ONISHI YASUO 大西康央

Researcher Number	50707122
Affiliation (based on the past Project Information) *help	2018: 神戸大学, 医学部附属病院, その他 2013 – 2016: 神戸大学, 医学部附属病院, 医員 2014: 神戸大学, 医学部附属病院, その他
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 炭酸ガス / HIF-1α / 低酸素環境 / 骨転移 / 乳癌 / 炭酸ガス経皮吸収 Except Principal Investigator 低酸素環境 / 肉腫幹細胞 / 炭酸ガス経皮治療 / 腫瘍内低酸素環境 … More / 炭酸ガス経皮投与 / ミトコンドリア機能 / 幹細胞 / 未分化能 / 骨軟部肉腫 / トランスレーショナルリサーチ / 臨床 / 肉腫 / 二酸化炭素 / 動物実験 / 臨床研究 / 化学療法 / トランスレーショナルリサーチ / 癌 Less

Anti-tumorigenic effects of transcutaneous carbon dioxide application on bone, soft tissue, and metastatic tumors.
- Principal Investigator
  
  Akisue Toshihiro
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kobe University
Antitumor effects of transcutaneous carbon dioxide therapy on stemness in bone and soft tissue sarcomas
- Principal Investigator
  
  KAWAMOTO Teruya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kobe University
Development of local control treatment for bone metastasis of breast cancer using transcutaneous carbon dioxide therapyPrincipal Investigator
- Principal Investigator
  
  ONISHI YASUO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kobe University

All 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway.2017
- Author(s)
  Morishita M, Kawamoto T, Hara H, Onishi Y, Ueha T, Minoda M, Katayama E Takemori T, Fukase N, Kurosaka M, Kuroda R, Akisue T
- Journal Title
  
  Int J Oncol
  
  Volume: 50 Issue: 1 Pages: 23-30
- DOI
  10.3892/ijo.2016.3775
- NAID
  120005970760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293337, KAKENHI-PROJECT-26462265
[Journal Article] Reconstruction of the Midfoot Using a Free Vascularized Fibular Graft After En Bloc Excision for Giant Cell Tumor of the Tarsal Bones: A Case Report.2016
- Author(s)
  Hara H, Kawamoto T, Onishi Y, Fujioka H, Nishida K, Kuroda R, Kurosaka M, Akisue T.
- Journal Title
  
  J Foot Ankle Surg
  
  Volume: 55 Issue: 4 Pages: 838-841
- DOI
  10.1053/j.jfas.2015.04.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-26462265
[Journal Article] Antitumor effect of YM155, a novel small-molecule survivin suppressant, via mitochondrial apoptosis in human MFH/UPS.2015
- Author(s)
  Minoda M, Kawamoto T, Ueha T, Kamata E, Morishita M, Harada R, Toda M, Onishi Y, Hara H, Kurosaka M, Akisue T.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 47(3) Issue: 3 Pages: 891-899
- DOI
  10.3892/ijo.2015.3077
- NAID
  120005970759
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462265
[Presentation] Survivin抑制薬"YM155"は骨肉腫細胞において腫瘍増殖を抑制する2015
- Author(s)
  蓑田正也、河本旭哉、上羽岳志、原仁美、大西康央、森下雅之、蒲田悦子、黒坂昌弘、秋末敏宏
- Organizer
  第48回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  日本（香川）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26462265
[Presentation] 悪性腫瘍の炭酸ガス経皮吸収の感受性の差異の検討2015
- Author(s)
  上羽岳志, 酒井良忠, 河本旭哉, 大西康央, 原田理沙, 蓑田正也, 戸田光紀, 原仁美, 黒坂昌弘, 秋末敏宏
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場(富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26293337
[Presentation] 骨・軟部腫瘍　希少疾患に光明をもたらす夢の実現へ -悪性骨・軟部腫瘍に対する炭酸ガス経皮投与療法-
- Author(s)
  秋末敏宏、大西康央、原田理沙、河本旭哉、上羽岳志、原仁美、戸田光紀、蓑田正也、森下雅之、黒坂昌弘
- Organizer
  第87回日本整形外科学会学術総会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26293337
[Presentation] 炭酸ガス経皮投与は骨・軟部肉腫におけるiPS関連遺伝子の発現を低下させる
- Author(s)
  原田理沙, 河本旭哉, 上羽岳志, 森下雅之, 蓑田正也, 戸田光紀, 大西康央, 原仁美, 酒井良忠, 黒坂昌弘, 秋末敏宏
- Organizer
  第87回日本整形外科学会学術総会
- Place of Presentation
  神戸，日本
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26462265
[Presentation] 炭酸ガス経皮投与は乳癌骨転移による骨破壊を抑制する
- Author(s)
  戸田光紀、河本旭哉、上羽岳志、原仁美、大西康央、原田理沙、蓑田正也、森下雅之、酒井良忠、井口哲弘、黒坂昌弘、秋末敏宏
- Organizer
  第８７回日本整形外科学会学術総会
- Place of Presentation
  神戸，日本
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-25893132
[Presentation] 炭酸ガス経皮投与による低酸素環境の改善は悪性線維性組織球腫のiPS関連遺伝子の発現を低下させる
- Author(s)
  原田理沙, 河本旭哉, 上羽岳志, 森下雅之, 蓑田正也, 戸田光紀, 大西康央, 原仁美, 酒井良忠, 黒坂昌弘, 秋末敏宏
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島，日本
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26462265

1. Akisue Toshihiro (90379363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. KAWAMOTO Teruya (30420558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 原仁美 (40437489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 深瀬直政 (60579324)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 新倉隆宏 (40448171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 李相亮 (40533732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. MINODA Masaya

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. MORISHITA Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. HARADA Risa

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. TAKEMORI Toshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAMATA Etsuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 小田義直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 西田佳弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ONISHI YASUO 大西 康央

Research Projects

Research Products

Co-Researchers

Anti-tumorigenic effects of transcutaneous carbon dioxide application on bone, soft tissue, and metastatic tumors.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antitumor effects of transcutaneous carbon dioxide therapy on stemness in bone and soft tissue sarcomas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of local control treatment for bone metastasis of breast cancer using transcutaneous carbon dioxide therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Reconstruction of the Midfoot Using a Free Vascularized Fibular Graft After En Bloc Excision for Giant Cell Tumor of the Tarsal Bones: A Case Report.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antitumor effect of YM155, a novel small-molecule survivin suppressant, via mitochondrial apoptosis in human MFH/UPS.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Survivin抑制薬"YM155"は骨肉腫細胞において腫瘍増殖を抑制する2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 悪性腫瘍の炭酸ガス経皮吸収の感受性の差異の検討2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 骨・軟部腫瘍 希少疾患に光明をもたらす夢の実現へ -悪性骨・軟部腫瘍に対する炭酸ガス経皮投与療法-

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 炭酸ガス経皮投与は骨・軟部肉腫におけるiPS関連遺伝子の発現を低下させる

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 炭酸ガス経皮投与は乳癌骨転移による骨破壊を抑制する

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 炭酸ガス経皮投与による低酸素環境の改善は悪性線維性組織球腫のiPS関連遺伝子の発現を低下させる

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

ONISHI YASUO 大西康央

[Presentation] 骨・軟部腫瘍　希少疾患に光明をもたらす夢の実現へ -悪性骨・軟部腫瘍に対する炭酸ガス経皮投与療法-