KATSUYAMA YOHEI 勝山陽平

… Alternative Names

Katsuyama Yohei 勝山陽平

KATSUYAMA Yohei 勝山陽平

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Researcher Number	50646437
Other IDs	https://orcid.org/0000-0003-4905-5320
Affiliation (Current)	2026: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help	2016 – 2025: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2013 – 2014: 東京大学, 農学生命科学研究科, 講師
Review Section/Research Field	Principal Investigator Science and Engineering / Basic Section 38040:Bioorganic chemistry-related / Applied microbiology / Basic Section 38040:Bioorganic chemistry-related / Transformative Research Areas, Section (II) / Basic Section 37010:Bio-related chemistry Except Principal Investigator Transformative Research Areas, Section (II)
Keywords	Principal Investigator 生合成 / 放線菌 / 天然物 / biosynthesis / 酵素 / 二次代謝 / ジアゾ基 / 亜硝酸 / ポリケタイド合成酵素 / polyketide … More / secondary metabolite / nonribosomal peptide / X線結晶構造解析 / 非リボソームペプチド合成酵素 / 二次代謝産物 / 非リボソームペプチド / ポリケタイド / ペプチド / クライオ電子顕微鏡 / natural products / Streptomyces / polyketide synthase / 芳香族化合物 / ポリエン / enzymes / actinobacteria / enzyme / JBIR-34 / ヘテロ環化 / 進化工学 / 微生物生産 / 合成生物学 / 指向性進化 / バイオセンサー / biosensor / directed evolution / engineering / 有機化学 / 応用微生物 … More Except Principal Investigator 情報科学 / 計算科学 / 有機合成 / 生物合成 / 天然物化学 / 国際交流 / 天然有機化合物 / 生合成 / 反応機構 / 酵素 / 生物活性物質 / 生体分子 Less

Study on the biosynthesis of polyketide alkaloids from actinobacteriaPrincipal Investigator
- Principal Investigator
  
  勝山陽平
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  The University of Tokyo
Biosynthetic study and genome mining of diazo group-containing natural productsPrincipal Investigator
- Principal Investigator
  
  勝山陽平
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  The University of Tokyo
Study on the biosynthesis of secondary metabolites with unique nitrogen-containing functional group produced by actinobacteriaPrincipal Investigator
- Principal Investigator
  
  Yohei Katsuyama
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  The University of Tokyo
予知生合成科学・研究総括班
- Principal Investigator
  
  葛山智久
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Enhancing the diversity of peptides by amino acids with reactive functional groupsPrincipal Investigator
- Principal Investigator
  
  勝山陽平
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Study on biosynthesis of thiotemplate enzymesPrincipal Investigator
- Principal Investigator
  
  勝山陽平
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Study on biosynthetic machinery of type II polyketide synthasePrincipal Investigator
- Principal Investigator
  
  Katsuyama Yohei
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  The University of Tokyo
Analysis of reaction mechanism of nonribosomal peptide synthetase.Principal Investigator
- Principal Investigator
  
  勝山陽平
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Development of method using synthetic biology to design artificial biosynthetic pathway.Principal Investigator
- Principal Investigator
  
  Katsuyama Yohei
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
ユニークな骨格を持つ放線菌由来二次代謝産物の生合成経路の解明Principal Investigator
- Principal Investigator
  
  勝山陽平
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Study on biosynthesis of natural products with diazo groupPrincipal Investigator
- Principal Investigator
  
  KATSUYAMA Yohei
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013

All Journal Article Presentation

[Journal Article] Structural Basis for the Catalytic Mechanism of ATP‐Dependent Diazotase CmaA62025
- Author(s)
  Kawai Seiji、Karasawa Masayuki、Moriwaki Yoshitaka、Terada Tohru、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: in press Issue: 27
- DOI
  10.1002/anie.202505851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-22KJ1046
[Journal Article] Identification of Two Distinct Stereoselective Lysine 5‐Hydroxylases by Genome Mining Based on Alazopeptin Biosynthetic Enzymes2025
- Author(s)
  Kawai Seiji、Moriga Kota、Nirdnoy Warawadee、Hara Ryotaro、Ogawa Jun、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 31 Issue: 20
- DOI
  10.1002/chem.202404790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-22KJ1046
[Journal Article] Identification of the p-coumaric acid biosynthetic gene cluster in Kutzneria albida: insights into the diazotization-dependent deamination pathway2024
- Author(s)
 Kawai Seiji、Yamada Akito、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
 
