Sakamoto Takafumi 坂本隆史

Researcher Number	50641015
Other IDs	https://orcid.org/0000-0002-5803-230X
Affiliation (Current)	2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2018 – 2024: 九州大学, 大学病院, 助教 2014 – 2015: 九州大学, 大学病院, その他
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 血行動態 / 交感神経 / 急性心不全 / 心不全 / 動脈圧反射 / 大内臓神経 / 右心 / 駆出率の保たれた心不全 / 右心機能 / 圧受容器反射 … More / 駆出率の低下した心不全 / 循環平衡 / 心機能 / 自律神経制御 / 血圧制御 / circulatory equilibrium / HFpEF / pulmonary edema / hemodynamics / heart failure / baroreflex … More Except Principal Investigator 医療機器開発 / 補助循環 / 自律神経 / 心不全 / 虚血性心疾患 Less

Elucidation of integrated mechanisms and development of novel therapies for the prevention of acute exacerbations of heart failure.Principal Investigator
- Principal Investigator
  
  坂本隆史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
The development of multimodal circulatory control system for acute heart failure
- Principal Investigator
  
  朔啓太
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Investigation of the mechanisms of worsening heart failure through sympathetic activation in heart failure with preserved ejection fractionPrincipal Investigator
- Principal Investigator
  
  坂本隆史
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
Mechanism of acute heart failure exacerbation by sympathetic nerve activation and its application to treatment via sympathetic nerve deactivationPrincipal Investigator
- Principal Investigator
  
  Sakamoto Takafumi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
Investigation of the relationship of baroreflex failure and worsening heart failurePrincipal Investigator
- Principal Investigator
  
  Sakamoto Takafumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2015 2014 Other

All Journal Article Presentation Book Patent

[Book] 月刊心エコー2020
- Author(s)
  坂本　隆史
- Total Pages
  8
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18K15851
[Book] 循環器ジャーナル2020
- Author(s)
  坂本　隆史
- Total Pages
  5
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18K15851
[Book] 心不全治療薬の考え方、使い方2019
- Author(s)
  坂本　隆史
- Total Pages
  12
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-18K15851
[Book] 心不全（第2版）中ー最新の基礎・臨床研究の進歩ー2019
- Author(s)
  坂本　隆史
- Total Pages
  7
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-18K15851
[Book] Heart View2019
- Author(s)
  坂本　隆史
- Total Pages
  7
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-18K15851
[Journal Article] A Case Report2022
- Author(s)
  Unoki Takashi、Saku Keita、Kametani Motoko、Konami Yutaka、Taguchi Eiji、Sawamura Tadashi、Nakao Koichi、Sakamoto Tomohiro
- Journal Title
  
  Int. Heart J.
  
  Volume: 63 Issue: 6 Pages: 1187-1193
- DOI
  10.1536/ihj.22-237
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2022-11-30
- Language
  English
- Data Source
  KAKENHI-PROJECT-22K08222
[Journal Article] Flow Pattern of Outflow Graft is Useful for Detecting Pump Thrombosis in a Patient with Left Ventricular Assist Device2019
- Author(s)
  Sato T, Fujino T, Higo T, Ohtani K, Hiasa K, Sakamoto T, Chishaki A, Shiose A, Tsutsui H.
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 4 Pages: 994-997
- DOI
  10.1536/ihj.18-600
- NAID
  130007684164
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-07-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21724, KAKENHI-PROJECT-18K15851, KAKENHI-PROJECT-18H03083
[Journal Article] The impact of volume loading-induced low pressure baroreflex activation on arterial baroreflex-controlled sympathetic arterial pressure regulation in normal rats2018
- Author(s)
  Oga Yasuhiro、Saku Keita、Nishikawa Takuya、Kishi Takuya、Tobushi Tomoyuki、Hosokawa Kazuya、Tohyama Takeshi、Sakamoto Takafumi、Sunagawa Kenji、Tsutsui Hiroyuki
- Journal Title
  
