Yanagihara Hiromi 柳原啓見

Researcher Number	50719474
Other IDs
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 学振特別研究員 2025: 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所放射線影響研究部, 研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 学振特別研究員 2021: 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所放射線影響研究部, 研究員 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線影響研究部, 研究員(任常) 2017 – 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線影響研究部, 博士研究員(任常) 2015 – 2017: 広島大学, 原爆放射線医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Risk sciences of radiation and chemicals Except Principal Investigator Medical genome science / Pathological medical chemistry / General anatomy (including histology/embryology)
Keywords	Principal Investigator 被爆時年齢依存性 / Minマウス / 消化管腫瘍 / 低線量(率)放射線 / Apc Min/+マウス / Apc Min/+ マウス / LMD / 放射線変異シグネチャー / Apc Minマウス / 放射線発がん … More / 低線量率放射線 / NBS1 / SNP / ゲノム編集 … More Except Principal Investigator 遺伝病 / 細胞周期チェックポイント / 染色体 / モデル動物 / モデル生物 / 細胞老化 / 繊毛病 Less

量子センサ技術と機械学習による放射線影響評価の新しいアプローチPrincipal Investigator
- Principal Investigator
  
  柳原啓見
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Institutes for Quantum Science and Technology
An evaluation of the effects of low-dose and low-dose-rate exposure on intestinal tumors by radiation mutation signaturesPrincipal Investigator
- Principal Investigator
  
  YANAGIHARA Hiromi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Institutes for Quantum Science and Technology
モデル生物を用いた放射線感受性候補SNPの検証Principal Investigator
- Principal Investigator
  
  柳原啓見
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
Molecular basis underlying ciliopathy in 13 trisomy syndrome
- Principal Investigator
  
  Miyamoto Tatsuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Hiroshima University
Telomere function in premature aging phenotypes of BubR1 deficiency
- Principal Investigator
  
  MATSUURA SHINYA
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
The establishment and its application of the evaluation system of disease-associated SNP using a reverse genetics techniquePrincipal Investigator
- Principal Investigator
  
  Yanagihara Hiromi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Hiroshima University
Rescue of 21 trisomy in Down syndrome cells using spindle assembly checkpoint
- Principal Investigator
  
  Matsuura Shinya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  Hiroshima University

All 2019 2018 2016 2015

All Journal Article Presentation Book

[Book] 日本臨牀 73/ 増刊6 家族性腫瘍学2015
- Author(s)
  加藤晃弘、柳原啓見、小松賢志
- Total Pages
  607
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-15K16123
[Journal Article] Analysis of individual differences in radio sensitivity using genome editing2016
- Author(s)
  Matsuura S, Royba E, Akutsu SN, Yanagihara H, Ochiai H, Kudo Y, Tashiro H, Miyamoto T
- Journal Title
  