 Beilstein Journal of Organic Chemistry
 
 Volume: 20 Pages: 1-11
- DOI
 10.3762/bjoc.20.1
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22KJ1046, KAKENHI-PLANNED-19H05685, KAKENHI-PLANNED-22H05130
[Journal Article] Production of Phenyldiazene Derivatives Using the Biosynthetic Pathway of an Aromatic Diazo Group‐Containing Natural Product from an Actinomycete2024
- Author(s)
  Kawai Seiji、Ning Jiayu、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  ChemBioChem
  
  Volume: 26 Issue: 1
- DOI
  10.1002/cbic.202400687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-22KJ1046
[Journal Article] Identification of the cirratiomycin biosynthesis gene cluster in Streptomyces cirratus: elucidation of the biosynthetic pathways for 2,3‐diaminobutyric acid and hydroxymethylserine2024
- Author(s)
  Sakata Shunki、Li Jiafeng、Yasuno Yoko、Shinada Tetsuro、Shin‐ya Kazuo、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: - Issue: 28
- DOI
  10.1002/chem.202400271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05685, KAKENHI-PUBLICLY-23H04560, KAKENHI-PROJECT-20H02869, KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-24K08431
[Journal Article] Identification and Analysis of the Biosynthetic Gene Cluster for the Hydrazide-Containing Aryl Polyene Spinamycin2023
- Author(s)
  Kawai Seiji、Yamada Akito、Du Danyao、Sugai Yoshinori、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 18 Issue: 8 Pages: 1821-1828
- DOI
  10.1021/acschembio.3c00248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ1046, KAKENHI-PLANNED-19H05685, KAKENHI-PLANNED-22H05130
[Journal Article] In vitro characterization of nonribosomal peptide synthetase-dependent O-(2-hydrazineylideneacetyl)serine synthesis indicates a stepwise oxidation strategy to generate the α-diazo ester moiety of azaserine2023
- Author(s)
 Shikai Yusuke、Kawai Seiji、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
 
 Chemical Science
 
 Volume: 14 Issue: 33 Pages: 8766-8776
- DOI
 10.1039/d3sc01906c
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22KJ1046, KAKENHI-PLANNED-19H05685, KAKENHI-PLANNED-22H05130, KAKENHI-PROJECT-23K23459
[Journal Article] Enzymatic synthesis of non-natural flavonoids by combining geranyl pyrophosphate C6-methyltransferase and aromatic prenyltransferase2022
- Author(s)
  Tsutsumi Hayama、Urano Naoki、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 86 Issue: 9 Pages: 1270-1275
- DOI
  10.1093/bbb/zbac099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15305, KAKENHI-PLANNED-22H05130
[Journal Article] Bacterial Avenalumic Acid Biosynthesis Includes Substitution of an Aromatic Amino Group for Hydride by Nitrous Acid Dependent Diazotization2022
- Author(s)
  Kawai Seiji、Hagihara Ryota、Shin‐ya Kazuo、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 61 Issue: 45
- DOI
  10.1002/anie.202211728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ1046, KAKENHI-PLANNED-19H05685, KAKENHI-PLANNED-22H05130
[Journal Article] Complete Biosynthetic Pathway of Alazopeptin, a Tripeptide Consisting of Two Molecules of 6‐Diazo‐5‐oxo‐ l ‐norleucine and One Molecule of Alanine2021
- Author(s)
  Kawai Seiji、Sugaya Yuko、Hagihara Ryota、Tomita Hiroya、Katsuyama Yohei、Ohnishi Yasuo
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 60 Issue: 18 Pages: 10319-10325
- DOI
  10.1002/anie.202100462
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04645, KAKENHI-PLANNED-19H05685
[Journal Article] Structural and functional analyses of the tridomain‐nonribosomal peptide synthetase FmoA3 for 4‐methyloxazoline ring formation2021
- Author(s)
  Katsuyama Yohei、Sone Kaoru、Harada Ayaka、Kawai Seiji、Urano Naoki、Adachi Naruhiko、Moriya Toshio、Kawasaki Masato、Shin-ya Kazuo、Senda Toshiya、Ohnishi Yasuo
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 未定 Issue: 26 Pages: 14554-14562
- DOI
  10.1002/anie.202102760
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04645, KAKENHI-PROJECT-19H03197
[Journal Article] Recent Advance in the Biosynthesis of Nitrogen-Nitrogen Bond-Containing Natural Products2020
- Author(s)
  Yohei Katsuyama, Kenichi Matsuda
- Journal Title
  