  Physiological Reports
  
  Volume: 6 Issue: 19 Pages: e13887-e13887
- DOI
  10.14814/phy2.13887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15851, KAKENHI-PROJECT-18K15893
[Journal Article] Pulmonary arterial input impedance reflects the mechanical properties of pulmonary arterial remodeling in rats with pulmonary hypertension.2018
- Author(s)
  Nishikawa T., Saku K., Kishi T., Tohyama T., Abe K, Oga Y., Arimura T., Sakamoto T., Yoshida K., Sunagawa K., Tsutsui H.
- Journal Title
  
  Life Sci.
  
  Volume: 21 Pages: 225-232
- DOI
  10.1016/j.lfs.2018.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09591, KAKENHI-PROJECT-18K15851, KAKENHI-PROJECT-18K15893
[Journal Article] Left Ventricular Mechanical Unloading by Total Support of Impella in Myocardial Infarction Reduces Infarct Size, Preserves Left Ventricular Function, and Prevents Subsequent Heart Failure in Dogs2018
- Author(s)
  Saku Keita、Kakino Takamori、Arimura Takahiro、Sunagawa Genya、Nishikawa Takuya、Sakamoto Takafumi、Kishi Takuya、Tsutsui Hiroyuki、Sunagawa Kenji
- Journal Title
  
  Circulation: Heart Failure
  
  Volume: 11 Issue: 5
- DOI
  10.1161/circheartfailure.117.004397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15851
[Journal Article] Changes in Vascular Properties, Not Ventricular Properties, Predominantly Contribute to Baroreflex Regulation of Arterial Pressure.2015
- Author(s)
  Sakamoto T, Kakino T, Sakamoto K, Tobushi T, Tanaka A, Saku K, Hosokawa K, Onitsuka K, Murayama Y, Tsutsumi T, Ide T, Sunagawa K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 308 Issue: 1 Pages: H49-H58
- DOI
  10.1152/ajpheart.00552.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860569, KAKENHI-PROJECT-23220013
[Journal Article] Afferent vagal nerve stimulation resets baroreflex neural arc and inhibits sympathetic nerve activity.2014
- Author(s)
  Saku K, Kishi T, Sakamoto K, Hosokawa K, Sakamoto T, Murayama Y, Kakino T, Ikeda M, Ide T, Sunagawa K.
- Journal Title
  
  Physiol Rep.
  
