrome from overactive bladder2023
- Author(s)
  Torimoto K, Ueda T, Gotoh D, Kano K, Miyake M, Nakai Y, Hori S, Morizawa Y, Onishi K, Shimizu T, Tomizawa M, Aoki J, Fujimoto K
- Organizer
  第110回日本排尿機能学会総会
- Data Source
  KAKENHI-PROJECT-20K09566
[Presentation] DREADDシステムを用いた求心性迷走神経におけるGαシグナルの機能解析2023
- Author(s)
  中村真基、可野邦行、井上飛鳥、青木淳賢
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K06147
[Presentation] Development of Mass spectrometry techniques for peering deeper into the phospholipid diversity2022
- Author(s)
  Kuniyuki Kano, Taiga Iwama, Junken Aoki
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] Visualization of Phospholipid Metabolism Based on MS Imaging Technology2022
- Author(s)
  Kuniyuki Kano
- Organizer
  Gordon Research Conferences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] リピドミクス分析のための質量分析法の開発とその臨床応用2022
- Author(s)
  可野邦行
- Organizer
  BPCNPNPPP4 学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] Phos-tag誘導体化法による新たな質量イメージング法の開発2021
- Author(s)
  可野邦行
- Organizer
  日本電気泳動学会第72回総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] Novel MS Imaging Methods for Phospholipid Analysis2021
- Author(s)
  Kuniyuki Kano
- Organizer
  100 Minutes with ILS Imaging lipidomics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] Development of an on-tissue derivatization method for MALDI mass spectrometry imaging of bioactive lipids containing phosphate monoester using Phos-tag2021
- Author(s)
  Kuniyuki Kano
- Organizer
  2021 AOCS Annual Meeting & Expo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] リン脂質研究における新たな質量分析イメージング法の開発とその応用2021
- Author(s)
  可野邦行、岩間大河、青木淳賢
- Organizer
  第46回日本医用マススペクトル学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] リゾホスファチジン酸はLPA2受容体を介して精子形成細胞のアポトーシスを抑制する2020
- Author(s)
  可野邦行、菅原拓海、青木淳賢
- Organizer
  第62回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] リン脂質および脂質メディエーターの質量分析イメージング2020
- Author(s)
  可野邦行、岩間大河、青木淳賢
- Organizer
  フォーラム2020：衛生薬学・環境トキシコロジー
- Invited
- Data Source
  KAKENHI-PROJECT-20K07047
[Presentation] MALDI-MSI分析における導電性粘着フィルムの生体組織切片作成への有用性について2019
- Author(s)
  三枝大輔、齋藤律水、川本孔明、宇留野晃、可野邦行、青木淳賢、山本雅之、川本忠文
- Organizer
  第44回医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-17K08233
[Presentation] 迷走神経とGPCR2019
- Author(s)
  可野邦行
- Organizer
  第18回生物化学若手研究者セミナー
- Data Source
  KAKENHI-PROJECT-18K14845
[Presentation] Screening of novel G protein-coupled receptors regulating afferent vagal activity2019
- Author(s)
  Kuniyuki Kano
- Organizer
  ICBL 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14845
[Presentation] Imaging MS analysis of lysophospholipids using AP-MALDI-MS2019
- Author(s)
  Kuniyuki Kano
- Organizer
  International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14845
[Presentation] 迷走神経を制御する新規GPCRの探索2018
- Author(s)
  佐藤悠喜飛、可野邦行、菅野真由、青木淳賢
- Organizer
  第４０回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18K14845
[Presentation] 求心性迷走神経を活性化する新規GPCRの探索2018
- Author(s)
  菅野真由、可野邦行、佐藤悠喜飛、青木淳賢
- Organizer
  第57回日本薬学会東北支部会
- Data Source
  KAKENHI-PROJECT-18K14845
[Presentation] 迷走神経におけるGPCRを介した新規受容機構の解析2018
- Author(s)
  佐藤悠喜飛、可野邦行、青木淳賢
- Organizer
  第17回次世代を担う若手ファーマ・バイオフォーラム2018
- Data Source
  KAKENHI-PROJECT-18K14845
[Presentation] Lysophosphatidic acid enhances IL-10 production in a mouse LPS model2017
- Author(s)
  Jiao Wang, Kuniyuki Kano, Kyoko Satake, Junken Aoki
- Organizer
  Keystone Symposia on Lipidomics and Bioactive Lipids in Metabolism and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] Imaging MS analysis of lysophospholipids using AP-MALDI-MS2017
- Author(s)
  Kuniyuki Kano, Daisuke Saigusa and Junken Aoki
- Organizer
  Bioactive lipids conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] Preventive and alleviative effects of LPA3 signaling in a novel mouse model of acute exacerbation of idiopathic pulmonary fibrosis2017
- Author(s)
  Naoki Omae, Kuniyuki Kano, Junken Aoki
- Organizer
  FASEB Science Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] Imaging MS analysis of lysophospholipids using AP-MALDI-MS2017
- Author(s)
  Kuniyuki Kano, Daisuke Saigusa and Junken Aoki
- Organizer
  FASEB Science Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] An emerging role of DHA-containing LPA in myocardial infarction2017
- Author(s)
  Kuniyuki Kano, Junken Aoki
- Organizer
  International Conference on Lipoquality
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] Lysophosphatidic acid stimulates IL-10 production from murine peritoneal macrophage2017
- Author(s)
  Jiao Wang, Kuniyuki Kano, Junken Aoki
- Organizer
  BMB2017
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] Imaging MS analysis of lysophospholipids using AP-MALDI-MS2017
- Author(s)
  Kuniyuki Kano, Daisuke Saigusa and Junken Aoki
- Organizer
  Keystone symposia
- Place of Presentation
  California (USA)
- Year and Date
  2017-02-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] リゾリン脂質メディエーターリゾホスファチジン酸の新規迷走神経刺激因子としての機能2016
- Author(s)
  可野邦行
- Organizer
  日本薬学会東北支部若手研究者セミナー
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-16K18870
[Presentation] 迷走神経の新規制御因子としてのリゾホスファチジン酸2013
- Author(s)
  可野邦行
- Organizer
  医療系薬学若手研究者セミナー
- Place of Presentation
  仙台
- Year and Date
  2013-10-19
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] Lysophosphatidic acid in blood regulates vagal afferent nerves through LPA3 receptor2013
- Author(s)
  Junken Aoki, Kuniyuki Kano
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Niseko, Japan
- Year and Date
  2013-09-05
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] リゾホスファチジン酸受容体LPA3をターゲットとした創薬のためのハイスループットスクリーニング2013
- Author(s)
  可野邦行、濱直人、岩渕好治、青木淳賢
- Organizer
  公開シンポジウム東北からの創薬
- Place of Presentation
  仙台
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] リゾホスファチジン酸受容体 LPA3 をターゲットとした創薬のためのハイスループットスクリーニング2013
- Author(s)
  可野邦行、濱直人、岩渕好治、青木淳賢
- Organizer
  公開シンポジウム東北からの創薬
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] New function of LPA3 receptor that regulates vagal afferent nerves activation2013
- Author(s)
  可野邦行、青木淳賢
- Organizer
  日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] リゾホスファチジン酸の新規迷走神経調節機能2013
- Author(s)
  可野邦行
- Organizer
  新学術領域研究若手ワークショップ
- Place of Presentation
  鳴門
- Year and Date
  2013-07-02
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] リゾホスファチジン酸受容体LPA3の活性化は迷走神経刺激の感受性を亢進させる2012
- Author(s)
  可野邦行（代表者）、遠藤智子、濱弘太郎、新井洋由、Jerold Chun、青木淳賢
- Organizer
  第85会日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] リゾホスファチジン酸受容体LPA3の活性化は迷走神経刺激の感受性を亢進させる2012
- Author(s)
  可野邦行,遠藤智子,濱弘太郎,新井洋由,Jerold Chun,青木淳賢
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡、福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24890014
[Presentation] リゾホスファチジン酸受容体LPA3を介した迷走神経活性化作用の解析2012
- Author(s)
  可野邦行,遠藤智子,濱弘太郎,山田哲也,片桐秀樹,新井洋由,Jerold Chun,青木淳賢
- Organizer
  第78回日本生化学会東北支部会例会
- Place of Presentation
  山形、山形大学医学部
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-24890014