  Current opinion in Chemical Biology
  
  Volume: 59 Pages: 62-68
- DOI
  10.1016/j.cbpa.2020.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H04645, KAKENHI-PROJECT-19K16390
[Journal Article] Structural basis for selectivity in a highly reducing type II polyketide synthase.2020
- Author(s)
  Danyao Du, Yohei Katsuyama, Masanobu Horiuchi, Shinya Fushinobu, Aochiu Chen, Tony D. Davis, Michael D. Burkart, Yasuo Ohnishi
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 未定 Issue: 7 Pages: 776-782
- DOI
  10.1038/s41589-020-0530-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02144
[Journal Article] Involvement of β‐Alkylation Machinery and Two Sets of Ketosynthase‐Chain‐Length Factors in the Biosynthesis of Fogacin Polyketides in Actinoplanes missouriensis2019
- Author(s)
  Sato Kei、Katsuyama Yohei、Yokota Kousuke、Awakawa Takayoshi、Tezuka Takeaki、Ohnishi Yasuo
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 8 Pages: 1039-1050
- DOI
  10.1002/cbic.201800640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0095, KAKENHI-PROJECT-18H02144, KAKENHI-PROJECT-17H04763
[Journal Article] Biosynthesis of the 4-methyloxazoline-containing nonribosomal peptides, JBIR-34 and -35, in Streptomyces sp. Sp080513GE-23.2014
- Author(s)
  Adeline Muliandi, Yohei Katsuyama, Kaoru Sone, Miho Izumikawa, Tomohiro Moriya, Junko Hashimoto, Ikuko Kozone, Motoki Takagi, Kazuo Shin-ya, Yasuo Ohnishi.
- Journal Title
  