  Annals of the ICRP
  
  Volume: Published online before print Issue: 1_suppl Pages: 1-7
- DOI
  10.1177/0146645316633941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15082, KAKENHI-PROJECT-15H04321, KAKENHI-PROJECT-26701006, KAKENHI-PROJECT-15K15017
[Presentation] 放射線被ばくに起因する消化管腫瘍の評価法の確立2019
- Author(s)
  柳原啓見, 山崎隼輔, 山田裕, 森岡孝満, 鶴岡千鶴, 甘崎佳子, 上西睦美, 遠坂歌子, 島田義也, 柿沼志津子
- Organizer
  第56回アイソトープ・放射線研究発表会
- Data Source
  KAKENHI-PROJECT-18K18197
[Presentation] 消化管腫瘍モデルマウスを用いた放射線の被ばくに起因した腫瘍の評価2019
- Author(s)
  柳原啓見, 山崎隼輔, 山田裕, 森岡孝満, 鶴岡千鶴, 甘崎佳子, 上西睦美, 遠坂歌子, 西村まゆみ, 島田義也, 柿沼志津子
- Organizer
  第34回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-18K18197
[Presentation] Development of a method for distinguishing radiation-induced and spontaneous intestinal tumors of C3B6F1 ApcMin/+ mice2019
- Author(s)
  Yanagihara H, Yamazaki S, Yamada Y, Morioka T, Tsuruoka C, Amasaki Y, Kaminishi M, Enzaka U, Shimada Y, Kakinuma S
- Organizer
  65th Annual Radiation Research Society Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18197
[Presentation] Estimation of radiation-related cancer risk based on signature mutation using a murine model of intestinal neoplasia2018
- Author(s)
  Hiromi Yanagihara, Shunsuke Yamazaki, Yutaka Yamada, Takamitsu Morioka, Chizuru Tsuruoka, Yoshiko Amasaki, Mutsumi Kaminishi, Utako Enzaka, Yoshiya Shimada, Shizuko Kakinuma
- Organizer
  the 64th Annual Radiation Research Society Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18197
[Presentation] ゲノム編集法を用いたNBS1 SNP導入細胞の作製と放射線感受性の評価2016
- Author(s)
  柳原啓見、宮本達雄、Royba Ekaterina、Akutsu Silvia Natsuko、山本　卓、松浦伸也
- Organizer
  第59回日本放射線影響学会
- Place of Presentation
  広島
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K15082
[Presentation] ゲノム編集法を用いたNBS1 SNP導入細胞の作製と放射線感受性の評価2016
- Author(s)
  柳原啓見、宮本達雄、Ekaterina Royba、Silvia Netsuke Akutsu、山本卓、松浦伸也
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  広島
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K16123
[Presentation] Application of genome editing technology into radiation biology for understanding individual difference of radiosensitivity.2016
- Author(s)
  Royba E, Akutsu SN,Yanagihara H,Hosoba K,Ochiai H,Kudo Y,Tashiro S, Miyamoto T,Matsuura S
- Organizer
  The 5th International symposium of Phoenix Leader Education Program for Renaissance from Radiation Disaster.
- Place of Presentation
  東広島
- Year and Date
  2016-02-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15017
[Presentation] Impact of mutations in ATM gene on individual radiosensitivity in Ataxia-Telangiectasia family members.2016
- Author(s)
  Royba E, Akutsu SN,Yanagihara H,Ochiai H,Kudo Y,Tashiro S,Miyamoto T,Matsuura S
- Organizer
  The 5th International symposium of Phoenix Leader Education Program for Renaissance from Radiation Disaster
- Place of Presentation
  東広島
- Year and Date
  2016-02-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15017
[Presentation] ゲノム編集法を用いたNBS1-SNP導入細胞の作製と放射線感受性の評価2016
- Author(s)
  柳原啓見、宮本達雄、Ekaterina Royba、Silvia Natsuko Akutsu、山本卓、松浦伸也
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  広島
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K15017
[Presentation] ゲノム編集法を用いた放射線感受性の個人差を規定する遺伝的素因の同定2015
- Author(s)
  宮本達雄、Ekaterina Royba、Silvia Natsuko Akutsu、柳原啓見、落合博、工藤美樹、田代聡、山本卓、松浦伸也
- Organizer
  第40回中国地区放射線影響研究会
- Place of Presentation
  東広島
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-15K15017
[Presentation] ヒト培養細胞における1本鎖DNAを用いた簡便な放射線感受性候補SNP導入法の開発2015
- Author(s)
  宮本達雄、柳原啓見、落合博、山本卓、松浦伸也
- Organizer
  第56回原子爆弾後障害研究会
- Place of Presentation
  広島
- Year and Date
  2015-06-07
- Data Source
  KAKENHI-PROJECT-15K15017
[Presentation] Custom-made system for estimation individual difference of radiosensitivity.2015
- Author(s)
  Royba E, Akutsu SN, Yanagihara H, Ochiai H, Kudo Y, Tashiro S, Miyamoto T, Matsuura S
- Organizer
  The 74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K15017
[Presentation] Generation of SNP-knock-in Cells Using CRISPR/Cas9 System for Elucidation of the Effect on Radiation Sensitivity.2015
- Author(s)
  Yanagihara H, Miyamoto T, Royba E, Akutsu SN, Matsuura S
- Organizer
  ICRR2015
- Place of Presentation
  京都
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16123
[Presentation] Generation of SNP-knock-in Cells Using CRISPR/Cas9 System for Elucidation of the Effect on Radiation Sensitivity.2015
- Author(s)
  Yanagihara H, Miyamoto T, Royba E, Akutsu SN, Matsuura S
- Organizer
  The 15th International Congress of Radiation Research
- Place of Presentation
  Kyoto
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15017

1. Miyamoto Tatsuo (40452627)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. MATSUURA SHINYA (90274133)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results

Yanagihara Hiromi 柳原 啓見

Research Projects

Research Products

Co-Researchers

量子センサ技術と機械学習による放射線影響評価の新しいアプローチPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An evaluation of the effects of low-dose and low-dose-rate exposure on intestinal tumors by radiation mutation signaturesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

モデル生物を用いた放射線感受性候補SNPの検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis underlying ciliopathy in 13 trisomy syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Telomere function in premature aging phenotypes of BubR1 deficiency

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The establishment and its application of the evaluation system of disease-associated SNP using a reverse genetics techniquePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Rescue of 21 trisomy in Down syndrome cells using spindle assembly checkpoint

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 日本臨牀 73/ 増刊6 家族性腫瘍学2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Analysis of individual differences in radio sensitivity using genome editing2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 放射線被ばくに起因する消化管腫瘍の評価法の確立2019

Author(s)

Organizer

Data Source

[Presentation] 消化管腫瘍モデルマウスを用いた放射線の被ばくに起因した腫瘍の評価2019

Author(s)

Organizer

Data Source

[Presentation] Development of a method for distinguishing radiation-induced and spontaneous intestinal tumors of C3B6F1 ApcMin/+ mice2019

Author(s)

Organizer

Data Source

[Presentation] Estimation of radiation-related cancer risk based on signature mutation using a murine model of intestinal neoplasia2018

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集法を用いたNBS1 SNP導入細胞の作製と放射線感受性の評価2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゲノム編集法を用いたNBS1 SNP導入細胞の作製と放射線感受性の評価2016

Author(s)

Yanagihara Hiromi 柳原啓見