  Volume: 2 Issue: 9 Pages: e12136-e12136
- DOI
  10.14814/phy2.12136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23220013, KAKENHI-PROJECT-26860569
[Patent] SYSTEMS AND METHODS FOR AUTONOMIC CLOSED-LOOP NEUROMODULATION IN ACHIEVING PROGRAMMABLE CONTROL OF MEAN BLOOD PRESSURE AND BLOOD PRESSURE VARIABILITY2018
- Inventor(s)
  朔啓太、砂川賢二、遠山岳誌、細川和也、坂本隆史
- Industrial Property Rights Holder
  朔啓太、砂川賢二、遠山岳誌、細川和也、坂本隆史
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] A Case of Ventricular Functional Regurgitation with Membranous Chordae visualized during the MitraClip procedure2024
- Author(s)
  Izumi Ryo, Takafumi Sakamoto, Shiose Akira, Shintaro Kinugawa
- Organizer
  第88回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] A case of acute hemodynamic responder to cardiac resynchronization therapy in a patient with atypical right bundle branch block2024
- Author(s)
  Keimei Yoshida, Takafumi Sakamoto, Tsukasa Watanabe, Kazuya Hosokawa, Shintaro Kinugawa
- Organizer
  第88回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] FMRに対するMitraClip2023
- Author(s)
  坂本隆史、柿野貴盛、吉田賢明、横山拓、稗田道成、調宗一郎、藤田一允、塩瀬明、絹川真太郎
- Organizer
  第31回日本心血管インターベンション治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 心室性機能性MRに対するトータルマネージメント2023
- Author(s)
  坂本隆史、柿野貴盛、吉田賢明、横山拓、稗田道成、調宗一郎、藤田一允、塩瀬明、絹川真太郎
- Organizer
  第13回日本経カテーテル心臓弁治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 心不全に対する交感神経ターゲットデバイス2023
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第87回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] Membranous chordによりMitraClip留置が困難であった機能性僧帽弁閉鎖不全症の一例2023
- Author(s)
  坂本隆史、吉田賢明、横山拓、絹川真太郎、木村聡、塩瀬明
- Organizer
  第13回日本経カテーテル心臓弁治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 心室性二次性僧帽弁逆流に対するMitraClip～外科手術・補助人工心臓・心臓移植とのすみわけは？～2023
- Author(s)
  坂本隆史、柿野貴盛、吉田賢明、横山拓、稗田道成、調宗一郎、藤田一允、塩瀬明、絹川真太郎
- Organizer
  第31回日本心血管インターベンション治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 包括的心不全治療の最新戦略2023
- Author(s)
  坂本隆史
- Organizer
  第27回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 効果最大化を目指す薬物療法とCRTハイブリッド戦略～CRT保険適用拡大への期待～2023
- Author(s)
  坂本隆史
- Organizer
  第44回日本循環制御医学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 右室機能低下を伴う心不全の薬物療法/非薬物療法2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第23回日本成人先天性心疾患学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 右室機能低下を伴う心不全の薬物療法/非薬物療法2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第23回日本成人先天性心疾患学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 薬物療法とCRT～双方の治療効果を最大化する治療戦略～2022
- Author(s)
  坂本隆史
- Organizer
  第26回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 第33回臨床モニター学会総会2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  肺動脈カテーテルは循環管理に必要
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 心不全治療ではポンプ機能治療こそ重要－心不全の病態生理から深読みする－2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第86回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 心不全に対する交感神経ターゲットデバイス2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第87回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 心不全に対する心房間シャント作成デバイス2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第23回日本成人先天性心疾患学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 第33回臨床モニター学会総会2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  肺動脈カテーテルは循環管理に必要
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 麻酔に活かす血行動態と循環生理2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第69回日本麻酔科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 薬物療法とCRT～双方の治療効果を最大化する治療戦略～2022
- Author(s)
  坂本隆史
- Organizer
  第26回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 麻酔に活かす血行動態と循環生理2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第69回日本麻酔科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 心不全に対する心房間シャント作成デバイス2022
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第23回日本成人先天性心疾患学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08475
[Presentation] 心血管を操る自律神経と循環制御2021
- Author(s)
  坂本隆史
- Organizer
  第41回循環制御医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 血行動態応答から考える僧帽弁閉鎖不全症に対するMitraClipの効果2021
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第32回日本心エコー図学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] Basic knowledge of PV loop and circulatory physiology for bedside heart failure treatment2021
- Author(s)
  坂本隆史
- Organizer
  第85回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 血行動態から考える僧帽弁閉鎖不全症に対するMitraClipの効果2021
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第41回循環制御医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 生体システム応答から考える急性心不全の多臓器連関と治療対象としての可能性2020
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第24回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 心不全に対する心房間シャントデバイスの現状と将来展望2020
- Author(s)
  坂本隆史、筒井裕之
- Organizer
  第24回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] Management of heart rate and rhythm in acute decompensated heart failure2019
- Author(s)
  Takafumi Sakamoto
- Organizer
  The 23rd Annual Scientific Meeting of the Japanese Heart Failure Society
- Invited
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] Maladaptive hemodynamic responses to sympathetic activation play a pivotal role in the pathogenesis of acute decompensated heart failure2019
- Author(s)
  Takafumi Sakamoto, Keita Saku, Kenji Sunagawa, Hiroyuki Tsutsui
- Organizer
  The 92th Annual Scientific Meeting of the American Heart Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15851
[Presentation] 1.重症心不全における自律神経系の意義とその治療対象としての可能性2015
- Author(s)
  坂本隆史
- Organizer
  第53回日本人工臓器学会
- Place of Presentation
  東京
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26860569
[Presentation] 2.Autonomic Regulation of the Pressure-Volume Relationship and Hemodynamics in Normal and Heart Failure2015
- Author(s)
  Sakamoto T et al
- Organizer
  37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
- Place of Presentation
  Millano
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860569
[Presentation] 4.Baroreflex activation therapy (BAT) as a novel therapeutic strategy for acute decompensated heart failure with reduced ejection fraction2015
- Author(s)
  Sakamoto T et al
- Organizer
  The 79th Annual Scientific Meeting of The Japanese Circulation Society
- Place of Presentation
  大阪
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-26860569
[Presentation] 慢性心不全に対する神経介入治療の現状と期待2015
- Author(s)
  坂本隆史
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26860569
[Presentation] Activation of baroreflex instantly reduces left atrial pressure and increases cardiac output in dogs with pacing induced heart failure
- Author(s)
  Sakamoto T, Kakino T, Saku K, Sunagawa K.
- Organizer
  第18回日本心不全学会総会
- Place of Presentation
  大阪
- Year and Date
  2014-10-10 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-26860569
[Presentation] Discordant Impact of Baroreflex Activation on Cardiac Output Between the Normal Heart and Failing Heart
- Author(s)
  Sakamoto T, Kakino T, Saku K, Sakamoto K, Sunagawa K.
- Organizer
  The 87th Annual Scientific Meeting of the American Heart Association
- Place of Presentation
  Chicago, USA,
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26860569
[Presentation] Intravascular electrical stimulation of carotid sinus activates baroreflex and decreases arterial pressure in an anesthetized dog
- Author(s)
  Sakamoto T, Saku K, Kakino T, Arimura T, Sunagawa K.
- Organizer
  第53回日本生体医工学会大会
- Place of Presentation
  仙台
- Year and Date
  2014-06-24 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26860569