  Chemistry and Biology
  
  Volume: 21 Issue: 8 Pages: 923-934
- DOI
  10.1016/j.chembiol.2014.06.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25108706
[Presentation] 芳香族ポリケタイドyoropyrazoneにおけるスピロ環骨格形成までの生合成経路の解析2025
- Author(s)
  道下ひかる、清藤鈴奈、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度大会、札幌
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Azaserine生合成由来ヘテロ環化ドメインが触媒するエステル結合形成反応の構造基盤2025
- Author(s)
  四海佑亮、唐澤昌之、森脇由隆、寺田透、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度　札幌大会
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] Microbispora corallina由来ATP依存型ジアゾ化酵素のクライオ電子顕微鏡単粒子構造解析2025
- Author(s)
  寧嘉宇、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度大会、札幌
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Streptazone生合成に関与する新規5員環形成酵素の構造機能解析2025
- Author(s)
  山田健登、平松太地、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度大会、札幌
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] ATP依存型ジアゾ化酵素CmaA6の反応機構の解明2025
- Author(s)
  川合誠司、唐澤昌之、森脇由隆、寺田透、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度大会、札幌
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Longispora sp. K20-0274が持つアリールポリエン生合成遺伝子クラスターの機能解析2025
- Author(s)
  松浦由佳、菊池雄太、堤隼馬、稲橋佑起、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度大会、札幌
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Spinamycin生合成におけるヒドラジド形成機構の解析2025
- Author(s)
  川合誠司、森賀嵩太、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2025年度大会、札幌
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] AZASERINE BIOSYNTHESIS IN STREPTOMYCES FRAGILIS2025
- Author(s)
  Shikai Yusuke, Seiji Kawai, Yohei Katsuyama ,Yasuo Ohnishi
- Organizer
  International Conference on Natural Product Discovery and Development in the Genomic Era（San Diego, USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] Streptomyces 由来ポリケタイド streptazone 類の生合成に関する研究2024
- Author(s)
  山田健登、平松太地、勝山陽平、大西康夫
- Organizer
  第38回（2024年度）日本放線菌学会大会（一橋講堂）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Diversity of diazo group biosynthesis in actinobacteria2024
- Author(s)
  Yohei Katsuyama
- Organizer
  The 2nd Taiwan-Japan Bilateral Symposium on Natural Products Biosynthesis, Tokyo, November 14-15
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Diversity of Diazo Group Biosynthesis in Actinobacteria2024
- Author(s)
  Yohei Katsuyama
- Organizer
  3rd Japanese-German Symposium on the Biosynthesis of Natural Products, Bonn, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Streptomyces yatensis 由来 ANS 経路遺伝子含有天然物生合成遺伝子ラスターのゲノムマイニング2024
- Author(s)
  河野由幸、勝山陽平、大西康夫
- Organizer
  第38回（2024年度）日本放線菌学会大会（一橋講堂）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Diversity of diazo group biosynthesis in actinobacteria2024
- Author(s)
  Yohei Katsuyama
- Organizer
  The 2nd Taiwan-Japan Bilateral Symposium on Natural Products Biosynthesis
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] 放線菌二次代謝における亜硝酸を用いた芳香環アミノ化酵素の機能解析2024
- Author(s)
  桑原康、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2024年度　東京大会
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] Streptomyces由来cyclopenta[b]pyridine含有ポリケタイドstreptazone類生合成のin vitro解析2024
- Author(s)
  平松太地、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2024年度　東京大会
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] 希少放線菌を対象としたゲノムマイニングによる新規天然物探索2024
- Author(s)
  松浦由佳、堤隼馬、稲橋佑起、勝山陽平、大西康夫
- Organizer
  第38回（2024年度）日本放線菌学会大会（一橋講堂）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Mining the novel enzymatic chemistry in the secondary metabolism of actinobacteria2024
- Author(s)
  Yohei Katsuyama
- Organizer
  The 1st Japan-Korea Actinomycetes Symposium（Korea）
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] データーベースからのATP依存型ジアゾ化酵素の探索及び基質特異性評価2024
- Author(s)
  寧嘉宇、川合誠司、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2024年度　東京大会