1. Saigusa Daisuke (90545237)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. Kajitani Naoto (60755742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 松本洋太郎 (90420041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Torimoto Kazumasa (10382293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 元池育子 (70347178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 藤本清秀 (50264867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 住田隼一 (30609706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 藍川志津 (80884577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 坂下陽彦 (60893873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 青木順 (90452424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 竹林実 (60304440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 青木淳賢 (20250219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 岩本和也 (40342753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 服部功太郎 (50415569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 朴秀賢 (60455665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 矢富裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 福原茂朋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 和泉自泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 鈴木周五

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井上剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 宇留野晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. くぬ刀浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 横溝岳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KANO KUNIYUKI 可野 邦行

Kano Kuniyuki 可野 邦行

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LPA時空間アトラスに基づく肺線維症におけるLPA多面的機能の解明Principal Investigator

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求心性迷走神経に発現しているGPCRの網羅的な機能予測とその実証Principal Investigator

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Uncovering a novel function of lysophospholipids through MS imaging technologyPrincipal Investigator

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Screening and profiling of GPCRs in vagal afferent nervePrincipal Investigator

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The mechanism of novel LPA3-mediated activation of vagal afferent nervePrincipal Investigator

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New function of LPA3 receptor that regulates vagal afferent nerves activationPrincipal Investigator

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KANO KUNIYUKI 可野邦行

Kano Kuniyuki 可野邦行