1. 朔啓太 (40567385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 安在大祐 (40611116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 荒船龍彦 (50376597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KISHI Takuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 阿部弘太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 筒井裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 砂川賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 井手友美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamoto Takafumi 坂本 隆史

Research Projects

Research Products

Co-Researchers

Elucidation of integrated mechanisms and development of novel therapies for the prevention of acute exacerbations of heart failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of multimodal circulatory control system for acute heart failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the mechanisms of worsening heart failure through sympathetic activation in heart failure with preserved ejection fractionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of acute heart failure exacerbation by sympathetic nerve activation and its application to treatment via sympathetic nerve deactivationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the relationship of baroreflex failure and worsening heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 月刊心エコー2020

Author(s)

Total Pages

Publisher

Data Source

[Book] 循環器ジャーナル2020

Author(s)

Total Pages

Publisher

Data Source

[Book] 心不全治療薬の考え方、使い方2019

Author(s)

Total Pages

Publisher

Data Source

[Book] 心不全（第2版）中ー最新の基礎・臨床研究の進歩ー2019

Author(s)

Total Pages

Publisher

Data Source

[Book] Heart View2019

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] A Case Report2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Flow Pattern of Outflow Graft is Useful for Detecting Pump Thrombosis in a Patient with Left Ventricular Assist Device2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The impact of volume loading-induced low pressure baroreflex activation on arterial baroreflex-controlled sympathetic arterial pressure regulation in normal rats2018

Author(s)

Journal Title

DOI

Sakamoto Takafumi 坂本隆史

[Presentation] 右室機能低下を伴う心不全の薬物療法/非薬物療法2022

[Presentation] 右室機能低下を伴う心不全の薬物療法/非薬物療法2022