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Understanding the biosynthetic machineries of diazo group-containing natural products2024
- Author(s)
  Yohei Katsuyama
- Organizer
  U.S./Japan Seminar on Natural Product Biosynthesis-Enzymology, Structural Biology, Drug Discovery, and Genome Mining, Karuizawa
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Alazopeptin生合成由来N-acetyl-6-diazo-5-oxo-L-norleucine認識アデニル化酵素AzpCの基質特異性の改変2024
- Author(s)
  丸山崇史、三宅恒輝、川合誠司、森脇由隆、寺田透、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2024年度　東京大会
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Mining the novel enzymatic chemistry in the secondary metabolism of actinobacteria2024
- Author(s)
  Yohei Katsuyama
- Organizer
  The 1st Japan-Korea Actinomycetes Symposium (Korea), Seoul
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Diversity of Diazo Group Biosynthesis in Actinobacteria2024
- Author(s)
  Yohei Katsuyama
- Organizer
  3rd Japanese-German Symposium on the Biosynthesis of Natural Products（Bonn, Germany）
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] ジアゾ基含有アミノ酸azaserineの生合成経路のin vitro解析2024
- Author(s)
  四海佑亮、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2024年度　東京大会
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] 高還元型 II 型 PKS システムにおける新奇 thioesterase の同定と機能解析2024
- Author(s)
  川合誠司、勝山陽平、大西康夫
- Organizer
  第38回（2024年度）日本放線菌学会大会（一橋講堂）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Avenalumic acid biosynthesis includes substitution of an aromatic amino group for hydride via nitrous acid dependent diazotization in Streptomyces sp. RI-772023
- Author(s)
  Seiji Kawai, Kazuo Shin-ya, Yohei Katsuyama, Yasuo Ohnishi
- Organizer
  Society for Industrial Microbiology and Biotechnology (SIMB)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] 芳香族ポリケタイドyoropyrazone のスピロ環骨格形成に至るまでの生合成経路の解明2023
- Author(s)
  清藤鈴奈、勝山陽平、大西康夫
- Organizer
  2023年度（第37回）日本放線菌学会（広島県東広島市）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Production of phenyldiazene derivatives using the biosynthetic pathway of an aromatic diazo group-containing natural product from an actinomycete2023
- Author(s)
  川合誠司、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2023年度　広島大会（オンライン開催）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] ジアゾ基含有天然物生合成機構の理解と応用2023
- Author(s)
  勝山陽平
- Organizer
  日本農芸化学会2023年度　広島大会（オンライン開催）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Biosynthesis of Diazo Group-Containing Natural Products in Actinobacteria2023
- Author(s)
  Yohei Katsuyama
- Organizer
  KMB 50th Anniversary 2023 Annual Meeting & International Symposium（Gyeongju, Korea）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Alazopeptin生合成由来アデニル化酵素AzpCの基質認識の改変2023
- Author(s)
  丸⼭ 崇史、三宅恒輝、川合誠司、森脇由隆、寺田透、勝山陽平、大西康夫
- Organizer
  2023年度（第37回）日本放線菌学会（広島県東広島市）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] 放線菌における亜硝酸を用いた芳香環アミノ化機構に関する研究2023
- Author(s)
  桑原康、勝山陽平、大西康夫
- Organizer
  2022年度 (第36回) 日本放線菌学会（福井県福井市）
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] ATP依存型ジアゾ化酵素CmaA6の構造機能解析2023
- Author(s)
  川合誠司、勝山陽平、大西康夫
- Organizer
  2023年度（第37回）日本放線菌学会（広島県東広島市）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Streptomyces 由来ポリケタイドstreptazone類の生合成に関する研究2023
- Author(s)
  平松太地、勝山陽平、大西康夫
- Organizer
  2023年度（第37回）日本放線菌学会（広島県東広島市）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Biosynthesis of diazo group-containing natural products in actinobacteria2023
- Author(s)
  Yohei Katsuyama
- Organizer
  Japan-German Joint Symposium on Natural Product Biosynthesis（Kyoto）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Biosynthesis of Diazo Group-Containing Natural Products in Actinobacteria2023
- Author(s)
  Yohei Katsuyama
- Organizer
  KMB 50th Anniversary 2023 Annual Meeting & International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] Streptomyces fragilis が生産するジアゾ基含有アミノ酸azaserineの生合成機構解析2023
- Author(s)
  四海佑亮、川合誠司、勝山陽平、大西康夫
- Organizer
  2022年度 (第36回) 日本放線菌学会（福井県福井市）
- Data Source
  KAKENHI-PROJECT-23K23459
[Presentation] Biosynthesis of secondary metabolites using nitrous acid in actinobacteria2022
- Author(s)
  勝山陽平
- Organizer
  札幌生合成国際シンポジウム（北海道大学薬学部＆オンライン）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] Streptomyces cirratus が生産する非リボソームペプチドcirratiomycinの生合成研究2022
- Author(s)
  阪田峻基、李佳鳳、新家一男、品田哲郎、勝山陽平、大西康夫
- Organizer
  2022年度 (第36回) 日本放線菌学会（福井県福井市）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] 芳香族ポリケタイドyoropyrazone のスピロ環形成機構のin vitro 解析2022
- Author(s)
  清藤鈴奈、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2022年度　京都大会
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] iminimycin生合成に関わるI 型ポリケタイド合成酵素ImiA1 のアシルトランスフェラーゼドメインの基質特異性解析2022
- Author(s)
  清藤鈴奈、堤隼馬、勝山陽平、大西康夫
- Organizer
  2022年度 (第36回) 日本放線菌学会（福井県福井市）
- Data Source
  KAKENHI-PLANNED-22H05130
[Presentation] 放線菌の持つ窒素酸化物を利用した二次代謝の多様性2022
- Author(s)
  勝山陽平
- Organizer
  第95回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] In vitro解析とX線結晶構造解析による２種のII型PKSとFASにおけるACP-KS間特異性制御機構の解明2021
- Author(s)
  堀内真展, 杜丹ヤオ, DAVIS Tony D., BURKART Michael D., 勝山陽平, 大西康夫
- Organizer
  日本農芸化学会2021年度　仙台大会
- Data Source
  KAKENHI-PUBLICLY-19H04645
[Presentation] JBIR-34,35の生合成に関わるNRPSのクライオ電子顕微鏡による解析2020
- Author(s)
  浦野直樹、勝山陽平、安達成彦、川崎政人、千田俊哉、大西康夫
- Organizer
  日本農芸化学会2020年度　福岡大会
- Data Source
  KAKENHI-PUBLICLY-19H04645
[Presentation] 2つのII型PKSとFAS間におけるACPのクロストークに関するin vitro解析2020
- Author(s)
  ○堀内真展、杜丹ヤオ、勝山陽平、Burkart, Michael D.、大西康夫
- Organizer
  日本農芸化学会2020年度　福岡大会
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] Structural and biochemical analyses of methyloxazoline-forming tridomain-nonribosomal peptide synthetase2020
- Author(s)
  Yohei Katsuyama
- Organizer
  The 5th A3 foresight symposium on Chemical & Synthetic Biology of Natural Products
- Data Source
  KAKENHI-PUBLICLY-19H04645
[Presentation] ベンザスタチン生合成においてニトレン中間体を介した環化反応を触媒するP450のX線結晶構造解析2020
- Author(s)
  堤隼馬、浦野直樹、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2020年度　福岡大会
- Data Source
  KAKENHI-PUBLICLY-19H04645
[Presentation] 放線菌が生産するジアゾ基含有トリペプチドalazopeptinの全生合成経路の解明2020
- Author(s)
  川合誠司、勝山陽平、菅谷優子、冨田宏矢、大西康夫
- Organizer
  日本農芸化学会関東支部2020年度大会
- Data Source
  KAKENHI-PUBLICLY-19H04645
[Presentation] 非リボソームペプチドcirratiomycinの生合成研究2020
- Author(s)
  ○李佳鳳、曽根薫、新家一男、勝山陽平、大西康夫
- Organizer
  日本農芸化学会2020年度　福岡大会
- Data Source
  KAKENHI-PUBLICLY-19H04645
[Presentation] JBIR-34, -35とJBIR-126の生合成に関わるNRPSのモジュール間相互作用2019
- Author(s)
  角田毅、勝山陽平、新家一男、大西康夫
- Organizer
  日本農芸化学会2019年度　東京大会
- Data Source
  KAKENHI-PUBLICLY-17H05432
[Presentation] 高還元型II型PKS由来KS-CLFヘテロダイマー及びACP-KS-CLF三者複合体のX線結晶構造解析2019
- Author(s)
  杜丹ヤオ、勝山陽平、伏信進矢、Chen Aochiu、Davis Tony D、Burkart Michael、大西康夫
- Organizer
  日本農芸化学会2019年度　東京大会
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] 放線菌の持つ二次代謝経路の探索と機能解析2019
- Author(s)
  勝山　陽平
- Organizer
  第18回微生物研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] Modification of Ligand Specificity of XylS through Directed Evolution.2018
- Author(s)
  Yohei Katsuyama, ○Yuki Ogawa, Kento Ueno and Yasuo Ohnishi
- Organizer
  18th International Symposium on the Biology of Actinomycetes (International Convention Center JEJU)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14880
[Presentation] JBIR-34, -35の生合成を担う非リボソームペプチド合成酵素FmoA3のX線結晶構造解析2018
- Author(s)
  曽根薫、原田彩佳、勝山陽平、千田美紀、新家一男、千田俊哉、大西康夫
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PUBLICLY-17H05432
[Presentation] 放線菌の持つ多様な二次代謝産物の生合成機構2018
- Author(s)
  勝山　陽平
- Organizer
  第五回天然物化学研究会東京農業大学世田谷キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] 放線菌のもつ多様な二次代謝産物生合成機構の解析2018
- Author(s)
  勝山　陽平
- Organizer
  第3回関東支部例会　東京大学農学部弥生講堂一条ホール日本農芸化学会奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] Streptomyces sp. IFM11307 由来芳香族ポリケタイド yoropyrazone 生合成に関する研究2018
- Author(s)
  藤田夏澄, 勝山陽平, 當銘一文, 石橋正己, 大西康夫
- Organizer
  第３３回 (2018年度) 日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] Reconstitution of a Type II Polyketide Synthase Catalyzing Polyene Formation2018
- Author(s)
  Danyao Du, Yohei Katsuyama, Kazuo Shin-ya, Yasuo Ohnishi
- Organizer
  3rd European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02144
[Presentation] 放線菌の持つ多様な二次代謝産物の生合成機構2018
- Author(s)
  勝山　陽平
- Organizer
  第五回天然物化学研究会東京農業大学世田谷キャンパス
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05432
[Presentation] 放線菌のもつ多様な二次代謝産物生合成機構の解析2018
- Author(s)
  勝山　陽平
- Organizer
  第3回関東支部例会　東京大学農学部弥生講堂一条ホール日本農芸化学会奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05432
[Presentation] In vitro analysis of the biosynthesis of 4-methyloxazoline-containing nonribosomal peptides, JBIR-34 and -352017
- Author(s)
  Kaoru Sone, Ayaka Harada, Miki Senda, Toshiya Senda, Kazuo Shin-ya, Yohei Katsuyama and Yasuo Ohnishi
- Organizer
  SIMB Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05432
[Presentation] 指向性進化による転写因子XylSのリガンド認識能の改変2017
- Author(s)
  勝山陽平、○小川友希、上野堅登、大西康夫
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学 (京都)
- Data Source
  KAKENHI-PROJECT-16K14880
[Presentation] Biosynthesis of JBIR-76 and -77, aromatic polyketides with isofuranonaphthoquinone scaffold2015
- Author(s)
  Yohei Katsuyama, Kaoru Sone, Ryutaro Satou, Miho Izumikawa, Motoki Takagi, Kazuo Shin-ya, Yasuo Ohnishi
- Organizer
  Natural Product - Discovery & Development in the Post Genomic Era
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-01-12
- Data Source
  KAKENHI-PUBLICLY-25108706
[Presentation] Streptomyces sp. JE-08由来シクロペンタ[b]ピリジン環構造を有するポリケタイドJBIR-70の生合成2015
- Author(s)
  太島有香、勝山陽平、泉川美穂、大野翔登、荒川孝俊、伏信進矢、新家一男、大西康夫
- Organizer
  日本農芸化学会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PUBLICLY-25108706
[Presentation] Cremeomycinのジアゾ基形成に関与する新規亜硝酸生合成経路2015
- Author(s)
  菅井佳宣、勝山陽平、大西康夫
- Organizer
  日本農芸化学会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25850048
[Presentation] Streptomyces cremeusにおけるcremeomycin生合成に関与する新規亜硝酸脱離酵素CreGのX線結晶構造解析2015
- Author(s)
  勝山陽平、東山洋輔、佐藤優花里、菅井佳宣、千田美紀、千田俊哉、大西康夫
- Organizer
  日本農芸化学会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25850048
[Presentation] 放線菌由来4-メチルオキサゾリン環を有する非リボソームペプチドJBIR-34, 35の生合成経路のin vitro解析2014
- Author(s)
  曽根薫、勝山陽平、新家一男、大西康夫
- Organizer
  日本放線菌学会
- Place of Presentation
  つくばカピオ
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PUBLICLY-25108706
[Presentation] Cremeomycin生合成経路の解析2014
- Author(s)
  菅井佳宣、勝山陽平、大西康夫
- Organizer
  日本放線菌学会
- Place of Presentation
  筑波
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-25850048
[Presentation] 特異なヘテロ環を持つペプチドの生合成2014
- Author(s)
  勝山陽平、大西康夫
- Organizer
  日本農芸化学会関東支部2014年度第1回例会
- Place of Presentation
  東京大学
- Year and Date
  2014-05-24
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108706
[Presentation] 非リボソームペプチドJBIR-34, JBIR-35の生合成2013
- Author(s)
  勝山陽平, アデリンムリアンディ, 曽根薫, 泉川美穂, 守屋智博, 小曽根郁子, 橋本絢子, 高木基樹, 新家一男, 大西康夫
- Organizer
  放線菌学会
- Place of Presentation
  メルパルク広島
- Data Source
  KAKENHI-PUBLICLY-25108706
[Presentation] ジアゾ基含有化合物cremeomycinの生合成研究2013
- Author(s)
  菅井佳宣、勝山陽平、大西康夫
- Organizer
  放線菌学会
- Place of Presentation
  メルパルク広島
- Data Source
  KAKENHI-PROJECT-25850048
[Presentation] Biosynthesis of JBIR-34,35, nonribosomal peptides containing unusual methyloxazoline group2013
- Author(s)
  Yohei Katsuyama, Adeline Muliandi, Miho Izumikawa, Tomohiro Moriya, Ikuko Kozone, Junko Hashimoto, Motoki Takagi, Kazuo Shin-ya, Yasuo Ohnishi
- Organizer
  1st European Conference on Natural Products
- Place of Presentation
  DECHEMA-HAUS, FRANKFURT AM MAIN
- Data Source
  KAKENHI-PUBLICLY-25108706

1. 葛山智久 (30280952)

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2. 内山真伸 (00271916)

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3. 丸山千登勢 (20452120)

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4. 寺田透 (40359641)

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5. 渡辺賢二 (50360938)

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6. 山崎真巳 (70222370)

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7. 脇本敏幸 (70363900)

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8. 大栗博毅 (80311546)

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9. 淡川孝義 (80609834)

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10. 荘司長三 (90379587)

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11. 小笠原泰志 (20732986)

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12. ZHAO YONGWEI

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13. 堤隼馬

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14. 大西康夫

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KATSUYAMA YOHEI 勝山 陽平

Katsuyama Yohei 勝山 陽平

KATSUYAMA Yohei 勝山 陽平

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Co-Researchers

Study on the biosynthesis of polyketide alkaloids from actinobacteriaPrincipal Investigator

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Biosynthetic study and genome mining of diazo group-containing natural productsPrincipal Investigator

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Study on the biosynthesis of secondary metabolites with unique nitrogen-containing functional group produced by actinobacteriaPrincipal Investigator

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予知生合成科学・研究総括班

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Enhancing the diversity of peptides by amino acids with reactive functional groupsPrincipal Investigator

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Study on biosynthesis of thiotemplate enzymesPrincipal Investigator

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Study on biosynthetic machinery of type II polyketide synthasePrincipal Investigator

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Analysis of reaction mechanism of nonribosomal peptide synthetase.Principal Investigator

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Development of method using synthetic biology to design artificial biosynthetic pathway.Principal Investigator

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ユニークな骨格を持つ放線菌由来二次代謝産物の生合成経路の解明Principal Investigator

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Study on biosynthesis of natural products with diazo groupPrincipal Investigator

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[Journal Article] Structural Basis for the Catalytic Mechanism of ATP‐Dependent Diazotase CmaA62025

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[Journal Article] Identification of Two Distinct Stereoselective Lysine 5‐Hydroxylases by Genome Mining Based on Alazopeptin Biosynthetic Enzymes2025

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KATSUYAMA YOHEI 勝山陽平

Katsuyama Yohei 勝山陽平

KATSUYAMA Yohei 勝山陽平